LOCUS       DAVBNZ010000001        75375 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000001 DAVBNZ010000000
VERSION     DAVBNZ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75375
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.001"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(141..1010)
                     /locus_tag="VQ860_000001"
     CDS             complement(141..1010)
                     /locus_tag="VQ860_000001"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET3118513.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(1012..2298)
                     /locus_tag="VQ860_000002"
     CDS             complement(1012..2298)
                     /locus_tag="VQ860_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET3118514.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ860_000003"
     CDS             complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ860_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET3118515.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(3386..4420)
                     /locus_tag="VQ860_000004"
     CDS             complement(3386..4420)
                     /locus_tag="VQ860_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3118516.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGHELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(4449..5882)
                     /locus_tag="VQ860_000005"
     CDS             complement(4449..5882)
                     /locus_tag="VQ860_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET3118517.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(5898..6884)
                     /locus_tag="VQ860_000006"
     CDS             complement(5898..6884)
                     /locus_tag="VQ860_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3118518.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(6886..7989)
                     /locus_tag="VQ860_000007"
     CDS             complement(6886..7989)
                     /locus_tag="VQ860_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET3118519.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(7979..8824)
                     /locus_tag="VQ860_000008"
     CDS             complement(7979..8824)
                     /locus_tag="VQ860_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3118520.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKKVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ860_000009"
     CDS             complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ860_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET3118521.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ860_000010"
     CDS             complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ860_000010"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3118522.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(11219..11695)
                     /locus_tag="VQ860_000011"
     CDS             complement(11219..11695)
                     /locus_tag="VQ860_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET3118523.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ860_000012"
     CDS             complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ860_000012"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET3118524.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(13063..13401)
                     /locus_tag="VQ860_000013"
     CDS             complement(13063..13401)
                     /locus_tag="VQ860_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET3118525.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(13412..14515)
                     /locus_tag="VQ860_000014"
     CDS             complement(13412..14515)
                     /locus_tag="VQ860_000014"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET3118526.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ860_000015"
     CDS             complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ860_000015"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET3118527.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(15701..16768)
                     /locus_tag="VQ860_000016"
     CDS             complement(15701..16768)
                     /locus_tag="VQ860_000016"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET3118528.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(16787..17641)
                     /locus_tag="VQ860_000017"
     CDS             complement(16787..17641)
                     /locus_tag="VQ860_000017"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET3118529.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATDTNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(17631..18308)
                     /locus_tag="VQ860_000018"
     CDS             complement(17631..18308)
                     /locus_tag="VQ860_000018"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET3118530.1"
                     /translation="MKLIVSVMPRSLEEAQALDDTRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(18305..19468)
                     /locus_tag="VQ860_000019"
     CDS             complement(18305..19468)
                     /locus_tag="VQ860_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET3118531.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHHFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(20155..21789)
                     /locus_tag="VQ860_000020"
     CDS             complement(20155..21789)
                     /locus_tag="VQ860_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118532.1"
                     /translation="MRLKVIKKLVDINILYSSQDANLANPRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLPSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(21770..22519)
                     /locus_tag="VQ860_000021"
     CDS             complement(21770..22519)
                     /locus_tag="VQ860_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118533.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            22698..24152
                     /locus_tag="VQ860_000022"
     CDS             22698..24152
                     /locus_tag="VQ860_000022"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET3118534.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAEDAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHMEAFQVIEVDPVDRTVELGEPFTINGWTSFTFYGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKSVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ860_000023"
     CDS             complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ860_000023"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET3118535.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLVIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDVVAGKL"
     gene            complement(26881..27366)
                     /locus_tag="VQ860_000024"
     CDS             complement(26881..27366)
                     /locus_tag="VQ860_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET3118536.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(27641..27880)
                     /locus_tag="VQ860_000025"
     CDS             complement(27641..27880)
                     /locus_tag="VQ860_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118537.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(28141..29211)
                     /locus_tag="VQ860_000026"
     CDS             complement(28141..29211)
                     /locus_tag="VQ860_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3118538.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(29208..29981)
                     /locus_tag="VQ860_000027"
     CDS             complement(29208..29981)
                     /locus_tag="VQ860_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3118539.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(29978..30784)
                     /locus_tag="VQ860_000028"
     CDS             complement(29978..30784)
                     /locus_tag="VQ860_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3118540.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(30765..31922)
                     /locus_tag="VQ860_000029"
     CDS             complement(30765..31922)
                     /locus_tag="VQ860_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118541.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ860_000030"
     CDS             complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ860_000030"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET3118542.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(33099..33844)
                     /locus_tag="VQ860_000031"
                     /pseudo
     CDS             complement(33099..33844)
                     /locus_tag="VQ860_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(33854..34585)
                     /gene="budA"
                     /locus_tag="VQ860_000032"
     CDS             complement(33854..34585)
                     /gene="budA"
                     /locus_tag="VQ860_000032"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET3118543.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKESGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADIATHQPEYSRDNV
                     AGTIVGFWTPQIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            34727..35998
                     /locus_tag="VQ860_000033"
     CDS             34727..35998
                     /locus_tag="VQ860_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET3118544.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(36018..36844)
                     /locus_tag="VQ860_000034"
                     /pseudo
     CDS             complement(36018..36844)
                     /locus_tag="VQ860_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            complement(37001..37654)
                     /gene="phoU"
                     /locus_tag="VQ860_000035"
     CDS             complement(37001..37654)
                     /gene="phoU"
                     /locus_tag="VQ860_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3118545.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(37666..38424)
                     /gene="pstB"
                     /locus_tag="VQ860_000036"
     CDS             complement(37666..38424)
                     /gene="pstB"
                     /locus_tag="VQ860_000036"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3118546.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(38437..39240)
                     /gene="pstB"
                     /locus_tag="VQ860_000037"
     CDS             complement(38437..39240)
                     /gene="pstB"
                     /locus_tag="VQ860_000037"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3118547.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(39251..40135)
                     /gene="pstA"
                     /locus_tag="VQ860_000038"
     CDS             complement(39251..40135)
                     /gene="pstA"
                     /locus_tag="VQ860_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3118548.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(40125..41042)
                     /gene="pstC"
                     /locus_tag="VQ860_000039"
     CDS             complement(40125..41042)
                     /gene="pstC"
                     /locus_tag="VQ860_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3118549.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(41042..41920)
                     /gene="pstS"
                     /locus_tag="VQ860_000040"
     CDS             complement(41042..41920)
                     /gene="pstS"
                     /locus_tag="VQ860_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET3118550.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(42494..43798)
                     /locus_tag="VQ860_000041"
     CDS             complement(42494..43798)
                     /locus_tag="VQ860_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET3118551.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEVVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(43799..44572)
                     /locus_tag="VQ860_000042"
     CDS             complement(43799..44572)
                     /locus_tag="VQ860_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET3118552.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(44562..44840)
                     /locus_tag="VQ860_000043"
     CDS             complement(44562..44840)
                     /locus_tag="VQ860_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET3118553.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(44840..45241)
                     /locus_tag="VQ860_000044"
     CDS             complement(44840..45241)
                     /locus_tag="VQ860_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET3118554.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQQ
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(45451..46068)
                     /locus_tag="VQ860_000045"
     CDS             complement(45451..46068)
                     /locus_tag="VQ860_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET3118555.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(46058..46831)
                     /locus_tag="VQ860_000046"
     CDS             complement(46058..46831)
                     /locus_tag="VQ860_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET3118556.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(46842..47579)
                     /locus_tag="VQ860_000047"
     CDS             complement(46842..47579)
                     /locus_tag="VQ860_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET3118557.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(47584..48714)
                     /locus_tag="VQ860_000048"
     CDS             complement(47584..48714)
                     /locus_tag="VQ860_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET3118558.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     YGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(48798..49187)
                     /locus_tag="VQ860_000049"
     CDS             complement(48798..49187)
                     /locus_tag="VQ860_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3118559.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(49203..49586)
                     /locus_tag="VQ860_000050"
     CDS             complement(49203..49586)
                     /locus_tag="VQ860_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET3118560.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(49587..50375)
                     /locus_tag="VQ860_000051"
     CDS             complement(49587..50375)
                     /locus_tag="VQ860_000051"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET3118561.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(50368..51303)
                     /locus_tag="VQ860_000052"
     CDS             complement(50368..51303)
                     /locus_tag="VQ860_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET3118562.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(51433..51609)
                     /locus_tag="VQ860_000053"
     CDS             complement(51433..51609)
                     /locus_tag="VQ860_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET3118563.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(51749..52456)
                     /locus_tag="VQ860_000054"
     CDS             complement(51749..52456)
                     /locus_tag="VQ860_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET3118564.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            52607..53635
                     /gene="queA"
                     /locus_tag="VQ860_000055"
     CDS             52607..53635
                     /gene="queA"
                     /locus_tag="VQ860_000055"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET3118565.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKMETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(54296..54685)
                     /locus_tag="VQ860_000056"
     CDS             complement(54296..54685)
                     /locus_tag="VQ860_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3118566.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(54739..55430)
                     /locus_tag="VQ860_000057"
                     /pseudo
     CDS             complement(54739..55430)
                     /locus_tag="VQ860_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(56145..56696)
                     /locus_tag="VQ860_000058"
     CDS             complement(56145..56696)
                     /locus_tag="VQ860_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3118567.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(57046..57870)
                     /gene="nadE"
                     /locus_tag="VQ860_000059"
     CDS             complement(57046..57870)
                     /gene="nadE"
                     /locus_tag="VQ860_000059"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET3118568.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(57867..59327)
                     /locus_tag="VQ860_000060"
     CDS             complement(57867..59327)
                     /locus_tag="VQ860_000060"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET3118569.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(59443..59931)
                     /locus_tag="VQ860_000061"
     CDS             complement(59443..59931)
                     /locus_tag="VQ860_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118570.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(59921..60130)
                     /locus_tag="VQ860_000062"
     CDS             complement(59921..60130)
                     /locus_tag="VQ860_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3118571.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(60516..60996)
                     /locus_tag="VQ860_000063"
                     /pseudo
     CDS             complement(60516..60996)
                     /locus_tag="VQ860_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(61156..61890)
                     /locus_tag="VQ860_000064"
     CDS             complement(61156..61890)
                     /locus_tag="VQ860_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118572.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGLAG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRCLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLD
                     IESSQIVLAVLKKLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFWDIV"
     gene            complement(62225..62695)
                     /locus_tag="VQ860_000065"
     CDS             complement(62225..62695)
                     /locus_tag="VQ860_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET3118573.1"
                     /translation="MDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQ
                     LFGARRKIPEYKFVAEVISYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDL
                     HEAKGNKIDRAPNPMELLTIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            complement(62716..62955)
                     /locus_tag="VQ860_000066"
     CDS             complement(62716..62955)
                     /locus_tag="VQ860_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3118574.1"
                     /translation="MRDANRGGCSQSCRWKYDLYDMPFGKERKSLQGEIPEEFSMSAV
                     DMSMIDHIPDMIENGVDNLKIEGRMEWSLFTTYQQ"
     gene            complement(63204..63515)
                     /locus_tag="VQ860_000067"
     CDS             complement(63204..63515)
                     /locus_tag="VQ860_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118575.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(63530..64816)
                     /locus_tag="VQ860_000068"
     CDS             complement(63530..64816)
                     /locus_tag="VQ860_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3118576.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            65439..65621
                     /locus_tag="VQ860_000069"
     CDS             65439..65621
                     /locus_tag="VQ860_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3118577.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            65631..65981
                     /locus_tag="VQ860_000070"
     CDS             65631..65981
                     /locus_tag="VQ860_000070"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3118578.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEDLRAVTGID
                     LLSILTDIANKKQG"
     gene            65989..67179
                     /locus_tag="VQ860_000071"
     CDS             65989..67179
                     /locus_tag="VQ860_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3118579.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     DLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(67694..68686)
                     /locus_tag="VQ860_000072"
     CDS             complement(67694..68686)
                     /locus_tag="VQ860_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3118580.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQSNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            68846..70600
                     /locus_tag="VQ860_000073"
     CDS             68846..70600
                     /locus_tag="VQ860_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118581.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            70584..72305
                     /locus_tag="VQ860_000074"
     CDS             70584..72305
                     /locus_tag="VQ860_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118582.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILINGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            72316..72900
                     /locus_tag="VQ860_000075"
     CDS             72316..72900
                     /locus_tag="VQ860_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3118583.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            72900..73595
                     /locus_tag="VQ860_000076"
     CDS             72900..73595
                     /locus_tag="VQ860_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3118584.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIIMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            73583..74947
                     /locus_tag="VQ860_000077"
     CDS             73583..74947
                     /locus_tag="VQ860_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118585.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT        23228 a        16030 c        13687 g        22430 t
ORIGIN      
        1 acaacctcaa aacactgttt tgagcagcct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt ataaacttct tttcacaaaa aggatatgaa accctctggt caagagtttc
      121 cccatcctat cttctattct ttattttgct tctacacgga caccttgggt atcaactctc
      181 aagtcatgca gttttccttt gaaaggttgc ttttccaatt ctgccttaat tgttggcatc
      241 ttgtcatgag aagccagaac cataactgtc ggcccagcac cagaaaggta ggttgcatag
      301 gccccatttt ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa gtcctgacga
      361 tagcgctcat ggaagaggtc tccctcgatt gcttgcccag cggtcaccat gtctcctgcc
      421 aacaaggcag caaccgctac attggcgata gaacttgcag caacagcttc cttataagac
      481 aattttttag gcaagacact acggctgtcg cgagtacgta attcatagtt tggaatgtaa
      541 gctagaaaat cacactctgg aaagtctgct acgatagcag agacttgccc ttcaacagaa
      601 cttgcaataa cgagattacc ataaatggct ggagccacat tgtcaggatg cccttcaatc
      661 ttggtcgcta actgcaattt ttcatggtct gataagttga gttgacccag ttggttggct
      721 agttcaatcc cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc caaagggaca
      781 tcactggtca ttttcaagcg tcttggttgc aagtctggta caatttgcaa agcgattttg
      841 agcaagagat tacgctcatc atgtggaatc catttgccaa tctggtgttc aatcagccac
      901 tcatctcgtt cttcgcagac ctcaatttga agatacttgg ttacagctac accgaccgag
      961 tcaaaacctg gcccgatatt ggcactggtt gcaggtacaa taatcttcat cttattctcc
     1021 tagcaccttg aaggtattca agaggtcgaa ttctgaaacc ttcttcaatt cagctgagac
     1081 attttcaagc tgggctttat taatcttgtg tgtgatgata acgacacgcg ccttgtcacc
     1141 ctctttgcca tcttgaagga tttgcttaaa ggaaatatct tgagcattga agatttcagc
     1201 caacttcaag acctgacctt ttgagtctag agccaagatt gagaaatagt agtttgcttt
     1261 gacatcttca ggatttgcca agaccaagtc acggctatat tcgttgaagt ctttgccaat
     1321 agtaccatca ttcaaacgac gaacgatacg gacaatatca gctacaacac ttgttgcagt
     1381 tggtttttga ccagcacctg gtccgtagta catagactca ccaataccga tagattctac
     1441 aaagacagcg ttcattacgc cattcacact agcaagtggg tgcgctttag gtaggaaggt
     1501 tggagtcact tctgcagcaa tacctgaaga agtttcctca atagaaccaa ccaatttcac
     1561 tacgtaacca agctcttgag ctacagctac gtcttctggt gtgatattgc ggattccctt
     1621 gtgggctaca tcatcaaagg caatcttcat gccaaaggca aattggctca aaataaccat
     1681 cttgtaggct gcatcaatcc catctacgtc attcgtcgga tcgctttctg caaatcctag
     1741 acgttgtgct tccgcaagag catcatcgta agaccagcct tcttccacca tcttggtcac
     1801 catgaagttg gaagttccgt tgactactcc aagcacgcgc gtaattttat cagaagccaa
     1861 ggaatttgct aaagtacgaa gaattggaat cccaccagca actgctgctt cgtagtaaag
     1921 tgctaccttg ttagcttgag cgatttctag caattctgcg ccatggacag ctaaaaggtc
     1981 cttgttagca gtaacaacgt gttttccagc ttccaaggca cgagtgataa aggttttagc
     2041 aggctcaata cgccccatca attccactac gatagtaata tcctggtctg ataaaatatc
     2101 atccacattg gttacaaagt taaagtcatt ccctgctgca agcaagcgat ttttttcatc
     2161 ttcatccttg accaatacct tagcaacttt gatatctgaa tgtgctgatt gattaatttt
     2221 tcctccattt tcctttagga ggaaaggcac accacttgca acggtaccaa atcctagtaa
     2281 agcaatttta actgtcatct ttatctcctc gaaattttct aatatagcca ttataacaga
     2341 attttgtgaa aattcctatt atagtaaatc actatttcag tataaaaaga aaaaacgaat
     2401 cagacgattc gctcttctta aaatctgaaa atagctttcc agaaaggatt agccgatttt
     2461 ttgcagattg agcactgcat cgtgactcat caagacttga ccatactctt gtaagactga
     2521 gcgactgata tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc aagctggata
     2581 tgggcttgga tgattttcaa tatccactaa aatggtcaaa taatagcgct cgttcatttt
     2641 gtagagttca gaagtttcca tttcaaaagt cactgtcttg gcaaaagcta ccaagtcagc
     2701 caacttagca aaagaaagga tgtagtagat gtaaggttct ttcttactct cagcttcttg
     2761 ttcagcctgc tcttgctctt cttccttggc ttcaacttgc tcaagagatt gaatggcttc
     2821 gatatcatcc ttggttttgt ctgctatgct tttttccagg gttttgataa attcatctgg
     2881 agacatttga gccaattctt ccatatctgg caaatccgat aagtcttcaa aatctagatt
     2941 ttggtcaatc tttgacttgg tcacaaagac atctacctta tcaggttttg gagtcacacg
     3001 gaagctcaac atgcctgtat ccagaaagct atcaggcatc tctagctcat ccaagatagc
     3061 ataaaagaac tcttctgttt tttcttgagg aacgagaaag tcagcaatct ccattccacg
     3121 atccatcaaa tcctctaaag acatcgtgat ttttaaagtt gtatcactaa tttgtttcat
     3181 tttcattgct agtaacctca tactttcagt tctatctatt atactagatt tttacgattt
     3241 tatcaaaaga aggctcctct atacggatag attttcccta gggtctttct ataggagact
     3301 ccaaaagaaa atttctgcag acagatagaa aaagccttca aaatcggctc ttagccgatt
     3361 ttgaagacct tatacatcag aatacttata atttaaaggt tgctacaccg aggatagaac
     3421 gatttaagtt tctgagaatt tgaagacttt gctcaaattt cttataacga gtcactccgt
     3481 actcttcaac aagaaggact gtatctcttt ccaaaagaga tgatacatcc tgtaaatcta
     3541 caaaatgcat tccttttaaa gcttcttgac tctgtttcaa tttatctagg atagctttat
     3601 ttgagctaac gatggtcaat tcgtgtccag tatttttgta tgacaaaaca tctgctaggt
     3661 tagcaattgt tgtaatctct gttacaaaat caatttgata ctgagaaaaa tcacctactc
     3721 tattgattgt tggattaaag agataaacta acacatttcc catcacaacc aaaatcacac
     3781 aaaccactcc aataacaact aaacgaagaa tcagattttt cacatttaag ccaagcgctg
     3841 tttcaccatt tgcgttcaat tctttagagt tgatggtttc cagtttttca attttcacat
     3901 ttgcataggc atgtttaaat ttctcaatca acccatcaat ttttttctct aacaagtcat
     3961 tggcatcttt acttgatgtc aaaattttca caccaacccc tgcatcgtca atcatatagt
     4021 agacggtcaa ttttttccac caatagtcat tcgttgaatt tttcaaggtt gtttctgtcg
     4081 tgtctaattc actggcaatt tttttcaact cactgggttc tacatcattg aaaagataag
     4141 ctccattcaa attaccatca atcaatttcc cataaaaatc actataacca ccaatttgat
     4201 gattcaaaat cgttttggcc gactcttttg gaggagtgat tttatagata agataagttg
     4261 aataacttgt tgtatctttg acagtgtttt tattcctaac tgctttaatt gtaaatggta
     4321 cagcaatgag agcaaataaa gcgatgagag ctaaaatatt tgcttttcgc tttttataaa
     4381 gatttgcaaa caaatcagct actgaataat gttcaaacat gatttttttc tcctttgttt
     4441 agtagatact agttttcctt tgtaagcatt tttgctacaa atataatcac aagaacaatt
     4501 ccccagaatt gcattgtaaa taaattgaag aaactttctg aaaagctgct tcttggcata
     4561 aagaatagat tattcaagat gagtagggat aaagcaaata ggattgtcct tgagcgatag
     4621 gctacttgca gcatggctat aaataatacg ccgagtaaga aactaagcag aaagactcca
     4681 atcataccat agtcggtata caactccatg atataactac ttccgatacc atgccctttc
     4741 aagtattcct tgttcaagac aagataggat agattgtggg cataactatt actatcaata
     4801 gctagttcca cactattggt tgtatgttca aaggcttttc ctccgaaaat ggctcccaaa
     4861 ctcccccttg caaaataatc aagaacagga ccaaaagtaa aattacggaa atctcggtaa
     4921 gggaggctac tgttaaatag aaaacctcga gccagaacac caaaactagt tccttgttta
     4981 tagataaagt caagtaagat atcccagaaa cctgtatggg aaacttggac attatcccgt
     5041 acataattaa gtactcccat cgctaacatg agaataggag aacctacaaa aatcgctaac
     5101 ttttctttaa acccaatcca ttttcctttt tcagtttgct cccgcataaa gtaataaaca
     5161 aaagcaaata aaatacttaa aataaaggga tttcgtgtcc caattgccaa atgaatagta
     5221 ttagctgcaa taaaggagac aagcactgct gtggcctgca atttctttgg cttggttgcc
     5281 agatacatac acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa ataaggcagt
     5341 ttactttcaa aatttgcata gtaggcatag taggaagtct gcaaacgata caagagccgt
     5401 tcaaataacc gaatgaaata gaaaggatag gttagaagaa aaactcctag tgatacaaag
     5461 cgtaaccgct tgatataaac ctcttttaga gaatttccta tatttgctac ttttattttc
     5521 ttcctagcta tgaagtaacg agccaggacg cctcctgtgg tcaagcccag aatcgaaacc
     5581 atgacaacta taaaggcaaa acgataggct attggatgat aggtatccaa agcaccatcc
     5641 ctaaaataat caatggtcgg tcttgatacc agaaatacaa aaatggttaa atagaaaata
     5701 aaatggatta agtaatactt gatatcattc caacaagcaa ttaagctact aaccaacaag
     5761 aacaataaag tagaaagtaa gctaacatta ttattattaa acagatacac aattccactt
     5821 actagcgtca aggtataact gactatggtc aaactaaata ataatcgttt cccatcaatc
     5881 acttggtcac ccccgttcta atgtaatttt ttagattttt caatattttt cagtaataag
     5941 aatcggtata aggaaatatt tatgaatagg gccaaagcac taattcttct ccccttacgg
     6001 aaaattggat tcctagaaat agcaaaagca tagcctttta aaaaacgatg aatctgagaa
     6061 taggcttcaa actgtttata ctgatcatct agcaacatct tatccagaat aaagaagtga
     6121 gcataggcca atctgaaaaa agcgacctct ttcaagtcag gatagttttt cacaacttca
     6181 ttataaaact tttggtagat atcaatatag gctaaatcct tctttgcata gggtttggtc
     6241 gtaatactat cccctctatg gaaatagtaa taatagggtt tagtattaac cacatacttc
     6301 ttggccaact tgattaaatc aaaatggtaa taggcatctt cgtaaatcaa ccccttagga
     6361 aaggataggg cagttgcaat ttgtctcttg attagcttat tgcaaatcgt cccaggtatt
     6421 ttttcaccta tgaggtattc ctttagaaat gtttgagaat cacagacaaa atagtcatcc
     6481 tgattggctg actgtgggct ttcatcatta gcatagacat tcatgacacc acagcttgaa
     6541 acatccgcat cttcttgaac taattgctca tataagctct gaatcatttc tggatggata
     6601 taatcatctg agtcaataaa aatcagataa tccccgtgag cctgcttcat cccatcattt
     6661 cgtgcttgcg acaatccttc gttcttttta tgaagcactg acaccctgtc atcttgttca
     6721 gcgattgaat cacacaagcg accactttca tctgttgcac catcatcaac aagaataatt
     6781 tccagatttt gataggtctg cttctgaatg gaagctatcg atttttctag gtactgcgcc
     6841 acattataga ctggcacaat cacactaatt aatgcagttt ccatgctact cctctaatag
     6901 tttttctact tgttcgattt gttttgtaat tgtaaattgt tgaatgaatt ggctagcctc
     6961 atcgacatta aagtttgagg cagaagtcat gtaattagta atcgcctgag ctgcctcttg
     7021 attgctctca atgatttgtc caaatcgtcc ttcttgggat aattcctcag cccctccaac
     7081 gtccgtagag ataaaaggga gtcccagact caaggcctcc acatacactc caggaaagcc
     7141 ttcttgttta gacatagaca agagaacttt cgtctgagat aaatactgat aaggattttt
     7201 ttgataacca aggaaatgta catagtcctc aatctcatac tctttgactc gttttttcag
     7261 ttcctcttcc atatcaccag ccccgataaa atagagatga tagttttttc cctcttggtg
     7321 taataatcgt atcacttcca ctacacggtc agaaccctta ttttcctcaa tccgtccgat
     7381 agtacagata ctttgaggag caatctcgat atcgatcttc tcttgagatt tttctagaat
     7441 agtctgaaaa tcatatccat tgtagattgt ctgtaattta gaagcataat ctggataaac
     7501 ttccttgata gaattgctgg tcttttttga aatccctaca attgtattcg cagcatccaa
     7561 ctggcttcta tgtgattctc ttttagagct atccttaaga agttcttcaa tacttccatg
     7621 aatccaagat atcttcttga cttctcttct tttagagaac aacagtggtg gattcataat
     7681 ggtaaaagaa acttcaacat cataatcatc ttttacaagc aaacgacgag tcagtcttgg
     7741 aaaataaatt ctcattctcc acaaaaaagc tcgtaaccat ctggtttggc gataatcttg
     7801 aagggatttt aaaatgcgta catgctttgg aacagattca tatcccttgt caaagtgctc
     7861 catttcaaga atatcaatat catacttttc tggatccaga tttgaaacaa tggttgatag
     7921 aatcttctct gcaccacctc caagagaaaa agaccacata aaaaataaga tttttttctt
     7981 agccaccata ttctcccttg tattctgtat aagacttatc catatcagcg atgacagcat
     8041 catgatgcgg taccttcttg tctgctggtg gaggcgtcat ataatcccca aaagcagttc
     8101 tgagatagac atcatagccg attggaatag gcatctctgt tccttcaaat ggcaagaaaa
     8161 gattgtcttc aaaagacgtg attgggtact tgtttctcat gtagccagga cctgagcata
     8221 attctgtaat gccatcacaa tcagccaaat catacttagt catttctttc tcagcttttt
     8281 tccagatgcg ataacggaga gattttggag tcaaacccag taaaatgcga cttccccatt
     8341 tcatgagagc accatgcttt tctggaatag tttgcgcaca aaagagtgaa taaatcaagg
     8401 cccaacgaac ctgttttttc cgctcagctg gatttttcgg ataataatcc aaaggcaaaa
     8461 catccaaggc cagaccatgt ggcaaatcca aatcctgctg ataaggcttg atacaggtgg
     8521 tttccttgtc acgaatggta ataaaaagat tacgatcaac aaaatccttg tgactctttg
     8581 acaagaaata acgttcatct gcataacgag gccataattc tgctaatttc tcataatctt
     8641 tacgaggcat aaaaaagtct aggtcgtcgt cccaaggaat aaatcccttg tttcgaaggg
     8701 caccaatagc gcctccgcca cagagataac agagcaaatc atgttcttta caaaaggcca
     8761 caaaatattc agccatctcc agactacgag cctgaattgc ttttaaatca gtcatattgt
     8821 tcattattct ttctatcgta tcgtttcatt ataccacaaa caaggggtga aaatctattg
     8881 cagactgtaa aaaatcaaag cctgactgct atccaaatag ctatcaaact ttgatttttc
     8941 tgtcttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtata
     9001 ggtaactgac ttcgtcagtc ttatctacaa cctcaaaact gtgtttttag cagcctgcgg
     9061 ctagcttcct agtttgcact ttgattttca ttgagtatta tcttatctca agcccatttg
     9121 agcgagcttg gtttgatatt tgttttgatc aaccagcaag cccaagcctc cataaacatc
     9181 ataggcatct acccagtcac ccagttctgg aatcgtcaat ttttcaatac cattttttgc
     9241 tccatccaaa acagataaac cgtttgttag gaggaaagta tagggtacgt tggttgaggt
     9301 catagcaaaa acctttccaa gagcttcaga accagtgaaa agtttagtgg gatctttaat
     9361 ttgctctaaa attgctgtta aaacttgttg ctgtcttttt gtacggccgt aatccgcctc
     9421 atcatcatca cggaaacgag cataattgag cagggtcgag ccattcatct gctgttttcc
     9481 gactttaatg gtttgggttg gagactcagt ctcggtagcg tataaatcat ctccgactgt
     9541 agcttctgtt aggggacgcc cattcaatgt tgaaaattga gcatcaatcg tcaccccatc
     9601 agggaaaagc gtgtcaatcg ctgtggcaaa ggcctggaaa tcaaccaagg cgtagtactt
     9661 aatgtccaag tcaaaattat ctttcaagac ttggcgaacc atttctgccc ctttttgccc
     9721 ctcttgttct cctaactcgt aggctacgtt taacttgtta tctgtctgtt ttctaccgtt
     9781 aatcacttga ctataaccat ctatatagac caaattatca cgcatgaaac tgactagctt
     9841 cattttctta tctgagcccc cgacatttaa taccataata gagtcagttc gtgtctcaac
     9901 actgttctgg ccgattcgac catcagtacc catgattaaa atattaactc catctctagt
     9961 gtcctgacca ttaaagactt ctacttgagc tgcccgggca tcagcagttt tctttgcgct
    10021 agcatcttgg taaccacgca aaaacatgaa taccatggcc aaagccacac agaccaaaag
    10081 tgaaaaaatc accataaaaa ttcgtttaag acggagcttc cgtcttttct tttttggagg
    10141 gaaagagagt gcttgtgatt tggattgtga gcgactccgg ttcgcatagc ttggtaagtc
    10201 aacctgctct tctctttctt gttccaagct agagctacta tttcccctag caagagttag
    10261 cttttcttgc aaataggcaa actcattttt ttctctctca ttgagatagt gaatattttt
    10321 tagcaaataa tcataacgca actgctcatg atgacttaag ggattttctt tactcatctt
    10381 ctctcctttc catggtctga tattggataa ataggatagg cacccagaat tttatactgg
    10441 attccaatcg cttctaattc tttttgggca aagtggacca agtccttatc ggtataatcc
    10501 acatcgataa tgaaaaagta ttcacccagt gctgtcttga gtggacgact ttcaattttt
    10561 gtcaagtcaa ttcctcgcca agcaaaggtc gacagggcct tataaagtgc acctggaagg
    10621 ttgtcaggta atgtcaaggc caaactcatc ttttcagttt gtgcttgcaa gggaatacta
    10681 ggcttttcag ctcctagaac ccagaaacgt gtgaaattgg cttccatttc ctgaatatcc
    10741 tcggcaatca gttccaatcc atattcttca gcagaacttc taggtgcaac tgctgcaaag
    10801 ggctggtctg gatgttcgga aataaaacgg gccgcataag ctgtactagc tgttacctcg
    10861 atttgagcct ctggatattg ttcatcgatg aatttctttc cttgagccaa ggcctgtgga
    10921 tgtgaaaaaa tcttttcaat cttagtatgg cctggaacca ccatcaactg ctgatgaata
    10981 ggctgaacga tttctgctac tgcttggatg tgagcctgat gaaaaagata gtccaaggtt
    11041 tcatgaacac taccctcaat agaattttca actggcacca cagaatagtc cactaatcct
    11101 tgctcataag ccttgatgac atctgtaatg ttagcaaaag cctgcaattc ctcatgagga
    11161 aaagctatct gcacaacgtg gtgtgaaaat gatcccttgg gacctagata agcaattttc
    11221 atcttagttc ctctataatt tcctctgggc ttagcttggt cacatccaaa acccgactag
    11281 ccacttcctc ataccaagcc tgtctttctt gaaaaatagc tactagttct tccttgctat
    11341 tatttagaaa aagcggtcgc tgattgtcct tatcagctgc gatacgttgg tagagggttt
    11401 caaaatctgc tttcaggtag atgttatctg tattagtctt gagtaagtca cgatttctct
    11461 gagaaataac cactcctcct ccagttgaca cgacttggtc tgtttgtagt aaatcagcta
    11521 ggacttctga ttctacctga cgaaaggctg cttctccctt ttcagcgaaa aaattcgcaa
    11581 tggacatacc taggcgcttc tcaatcagag catccatatc aaggtaatta gggtccaagc
    11641 ctcttgcaat agtcgatttt ccagccccca taaaccctaa taacacctta gccatgaatc
    11701 aagctctcca aatcatcaaa gaaactagga tagctggtat tgatggcttc tgcacggtca
    11761 agctccacct ctccatctgc aaccaagagg gctgcgatag ctgtcatcat gccgatacgg
    11821 tggtcaccaa acgtattgac tctagcaccg tgaagagctg atttcccttt gataatcatc
    11881 ccatctgccg taggagtaat atctgctccc atactattta aggcgtctgc cacaacctga
    11941 atacggtctg tttccttgac cttgagctcc tcagcatcct tgataactgt tacaccttgg
    12001 gcttgagtcg caagcagggc aataatgggc aattcatcaa tcaatcgtgg aatcaaagcg
    12061 ccaccaatct ctgttccttt caagtcagaa gactcaacag tcaaggtaga agatttagcg
    12121 actggatcga tttcagttat ttccaatttt ccacccatgg cacgaatgac atcaataata
    12181 ccggtgcgag tttcgttgat ccccacattc tgcagcacta gacgagaatt tggaacaatc
    12241 aaacctgcga ctaaccaaaa ggctgcactg gaaatatctc ctggtacgac caccttctgt
    12301 cctgtcaatt tttgtggccc ttggactgtg attttcttac cgtccacact taaatgacca
    12361 ccaaattgtt tcaacatatc ttcagtatga ttacgggtgc actctttttc gataataact
    12421 gactccccct tagcttgtaa ggctgcaaac atcaaggctg acttgacttg ggcagaggca
    12481 attggcaact cataatgaat aggtcttagg tttttcgtcc cttttaagcg aaggggaggc
    12541 aagtctcgtt cagtttgccc tgaaatgctg acgcccattt ttttcagtgg aagggtcaca
    12601 cggtccatag gacgtttgga aagactatca tctccaaaca tctctacttc gaaatctgca
    12661 ccagcaagga cacctgaaat caggcgaatc gaggtgccag aatttcccat attaagggca
    12721 ttttgtggcg cttttaagcc agccatgcct acaccttgaa tggtaataac cccatcttta
    12781 tcctcaattt caacaccaag gtcacgaaaa acctgcatgg tcgaaagaac gtcttcacct
    12841 cgcagaatat cataaacctt ggtctcaccc tcagccaaac ttccaaagat aatggaacgg
    12901 tggctgatag acttgtcacc tgggacgcgg atactaccat gtaaatggcg aatgtttgtt
    12961 tttagtttca tactggacct catacttgca atacttttac ctattttatc ataaaaagcc
    13021 agaaattcct taaaaattcc tgactttagg atcgttcttt tcttatttca gcaattctga
    13081 aactggttca aaaacaattt tttcaatgtc agaaaggtaa atggccaatt gttgttgctt
    13141 ggtaaagaat tctgacaaga ggctatttcc ttgaatctgt ttaccaaagc cttccatctt
    13201 agcttggaag gacgcatctg gcatttgacc tgtatgtgct agtttttgaa tttcctcttg
    13261 aaaggcaaga tattctgtaa agattttgct tgcctcagca tctgctgcaa tcgcatcttt
    13321 agctgcttta acagccttgt attctggtaa tccgcgtaga ccgcgactga gttcgtttgc
    13381 actatcgtaa atatttgaca tgttcttctc cttatttgat gacgactgta tagtcggtat
    13441 tttctgttat gagatgctca gctctttcca agtcttgagc atttttaaat gaaatttgta
    13501 ggattccgtg aatatcctca cgattttcct cgttgatgtg gatgttaacc aaggaagtcc
    13561 cacgtagcag ttccaaaatc cgcaggatga catcttcttc atcaggaacg tcaacataga
    13621 ggtcgtaaga gctatccaca ccaccacgct tatggatttc catggtctgg cgttgttcac
    13681 gcgcttggtt aaaaaagttc caaatttgct cttcatctcc cttactaatg gcctgaccaa
    13741 tcacttccaa acgttccttg aaatcctcaa ttctatccag aatggtctcg ctattggaca
    13801 agagaatgga ggtccacatt cctggctcgc tttccgcaat tcgggtcata tctcgaaaac
    13861 cacctgccgc aaagcgcctt gccatctcat gctcttgagc atagaccgca gtctgctcca
    13921 tgagactaga agccaaaata tgaggaaaat ggctaatctg agaagtgaca cgatcatgct
    13981 ccttggcatc aatctcgata aaacgagcat gaagacctga aagcagatcc ttcatttcct
    14041 taagcgtgtc ctgacttgtc aggcttgaag gtgtaaagat ataataggca ttttcaaaaa
    14101 gattgacatc tgccgaagca gcccctgtct tgtgactacc agccatggga tgggccccga
    14161 caaagcgaac agacttgcca gccaaatact gctccgccgc atccacaatg gttgacttgg
    14221 tcgaaccagc atctgaaata ataacgcctt ctcgcaaatc caaattggcc aactccttaa
    14281 tgaaagcaat agtttgtttg attggcaagc tgaggataat gacatctgcc aaaggagcaa
    14341 aactagcaaa atcatccgtt gcacggtcaa tcatgccttc tttcaaggcg atatctctcg
    14401 aagcttgact acgattataa cctaaaattt cataatctgg atgatcgcgt ttgataccaa
    14461 gtgccataga ggctccaatc aacccaagac ctgcgatata gattgttttt gccataggaa
    14521 ctccttaata gttctttgta tagtctcggt gtttggctac cgcttctttt agttcctcaa
    14581 gattatctga tgagaatttt tcgaggattt cttgcgccag aaccgttgct acaactgctt
    14641 ccatgaccat tcctgcagct ggaagagcag tcggatcact tctctccacg gttgccttgt
    14701 aaggttcgtg ggtttcgata tccacactca taagaggttt ataaagagta ggaatgggtt
    14761 tcatgacccc acgaacaacg atgggttgcc cattagtcat accaccttca aaaccaccta
    14821 gattattggt acggcgagta taaccgtctt ctttagacca gagaatttca tccataactt
    14881 ggctgccttt acgataacca gcctcaaagc caagaccaaa ttccacccct ttaaaggcat
    14941 tgatagagac aacagcttga gccaatcttg catccaattt tctatcccat tggacatagg
    15001 aaccaagacc aactggaacg cctccgacga ctgtctccac aaccccaccg atggtatcac
    15061 catcacgttt gatttggtca atatagtcct tgatttcctg ttctcgttct tggttaacaa
    15121 tagaaacttc agactgggca gctctttgct taatttcagc gactgtcaga ttttcaggaa
    15181 catcgatttc cttgccacca aagaccacga catggttggc aatctccata tccagctcag
    15241 ccaagaggcg tttggctact gcaccaactg ccacccgcat ggtggtttca cgagctgatg
    15301 aacgctccaa agaatttcgc aaatcatcaa aacggtactt aatcccccca accaaatcgg
    15361 catgacctgg gcgaggatga gtaattttcc gcttgctttt aaggcggtct tcaatgtcct
    15421 ccgcagacat gatgtccagc catttctggt ggtccttatt gatgacatcc atagtaatag
    15481 gcgcccctgt cgtcttcccg tggcgaacgc ccgaagtaaa gacaacctgg tcactctcaa
    15541 tcttcatacg accaccacga ccgtagccac cctgacggcg tctaaggtcc tcattgatat
    15601 cctcagctgt caatggaagt ccagctggaa ttccctcaat aatagctgtt agacgggggc
    15661 cgtgtgattc tcctgcagtt aaatatctca tacactctcc ttattttacc aagtagtctt
    15721 tcatctcttc cagagaaact gggtgaatga tcgctgaacc aagctctggc accaagacca
    15781 atttcaaggt gttaccacgc gctttcttgt catgagtaag agcctgataa agcttgtcaa
    15841 cttcccaatt ttcatagtca acaggcaagc cgaatttctg acacatctct gtgatagatt
    15901 gggtaatgcc agctggcatg aggccttttt cctcagcaac cttggaaatc tgtaccattc
    15961 ccatggcaac agcctctcca tgcatgacct tgccataacc ggcagtcgct tcgatggcat
    16021 ggccaatagt gtggccaaaa ttgaggtaaa gacgaatacc attgtccaac tcatcttcaa
    16081 ccaccatctt gcgcttcacc tgacaagaat gttcaatcaa ggtctctgca tgttccaaaa
    16141 tactctcaac agaaccattc agtcccgtca agagagccca cagttctgga tcctcaatca
    16201 agccatactt gataacttca cccatccctt caatcaactc tctttttccg agggtttcaa
    16261 gaacaagtgg atcaatcaga accccatctg gttgggcaaa ggtccccacc atatttttag
    16321 caaatggtgt gttaacgcct gtctttccac cgatagaaga atcaacctga gctgtcaaac
    16381 tagtcggaat ctgaacaaag tgaatacccc gcatataggt agaggctaca aatccagcca
    16441 ggtccccaac aacgccacca ccaagagcaa cgattccatc gctacgagtc agaccttgct
    16501 tgactagaaa ttcatagact ttctgaacag tagttaaatt ctttctttct tcaccttcta
    16561 agaaatcaaa aacagctacc tgaaaaccag catcttctag gctgagcttg accttctctg
    16621 catagagaga ggctacatgg ttatctgtca caatgactac cttttgcggt tgccagagtt
    16681 ctcgcaacca ctgaccagcc tgggccatac aacctttttc aatctgaata tcataaggat
    16741 gatgaggaat atcgattctg attttcatag gagagtttcc ctttctttat tggtattttt
    16801 ctgttaaaga ctgccaaatc tcttctgtcg gcatttcctt gcctgtccac agttgaaaag
    16861 cttctgcagc ttgatagagt aacattccca gaccattgac tgctggattg ccctgacttc
    16921 tagcccattt caaaaacggt gtttcaaagg gttggtatat gatatctgca actaaaagag
    16981 tttctggtaa gactatgttt tcaggaacag gagaggattg gccatccatg cccacactgg
    17041 tggcattaac tagcaaatcc gactcggcaa tccttgcttg cagttcagaa acatattcta
    17101 aagcacacaa atccacttta aaacctgtct gctcctgtaa cttgtctagg taaggtcttg
    17161 ttttttccat agaaacggaa cgaacaaaga ccgaaatctg actgacgcca tccaaaatag
    17221 cctgtgccaa gattgattta gccgcaccac ctgcacccag cagggtcatc tttttacctg
    17281 aaattgtaaa agaaggcaag cacttaaaaa atcccttgcc atctgtatta tatccaatta
    17341 aattgccatt ctcattgaca accgtattaa ccgcaccaat caagcgcgct tcatcgctca
    17401 gcttatccaa ataaggaatc acctgctcct tatagggcat ggacagattg atgccaaaca
    17461 tctggtagcg acgaatattg gccactgttt ctaccaagtc actcgcttca atctcccaag
    17521 ccacataagc accgttggta tctgtcgcct caaaggctct attgtggatg aagggagaaa
    17581 tagaatgctt aataggattg gcaacaactg cagctaaacg tgtatagcca tcaagcttca
    17641 tccaaaatct ccctgatttt tttcatgcta gctagagaaa tctgcccagg ggcactaacc
    17701 tcatccagac tggcaaaaga ccaactcgaa ccagtcacat ccgcagtgat acgagagacc
    17761 ttgcccacct tacccataga aatggtcaca tattcctgtt caggattgag ggttttaaag
    17821 cctcgtgtat agttcatcaa gtctaagaca tcctgctccg tgtgagccat caccgcaacc
    17881 ttaacaagtt ttggatttag gatcgtcaac tctgacaaga tttccatcat gttctcaggt
    17941 gtttcttgga aattatggta actcaaaaca agatttggga agtccagcat ttcctcaaaa
    18001 acatccttgt agctatagta ctcaaaatca atatagtctg gttgatagag ttgcgcaact
    18061 tccttgatta gatggatata ctcttctgga gaaaggtcga tttctccacc ttcggagcga
    18121 gttcgtagcg tgaaaaccaa ctcacggcct gcgaattttt caaaaatggc tggagctacc
    18181 tgcaaaatcg cttctttagg cagatagtcg gcacgccatt caatgatgtc ggcatccagg
    18241 tacctcgtgt catccagagc ctgagcctcc tctaaacttc ttggcattac tgaaacgatt
    18301 aatttcattt actaaccttc atactaatca ccttgaggta attactactt tcatcttttt
    18361 tattataggc aaaatctgct ggaagaccat atttgtttaa aatctggtaa cttcttcctg
    18421 caaaaccttt atcaatttgt tctgtaaatt tctgacggga aacattggca gcattggtac
    18481 tggcaatgat aatccctccc ggatttaaaa tctcaagact ctgggaaatc aacttgtgat
    18541 aatccttggc cacagagaaa gtttgttttt tattccgagc aaagctaggc ggatctagga
    18601 caatcacatc gtaggtcaag tctttgcgtt tggcatattt gaaatactca aagacatcca
    18661 tgactataaa atgatgctcg tctgtgctga gcccatttgc ctgaaaatgc gcttgagaca
    18721 attctcgtga acgtttggct agatcaacag aagttgtctg gctagctcct cccatggccg
    18781 cagctactga aaaagccgct gtgtaggaaa acatattgag caaggattta cccatagcca
    18841 agccgtcaac taaactaccg cgaacctcat gctggtctag gaaaatgcct gtcatcaagc
    18901 catcattcat aaagacttga tacaggacac cattttctaa aacagtgaaa aagtcaggtg
    18961 cttcttgacc ataaacatgg gcagattcat agtccaaacc cttaaagcgg attttctcat
    19021 aagctcctaa aacctcaggg aaaacctgtc taaaggcttc tgatatagtc tgacgaatct
    19081 gataaacata agagttatac caagaaaaga cggcgtagtc gccataaagg tccactgtca
    19141 gacctccaaa gccatctccc tcttgattaa agagacgaaa ggcagttgtc aaatcatctt
    19201 gatagtaggc gtttctcttt tctttggctt ttctaaacaa cgtttcaaag aaagtttgat
    19261 tgaaggccac cttgtctttg ctgacaaacc agcccaagcc cttgttttgc tgagaaaggt
    19321 aggcagtccc aagaaagttt ccttcctgac cctgcacctc tacttcctga tccttaagat
    19381 tgacattctc aagatcactg gcttctagta aaactagccc cttagcaagc ttcttttcaa
    19441 cccttttgct gactcttatt ctattcataa ctaccattat atcaaacttt tagacaattc
    19501 tcaaaaaaga aactaccctt gcttttttac tcttctttta aaaaatggta tactagactt
    19561 cctgcaaaac taggaagtaa atgtgtaaga atcacaataa aaaatgctct tccgtcttgg
    19621 aggagcattt ctttttatca acgaaaatca aatagcaaac tatgaaacta gcctcaggtt
    19681 aactgtgaga ttataggtag agaggttgaa tcagcaatat gtgtctgtca aatttagtga
    19741 caaaggtagt agaagaaaga tgaagaaata aatctgcttc aataggtatc tggaaaattt
    19801 gattttatag agaagccttt tgttacaaac tcaatatact atcaataaat aatattatag
    19861 aagcaacaat aattataatt tcacctatct gcatcattct atttcgaact ctaaatatat
    19921 gttctatcaa aaatacttgg atcacacaca ttataggaat taacgttttt gaaattgaaa
    19981 aatatcccaa taaataaact ataaacaaca aaaatagaac tatgttatat ttcttattca
    20041 aaacattcct ccctatatat ttttgattac caatcttaat catttacaac tacattctaa
    20101 caaactataa aagcgtttgt cgaactgaat ttatcaagca agcgaccaac cagctcatct
    20161 tttttctatt tctgccaata tgcgtgacag gtaataatga tagccaaaaa tagcaagagc
    20221 aagcaggagg ataagagctc ctactcccaa gctgatggca aggatagggg agagagactg
    20281 aaccaagaat atactcccaa ttacaagggc catcaggatt gcactataaa taaacaataa
    20341 aactatggcg actatgccat ttgaacgatt caccaggtcc gtaatgctac tccaattggt
    20401 tgacagattt ttcacatcct taaaataatg gtgacaagaa aggatgacac tggcaaggat
    20461 ccatgccaca ataaggtaaa tcatcgaaat gatgggcaag cctagatata gagaaagacc
    20521 aagtaaagtc agaattggta aaaaggactg aacagcaaag ataatccaaa atttcacttt
    20581 cacataacga gcaaagtcaa agggtaaact cttcagaaaa tcaacatttt ccctctccaa
    20641 ggacaaggca attgaaggca ggctggtgat attgttattg acaactgcta taaagagagc
    20701 tataaaaaac aagggtaacc agtatggagg atgaatgtct ggaactatct gagaatctcg
    20761 gattttggaa atcagaccga tcatcatgag ataaggaagg aaagcacttg taaaaagcac
    20821 tgtaaccacg ccagtcccct gtcccaagag ggtgaggtgg tagcgtaaaa ccatgcggaa
    20881 aaatcccttt ttagtggttg aaattctctc cttgctgcga cgttcttttt tgaccttctc
    20941 ctcactatta agcaggatca cgtcataaaa acgaggaagg accttctttt tggtcagata
    21001 aagcaggaag agagttagtc ctatccaagc gagcagaccc aatatggctt ctattgaaaa
    21061 aggctccact gctattttgt aaaagatatg aagaggataa aggagaaatg gaatgtctct
    21121 aactttgtca acaatacttc caaaagtcga ctgaagaaag aagataaata ttaaaggtat
    21181 gagaactcct atcccaatca tcacattcga aaaaatagac tgatactttc tgaagaccct
    21241 agtctgagcc aagaaatgta ctgccactac cgtcactaaa gtaacagaga caaataataa
    21301 ggtcaaggac agtagcatca aaggcaaacc cagccaaaga gaaggagcta gactaatata
    21361 gagggctaga aaataagcta ggattggtac aattccagtt agagctggca agaggacaga
    21421 cagtccttta gcaattataa tctctgattc tttaaaagca tagggactat aggaggccaa
    21481 atccttactc tcataaaaga cattgtaaaa tgcagttaaa gaagttgaaa aggcaatcac
    21541 tagtaaaata gcaaccatga aactaaaata aacaggcatt tcctcaaaag gaaaatgaat
    21601 ggctatagta ctaaaaaaga tgagcatcaa gagactggaa aaaatgtaag aacttaggac
    21661 tctagcggaa acatttactt tttttccagt atttttagct tgcttctttc gtgggttagc
    21721 cagattagcg tcttgagatg aatagaggat attgatatca actaattttt taatgacctt
    21781 gagacgcatc tgaaacctcc tcttttctac cagcaaggct aaggtagata ctttccaaag
    21841 actggtctgg gttgtctttt ctcaagtcct ctaccttacc acaataaatc aaatgcccct
    21901 ttttcaaaat agcaatccga tcacagactt gctcagctac ctctagcaca tgagttgaaa
    21961 acaaaactgt cttacctttt tgcgcatgct ccttcatcat ttgcttcaaa tcaaaggcgg
    22021 cctggggatc caaaccagtc aagggttcgt ccaaaaccca aatatcagga tcagacaaga
    22081 gtgccccgat gacaaagact ttctgacgca ttccgtgaga aagagtttca ataacctgat
    22141 agcgattttc agcaaaatca aaaacgttca atagcctagc tagactagcc tccaagtcag
    22201 atctactcag atcataggat gaggcgatca attcccaaaa ttcattggcc gttaagcgta
    22261 aaaataagtc aggcgagtct gctacgtagc caatctttcg tttaatagcc aagcgatttt
    22321 ccgataactc ctgaccgtct accaaaatac gaccactgct gggtgaaatg atactgacta
    22381 gggattttat agtggtcgat tttccagccc cattatgacc aatcaagccc ataatctctc
    22441 cattttcaat ctgcaaattg agattactca aggcctcttt atcaccatac aacttactaa
    22501 cattttgaaa ttcaatcatg ggacaactcc tatctttatc tgtattatat atcgctatac
    22561 tatcactttg atacaaaaaa tcaatacttt attttaagta gttaaaacag tttccttcta
    22621 ttcttacgca aacgtttgcg ctaaccaata ctttatgata gaataaagaa caagattgac
    22681 aagtaagagg aaaaatcatg caaaatcaaa cgctcatgca atactttgaa tggtatctgc
    22741 cccacgacgg tcagcactgg acgcgtctgg ctgaagatgc tccacaccta gctcatctgg
    22801 ggattagcca cgtctggatg ccaccagctt ttaaggcaac caatgaaaaa gatgtcggct
    22861 atggtgtcta tgacttattt gacctaggag agtttaacca aaaagggact gtccgcacta
    22921 agtatggttt caaagaagac tatcttcaag ccattcaagc cctaaaagca cagggaattc
    22981 aacctatggc cgatgtggtt ctcaatcaca aggctgcagc cgatcacatg gaagcctttc
    23041 aggttatcga agtggatcct gtagaccgta cggttgaact tggagaaccc ttcaccatca
    23101 atggctggac tagctttacc ttctatggtc gccaagatac ctacaatgac ttccactggc
    23161 attggtacca cttcaccggt acagactacg atgcaaaacg ccgtaagtct gggatttatc
    23221 tcatccaagg ggacaacaag ggctgggcta acgaggaatt ggtcgataac gaaaacggaa
    23281 actacgacta cctcatgtat gccgacctag actttaaaca tcctgaagtc atccaaaaca
    23341 tctatgactg ggctgattgg ttcatggaaa cgactggtgt agctggtttc cgtttggatg
    23401 ccgttaagca tattgactct ttctttatgc gcaacttcat ccgcgatatg aaggaaaaat
    23461 acggtgacga tttctatgtt tttggtgaat tttggaaccc agacaaggaa gccaatctgg
    23521 actatctcga aaaaacggaa gaacactttg accttgtcga tgttcgtctc caccagaatc
    23581 tctttgaagc cagtcaagct ggcgcaaact atgaccttcg tggcattttc acagatagcc
    23641 tggttgaact caagcctgac aagtctgtga cttttgtcga caaccacgat acccaacgag
    23701 gacaagccct tgagtctacc gttgaagaat ggttcaagcc agcagcctat gccctcattt
    23761 tgttacgcca agacggcctt ccatgtgtct tttacggaga ctactatggg atttcaggcc
    23821 agtatgctca acaagatttc aaagaaatcc ttgaccgcct cctagccatc cgaaaagatt
    23881 tggcctatgg agaacaaaat gactactttg accatgctaa ctgtatcggt tgggtacgtt
    23941 caggtgctga aaatcaatcc ccaatcgcag tcttgatttc aaatgaccaa gaaaacagca
    24001 agtcaatgtt tgtcggtcaa gaatggacta atcaaacctt tgtagattta cttggtaacc
    24061 accaaggtca agttacaatt gatgaggaag gttatggaca attccctgtc tcagctagat
    24121 ccgtaagtgt ctgggcagtc aataccatct aatagctcat aataaccaag ctaggtccaa
    24181 gcggatttgg cttttttgta gtcaaaaaag acctacccaa atggatagat ctttacttga
    24241 ttacaattta cctgctacta catccaataa ttcttggatc ttagcttggt tgcttcctcc
    24301 tgccatggcc atgtctggtt taccaccacc acgtccatcg atgattggtg ctaattcttt
    24361 gacaaggttt cctgcatgaa ggtcttttgt cttgcttgct acaaggacat tgactttgtc
    24421 accgatagcg gcaactagga caagaagatc agagtagtct ttttgtttcc agttatctgc
    24481 aaaagtacga agggcaccgg catcggatac agacacttga ctagcaatgt aacgatgacc
    24541 gttgacttcc ttagcatctt tgaagatatc gcctgcggct gcagctgcgg ctttttcttt
    24601 caactcagca ttttcttttt gaagttgacg aagttgttct tgaagtcctt ctaccttgtg
    24661 aggtacttcc ttgacttgag gtgctttcaa ggttgctgcg acagctttaa gagcatcctc
    24721 ttgttcacga taggcttcaa aggcttcctt accagtcact gccaagatac ggcgagttcc
    24781 tgaaccgatt ccttcttctt tgacaatttt gaagagacca atctcagaag tgttgccaac
    24841 atgagtacca ccacaaagtt caatagagta gtcaccgata gtcacgacac gaacttcctt
    24901 gccgtatttc tcaccaaaga gggccatagc tcccatttct ttagcagtgt caatatccgt
    24961 ttcaactgtc ttcacttcaa gtgcttccca aattttctcg ttaacttgct gttcaatcgc
    25021 acgaagttcc tcagcagtta ctgcttggaa gtgggtaaag tcaaagcgaa ggaattcaac
    25081 ttcgttaaga gatcctgcct gtgttgcgtg gtttccaagg atattgtgaa gggcagcgtg
    25141 aagcaaatga gtcgcagtgt ggtttttcat gacacggtga cggcgattgc tatcaattac
    25201 caaggtatat tcttggttca aggcaagcgg tgcaaggact tcaactgtat gaagggcttg
    25261 accatttggg gctttctgaa cattggtcac agtagccaca accttacctg actcatccaa
    25321 gatttgtccg tagtcagcta cctgtccacc catttcagca taaaatgacg tttccgcaaa
    25381 gataagagag gcagttcctt ctgaaacagc ttctacttct gcattgtccg ccacgatagc
    25441 taccaattta gaagacaatt ggctagcatt gtagttgaag acactttcta cagtgatgtt
    25501 ttgaagagtt tcattttgca tacccattga gccacccttg acagctgagg cacgcgcgcg
    25561 ttcttgctgt tctttcatgg ctgcttcaaa accttcacgg tctacagtca taccagcttc
    25621 ttcagcgatt tcttcagtca attcaactgg gaacccataa gtatcataga gtttgaagac
    25681 atctgaacca gcgataacag attgaccttt ttctttcaag tctgctacaa tgccttgggc
    25741 aaagtgttga cctgagtgaa gggtacgggc aaatgattct tcttcgctct taacgatttt
    25801 ctcaataaag tcacgtttct caagcacttc tgggtagtag ctttccatga tttttccaac
    25861 agttggaacc aatttgtaaa ggaaaggttc gttgataccc aatttttgac catgcataga
    25921 agcacgacgg agaagacgac gaagaacata accacgacct tcatttcctg gaagggcacc
    25981 atcaccgata gcaaatgaaa gagaacgaat gtggtctgcg ataaccttga agctcatgtt
    26041 gtcgccatct tggtcataaa ccttaccaga caatttctcg acttcacgga taatcggcat
    26101 gaagaggtcc gtttcaaagt tggtcttagc cccttggata acagccacca aacgctccaa
    26161 accagcgccc gtatcaatgt tcttatgtgg caattccttg tattcgctac gaggaacagc
    26221 agggtctgcg ttaaattgtg acaaaacgat gttccagatt tcaatataac ggtcgttttc
    26281 aatatcttct gcaagcaggc gaagaccgat attttctggg tcaaaggctt ccccacggtc
    26341 aaagaagatt tctgtatctg gtccagaagg tcccgcaccg atttcccaga agttgtcctc
    26401 aattggaatc aagtgacttg gatccactcc cacttcaatc cagcggttgt aagaatcttt
    26461 atcgtctgga tagtaggtca tgtaaagttt ttcagcaggg aaatcaaacc attcagggct
    26521 tgtcaaaagc tcataagccc aagtgatagc ttcgtcacgg aagtaatccc cgatagagaa
    26581 gttccccagc atttcaaaca tggtatggtg acgcgcggtc ttccctacgt tttcgatgtc
    26641 gttggtacgg atagcctttt gggcattggt aatacgtgga ttttcaggga taatggtccc
    26701 gtcaaagtat ttcttaaggg ttgctacccc agagttgatc cacaaaagag ttgggtcatt
    26761 tacaggaacc aaacttactg atggttctac tgagtgacct ttggtcgccc agaaatcaag
    26821 ccacatttgg cgtacttgtg cactagatag ttgtttcata ttgtctcctt attcacttgt
    26881 ttaatgtgat tggctttcca gcatttccac atagtcaatc gcgacacaga gggaaatgac
    26941 taggtctgca taagcgtctt caagaaccgt tacggtatag gtagaggtca gatggaagag
    27001 ttccttctta atttccgcaa tcaactgatc gcgatcatcc agcaatttga aattcaaatc
    27061 ccagatattg ccctcgatac gaagacctag attatcaaac tcatacttat ctcgccagaa
    27121 ggtcaacttc ttacgaatga caaaactcga gccatcccga agctgaatct caaaacgagg
    27181 aagcaaggtc aagatttctt tactgatctg actgacttgt tcaccagccg catcatagat
    27241 ggtaaaagtt ttgggaatct taaaaaatga tccctccacc tgataggcaa tttctcccct
    27301 gtcatccttg atagcgaagc gttcgcctcc aagacgaaac ttttgtttga caagaaatgt
    27361 tttcatcaac acctccaaaa atcaaaagac aagctcatat cacgaagggc gaaaaaccgc
    27421 ggtaccacct tcattcaatg aacttgtcat tctcttgttc ttatgcaatt gtatgattga
    27481 gtagcatgac ttcctagctt agatggctcg cagcaccgcc atttctctgg actaagacaa
    27541 gtgaaaatca attctcaact ttcttattat aacgtttttt taagcttgcg tcaactggaa
    27601 atgatctccg ttgaattaga ccaattccct acatctctga ttactttttc aggatatatt
    27661 ttttcttact gccatttttc tttttatccc aaattttcat attactaaac acagctacta
    27721 gaatatttcc aaatataaag gtgcctatca cccaatatat ggactcagtt gttaggtatt
    27781 gtcgatccaa gccatccttt aaatggaata gtatagcagt ttggttaaca atcataaagg
    27841 ttggccagaa actttttttg aaaaaagtag acattttcat tatttgttgc cgctttctgt
    27901 aaggttaata ctcaataaaa atcaaaaagc aaactaggaa gctagcctca agctgtactt
    27961 gagtacggca aggcaacgct gacgtggttt gaagagtata ggcttagtat actactaggc
    28021 aagcaaataa gcaaataaac aaataaacaa ctagaataga aaaagatagg gctctaaaaa
    28081 ctgacttcta ttccttaaaa acgaaccagc ttgactgatt cgtcttctta cgtttatctc
    28141 ctacttccga tacattttaa actgtaggaa gaggtcgcta tatttccctg tccatttatg
    28201 gtcaaatttc tcataaactt ctaggtgttt catggtttca acatcgggat agaaggcctt
    28261 atcttccttt gtttcctctg ggagcaattc cttcgctggt aggtttggtg ttgaatagcc
    28321 gacatactcc gcattttgga gagcattttc aggtttcaac ataaagttga taaaggcata
    28381 ggctgagttt tggtttttaa ctgttttggg aatgaccata ttgtcaaacc aaagattgct
    28441 ggcctctgtc ggtaccacat aacgtagatt ttcatttttt tctaacattt ggctggcttc
    28501 accagagaag gtcacgccga ttgcaacatt attctgaatc atatagccct tcatctcgtc
    28561 cgcaacgata gccttgatat ttggagtcag tttgtagagc ttatccactg tctcttccaa
    28621 ctgctgcaga tccttggagt tgaggctgta gccgagggaa ttgagtccta gtcccagcac
    28681 ctcacgcgcc ccatcaaaga gcatgataga attcttatac tccggcttcc aaaggtcatc
    28741 ccaatgctca ggcgcttcat ctaccatggt ttcgttgtag acaattccta aggttcccca
    28801 gaagtaaggg atggagaatt tattacctgg gtcaaaggac tggttgagaa actctggtcc
    28861 gatattttcg attcctttaa tttttgaata atcaagcgga accaagaggt cttcgtcctt
    28921 catcttgtta atcatgtatt cacttggaat ggcaatatcg taggtcgttc caccctgctt
    28981 tatcttagtg tacatggctt cgttggagtc aaaagtctcg tactgaactt gaattcctgt
    29041 ttcttctgta aactgagtca agagttcagg atcgatatag tctccccagt tatagataac
    29101 caatttttga ctatctcgac tattgatttt actatctaaa tgagtcgcaa ttccccacaa
    29161 gacaaggata atcgctgcaa ttcctgctaa aaatgaatag atttttttca tgcttgctcc
    29221 tccttctcac gagagataaa gtaataacct acaactagga taatactaaa gagaaagact
    29281 agagcagaca gggcattgat ttctaaggaa atccccttgc gagcacgaga gtaaatctcg
    29341 actgataggg ttgaaaagcc atttcctgtt acaaagaagg tcacggcaaa atcatccagc
    29401 gaataggtga aggccatgaa gtaacctgca atgatagacg gagtcaggta aggaagcatg
    29461 atttccttaa acatctgaaa ttgactagct cccaagtcat aggccgcatg aatcatgtcg
    29521 ccattcattt ccttgagtcg aggcaagacc atcaagacca cgataggaat ggagaaggcc
    29581 acgtgactag atagaacggt caaaaagcca agtgaaaact tgagttgggt aaagagaatc
    29641 aagaagctag caccaatcat aacgtcaggc gcaaccatga ggatattatt gagtgataga
    29701 aaggcttctt ggtatttctt acgagactgg tagatgtaaa tggcaccaaa agtcccgata
    29761 atggtcgcta tcaaggctga taggaaggcc aagaaaaatg tctgagccaa aatcagcatg
    29821 agtctcccat ctccaaacat ggtttcaaag tgagtccagc taaaacctgt aaagctattc
    29881 atatcatcac cagcattaaa ggcatagcca atcaagtaaa aaatcggcag gtagaggacc
    29941 agaaagacca gtcccagata aaggttggca aattttttca tcgttctctc ctttccttgg
    30001 tcacccacat ggtgatgaac atggtcagga tgagaatcac accgatggtt gaacccatac
    30061 catagttgtc attggttaga aaattctgct caatagccgt ccccaaggtg ataacgcggt
    30121 tcccaccaat caaacgggtc agcatgaaga gactcaaact tgggataaag accgactgaa
    30181 ccccacttcg cacaccgttc atagatagag ggaagatgac atgacggaag gtctcccact
    30241 tagttgcacc aaggtcgtaa ctagcattga tgagattatt atccatatcg tctaagacat
    30301 tgaaaatcgg caaaatcata aaggggagct cgatgtagct tgcgacaaag ataaaggaaa
    30361 aatcggtaaa aagcaactgt tgtgaaccaa ttccgataaa ttccaagaat tggttaatag
    30421 agccattttg accaaaaatc ccgataaaag cataggcttt aaggagcaaa ttgatccagg
    30481 taggaaggat aatcagcatg agccagagtt gacggtgctt gagacgggtc aaaaagaggg
    30541 ctgttggata gctgataagc aaggtcacaa aggtcacaat ccctgcataa agcactgagt
    30601 tgaaactcat tttgaggtag gtcaagtttt gtgacgcaaa gtaagattta taattttcta
    30661 aactaaactg gccttcaatg ttgaaaaagg attgtccgaa aatcaagacc aagggtgcca
    30721 atacaaagag ggcaatccaa agcatgtagg gcactacaaa gagtttagag cttgttttct
    30781 tcatctcttt cctcctcgat cgcattgatc agacctgctt cttgctcttc gatttccacg
    30841 tattcttcga tacgagcatc gaactcttct tcggtttcat tgagacgcat gatgtggatg
    30901 tcttctgatt caaagtccag accgatttcc tcacccacga tggccttacg ggttgagtgg
    30961 atcatccatt catttccaag ttcgtcatag gcgataattt cataatgaac tccacggaag
    31021 agctgggtgt cgaccttaac ttggagtttg ccttcttcag gaagggtaat gcgcaagtcc
    31081 tctggacgaa taacgacctc aacaggttca tttggcttca tcccaccatc aaccgcttca
    31141 aagcgtttgc cgttaaattc gaccaagtag tcctcaatca tggtacctgg caagatgttt
    31201 gactccccga taaaggtggc aacaaagtgg ttgattggct catcgtagat gtccacaggg
    31261 gttccagact ggacaatctc gccatcattc ataacgaaaa tccagtcact catggcaaga
    31321 gcttcttcct gatcgtgagt gacaaagaca aaggtaatgc ccaatcgttg ttgtaattca
    31381 cgcaattcgt actgcatgtc tgttctcaat ttcaagtcca gcgctgataa aggctcgtcc
    31441 aacaagacca cacggggttg gttgatgata gcacgggcga tggccacacg ctgacgttgt
    31501 cctccagaaa gtttgcggat ggaacgtttt tcataacctt ccaactgaac catcttgaga
    31561 acttccgcta cacgctgctc gatttctttc ttatcaattt tacgcaagcg aagtggaaag
    31621 gcaacatttt caaacacatt catatgtggg aacaaggcat aggattggaa gacggtatgt
    31681 acgtcgcgct tgttggttgg aatatcattg atacgaacac cgtctagcat gatatctcct
    31741 gtcgtcgcat ccagtaaacc tgcaataatg tttaggatag ttgatttccc cgaaccagat
    31801 gcacctagaa gggtgtagaa tttcccttct tccaactcaa agttgatgtc tttgagaacc
    31861 ttggtgttgc tgtcttcaaa aactttagag acgtttttga attcgataat tggttttttc
    31921 aattggcata aattccttct ttttcataga ttaaccgatc ggggctctgt caggtcccca
    31981 ctacctcttg cagggagtaa aaccacctgc atacatcttc gctaccgata ggctttcacc
    32041 ccctttccat gacatagcag cagcttttca aatacagctt cctacttgct ttcacccaag
    32101 atccggactt ctctttcaag cgtaatacct gagtgttcct tgactttttc gataaccgat
    32161 tggatcaagt cctcgtagtc tttggccgtt ccatctgcga cattgatcat aaatcctgca
    32221 tgcttttctg acacttctac gccaccgata cgatagcctt tcaagccagc ttctgaaatt
    32281 aactgacctg caaaatgccc gactggacgc ttaaagaccg agccacaaga tgggtattcc
    32341 aaaggttgct tgagttcacg taggtgcgtc aagcggtcca tttcctgctt gataacctga
    32401 tgggttcctg gggctagggc aaatttaact gacaagacaa ctgcaccaga ctcctgaata
    32461 gctgaatggc ggtaaccaaa agccaagtct ttagcagaca gggtttcgat ttctccatcc
    32521 ttggtcaaga ccttacaaga ctgcaagatg tgagcaatct cgccaccata ggcacccgca
    32581 ttcataaaga cagcaccgcc aacgcttcct ggaataccac aagcaaactc aaagccagtc
    32641 aaactatgac ggagggcaat gcgagttgtt tcaatcaagt tagccccagc ttctgcttca
    32701 atggtatagc catcaacaga aacgttattg agcttgtcac acaagatgac aaatccacga
    32761 atcccaccat cacgaacgat gatattgctt gcattgccaa gaaccatcca agggatattt
    32821 tcttggttgg caaatttcac aaggcgcgcc aactcaaaac gatttcgtgg aaagaccaaa
    32881 taatcagcct ctccacctac ttttgtataa ctatagctat gcaagggttc cttaaaacgg
    32941 atatcaattc cttctaagat ttcaagcatt ttttctctta cagacatgtc actcttcctt
    33001 ttacaaaatt cattccatta taccattttt agagacattt gacgaccata aaaatacctt
    33061 gtttggattt tgcataagaa aaagaggttc cccccttttt atgatttttt acaaaagatt
    33121 tccttggttc cataggcgac cagaacgagc tccagtgcta gaatcacttc aaccaagact
    33181 ggatttgtca accagcctac ttggaaaaga gatggtgcca gatcaaagaa ggcatgcaag
    33241 ccataggctg ctaggagata aatccatttc ttctggcgaa cagcttggta aacccaaact
    33301 gtcaaaagta attggaaacc aagcgccaag attcgctcaa aaccaagcaa ataaatctgc
    33361 cagaccgaaa gtgactgaat ggtttttaac atattttcag acagtaattg cataacctgt
    33421 ggattctgag tttgaactgc cgaaagaacg atgtaaagat tgagtaaact aataaggcct
    33481 agaaaaatca actccaagcc actaggccat aggccaaggc atctgccttt tccaaacttc
    33541 tctttttctc caaccatttg aagaaaacaa gacgagccgt ttcctcaaaa aatgctgcca
    33601 tggctaggcc atagataata tagataagcg gatgatcttg caagagggca atactaccgt
    33661 ctttttgagg atgcaaaatc aagatatgca ccagtttttc caaaatctgc gaagagacaa
    33721 agaaagcgac tgcacccaag cccaagacag ctagattaat ctggtatttc tttttggtaa
    33781 accaaatgct tcctatcaga aaagctagca acagcaacat ggtaataatg atatgaatgg
    33841 tcattttctt ctcctattct gccttttcaa tatctttttt catctcgtca acattgaact
    33901 tagcaaacaa gtattgacgg tcttggactg ggaaacgttg gtccaactgg tcaactgctc
    33961 ccacctcgat aatgccttcc ttgatgacaa aatccatgac atgtccaccg aaggtcaaat
    34021 catctgatat gaagtgcaga tggtagcctg ccacactgac cccatggaaa atctgaggcg
    34081 tccagaaacc aacaatagtc cccgcaacat tgtcacgact atattccggt tgatgggttg
    34141 cgatatcagc aaacttggta tcgggtgttg acttaggaat catacgcaca tgcatatgtg
    34201 aaaattcccc ccgaatcttg atagagcgga aaagattttc cccatcataa taagactcaa
    34261 ttcgttcttt caattccttg tctgtcatct caaagcgctg gcggaaaatg acctctgcct
    34321 gatgcggtac cactgcagcg taaggaataa gggcatctgg tgacacttcc acaatttctg
    34381 gctggtctcc tgactctttg gcctgataag ccttgccatc caagacaatc aattccccat
    34441 caatggaatc caaggttccc aaaccaaggt caccatgttc tagcaattct cctactgtca
    34501 tagtaccacc ataaaggcca gccatcaagg ctccaagagt attgtattga aataatttca
    34561 ctggttcctg cacgttctta tccattcact ttcttgtctg ttattctata aatcttactc
    34621 ctaagtatac cacatttgcc cctagatgtg aacgagagaa acgctctaga cattgccaag
    34681 aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg tctggaatga agaaacaaag
    34741 caagtacaaa gaggtcgttt cctatctgaa aaatggtatc gagtctggac gatttccgac
    34801 gggtagtcgc ctgccttcta tccgtcaact gagccttgac tttcactgca gcaaggacac
    34861 cattcaacga gccctgctgg aattacggca cgaacaatac ctctatgcca agcctcagag
    34921 tggctactat gtattagaac aagggcaaca tcaagaccta gaaatcgagg ttaccgacga
    34981 acatgccagt gcctatgacg atttccgact ctgtgtcaat gaaaccttga ttggccgaga
    35041 aaactacctc ttcaactact atgacaatca agaaggatta gaagacctaa gacaatccat
    35101 tcacaaactc ctctttgacc aagctctcta ctgcaaggct aaccaactag tactgacttc
    35161 tggaacccaa caagccttgt ttatcctctc tcaaatatcc tttcctagcc aagccaagga
    35221 aatcttggtg gaacagccaa cctaccatcg gatgaatcgc ctcttgattg cacaggggct
    35281 ggactatcaa acgattgaac gaggcattga tgggattgac ttggaggagc tggaaggcca
    35341 cttcaaaaca ggaaaaatta agtttttcta caccattcct cgatttcact atcccctagg
    35401 ccattcctat tctgagcagg acaaacgagc tattcttgac ttagcagcca aatatagtgt
    35461 ttatatcgtc gaagacgact atctggggga tttggactct aaaaagggcc agaccttcca
    35521 ctatctagat acagaggaac gcgtcattta tatcaaatcc ttctcaacca gcctctttcc
    35581 agccttgcgg ataacagcac tcattcttcc aaatactatc aaagaagcct tcgtggccta
    35641 caaaaatatc ctagactacg acagcaacct catcatgcaa aaggccctgt cactctatat
    35701 tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg accaatcatg aatcttacca
    35761 aaaacaaatc gaggaaagga taactaaaac accttgtccc cttcctcatt atcccctaca
    35821 cgatggttta ttgctagacc tgagacagta tcctaaaatc gccagtctca aacacagtca
    35881 actgggcttg gacttctttg aagaggccta tttaagcacc tgtccttatc aatttgccaa
    35941 ggtgtcccta gacaatctgg aaaatgtttt aaactattta aaagcagaat tggaatgaca
    36001 tccaactctg ctttttctta ttcttcaact tcagttaaac ttgctgcttt ttcaagatag
    36061 ctttggtaag ttccttcatc cttaagtttt tggatgacct tgtctaccac ttctttcaaa
    36121 tcatcactat tttttctaag agcaacgaca ttggcgtcgc cgtccttcat cttcaagctg
    36181 acagttgcga cagctaagcc agcgttttta gcagcataac taagtgcaac aggctcatcc
    36241 atatgaacag catctatttt tccagcctgc aattcattga ctgcttcacc catattagtt
    36301 agggaagtta attgagcttt tggcaattgt tccttgacca ttgattctgg aacagtccct
    36361 ttttgggctg caatattagc actttctagg ctagttaaat ccttgtattt ttccacatca
    36421 gccttacgaa ccaagaaact aatcttgttt tcatagtatg ggattgaaaa atcaaagact
    36481 tcttttctct cgtcagtagc actaattcct gcaactgcta ggtcagcctt accagtttga
    36541 agactggtca aaacattgtc aaaactcatg cttaagattt ccaacttaac cccaagttca
    36601 tcagcgatag cctgagccat gtcgatgtct gcaccgacta cctggttctt tccatcaacc
    36661 aatgattgaa attcaaaggg tgcatagtca ggactggttg ccacaactaa tttccccttt
    36721 tgcttaatgg cctcaacagc tgactgagaa ccattggaac ctgactggca agctactaag
    36781 aagaaacttg caagaaactt gcaagaaaat tacataaaac aaatatccat ttttttgatt
    36841 tcataaataa acaacctttc tgttaatttt gtataattat aacgatatcc aagttacttg
    36901 tcaagtgttt tttaaatttt tatctcaaaa atattttttc gttcaaaaaa aggagccatc
    36961 agttgatttc aagctccttt ttatacagaa ttaaactatt ttatagttcg acaatcttac
    37021 ctgtttcaaa gtagacaacc cattcacaga tatttttagc ataatcaccg atacgctcca
    37081 agtaggaaat aacttggaaa taatcacgac ccgtaacaat ggcttctgga tttttcttaa
    37141 tctcttcagt cgcaaggtca cggatagttt caaaatagtg gttaatttgc tcatccatgg
    37201 aggccacccg gtatgcgtcg tcaacagaac cattaagata aagatcaagt gctgcttcaa
    37261 caacgctttt aacttcacgt cccatttttt taatttcttc ctctacagct gggatgcgtt
    37321 cttccccctt catacggatg gttgcctggg caatggctac agcgtgatcc cccatacgct
    37381 ccacatctga tacagcctta aggacagtca agactgtacg caaatcttga gagactggtt
    37441 gttggagtgc gatcatttca aatgatttct tttccagttt cacttcgtat tcatttactt
    37501 ctgcatcatc ttctatgacc tcttttgcca ggtcacggtc atgcgtgaca aaagcacgta
    37561 ccgtacgatt gatttgtgag agcacttctt gtcccatagc gtagaactgg ttatgtaatt
    37621 tctctaaatc ttcttcaaat tgagatcgta acatctttca tctccttatc caaattttcc
    37681 tgtaatatag tcttccgttt ccttgtgttg gggatcaagg aacatctgct tggtatcatt
    37741 aaattcaatc aaatctccat ctaggaaaaa tcctgtctta tcagagatac gtgaagcttg
    37801 ctgcatggaa cgggttacca gaagcatggt gtacttgtct tttagaccat acaaggtttc
    37861 ctcaatttta ccagctgaaa tcggatccaa agccgaagtt ggctcatcca agaggatgat
    37921 tttaggacta gttgccaaga cacgggccac gcagacacgc tgctgttgac cacctgacaa
    37981 tccaatagct gaatcatata gacgatcctt gacctcatcc cagatagagg caccttgcaa
    38041 ggctttttct acggcttcat ccagaacctg cttatcctta attccattga tacgaagccc
    38101 gtagacaaca ttctcataga tagtcatagg gaaaggatta ggttgttgga aaaccattcc
    38161 gatttcctta cgtaattcaa ccgtatctgt acgcggactg tagatgttgt gaccattgta
    38221 caccacggat ccagttgtgg tcacctctgg attgagatct cccatgcggt tgagagactt
    38281 gaggagggtt gacttccctg atccagatgg accaatcaag gctgtaattt ccttaggttg
    38341 gaaagatagg gaaacactat tcaaagcctt ctttttatta taataaacgg acaggtctga
    38401 tacctgtaaa atcgcatctg tcatacggtt tcctttctaa ccaaagtgac cagatacata
    38461 gtcattggtg gactgtagct tggcattttg gaaaatagtt gcagtcttat catactcaat
    38521 caaatcaccc aagtaaaaga agcctgtata gtcacttgca cgagcagcct gctgcatatt
    38581 atgcgttaca atgatgatgg taaagttttt cttgagctca aacatggtct cttctagttg
    38641 catggtcgca atcggatcca aggctgaggc tggctcatcc attaagagga tatctggctt
    38701 aacagagatg gcacgagcga tacagagacg ttgttgctga ccacctgata aggtcaaggc
    38761 tgacttgtgg agatcgtctt taacctgatc ccagagggca gcctgacgaa gggaggtttc
    38821 tacgatttca tctaggactt gcttatcctt aactccagca cgttcatgcg caaaggtgat
    38881 attacggtaa attgacttag caaatggatt ggggcgttga aaaaccattc caatgtgttt
    38941 acgcatttca taaacgttga tttctggacg gttgacatca attccacgat agagaatctg
    39001 cccagttact ttagcaatat caatagtatc attcatgcga ttgagactgc gtaagtaggt
    39061 agatttcccc gaccccgacg gaccaatcaa agctgtaatt ttatttcttt caaattgcat
    39121 atcaatcccc ttaatggatt catttttacc atagtaaaca tggacatcct tagtagaaag
    39181 ggctactttt tcttcaggaa aggtaaggat atgcttctca tcccagttat atgttgacat
    39241 ggcttctcct ttaggcagcg gttaatttct tgtgtagata gcttccgaac ttacgagctc
    39301 caaagttaaa aatcaggata aagatcagga gcacagcggc agaacctgct gatacaatgg
    39361 ttccatctgg aatagtgcct tcactattga ctttccagat atggacagcc aaggtttctg
    39421 cttgacggaa gatagagatg gggctagtca cactgaggat attccagtta gaccagtcaa
    39481 gagctggcgc cgattgccct gctgtataga tcagagctgc agcttcgcca aagatacgac
    39541 cagatgccaa gacgacaccc gttacaatac ctggaagcgc ttctggaata acaacatgaa
    39601 ccactgtctc ccagcgagaa atcccaagag ccagaccagc ctcacgttgg gtatggtgaa
    39661 cgtgtttcaa actatcctct acattacgcg tcatctgagg caaattaaag actgtcaagg
    39721 ccaaggcacc tgaaatgatt gaaaatccat actcaaactg gactacaaag atcaagtaac
    39781 caaagagacc caccaccact gatggtaaag aggacaagat ttcaatacaa gtccgcacaa
    39841 agttggtaac aggacctttt ttagcatatt cagccaagta aatcccagct cccatagaaa
    39901 gaggtacaga aataatcaag gtaatgacca ataggaaaaa ggaattgtaa agctgaatgc
    39961 caatcccacc acctgcttga aaagcagaag accttccagt caagaaagac caagagatat
    40021 ggggcaagcc ccgaaccaag atatagagaa tcaaggaagc caagattgtc acaatgatgc
    40081 tagcaatcgt atagaggaca gctgttgcaa gtttatctaa tttcttagcg cgcataattt
    40141 ttctttcctc tttctttcgt aatcaattta atcacactgt taaaaactaa actcatcaag
    40201 agcagtacca aggccagtga ccagagaaca ttattattta cagttcccat gacagtgttc
    40261 ccaattccca tagttaatat agaagttaaa gttgcagctg gtgtggtcaa ggaagttggg
    40321 ataacagctg agtttccgac aaccatctgg atagctaaag cctcaccaaa ggcacgcgcc
    40381 atcccaaaga ccactgcagt gaaaatacca gaacgggccg ccttcaagat cacacgccag
    40441 atagtctgcc agcgagtggc tcccatagcg aaacttgcct cacgataata acgaggaacc
    40501 gcacgcaagc tatccgttgt cataaaggtt acggtcggca aaatcatgac aaagaggacg
    40561 gaaatccctg acaaaatccc aaaaccagtc ccaccaaaga cactgcgaac aaagggaacg
    40621 acgacttgca agccaataaa tccgtacact actgaaggaa tcccaaccag gagttcaata
    40681 gctggttgca aaatcttcgc cccttttggt gatacttcgg tcataaaaac tgctgcacca
    40741 atagcaaagg gtgttgcgat aagggctgag agaatggtaa cgataaagga acccaaaatc
    40801 ataggaaggg caccaaattc tttactagaa ggattccaag ttcctcccaa aagaaagtca
    40861 aagatattca caccattgac aaagaaggtc gacaagcctt tttgcgctac gaaaaccaaa
    40921 atcatggcca caaggatgac tatcaaagaa agacaggcaa aggtcaaacc ttttcctaat
    40981 ttctccagac gagaattctt tgatggaagc aacattttct tagctaattc ttcttgattc
    41041 attattgtct cccttccaac actgtcacag ttccggcagc atctttttca accttcattt
    41101 ccttaatcgg aatatacttc aatcctttga caatcccttc ttgggtctca tccgagagaa
    41161 caaaattgag aaattctgca gctaactcat tgggctgccc caatgtatac atatgctcat
    41221 aagaccacaa gggccaatta ttgctactta tattttctgg acttaagtca tagccattca
    41281 acttcatgct tttgaccgaa tcatctatat aggtaagaga taaataagag atagctcctg
    41341 gactttttga tacgattgat tttaccgctc catttgaatc ctgctcctga ctttgcatgg
    41401 cagactgacc ttccataatg acagtatcaa aggtagcacg agagccagag ccggctgccc
    41461 gattgataac agagatgggt aagtccttac caccaacctc tttccaattg gttacctcac
    41521 ctatgaagat ttgacgaagt tgctctgtcg ttagattatc aacatcaacc tccttattga
    41581 caatcagagc caagccagct accgcgacct tgtggtcaac aagagcagaa gcatcaattc
    41641 cgtctttttc ctcagcaaat acatctgagt ttcctatatc aactgcccca gactgaacct
    41701 gggacaagcc tgtaccagaa cctccccctt ggacattgac cgtttttcca acatggatcg
    41761 tgccaaattc atctgccgct acttcaacca agggttgcaa ggcagttgag ccaacagccg
    41821 ttatggattc tccacgatca atccagctag cacagcctac taaacaagcc gtcagccaaa
    41881 aagcgataag agacagagca agcttttttc tttttttcac tgtttttctc ctcgaaaata
    41941 attatgaata ctgtgaattt tttaagtagt tctttatgag ttgacgcatg aattcttacc
    42001 aaatttctgc gcaattgatt atttatataa tataggctat attactcttt cctaacctcc
    42061 ttttttcata tgtggataaa atctcttgtc tatcccttcc cccattgtca cccattatag
    42121 tcatttcgtg tctctttttc ccctttttaa tgcaagggaa attactctcc ttagatgata
    42181 atctaaaagc tagaaaggta tctcaaatct ctctactctc ccagactagt ttacaactaa
    42241 aaggaaaaga ttctatttta tgagaaatct agtttacaag cggtaagaac gctaataact
    42301 aaacttcttg tactctttga aaatctcttc aaagcagtgt tttgagctat ctatggctag
    42361 cttcctagtt tgctctttga ttttcatcga gtagtaaaac tacatgtgat ggcaatcaag
    42421 atatcaagaa tcatcctact aaaaaaatcc atactttcac tataacatag aataagatat
    42481 ttgactagca ttttcatttg aatctgaggc cttttggaaa ataatttttc aaaacatttc
    42541 cagtaacctt tgcaaagccc aagccattgc ctttaaccaa aacttggtac caaccatttg
    42601 gcagactttc tgccagctga acggtttctc cagccgcata cttgacaaac tcttcttggc
    42661 caatttcaac cgactgttcg acctgactcg gtttcaaggc taaaccaaga gcgaaactgg
    42721 gctcaaagcg tttcttctta aaagtaccca gatgcagtcc attgcgagca atcttgagct
    42781 tccctaaatc tggcaaaagt tctggcaaga gataaagctg gtctccaaaa atctgcaaga
    42841 tacccggtag attgaccttc aaatggtttt gggcaaattc ctgccacaag gcaacttgtt
    42901 cacggctgag gttactctta cttgccttaa atttaggagc tggattgtta cccttaaact
    42961 gtagatgggc aacaaactga ccctctccct taaactgatg agggtacatc cgagccgttt
    43021 ctggcaggtc aataccagct accattccat tgatatgctc tactggcaac aagtcaaaat
    43081 catactcttc cagcaaccaa ttgacaatct cttcgttttc ctcgggtgcc caggtacagg
    43141 tcgaataaac cagacgacca ccttcagcta acatggtcac tgcatcctcc agaatttctc
    43201 tttgcaagct agcacattga ctcggataat ctaagctcca atagtccata gcatcaggtt
    43261 gcttacgaaa cattccttca ccagagcaag gggcatcaag aacgattaag tcaaaatagc
    43321 ctttaaagac cttgaccaag cggtcggcag attcattggt caccacgaca tttgtcgctc
    43381 caaaacgctc catgttttca accaaaatct tagcccgttt gcttgaaatt tcattggaaa
    43441 caagtagccc ctcccctgct agataggctg ccagttgagt tgatttgccc cccggtgcag
    43501 cagccaagtc caagaccttc ataccaggac tgggttgggc tacttgagcc accatttgag
    43561 cagcaggttc ttgcgaataa actaaacctg tagcatgctc aggcgatttc cctgaaacct
    43621 tcccatagtg gccccaaggg gtttgagtaa tggcatcaga aaaggaaagt tgctcttctt
    43681 ttaagggatt gacccgaaag gccgaaacca cttcctcctc aaaagaggca agaaaatctc
    43741 ttgcctcatc tcctagtatt tctttatatt tttcaacaaa tccttctgga aatttcattt
    43801 aagttctttt cctttcgtaa atataggact gaatttcctc ctgcatctca agaggcacca
    43861 tcatgaccgg ctgtctggtt tgaaaatcag gagcttcacc aaaaagggtc acaacccgat
    43921 agcccagact ttcccctaaa atactagctg cggcataatc ccatggttgc agataggtga
    43981 gataggtcaa caaacgccct gacaaaatct tggcaaaact aatggccgca cttccataga
    44041 cacgaacacc aagaaccgct cggctcaaat cagccagccc ccattcattg gtttccagca
    44101 taccactatt ccctgcaatg agaaaatctc caagtggttt agttttaaaa gaagctaggg
    44161 gcctatcatt tagacaaact ggaaattccc caccaccgtg gtaacaatcc cctttgacca
    44221 catcataaat cagaccaaac tgtccctgac cattttcaaa ataagccatc ataacagcaa
    44281 aatcttcctg ctgggctaca aaattattgg taccatcaat gggatcaatg acccaaacct
    44341 tgccctcttg aaccgaggct cgcagacaac cttcttcagc acaaatctta tcctcaggat
    44401 aacgggacaa aatctcacca accaagagtt cctgaacttc tttgtccagt ctggtcacca
    44461 aatctgttgg agaggacttg gtttcaacac gcaagtcttc ctgcatatgg tcaagaatgt
    44521 actgacctgc tttcttaaca agctctttag caaattcaaa tttactttcc aagagaaatc
    44581 tttccttccc ctttttcttt ggcagcctga actgctcggt aaagtgaata gccactaacc
    44641 gtttcaaatt ctcgtcccaa acgtttctct tcgctcttgc ttggcacgac cgctttgaat
    44701 cccttatagg agtccagtaa ctttttagcc tctactttgc cttcataggc agcttcaaca
    44761 tcattaaaaa aagaaagcac tgaagcaagt tcttcagtgc tccacgacaa atctagtggg
    44821 taactatact gtttgttcat taactaatac cagctctcat tcttgcttct tttagttctt
    44881 gcttacgata actacgaggg agaaaagcac gaatctcatc ttcattaaaa ccgatttgca
    44941 tacgcttggc atcaataata attggacgac gcaaaagact aggatactgc tcaatcaaat
    45001 gaagcaattc cgataccgaa atactctcta catcaatatt caatttttga aaaatttttg
    45061 aacgagttga aatgatgtca tcagtaccat tttcggtcaa ggaaaggatt tgttgcaatt
    45121 cttttcttgt taaaggactg gtcataatat tgtgttccac aaagggaacc ttatgttttt
    45181 ctaaccaggc cttagcctta cgacatgatg tacagctcgg tgatagaaat agtgtaatca
    45241 tgcttttctc ttcttatcta tactttgcta cttctattat acaaaaaaat aaggcgcttg
    45301 actagggatt tttagaaaaa aaagcctatt tttcaagaaa aataggctgt ttgcgaacga
    45361 ttgacacaat tggatttggt taattcactc ttaacgatgg ttttaaacga tatatatttt
    45421 tatatatgca aattaaaaac atctttcatt tcatttccta cgacttttca gacacagata
    45481 gccaaagaag ctttcataga gggcaaaaaa gaggaggaag gcatgaagaa agaaggtctc
    45541 tggcaaaatc ataataacag gatccttggc tggatcaaaa agccaggtat catctcccac
    45601 aaagagaatt tgatggaaaa gagtaaagaa ttggtcaaaa ccaatcaaaa ctcccccaag
    45661 tccaatcatc acaggtaaga ctactagagt caggagactt tttcgataaa gagacaaaaa
    45721 gtcctttttc acaattctat tgacaaagac atagaaactt ggcagtgtca ctagagctac
    45781 tagctgaacc aaatgaaaga gattcttgac cactgcgaaa tggtgcagac cagctgctga
    45841 cgaacgaaaa tcaggcatct gtaagacctg actaaaagga ttggtcagat aattcatcaa
    45901 gatatgaaaa ttgtattgaa tggtttctgg ttttagatag actcgattcg ttaagtttag
    45961 ccactgaatc tccataggat agaaaatcca agccagataa atggtcagaa ggattgagag
    46021 ggagaggaga aagagcatag agccccaaaa ggtcaattta gttttcatca aaatcccact
    46081 ccgcaaggct agaaaccaca tgtgtcggtg cgattggcag gccagctact tcttctgcct
    46141 tagtaaaacc tgtcgtcacc aagagcgttg gaatgccatt gtcaatccca gcccggatat
    46201 cagtcaaata attgtcccca accatgatta actcttcacg ttccaaacct aagtgctcaa
    46261 ccgccttgtc cataatgatg gcattgggtt ttccgatata aaccggcttc actcgtgtcg
    46321 ctacttcaag cagcgtaatc agtgagccag cacctggcaa aagaccgcgt tccgtcggga
    46381 tgttgaggtc aggattggtt ccgataaaat gggcaccctt ttgaatagca agagttgctg
    46441 tggcaaattt ttcatagtcg acttgccaat ccagaccaac taccacgtag gcagggtttt
    46501 ccttgtcttc cacataacca gccgccttga tggcttcctt gagtcctgct tctccgacga
    46561 catagacggt cttttcaagc cccaaatcat tcatatagtc gatggttgct aaagtcgctg
    46621 tgtagacagt cgataggggc gtatcgatat taaaattctg agccaacatc tccttaacac
    46681 tctctggagt gcgggttgta ttgttggtta caaagagata gggaatgtcc cgcttttgca
    46741 attcatgaac aaaagtctct ccagcaggga ttcggtcttt ccccttataa atggttccgt
    46801 ctaaatcaat taaatagcct ttatatttca tctatttctc cctaagcctt ttttatttct
    46861 tgccaagtaa tgattgcttg ggcattgata accccatcac ttgtaatttc atgcttgctt
    46921 tccagtccag tccgttcaac agccgatgta atcaccccac ctggtcgaac ttccttgaca
    46981 tacttgaggt tgattttctt gggaatatag tgggtcaaaa aatccgctcc catgacctca
    47041 aaaatccagt ccaagtattt actgttattg acatgaccat tcatatccaa gtcgtaaaaa
    47101 cgaacatggt aatccttgct gatcggctct tccaaggatt catacttcgg tccacggata
    47161 agttttttat caaaatcaga ctggtaagga gccacaatct caggttcaac aacatggact
    47221 tttcgactgt cgcggtccat gagaacaaag gtcgccatca tgtggatgag ctcctgcccc
    47281 gcttcattat aaatagtaaa gcgacggtag caaaaaagtc gattgtagct caaggcttcc
    47341 gtttcgatgg taatttcttc cgcaaaacga ggcaaacgaa ccacctcaat atcatattct
    47401 gcgataatcc agaccagatt atagtcttcc aaaatggcct tatcactaac tcccagttca
    47461 atcgattgca tccctgaaac ttgcagtgac agcaaaatca catctggaag tttgatatga
    47521 ccgttcatat cagccatatc aaaaggaatt ttcattttca tttgataagt taagcccatg
    47581 atcctactcc aaaataaatc gttctgctac agtatctccc aaaaagagac ctctctttgt
    47641 catgcgaacg tggtcaccct caatctgcat gaggccttgt tgaaccaagt ctctgacaat
    47701 ttctccataa agtccagcaa aagactgtcc aaatttttcc tcaaatcgcg ccatggaaac
    47761 cccggatttc ttgcggagtc ccaagaacat ttcttcttcc atttgctcct tttgactcag
    47821 gtgatcttct gtaatacaag cattgccttc ctcaaccgca ctgagataat gacgaatggg
    47881 accataattt ttataacgta ctccattgac ataaccagat gcccctgcac caataccata
    47941 gtattcagca ttgtcccagt acatgagatt atgacgactt tcaaagccgg gtttggagaa
    48001 attagaaatc tcataatgct caaaacccgc tcgctccagc tctgcaatga tgtactcaaa
    48061 catctccgct tctagttcct ccttaggcag aggcaatttc ccacgtcgca tccggttcat
    48121 aaagaccgta tggttttcta aaatcaaact atacaaactc atgtggggaa tatccaatcc
    48181 aatggcttta gccacatttt cctttacttg ctccatggtc tgaccaggca gagcataaat
    48241 caaatcaatg gagatgttgt caaaaccagc cagtttcagg cgatcgatat tttcataaat
    48301 atccttctcc aaatgactgc gcccaatctt tttcaacatc ttatcatcaa aggtctggac
    48361 acctagcgaa acacgattga cagccgaatt tttcaaaaca gctatcttat ccgcatccaa
    48421 atcgcctgga ttggcttcaa tggtcaactc ttccaagaca gacaaatcca agtttttagt
    48481 caagccattc agtaacacct ccagttgcgg agccgacagg gctgtcggtg ttccaccacc
    48541 gatataaagg gttgacaact tttcaatatc ataagaacga aactcttcca gcagatgctc
    48601 taaatagctg tcgactggct gatttttgat gaagaccttt gaaaaatcac aataataaca
    48661 aatctgggta caaaatggga tgtgcacata ggctgacgtt ggttttttct gcatagtaat
    48721 tattatacca caaagactag attccagata aaaatcacca tccccagata catagtccgt
    48781 tcggagatgg tgatggttta ttcttctgtt atatcaatca caatctcttc tgagtcatca
    48841 agagcttcgg ctttttcttg ccattgttcc ttgagattat ttaattgatt ttttgatgct
    48901 tctgtcgctt gaaaagcata ggatttagct tgagcaagta tactgtccac agtgatttca
    48961 cctgactcaa cctgttcttt tgttttcaga acaaaatctg tagcctgctc cttaacttct
    49021 gtcagttttt cacagacttg ctccttggca tactccggat cttctctcaa atcatctaga
    49081 aaatcttgag cctgactgca aacttgtttg cccttatcac ttgttaaaaa caaggcaaga
    49141 gctgcacctg aaacggttcc taaaaggatt gaggataatt tacccataag gattctcctt
    49201 ttttattttt tgaaaaattt acttgcaaga cgaagagctg acagacttgc accagtcttg
    49261 agtgtttttg aaccagctga tgaagctttc ttgctcaaga cacgcgcatg gtcattgagg
    49321 tctgaaacag atagagataa atctgcaaca gcactgaaga gtggatcaat cgtagccacc
    49381 ttgacattga tatcatctgc caagacattg accttagcca acaactcatt ggtatgatgc
    49441 aaggtcacat ccacatctga agtcaaggtt ttaatcgtct tttctgtttc atcgatgaca
    49501 cgaccaagct tttgtacagt aatgatcaga tagaccaaaa agacaatcaa agctagggca
    49561 acaagaatat atgcaacttc taacatttag ttttcctcct ctgtaatata gtaaggggcc
    49621 ttctttcgat tttgataaat aacgatcatt ataccgagac cgataaggac aactgacagc
    49681 cattgggaca ctcgaaggcc gaagaacatg agactatctg ttcgcatacc ttcgatgacc
    49741 atacgaccga aaccatacca aatcaagtaa aaggccgtga tatgacctcg tctgagactc
    49801 ttccatttcc gtctaaaaat cagaatcaag gcaaagccaa gcagattcca tagagactca
    49861 taaaggaaag tcggttgacg gtagctcccc tcaatataca tctggtcacg gataaagcca
    49921 ggtagataat caagattatc cactgttgca ccataagctt cttggttaaa gaaattaccc
    49981 caacgcccca aactttgagc aatcataacg ctaggcgccg caatatctag aaaatcccaa
    50041 gtattgatga gtttacggtc agcaaagata tagagcacaa gagccccagt tatcaaacca
    50101 ccgtaaatgg ccaaaccacc attccaaatg gcaaaaatct ctcctaaatt ctgactatag
    50161 taatcaaatc ggaaaataac atagtagaga cgagctccta aaatagccaa gggaaaggct
    50221 actaagataa aatctaaaat atcgtctggt atgatcttct ttctaggtgc ttctttcatg
    50281 gtcaaataaa ccgcaagaat caagcctgtc acaatacata aggcatacca acgaatggct
    50341 aggggtccta gttgaatagc aattggatca agcattttgc acctcatttc gagcgattag
    50401 acttgtcagt cgttcgtcga acaaacgggt cgcatcaaag cccatttcct tggcacgata
    50461 attcatggca gctgcctcaa tcacaacaga gatattacga cctgttttaa ctggaatacg
    50521 aatacgagga atggctacgc cagaaacttc aagttcctct gcattgtttc caagacgatc
    50581 aaaggtctta tgtgtatcgt aattttccaa atagacagca agctgaacct gtgaagaatc
    50641 cttgacagca ctcgcaccgt agagactcat aacatcgata ataccaaccc cacgaatttc
    50701 aatcaagtgt ttcaaaattt cagctggttc accccagaga gtaatctcat ccttggcaaa
    50761 gatatcgaca cggtcatcgg ctaccaaacg gtgaccacgt ttgacaagct caagacctgt
    50821 ctcgctctta ccaattccac tatctccctg aatcaagacg cccatcccat aaatatccat
    50881 caagacaccg tgcacactgg tacgttctgc caaacgagaa tccagatagc tagataactc
    50941 tccagataaa cgactggtag ctgcacggct ggttaaaata gcaatcttac attctctagc
    51001 agcctttaac atctcctctg gaaccaccaa accacgggca acaatgactg ctggtgtctc
    51061 aggtagaaac atttttttca aaacttcata acggctgttg gaaggcatgc tgatcagata
    51121 agaccactcc ttcatcccca aaagttgaat ccgctctggt gtatagtagt caaaatagcc
    51181 tgtcatttca agaccaggtc gcgtaatatc cgctatattg atttcctttt caagcaattc
    51241 tggttcacca tagacaatgt ctagtctaag cttttcaatc acttctttta ctaaaaccga
    51301 catcatttcc tccttcaaat gagttcttct ctctattata tcaaattgta ggaggaagtt
    51361 tcagattttt gcaggctttg gagtatttat ttaaaagaaa aaggactaga tttctctagc
    51421 ctttcattcc aattagaatt ttttacgttt acgagctact tctgatttac gtttacgttt
    51481 tacagaaggt ttttcataga attcacgttt gcgtgtttct tgaagagtac cagctttagt
    51541 aaccgcacgt ttgaaacggc gaagtgcgtc gtcaagagat tcattcttac gtactactgt
    51601 tttagacatt tttttcactc ccttcaagtt caatatctat ttcattctac acgtaaaagg
    51661 aataattgtc aagcaaaaat gcggtttaat tttgattttt tcttccattt atacaagagt
    51721 tgaaagcgtt caatagaaca ttgctttttt atttttcgag taagctaagc gcttcagcat
    51781 ctgcgatgat ggttacatca gggtgatttt ggaggctact tgcaggtagg ttctcagtca
    51841 ctgggccaga tactgttccg gcaatggctt ctgctttcga ctcaccgtaa gcaaaaagaa
    51901 taatagactt ggcatccaaa atgtttttaa tccccattga aatagcttgg gttgggacgt
    51961 cttcaatctt ggcaaagaag cgtgcattgg cttcaatagt agactggtca agttctacta
    52021 gatgcgtttg actgtcaaat ggagtaccag gctcattaaa gccgatatgc ccattgcgac
    52081 caattcccaa gatttggagg tcaactggat ggtcagccaa aatttggttg tagcgttcaa
    52141 cttcagcttc agcattgtcc ttaacaccac gaggcaagaa actttcttta aatggttttt
    52201 ggttgaacaa gttttcttgc atgaagtaac gataagactg tggattgtcc ccatcaaggc
    52261 ccacatactc atcaaggttg acactggtta gatttgaaaa atcaaggtca ctctcaacaa
    52321 tttccttgta aaattcaagt gggctacttc ctgtcgcaag tcctagagtt tgagctccat
    52381 tagccaattt ttccttcaaa atctcaaaag caacttttcc accttgaact tggttttcaa
    52441 ctttaataac tttcatcttt tcatcctcca tttctgtcta tatttattat atggtataga
    52501 ccaatttttg tcaagtgaaa acgatttaat ttctaaaaaa agagcgtcca aacttgaaac
    52561 gtgttataat ggataggatt ataacttaga aagaatgaac aaatatatga atacagctga
    52621 ttttgatttc cacttgccag aggaattgat tgcccaaacg ccccttgaaa aacgtgatgc
    52681 ctccaaactc ctcatcgtca accgtgagac aggagaaatg caagataaac atttccactc
    52741 tattattgat atgctggaac ctggtgatgc ccttgtcatg aacgacaccc gagttctccc
    52801 tgcccgcctc tatggtcaaa aaatggagac aggaggtcat gtggaacttc tcctccttaa
    52861 gaacactagt ggagacgagt gggaagttct ggctaaacct gccaaacgcc tcaaggtcgg
    52921 tactcgtatc agctttggtg atggccgcct cagcgctgtc gttacagaag aattgaccca
    52981 cgggggacgc attgtccgct ttgaatacca aggaattttc ctagaagtct tggaaagtct
    53041 gggagaaatg cctctgccac cttatatcca cgaaaaatta gatgaccgtg aacgttatca
    53101 aaccgtctac gccaaggaaa gcggctctgc tgcagcaccg actgctggtc ttcacttcac
    53161 caaagaactg ctggcagaaa tccaagctaa gggtgttcat ctagtctatc tgactctcca
    53221 tgtcggactc ggaaccttta gacctgtttc tgtggataat ctggacgaac acgaaatgca
    53281 ctcagagttc tatcaacttt ctgaggaagc tgctgccacc cttcgctctg tcaaagaaaa
    53341 tggtggtcgc gtcatcgctg tcggaaccac ttctatccgc accttggaaa ctattggttc
    53401 caagtttgat gggcaaatcc aagcagattc tggttggacc aatatcttta tcaaacctgg
    53461 gtatgagtgg aaggtcgtgg atgccttctc aaccaacttc catctgccaa aatcaactct
    53521 ggtcatgttg gtttctgcct ttgcaggccg tgaattagtc ttagatgcct accaccatgc
    53581 catccaagaa cactaccgct tcttcagttt tggtgacgcc atgtttattt attgagaaag
    53641 aatttctcta attcttctaa taccaataaa tcgctaagat attatttcaa agaacatcta
    53701 caattgaaac tctagctagc tgtagaagac gcctagtaca ttgaaattaa aatgcttccc
    53761 cctagcttcg aaaatattgc catagattgc gttgactctc caaattgatt catctatatt
    53821 ttatttcagc ttcctatatt ttcttcgctg tttgtaaatc aaaatgcaag acacatgagt
    53881 agcaccatat ttgttactct tatctgtcct ctcaagagac tattatgagt tatttcagaa
    53941 tcattcacta ctttgaccct gactctcctt agtctcaaaa tcaaagactt atactcttca
    54001 aaaatctctt caaaccgcgt caacgtcacc ttggattata tatgtgactg acttcgtcag
    54061 ttctatctac aacctcaaag cagtactttg agcaacctgc gactagtttt ctagtttgct
    54121 ctttgatttt cattgagtat taaacaaaaa gtgaacaaat ctgaattcta atgtacagaa
    54181 gactaggctt gttcactttt ttatagtcgc tataagatga ccttatctat agctttttat
    54241 atataattat atattcagac atactattat caattttgtc gcagggagga atctgttaac
    54301 gcacccattc accattatca ttgactctat agccatctat acttgtattg accgctaact
    54361 cacccgatgc atttacataa taccatttac caccaacttg gaaccattga ttgactttca
    54421 tagaaccgtt gctgttgagg tagtaccatg aaccattaac ttgtacccaa cctgttgcca
    54481 tggaaccatc agtattataa aaataccaca taccattttc ttgtttccag tctgttgttg
    54541 gagcaactgc tttagctggt tctactgcta catctgttcc ttggttagat gtaacagata
    54601 caggatacga aggaatagat gattgctcag gaacaacaac tttttcaggt tctctcgtcc
    54661 ctctccttat acgtcttttt accatctctt tagtaatttg acgagaagta gtttcttcaa
    54721 ttgttccatc acgttcatct acagtataga ttgtagtaag agtaatttac caatttctcc
    54781 tacttcttct acttcttgac ttttatcaag agttgggcca tcgagatatt ctgtttcgat
    54841 tggaatttct tggacaagaa cttggggctt ggttcttttt ttaacaactc ttgtttgaga
    54901 gtcttttttt gacttaaagt actctcagtt acttgtccac tctttccatc tacattataa
    54961 gttatcgttg taactgtttt cccattcttt cctagagtaa tctcttgctc ctgtcctgca
    55021 gaaaggtcat tgtctgcttc atatttagta gcaaatggaa caagaacttc ttcaaccttg
    55081 cttttagctg gaactttgat aactgtatcc gtggcttctt ttctatcaac agtaacctgt
    55141 tcggtaacat aaccagtctc tggattaaca tcgtaggtcc ttgtcgtagt tacatagcca
    55201 tcctctccat caattgtaac aggattttca ctacggtctt ttgtttcatc tttttcataa
    55261 cgaattcgcg tacttgaaat tttcttggtt actaccttag gtttagtcgc tacttttaca
    55321 ataatatccc cattgtcagc gtcatcatac tctattccct cttctttatc tctagtatca
    55381 tctctgacat attgaatccc atcagcagca tgaacaaaac ttgtattcag attcctccta
    55441 aaaataaagt tagcccgatt accgcagaac caaaaatctt tccgagttta cgtattgcat
    55501 agcgcttatt agtattagat tttgccatta catcctactt ctagtatagc atcttttcta
    55561 tcaaacgtta aacaatatac tttatatata aaatagactt agaatgatat attgattatt
    55621 gaactaacac tttaactata tcgtaatcaa tctcatatat aaaggattgc agacatctta
    55681 tctaaataca tgctaatata tttagataca aacattccaa cttgataatt ttcactcatc
    55741 tttcatcatt ccttatacaa ctatgcagta taaatagaat agttttctca tcagaatgag
    55801 actattttaa tattagataa tttgatagaa aaaacatgaa taaaattggt tgaatttaat
    55861 tccctaactc gatagaggat tctattttaa atttaacaac agctaggatt acactataaa
    55921 aagtacatta ccacctgttc ggctggagaa tctagtcgat tagctccctc ttagttacaa
    55981 gcttcaagcg attttttaac taacactaaa ccagattaaa gaaggaacta gaacatctgt
    56041 cttgtactaa tcaatatgct attttaaagt ttcaaataaa cttggaatgc taattattat
    56101 atttacaata aatagttgac ttcgatagaa acagaaaata gaattcaaca ttcttcccta
    56161 cttataccat aataaataag atccgcaaga tagccttttc tctctacacc attaacaatg
    56221 gtttgtagat aggacattcc agccttttcc atgacacgac ctgaagctgg gttgagactg
    56281 gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa aacaaaagtc caagatagct
    56341 ttcaaagtct ctgtcatcat accatttccc cagtaagcct tgcctaacac atagccaatt
    56401 tcacagctta aatcagcctc gtctatctta acaatgctga tatctcctat tacttgctct
    56461 gggttttctt ttagacaaat ggcccattta taatagttga gattagtata ggaagcaacc
    56521 caattgcaaa tcgagtttcg agtgatttcg acatcaggat ggggatccca ggtaacatag
    56581 gtcagattct cagcggatga agcccaattt tgaaacatgg cttctgcatc actctccaca
    56641 aatcttctta aaatcaaacg ttctgtctgt aatatttgcg taccgataga tttcatgatg
    56701 ctacctcact tccttatttc tatactcgta gtaaaaaggc tcaactcagt aacagctaga
    56761 aaacgagttt gtcttctaat ttcttgacgc agttgctgcc tggtttgaaa tgcgctctag
    56821 caagcttttt caaacctagt catcgttgca ggggtaagac gatgaaatcg aactcttcga
    56881 gttactgaat ctgcctcatt ttcttatttc taaactcggg gttcaagatc ccccagacct
    56941 tctctcactt tcttatttca agatgagagg ctgaaaacct ccagtggagg tttttcttgc
    57001 tttttaattt cagggcaaga agctaaaaag gtcccccgga cctttttact cccaaaagtc
    57061 atcaaatacg gtgatgggta agtggcgttt gtgttggcct ttgtgccacc agttttcaat
    57121 ggtcgcttga gcttctgggc tgattgtttt gccttctagg tagtcgtcaa tctctgcgta
    57181 ggtgactcca agtgcgactt cgtcagctag gcctggttta tcttcttcta ggtctgccgt
    57241 tgggattttt tcataaaggg ctggctctgc gccaagtttc tgcaagagct gttttccttg
    57301 gcgtttattg aggcggtaaa gagggagaat atccgcaccg ccgtcaccaa acttggtaaa
    57361 gaaacctgtg atattttccg cggcgtggtc tgttccaatg accgctccgc tatgggaacc
    57421 agcaagggca tactgagcaa tcatacggca acgtgccttg atattcccct tgttgaagtc
    57481 tgaaacagga ctacctgtcg cttcaactgc agctgtcatg gcatcagctg attccttgat
    57541 attcacaacc aagctgacat ctggctggat gaaggctagg gctttttgag catctgcttc
    57601 atcagcttgc actccgtatg gcaggcggac agcgataaat ttgtagctat cgtctcccgt
    57661 ttcagctcgc agttcttcca tagctaattg cgccaaacgt cctgccaagg ttgagtcttg
    57721 tcccccagaa atccctagta caaaggtttt taggaaggga tgttttttca gatatctttt
    57781 taagaaatca atagaacgac ggatttcttc ctgggcatca atcactggtt tgacacccag
    57841 ctcttggata atcgtttctt gcaaactcat tcttcttctc cttcaccaag ggcttccttg
    57901 cgcatcttat caatcaagtc catcttatct tgccatacat cacgcgccaa atccactgga
    57961 tagtgctgcg gattgagcac acgcttatac tcatcccaca acttgtcaaa ttccttacgg
    58021 gcataatcct gaatgtcagt caaactaggc aagttgtaaa ctaatattcc ttctttgaag
    58081 atatccacca agagaggaac ggcatcaaaa ttacgaaccg tcttcttgat gtatgtatag
    58141 gtcggatgga acatcttgat ttctgtcatg tcgctaatat ccacaccatc ataagtgata
    58201 tagtcgcctt ctgacttgcc tttttcacga ctggtaatgc gccacacctg cttcttacct
    58261 ggcgtagaaa ctttttcagc attattagac agcttaatcg tattgcgcat ctgaccagtt
    58321 tcatcttcga ttgcaacaat cttgtaaacc gccccaagag ccggctggtc ataggctgta
    58381 atcagcttgg tacccacacc ccagacatca atcttggcct tttgcatctt gaggttaagg
    58441 atggtatttt catctagatc attagaagca taaatcttag cctctgtaaa tccagcctca
    58501 tccagttgct gacggacttt cttagaaatg taggcaatat ccccagagtc aatccgcaca
    58561 cccataaagt taatctgatc acccagctca cgcgccacct gaatggcagc tggtacaccg
    58621 atgcgaaggg tgtcataggt atccacaaga aagacacaat ttttgtgggt cgcagcgtaa
    58681 gccttgaaag cttcatagtc attgccataa acctgtacca aggcatgggc atgggttccc
    58741 aaaacaggaa tgtcaaagag cttacccgca cgcacgttgc tagttccatt ggcgccacca
    58801 atcacagctg cgcgtgttcc ccagatggcc gcatccattt cttgagcccg acgtgtccca
    58861 aactccatca agggttcatc ttcgataacc gaacgaatac gagctgcctt cgtcgccacc
    58921 aaggtctggt agttgacgat gttcaaaaga gccgtttcga ccaactgaca ttgggctaga
    58981 ggtccttcca cctgcacaat cggttcatta gcaaaaacca aatccccttc ttgggcagaa
    59041 cgaacggtca actccaactt gaaattgcga aggtaatcca agaacgcccc atgataacca
    59101 agcgactcca aataggctat atcactatct gaaaaacgca agtcttcaag atagttcaca
    59161 attctttcca aacctgcaaa aaccgcatag ccgttcttaa aaggctgttg gcggaaatac
    59221 acctcaaaga ccgccttctt attgtgaatc ccttggtcaa agtaaacctg catcatgttg
    59281 atctggtaca agtccgtgtg caatgtcaaa ctatcatctg gatacatact tttcctactt
    59341 ccttagctag aaacccatga aaattttcaa gaactttcat gtattccaat aaattagtac
    59401 tattatatca cattttagct ggattgagaa aagagtaaca agctattctc cactctccaa
    59461 ttcatccata tcttgttcaa attttttctg agcccattcg ccatagctct taagaccaag
    59521 attgccaata aagatccacg gaaggtaaat gatataagta atgacccaag cagacaggta
    59581 tttaaaattc aaaggattgt gctgataaat ttctatgttg aattgataat tctgcaacat
    59641 caaaagagcc gtaatagcca aggttaggaa aaaacaaccc aaaatcgtaa aatgaaaacg
    59701 actatagtag gtcactccca gataacgggc acgattgaaa aagtaaaatg tccctatgat
    59761 gataacgatt agcagcatat tagaattaaa aaggcttggt gctaatactg aaatgatata
    59821 agataggagc gacaaagcga tgcagatata gaaactttca gagcccgctt tattgaacag
    59881 ttgttcttct ctttcgtcta gtaattgata ataataaaat ctatttttca tcttcttcct
    59941 cccaaaatag ttggtctagg gttttcccta aacatctgca aatggactgg cagagcgaga
    60001 gactgggatt gtatttcccc gcttctatca aaccaatagt ctggcgcgtc accccgacag
    60061 cctctgccag ttgaccttgt gttaaatcac gctctacccg agctaatttt aattttaaat
    60121 ttttagccac cttcgtcctc cttatagttt taatactcat ctactcttaa aaaatccaaa
    60181 accaacacaa gctatcagct atttattata accccattaa tttgcactcc agtattatct
    60241 tcagccgaaa atcagtattt taggttgttt gaaataaact tcctagttta ctcttttatt
    60301 tttatttagt attagcttta gtaggatctt ttaaacgagt ttttattgct tatatttctt
    60361 gtttagttta gttggtttca tatcactatt atataatgct tttggaaatg agcctagtat
    60421 aagtcaaaaa cgtgttgaat agtgaaagca ggagcatacc aagatgactg atttttttat
    60481 tgtattttag gtatgcaaaa taatactaaa tgaaactaaa atgaatactt cttgcttttc
    60541 ttgagagtga aaaagtacaa taaaatgatt gtagtgatta gcacaagata ctgactaata
    60601 gacatcgtat ttgaagccac aaatacaggt aaagaataaa aaaggaagaa gttcaattgc
    60661 tttgataaac aaatcattac tagtattcat catcatcgta tttaatatat tagagataaa
    60721 gagtagtaaa gctactaaaa taccaaatac caagccactt ttcaatttgt ataaatagaa
    60781 aatgtaagat aatagaaaat aaaacaggac taacaaaatt gtattgacta caatagctac
    60841 tataaaattt aatcctaaat cacctggaat acccaattta cttactatga ctagtaacac
    60901 aatgccattc aaagcataaa taatggaaac tgagatagca tatagaaaat tagacaagac
    60961 gtaaatcatc cgattcttct gtttatttaa tttcatgatt ataaccttcc tttattttga
    61021 acgatttagg taaatatctt taagcgtctc ttttttagtt tcaaaatcaa ctactttaat
    61081 agagttttcg ttaaaaaatt taaaaagctc actattttga atattcccag acatagtaat
    61141 tctcaatccc tcttcctaaa caatatccca aaattcttgt ttggtaatga aaatgtctct
    61201 atctgtagct gatgaaaaag ctatctcaaa caagaaatta tgactatctt ttcctacttt
    61261 ttgaaatgtc aaaagcccgt tctccaagaa aagaactctc tcacaaattt cttcaatgtc
    61321 ttctaattta tgactcgata ttaaaattcc cacattttca tgtaaagcta atttttttag
    61381 aaccgctaaa actatttgtg atgattcaat atctaaacca ttagtcggtt catctaaaat
    61441 caatatatca ggttccgtaa cgagagttag aagcaaagct aatttttgtt ttgtacccaa
    61501 agaataggtc tttacttttt tattaataga ctgagtcaaa tctaactctt ggatcaaaca
    61561 tctaaatctt tcttgattgt agtcaacacc atataaattt gacaaatatt ttaaattctc
    61621 taaacctgtt ttagataaaa ataattttgg ttcttcgatt aaatacccaa cattatcact
    61681 gcttataata ttacctgaag tcggttgatt attctgaaca agaattttca tcaacgtact
    61741 cttaccaact ccatttctcc ctgctagacc aacaatttca cccttgttaa gtgcaaaatt
    61801 tatatctttg agaatgattg aatgaccata atgcttactt acatttttta ttcctccatt
    61861 aatattattg gttttctctt tgattctcat taattttaaa aagttgcgcc tctttttaac
    61921 aatattatat catatatcta acttaatgca atatataaat gtcattttgt gaaattttat
    61981 taacaaaaaa ctctctacaa caaaataata gagagttttc tgcttattaa tttttttcaa
    62041 aatatctaag acatcacttc tttgtttaat ttgataggct ttgatacctg agctccgact
    62101 ttatcactta aaaaataaaa aagacagcta atctcttgcg catcaaggga tttcgccatt
    62161 ctttaatctc gtttaagtgt tgtatatgga gctttgcata attttttaaa actaaacaac
    62221 tacattaagc acgaactgtg acgctggttc catcttcctt ataaagattg ataagcccct
    62281 ctttaagagc tcgaaccatg tctccagctt gaacaggttg tgggacttta atagtcaata
    62341 gttccattgg atttggagcg cggtcgattt tattgccttt ggcctcatgc aaatcttcaa
    62401 tataggtttc aaaatgacgg aaacctggac cataaaactc aacttggtcc ccttcgttaa
    62461 tgacgttccg ttgacgaatg gttgctgttt gtgtcgcatc atcataagaa atcacttcag
    62521 cgacaaactt gtactcagga attttacgac gagcaccaaa caactgctca ttttcagatg
    62581 gtataccata gtaaaatcct gtagccagtt cacgttgggc aaccttccac atctcgtcca
    62641 ccaagtcttg tttgatagct tcaaactttt caggactttc aagataggca tccacagccg
    62701 ccttgtagca gttggttact gttgatacgt agtgaataga ctccactcca tacgtccttc
    62761 gatttttaga ttgtccacac cattttcaat catatctgga atgtggtcaa tcatagacat
    62821 gtcaacggct gacattgaaa attcttctgg aatctcaccc tgcaaactct tacgttcttt
    62881 cccaaatggc atatcgtaaa ggtcgtattt ccaacggcat gactgagaac atccaccacg
    62941 gttggcatca cgcatactct agacggattg ttttgacaat tctaatcttt tagactttgc
    63001 ataataactg ttaaacagtc gaaaattacc ccagttttaa caagtagtca aaataccaga
    63061 taaaggaaaa aagtctttaa aatcttaaaa acgcatagta tcaggtattg aacaatcttg
    63121 atattatgcg ttttattgtg ggaagattta cttcattttc tcttgaaatt gagttttctc
    63181 ctacttcaaa actagatgat ttgctattta aaatagcgtt ccttatgatt ttggcaacct
    63241 ggattaaagc gagaaaaaca aaaggggcaa cttaaacttt ctttatattg cttatatgtt
    63301 agtagtttta gacaaacacc acataaaata ggcttatcct gtatcaaaga taagggatac
    63361 ggctcaaaag ggtgattttc taatgaatca tgacaccgat aacaagcata atacttttta
    63421 caatcatagc attgtaaagc aataatatcc agcttgctat ggtaatgaat gcatcttgtt
    63481 tgcttatcca ctaagaaacc ctgtgcctct atcatttcct tttcctttct taagctcgaa
    63541 ctgtgacgct ggttccatct tccttataaa aattgatgag tccttctttt aatgcacgaa
    63601 ccatgtctcc agcttgaacg ggttgtggga ctttaatagt caatagttcc attggatttg
    63661 gagcgcggtc gattttattg cctttggcat catgcaaatc ttcaatatag gtttcaaaat
    63721 gacggaaacc tggaccataa aactcaactt ggtccccttc gttaatgacg tttcgttgac
    63781 gaatggttgc tgtttgtgtc gcatcatcat aagaaaccac ttcagcgaca aacttgtact
    63841 cagggatttt acggcgagca ccaaacaact gctcattttc agatggtata ccgtagtaga
    63901 aacctgttgc caattcacgt tgggcaacct tccacatctc gtccactaag tcttgtttga
    63961 tagcttcaaa cttttcagga ctttcaagat aggcatccac agccgccttg tagcagttgg
    64021 ttactgttga tacgtagtga atagacttca tacgtccttc gatttttaga ctgtccacac
    64081 cattttcaat catatctgga atgtggtcaa tcatagacat gtcaacggct gacattgaaa
    64141 attcttctgg aatctcaccc tgcaaactct tacgttcttt cccaaatggc atatcgtaaa
    64201 ggtcgtattt ccaacggcat gactgagaac atccaccacg gttggcatca cgcatactca
    64261 tgtggtttga aagagtacaa cgtccagagt atgaaataca catagctcca tggacaaagg
    64321 cttcaatttc aacatctgta cgtttgcgga tctcagctaa ttcttccatt gaaacctcac
    64381 gcgctaaaac gacacgagtc aagcctagct ctttccagaa ctcaagggtt tcatagttag
    64441 tggcactggc ttgggtagaa aggtggattt caaggcctgg tgcttcagtc gctgcaatca
    64501 taatcaaggc tgggtcagat acgataactg ctgcaatccc gatatcacgc agtttacgga
    64561 accactcacc agcaccagct tcatttcctt cgtgcataac catattagcc gctacataga
    64621 ccttggcacc atacttggcc gcaaactgca cgccttcttc catctgttcg aaagtaaagt
    64681 ttcccgcacg gctacgaaga ccataggcct gaccaccgat aaagacagca tctgctccat
    64741 actgaacagc tacctttagc ttctctaaag tccctgcagg tgataaaacc tcaggacgtt
    64801 ttaatgtttt tgtcatgatt tctcctattt gcaatataaa agtttgacat ttttccttct
    64861 cattttatag taaataaagg ataaaatcaa gcctagacgg attgttttga caattctaat
    64921 cttttagact ttgcataata actgttaaac agtcgaaaat tatcccagtt ttaacaagta
    64981 gtcaaaaagt ctagaaaagt aaaaaccagt atccaaagat actgactcgt aaaaatacat
    65041 aaattagtcc ttagatgact actcccactc tgttgctcct ataatggaaa aggattgata
    65101 cagtctagaa tatcgctttt ttatttatta ttctgatata aaactgttag aattgatttt
    65161 ttgttttata cccaaatatg aatagagacg tagctaataa gttgaataac atatttggaa
    65221 aaatgagaaa tagcaatatt actagaactt ttagaaacaa tcaatattta aaaagaaaaa
    65281 gctcaaagaa tttattaaac catgttataa tagatatagc tataatttta tttataacaa
    65341 gaggatagaa atgaccgaat tagaaagaaa aaatcgaaaa attagctaag aaatattctg
    65401 ataacttaaa catcaaagtt caagagagag ttcgtgaaat ggcaaatgat aataagagcc
    65461 attatttgat atacagagtt ttaggtattt catttgaaga aggagaaaat atcgatttgt
    65521 atcaaaataa aggtcgtttt ttatacaaat atgctggttc atttttagaa gaagctgcag
    65581 tactatcctt taacgaaaaa tttggtacag aaaatactta aaaagttaac attcctaatt
    65641 ctgaaagtac aaaacctaag acttttgaaa ttgattgttt agtcggagaa aaacacgcat
    65701 acgaaataaa atggtgggat gcaactacag atggagacca tataactaaa gaacacacta
    65761 gaataaaagt tattcataac aaaggatata taccaattcg gttaatgttc tactatccaa
    65821 atagaactca agctataaaa attcagcaaa ctttagaaac attgtataac ggtattggag
    65881 ggaaatatta tggagattct gcctgggaag atttaagagc agtgaccggt attgatttac
    65941 ttagtattct aacagatatt gcaaataaaa aacaggggta aaatcaaaat gacagtatta
    66001 aaaggagata acttagaaat attaaaaact attgaatcct caagtattga tttaatctat
    66061 atggaccctc ctttctttac acagaaaacc caaaaattat ctaataacaa aaatattatg
    66121 tattcattcg aagatacgtg gacttcgatt gaggattaca aagaattttt gtctgtaaga
    66181 ttagaagaat gcaaaagagt gctaaaaaat agtggcagta ttttcgttca ttgtgataaa
    66241 attgcaaatc atcatattag attaatttta gataatatct ttggagcaga tatgtttcaa
    66301 agcgaaatta tatggaacta taaacggtgg tctaattcaa aaaagggatt attgaacaat
    66361 catcaaaaca tttactttta ttcaaagtca aaagatttta aatttaatac aatttttaca
    66421 gagtattctt ctactacaaa tatcgaccaa atactagtgg aacgaaaacg agatggaaac
    66481 tctaaaacta tatataaagt tgataataat ggtaactata ttctagcaaa agagaaaaat
    66541 ggagttcccc tttcagatgt ttggaatata ccatttctta atccaaaagc taaagaaaga
    66601 gtaggttatc ctacacaaaa acctattctg ttattagaac aaattataaa gattgctact
    66661 gataaaaatg atatagtttt agacccgttc tgtggaagtg gaactacttt agtagcctcc
    66721 aagattttga atagaaatta tatggggatt gatttatctg aggaagctat caatataact
    66781 cagcaacgtc tggaaaatgt tataaaaaca agttcagatt tattgaataa aggaatcgaa
    66841 gcatatagaa ccaaaactga ggaagaggaa aacattctta aattattaca ggcaaaaatt
    66901 gttcaaagaa ataaaggaat tgatggtttt ttacctaaac attttcaaaa aaaaccgata
    66961 cctataaaaa ttcaaaaaaa taatgaatgt ctgaatgaga gtatctcttt attacagaat
    67021 gctataaact ccaaaaaact tgattttgga gtagttataa aaactcattc agataattta
    67081 ttatttgatt ttgatacgat tcctgaaaat ataatagtag ttgaccattt tgaacttaca
    67141 atcgaaaaat ggttaagtaa aagtcaacag ttactatagt ttgcaaatta tttacagaaa
    67201 gaacaaaaaa tgctctgaaa cactgatttc aaggcatttt ttgttagttt aaaattactc
    67261 ccattcttct tttccaaaca tacaatatat ccaaaaccat tcaaaatact agattctatt
    67321 ttttataata tcactaaatc cacctaatta taggacgttt tcagattttt agtcccgtcc
    67381 cagtcccagt accggagaaa tattgtttta atataatatc tctttttgtc ttctaagctc
    67441 ttaaaagcaa aagaacaagt aaagagtcaa gacaaggata aaaagtccat attagggcaa
    67501 ataaaaagct ttaagacaga tgacaaatct aagtcaaata agaaagacca tagcaaaggt
    67561 gcagagagat aaatattggc ggtcttcgga ctgcctttat ttttttatcc atttttcaaa
    67621 tcaaatttat tcagactata tatgcacata tacacttaaa ttcatataaa aacatggctt
    67681 gtaaaaaatt actttaatca caataatcgc atttaaaatt gtgatgtttg caagctaaat
    67741 tacggacttc acttggaagt tttcccttgt atcttttata atagatagaa aatttgctgg
    67801 cagatgaata tccaacagat tctgctatct cttttatagg tagttcagtg tttaaaagaa
    67861 gagtttcagc tacattcatt ctttttcttt gagtgtactc tgtaatgctt tgacaatatt
    67921 tttccttaaa taaatttttt aatttagtac cactcatttt agatattttt tcaagcgtgc
    67981 cttgatttac attcgttgca aaatgatcat ctaagaatct tgctacatct tcaagtgctt
    68041 tatcatcatc aatttcaatt ttatattttt ttctatttaa gtatgtgtca attactatac
    68101 ttatccattc atttgccttt gctttaaaga aaaaatcagc ggcaggagcg tccatcttac
    68161 aatttaatat ttccattgcc actctttcta aggcctttgt aagtattatt tgattcgatt
    68221 gaagcaaggt tgaataaaaa gattctggat taatgttaat agatgctaaa tgtttttcta
    68281 ttagctcttt tttaaaacca atggaaacag caagataaca acaattctcg tgtaataaaa
    68341 aaacaaaatc atcttttata ttatcaaaat caaaagtaca taaagagttt gcggtaatag
    68401 tttgatacgg attaaacttt tctccgtttg cactgacaat gtaacttgaa taaattgaaa
    68461 catagtctga catactataa gtgctatttt gaactacttc ctctttgata taaaaatcat
    68521 gtatatcgat aatgaagctg cctccttcat aaaaccaata taggccttct gcataagttg
    68581 aattctcttt tttccaacaa aatgtatgac ctgcacttga atacttctca ttgtttttac
    68641 attcatctac tttcatataa tcttttacaa aatcataata tgacataaca cactatccct
    68701 tttagacaat attccaatta gccttattaa ttcaaaacta ttgtattagt aattataaca
    68761 gatgtataat agaaaagcaa tgatagatat tatcaattaa gcgaatttat atctaaaagg
    68821 gatattaaag aaaggagata tgcttatgaa gatttacaaa aaactatttg cttatgtcca
    68881 agataagaaa tatcttgggg ttttggccat aattttttct gctatatctg ctgcacttac
    68941 agtatatgga tattatttaa tctacaaatt tctagataag ttaataatta attcaaactt
    69001 atccggtgca gagagtatag cattaaaatc tgttattaca ctaacaagtg gagcgatatt
    69061 ttattttgtc tcaggaatgt tttcacatat cttgggattt aggcttgaaa caaatttaag
    69121 aaaaagggga atcgatggtc tggaaaaagc aagttttagg ttctttgact taaatccatc
    69181 tggtcaaata agaaagatca tagatgataa tgcagcacaa actcatcagg tggtagcaca
    69241 catgattccc gatagttctc aggcaataat cacacccgta cttgtacttg cacttggctt
    69301 tatagtaagt ataagggttg gcataatttt gcttgctctt actataattg gtggcttaat
    69361 tttaggggca atgatgggcg agcaagaatt tatgaagata taccaagaat ccctatctaa
    69421 actaagtgct gaaactgttg agtacgtgag aggaatgcaa gttgtaaaaa tatttaaagc
    69481 aaatgtagag tcttttaaaa gcttttataa ggcgataaaa gattactcaa agtatgctta
    69541 tgattattcc ctatcttgta aaaggcctta tgttttgtat caatggttat tttttggact
    69601 gattgcaatt ttaattattc ctatagttta ttttatgact agcttagcta gcgcaaaggt
    69661 gattttactt gagcttatca tgattttatt tttatcagga gttctctttg tttcattcat
    69721 gagaatgatg tggtactcca tgtatatttc tcaaggaaat tatgcagtag atactttaga
    69781 ggcgctttac gaagatatgc aaaaagacaa attagtgcat ggtaatgtca ataattttaa
    69841 aaactataat atagaatttg agaatgttag ctttgcttat aatgataaag ctgtcattga
    69901 aaatttatcc tttaatttag aagaaggaaa gtcctacgca cttgtcggtt catctggatc
    69961 aggcaaatca acagtagcaa aacttatatc aggtttttac aatgttaata aaggaagcat
    70021 aaagataggc gggatagcaa taagtgaata ttctgacgaa gccttaatta aagccatttc
    70081 ctttgttttt caagattcaa aattattcaa gaagagcatt tatgataatg tagctttagc
    70141 taataaagat gcgacgaaag atgacgttat gagagcctta aaattagcag gatgcgattt
    70201 aatattagac aaattcccag aaagagaaaa tacaatcata ggctcaaaag gtgtttattt
    70261 atccggtgga gaaaaacaaa gaattgcaat tgctagagca attttaaagg attccaaaat
    70321 tattattatg gatgaagcat cagcatctat tgacccagat aacgagtttg aattgcaaaa
    70381 agcttttaaa aatcttatga aggataaaac agttatcatg attgcacaca ggctatctac
    70441 aattaaagac cttgatgaaa ttattgtcat ggatagtgga aaaattatag aaagagggtc
    70501 tgacaaagaa ttaatgtcaa aagatacaag gtataagagc ctgcaagaga tgtttaacag
    70561 tgcgaatgaa tggagggttt caaatgaaag agttttataa aaaaagattt gctcttacag
    70621 atggaggagc aagaaattta agtaaagcaa cactggcttc atttttcgtt tattgtataa
    70681 acatgcttcc tgccatatta cttatgattt ttgctcagga agttttggaa aatatgggca
    70741 aaagcaatgg cttttatata gtattctcag ttttgacttt gatagcaatg tatattttgc
    70801 tttctatcga atacgataaa ttatataaca caacctatca agaaagtgca gatttaagaa
    70861 taaggacagc ggagaattta tcaaaattac ctctatctta cttttctaaa catgacattt
    70921 ccgacatttc acaaacaatc atggctgata ttgaaggcat agagcatgca atgagccact
    70981 caataccaaa ggtgggcggc atggtactgt ttttcccatt aatatctgta atgatgctag
    71041 cgggcaatgt caagatgggt ttagctgtaa ttattccatc tattttaagc tttatattta
    71101 tacctttatc taaaaaatat caggttaatg gacagaatag atattatgat gtcttaagaa
    71161 aaaactcaga aagctttcaa gaaaatatcg aaatgcaaat ggagattaaa gcatataatt
    71221 tatcgaagga tattaaagat gacttatata aaaaaatgga agatagtgag agagtacact
    71281 taaaggcgga agtaactaca attttaactt tgtctatatc ttcaatattt agctttatat
    71341 ctcttgctgt tgtgatattt gtcggcgtaa atctaattat taataaagag ataaattctc
    71401 tctaccttat aggatattta ctagctgcta tgaagataaa agactcttta gatgcatcta
    71461 aagagggctt gatggaaata ttttatttat cgcccaaaat agaaagatta aaagaaattc
    71521 aaaatcaaga tctacaagaa ggcgatgact atagcttaaa aaaatttgat attgatctaa
    71581 aagatgttga gtttgcctac aataaagacg caaaagtttt aaatggtgta agttttaaag
    71641 ctaagcaggg agaggtcact gctttggtag gtgcaagtgg ctgcggtaaa acaactatct
    71701 tgaaacttat atcaagactt tatgattatg acaagggaca aatcttaatc aatggcaaag
    71761 atataaaaga aatatcaaca gaatctcttt ttgataaggt ctctatagtt ttccaagatg
    71821 tggttctctt taatcaaagc gttatggaaa atattagaat cggaaagcaa gatgcaagtg
    71881 acgaagaggt taaaagagca gcaaaacttg caaattgcac agattttata gaaaaaatgg
    71941 ataaaggttt cgatacagtt attggtgaga acggagctga gctatcagga ggagaaagac
    72001 aaagattatc aatagccaga gccttcttaa aagatgcgcc gatattgatc ttagatgaga
    72061 taacagcaag ccttgatgtt aacaacgaga aaaagattca agagtcttta aataatttag
    72121 ttaaagataa aactgttgta atcatttcac atagaatgaa atccatagaa aatgcagaca
    72181 agatagtagt tcttcaaaac ggaagagtag aaagcgaagg taagcatgaa gagcttttac
    72241 aaaaatcaaa aatttacaaa aatttaatag aaaagacaaa aatggcagaa gaatttattt
    72301 attaggagga ctacaatgga taataaaaaa ttaaaagtaa aagatttagt aagcatcggt
    72361 gtttttggcg taatttattt tgccttcatg tttggagttg gtatgatggg cttgattcca
    72421 atattgttct taatataccc gacagtatta gccatagttg caggaactgt tgttatgtta
    72481 tttatggcta aggttcaaaa gccatgggca ctatttatat ttggtatgat atcaccactt
    72541 gtgatgtttg cagctggtca tacctacgta gttgtggttt tatcacttat agtaatgata
    72601 atagcagaat taattagaaa gattggtaat tataattcat ttaaatacaa tatgctttct
    72661 tatgcaatct tcagcacatg gatatgtagc tctttaatgc aaatgctttt agcaaaagaa
    72721 aaatatatgg agtggtcttt gatgacgatg ggaaaagatt atgttgatgt attagaaaag
    72781 ttaataactt atcctcacat ggctttagta gccttaggtg ctttcttagg aggaattctt
    72841 ggagcatata taggcaaggc tctattgaaa aaacactttg aaaaagcagg cattgtataa
    72901 tgcctacttt ttcttcaaat gctcccttta atcccaatcc gatctctaag atattagtcg
    72961 tatttatcac aggcttaact gttatgcata gcataaacat ccgttttgag ctggcaattg
    73021 tttgtcttat tggtattttg ctttatttga atggatacaa aaaaacactt ttcaaatgga
    73081 ttatattgtg tgggatactt tactccttgc ctaattttat ggtgttatct gaattaaacc
    73141 ctatagttaa gatgtttttg agtataccta ttgttattat aatgtttatt ttaccattta
    73201 tggcagcaag ctttatgata aagacctcgg atgtaggcgc aataatttca tcgatggata
    73261 agcttaagat ttcaaagaat gtatccatac ctattgcggt tatgtttaga ttcttcccat
    73321 cttttaagga ggagaagaaa aacatcaaaa tggctatgag agtaagaggg ataaatttta
    73381 aaaacccagt caaatatctt gaatatgttt ctgtgccact actcattata tcatctaata
    73441 tatcagatga cattgcaaaa gcggcagaaa caaaggcaat agaaaatcca attgccaaga
    73501 ccagatacat tcgcgtaaag atacagctaa ttgattttgt ttatgtttta gcggttgttg
    73561 gacttattgt gggaggctta atatggttga aataaaaaat ttaagtcttg attatggtga
    73621 agagcatata ttagatgata tatcactatc catagccgag ggagagtgcg tgctatttac
    73681 aggaaaaagt ggaaatggta agtcatcttt aataaattca atcaatggac tagctgtaag
    73741 gtatgacaac gcaaagacaa agggcgaaat cattattgat ggtaagaata taaaaaattt
    73801 ggaactttat caaatctcaa tgcttgtttc aactgttttt caaaatccta agacatattt
    73861 ttttaatgtc aatacgacat tagaattatt attttatttg gaaaatatcg gtcttgcaag
    73921 agaagagatg gacaggcgtt tgaaggatat gcttaagata ttcccgataa aaaatctttt
    73981 gaacagaaat atatttaatc tatccggcgg tgaaaaacaa attctttgca ttgcagcttc
    74041 ttatatagca ggtacaaaga ttatagttat ggatgagcct tcatcgaatt tagatattaa
    74101 aagcataagt gttttggcaa agatgctaaa gatattaaaa gagaaaggta taagcataat
    74161 tgttgcagag catagaattt attatttgat ggacatagtt gaccgtgtat ttttaataga
    74221 taaaggaaag cttaaaaaaa cttatactag aagtgaattt ttaaagctag ataaaaatga
    74281 attaaatgct ttaagtttaa gagataaaga attaagtaaa ttaaaagttc cttatttaaa
    74341 agaaggtgga gagtatcaga taaaaaatct tagctacaaa tttactgatg atgagtgttt
    74401 aagcttaaaa gatatttcat tcaagcttgg gaaaatttat ggcataatag gatccaacgg
    74461 acgaggaaaa tcaacgcttt taagatgttt aataggtctt gagaaaaaat caaaagaaga
    74521 aatttatttt aagggagaga agctatctaa aaaagaaaga ctcaaaaact cttcacttgt
    74581 tatgcaagat gtaaatcatc aattattcac agatgaagta ttcaacgagc ttagattagg
    74641 agtaaagaat tttgatgaag aaaaggcgaa aatcatttta aaagatttag gcctggacga
    74701 atttattgaa aggcatccga tgagtttatc aggagggcaa aagcaaaggc ttgcaatagc
    74761 atctgttatg tgcaagactt ctccatttgt cttttttgac gaaccttcaa gtggtatgga
    74821 ttattccaat atgataaaaa tatctgaact gattaataag tataaaacca tggataaaat
    74881 aatttttatt gtttcccatg atatagaatt tttaaatgaa gtggcagatg aaatttttga
    74941 attgtaaaat agagtctgtt aaacatgtct atagaactag taaattgtct aaaaatttaa
    75001 aagatactaa cacatattga tatttattag aaaattaact tcaggatttt tacagtattt
    75061 ataaacttta taatatgtat ttatagtatt aataatttcc atatctttag ggaaattctt
    75121 tatttactta ccataattaa agagatgaga gataaatatc ggcagtcttc ggactgcctt
    75181 tattttttta cttaatttaa tgcagtaaat catacgattg aaaggaatct gcgttatatg
    75241 ctataattag gtggttaatc tatacattta gaaaggtaaa atatagaatt ggagaatgat
    75301 atgggatttt catataataa attgtaaccg tccaataacg aagtatattg aaaaatctcc
    75361 agactagaga actca
//
LOCUS       DAVBNZ010000002        69961 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000002 DAVBNZ010000000
VERSION     DAVBNZ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.002"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            624..1265
                     /locus_tag="VQ860_000078"
     CDS             624..1265
                     /locus_tag="VQ860_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3118586.1"
                     /translation="MTIESGQRIALVGQPGSGKSTLSKIPSGLYKIDTGKVLFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            1278..1448
                     /locus_tag="VQ860_000079"
     CDS             1278..1448
                     /locus_tag="VQ860_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118587.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(1944..3290)
                     /gene="gdhA"
                     /locus_tag="VQ860_000080"
     CDS             complement(1944..3290)
                     /gene="gdhA"
                     /locus_tag="VQ860_000080"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET3118588.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGIICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            3822..4278
                     /locus_tag="VQ860_000081"
                     /pseudo
     CDS             3822..4278
                     /locus_tag="VQ860_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            4281..5293
                     /locus_tag="VQ860_000082"
                     /pseudo
     CDS             4281..5293
                     /locus_tag="VQ860_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            5268..5846
                     /locus_tag="VQ860_000083"
     CDS             5268..5846
                     /locus_tag="VQ860_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HET3118589.1"
                     /translation="MVRNYWKARSWLLVLALSFLILSPVGAQESLSSYFVKITDTSKA
                     VKNGNQSEAQKLVQEMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSIAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(5903..6187)
                     /locus_tag="VQ860_000084"
     CDS             complement(5903..6187)
                     /locus_tag="VQ860_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET3118590.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(6241..7176)
                     /locus_tag="VQ860_000085"
     CDS             complement(6241..7176)
                     /locus_tag="VQ860_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET3118591.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVSAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            7280..7723
                     /locus_tag="VQ860_000086"
     CDS             7280..7723
                     /locus_tag="VQ860_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET3118592.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            7839..8105
                     /locus_tag="VQ860_000087"
     CDS             7839..8105
                     /locus_tag="VQ860_000087"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET3118593.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            8102..8476
                     /gene="crcB"
                     /locus_tag="VQ860_000088"
     CDS             8102..8476
                     /gene="crcB"
                     /locus_tag="VQ860_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3118594.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            8470..8799
                     /gene="crcB"
                     /locus_tag="VQ860_000089"
     CDS             8470..8799
                     /gene="crcB"
                     /locus_tag="VQ860_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3118595.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQVSKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            8918..9265
                     /gene="rplS"
                     /locus_tag="VQ860_000090"
     CDS             8918..9265
                     /gene="rplS"
                     /locus_tag="VQ860_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET3118596.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            9307..9378
                     /locus_tag="VQ860_000091"
     tRNA            9307..9378
                     /locus_tag="VQ860_000091"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9340..9342,aa:Arg,seq:cct)
     gene            complement(9544..10542)
                     /locus_tag="VQ860_000092"
     CDS             complement(9544..10542)
                     /locus_tag="VQ860_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET3118597.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNKLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLKVVELKTILSKHN
                     LATSGKKAELITRIINNINVDKLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(10585..11391)
                     /gene="yidA"
                     /locus_tag="VQ860_000093"
     CDS             complement(10585..11391)
                     /gene="yidA"
                     /locus_tag="VQ860_000093"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET3118598.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKSNDESGVAHAIRTWVL"
     gene            complement(11404..12708)
                     /locus_tag="VQ860_000094"
     CDS             complement(11404..12708)
                     /locus_tag="VQ860_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET3118599.1"
                     /translation="MNEKVFRDPVHNYIHVINQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            12780..13157
                     /locus_tag="VQ860_000095"
     CDS             12780..13157
                     /locus_tag="VQ860_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET3118600.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKNSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            13248..13580
                     /locus_tag="VQ860_000096"
     CDS             13248..13580
                     /locus_tag="VQ860_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET3118601.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            13592..15163
                     /gene="ffh"
                     /locus_tag="VQ860_000097"
     CDS             13592..15163
                     /gene="ffh"
                     /locus_tag="VQ860_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET3118602.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPN
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15358..16641)
                     /locus_tag="VQ860_000098"
     CDS             complement(15358..16641)
                     /locus_tag="VQ860_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET3118603.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(16895..17608)
                     /gene="rsmG"
                     /locus_tag="VQ860_000099"
     CDS             complement(16895..17608)
                     /gene="rsmG"
                     /locus_tag="VQ860_000099"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET3118604.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            17702..18262
                     /locus_tag="VQ860_000100"
     CDS             17702..18262
                     /locus_tag="VQ860_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET3118605.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            18264..19163
                     /gene="htpX"
                     /locus_tag="VQ860_000101"
     CDS             18264..19163
                     /gene="htpX"
                     /locus_tag="VQ860_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET3118606.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(19207..20766)
                     /locus_tag="VQ860_000102"
     CDS             complement(19207..20766)
                     /locus_tag="VQ860_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3118607.1"
                     /translation="MHYEHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLELVNLEDL"
     gene            21491..22033
                     /locus_tag="VQ860_000103"
     CDS             21491..22033
                     /locus_tag="VQ860_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET3118608.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            22033..22662
                     /gene="nth"
                     /locus_tag="VQ860_000104"
     CDS             22033..22662
                     /gene="nth"
                     /locus_tag="VQ860_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET3118609.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            22873..23394
                     /gene="pyrR"
                     /locus_tag="VQ860_000105"
     CDS             22873..23394
                     /gene="pyrR"
                     /locus_tag="VQ860_000105"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET3118610.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            23413..24336
                     /locus_tag="VQ860_000106"
     CDS             23413..24336
                     /locus_tag="VQ860_000106"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET3118611.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            24386..25465
                     /gene="carA"
                     /locus_tag="VQ860_000107"
     CDS             24386..25465
                     /gene="carA"
                     /locus_tag="VQ860_000107"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET3118612.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEKARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            25778..28954
                     /gene="carB"
                     /locus_tag="VQ860_000108"
     CDS             25778..28954
                     /gene="carB"
                     /locus_tag="VQ860_000108"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET3118613.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELSVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(29229..30038)
                     /locus_tag="VQ860_000109"
     CDS             complement(29229..30038)
                     /locus_tag="VQ860_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3118614.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(30040..30843)
                     /locus_tag="VQ860_000110"
     CDS             complement(30040..30843)
                     /locus_tag="VQ860_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3118615.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(30853..32340)
                     /gene="tacF"
                     /locus_tag="VQ860_000111"
     CDS             complement(30853..32340)
                     /gene="tacF"
                     /locus_tag="VQ860_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET3118616.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            32676..33383
                     /locus_tag="VQ860_000112"
     CDS             32676..33383
                     /locus_tag="VQ860_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET3118617.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            33388..34410
                     /locus_tag="VQ860_000113"
     CDS             33388..34410
                     /locus_tag="VQ860_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3118618.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            34427..35296
                     /gene="licA"
                     /locus_tag="VQ860_000114"
     CDS             34427..35296
                     /gene="licA"
                     /locus_tag="VQ860_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET3118619.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLVKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLVEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            35286..36164
                     /locus_tag="VQ860_000115"
     CDS             35286..36164
                     /locus_tag="VQ860_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET3118620.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            36176..36865
                     /locus_tag="VQ860_000116"
     CDS             36176..36865
                     /locus_tag="VQ860_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET3118621.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            36963..37811
                     /gene="dprA"
                     /locus_tag="VQ860_000117"
     CDS             36963..37811
                     /gene="dprA"
                     /locus_tag="VQ860_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET3118622.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            38695..39738
                     /locus_tag="VQ860_000118"
     CDS             38695..39738
                     /locus_tag="VQ860_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET3118623.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            39905..41992
                     /gene="topA"
                     /locus_tag="VQ860_000119"
     CDS             39905..41992
                     /gene="topA"
                     /locus_tag="VQ860_000119"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET3118624.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            42098..42457
                     /locus_tag="VQ860_000120"
     CDS             42098..42457
                     /locus_tag="VQ860_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET3118625.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            42550..43182
                     /locus_tag="VQ860_000121"
     CDS             42550..43182
                     /locus_tag="VQ860_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET3118626.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            43226..43882
                     /locus_tag="VQ860_000122"
     CDS             43226..43882
                     /locus_tag="VQ860_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET3118627.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            43901..44533
                     /locus_tag="VQ860_000123"
     CDS             43901..44533
                     /locus_tag="VQ860_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET3118628.1"
                     /translation="MNFQLAEYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            44561..44995
                     /locus_tag="VQ860_000124"
     CDS             44561..44995
                     /locus_tag="VQ860_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HET3118629.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            45007..46044
                     /gene="leuB"
                     /locus_tag="VQ860_000125"
     CDS             45007..46044
                     /gene="leuB"
                     /locus_tag="VQ860_000125"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET3118630.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            46041..46310
                     /locus_tag="VQ860_000126"
     CDS             46041..46310
                     /locus_tag="VQ860_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET3118631.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            46314..46673
                     /gene="leuD"
                     /locus_tag="VQ860_000127"
     CDS             46314..46673
                     /gene="leuD"
                     /locus_tag="VQ860_000127"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET3118632.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIVAYEKQRPAYWQD"
     gene            46835..47459
                     /locus_tag="VQ860_000128"
                     /pseudo
     CDS             46835..47459
                     /locus_tag="VQ860_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            47622..49535
                     /locus_tag="VQ860_000129"
     CDS             47622..49535
                     /locus_tag="VQ860_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET3118633.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSGGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNDQ
                     TGQQDTGDNDADY"
     gene            49522..50838
                     /locus_tag="VQ860_000130"
     CDS             49522..50838
                     /locus_tag="VQ860_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET3118634.1"
                     /translation="MRITDNQYKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            51013..51999
                     /locus_tag="VQ860_000131"
     CDS             51013..51999
                     /locus_tag="VQ860_000131"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET3118635.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            52063..52134
                     /locus_tag="VQ860_000132"
     tRNA            52063..52134
                     /locus_tag="VQ860_000132"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52096..52098,aa:Arg,seq:ccg)
     gene            52317..53015
                     /locus_tag="VQ860_000133"
     CDS             52317..53015
                     /locus_tag="VQ860_000133"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET3118636.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            53006..56545
                     /gene="smc"
                     /locus_tag="VQ860_000134"
     CDS             53006..56545
                     /gene="smc"
                     /locus_tag="VQ860_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET3118637.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAVSPGFLGMADELVTFDTRLEAIFKNLLDTT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMATLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEKDRLSDGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNFQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHSRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPQGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            56542..57336
                     /locus_tag="VQ860_000135"
     CDS             56542..57336
                     /locus_tag="VQ860_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3118638.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            57336..58154
                     /locus_tag="VQ860_000136"
     CDS             57336..58154
                     /locus_tag="VQ860_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3118639.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKSTLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISLELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKVAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            58158..59447
                     /gene="ftsY"
                     /locus_tag="VQ860_000137"
     CDS             58158..59447
                     /gene="ftsY"
                     /locus_tag="VQ860_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET3118640.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDLTFTEADEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(59491..60978)
                     /locus_tag="VQ860_000138"
     CDS             complement(59491..60978)
                     /locus_tag="VQ860_000138"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET3118641.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     VELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(61127..61867)
                     /locus_tag="VQ860_000139"
     CDS             complement(61127..61867)
                     /locus_tag="VQ860_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3118642.1"
                     /translation="MAKLKIDVNDLHKYYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(61867..64032)
                     /locus_tag="VQ860_000140"
     CDS             complement(61867..64032)
                     /locus_tag="VQ860_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3118643.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            64205..65158
                     /locus_tag="VQ860_000141"
     CDS             64205..65158
                     /locus_tag="VQ860_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3118644.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            65235..67223
                     /gene="uvrB"
                     /locus_tag="VQ860_000142"
     CDS             65235..67223
                     /gene="uvrB"
                     /locus_tag="VQ860_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET3118645.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            67233..67796
                     /locus_tag="VQ860_000143"
     CDS             67233..67796
                     /locus_tag="VQ860_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3118646.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            67762..68250
                     /locus_tag="VQ860_000144"
     CDS             67762..68250
                     /locus_tag="VQ860_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3118647.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDDTIQAGGIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            68324..68791
                     /locus_tag="VQ860_000145"
     CDS             68324..68791
                     /locus_tag="VQ860_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3118648.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(68788..69303)
                     /locus_tag="VQ860_000146"
     CDS             complement(68788..69303)
                     /locus_tag="VQ860_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET3118649.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(69315..69842)
                     /locus_tag="VQ860_000147"
     CDS             complement(69315..69842)
                     /locus_tag="VQ860_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3118650.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT        21394 a        12500 c        15212 g        20855 t
ORIGIN      
        1 aaaagcgtcg ttaatgatgc attaaagaac agtcgagatg aaaaaatcat gtgacgcacc
       61 aagggaggag tctgcccttt tgaggaaatc tagcgaggaa aaacgatact ggaacagcag
      121 aaagtaaaac tgacctcatg aggaggaaga aagtggctca tgaggtcagg ggttttgtaa
      181 gttacatcta gttgagagag gtatgaatga tttgggttta atcagatggt ttacctcctt
      241 ttcatcggta ttcaccactt tttcaatagt aaagacgaga tggtcttgcg gcaagaaaga
      301 actgatttct agtggtaaag ttgtttgatt tgtgttatag tgaatatgca tgggatagcc
      361 cttctaaatg gtttattggg caattctatt ttaccaagac tatcgcaacc atgcaaaaaa
      421 gcaacggcaa atccgcttct tttttggaga taagagacta ttgtcccaga ctcttagtac
      481 tggttggagg atacgatgaa agatagttat tggttaaatt attttccgga gtatagttta
      541 gaaacgtttg aagtagaata gatattaagg acctatcttt ctcttattcc aaagactcag
      601 ctcttgtaat agaaaattta aatttgacta ttgagtcagg acagagaatt gcactagtcg
      661 gtcaaccggg gtcaggaaaa agtacattat caaaaatacc atcaggatta tataagattg
      721 atacaggaaa agttttattt gatggtgtaa atattaatca aatagataaa aaaatattaa
      781 gtcaaaattt aggagtagtt ccacaggatt cgtttttatt gaacagaagt attcttgata
      841 acataacttt aaagcacgaa gttacttcac aaaagataga ggaagtttgt aaagcagttc
      901 aaatctatga tgaaatcatg gctatgccga tgaaatttaa tactatcatc tcagagatgg
      961 gttcaaatat ttcaggtggt caaagacaac ggatagcact ggcacgtgca ttaataaata
     1021 atcctagtat tgtaatttta gatgaagcaa ctagtgcttt agacactatt aatgaggaaa
     1081 gaataacaaa gtatataaaa agtcagggct gtactcaaat aattgtagct catagattgt
     1141 caacgattaa ggatgcggat attattgttg taatgaaagg tggtaagatt gttgagtcag
     1201 gaaatcataa gtacttaatg gatcttggtg gagagtacta cagcttatat acaaaaagga
     1261 aatgaggtgt aaagaaaatg aagaaagaaa atgaatatgt aattttaaca acagcctcac
     1321 taggggtgat gattggaata gtgtttgcaa tttttttaga ttttccagtt gaatatggta
     1381 tttctttagg attgttgaat ggaatagtat tgggttcgct gattgtttac aaaaacaata
     1441 agaattaagc ataatttttt gctgtaaact aaggagtaga gatggctata gttgaaatta
     1501 taaatctaac aaaaagcttt aaagatattg aagttattca taacacttaa ataatagagc
     1561 aactacagta gtagcttaaa aacatgatta aatcgctatt cttaggagta gcgttttttc
     1621 tttttgttta atactctttg aaaatctctt caaaccacgt cagctttgcc ttgccgtact
     1681 caagtacagc ctgcgactcg cttcctagtt tgctctttga ttttcattga gtataaaaag
     1741 ggttaagtaa gtatagtaaa ttgaaataag atatgaacaa atcgattaga aaagtcaaat
     1801 taatttctag aaatatgtta gaaattggtt tgaattccgc aatcaatttg ttcagttttt
     1861 atttcattta attagaattt cccaactgtc taactcaact aaaaatcccc aatcgtagtg
     1921 attgaggatt aagcaaataa atcttaaaca ataccttggg caatcatagc gtttgctaca
     1981 ttttcaaagg cagcaatgtt agctcctgca aggtagtctt tatcaagacc gtatgtttct
     2041 gaagtcgttt tagctgtgtt gaagatgttt gtcatgatgt ctttgagacg gtcatcaact
     2101 tcttcacgag tccatgagag gcgaagactg ttttggctca tttcaagagc tgaaacggct
     2161 acaccaccag cgttggcagc ttttgcaggt ccgtataaga taccattttc tttgtaaact
     2221 ttgatggcat caaggtcgct cggcatgttg gcaccttcag atacacagat aatgccttga
     2281 gcaaccaaac gtttagctgc ttcaccgttg atttcgtttt gagtggcaca tggaagagca
     2341 atgtcatagt ttccagcgta agtccataca gtaccttcgt ggtaggttgc agttgctttt
     2401 tcagctgcat actcagtcaa acgagcacga cgtttttctt taacatcaac caaaagatcg
     2461 aagtcgatac cattttcatc gatgacataa ccatttgagt cagaaacaga aataacagtt
     2521 gcaccgagtt cagttgcttt ttgaagagca tattgagcaa cgttaccaga acctgaaata
     2581 acgactttct taccagcaaa gctgttaccg ttagctttga gcatttcttc agtatagtaa
     2641 accaaaccgt aaccagttgc ttctggacga atcaagctac caccaaatcc aagaggttta
     2701 ccagtcaaga caccagcatc aaattggtta agacgtttgt attgaccgta aaggtaacca
     2761 atttcacgtc caccaacacc gatatcacca gcaggtacgt caagtgatgg tccgatgtgt
     2821 ttttgcaatt cagtcatgaa gctttggcag aagcgcatca cttcagcatc tgttttacct
     2881 ttaggatcga agtctgatcc acctttacct ccaccgatag gaagtccagt caagacattt
     2941 ttaaagattt gttcaaatcc gaggaatttc aagatccctt ggtttacagt tgggtggaaa
     3001 cgaagtccac ctttgtatgg tccaacagct gagttgaatt gaacacggta accacggttt
     3061 acttgaattt ttccatcacg gtcaacccaa ggaacacgga aagaaaccac gcgctcaggc
     3121 tcagtaatac gtgccaagat attttcttcg atatactcag ggtgtttttc aaatacaggt
     3181 tctaaagtgt tgaaaaattc ttcaacagct tggaggaatt cagcctcgtg cccgttacga
     3241 gctttcacag tttcaaacac gctttggata tattctttag cagatgtcat atcgttctcc
     3301 ttttattgtc atattttatt acataagaca ttatagcaga attttttttc actgtaaaga
     3361 aaaaacagaa attttctaaa aattctttca attcagtttt ttggtttttt tgaaaataga
     3421 taaaaaaacg aacgtttttc ttggaaatat ctttctcaaa gacaaaatct taaagtatgc
     3481 tataagaaaa gaaaatgttt agcaattcag aaatcacttg ttaatttatc cgtgatatgt
     3541 tagatttgcc agtaaaacta tgaccatttt ggagaaaagc aatatttaga ctagactaaa
     3601 ataaaaaagt attatataat agtgatatga aatcaactaa agaagaaatc caaaccatca
     3661 aaacactttt aaaagactct cgtacagcta aatatcataa acgccttcaa atcgttctat
     3721 agtaaaacga aacaagaaca gggcaaatcg atcaggacag tcaaatcgat ttctaacaat
     3781 gttttagaag tagaggtgta ctattctagt ttcaatctac tatatttcgt ctgatgggca
     3841 aatcttataa agagattata gagcttttag actgtaatca aacaacgatt tggcgaaatg
     3901 taaaaaaata tgaggagttc ggactcgact ctctctttca agaaacacgt ggtggtcgta
     3961 accatgcata tatgacggtt gagcaagaga aagcctttct tgctcgccat ttgaaggctg
     4021 cagaggcagg agaatttgtt acaattgatg ccttatatca ggcttataaa aaggagttag
     4081 gtcgttccta cacacgtgat gccttctatc aactgttgaa gcaccatggt tggcgaaata
     4141 ttatgccacg tccagaacat cctaggaaag cagacgctca aaccattgtc gcgtctaaaa
     4201 ataaaatctt aattcaagaa gacaagaaag cgctttaaat atagtagacg ttttcgtaag
     4261 gttcgcttga tgtaccaaat agtacgccca tgcaaaagaa tatctatttt gttgtcttgg
     4321 acctgcatac gacggataga gataaaatta tccagctatt caaggattgg acggattata
     4381 gtgccaagtt ggtcgagggg gaattggtta aaaaagatgg acagaatgct ctctttcctc
     4441 cgagcgatac tggtgagaca gttgggctca atcctcatcg tttgacgctg acttttggtg
     4501 tatctgcaag tttcttgaaa aagatgaact tggaaaacaa gcgccctcga ctgttcaggg
     4561 atttacctct atttcctaag gagcaattac gtgaaaaata tactggtgga gatattgtga
     4621 ttcatgcttg tgcagatgat gagcaaattg cctttcacgc tattcgcaat ctcatacgta
     4681 aggggagaaa tgcggtgccc cttcgttgga gtcagtctgg atttgcagct atcggggacc
     4741 gaatggagac tccgcggaac ctctttggtt ttaaggatgg aacagcaaat ccaaccaagg
     4801 agcaagactt tgaccgcgtt atctgggctg atagtaagga ctggatggaa aatggttctt
     4861 atatggcagt tcgtcggatt cagatgtttt tagagacctg ggaccgcact ggtctctaag
     4921 aacaagaaaa tacctttggt cgttacaagg aaagtagtgc ccctttcggt aaaaaaatga
     4981 gtttgatgaa gtgaatttga gttttttgct agatgattcg catgttcgtt tggctaagta
     5041 agtggacaag ccacttttgc gttgttctta ctcttactca gatggcattg atgaaaagac
     5101 tggtcagttt gatacgggtt tgctcttcat ttctttccag aaggatcctg ataactttgt
     5161 taaggttcaa actaatctag gtgctactga taagatgaat gaatacatca ctcacatagg
     5221 tagtggactt tttacttgct ttggtggtgt ggagaaagga gactacattg gtcagaaatt
     5281 attggaaagc taggagctgg ttgcttgttt tagctttgtc atttttaatt ctttccccag
     5341 taggtgccca agaaagtttg agttcttatt tcgtaaaaat cacagatact tctaaagcgg
     5401 tcaaaaatgg caatcagtct gaggcccaga aacttgttca agagatggca tcagacttcg
     5461 aaagagtaga aaataaggat tctgaggttg gtaagattgt taaggaaaag ttagctctat
     5521 ctggagatat tactgaagcc aaactcaccg aaatttcctc agctctatta gcttttgaaa
     5581 aagaacaaaa tcctgttgac ctagatgcgg aaaaggaaaa attggtaaac cgtctaagtc
     5641 ctcgttttga aaccttagag caggccattg cctccaaaga tttggaaaaa gtccgagaag
     5701 cttttaagaa aatgaattcc acttggacca tcaatgaaag tgtggttcgt gacaatagta
     5761 tagctcatta tggacgtgtt gaaacagcta tttccttcct gcctagtagc atggaaaccg
     5821 aacctacaga tgagtctgga acatgaaaac agcagttgat ttcaagaaac aaaaaggaac
     5881 agccgaaact gttctcttat cattatttga gaccgtattt tttgttgaaa cgatccacgc
     5941 gtccatctgc ttgagtgaac ttttgacgtc cagtgtagaa tgggtgtgag tctgatgaaa
     6001 tttccacacg gatcaatggg taagtctcgc cttcgaactc aactgtttcg ttagagcgtt
     6061 ttgttgaacc gctaaggaat tggtaaccag tagttgtgtc catgaagaca actgggcgat
     6121 attctggatg gatatctttt ttcattttgc aatatttcct ttctgccatg gtctctttgc
     6181 gagccataga ttgttaccat actagtctat cagattctga aaagtttggc aagtatttta
     6241 tcagttttta agcaagtttt ttaacttttg gtagatgatt tcgttttcct ctaggctata
     6301 ggaattagca ccacttgcta gagggtggcc tccaccatca tgttccttgg caatttcatt
     6361 gataggatgg attttactgc gtaagcgaac gcggtagtgg ccatcagcct gttccacaaa
     6421 aattccccag agactaacac tatcaatacg cccaggtgca cttacaatgg ctgcagtttc
     6481 agcatcggtt acattgtatt gtttcaagac ttcttgactc aggataacgc gagcagcacc
     6541 attttcatcc acttccagat ggtcgtagat gtagccttgc agtttagcaa ttttgtagct
     6601 catagtgtcc attttgcgag tgagagccgc aaagtcaaag ttatgttctc tcaaataagc
     6661 agccaggcga agagtccgtg cagtggtaga agggtagagg aagcgacctg tatcaccgac
     6721 aattcctgca aagagcaact cagcatcgcg atctgccaag gctagttggg ttgtttgggc
     6781 aaatagggta atcatctcgc tagcgctact tgaactagta tcgacccaag acaggtcacc
     6841 gtatacatca tcatttggat ggtggtcaat cttaatgaga aaatcacctt gactatagcg
     6901 tttatcatcg atacgagcag tattagctgt atcacagacg atgacaagtg cgccttggta
     6961 ggccctatct tcaacaagat ccatctcagc catccaagta agagttggtt catcaaaacc
     7021 gacggctttg atggtttttt ctgggaaatg atgttccagc aaggctttca atcccacctg
     7081 acttcccaag gcatcagggt ctggtttcat atgacgatga atgataatgg tgtcgtattc
     7141 tttaattttt tctaaaattt gttggcaaat ctccataaat aacctcaatt ctttctcatt
     7201 tcattgtagc acaagaattt ttatttttaa aatgaaaaag atgtgatata atggagaaag
     7261 ataaattgag gaggacgata tggcattagc aaaaattgta tttgccagta tgaccggtaa
     7321 taccgaagaa attgcagata ttgtagcaga caaattacgt gacttgggct tggatgttga
     7381 tgttgatgaa tgtacaactg ttgacgcttc agacttcttg gaagcagaca tcgctatcgt
     7441 tgcgacctat acttatggtg atggtgaatt gccagatgag atgatggact tctacgaaga
     7501 cctagcagat ctcaacttga atggcaaaat ctacggagtg gtcggctcag gagatacctt
     7561 ctacgatgaa ttctgtaagg ctgttgatga ctttgaccgt gtctttgtgt caacaggagc
     7621 agaaaaaggt tcagagtgtg ttaaagttga tctttctgcc gaggaagaag atattgaacg
     7681 cttggaacaa ttcgcagaag aattggttgc taaagtagga taagcataaa agtgcgctga
     7741 tgtaatcaat cagtgcattt ttcttatcga gagttgggat tttactagcc taattgatgg
     7801 ctttttgata caataattca aataaaggag gagactgtat ggatttagat attattcgtc
     7861 aagaaatcga tcaaatcgac gaccaaattg tcaaactgtt agaagaacga atgcatttag
     7921 ttgagggggt ggttgcttat aagaaagctt caggtaaacc gattttagat actaagagag
     7981 aagaagttat ttttgaaaag gttgggagtc gtgtagagga caagcgctat caggagacta
     8041 ttgtagcgac tttttcggac atactcaaac gttcgcgtga ttatcaggat caaaatatca
     8101 aatgaaaaaa gaacaatttt atccgctagg aatttttcta gctgctatgt tgggcggact
     8161 tgtccgatat ctagtttcca cctggttacc agccagtcca gactttcctt ggggcactct
     8221 ctttgtcaac tatctgggaa ttttctgctt gatttatctt gtcaagggct atctggtcta
     8281 taaggggact agtaagggct tgattttagc actggggacg ggtttttgcg gaggtttaac
     8341 aactttttcc agcctaatgc ttgatactgt gaagctgctt gatacagggc gttatcttag
     8401 tttgatactg tatttgcttt tgagtatcgg tggaggcctg cttttagctt actatttggg
     8461 gaggaagaaa tggtaatcgt ctatcttgca atcgcctgtg gcttgggagc actcgtacgg
     8521 tatttctttt ctcgctataa tcaagtttct aaattgccac tcggaacgct catagctaat
     8581 cttttaggtt gttttttaat tggagtattc tacaatcatg tagagtctaa ggaagtatat
     8641 gctattctag caacaggatt ttgtggcggt ttaacaactt tttcgacctt gaatgacgaa
     8701 cttcaaagac tgctaagtga taagaaggtc ttttattctt acctgacttt gacttacata
     8761 ggtggtttgg ttgcgatttt tttaggaatt ttgctataaa tttctttact tttttttaga
     8821 aatttggtaa actgtatctt gtgtgtaatg gacgcacaaa aatacagttt atccgctgag
     8881 gaagattcct caagattgac aaagatagga gaataaaatg aatccattaa tccaaagctt
     8941 gactgaaggt caacttcgta cagatatccc atcattccgt cctggtgata ctgttcgtgt
     9001 acacgcgaaa gttgtcgaag gtaaccgcga acgtatccag atttttgaag gtgttgttat
     9061 cgcacgtaaa ggtgctggaa tctcagaaaa ctacacagtt cgtaaaatct ctaacggtgt
     9121 aggtgttgag cgtatcttcc caatccacac tccacgtgtt gaaaaaatcg aagttgttcg
     9181 ttacggtaaa gtacgtcgtg cgaaattgta ctacttgcgt gctcttcaag gtaaagcagc
     9241 tcgtatcaaa gaaatccgtc gttaattcga ctaaaaaact ctgcttttca gcagagtttt
     9301 tatctagctc ccttagttca atggatataa caactccctc ctaaggagta gttgcaggtt
     9361 cgattcctgc agggggcagt aattagatat caaagaagtt tgtcaaaaag tctttgatat
     9421 taaaagaacg cataatatag gggattgtct ccataatatt atgcgtttta ttattgaaaa
     9481 atttgggcaa tcatcagata aaattgagac tatatcgagt atataaatgt ttgtatagtc
     9541 aatttattca aaatcgtcaa gttctaaatt atttaaagga ctataacatt catatttctt
     9601 taagtaattg tttatttctt cagcagtgga acgaggtaaa ttaactctta aatagtcaat
     9661 atcttcctta gataaaaaat gatttgcatt caaaattgag aagcgaaata atgcttcatc
     9721 aaaagcaaaa tcataatcgt catcagataa tgattccatt aatgtttgaa tatgttttag
     9781 tgagtagtca ggtatcgaat cgggataata tactggataa tcagtggctg aaaaattgtt
     9841 ttctaatcct gaaatagtaa ttatcaaaga ttctatgtaa tatattaaag catgtttaat
     9901 attaccttct tgttccaaat gtcttccctg agcctttcgt gtgttagata agcatccaaa
     9961 atctcctgat acagtattcc tatgagcttg tttatttaag agactccatt ttatatcacc
    10021 aaaagttgct ttaaaagaga tattgttttt ttctttacaa taatcttcca tacttatgtc
    10081 tttatcatag tatgctttga tatagtcact atgttcgata ataagatttt gtgcttcttt
    10141 tgttagttta aattcgaacg gaatatctaa tttgtcaacg ttgatattat taattattct
    10201 tgtaattaat tctgcttttt ttccagaagt agctaaatta tgtttagata atatagtttt
    10261 taattctact actttaagat atgataaagt cttattttta gtgaagtatc ctaatttgta
    10321 taattgattg tgtgtagatt cagggtcaat ttgaagagag tatttaaaat atcttgggaa
    10381 attataattt ctccctgttt tttgagtcca atctatgagt atgagttgcc caggagtaag
    10441 gccgcactct aatttgttta ggtaaaaatt gttacaatca gaatttgtgt ctctattatg
    10501 attattttgt tttaaattaa atagtttgct aaaaaaattc attggatttt attgctaatc
    10561 aattcttatt gaaaaatgat acttttacag tacccatgta cggatggcat gggcaacgcc
    10621 agattcatca ttagatttag tgatgtattt ggcgattttt ttgatttctg gatttccatt
    10681 ttccatgaca acagggttgc caacgacttc cagcatggca cggtcatttt cttcgtctcc
    10741 gatagccatg gtttcatctt tggttaatcc tagtttttca gctaagtgag taatagctga
    10801 acccttgtct acattctttt taaggagttc gaggtagaaa ggagcagatt tgttgataga
    10861 gtagtgctcg taaaattcgg ctggtatttt ttcaatcgca gcatcgagaa tttctggttc
    10921 atcgataaac atacatttaa caatttcttt gccagccatt tcttcagggg tacggtagaa
    10981 gataggcatg ctgacgaggg ttgattcgtg tacagtgtat gttccgatat tgcgatttgc
    11041 agtatagata ccgtccttgg taatggcatg catgtggaca ccgagcttgc gactgaggaa
    11101 ttccatatcc agataatcct cataggtcaa ggattcgctg ataatctcat ggccagtagc
    11161 agtttcttgg acaagggcac cattgaaggt caccacatag tcaccttggt ctctcaactg
    11221 caagtcgtct agaagtttgg caacacctgc gatggggcgg ccagttgcaa tcacgacttt
    11281 gacaccagct tctttggcat cttggatggc agaaaagact tcaggagtga tttccttttg
    11341 gctgttgaca agggttccgt cgatatcaac ggcaattagt ttaatactca taaatttcct
    11401 cttctagttt ttatttgggg taaaatgatc gttctcaatc aagtataaaa attgctgggt
    11461 aatgctagca aagatactgt tttgatctaa catttctttc ggaaaataga aacgattatc
    11521 tccgtgacga ctaccagcaa gggattggac gataggagac aggctagaga gttcggccag
    11581 ttctccattc ttttgtaaaa tctcaatctg tgtccgtgga ttttcagatt cgggacgata
    11641 gatatcataa gggaggtcaa agttcttatg aatggcagta tagtagtcgg gatcaaagcc
    11701 aatgtcctca accaattttc tcatgctagc gagttggtct tgatcttctt gtgaaaaggt
    11761 aatggattta aagaccttgc ggttgacaaa gcgttgcgat aaatctgcga gaattttgtc
    11821 aggactggtc atccagagct ggaagtaggt attcatcaca ccatcatcta gagccagata
    11881 gtcagacaag gtcacatttt tttcaaagaa aggcaggagg tgtggggaag ttcgtgcaaa
    11941 gaagtctttg tccttagggt agagttcctt agcgcgcttg agaagattct gtaggagaac
    12001 ttccatagcg cgtgttgctg ggtggaaata gacctgcata tacatctggt agcgactgag
    12061 gacatagtct tcgatggcgt gcatgccatt gcgctgaaag gcgataccat tttcgatagg
    12121 acgaatgact cggaggattc gagtcaggtc aaattcccca taggatgctc ctgtaaaata
    12181 ggagtcacgc aagagatagt ccatgcgatc tgcgtcaatc tgactagaaa tgagttgtac
    12241 gacctgcttg ttaggatagg tatggtctat gacactggca actttctctg gaaaatcggg
    12301 cgctacttgt agcaagactt ggtgaatctc tgtctcagga ctttgaataa tctcctgagt
    12361 aatagcttca tggtctgtat caaagagatg ttcaaaagta tgggagtagg cgccatgccc
    12421 aaggtcatgt aggagagcag cgatcatggt caagagagac tcggcaggat tccattcctc
    12481 aggatatttt tcttcgaaaa tctctgtgat gcgtcgtgca atttcataga ctcctagaca
    12541 gtgagagaag cgactgtgtt ctccaccgtg gaaggtataa ctggaagttc ccagttgttt
    12601 gatccggcgc aaacgctgaa attcttttgt attaatcaag tcatagatga tttgattaat
    12661 gacatggatg tagttgtgaa ctgggtcacg gaatactttt tcgttcatat gaccattata
    12721 gcaaaatcct gctctttttg gtaaaatagt aggacaagag acaagaaaga gggcctgatg
    12781 tgaagattcg gatgcgaaat acaattcagt ttgatgagca gttggaagtg attgaccagc
    12841 tttatgatgt ggaagtgcat gaaaaaggag attatagcta cctgcttttc tataatgagg
    12901 aaaaggaaaa agtagtgatt aaatttcatg gtcaagaact tgtgatgagc cgattttcta
    12961 atcccaagac cattatgcgc tttctaaaga atagcgatag tttagcctat attcctacac
    13021 ctatgggcat gcaggagttt atcatccaaa cgagccatta tcaagttgat aggcaaaaga
    13081 ttgaactaga ttatcaacta caaaatcaag agggacatcc ttttgccagc tatcaattgg
    13141 aaattacttg gggctaggct catgtctttt tcaaatttag ctatctatct tcttggatcg
    13201 gtttcctagt gtggtagatt aggctaattt ttggtataat aaaagttatg gaaatcgaaa
    13261 aaaccaatcg tatgaatgcg ctctttgaat tttatgcggc gcttttgaca gataagcaaa
    13321 tgaattatat cgagctctac tacgctgatg attacagcct tgctgaaatt gccgaggagt
    13381 tcggtgtcag tcgtcaggct gtctatgaca atatcaagcg aacagaaaag attctggaag
    13441 attatgagat gaaattgcac atgtactcgg actatattgt ccgcagtcag atttttgatc
    13501 agattttgga gcgctatccc aaggataact ttctgcagga gcagatagaa attttaacaa
    13561 gcattgataa tagagaataa gaggaagaaa aatggcattt gaaagtttaa cagaacgttt
    13621 gcagaacgtc tttaaaaatc tacgtaaaaa aggaaaaatc tctgaatctg atgtccaaga
    13681 ggcaaccaaa gaaattcgct tggccttgct cgaggccgac gttgccttgc ctgttgtaaa
    13741 ggactttatc aagaaagttc gtgagcgtgc agtcgggcat gaggtcattg atacacttaa
    13801 tcctgcgcaa cagattatta aaatcgttga tgaggaactg acagccgttt taggttctga
    13861 tacggcagaa attatcaagt cacctaagat tccaaccatc atcatgatgg ttggtttaca
    13921 aggggctggt aaaacaacct ttgctggtaa attggccaac aaactcaaga aagaagaaaa
    13981 tgctcgtcct ttgatgattg cggcggatat ttatcgtcca gctgccattg accagcttaa
    14041 gaccttggga caacagattg atgtgcctgt ctttgcactt ggaacagaag taccagctgt
    14101 tgagattgta cgtcaaggtt tggagcaagc ccaaactaat cataacgact atgtcttgat
    14161 tgatactgcg ggtcgtttgc agattgatga gctcctcatg aatgagcttc gtgatgtgaa
    14221 agcattggct caaccaaatg aaatcttgct tgtcgttgat gctatgattg gtcaggaagc
    14281 agccaatgtt gcgcgtgagt ttaatgctca gttggaagtg actggggtca tccttaccaa
    14341 gattgatggc gatactcgtg gtggtgctgc tctgtctgtt cgtcacatta ctggaaaacc
    14401 aatcaagttc actggtacag gtgaaaagat tacggacatt gaaaccttcc acccagaccg
    14461 catgtctagc cgtatccttg gtatggggga tatgctcact ttgattgaga aagcttctca
    14521 ggaatacgat gaacaaaaag cccttgaaat ggctgagaag atgcgcgaaa acacctttga
    14581 ttttaatgat ttcatcgatc aattagatca ggtgcaaaat atggggccga tggaagactt
    14641 gctcaagatg attccaggta tggccaacaa tccagccctt caaaacatga aggtggatga
    14701 acgccagatt gctcgtaaac gtgccattgt gtcttcgatg acacctgaag agcgtgaaaa
    14761 cccaaatttg ttaaatccaa gccgtcgccg tcgtattgct gctggttctg gaaatacatt
    14821 cgtcgaagtc aataaattca tcaaggactt taaccaggct aaacagctca tgcagggtgt
    14881 tatgtctggg gatatgaata aaatgatgaa gcaaatgggg attaatccaa ataaccttcc
    14941 taaaaatatg ccaaatatgg gaggaatgga tatgtctgcc cttgaaggaa tgatgggaca
    15001 aggcggtatg cctgacttat cagctctcgg aggagcagga atgccagata tgagccagat
    15061 gtttggtggc ggtttgaaag gtaaaattgg tgaatttgcc atgaaacagt ccatgaaacg
    15121 tatggctaac aaaatgaaga aagcgaagaa gaaacgcaag taagacaaga gattgatgca
    15181 aatctcattt gatgagaaaa taaagtaaaa atttctatga taaaacgtat agtatcaagg
    15241 ttttagaata tctgatatta tacgtttttt gattttaata attttgttaa gacactttta
    15301 ttatggtatg cgaaaaatcc actcagctgt ctgagtggat taggtgtatt tagactctta
    15361 gtctttattt tcgtatggca agatcaagtt caagatgatt cctgtcatgg ctgaaagggc
    15421 agtacctgaa agtgtaactg gaccaagttt aaggatagct cctccaagtc caagaaccaa
    15481 catagcactt gcgatgatga ggtttcgcat ttgagcgaaa tcaacacgtt ctttaatcaa
    15541 gactttcaaa ccattgctgg cgataacccc atagagaagg attgacatac caccaagtac
    15601 agcgtttgga atagttgaaa tcaaggcagt gaatttacca aggaagctga gggcaatcgc
    15661 gatgaaggca gcgttacgga taactgagac agaagcgata cgagtcatac cgataacccc
    15721 tgtattttct ccgtaagttg tattggctgg tccaccaagg aaggcagaaa cagaagttgc
    15781 gataccgtca ccaagaagag tacggtgaag acctggttct tttaagaatt gacgaccaca
    15841 gatttgaccc aaaacagtat ggtctccgat atgttcagaa attgttacga tagcgattgg
    15901 caagatagcg atggcttctg gaccaaagta aagattgtac tctttaaagg caccacctgt
    15961 gctaaatggc aagtagaaac caggaatttc gaaccagttg gctttaagaa ctggtgtaaa
    16021 gtcaaccaag ccaagagtta gtgcgaaaag gtaaccaccg ataatggcaa agaggaatgg
    16081 aatgattcgt aggaagcctt ttccttttgt attgataaag gcagcaatta ggaaagtaac
    16141 aacggctacc agagcatttt tccaatttcc gtctgctaca agacctgcat tggtaacagc
    16201 tgaacctgca agtccaagac cgataacgat gatcatagga ccgataatga ttggtggcaa
    16261 gagtttatca atccattttg ttcctacaaa tcggatgctg gtagcaacaa ggacatagac
    16321 caaaccagtc aagataaccc ctgtttgggc agcagataca tcccccccca tttctttcat
    16381 agccagtgac atagctgtga taaaggcaaa tgaagaacct agataaactg gaactttaaa
    16441 accagtagca atcatgtaga tgagtgttcc aacacctgaa gcaaaaaggg caacagatac
    16501 aggcattccc aaaatcaatg gtaccaagat ggtcgcacca aacatggcga aaacgtgttg
    16561 gaagctaagg agaattcctt ttccatccga aggacgttgg tcaacgtcta gtaacaaatc
    16621 aacagttgat tcttgtttca tataaacctc acttttgggc atcagaaaag agcccattat
    16681 tttacagcaa taggccctca gagtaagact tctctaaaat ctagacttta aagagtttca
    16741 aatatttttg cgtcttcgtc acctcacggg atgacattaa aaacctttgc ttaggatagt
    16801 atagcagaaa aaaatgattt tgtaaatcat tttttcccga gcctagaaat aaaagagcga
    16861 ggctgatttt gtaaacattt gtttactaaa aaatttaaag tgggcgttta tttggcatac
    16921 cagccttacg tggatattta tttggtgttt cttttttctt ttctaccact gtgatatagc
    16981 gcggatctct attcggtagg gcgtagctga gattgtcttc gaccttacta aaaaggagat
    17041 tgagggcatt cttagcttct aataattcct caggcgcatt gctggccttg agtgccaata
    17101 gtttgccacc aaccttaagg tagggaatag tcaattcaga taggacctgc atacgggcaa
    17161 ccgcacgagc tgttacaaaa tcatattgag cacggaagtt cttgtcttgg gcaaaatctt
    17221 cggcacgtcc gtggtagaaa tgaactccgt tcaaatccag ttcttgagcc aagagttgta
    17281 ggaagttgat gcgcttattg agtgaatcaa taatggtcac atctaactcc ggatagagaa
    17341 ttttcattgg tagactagga aatcctgccc cagccccgat atcaagaagt ttgatagttt
    17401 cattgggaat caaaccttga agaatgggtg caatcgaatc gtaaaaatgt ttgagataaa
    17461 cttcttcctt gtccgtaatc gccgtcaaat taatcttctc attccactcg accaagagct
    17521 caaaataacg ttcaaattgt tctttttgct ggttcgaaag tggaagattc tgctcggcaa
    17581 gcaagttgta aaatgtttct ggtttcatag ttatttcctt ctttagtatc atcttatttt
    17641 accacaatca tagaaaattt gatatactgg tactaatcta aaagcagaaa ggacttatat
    17701 tatgacttgg attattcttg gagttatcgc tcttattgtt atttttgtga ttgttagcta
    17761 taacggtttg gttaaaaatc gtatgcaaac caaggaggct tggagtcaga ttgatgttca
    17821 gttgaaacgt cgaaatgacc tcttgccgaa cttgattgag actgtaaaag gttatgccaa
    17881 atatgaaggt tctacccttg aaaaggtggc agaactacgt aaccaagtgg cggcagcgac
    17941 ttcaccagca gaagctatga aagccagtga tgccctcact cgtcaggttt caggtatttt
    18001 tgcagttgca gaaagctatc cagatttgaa agctagtgct aactttgtta aattgcaaga
    18061 ggagttgaca aacacagaaa ataaaatttc ttactctcgt caactctata acagtgttgt
    18121 cagcaactac aatgtaaaat tagaaacttt cccgagcaat attatcgctg gaatgtttgg
    18181 atttaaagcg gcagatttcc ttcaaacacc tgaagaggaa aagtcggttc ctaaagttga
    18241 ttttagcggt ttaggtgact aagatgttgt ttgatcaaat tgcaagcaat aaacgaaaaa
    18301 cctggatttt gttgctggta tttttcctac tcttagctct tgttggttat gcggttggtt
    18361 atctctttat aagatctgga cttggtggtt tggttatcgc actgattatc ggctttatct
    18421 acgctttgtc tatgattttt caatcgacag agattgtcat gtccatgaat ggagcgcgtg
    18481 aggtggatga gcaaacggca ccagacctct accatgtagt ggaagatatg gctctggtcg
    18541 ctcagattcc tatgccccgt gttttcatca ttgatgatcc agccttaaat gcctttgcga
    18601 caggttctaa tcctcaaaat gcggctgttg ctgcgacttc aggtctacta gctatcatga
    18661 atcgtgaaga actagaagct gttatgggac atgaagtcag tcatattcgt aattatgata
    18721 tccgtatttc gactattgca gttgcccttg ctagtgctat caccatgctt tctggtatgg
    18781 caggtcgtat gatgtggtgg ggtggagcag gtcgcagacg aagtgatgat gaccgagatg
    18841 gaaatggtct tgaaatcatt atgctagtgg tttccctact agctattgta ctggcacctc
    18901 tcgctgcaac cttggttcag ctcgctattt ctcgtcagag ggaatttctg gcagatgcat
    18961 ctagtgttga gctgactcgc aatccccagg gaatgattaa tgccctagat aagttggaca
    19021 atagcaaacc gatgagtcgc cacgtcgatg atgctagcag tgctctttat atcaatgatc
    19081 ccaagaaagg tggggggttc caaaaactct tttataccca cccacctatc tcagaacgga
    19141 ttgaacgttt aaaacagatg taaaagaatc cagaggtcgt ctctggattt ttgctatgtt
    19201 gcaaatttat aaatcttcta aattaactaa ctccaaaccg tgttctgtca tgcgatagat
    19261 gatcgagcag acttctttta agaaacgacg gtcatgcgaa acagtgatga gaccgcctgg
    19321 ataggttgca aagagttttc tgatttgggg ttgagaagtg ggagaaaagt ttcgtgtggg
    19381 ttcatccagc aggagaaagt ttggtttgcg caggactaga tccaaaagca ggagttttcc
    19441 ctgttgtccg ccagataagg agcgaatttg atgctgcatt tctggataac tgaaattgag
    19501 actggctagg tgagagtgga ttttctgaag ttcctctttt tccccagttt tgctgatata
    19561 agctattggt gataaatcca attgtagttt tttgtggtaa tcttgtggca taaaaccaag
    19621 ggaaatctct cttttatcat tcagaagttg ctttaatttg gctaacagag ttgatttccc
    19681 aacaccattt ggcccgataa taccgatttt ttcttgccca cggacagtta gttgtagttt
    19741 ttgaaccaaa actcggtcgt caatggacaa attttctttt tccagttgga ctaagacttt
    19801 agaagctggt aatggttgga tgtctgaaaa gaaaagttgg atttgttcct cttcaagtgg
    19861 tttttgagtc atggactgag ctgccttttc gtagcgtttt tcttgtgaga ggacagtttt
    19921 catcttttta gccaataggc gaccggcagt actatctttg gtagctcgaa gcgcagtttc
    19981 tacattttgc ttaactctcc gatgtttttc catggtttta tcgtaggctc tttggttgtt
    20041 agcagcttgc tgactttgtt tggcaaaatt agcctttctc tgctcactat agctatcata
    20101 gtctaaatgc tctactagcg tttccgcttc tttacggtgt ttgaccagtc gcaagtgaac
    20161 aatagtgtct gccgtttcag aaagaaagtc ttcatcatgg gaaatgaaaa taacggtttg
    20221 cctggtcttt tgaatctggc cttttagcca atcaactgtc tcaaggtcta ggtcatttga
    20281 aggttcatct aaaaatagaa tctcaaaggg tttggctaac tcatggataa gctgaatttt
    20341 caaagcttct ccccctgata gattgccaat ctcttggtca cttgcgaaac gattgctatc
    20401 aaaatgcaat tcctccgcca aacgatagag gatactgtag tctaaatcaa tagaatctaa
    20461 aaagaagtag tcgtgtaaag ttttcttttt cagctcctcg ggaagttttt gaggaatgta
    20521 ggccagtgac tgatagtcag attggatgtt tcccttgata gtgaaatcag acaaagcttc
    20581 ccccattaaa gttttaagta aggttgattt accatttcct tcttcgccaa taatagctac
    20641 cttttccccg tcttgtatgg tcatgcttag gtcagagaca aggtctcgta aatctttgtt
    20701 ttgtgtgatg gtcaggtgat tgatttttat catactattg ccctttctag aatgttcata
    20761 gtgcataaca aaaagctcta ctttacctag tagagcccaa agtctatgtc aaaaaaactc
    20821 tattaacatg ccagaaaaag ggcataaaag agcacacaaa aagagacaaa aacaagatct
    20881 actaaataaa ggttctttat ttgatagact tagttgttca tgtctccctt acctcctagt
    20941 attagtatct ttatactata cttttaagga aattttgtca acagaaaact ggaaattcta
    21001 tgctctaaaa tccaaaaaca ggtctataga gacttagtac gtgtttgaca tgctcgtaat
    21061 ggattttatc atagtttcgc caagcagtgc gttcttgatt gtttagtttt aggctaccca
    21121 gtccaatcat aggactggtg ggttggtaaa atttctcaag atcaattaag atactgttgt
    21181 tcaacttttc cgttttttga gttcttgcat agtagtgttt agcagctctt gtagtcgaat
    21241 atcatctgcc gtaccctgtt tacagttttg gtagctttta tttaacttgg ataggagttg
    21301 aatgagtttc ttgtcttccg tgtgagcatc ctccttgatc tgatgtactc tttccctata
    21361 gtatagcact aaaaaataaa actgtcatag tgaatatgtt aaaatttcga attttaatta
    21421 caaagtttgg tgtgctgatt tgtagccttt tcatggtata atcaagagag taaatcttta
    21481 tggaggaagt atgaaattaa atattcaaga aattcgtaag cagtctgaag gtttgaactt
    21541 tgaacaaacg ttagatttag ttgatgacct gcgtgcacgt aatcaagaaa ttttagatgt
    21601 aaaagatatc cttgcagttg ggaaagtaca atatgaagac cgtatgtatt tcttagatta
    21661 tcaactatct tataccattg ttcttgcttc gagtcgcagt atggagccag ttgagttagt
    21721 tgaatcttat ccagtcacgg aagttttcat ggaaggcgca actaaccagc tagatcaaga
    21781 agttttagat gatgacttgg tcttgcccat cgaaaatggg gagcttgacc ttgctgagag
    21841 tgtatcagac aatatcctgc taaacattcc tatcaaggtc ttgacggctg aagaagaagc
    21901 tggtcaagga tttgtctcag gaaatgactg gcaaatcatg acagaggaag aataccaagc
    21961 tcaacaagca gtaaagaaag aagaaaacag tccttttgct ggcttacaag gactatttga
    22021 cggagatgaa taatggtctt gtcaaaaaaa cgagcacgaa aggtgctaga agaaatcatt
    22081 gccctcttcc cagatgccaa gcctagtctt gattttacca atcattttga actcctggtt
    22141 gcggtcatgt tatcagccca gacgacagat gcagcggtaa ataaggccac accaggtctc
    22201 tttgttgcct ttccaacacc ccaagctatg tctgtagcga cagagagtga gattgcttca
    22261 catatttctc gcttgggatt gtatcggaat aaagctaaat tccttaaaaa atgtgcccaa
    22321 cagttactag acgattttga tggtcaagtc cctcagacac gtgaagaatt ggagagtttg
    22381 gcaggtgttg gtcgcaagac agccaatgtt gtcatgagtg taggatttgg gattccagcc
    22441 tttgcagtgg atactcatgt ggagcgtatt tgcaaacacc acgatattgt caaaaaatca
    22501 gcgacgccac ttgaggtgga aaagcgggtc atggatatct tgccgcctga gcagtggtta
    22561 gctgcccatc aggccatgat ttattttgga agagccattt gccatccaaa aaatccagag
    22621 tgtgaccagt acccacaatt atatgatttt agcaatttgt aagatgctac attgaaactt
    22681 tttgcttgat tttaagcatg ctttgtgcta tagtaaatga taactaaata ttcctttaaa
    22741 cctgtcccgt gaggcaggca aggagcgcga taaagtagaa gggtgaagtc tatactgtgt
    22801 gcagtagggc tcgcttggct ataaatttca agtctccttg tttaaggaga cttttctttt
    22861 tggaggtttg tcatgaaaac aaaagaagtt gtagacgaat tgaccgtcaa acgagcgatt
    22921 acgcgtatta cttatgagat tatcgaacgc aacaaagatt tgaataagat tgtcttggct
    22981 ggtattaaaa ctcgtggtgt ctttattgcc caccgaatcc aagaacgttt gaagcagtta
    23041 gaaaatcttt cagttcctgt tgtggaattg gatactaaac ctttccgtga tgatgttaaa
    23101 agtggagaag atacttcttt ggtttctgtc gatgtgacag accgcgaagt tatcttggtg
    23161 gatgatgtgc tctatacagg tcgtaccatc cgtgctgcta ttgataatat tgtcggtcat
    23221 ggtcgtcctg cgcgtgtgag tttagcagtt ctagtcgatc gtggacatag agaattgcca
    23281 atccgtccag attacgttgg aaaaaatatc ccaaccagtc gttctgaaga aatcatcgta
    23341 gagatgacag aacttgatga ccaagacaga gttctgatta ctgaagaagc ttagaaagtt
    23401 aaaggagtag ccatgtcaga aaatcaacaa gcattgaacc atgtggtgtc catggaagac
    23461 ctcactgtcg atcaagtaat gaaattgatc aagcgaggaa ttgagtttaa aaatggagcc
    23521 cagcttccct atgaagacca tccgattgtt tccaatctct tctttgagga ttctacacgg
    23581 acacataagt cctttgaagt cgcagagatt aaacttggat tggaacgact tgactttgat
    23641 gtgaagacta gttcggttaa taagggtgag acactttatg acaccatttt gactctgtct
    23701 gctttaggag tggatgtctg tgtgattcgc catccagagg tcgactacta tagagaattg
    23761 attgctagtc caacgattac gacttccatc atcaatggtg gagatggttc gggccaacac
    23821 cctagccaga gcttgcttga tttgatgacc atttatgagg aatttggcca ctttgagggt
    23881 cttaaagttg ctattgcagg tgacttggac cactcacgcg ttgccaaatc caatatgcag
    23941 attttgaaac gcttgggatc tgaactcttt ttcgctggac ctgaggaatg gagaagtcaa
    24001 gagtttgcag actatggaca gtttgtaacc attgatgaaa tcattgatca ggttgatgtc
    24061 atgatgtttc tccgtgtgca acacgaacgc catgatagtg gagctgtatt ttcaaaagaa
    24121 gactaccatg cccaacatgg cttgactcaa gaacgttacg atcgtttgaa agaaacagca
    24181 atcctcatgc acccagctcc aatcaatcgt gatgtagaaa tagcagacca cttggttgaa
    24241 gcaccaaaat cacggattgt ccaacaaatg accaatggtg tctttgttcg aatggcaatc
    24301 ttagaatccg tactagcgag tagaaacgcc aactaaaaca caagacgtta aaagacgcca
    24361 gtgagcgtcc acgagaggtg aaaatatgac aaaaagaatt ctagtattag aagatggcac
    24421 agtttttgaa ggcaaggcct tcggagcaga tattgatgta acaggcgaaa tcgtctttaa
    24481 tacagggatg accggctacc aagaatccat tacagaccag tcttataatg gacaaatctt
    24541 gacctttact tatcctttgg tcggaaacta tggaattaac cgtgatgatt acgaatctat
    24601 tattccaact tgtaagggag ttgttgtttt cgaaaaagcg cgtagagcaa gcaactggcg
    24661 caaccaaatg accttggatg aatttttgaa agccaagaaa attcctggta tttcagggat
    24721 tgatacgcgt gcacttacca agattattcg taagcatggt actatgcgag caaccttgac
    24781 tcatgttgga gatagtatgg accatgtgac tgaccagctc caagcaacag tattgccgac
    24841 agataatatt aagcaggttt ctactaaaac ttcctatcca gctccaggag ttggtttgag
    24901 cgtggtgtta gtagactttg gtctcaagca ctcaatccta cgtgaacttt ctaagcgcaa
    24961 ctgtaatgtg acggttgttc cttattcgac aacggctgaa gaaattctcc atctcaatcc
    25021 tgacggagtg atgttgtcaa acggtccagg taacccagaa gatgttccac aggcactgga
    25081 tatgattcgc ggtgtacaag gaaaaattcc aatctttggt atctgtatgg gacatcaact
    25141 ctttgctatg gcaaacgggg ctaagaccta taagatgaag tttggccacc gtggattcaa
    25201 ccatgcggta cgtgaaatcg caacaggacg agtagacttc accagccaga accatggtta
    25261 tgcagtcagc cgcgaggatt tgccagagca cttgattatt acccacgaag aaatcaatga
    25321 caagtcagtg gaaggtgtgc gccacagata ccaacctgct ttctctgttc aataccaccc
    25381 agatgcagct cctgggccac acgacgctag ctacctattt gacgagttta tcgagatgat
    25441 ggaagttttt aaacaatcaa actaagaacg agtaaaagct cgtcggagaa tttatgtaac
    25501 tgaacacgga cggaaagctc agaatttaga gaaaccaact tggattgtca atccttcctt
    25561 gatttcttaa aattcaatcg ctttctattc gtcctttgta tcttatttaa tgtcgccctg
    25621 agaggcgacg aatagaaagg agaagggtgc tccgtatttg ctgaactgaa tacgggctac
    25681 ggacggtgct aaaaagatag ttattcctag aactgacagt tcttcgtcat aactcctatt
    25741 ttagctttgt ccgcttgacg cccttaatat cttatatatg cctaaacgta ctgatattca
    25801 aaaaattatg gtgattggtt ctggtccgat tattattggt caggctgctg agtttgacta
    25861 tgctgggacc caggcttgct tgtcgttgaa agaggaaggt tatgaggttg ttttggttaa
    25921 ctcaaatcct gcaaccatca tgacggacaa ggaaattgct gacaaggttt acattgaacc
    25981 gattacactt gagtttgtga cacgtattct tcgtaaggaa cgtccagatg ccttgctacc
    26041 aacactcggt ggtcagacag gtctcaacat ggccatggaa ttgtctaaaa atggtatctt
    26101 agatgagctt agcgttgaac ttctgggtac taaattgtct gccattgacc aagcggagga
    26161 ccgtgacctc tttaaacaat tgatggaaga gcttgagcaa cccattccag aatctgaaat
    26221 tgttaacaca gtagaagaag cagttgcctt tgcagcgaca attggctacc cagtcatcgt
    26281 tcgtccagcc tttacccttg gtggtactgg tggtggtatg tgtgccaacg agaaagaatt
    26341 gcgtgaaatc actgaaaatg gtttgaaatt gtcacctgtt acccaatgtt tgattgagcg
    26401 ttcgattgct ggtttcaagg aaattgaata cgaagtgatg cgtgactcag ctgacaatgc
    26461 cttggttgtt tgtaacatgg aaaactttga cccagttggg attcacacgg gggattccat
    26521 tgtatttgcc cctgcgcaaa ccatgtcaga ctatgaaaac caaatgcttc gtgatgcgag
    26581 cttgagcatt attcgtgccc tcaagattga aggtggatgt aatgttcagc tagctcttga
    26641 tcctaacagc ttcaagtatt atgttatcga agtaaaccct cgtgtatcac gttcgtcagc
    26701 ccttgcttct aaagcgacag gatatccgat tgctaagttg gctgccaaga ttgcagtagg
    26761 tttgaccttg gatgaggtta taaacccagt tacaggttca acctatgcca tgtttgaacc
    26821 agcccttgac tacgtagttg ctaagattcc acgtttccca tttgacaagt ttgaaaaggg
    26881 tgaacgccgt ctcggtacac aaatgaaggc gactggagaa gtcatggcaa tcggtcgtaa
    26941 catcgaggaa tctcttctca aggcctgccg ctcccttgaa attggggtgc accacaatga
    27001 aatacctgaa cttgcagcag tttctgatga tgccttgatt gaaaaggttg tcaaagccca
    27061 agatgaccgt ctcttctacg tatcagaagc aattcgtcgt ggctacacac ctgaagaaat
    27121 tgcagagctt acaaaaattg atatcttcta tcttgataaa ctcttgcata tctttgaaat
    27181 tgagcaagaa ttgggtgctc atccacaaga tctagaagtt ttgaaaacag ccaaacttaa
    27241 tggtttttca gaccgtaaga ttgctgaact ctggggaacg actgatgata aagttcgcca
    27301 acttcgcttg gaaaacaaga ttgttccagt ttataagatg gtagacactt gtgcggcaga
    27361 gttcgactcc gaaacgccat atttctattc aacctatggt tgggaaaatg aatctatcag
    27421 atctgataaa gaatctgtac ttgtcctagg ttcaggtcca atccgtatcg gtcaaggggt
    27481 tgagtttgac tacgcaaccg ttcactctgt taaggctatc caggcagctg gttatgaagc
    27541 tatcatcatg aactcaaacc cagagaccgt ttcaacagac ttctctgtat cagataagct
    27601 ttactttgag ccattgacat tcgaagatgt tatgaacgtc attgacttgg aacaaccaaa
    27661 gggagttatc gttcagttcg gtggtcaaac agccatcaac cttgcggagc cattggcaaa
    27721 agcaggtgtg accatccttg gtacacaggt tgctgaccta gaccgtgccg aagaccgtga
    27781 cctcttcgag caagctctca aagaattgga tattccacag ccaccaggac aaacggctac
    27841 caatgaagaa gaagcagctc ttgcagctcg taagattggc ttcccagttc ttgtccgccc
    27901 atcttatgta cttggtggac gtgccatgga aatcgttgaa aacgaagaag accttcgttc
    27961 ttacatgcga actgctgtta aggctagtcc agatcaccca gttcttgtcg actcttatat
    28021 cgttgggcaa gagtgcgaag ttgatgccat ttcagatggt aaagatgtgc tcattcctgg
    28081 tatcatggag catatcgaac gtgctggtgt ccactcaggt gactcaatgg ctgtttaccc
    28141 accacaaacc ttgtcgcaaa aggttcagga gaccatcgca gactacacca aacgcttagc
    28201 aatcggtctt cactgccttg gaatgatgaa catccagttt gttatcaagg atgaaaaagt
    28261 ctacgttatt gaggtcaatc cacgtgccag ccgtactgtt ccattcctat ctaaggtaac
    28321 caatattcct atggctcaag tagcgaccaa gctcattctt ggtcaaagtt tatcagaact
    28381 tggctaccaa aatggacttt accctgaaag cacccgtgtt catatcaagg cacctgtctt
    28441 ctcctttacc aaactagcta aggtagacag cttgctcggt cctgaaatga agtcaacagg
    28501 tgaagttatg ggttctgatg ctactttgga aaaagctctc tataaagcct ttgaagcttc
    28561 ttatctacac ttgccaactt ttggtaatgt cgtctttacc atcgctgatg atgccaaaga
    28621 agaagccttg aacttggctc gtcgtttcca aaacattggt tatggaatcc ttgcgacaga
    28681 agggacagca gccttctttg ctagtcatgg cttgcaagcc caacctgttg gtaagattgg
    28741 tgatgacgat aaggatatcc caagttttgt acgcaaagga agaattcaag ctatcattaa
    28801 cacagtagga acaaaacgaa ctgctgacga agatggtgag caaattcgtc gttcagccat
    28861 tgaacacggg gtgcccctct tcacagcgct agatacagct aatgccatgc ttaaggtact
    28921 tgaaagtcgt agctttgtta cagaagcgat ttaaatagaa aaataagata tagcagactg
    28981 aatttagaac agtacacagg aatactaaaa tatttctata aattaatttg aattttctaa
    29041 ttgatttgtt cgcatcttat ttcaatctac tatagaaaaa agtctttaaa attataaaac
    29101 gcatcatatc aaggtttttc aaaaaccttg atatgatgcg ttttattgtg ggaatatgta
    29161 tttcattttc tactaaaatt atgtttttga ataacctcta tcttagtagt ttgtataatc
    29221 cccctcaatc agtttttgcg ataagcttta atgctatgac tataccactc ttgcatttct
    29281 tttgatggtg gtgtcatata atcgccatac atctgggtta aaaattggtc atattttttg
    29341 ggaacaggca acatacggcc ctcaaactca gttaaaatca gttctttaaa ggtatcaact
    29401 gggaagattt ctttcatccc ttccttaccg atcccaactc ctccttcata ttgaggaatg
    29461 ttggttacag catttttgac tagttgatca attttcttgt aaaagtagcg aggattgaca
    29521 aatcggagag cgtaccagct acataatcta agaaaatctt ttagtttgct atcaccgtga
    29581 actgctcgtg attttttgat ataagctagt tgacgaagag ccacatactt atagctcttg
    29641 tcgacaatgc tcaagtctgt aaatcgatca attgggaaga catcgatgaa aaggctggta
    29701 tcatgacgct tgtacttaac atggtcttct ataacagtag aagtgtccaa aatcgatgcg
    29761 aaattatgga agtaccaaga agatgtatcg taggaaagaa ccttgtagcg agggtgattt
    29821 tcttcttcaa taatcttcag taaacgctca taatcctcac gataaaggga aatatcaata
    29881 tcatcatccc aaggaatcat acctttgtgg cggatggctc caagcatggt tccataactg
    29941 agaaaataag gaatatcatg tttcttacaa gtctcatcaa tatagtccag cagggctagt
    30001 tgaatttctt taatttcttt tttttctaaa tattgcatcc taatcctcca atttataagc
    30061 gtgaaattca tgactgtaga agcgtttttc ttctggtggt agggtcatat aatctccata
    30121 aaattgtgtc aaaatagtat caaatttttc aggtgcagga aggcttaaat tctcaaaggg
    30181 taaatcgatt gttttatcaa aggtaccact tgggaagact tccttttcct taaattttga
    30241 agggataaaa gccatatact gcccattttc acgactatat ttttgaattt ctttctcgat
    30301 tttatttgca aaataacgag gagaaactgg tcgaaggagc aaccaaaagg ctgttcgtat
    30361 ccaatctttt aaaaggctat ccttatagac aatattttta tgtttactga aagacagcag
    30421 tttgaagctt tccagtttat aacaagtatc aatgacctta ggatcatcaa agcgatctat
    30481 agggaaaata tcgataaaga taccagactc ataggttttt gtatttcgag tatcaataat
    30541 tttagtcgta ctgtcggtta tcttgataaa gttgttaaag tagttcttat cagtttctaa
    30601 ggataggagc ttatacttgc ttttttcctt ttgaaaaatg ttaataaatc gttggtagtc
    30661 ttctctaggc atggataaat caatatcgtc gtcccaaggg ataaagccct catgtcgaac
    30721 cgccccaatc agagtaccgt agttaataat atagttgata ttgtgctttt tacagagagt
    30781 atcaatataa tccaaaattt ctaattcaat ttgtttggca tcttcaatgg ttagttgttt
    30841 cattttaaac tcctatgatt ttttgaattt attttttaag gctaggacat ggtttaaaaa
    30901 ttcatagaaa atgctatctt ttgtgaagac aagtagacta atataagaga tagctgatag
    30961 caagacaatc aaaccagtat taattaaaaa tggcaaatta atgaccatat ccacaggata
    31021 cacgaaatta atcaggaaat aaattgctac aaaggaaagt gaaaagagag agtatcgaac
    31081 agtatagcta aagatatgtc ccaagtggat gagttgtttt ctatggatga aaataatata
    31141 gaaaacaagt agagaagtct ctgataacat agttgtcagt aagtagtatt caggaaccac
    31201 gatatggttg aaaaagagga gactattcaa gcccaaattg agtagcccag caaagactgt
    31261 atagactgtg atacgttttt catagccatt ggtaaagaga atttgggaac caagaatggt
    31321 atctaaggcc aggataatcg tacgaaaagc gaagagagag gtcaagatgc cgcctccgat
    31381 atatttttca ctaccgtaaa gtaggatggc atttggtcct aaaaccatga gtccaaaact
    31441 cagtggaatg ataaagaagt taaagattcg actacctcta ttaaccagag aaacataggc
    31501 ttctttgtct cctttcccca gatagtaact gagacgaggc acactcactc caattgcacc
    31561 tgttacaacc ccagctataa cggtcacaat tcgctgagct atggtatagt aactaacgtt
    31621 gacatcaatc cctgttttaa cgaggaagag gcgatctaaa aaagtgaaga gcatattggc
    31681 attggcaaag actaacatgg ctgtcagagg gagaaagagt ggtttaaaat cacttaggtg
    31741 aatcttaaca agtttgatgt ctcttttaat ccaaaaataa ctaatcaggt agttaatcag
    31801 cgtcgataaa ctcatcacaa gtgtatagac aacaatatcg tgttcatttt taacaaataa
    31861 gaaaatagag accagcatca ggatacggat gaaggcagtt ttgtaaaaga gaaaactgta
    31921 attttccaga gcttcattga cccattcgat tgaaaaaatc tgggcaatga gttgaatccc
    31981 cataacaagg tagacctttt tgacgattgg attatcaata aagaagagag gataggctag
    32041 gatatagaca gcagtggtca aaatcgtaca agcgatgcac aaataaaaaa gactagaaaa
    32101 ggttctgtta agatcttttt tgttatcctt gacattactg atagccctta aaccgtagtt
    32161 atagacacca taagttgcaa agggcaagaa aaatgacaaa atagtgtcga ctgagttgaa
    32221 gtaaccatag tcagttcggt ccaagacacg cgcgacatag gttccagtta ggatgggaaa
    32281 aataatattc aagacacgaa ttcccatgta agatagagca tttaatttta tacttttcat
    32341 tcaatttacc tcgtttttca ttatatcata aagttagcta ataagaaatg aagggcagta
    32401 agtcaagtaa tcactttgaa gtttcaaatc ttaagtttta agttttcttt aaggaaagta
    32461 tattattctg aaggactcta aaatttcgca gccatttatt agtaattgct acagaattcc
    32521 tagtcattac tagaaatgga ctagtttctt tgaataatag aactgcataa ttctcctatt
    32581 ctagaagggg aggaccagta tttcttttat gataggacta gattgtggta taatagagag
    32641 aataagtttt tttagtaaga caaaggagaa aatagatgat ttatgcagga attcttgccg
    32701 gtggaactgg cacacgcatg gggatcagta acttgccaaa acaattttta gagctaggtg
    32761 atcgacctat tttgattcat acaattgaaa aatttgtctt ggagccaagt attgaaaaaa
    32821 ttgtagttgg tgttcatgga gactgggttt ctcatgcaga agatcttgta gataaatatc
    32881 ttcctcttta taaggaacgt atcatcatta caaagggtgg tgctgaccgc aatacaagta
    32941 ttaagaaaat cattgaagcc attgatgctt atcgtccgct tactccagag gatatcgttg
    33001 ttacccacga ttctgttcgt ccatttatta cacttcgcat gattcaggac aatatccaac
    33061 ttgcccaaaa tcatgacgca gtggacacag tggtagaagc agttgatact atcgttgaaa
    33121 gtaccaatgg tcaatttatt acagatattc caaatcgtgc tcacctttat caaggacaaa
    33181 cacctcaaac attccgttgc aaggacttca tggaccttta tggatctctt tctgatgaag
    33241 agaaggaaat cttgacagat gcatgtaaaa tctttgtgat caaaggaaaa gatgtggcct
    33301 tggccaaagg tgaatactca aatctgaaga ttacaaccgt aacagatttg aagattgcaa
    33361 aaagtatgat tgagaaagac tagtaaaatg attaatcaaa tttatcaact aactaagcct
    33421 aagtttatca atgtcaaata tcaggaagag gctattgacc aagagaatca tatccttatc
    33481 cgtcccaact acatggctgt ctgtcatgcg gatcagcgtt actatcaggg aaaacgtgat
    33541 cccaagattt tgaataaaaa gcttccaatg gcaatgattc acgagtcatg tggaaccgtc
    33601 atttctgacc cgaccggaac ctacgaggtt ggtcaaaaag ttgtcatgat tcccaatcag
    33661 tctcctatgc agagtgatga agaattctat gaaaactaca tgacagggac ccatttcttg
    33721 tctagtggat ttgatggctt tatgagagag tttgtttctc tccctaaaga tcgtgtggtg
    33781 gcttatgatg ctattgaaga tacggttgca gccattacag agtttgtcag tgtgggcatg
    33841 cacgctatga atcgtctatt gactcttgct catagcaagc gggagcggat cgccgttatt
    33901 ggagatggaa gtttagcttt tgtggttgcc aatattatca actatacttt gccagaatca
    33961 gagattgtgg ttattggtcg tcattgggaa aagttggaac tcttctcatt tgccaaagaa
    34021 tgctatatta cggataatat tcctgaagag ttggcctttg accatgcttt tgaatgttgt
    34081 ggtggtgatg gtactggacc agctattaat gacttgattc gctacattcg tcctcaggga
    34141 acgattctca tgatgggagt tagcgaatat aaagtcaatc tcaatactcg cgatgcctta
    34201 gaaaagggct tgattttggt tgggtcatct cgttctggtc gcattgattt taaaaatgct
    34261 atccaaatga tggaagtcaa gaaatttgcc aatcgtctta aaaatatcct ttatctagaa
    34321 gaacctgtaa gagaaattaa agatattcat cgtgtctttg caaccgattt aaacacagcc
    34381 tttaaaacag tgtttaagtg ggaagtataa gtactggagg ttaattgtgg agaaaatcat
    34441 taaagaaaaa atttcttcct tacttagtca agaagaggaa gtcctcagtg ttgaacaact
    34501 gggtggaatg accaatcaaa actatttggt caaaacaaca aataagcaat acattgttaa
    34561 attctttggt aaagggacag aaaagcttat caatcgacaa gatgaaaagt acaatcttga
    34621 actactaaag gatttaggct tagatgtaaa aaattatctt tttgatattg aagctggtat
    34681 caaagtaaat gagtatatcg aatctgcgat tacgcttgat tcaacgtcaa tcaagaccaa
    34741 gttcgacaaa attgctccaa tattacaaac tattcataca tctgctaagg aattaagagg
    34801 agaatttgct ccttttgaag aaatcaaaaa atacgaatcc ttggttgaag aacaaattcc
    34861 ttatgccaac tatgaatctg ttagaaatgc agtcttctcc ttagagaaaa gactggctga
    34921 cttaggtgtt gacagaaaat cttgtcatat cgatttggtg cctgaaaact ttatcgaatc
    34981 acctcaagga cgactttatt tgattgactg ggaatattca tcaatgaatg atccaatgtg
    35041 ggatttggct gccctctttt tagagtctga attcacttcc caagaggaag aaactttctt
    35101 atctcactat gagagtgacc aaacaccggt ttctcatgaa aagattgcta tttataaaat
    35161 tttacaagat actatttgga gtctatggac tgtatataag gaagagcaag gtgaagattt
    35221 tggtgactat ggtgtgaatc gttaccaaag agctgttaaa ggtttggctt cttatggagg
    35281 ttcagatgaa aagtaaaaac ggagttcctt ttggccttct atcaggtatt ttctggggct
    35341 tgggtctaac ggttagtgct tatatctttt cgatttttac agatttgtca ccctttgtgg
    35401 tggctgcagc tcatgatttt ttgagcatct ttatcttact agcttttctc ttggtaaaag
    35461 aagggaaagt tcgcctctca attttcttaa atattcgcaa tgtcagtgtt atcatcggag
    35521 ccttgctagc aggccctatc ggtatgcagg ccaatcttta tgcagttaag tatatcggaa
    35581 gttctttagc ttcatctgta tcggctattt accctgcgat ttcagttcta ttggctttct
    35641 tctttttgaa gcacaagatt tcgaaaaata ctgtatttgg gattgtcttg attattggag
    35701 ggattattgc ccagacctat aaggttgaac aggttaattc cttctacatt gggattctct
    35761 gtgctttggt ttgtgctatt gcatggggaa gtgagagtgt tcttagctcc tttgctatgg
    35821 aaagtgaact gagtgaaatc gaagccctct taatccgtca agtgacttcg ttcttgtcct
    35881 atcttgtgat tgtgctcttc tctcatcagt catttactgc agtagccaat ggacaattgc
    35941 taggtctcat gattgttttt gcagcctttg atatgatttc ctacttggct tattatatcg
    36001 ctatcaatcg cttgcaacca gccaaggcta caggcttgaa cgtgagctat gtagtatgga
    36061 cagtcttgtt tgcagttgtt ttcttgggtg caccgctaga tatgctgaca attatgacgt
    36121 cacttgtcgt cattgctgga gtttatatta ttattaaaga ataaaggaga ttcgtgtgaa
    36181 agccatcatc ttagcagcgg gattgggaac tcgcttgcgt cctatgactg aaaatacccc
    36241 taaagccttg gttcaggtta atcaaaaacc tttgattgaa taccaaattg agtttctcaa
    36301 agaaaaagga atcaatgaca tcatcatcat tgttggttat cttaaagaac aattcgatta
    36361 cttgaaagag aaatacggtg ttcgtctcgt tttcaatgat aaatacgctg actacaataa
    36421 cttttactct ctctatcttg taaaagaaga attagccaat agttatgtta tcgatgccga
    36481 taactatctc tttaaaaata tgttccgcaa tgatttgaca cgttctactt attttagtgt
    36541 ctatcgtgaa gattgtacca acgaatggtt cttggtctat ggagatgact acaaggttca
    36601 aaacattatt gttgatagca aggcaggtcg catccttagt ggtgtatcct tctgggatgc
    36661 tccaacagca gaaaagattg tcagctttat cgataaggct tatgcaagcg gcgaatttgt
    36721 tgatctctat tgggacaata tggttaagga taacatcaaa gagctagatg tctatgttga
    36781 agaattagaa ggcaatagca tttatgagat tgatagtgtc caagactatc ataaattaga
    36841 agaaattctt aaaaacgaaa attaaaagct tccaacatct gacaaaatag tcggatgttt
    36901 ttttgatttt ttacgaactt ttacgaatag atagatgagt agaaaaagaa atggagttat
    36961 ttatgaaaat cacaaactat gaaatctata agttaaaaaa atcaggtttg accaatcaac
    37021 agattttgaa agttctagaa tacggtgaaa atgttgatca ggagcttttg ttgggtgata
    37081 ttgcagatat atcaggttgc cgtaatccag ccgtttttat ggaacgttat tttcagatag
    37141 acgatgcgca tttgtcgaaa gagtttcaaa aatttccatc tttctctatt ttagatgact
    37201 gttatccttg ggatttgagt gaaatatatg atgcgcctgt acttttattt tacaagggaa
    37261 atcttgacct cctgaaattc ccgaaggtag cggtcgtggg cagtcgtgct tgtagcaaac
    37321 agggagctaa atcagttgaa aaagtcattc aaggcttgga aaatgaactg gttattgtca
    37381 gtggtctggc caagggcatt gacacagcag ctcatatggc agctcttcag aatggcggaa
    37441 aaaccattgc agtgattgga acaggactgg atgtgtttta tcctaaagcc aataaacgct
    37501 tgcaagacta catcggcaat gaccatctgg ttctaagtga atatggacct ggcgaacaac
    37561 ctctgaaatt tcattttcct gcccgtaatc gcatcattgc tggactttgt cgtggtgtga
    37621 ttgtagcaga ggctaagatg cgttcaggta gtctcattac gtgtgagcga gcaatggaag
    37681 aaggacgcga tgtctttgct attcctggta gcattttaga tggactatca gacggttgcc
    37741 atcatttgat tcaagaagga gcaaaattgg tcaccagtgg gcaagatgtt cttgcggaat
    37801 ttgaatttta aaaatgacct aagctaaaat tctaagaaaa aatcaatttt aagagaaaat
    37861 gaacccaaca tttccataat aaaacgcata ttagcaagtt tttaacactt gataatatgc
    37921 gttttttcta agtggattag tagagtagag gatttttctc atataatact cttcgaaaat
    37981 ctcttcaaac tacgtcagct tccatctgca acctcaaaac agtattttga gctgacttcg
    38041 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgtggctag cttcctagtt
    38101 tgcgctttga ttttcattga gtataaggga aagtatagtg aattgaaata agatgtgaac
    38161 aactctatca ggaaagtcaa attaatttat agaaatattt tagcagccaa ggtgcactgt
    38221 tatagattca atacactata atttagtgta attgagaaag gagaaatgat tgtgattgat
    38281 gttggctagg ttatgttcaa tgattcctac cgtctcaaat cttgtcagta aggaaaaata
    38341 aattcttcaa aagtagagat tacaaggttt gtttaagaaa gaattcaaag accttgacaa
    38401 ataaaaataa aatggttatt ataagaaatg gtctaaaata gatgatgata cttttcgaaa
    38461 atctttttac gtcagctcag ctttgccttg ctgtgttttg agcaagctac ggttagcttc
    38521 cgagtttgat tttcatttac tagaaatgaa actgatgaga gatatcagta gacatttgag
    38581 tcaggatatt atggaaaatg ataaaaagag ctcgtgagat tggcatatca gactactaaa
    38641 gtattgagtt tgttaggatt ttagcgacta gttagctggg aaaggaagat atttgtgaca
    38701 aataataaac tgtattcgtt gatagaattt agaaataaaa tatatgaaga attagaactt
    38761 tccagaagtg atttagcgat tttactatgt gccatgctta tcgcctctat cggattaaat
    38821 atggattcga ctcccgtgat tattggagcc atgttaatct ctcctttgat gacacctatt
    38881 ctgggagtgg ggctctctct agctatattt gattttaaat tgttaagaaa atcttttaaa
    38941 atattagcta ttcaaattct tgccagtcta atagcttcaa cactttattt ttatctttct
    39001 cccatttcgt atgctagttc ggagattgtt gctagaacct ctccgactat ttgggatgtt
    39061 ctcattgctt ttgtaggagg gatagcaggt attattggtg ctaggaaaaa agagaccaat
    39121 aatattgttc ctggtgttgc tattgcaacc gccttgatgc ctcctctttg tacagtaggt
    39181 tatgctattg cttctgctaa tctaaaattt atcataggct cctcttacct attcctcatc
    39241 aattgtagct ttattgtcat tgcgacttat ataggtgtta ggttgatgat ggttaagaaa
    39301 cattatttta aagataatga agaagactct aaaatgcgta ggattttgct tctagttgct
    39361 gttttgctga tgattccgag tttcatctct gcaacgactt tagtgagaga aacgttgaaa
    39421 aaagagtccc ttaagaaatt tatatcagag cagtttcagg ggcataatat tttgaaaaaa
    39481 acctattcta aaaagactca taccctaaag ctaaccatct caggaaatta tttgacagaa
    39541 gaagaactcg atatgatttc aagtaagaga ggtgactatg gtttaagtga tgtttctgtt
    39601 caagtttcac aattgtctga ttcagaacaa cttagtaagg aagagctggt ggagtatttc
    39661 ttccagtata tcaaggataa ggaagcaaaa gaaaaggaga aagctaataa atttgataca
    39721 gagtctgagg agcaataatt tcttgagaat agctggtttc tctcgtgagt cttctatgta
    39781 tatcaaagga agactgaggt tttaagtata aaacttttct tctattatag tagctaagtc
    39841 ttgacagggt tcaaaaaatg gtttacactt tataaagttt attactttga aaaggtgtga
    39901 tactgtggct acggcaacaa aaaagaaaaa atcaacagtt aaaaaaaatc tagtcatcgt
    39961 ggagtcgcct gctaaggcca agacgattga aaaatatcta ggcagaaact acaaggtttt
    40021 agccagtgtc gggcatatcc gtgatttgaa gaaatccagt atgtccgtcg atattgaaaa
    40081 taattatgaa ccgcaatata ttaatatccg aggaaaaggc cctcttatca atgacttgaa
    40141 aaaagaagct aaaaaagcta ataaagtttt tctcgcgagt gacccggacc gtgaaggaga
    40201 agcgatttct tggcatttgg cccatattct caacttggat gaaaatgatg ccaaccgtgt
    40261 ggtcttcaat gaaatcacca aggatgcagt caaaaatgct tttaaagaac ctcgtaagat
    40321 agatatggac ttggtcgatg cccaacaagc tcgtcggatc ttggatcgct tggtagggta
    40381 ttcgatttcg cctattttgt ggaagaaggt caagaagggc ttgtcagcag gtcgcgttca
    40441 gtccattgcc cttaaactca tcattgaccg tgaaaatgaa atcaatgcct tccagccaga
    40501 agaatactgg acagttgatg ctgtctttaa aaagggaacc aaacaatttc atgcttcctt
    40561 ctatggagta gatggtaaaa agatgaaact gaccagcaat gatgaagtca aggaagtctt
    40621 gtctcgtctg acgagtaaag acttttcagt agatcaggtg gataagaaag agcgcaagcg
    40681 caatgctcct ttaccctata ccacttcatc tatgcagatg gatgctgcca ataaaatcaa
    40741 tttccgtact cgaaaaacca tgatggttgc ccaacagctc tatgaaggaa ttaatatcgg
    40801 ttctggtgtt caaggtttga ttacctatat gcgtaccgat tcgactcgta tcagtcctgt
    40861 agcgcaaaat gaggcggcaa gcttcattac ggatcgtttt ggtagtaagt attctaagca
    40921 cggtagcaag gtcaaaaacg catcaggtgc tcaggatgcc catgaggcta ttcgtccgtc
    40981 aagtgtcttt aatacaccag aaagcatcgc taagtatctg gacaaggatc agctcaagct
    41041 atataccctt atctggaatc gttttgtggc tagccagatg acagcggccg tttttgatac
    41101 catggctgtt aaattgtctc aaaaaggggt tcaatttgct gccaatggta gtcaggttaa
    41161 gtttgatggt tatcttgcca tttataatga ttctgacaag aataaaatgc taccagatat
    41221 ggctgttgga gatgtggtca aacaggttaa tagcaaacca gagcaacatt tcacccaacc
    41281 gcctgcccgt tattctgaag caacactgat taaaacctta gaggaaaatg gggttggacg
    41341 tccatcaacc tatgcgccaa ccattgaaac cattcagaaa cgttattatg ttcgcctggc
    41401 agccaaacgt tttgaaccga cagagttggg agaaattgtc aataagctca tcgttgaata
    41461 tttcccagat atcgtaaacg tgaccttcac agctgaaatg gaaggtaaac tggatgatgt
    41521 cgaagttgga aaagagcagt ggcgacgggt cattgatgcc ttttacaaac cattctctaa
    41581 agaagttgcc aaggctgaag aagaaatgga aaaaatccag attaaggatg aaccagctgg
    41641 atttgactgt gaagtgtgtg gcagtccaat ggtcattaaa cttggtcgtt ttggtaaatt
    41701 ctacgcttgt agcaatttcc cagattgccg tcatacccaa gcaatcgtga aagagattgg
    41761 tgttgagtgt ccaagctgtc atcagggaca aattattgag cgaaaaacca agcgtaatcg
    41821 ccttttctat ggttgcaatc gctatccaga atgtgaattt acctcttggg acaagcctgt
    41881 tggtcgtgac tgtccaaaat gtggcaactt cctcatggag aaaaaagtcc gtggtggtgg
    41941 caagcaggtt gtttgtagca aaggcgacta cgaggaagaa aagattaaat aagaggaggg
    42001 gcccgaaagt aaatttcagg ctccttttgg ttagaacttg acaaaataca tcattttatg
    42061 cgaaactaga agaagattat tttaactagg agaagttatg cgtcttatct atctgataat
    42121 tggtttttta tcactggcct tggctattgt tggggttgtt ttacccttgt tgccgacaac
    42181 gcctttcctt ttgttgtcta ttgcttgttt ctccagaagt tccaagcgtt tcgaagactg
    42241 gctttatcat accaagctct atcaaacata tgtagctgat tttcgcgaga ctaagtctat
    42301 tacgcgtgaa cgaaagaaaa aaatcatcgt ctctatctac gtcttgatgg gaatttctat
    42361 ttattttgca cctcttttac cagtcaaaat cggtctgggt gctttgacca tctttatcac
    42421 ttattatctt ttcaaggtca ttccagacaa agaatagtta aaacagtagt tatttgcctt
    42481 gataaaattg aaagcatatt cataataata tgatataata aatttgaagt aatattcaag
    42541 gagaatcaaa tgatttacga attttgtgct gaaaatgtga ctttacttga aaaagcgatg
    42601 caggctggag ctcgtcggat tgaactctgt gataatctag cagttggtgg gacaacaccc
    42661 agctatggag tgactaaggc agcggttgaa ctggcagcta actacgatac aaccatcatg
    42721 accatgattc ggccacgtgg tggtgacttt gtctataatg acctagaaat tgctatcatg
    42781 ctagaagaca ttcgtttgac tgctcaggct ggaagtcaag gggttgtatt tggaacttta
    42841 actgctgata aaaagttgga taagcctaat ctggaaaagt taattgctgc atcaaaagga
    42901 atggaaattg tctttcacat ggcctttgat gaactaagtg atgaagatca accggaagct
    42961 attgactggc tcagtcaagc cggtgtcact cgtatcctaa ctcgtgctgg tgtgtctggc
    43021 gactccttag aaaaacgttt tgttcactat cacagaattt tggagtacgc taaaggtaaa
    43081 attgaaattc taccaggtgg ggggattgac cttgaaaacc gtcaaacctt tatcgaccag
    43141 gtgggggtaa cacaattgca tggtactaag gttgtttttt aaaaaataga aaggaactgc
    43201 tagctttggg tagcagtttt cacttatgtt tgaaattttt aaatcctatc aatttaatca
    43261 agaaaaggct catgattatg gttttataga aaatagcgaa gtctggacat atagttgcca
    43321 gattttgcaa ggtgactttg tcatgactgt gtccatcact gctgataatg tgaactttca
    43381 agtctttgac caagagactg gtgacctcta tcctcacgtt catatggaaa gcatgagggg
    43441 aagttttgtc ggaaatgtcc gtgaggcttg tctggagatt ctttaccaga ttcggaaggc
    43501 ttgttttgat gtgcaagatt ttatctgtca tcagactaag cgtatcatga ctcaagttca
    43561 ggaaaagtat ggaaaccagt tggagtatct gtgggaaaaa tcgcctgata cagctgtatt
    43621 gcgccatgaa ggcaatcaaa agtggtatgc cgtcttgatg aaaatctctt ggaataagct
    43681 ggaaaagggc agagaaggac aagtggaagc agtcaacctc aagcatgacc aagtagctaa
    43741 tttgctttca caaaagggga tttatccagc cttccatatg agcaagcgct actggattag
    43801 tgtgtccctt gatgatactt tatcagatga agaagtactg gaattgatag aaaaaagttg
    43861 gaacttaacc tctaaaaaat gaaatatttt aataattttc atgaactttc aattagctga
    43921 atattcttta ctgaagaaat tttcagaaaa tataggattt accacaccag aggaatgtgg
    43981 tgccatcttc aaatacctga ttgagaatgt caagacggat cgtcagatca tctattcgcc
    44041 tcactgtcat gatgacctcg gaatggcagt ggcaaatagc cttgctgctg tcaagaatgg
    44101 tgcaggacgt gttgaaggga ctatcaatgg tattagggag cgagctgaaa atgctgcttt
    44161 ggaagaaatt gcagtggctc tcaatattcg ccaagattac taccaagtag aaaccagtat
    44221 tgtcctaaat gagaccatca atacgtcaga aatggtttct cgcttctctg gtattccagt
    44281 tcctaaaaac aaagccgtcg ttggtggcaa taccttctcc cacgaatctg gtattcacca
    44341 agatggagtc cttaaaaatc ctctcactta tgagatcatc acacctgaat tggttggtgt
    44401 taagattccg cttggaaaat tatctggtcg ccatgctttt gttgagaaac tgagagaatt
    44461 ggccctagat tttacagaag aggatatcaa accactcttt gctaagttca aggcactggc
    44521 cgataagaag taagaaatca cagatgcaga tactcgagct ttggtagctg gaaccatggt
    44581 tgaaaatcca gaaggcttcc actttgatga tttacaactt caaactcatg cagataatga
    44641 cattgaagcg ctcgttagcc tagccaatat ggatggtgag aaagtcgaat ttaatgcgac
    44701 agggcaaggt tccgttgaag caatctttaa tgctatcgat aagttcttta accaatctgt
    44761 tcgtttggtg tcctacacta tcgatgcggt aacagatgga atcgataccc aggatcgggt
    44821 tttggtcact gttgaaaaca gagatacaga aaccatcttt aatgcagcag ggcttgattt
    44881 tgatgtgttg aaggcttctg ctattgtcta tataaacgct aatacctttg ttcaaaaaga
    44941 gaatgcaggt gagatgggac gcagtgtttc ttaccacgat atgcctagtg tgtaaaggag
    45001 aaggctatgg caaagaaaat agtagctcta gcaggagacg gaattggccc agaaatcatg
    45061 gaggttggtt tagaagttct ggaggctcta gctgaaaaaa caggttttga ctatgagatt
    45121 gacagacgac cgttcggagg tgcagatatt gatgcagcag gacctccctt acctgatgaa
    45181 acccttaagg caagtaggga agcagatgct atcctactag cagctatcgg tagtcctcag
    45241 tatgatggag cagtggttcg ccctgaacag ggcctgatgg ctctccgtaa ggaactcaat
    45301 ctttacgcta atattcgtcc tgtaaaaatc tttgacagtc tcaagtattt gtcaccactc
    45361 aaactggaac gaattgctgg tgtagacttt gtcgtggtgc gtgaattgac aggcgggatt
    45421 tactttggag atcatattct tgaagagcgc aatgcgcgtg atatcaacga ctatagctat
    45481 gaggaagtgg agcggattat tcgcaaagcc tttgaaattg caagaaatcg cagaaaaatc
    45541 cttactagta tcgataagca aaatgttcta gcgacctcaa aactctggcg gaaagtagct
    45601 gaggaagtcg cacaggattt cccagatgta accttggaac accagctggt agactcagct
    45661 gctatgctta tgattaccaa tcctgctaag tttgatgtta ttgtaacgga gaatcttttt
    45721 ggagatattt tatctgatga atcaagcgtc ttatctggta cacttgaggt tatgccatca
    45781 gccagtcatt ctgaaaatgg accaagtctc tatgaaccta ttcacggttc agcacctgat
    45841 attgcaggtc aaggaattgc caatcctact tccatgattt tatcagttgc catgatgttg
    45901 agagatagtt tcggacgtta tgaggatgca gagcgtatca aacgtgctgt tgagacaagt
    45961 ctggcggcag gaattttaac gagagatata ggaggtcagg cttcaacaaa ggaaatgacg
    46021 gaagctatta ttgcaaggtt atgaagttag acgaaaaaat tactctagtc cttttgattt
    46081 ggaatgtcat cattttcttg atttatggca ttgacaaatt caaggcaaga agaagagctt
    46141 ggcgcatccc agagaaaatc ttactcattt tagcccttac ttgtggtggt tttggggcct
    46201 ggttagctgg aattactttt caccacaaga ctcgaaaatg gtactttaaa acagtttggt
    46261 ttcttgggat ggtgaccaca ctagtagcct tatattttat ttggaggtaa tggatggcag
    46321 ggtcttcgag ggaacacgct gcttgggctc tagcggacta tggttttaag gtcgtgattg
    46381 caggatcttt cggtgacatt cattacaata atgaactcaa taatggcctg ttgccaatcg
    46441 ttcagcctag agaggttaga gagaaattag cccagctaaa accaaccgac caggtaactg
    46501 tggacttgga acaacaaaaa atcatctcac cagttgaaga attcaccttc gagatagata
    46561 gcgagtggaa acataaactc ctaaatagtt tggatgatat cggtattacc ttgcagtatg
    46621 aagagttgat tgttgcttat gaaaaacaac gaccagccta ctggcaggat tagaaaaaat
    46681 agaaaaggaa atatagtaaa ctgaaataag atgtaaacaa atgaattaga gcttaacatc
    46741 catttccagc aattttttag aaactacagt ggactattct ggattcaaca cattataaaa
    46801 ttatgacaaa acacattcac aagaaggcta cgacatttta aaaggtgagg gcggatgtat
    46861 cgtttgccct actaaagttg gttacattat catgaccagc aacaaggcag gacttgagcg
    46921 taagttcgca gccaaagaac gtaagcgtaa caaaccaggt gttgttctct gcggtagcat
    46981 ggatgaactt tgcgctttag cgcaactcaa cccagaaatt gaagcattct actaaaaaca
    47041 ttgggatgaa gatattcttc ttggttgtat ccttccttgg aaaccagaag tctttgaaaa
    47101 actcaaagca tacggggatg gccgtgaaga acttatgact gatgtacgtg gtactagctg
    47161 ttttgttatc aagtttggaa aagcaggtga acaattggct gccaagcttt gggaagaagg
    47221 taaaatggtc tacgcctcat ctacttcaat gacaaaacga ttgaaactcg ctatgagagc
    47281 aaggtgtaat ggtgtctatg gtcgataagg acggcaaact catcccagaa caaggaggag
    47341 cacgttcaac ctcaccagca ccagttgtga tccgtaaagg gcttgacatt gataaaatca
    47401 tgatgcacct gtcagatact tttaactcat gggactaccg tcaggttgag tattattagg
    47461 atagagaaga agtctagtgt taaggacatt acagctcata atactaggct tttttataga
    47521 aattcttttc tttttctata ggatatggta ttctatgtag aaaatatatg ttaataagta
    47581 atgccaatat ttaaacatca ttagtaaaag gagttagatt gatgaataaa agaaaagtta
    47641 gtttagaaga tttttataaa tggtatagtc taaataaaga agagttatta aataaggcaa
    47701 ctgttggtga aaagtttaat gataaattaa aagaagagtt tctccaggaa tggcctttgg
    47761 ataggatttt aacaatgtca atcgatgaat atgtaatagg aaagggacag caaaataagt
    47821 ctttatgcta cgctcttgag aagggaaaat acaaaaatct atttcttgga atttctggtg
    47881 gctcagcttc aaaatttggt atttattgga ataaaaaaac aaacaaatat aaagatcaag
    47941 ctaataatga gatttcagag ttggatcagc gattttcaaa attaaaatca gatttgtatg
    48001 aaattatcaa agaaggtatt cgttttaact ttgaaaatcc tatttttgat atgaaaagat
    48061 caacaaatga atttattggt cgttctgcta tggtgacaaa attactttgt atctattctg
    48121 ggggagatcc tttctttggt gtaaatatta atagtcagaa agaattttgg aaccactttg
    48181 tttctcagac aaatcaaggt ggaccttatc tgcaaaatca taaaataatt gaactggtgt
    48241 ccaaaactta tcctgagttg gagccatcga aattaggaac tatgcttttt gagtattcta
    48301 agctttttat ggaaaataag gaagacaata gtacaatgga ttcatcaaac aattttcgtc
    48361 atcaattaac tcaatctcta ttaaagtctc caaaccttat ccttcgtggt gctcctggca
    48421 caggaaagac ttatcttgct aaagaaattg ccaaagaatt aacggatggc aacgaagacc
    48481 aaatcggatt tgtacaattt cacccatcct atgattatac ggattttgta gaaggtttaa
    48541 gaccagtatc aaatggggat ggagctattg agtttaggct acaggacggt atttttaaag
    48601 atttttgtca gaaagcaaaa gaaacccaat tgattggagg acaagataat tttgatgagg
    48661 cttgggattc ttacttagaa tatataaatg ttgctgaaga aaaagaatat ataacaaaaa
    48721 catcttactt atctgttaat agtagacaaa atttgtcagt aaattatgat agtggtgttc
    48781 caggatggtc actacctagc aaatatgttt acgagttgta taaagataaa aattataata
    48841 agcaagaata ctacaaaagt ggtggaaaaa ctgtcctaga aacattgaga aagagatttg
    48901 gtttgaaaga ctatgtttcc ccaacagaaa ttgatactga taagaaattc gtcttcatca
    48961 tcgatgaaat caatcgtggg gagatttcta agatttttgg cgaactcttt ttctctatcg
    49021 accctggcta tcgtggtgaa aaaggaagtg tttctaccca atatgcaaat ctacacgaaa
    49081 ctgatgaaaa gttctatatc cccgaaaatg tttacatcat cggaactatg aatgatattg
    49141 atcgttcagt ggataccttt gattttgcta tgcgtcgtcg ttttcgtttt gttgaagtta
    49201 ctgccgaggg tcaagttggc atgttggata aagagctgaa tatccatgca gaagaagcaa
    49261 aaattcgtct aagaaacttg aacgctgcta tcgaaaatgt tcaggaatta aacagtcatt
    49321 atcatattgg accaagttat tttcttaagt tgaaggatgt agattttgac tatgaattac
    49381 tctggtccga ttatattaag cctctcctag aagactactt gcgaggttct tatgatgagg
    49441 ttgaaacttt ggaaactttg aaaaaagcat ttgaactgac aaataatgat caaactggtc
    49501 aacaagatac tggtgataat gatgcggatt actgataatc aatacaagat tattaaagaa
    49561 aaatttgttg aagaatatcc gaaactaagc aatcttcttt tagacagaac cttggaaagt
    49621 ctatcccaag atgaacgtat tttcattttt ccaaatgatt tgactcatac tcctgatttg
    49681 gataaggacc aaaagatttt tgaaacagtc aatcagaaaa tcaagacagg gaacgtgatt
    49741 ggttttcttg gatatggtca ggaaagatta acgatttcct cacgattttc tgatgagagt
    49801 aatgaccatt ttttgcatta tctcttaaac aaggttcttc atatcaatct cactagttta
    49861 gatgttgctt tgtctcgtga agagaggctt tatcaacttt tgatgtatct cttccccaag
    49921 tatctacaag ctgctattcg aaaaggtctt tataaggaat accagagatt ttctcataac
    49981 gacagtcatg ttaagggagt gattgatgta agaaaccatc tcaagaaaaa tcttcctttc
    50041 acgggaaata ttgcctacac aacgagagag ttcacctatg ataatcccct catgcagttg
    50101 gtccgtcaca ctattgaata cattaagaat cagaaaagca ttggtcaagg ggtactagat
    50161 aatctctcaa ctagtcgtga aaacgtatct gaaatcgtgc gtgtaacgcc ctcttataaa
    50221 ctagctgatc gtgctaagat tattcgggga aatcaatcta aacctatacg tcatgcatac
    50281 tttcacgagt acagaaactt acaagaactt tgtctgatga tcctaaacca agaaaagcac
    50341 ggtttagggt atcaagatca aaaaatctat ggtattctct ttgatgttgc ctggctttgg
    50401 gaagagtatg tttacacctt gttgccaaaa ggttttgtac atcccagaaa taaggataag
    50461 acggatggaa tttcagtatt ttctgttggg aaacgaaaag tatatccaga tttttatgac
    50521 agagaacgaa agattgttct agatgcaaaa tataaaaaac tggaattgac tgaaaaagga
    50581 atcaaccgtg aggacttatt ccagctgatt tcctattctt atattttaaa agctgagaag
    50641 gctggactga tttttcctag tatggagcag tcagtaaata gtgaaatagg aaaagtagct
    50701 ggctatggag ctcaattgaa gaagtggtct attcgaatcc ctcagaatgc ctcattctat
    50761 agtacatttt gtaaaatgat ggaaaattca gaagaaaatt ttaaagcgat tattgatgaa
    50821 gaagtgggga gaaaataatt tcccctcttt cttttatttt taacacaagt aaaacccgaa
    50881 cgatatattt taattcataa aataatttga caaaaactgt actttggttt ataataaatt
    50941 aaggaaacgt cggaaaaggc gtagtgatgc aagagcatag gtaggtcatt acaaaagaaa
    51001 cgagacatcg atatgttaaa tgaatttcca atttttgatt acgaagatat tcaattgatt
    51061 ccaaataaat gtgtcattaa aagccgtgca gaagcggata caagtgtcac tttaggaaat
    51121 cacaccttta aactacctgt tgtgccagcg aatatgcaga cgattttgga tgaaaatgta
    51181 gcagagcaac tggctaaagg tggttacttc tacattatgc accgttttga tgaggcagga
    51241 cgcattcctt ttattaaacg aatgcacgat caagggctca ttgcttctat ctctgtcggt
    51301 gttaaggatt atgagtatga tttcgttaga cagctcaaag ctgatgctcc tgagtatatc
    51361 actattgata ttgctcatgg tcatgcggat agcgtgattt ctatgattca acacatcaag
    51421 aaagaattgc cagatacctt tgtcattgct ggaaatgtgg gaacaccaga agctgtgcgt
    51481 gaattggaaa atgctggtgc ggatgctact aaggtcggaa tcggtcctgg taaggtttgt
    51541 atcaccaagg ttaagactgg ttttggtaca ggtggttggc agttggctgc tctacgctgg
    51601 tgtgccaagg ctgcgcgtaa accgattatc gctgatggag gaattcgtac tcacggtgat
    51661 attgctaagt ctatccgctt cggtgctagc atgatcatga ttggttccct ctttgcagga
    51721 cacattgaaa gtccagggaa aacgattgaa gtcgatggtg aacagttcaa agaatattat
    51781 ggttcagcct cacaatatca aaaaggtgct tacaaaaatg tggaaggcaa acgtatcttg
    51841 cttcctgcta aaggtcatct gcaagacact ttaactgaga tggaacaaga ccttcaaagt
    51901 gctatttctt atgcaggtgg acgtcaggtt gctgacctta aacacgttga ttatgtgatc
    51961 gtgaaaaact ccatctggaa tggggatgct tcccactaag acggggtctt tgaccaaaaa
    52021 acttgttatt agagcaaatt tctgttataa taaaacaagt ttccaccctt agtgtaatgg
    52081 atatcacgta agattccggt tcttgagatg ggggttcgat tccctcaggg tggatgtaaa
    52141 catcctaaaa agcctttaat agggcttttt tctttatcct gacccaaatt tgccgctaaa
    52201 actgagaatc tctgtctaaa gaattcccaa atgctttcca gtcccgtttt agagtgactc
    52261 agggggcttt ttttgatata ataaaaagga ctattatcag ttagaaagag gttggtatga
    52321 aagaattaca aactgtacta aagaatcatt ttgcaatcga atttgcagac aaaaatttac
    52381 tggaaactgc ctttactcat acgagttatg ccaatgagca ccgcctctta aaaatttcac
    52441 acaatgaacg cttggaattt ttaggagacg ctgttctaca gttattgatt tcagaatatc
    52501 tatataaaaa atatcctaaa aagcctgaag gtgacctatc aaaactccgt gctatgattg
    52561 tccgtgagga gagtttagct ggttttgcgc gtgattgcca gtttaaccag tttatcaagt
    52621 tgggtaaagg ggaagaaaaa tcaggtggtc gcaatcgtga caccattctt ggtgatgcct
    52681 ttgaagcctt tcttggtgcc cttcttttgg ataaggatgt ggccaaggtc aaggaattta
    52741 tctatcaagt catcattcct aaggttgaag caggcgagtt tgagatgatt acagactata
    52801 aaacccatct ccaagagttg cttcaggtca atggtgatgt ggctattcgt tatcaggtga
    52861 tttctgaaac agggcctgct catgataagg tctttgatgt agaagttctt gttgaaggta
    52921 agagcatcgg tcaaggccaa ggtcgttcta agaaattagc agagcaggaa gctgccaaaa
    52981 atgccgttga gaaggggctg gattcatgta tttaaaggaa atcgaaattc aggggttcaa
    53041 gtcttttgct gataagacca aggtcgtttt tgaccaaggt gtgacggcag ttgttggacc
    53101 caatggatct ggaaagtcca atattacaga aagtctgcgt tgggctttgg gggagtctag
    53161 tgtcaagagt ctccgtgggg gcaagatgcc ggatgtcatc tttgctggaa ccgaaagtcg
    53221 caaaccgctc aattatgctt ctgtagttgt gactctggat aatcatgacg gatttatcaa
    53281 ggatgcaggt caagaaatca gggtggaacg ccatatctat cgtagtggag atagcgaata
    53341 caagattgac ggcaagaaag tccgtctgcg tgatattcat gacctcttct tggatactgg
    53401 attgggacga gattccttct ctattatttc ccaagggaag gttgaggaga tttttaattc
    53461 caagcctgag gaacgacgag ctatttttga agaagctgct ggagttttaa aatacaagac
    53521 tcgcagaaaa gaaaccgaga gtaaactgca gcaaactcag gataatctgg accgcttaga
    53581 ggacattatc tacgagttgg ataatcaaat caagcctctt gagaagcaag ctgagaatgc
    53641 ccgtaagttt ttagacttgg aaggacaacg taaggctatt tatttagacg ttctggttgc
    53701 tcaaatcaag gaaaataagg ctgaactaga gtcgacagaa gaagagttga ctcaggttca
    53761 agaactcttg atgagttatt accaaaagcg tgaaaaatta gaagaagaaa atcaaactct
    53821 taaaaagcaa cgccaagatt tacaggctga aatggccaaa gaccaaggca gtttgatgga
    53881 cttgactagt ctgattagtg atttagaaag aaaattagcc ctatcgaaac tggagtccga
    53941 gcaagtggcc ttgaatcaac aggaggcaca agcccgtttg gctgctttgg aggataagag
    54001 aaattcactc agcaaagaaa agtctgataa agaaagctct ttagctctgt tagagggaaa
    54061 tctagtccaa aataatcaaa aactcaatcg tttagaagct gaattgctgg ctttttcaga
    54121 tgatcctgat cagatgattg agcttttgcg tgaacgcttt gtggcgcttt tacaagaaga
    54181 agcggatgtc tcaaaccaac tgacccgcat cgagaatgag ttggaaaata gtcgtcagct
    54241 ttctcaaaaa caagcagatc aactagaaaa gctgaaagag caattggcta tagctaaaga
    54301 gaaggctagt cagcaaaagg aagagcttga aactgccaag gagcaggttc agaaattatt
    54361 ggctgactat caagctattg ccaaggagca agaggagcaa aaaacttcct atcaagctca
    54421 acaaagtcaa ctctttgacc gtctggatag tcttaaaaac aagcaggcta gagctcaaag
    54481 tttggaaaac atccttagaa atcacagtaa cttttatgca ggtgtaaaga gtgttctcca
    54541 agaaaaagac cgccttggtg ggattattgg tgctgttagt gagcatttga cctttgatgt
    54601 gcattatcaa actgccttag agattgcact tggagccagc agtcagcata tcatcgtaga
    54661 agatgaagag tcggcaacca aagctattga tttccttaaa cgaaacagag ccggtcgtgc
    54721 aaccttcctt ccgttgacaa caatcaaggc tcgtacgatt tctagccaga atcaagatgt
    54781 tatcgctgta agcccaggtt tccttgggat ggcagatgag ttggtgactt ttgatactag
    54841 actggaagcc attttcaaga atttgctaga tacgacggct atttttgata ctgtagagca
    54901 tgcgcgtgca gcagctcgcc aagttcgtta tcaggttcgt atggtgacat tggatgggac
    54961 agaattacgc acgggtggtt cctatgcggg tggtgccaat cgccaaaata acagtatttt
    55021 catcaagcca gaactggagc aattacaaaa agaaattgct gcagatgaag caagcttggg
    55081 ttcagaagaa gcggctttga agaccttgca agaccagatg gctacattga cagaaagatt
    55141 agaagccatc aaatctcaag gagaacaggc acgtattcag gagcaaggct tgtccctcgc
    55201 ttatcagcaa actagtcagc aagttgaaga actggaaact ctttggaaac tccaagaaga
    55261 ggaaaaagat cgtctttctg atggagattg gcaagcagac aaggaaaact gccaagagcg
    55321 tcttgctgca atcgccagtg acaagcaaaa tctggaagct gagattgaag agattaagtc
    55381 taataaaaat gccatccaag aacgctatca aaacttgcag gaagagctag cgcaagctcg
    55441 tttgcttaag acagaactgc aagggcaaaa acgttatgaa gtggctgata ttgaacgctt
    55501 aggcaaggaa ttggacaatc ttgattttga acaagaggaa atccagcgcc ttcttcaaga
    55561 aaaggttgac aatcttgaga aggttgatac agaattgctc agtcaacagg cggaagaatc
    55621 caaaactcag aaaacgaact tccaacaagg tttgattcgc aaacagtttg agttggatga
    55681 tatagaaggt cagctggatg atattgctag tcatttggat caggctcgcc agcagaatga
    55741 ggagtggatt cgcaagcaaa cacgtgctga agccaagaaa gaaaaggtca gcgagcgctt
    55801 gcgccatcta caaagtcaat taacagacca gtaccagatt agctatactg aagctctaga
    55861 aaaagcgcat gaattggaaa acctcaatct ggcagagcaa gaagttaagg atttagagaa
    55921 ggctattcgc tcactgggtc ctgtcaatat agaagctatt gaccagtacg aagaagttca
    55981 cagccgtctg gatttcctca atagccagcg agatgacatt ttgtcagcga aaaatctgct
    56041 tcttgagact attacagaga tgaatgatga ggtcaaggaa cgctttaaat caacctttga
    56101 agctatccgt gagtccttta aagtgacctt caagcagatg tttggcggag gtcaagcgga
    56161 cctgattttg actgagggag acttgctgac agctggggtt gagatttctg ttcaacctca
    56221 aggtaagaaa atccagtccc ttaatctcat gagtggtggt gaaaaagctc tatcggctct
    56281 tgccttgctc ttctccatta ttcgtgtcaa gactattcca tttgttatct tggatgaggt
    56341 ggaagctgcg ctggatgaag ccaatgttaa acgttttggg gattacctca accgctttga
    56401 caaggacagc cagtttatcg tcgtaaccca ccgtaaggga accatggcag cggctgattc
    56461 catctatgga gtgaccatgc aagaatcggg tgtttcaaag attgtttcag ttaagttaaa
    56521 agatttagaa agtattgaag gatgacaatt aaactagtag caacggatat ggacggaacc
    56581 ttcctagatg ggaatggacg ctttgatatg gatcgtctca agtctctctt ggcttcctac
    56641 aaggaaaaag ggatttactt tgcggtggct tcgggtcggg gatttctgtc tctggaaaaa
    56701 ttatttgctg atgttcgtga tgacattatt ttcatcgcgg aaaatggcag tttggtagag
    56761 tatcaaggtc aggacttgta tgaagcgact atgtctcgtg acttttatct ggcaactttt
    56821 gaaaagctga aaacgtcacc ttatgtagat atcaataaac tgctcttgac gggtaagaag
    56881 gggtcatatg ttctagatac ggttgatgag acctatttga aagtgagtca gcattataat
    56941 gaaaatatcc aaaaagtagc gagtttggaa gatatcacag atgacatttt caaatttaca
    57001 accaacttca cagaagaaac gttagaagct ggtgaagctt gggtcaatga taatgtccct
    57061 ggtgtcaagg ctatgacaac tggctttgaa tctattgata ttgttctgga ctatgtcgat
    57121 aagggtgtag ctattgttga attagctaaa aaacttggta tcacaatgga tcaggtcatg
    57181 gcttttggag acaatcttaa tgacttacat atgatgcagg ttgtgggaca tcctgtagct
    57241 cctgaaaatg cacgacctga aattttagaa ttagcaaaga ctgtgattgg tcaccataag
    57301 gaacggtcgg ttatagctta tatggagggc ttataatggc agatataaaa ttgattgcat
    57361 tggacttgga cgggaccttg ctgactactg ataaaaggct gacggatcgt accaagtcaa
    57421 ccttgaaagc tgcgcgtgat cgtggtatca aggtcgtatt gacaactggt cgtcccttaa
    57481 aagccatgga tttctttctc catgagttag ggactgacgg tcaggaagat gagtatacca
    57541 ttacttttaa tggtggatta gttcagaaaa atacaggaga aatccttgat aaaacagtct
    57601 tttcatatga tgatgtggca cgtttgtatg aagaaacaga gaaattatca ctgcctcttg
    57661 atgccatctc agaaggaaca gtttatcaaa tccaatcgga ccaagaaagt ctttatgcca
    57721 aattcaatcc agctttgact tttgttccag ttgactttga agacctgtct agtcaaatga
    57781 cctacaacaa atgcgtgacc gcctttgctc aagaaccctt ggatgcagcc attcagaaga
    57841 tttctctaga attgtttgac caatatgaaa tctttaaatc acgtgaaatg ttgctagaat
    57901 ggtcaccaaa gaatgttcat aaagcaacag gtttggcaaa actaatcagc catcttggaa
    57961 tcgaccaaag ccaagtgatg gcttgtggtg acgaggccaa cgacctctct atgattgaat
    58021 gggcaggtct tggtgttgct atgcaaaacg ctgttcctga agtaaaggta gccgcaaatg
    58081 tagtgacgcc gatgaccaac gatgaggaag ctgtcgcctg ggctatcgaa gaatatgtgc
    58141 taaaggagaa ctaagatatg ggattgtttg accgtttatt cggaaaaaaa gaagaaccta
    58201 aaatcgaaga agttgtaaaa gaagctctgg aaaatcttga tttgtctgaa gatgttgatc
    58261 ttaccttcac agaagctgat gaagttcctc aggaagaagc agaggttgaa attgttgaac
    58321 aagctgtgtt ccaagaagag gaaatccaag acacagttga agaaagtcag gattcagagc
    58381 cagctgtagg ggtttctcaa gaagaaatag aagaattacc aaactcagaa gaattaccag
    58441 aggaagagaa gcttgagcac gaaggaactg tagaagaaaa taattctgaa gtgcttgaac
    58501 cagaagctcc tcaaacagaa gaaactgttc aggaaaaata tgaccgcagt cttaagaaaa
    58561 ctcgcacagg tttcggtgcc cgcttgaatg ccttctttgc taacttccgc tctgttgacg
    58621 aagaattttt cgaggaactg gaagaactgc tgattatgag tgatgttggt gtccaagtcg
    58681 cttctaactt aacggaggaa ctacgttacg aagccaagct tgaaaatgcc aagaaacctg
    58741 atgtacttcg tcgtgtcatc attgagaaat tggttgagct ttatgaaaag gatggtagct
    58801 acgatgaaag catccacttc caagataact tgacagttat gctctttgtt ggtgtgaatg
    58861 gtgttgggaa aacaacttct atcggaaaac tagcccaccg ctacaaacaa gctggtaaga
    58921 aggtcatgct ggttgcagca gataccttcc gtgcgggtgc agtagctcag ctagctgaat
    58981 ggggccgacg agtagatgtt ccagtagtaa ctggacctga aaaagctgat ccagccagcg
    59041 tggtctttga tggtatggaa cgtgccgtgg ctgaaggtat cgatattctc atgattgata
    59101 ctgctggtcg tctgcaaaat aaggataacc ttatggctga gttggaaaag attggtcgta
    59161 ttatcaaacg tgttgtgcca gaagcaccac atgaaacctt cttggcactt gatgcatcaa
    59221 caggtcaaaa tgccctagta caggccaaag aattttcgaa aatcacacct ttaacgggaa
    59281 ttgttttgac taagattgat ggaactgctc gaggaggtgt ggttctagcc attcgtgaag
    59341 aactcaatat tcctgtaaaa ttgattggtt ttggtgaaaa aatcgatgat attggagagt
    59401 ttaactcaga aaactttatg aaaggtctct tggaaggctt aatctaatca gaagcaaaaa
    59461 tcctgcaagg tacaaacttg caggattttt ttattcgaaa cgaccatctt gacgataggc
    59521 gatatctggt tgccaagtcc atttggcacc gaatttttca agtaggtcaa agctggcttg
    59581 aggtcccatg cttccagctt tatagtcatg aagtggggca ccattttcag cccagagctt
    59641 ttcaatacgg tcaatcaact tccatgacgc acaaacttca tcccagtggc taaagttagt
    59701 tgagttgtta tttaggacat cataaatcaa tttttcgtat ggttctggag aagcaccagt
    59761 tgcagtcgca tctgtacggt aatcaagtga gttaggagcc aagttaaatt cttctcctac
    59821 ttgcttccca tttaggctaa gagagaagcc ttctgttggt tgaatataga tggtcaaaat
    59881 atttggagca agtggttctc caaagataga atccatttgt ttaaagacga tgttgacatg
    59941 agttcctttt tcagtcagtc gtttacctgt acggaaaaag aaaggaacac cacggaatcg
    60001 atcgctgtct acaaagaagg caccagatgt aaaggtttca gttgttgatt ctggattcac
    60061 atttggctcg ctacgataag agatgtattt catgccatca atcttaccag agcggtattg
    60121 cccacggata aagtgttctt tgagttcttc atcagttgga tgatagaggt ttttaaagac
    60181 cttaatcttt tcagcacgaa tctcgtcttt tgtgaagctt gctggtttgt ccatggcgag
    60241 gagcgaaaga agttgtagag tgtggttttg gaccatgtca cggagggcac cggattggtc
    60301 atagtagcca ccacgttctt ctacacccaa gcgctccgca aaggtaattt gaacattgtc
    60361 gataaaatcc ttgttccaaa cgttttcaaa aatcaagttt gcaaagcgaa ctgcaaagat
    60421 gctttggatc atttccttac caagataatg gtcgatacgg aaaatttgtt cttcgtcaaa
    60481 tgttgctagg agttcgacat tcaacttgct tgcagttgcg taatctgtac caaatggttt
    60541 ttcaacgatc aagcgctcaa aacctttgcc atcgacaatg ttttcagatt tgaggtgttt
    60601 ggcaatggtt ccaaagaact gaggtgccat agacaagaag aagagcttat tgtgttcagc
    60661 ttggtatttt tcattaagct cagcttgtaa ttgacgcaaa gcaatataat gttccgaatc
    60721 attgacatca tggctttgat agtagaagtg gctagcaaat tcttgggctt gctcggtact
    60781 atctgccaaa tcaaggatgg actcgacaac tacagattca aaatattcct tactccaagg
    60841 tctacgggca gttccaataa cggcaaagtg cttggaaaga ttgccggatt gatatagtct
    60901 aaaaagggaa gggtagagct tgcgtttagc caggtctcca ctcgcaccga aaattgtaac
    60961 aataacctta gatgacatct agctacctaa tttctatttt tattcctagt cttgctaggt
    61021 atgaggaaac ctcatttcat aaacttaatt ctaacataat tttccgaaaa atcaaaaatt
    61081 ccaatacgag gtagaaaaac tgcaaggaaa tccttacagt ttgagtttag acgtttaaga
    61141 ccttatctaa gaactctttc agacgagggt gttgtgggtt atcaaagatt tggtcaggtg
    61201 ttccgtcttc aaggaactcg ccatctgcag taaagataac gcggttggca acctgacgag
    61261 caaatcccat ctcatgggtt acgataatca tggtcatgcc ttgctcagcc aattccttca
    61321 taacgttaag tacgtctcca accatctcag ggtcaagggc agaagttggt tcatcgaaga
    61381 gcatgatgtc tggattcatt gctaggccac gagcgatggc cacacgttgt ttttgaccac
    61441 ctgataggct atctggattg gcattagctt tatctgctag tccaaccttt tcaagcaact
    61501 ccattcccaa ttcctcagct tcttccttag tcatcaactt gtgctcaata ggagcaaagg
    61561 tgatgttgtc caatacagac atatgaggga agaggttgaa gtgttggaat accatgccga
    61621 tattttcacg gacgtggtca acattggttg ttttttcagt taaatcatag ccgttcacag
    61681 tgatgtgacc gctagtgact tcttctaaaa gattgaggct acggaggaaa gttgacttac
    61741 cagaacctga aggaccgatg atacaaacaa catctccttc atagaactta gtcgtaattc
    61801 cttttaggac ttcatttttt ccatagtact tgtgtaaatc atttacatca atttttaatt
    61861 ttgccattaa cgaatcctct tttctaagcg tttcgctagt ctagtcaaaa gtgtgataat
    61921 tacaagatag aagatagcaa ggattgcata catcttgaaa ctttggtagt tacgagcaat
    61981 gataatctta ccagtttgga agagttcaac caaaccgata gcagatacga tagttgtatc
    62041 tttaagagcg ataacgaatt ggttgacaaa gtttggcaac atcaatttag ttgcttgtgg
    62101 caagataatc ttacgcatgg tttttccata agagataccc aagcttcggc tggcttccat
    62161 ttggccaact ggaacggcct gaataccacc acgaacgatt tcagcgatat aagcagccgc
    62221 attgagtgag agggcaattg ttccagctac aaagtcgtta attgggcttt gttggcctgt
    62281 gatagactcg atgaagtttg gaattcccca gaagatgaag gctgcaagaa tcatcaatgg
    62341 aataccacga ataacgtcaa cgaaaatctc agagatgacg cgaagagatt tgtatgggct
    62401 aacgctaaac ataccgaaga taattccgat gacaatggca atagcaaatg agataagagc
    62461 tagagcaaga gtgataccaa gaccgctaag gagttgtttg tagttgtttt gaagcaagcc
    62521 ccagagcgtt gtttcgtcaa cagtacttgt tgaagcagtt gaagattcgc tagctaggta
    62581 tttgtcaaga atcttttgga attcaccgtt tgctttaagg tttgcaagtc cgttgttgaa
    62641 catttcaatc agttctggat ttgctccttt tttaacggca aaggctgttt caccgattgg
    62701 agttccagag attggagttt tcaatttttg accttggctg atagaatatt tgagaacagg
    62761 ttcatcatcc ataacggcat caatggcacc agtgtttaaa ctgtcataca ttgaagaacc
    62821 atcagcaaag gttttgattt tgtaaccgta tttgctttga ttttctgtta ggaaggtttg
    62881 agaagcagtt ccgtttttaa caccgactgt ctttcctttt agatcttcat aagaagcaat
    62941 attgcttgat tctttgacac caagaatggt attagcagtg tagtatgatt ctgagaagtc
    63001 aaaagttgcc ttacgagcat ctgtgacaga cataccagca atgataccat cggcttgacc
    63061 agcttggaca gcactgatag cagcatcaaa accagggttg gtgatttcaa tttcaaaacc
    63121 ttggtcttta gcgattgcct taatcaattc catatcaata ccagtgtatt ggttgcttga
    63181 attttggaaa acaaaaggtg caaaagaaga atcgctggca atgatatatt tagccttaac
    63241 aggaatagct tttaatcctg cgagagtagt tgtagttggc actgctgaag atgatgaagc
    63301 agtccatttc ttgataattt tatcaagact accatctttt ttcatttcag acaaggcttg
    63361 gttaaattca gtaaccaggt gctcgtattt acttcctttt ttcacaccga aagcaaaact
    63421 tcctacagct tcaccatcca tttcaatatg gaggtcttga ccttggttaa tggcatattc
    63481 gataacaggt ttgtcatcca tcatggcatc gatggcacca gcactcaagc tgttgttcat
    63541 taaatcacca gtgtcaaatg ttttaatagt aaagccgtat ttatctttga ttgtttcaag
    63601 gaaacgttga gcggcagttc cgtttttaac accaacggtt ttgccagtta attggtcgta
    63661 cttgctaatt ttgtgtgact ttgtagtagc aatgacaact tttgtatcat agtaagtatc
    63721 agacatggtg aagacttttt cacgttcttt agtctttgtc atccctgcca tgatagcgtc
    63781 ggcttgccca gcttgaaccg cattgactgc tgcgtcaaat ccaggatagg acatctgaat
    63841 gttccagcct ttaatctcag cgactttgtt aataatgtca acatcaattc ctttataagt
    63901 ttgatctgaa tctttaaact caaaaggtgc ataggcggta tcagaaacaa tcttaatcgt
    63961 ttctgctttg gcaataccta atgagaaaat tgggaataaa attagcaaaa atgctagaaa
    64021 ttttttcttc atttttagtc tccttttccg aatattctct cattatatca gaaaaagtaa
    64081 aaaaaggcaa atttttatat ttttcgtgtc agaaaatata acattgattt ttccttttct
    64141 ttcttgaatt gctattaaaa agtgctataa taatagtata tatagaagaa aagaggacgg
    64201 ggatatgaag aacaaaagaa tatttaaaga cttccaagct tcaaaaatga gtttaaacat
    64261 ttacacaagc cccttgttag cctttgtttt tgtcttcata ggagagtttg tggcttttac
    64321 tttgtatggt attggcttgt tagctctcat cggacttgct agaaattttg gagaggctgg
    64381 tcaaaatctt gcaacctact tgcagacctt gcatcagagc ttgacggata aaacaagtga
    64441 ctttcgttta attttaggat tactggcctt tggttttatt cttaacactg tgttcagatg
    64501 gacaagaaaa gttgagaaaa gacctattcg aaccttggga ttttatagag agaatttcct
    64561 cagcaatctt ctgaaaggat ttagtctagg cttggcactt tttcttctga ccttgttagg
    64621 tttagtggtc ttaggtcaat atcgtttgga atccattcac ttgaatcctt attctcttgc
    64681 ctttgtcgtc tttactatcc cattttggat tttacagggg acagcagaag aagtggtggc
    64741 ccgtgcttgg ctacttcctc aattggcctc aagaaccaat ctaaaactag ctattcttat
    64801 atctagcctg ttctttaccc tgcttcatat gggcaattct ggcctcaccc ctctatctct
    64861 agtaaatctc tttttattcg gagttgccat ggctctttat cttctcaaaa ctgatacagt
    64921 ttggggtgtt gcaggtattc atggtgcttg gaattttgct cagggtaatc tctttgggat
    64981 tttagttagt ggtcaaccgt caggaacgtc tctgatgacc tttttaccac aaggcaatca
    65041 agattggcta tcaggtggtt cttttggcat agaaggttcc attatgacaa gtctggtatt
    65101 actactgctg attgtctatc ttgctaataa attaaagaaa gaaaatgaaa ggatgtgact
    65161 tcggtccgtc cttttcttcg tgaaaatact ataagtatgc taaaatagga atagcacatg
    65221 gagagaggat tcttatgatc aatcacatta cagataatca atttaaacta gtatcaaaat
    65281 atcaaccatc aggagatcaa ccccaagcta tcgagcagtt ggtggataac attgaggggg
    65341 gagaaaaagc tcagattctg atgggggcga ctggaacagg gaagacctat actatgagtc
    65401 aggtcatttc taaagtcaat aaaccaactc tggttattgc ccacaataaa actctggctg
    65461 gtcagctcta tggggagttt aaggaatttt tccctgaaaa tgcagttgag tatttcgtat
    65521 cctactatga ttattaccag ccagaggcct atgtcccttc tagcgatacc tatattgaga
    65581 aggatagttc tgtcaatgac gagattgaca agcttcgcca ctcagctacc tcagcccttt
    65641 tggagcgtaa tgatgttatt gtcgtggcct cagtctcttg tatctatggt ttgggttcgc
    65701 ccaaggaata cgctgatagt gtcgttagtc tccgtcctgg tctagagatt tctcgtgata
    65761 aactcttgaa tgacttggtc gatattcagt ttgaacgtaa tgatattgat ttccaacgcg
    65821 gaagatttcg cgttcgtggg gatgtggtag agattttccc agcttcccga gatgaacatg
    65881 cctttcgagt agaatttttt ggagacgaaa ttgaccgtat ccgtgaggtt gaggctctga
    65941 caggtcaggt attgggagag gtggatcatt tggcgatttt cccagctact cactttgtga
    66001 ccaatgacga ccatatggaa gttgccgttg ccaagattca agcagaatta gaagagcagt
    66061 tagctgtctt tgaaaaggaa ggtaaactgc ttgaagccca gcgtttgaaa cagcggacag
    66121 agtatgatat cgaaatgttg cgtgagatgg gctataccaa tggggttgaa aattattctc
    66181 gccacatgga tggacggagc gaaggagagc ctccttatac gcttctcgac ttcttcccag
    66241 atgatttctt gattatgatt gacgagagtc atatgaccat agggcaaatc aagggcatgt
    66301 acaatggaga ccgttcgcgt aaggaaatgc tagtaaatta tggtttccgt ttaccgtctg
    66361 ccttggacaa tcgtcctctc cgtcgtgagg agtttgaaag ccatgtgcat cagattgttt
    66421 acgtatcagc gacacctggt gactatgaaa atgaacagac tgagacggtg attgagcaaa
    66481 tcattcgacc gacagggctt ttggatcctg aggtggaagt ccgtccgact atgggacaga
    66541 ttgatgatct cttaggtgaa atcaatgccc gtgttgaaaa gaatgaacga acctttatca
    66601 ccaccttgac caagaaaatg gcagaggact tgaccgacta tttcaaggaa atgggcatca
    66661 aggtcaagta catgcactcg gatatcaaga ccttggaacg gacggagatt atccgtgatc
    66721 tccgcttggg tgtctttgat gtcttggttg gaatcaatct ccttcgtgaa gggattgacg
    66781 ttcctgaggt tagcttggtt gccattctcg atgctgacaa ggaaggtttc cttcgtaacg
    66841 agcgtggact catccagacc attgggcgtg ccgcccgtaa cagtgaaggt catgtcatca
    66901 tgtatgcaga tacggttacc cagtctatgc aacgtgctat cgatgaaact gcccgccgtc
    66961 ggaaaattca gatggcctat aatgaagagc atggtatcgt accacagaca atcaagaaag
    67021 aaatccgtga cctgattgcc gtgaccaagg cagttgctaa ggaagaggac aaggaagtcg
    67081 acatcaatag cctcaacaaa caagagcgca aagaactcgt caagaaacta gaaaaacaaa
    67141 tgcaagaagc cgtcgaagtg cttgactttg aactggcggc tcagatccgt gatatgatgt
    67201 tggaagtcaa ggccttggat taggggaata gtatgattta tttaagaaag ttaaagaaag
    67261 aagatttgat gtctttatgg gaaatggctt attcacagct taatccagtt tggaaacagt
    67321 atgatgctcc ctattatgat gattatcagt atttttcaaa ttttaaagaa ttcgaactac
    67381 aaaaatcaga atccatttta agcaactcaa atcgccttgg tatttttgtt gatgataaac
    67441 tagttgggac tgtttcgcgt tattgggtat gtaaagaaac aagatggatg gaattgggaa
    67501 ttggtattta tgataaaaaa ttctggaaca ctggtattgg gaaagttgct atgttgcagt
    67561 ggatagatag gacgtttcag gattacttgg agttggagca tctgggtttg acaacttggt
    67621 cagggaatct tggtatgatg aaacttgctg aaaaattaag aatgaaaaaa gaagctcata
    67681 ttccaaaagt tcgttattat caaggtaaat attttgatag tattaaatat ggtattttga
    67741 gagaagactg ggagaaaata aatgacggtt attatcaaat caatggaaac tcctgaagag
    67801 atagaaggta aatccctcgt tcactggcaa acgtggagag aggcttatga tgaccttttg
    67861 cctgcagaat ttcaggagac aatgacatta gaaagatgtc gattctttag tcaaaagtat
    67921 ccagaaaata cattgattgc gataggtgat ctgaaggtag ttggttttat cagttatggt
    67981 aactttcgtg atgatactat tcaagctggt ggaattattg ctttatatgt tttaaaagac
    68041 tattacggaa aaggcatagc acaaaagtta atgaaagcag ctttgactgc tcttaatcat
    68101 ttttctgaaa ttttcttatg ggtattgaaa gataacaagc gcgccattgc tttctatcaa
    68161 aaaatgggtt ttacttttga tggacaagaa aaaatacttg aacttggaaa gcctataaag
    68221 gaaaaacgaa tggtgttcta ttctaaataa ttttaaaaaa gtaaaagata atatctctgg
    68281 tagtaagtct gaaaatttaa taaattagaa agcgagtaaa tttatgtccc gttcccaatt
    68341 aacaatttta acaaatatct gtctgattga agacctcgaa acgcagcgcg tggtgatgca
    68401 gtatcgcgcc cctgaaaaca atcgctggtc tggttatgcc tttcctggag gtcatgtaga
    68461 aaatgatgag gcttttgcgg agtctgtcat tcgtgaaatc tacgaagaaa cagggttgac
    68521 tatccaaaat cctcaacttg tcggcattaa aaattggcca ctagatacag gtgggcgcta
    68581 tattgtcatt tgttataagg cgactgagtt ctctggtacc cttcaatctt cagaagaggg
    68641 agaagtttct tgggtgcaaa aagaccagat tccaaactta aatctggcct atgatatgct
    68701 accattgatg gaaatgatgg aagctcccga caagtcagag tttttctacc ctcgccgtac
    68761 agaagacgat tgggaaaaga aaatcttcta gtcttttact aaataaccta gctgatccaa
    68821 ggcctcctcg atatagtgga ggtcttgttg tgtttcggct tcgactaggt ggtaatggat
    68881 gccatctgtc aattcagata gaggtctaaa gtcagaatgc tcgacttgtt ctagaaaatg
    68941 ttgcacatct ctgcgacaag acagtttaag caaggtttca atttctccat aaacgggatg
    69001 gtcaatcaag gtattctgga catgcccacc attatcgaca atagcaagga gttcctgacc
    69061 gatttcttca acttcatgtt tcactttgaa aagtttgtga acataaggat tggtatcaat
    69121 ttgcttatag atgtagccac gattggtgga taggatagga gcgccatcgg ctctcaaaat
    69181 tgcaatgtcc tgcacaatga cctgacgtgt gacatgaaaa tgttccgcca aactttggcc
    69241 attaagggct ttaggagctt ctttcaagag ttggagcagg gcttgtttgc gatcttttgt
    69301 catagctttt ccttttaacg gcgttttcga agcactttat agacagctag tgctaatgta
    69361 tagtctacca tactatggat aattgtgcca aatccaacta gtacaaatag aacatagaac
    69421 atgttttcta cattggtacc cgaagttgcg taaaaaagga cacaggctaa tacttcagca
    69481 agggcatgaa caacagccaa aacaaaattg aaaacccagg aagattttgg tttatctagg
    69541 gtatcgggga atttttgtag gtaaagagct cctaaagcac caaaagatat atgggaaaaa
    69601 gcccgaaaaa cgataaccat gggatagcca gccatcaaaa atccaaaact agaggctagg
    69661 atgacaaaaa ctgccatcaa gggcgacaag aacatggcta taaaaatagc gatgtggctc
    69721 cccaaagtat aggaagcagg tggaatgaca atcttgaaag gcataacaat tggaatcaaa
    69781 atcgcaatag ccgttaaaag ggctgtcatt gtcataaatt gtgtcttttt ccgtgtattc
    69841 acaagaatct cctttttaac tgcatataca ctagtatggt acaataaacc agacaataaa
    69901 gcaagaattt acttgggttt atagatcatt ttttagttaa aagttatagt agattgaaac
    69961 t
//
LOCUS       DAVBNZ010000003        68088 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000003 DAVBNZ010000000
VERSION     DAVBNZ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.003"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ860_000148"
     CDS             <1..116
                     /locus_tag="VQ860_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3118651.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVASLK"
     gene            135..1652
                     /locus_tag="VQ860_000149"
     CDS             135..1652
                     /locus_tag="VQ860_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3118652.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            1777..3105
                     /locus_tag="VQ860_000150"
     CDS             1777..3105
                     /locus_tag="VQ860_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3118653.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            3358..4224
                     /locus_tag="VQ860_000151"
     CDS             3358..4224
                     /locus_tag="VQ860_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3118654.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            4240..5079
                     /locus_tag="VQ860_000152"
     CDS             4240..5079
                     /locus_tag="VQ860_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3118655.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            5351..5803
                     /locus_tag="VQ860_000153"
     CDS             5351..5803
                     /locus_tag="VQ860_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3118656.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            5900..6244
                     /locus_tag="VQ860_000154"
     CDS             5900..6244
                     /locus_tag="VQ860_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118657.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            6528..7172
                     /locus_tag="VQ860_000155"
     CDS             6528..7172
                     /locus_tag="VQ860_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3118658.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            7341..8258
                     /locus_tag="VQ860_000156"
     CDS             7341..8258
                     /locus_tag="VQ860_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3118659.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            8276..9160
                     /locus_tag="VQ860_000157"
     CDS             8276..9160
                     /locus_tag="VQ860_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3118660.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(9176..10027)
                     /locus_tag="VQ860_000158"
     CDS             complement(9176..10027)
                     /locus_tag="VQ860_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET3118661.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLIDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ860_000159"
     CDS             10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ860_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET3118662.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGN
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            12295..12891
                     /gene="recR"
                     /locus_tag="VQ860_000160"
     CDS             12295..12891
                     /gene="recR"
                     /locus_tag="VQ860_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET3118663.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            13086..14129
                     /locus_tag="VQ860_000161"
     CDS             13086..14129
                     /locus_tag="VQ860_000161"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET3118664.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFAKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            14213..15586
                     /locus_tag="VQ860_000162"
     CDS             14213..15586
                     /locus_tag="VQ860_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET3118665.1"
                     /translation="MKLTIYEVAQAVGAKNDVSLFADAQLEKAEFDSRLIGTGDLFVP
                     LKGALDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQIILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            15573..16184
                     /locus_tag="VQ860_000163"
     CDS             15573..16184
                     /locus_tag="VQ860_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3118666.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDFLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            16275..16979
                     /locus_tag="VQ860_000164"
     CDS             16275..16979
                     /locus_tag="VQ860_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET3118667.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ860_000165"
     CDS             17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ860_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET3118668.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ860_000166"
     CDS             18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ860_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET3118669.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            19852..20523
                     /locus_tag="VQ860_000167"
     CDS             19852..20523
                     /locus_tag="VQ860_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET3118670.1"
                     /translation="MNVKENTELVFREVGEASLSAHRESSSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            20533..21072
                     /locus_tag="VQ860_000168"
     CDS             20533..21072
                     /locus_tag="VQ860_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET3118671.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSVGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            21072..21335
                     /locus_tag="VQ860_000169"
     CDS             21072..21335
                     /locus_tag="VQ860_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET3118672.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            21332..22117
                     /locus_tag="VQ860_000170"
     CDS             21332..22117
                     /locus_tag="VQ860_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET3118673.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELNLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLFQDKGQTKKEKKKITVQLLLSK"
     gene            22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ860_000171"
     CDS             22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ860_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET3118674.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            23262..26054
                     /locus_tag="VQ860_000172"
     CDS             23262..26054
                     /locus_tag="VQ860_000172"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET3118675.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKNLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAAVSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            26457..26837
                     /locus_tag="VQ860_000173"
     CDS             26457..26837
                     /locus_tag="VQ860_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118676.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            27031..27321
                     /locus_tag="VQ860_000174"
     CDS             27031..27321
                     /locus_tag="VQ860_000174"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118677.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            27372..28064
                     /locus_tag="VQ860_000175"
     CDS             27372..28064
                     /locus_tag="VQ860_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET3118678.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            28117..30528
                     /locus_tag="VQ860_000176"
     CDS             28117..30528
                     /locus_tag="VQ860_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3118679.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            30778..31479
                     /locus_tag="VQ860_000177"
     CDS             30778..31479
                     /locus_tag="VQ860_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118680.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            31481..34189
                     /locus_tag="VQ860_000178"
     CDS             31481..34189
                     /locus_tag="VQ860_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3118681.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ860_000179"
     CDS             complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ860_000179"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET3118682.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ860_000180"
     CDS             complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ860_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET3118683.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(35860..36708)
                     /locus_tag="VQ860_000181"
     CDS             complement(35860..36708)
                     /locus_tag="VQ860_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3118684.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(36705..37427)
                     /locus_tag="VQ860_000182"
     CDS             complement(36705..37427)
                     /locus_tag="VQ860_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3118685.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            37718..39610
                     /gene="pepO"
                     /locus_tag="VQ860_000183"
     CDS             37718..39610
                     /gene="pepO"
                     /locus_tag="VQ860_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET3118686.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(39733..40362)
                     /locus_tag="VQ860_000184"
     CDS             complement(39733..40362)
                     /locus_tag="VQ860_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3118687.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            41358..43580
                     /locus_tag="VQ860_000185"
     CDS             41358..43580
                     /locus_tag="VQ860_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET3118688.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            43610..44053
                     /locus_tag="VQ860_000186"
     CDS             43610..44053
                     /locus_tag="VQ860_000186"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET3118689.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGFLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(44320..44505)
                     /locus_tag="VQ860_000187"
     CDS             complement(44320..44505)
                     /locus_tag="VQ860_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118690.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRELTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(44524..44937)
                     /locus_tag="VQ860_000188"
     CDS             complement(44524..44937)
                     /locus_tag="VQ860_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118691.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLD
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGILTIDFLFFVLLAFISSQRFSSLMP
                     IITARHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            complement(45068..45715)
                     /locus_tag="VQ860_000189"
     CDS             complement(45068..45715)
                     /locus_tag="VQ860_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HET3118692.1"
                     /translation="MVVGIAIASGYLNSRLHKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQE
                     GRPNQMSQKQVKLAPIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVRNDEEVR"
     gene            complement(45741..45932)
                     /locus_tag="VQ860_000190"
     CDS             complement(45741..45932)
                     /locus_tag="VQ860_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118693.1"
                     /translation="MSRKSTNFSSPLPTLKVLFSGFYFYHFILLSFGVRIFEKNGRIF
                     EKKKGSLTYEKITKNFCYI"
     gene            complement(45913..46563)
                     /locus_tag="VQ860_000191"
     CDS             complement(45913..46563)
                     /locus_tag="VQ860_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET3118694.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            46675..47517
                     /locus_tag="VQ860_000192"
     CDS             46675..47517
                     /locus_tag="VQ860_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3118695.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            47593..48030
                     /locus_tag="VQ860_000193"
     CDS             47593..48030
                     /locus_tag="VQ860_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET3118696.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            48098..48400
                     /locus_tag="VQ860_000194"
     CDS             48098..48400
                     /locus_tag="VQ860_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118697.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(48491..49564)
                     /locus_tag="VQ860_000195"
     CDS             complement(48491..49564)
                     /locus_tag="VQ860_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET3118698.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            49720..50397
                     /locus_tag="VQ860_000196"
     CDS             49720..50397
                     /locus_tag="VQ860_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3118699.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            50390..51364
                     /locus_tag="VQ860_000197"
     CDS             50390..51364
                     /locus_tag="VQ860_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3118700.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALVFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ860_000198"
     CDS             complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ860_000198"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET3118701.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFIISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVNYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(53414..53737)
                     /locus_tag="VQ860_000199"
     CDS             complement(53414..53737)
                     /locus_tag="VQ860_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET3118702.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            54596..55225
                     /locus_tag="VQ860_000200"
     CDS             54596..55225
                     /locus_tag="VQ860_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET3118703.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ860_000201"
     CDS             55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ860_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET3118704.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            56451..57065
                     /locus_tag="VQ860_000202"
     CDS             56451..57065
                     /locus_tag="VQ860_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET3118705.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(57358..58107)
                     /locus_tag="VQ860_000203"
     CDS             complement(57358..58107)
                     /locus_tag="VQ860_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET3118706.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            58240..60576
                     /locus_tag="VQ860_000204"
     CDS             58240..60576
                     /locus_tag="VQ860_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET3118707.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            61105..62568
                     /locus_tag="VQ860_000205"
     CDS             61105..62568
                     /locus_tag="VQ860_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3118708.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            62561..62989
                     /locus_tag="VQ860_000206"
     CDS             62561..62989
                     /locus_tag="VQ860_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3118709.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            62967..63416
                     /locus_tag="VQ860_000207"
     CDS             62967..63416
                     /locus_tag="VQ860_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3118710.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            63444..63755
                     /locus_tag="VQ860_000208"
     CDS             63444..63755
                     /locus_tag="VQ860_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET3118711.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            63781..64866
                     /locus_tag="VQ860_000209"
     CDS             63781..64866
                     /locus_tag="VQ860_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HET3118712.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            64877..65572
                     /locus_tag="VQ860_000210"
     CDS             64877..65572
                     /locus_tag="VQ860_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3118713.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLKSTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            65609..67579
                     /gene="tkt"
                     /locus_tag="VQ860_000211"
     CDS             65609..67579
                     /gene="tkt"
                     /locus_tag="VQ860_000211"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3118714.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            67952..>68088
                     /locus_tag="VQ860_000212"
     CDS             67952..>68088
                     /locus_tag="VQ860_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3118715.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YG"
BASE COUNT        20138 a        12447 c        15286 g        20217 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgccattac tagaccaaaa gagattacag aacgcttcgt tgctagtctt aaataagatg
      121 tgagagggag ttttatgttt aaagttttac aaaaagttgg aaaagctttt atgttaccta
      181 tagctatact tcctgcagca ggtctacttt tggggattgg tggtgcactt tcaaacccaa
      241 ccacgatagc aacttatcca atactagaca atagtatttt tcaatcaata ttccaagtaa
      301 tgagctctgc aggagaggtt gtattcagta atttgtcact acttctctgt gtgggattat
      361 gtattggctt agcgaaacga gataaaggaa ccgctgcgtt agcaggagta actggttact
      421 tagttatgac tgcaacgatc aaagctttgg taaaactttt tatggcagaa ggatctgcaa
      481 ttgatactgg agttattgga gcattagttg tcggaatagt tgccgtatat ttgcacaacc
      541 gatataacaa tattcaatta ccttccgctt taggattctt tggaggttca cgcttcgttc
      601 ctattgttac atcgttctct tctatcttga ttggctttgt cttctttgtt atttggccac
      661 ctttccaaca acttcttgtt tctacaggtg gatatatttc tcaggcgggt ccaattggaa
      721 cttttctata tggattttta atgagacttt ctggagcagt aggcttacat catataattt
      781 accctatgtt ttggtatact gaacttggtg gtgttgagac tgttgcagga caaacagtgg
      841 ttggagctca aaaaatattt tttgctcaat tagccgatcc ggcccattct ggattattta
      901 cagaaggaac aaggtttttt gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg
      961 cctgtttagc gatgtaccat agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt
     1021 tttttggagt tgctttaaca tcttttatta ccggtattac agaaccaatt gaatttatgt
     1081 ttctattcgt cagtccggtt ctatatgttg ttcacgcatt ccttgatggt gttagcttct
     1141 ttattgcaga cgtcttaaat atttcaatag gaaacacatt ttcaggaggt gtaatcgatt
     1201 tcactttatt tggaattttg caggggaacg ctaagacgaa ttgggttctt cagattccaa
     1261 ttggacttat ttggagtgtt ttgtattata ttatttttag atggttcatt actcaattca
     1321 acgttctaac gccaggacga ggagaagaag tagattctaa agaaatttct gaatccgcag
     1381 attcaacttc aaatactgca gattatttaa aacaggatag cctacaaatt atcagagcct
     1441 tgggtggatc aaataatata gaagatgtag atgcttgtgt gacacgttta cgtgtagctg
     1501 taaaagaagt taatcaagtt gataaagcac ttttaaaaca aattggtgca gttgatgtct
     1561 tagaagtgaa gggtggcatt caagcaatct atggagcaaa agcaatctta tataaaaata
     1621 gtattaatga aattttaggt gtagatgatt aagtacttac tgacttaata aaaaacagag
     1681 gagagtgatg gatgagtagg atgaaatgaa atcgcataca agaaataaag aactcattat
     1741 ccaagttgga tacgcttatt acataggaga atacaaatga aatttagaaa attagcttgt
     1801 acagtacttg cgggtgctgc ggttcttggt cttgctgctt gtggcaattc tggcggaagt
     1861 aaagatgctg ccaaatcagg tggtgacggt gccaaaacag aaatcacttg gtgggcattc
     1921 ccagtattta cccaagaaaa aactggtgac ggtgttggaa cttatgaaaa atcaatcatc
     1981 gaagcgtttg aaaaagcaaa cccagatata aaagtgaaat tggaaaccat cgacttcaag
     2041 tcaggtcctg aaaaaatcac aacagccatc gaagcaggaa cagctccaga cgtactcttt
     2101 gatgcaccag gacgtatcat ccaatacggt aaaaacggta aattggctga gttgaacgac
     2161 ctcttcacag atgaatttgt taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa
     2221 gctggagaca aggcttatat gtatccgatt agttctgccc cattctacat ggcaatgaac
     2281 aagaaaatgt tagaagatgc tggagtagca aaccttgtaa aagaaggttg gacaactgat
     2341 gattttgaaa aagtattgaa agcacttaaa gacaagggtt acacaccagg ttcattgttc
     2401 agttctggtc aagggggaga ccaaggaaca cgtgccttta tctctaacct ttatagcggt
     2461 tctgtaacag atgaaaaagt tagcaaatat acaactgatg atcctaaatt cgtcaaaggt
     2521 cttgaaaaag caactagctg gattaaagac aatttgatca ataatggttc acaatttgac
     2581 ggtggggcag atatccaaaa ctttgccaac ggtcaaacat cttacacaat cctttgggca
     2641 ccagctcaaa atggtatcca agctaaactt ttagaagcaa gtaaggtaga agtggtagaa
     2701 gtaccattcc catcagacga aggtaagcca gctcttgaat accttgtaaa cggatttgca
     2761 gtattcaaca ataaagacga caagaaagtc gctgcatcta agaaattcat ccagtttatc
     2821 gcagatgaca aagagtgggg acctaaagac gtagttcgta caggtgcttt cccagtccgt
     2881 acttcatttg gaaaacttta tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa
     2941 tactactcac catactacaa cactattgat ggatttgctg aaatgagaac gctttggttc
     3001 ccaatgttgc aatctgtatc aaatggtgac gaaaaaccag cggatgcttt gaaagccttc
     3061 actgaaaaag caaacgaaac aatcaaaaaa gctatgaaac aatagtcctt agttattcta
     3121 tgaaaaagta attttttaaa gaacctaaga gtgtataccc ccttttccct ctacacagat
     3181 agtgtaagaa aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa
     3241 gttcttacat aagcgaatca taaaaaattt cattttgatt ttaaaacagt tcaagaaagt
     3301 caaaaaatta ttctatttga aagagaggtg ccgactgtga aagtcaataa aatccgtatg
     3361 cgggaaacag tgatttccta cgctttccta gcaccagtat tattcttctt tgtcatcttt
     3421 gtgttggctc cgatggtgat gggcttcatt acaagtttct ttaactactc aatgactaaa
     3481 tttgagtttg tgggcttaga taactatatc cgtatgttta aagatcctgt ctttacaaaa
     3541 tctctgatta acacagttat tttggttatt ggatctgtac cagttgttgt tctattctca
     3601 ctctttgtag catctcagac ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc
     3661 gtcttcttcc ttcctgttgt aacgggtagt gttgccgtga cagttgtttg gaaatggatt
     3721 tatgacccac tatcagggat tctaaacttt gtccttaagt caagccacat catcagccaa
     3781 aacatttctt ggttgggaga taaaaactgg gcattgatgg cgattatgat tattctcttg
     3841 accacttcag ttggtcagcc catcatcctt tatatcgctg ccatggggaa tattgacaat
     3901 tcactggttg aagcggcgcg tgttgatggt gcaactgagt ttcaagtttt ctggaagatt
     3961 aaatggccaa gccttcttcc aacaactctt tatattgcaa tcatcacaac aattaactca
     4021 ttccagtgtt tcgccttgat tcagcttttg acatctggtg gtccaaacta ctcaacaagt
     4081 accttgatgt actaccttta cgaaaaagcc ttccaattga cagaatacgg ctatgccaac
     4141 acaattggtg tcttcttggc agtcatgatt gctatcgtaa gctttgttca atttaaagta
     4201 cttggaaacg acgtagaata ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa
     4261 ccattaacag cctttactgt tatttcaaca atcattttgc tcttgttgac tgtgctgttc
     4321 atctttccat tctactggat tttgacaggg gcattcaaat cacaacctga tacaattgtt
     4381 attcctcctc agtggttccc taaaatgcca accatggaaa acttccaaca actcatggtg
     4441 cagaaccctg ccttgcaatg gatgtggaac tcagtattta tctcattggt aaccatgttc
     4501 ttagtttgtg caacctcatc tctagcaggt tatgtattgg ctaaaaaacg tttctatggt
     4561 caacgcattc tatttgctat ctttatcgct gctatggcgc ttccaaaaca agttgtcctt
     4621 gtaccattgg tacgtatcgt caacttcatg ggaatccacg atactctctg ggcagttatc
     4681 ttgcctttga ttggatggcc attcggtgtc ttcctcatga aacaatttag tgaaaatatt
     4741 cctacagagt tgcttgaatc agctaaaatc gacggttgtg gtgagattcg taccttctgg
     4801 agtgtagcct tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt taccttcatc
     4861 aatacttgga atgactactt catgcaattg gtaatgttga cttcacgtaa caatttgacc
     4921 atctcacttg gggttgcgac catgcaggct gaaatggcaa ccaactatgg tttgattatg
     4981 gcaggagctg cccttgctgc tgttccaatc gtcacagtct tcctagtctt ccaaaaatcc
     5041 ttcacacagg gtattactat gggagcggtc aaaggataat actctgagaa aatctcttca
     5101 aactacgtca gcgtcacctt gccatactta agtattgcct gcggttagct tcctagtttg
     5161 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
     5221 tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg cagttacttt
     5281 atgaagtttt gtcagacact tataaactta agaatggttt tagttaacta tcagaaacga
     5341 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
     5401 caatttagac aaggctatcg actatctcta ccaacatcgt aaagattcat tcgaattagg
     5461 aaagtatgag attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
     5521 agttgagaat aatcaatttg aacaccataa gaactatgca gatttgcatt tgctggtaga
     5581 aggacatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag cattcgacga
     5641 agcgactgac attggctttg ttcattgtca tgaacactac ccactcttgt tgggttatca
     5701 taattttgcg attttcttcc caggtgagcc acatcagcca actggctatg caggtatgga
     5761 agaaaaggtt cgaaaatatc tctttaaaat tttgattgat taaaaatagg atgaattgtt
     5821 tttttgtaaa gctttgacaa tactctacca tgaaattgat ctttgtgagg tagagaaatg
     5881 agaataaaat atttaaaaat tggtatcttc taagcatgct gcaagagcta gtttcttaga
     5941 tggacagggg attacagttg atgagatgtc ctggataatt aatggcattg tgaatgcatt
     6001 gattggtaga tacataaaat taggtactta tgcagctaag tatggtatta gtatagcacg
     6061 ctcgatctta agtagggcag ctgcaactgc agcagcaaga gtaggattac tgaccaagat
     6121 ttctggatgg attttacgag tagctgtgaa tgtagctgat gtatatggta attttgccaa
     6181 caatattgct gcagcttggg atgcatatga taaaattcct aacaatggtc gtataaactt
     6241 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
     6301 gcttgcaatg ataattcgtg gagggctaga tggatttgat aggcatactt ggagtactat
     6361 tttaattgct tcgctgttcg gggtatatga ttataagccc atagataaaa atagaaaaaa
     6421 gtccaaaaga aaaaagaaaa aatagatttg ttcatggtag ggacttatga aagctttact
     6481 gacaaaaaag aaaacagttt acaaagaaaa atgatggagg agcaaacatg gcacaaaaag
     6541 gagtaagcct tatcaaggca gcatttgata cagataactt tctcatgcgt tttagtgaga
     6601 aggtcttgga catcgtgaca gccaatcttc tttttgtcgt ctcttgtttg cccatcgtga
     6661 cgattggagt ggctaaaatc agcctctacg agaccatgtt cgaagttaag aagagcagac
     6721 gggtgcctgt ttttaaaatc tatctaagat ctttcaagca aaatctgaaa ctaggtcttc
     6781 agttaggtct gcttgagttg ggcattgttt cattaagcct cctagatctt tatctctttt
     6841 ggggtcaaac agctctgccc tttcaattgc tgaaagctat ttgtctaggc attctgattt
     6901 tccttacgat tgtgatgttg gctagctatc caatcgcggc acgttatgat ttaacttgga
     6961 aagaaattct tcaaaaagga ttgatgttgg ctagttttaa ctttccttgg ttcttcctca
     7021 tgttagccat tcttgtcctc attgtgatgg ttctttatct gtctgccttc agtctactct
     7081 taggtggctc agtcttcctg ctttttgggt ttggactatt ggtctttatc cagactggat
     7141 tgatggagaa aattttcgca aaataccaat aggagcctta tttctgaaac tactttcaaa
     7201 ggctccaaac gctattctat aagcgagaaa ctaaaatcta agtgtctata agatattgaa
     7261 agccttttcg gtaaagtgta tactaaagaa gtaaagaaaa atctgcttta gcagaaaata
     7321 aaaataatag gagaaaatct atgtcagatt tgaaaaaata cgaaggtgtc attccagcct
     7381 tctacgcatg ttatgatgag caaggagaag taagtccaga gcgtacgcgt gccttggttc
     7441 aatacttcat tgataaaggt gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta
     7501 tctaccaaag cgttgaagat cgcaagttga ttttggaaga agtcatggcg gtagccaaag
     7561 gtaaattgac cattattgcc catgttgctt gcaataatac taaagatagt atggaacttg
     7621 ctcgccatgc tgaaagcttg ggagtagatg ctattgcaac gattccacca atttacttcc
     7681 gcttgccaga atactcagtt gccaaatact ggaacgatat tagttctgca gctccaaaca
     7741 cagactacgt gatttacaac attcctcaat tggcaggggt tgctttgact ccaagccttt
     7801 acacagaaat gttgaaaaat cctcgtgtta tcggtgttaa gaactcttct atgccagttc
     7861 aagatatcca aacctttgtc agccttggcg gggaagacca tattgtcttt aacggtccag
     7921 atgaacagtt cctaggtggc cgcctcatgg gtgctaaggc tggtatcggt ggtacttatg
     7981 gtgctatgcc agaactcttc ttgaaactca atcagttgat tgcggataag gacctagaaa
     8041 cagcgcgtga attgcagtat gctatcaacg caatcattgg taaactcact tctgctcatg
     8101 gaaatatgta cggtgtcatc aaagaagtct tgaaaatcaa tgaaggcttg aatattggat
     8161 ctgttcgttc accattgaca ccagtaactg aagaagatcg tccagttgta gaagcggctg
     8221 cagccttgat tcgtgaaacc aaggagcgct tcctctaatc taaaaggagg tatttatgac
     8281 atactacgtt gcaattgata tcggtggaac taacatcaag tatggtttgg ttgatcaaga
     8341 ggggcaactt cttgaatcgc atgaaatgcc aactgaggcg cataagggtg gacctcatat
     8401 cttacaaaag accaaagata tcgtagctag ttatttagaa aaaggcccag tagcaggtgt
     8461 tgccatatct tctgctggga tggtggatcc ggataagggt gagattttct atgctgggcc
     8521 gcaaatccct aactacgcag gcacccagtt caaaaaggaa atcgaagaaa gctttactat
     8581 tccttgtgag attgaaaatg atgtcaactg tgcaggtctt gctgaggcag tatctggttc
     8641 aggcaaggga gcaagtgtga cactttgctt gaccattgga acaggtatcg gtggttgctt
     8701 gattatggat aggaaagtct tccatggttt tagtaattca gcctgtgaag tcgggtatat
     8761 gcatatgcag gatggagctt ttcaagactt ggcttctaca acagctttag tgaaatatgt
     8821 agctgaagcc catggagaag atgttgatca gtggaatggc cgacgtatct ttaaggaagc
     8881 tactgaagga aacaaaatct gcatggaagg tattgaccgt atggttgact atctaggaaa
     8941 aggtctggca aatatttgct acgttgccaa tccagaagtg gttattcttg gtggtggtat
     9001 catggggcaa gaggctatcc tcaaacctaa gatccgcaca gccttgaaag aggctttggt
     9061 accaagttta gcagaaaaaa cacgattaga atttgcccat caccaaaata cagcagggat
     9121 gttgggtgca tattatcatt ttaagacaaa acaatcctag tttggctcag ccaaactagg
     9181 attttcttac acgtttttgt ctacgatagc cgttgagttt tttattttcc cagtagctat
     9241 taaagatttt ttccttgctt tcgcgattga tttccaaaaa gtaggcataa atcaaatcga
     9301 taaagaagag cataggaagt tgagcggata ttcgttggat ataggagggt tggctgtggg
     9361 tggctacaag aacagtctct gtataggtct ggctatcttt attgggaaca cttgtaaaga
     9421 gtacagtctt tgcccccatc tccttggcat ctattagact atctaaaata gaaggagttg
     9481 agcctgaaag tgagaagccc agtactagac aattttcatc catgatgctg gttgtccagg
     9541 caaagccgtc ttggtctgtc aaagcttcgc agaccacacc tagtcgcata aaacgtaatt
     9601 tcatttcacg ggcgacgagg ccagaactcc ctgttccgaa gaagtagata cgctcagcat
     9661 cttcgattag ctgggcaatt cgttctagtt ggatttcgtc aatcaagtct tgtgtttgtt
     9721 ccctcatgtt gctataactt ctgaggactc gtttggtcag tggactgtgc ttggagactt
     9781 ggttggcttg attttctgcc tgatgttggt attggaaaat aaattctcgg tagccagtaa
     9841 agccacactt tttagcaaag cgggtcaaag cagcttgaga aatatgtaat ttttgggtga
     9901 cttgttgaga agataaatca tctgtaatcg tttcagcttg caaaaaatag cgagcgattt
     9961 cttgttctag gtctgtcatt tcttcaaaat gtgaatcaat gatagttgcg atatctggtt
    10021 tgtccatagg gaaagctcct ttacatgagt catactggaa gactagatca gggaatagtc
    10081 acacttcatt ataacacata atataaggat agataaataa aaacgcatct ctgttttaaa
    10141 aacgaaaaaa tcgaaaaagc ttctctcttt tccataattt tctactcaaa ttgtggtaca
    10201 attaagagta agattttaag ttagaaatga gactgatttg tatgagaaaa tttaacagcc
    10261 attcgattcc gattcggctt aatttattgt tttcaatcgt cattttactc tttatgacca
    10321 ttattggtcg tttgttgtat atgcaggttt tgaacaagga tttttacgaa aaaaagctag
    10381 cctcagctag tcagaccaag attacaagca gttcagcccg tggggaaatt tatgatgcta
    10441 gtggaaaacc tttggtagaa aatacgttaa agcaggttgt ttcctttacg cgtagcaata
    10501 aaatgacagc tacagactta aaagaaacag ctaaaaagtt actgacttat gtgagcatca
    10561 gttctccaaa tttgacagaa cgccagctgg cggattacta tttggctgat cctgaaatct
    10621 ataaaaaaac agtggaagct ctcccaagcg agaaacgctt ggattcagat ggcaatcgtc
    10681 tatccgaatc agaactgtat aacaatgcgg tcgatagtgt acaaacgagt caactaaact
    10741 atacagagga tgaaaagaaa gaaatctatc tttttagtca gttaaatgct gttggaaact
    10801 ttgcgacagg aaccattgcg acagatcctc taaatgattc tcaggtggct gttattgcct
    10861 ctatttcaaa ggagatgcct ggcattagta tttctacttc ttgggataga aaggttttgg
    10921 aaacttccct ttcttctata gttgggagtg tatccagtga aaaagctggt ctcccagcgg
    10981 aagaagcaga agcctatctt aaaaaaggct attctctaaa tgatcgtgta ggaacttcct
    11041 atttggaaaa gcaatatgaa gagaccttac aaggaaaacg ctcggtaaaa gaaatccatc
    11101 tggataaata tggcaatatg gaaagcgtgg atacaattga ggaaggtagt aagggaaaca
    11161 atatcaaact gaccattgat ttggctttcc aagatagcgt ggatgcttta ctgaaaagtt
    11221 atttcaattc cgagctagaa aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg
    11281 cccttaaccc aaaaacaggt gcggttttgt ctatgtcagg gattaaacat gacttgaaaa
    11341 cgggagagtt gacgcctgat tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg
    11401 ttgtcaaggc ggcgaccatc agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga
    11461 ccttgacaga ccagtccatt gtcttccaag gttcagctcc catcaattct tggtatactc
    11521 aggcttacgg ttcattccct atcacagcgg tccaagctct ggagtattca tcaaatacct
    11581 atatggtcca aacagcctta ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg
    11641 gcaccagcaa tctagagtct gctatggaga aactgcgttc aacctttggc gaatatggct
    11701 tgggtactgc gacaggaatt gacctaccag atgaatctac tggatttgtt cccaaagagt
    11761 atagctttgc taattacatt actaatgcct ttgggcagtt tgataactat acgccgatgc
    11821 agttggctca gtatgtagca actattgcaa ataatggtgt tcgtgtggct cctcgtattg
    11881 ttgaaggcat ttatggtaat aatgataagg gaggactggg taacttgatt cagcaactgc
    11941 aaccgacaga gatgaataag gtcaatatat ccgactccga tatgagcatc ttgcaccaag
    12001 gtttttatca ggttgcccat ggtactagtg gattgacaac tggacgtgcc ttttcaaatg
    12061 gtgccttggt atccattagc ggaaaaacag gtacagccga aagctatgtg gcagatggtc
    12121 agcaagcaac caataccaat gcggtggcct atgccccatc tgataatccc caaatcgctg
    12181 tcgcagtggt ctttcctcat aataccaatc taacaaatgg tgtaggacct tccattgcgc
    12241 gtgacattat caatctgtat caaaaatacc atccaatgaa ttagaaagga aattatgctt
    12301 tatccaacac ctattgccaa gttgattgac agttattcta agttaccagg tatcgggatt
    12361 aagacggcta cgcgtctggc cttttatacg attgggatgt ctgctgatga tgtcaatgaa
    12421 tttgcaaaaa atctcctttc tgctaagaga gaattgacat attgttctat ttgtggacgt
    12481 ttgacagacg acgatccttg ttctatctgt actgatccga ctcgtgacca gacaacaatt
    12541 ttagttcttg aggatagtag agatgtggca gccatggaaa atatccaaga ataccatgga
    12601 ctctatcatg tccttcatgg cctcatttct cctatgaatg gtatcagtcc ggacgatatc
    12661 aatctcaaga gccttatgac tcgtcttatg gatagtgagg tttcagaagt gattgtggcg
    12721 actaatgcta cagcggatgg tgaagcgact tccatgtatc tttcacgttt gctcaagccg
    12781 gctggtatca aggttacgcg tctagcacga ggtctcgctg tgggagcgga cattgagtat
    12841 gcggacgaag tgacactctt acgagcgatt gaaaatcgga cagagttgta agtgtaggca
    12901 aatttacgaa ctccattcat ttataaaaaa tcaaagaggc tgaaaatcgt tcctatcggc
    12961 ctctttttgt atagtgtgat gagtaggatc aggttcaagt tttaaaaaac caagcaaata
    13021 tgatatacta aagagcgagt attctagtag aattaggaca aataagtaga attaggacaa
    13081 ataatatgaa acaaacgatt attcttttat atggtggacg gagtgcggaa cgcgaagtct
    13141 ctgtcctttc agctgagagt gtcatgcgtg cggtcaatta cgaccgtttc acagtcaaga
    13201 ctttctttat cagtcagtca ggtgacttta tcaaaacaca ggaatttagt catgctccgg
    13261 ggcaagaaga ccgtctcatg accaatgaaa ccattgattg ggataagaaa gttgcaccaa
    13321 gtgctatcta cgaagaaggt gcagtggtct ttccagtcct tcacgggcca atgggagaag
    13381 atggctctgt tcaaggattc ttggaagttt tgaaaatgcc ttacgttggt tgcaacattt
    13441 tgtcatcaag tcttgccatg gataaaatca cgactaagcg tgttctggaa tctgctggta
    13501 ttgcccaagt tccttatgtg gctatcgttg aaggcgatga tgtgactgct aaaatcgctg
    13561 aagtggaaga aaaattggct tatccagtct tcgctaagcc gtcaaacatg gggtctagtg
    13621 tcggtatttc taagtctgaa aaccaagaag aactccgtca agccttaaaa cttgccttcc
    13681 gatatgacag ccgtgtcttg gttgagcaag gagtgaatgc ccgtgaaatt gaggttggcc
    13741 tcttgggtaa ctacgatgtc aagagcacgc tacctggaga agttgtcaag gacgttgcct
    13801 tttatgacta cgatgccaag tatattgata acaagattac tatggatatt cctgccaaaa
    13861 tcagtgatga tgtggtggct gtcatgcgtc aaaatgcaga aacagccttc cgtgccattg
    13921 gtggccttgg tctatctcgt tgcgatttct tctatacaga taagggagag atttttctca
    13981 acgagctcaa taccatgcca ggtttcaccc agtggtctat gtacccacta ctttgggaca
    14041 atatggggat cagctaccca gaactaatcg agcgtttggt tgaccttgcc aaggaaagtt
    14101 ttgacaagcg cgaagcgcat ttgatataaa atgaaagaga gggtagaagc cagaaccatc
    14161 actgcaaggt gactagagtt ctcggacttc gccccttttt aaaggagtag aaatgaaatt
    14221 aacaatctat gaagttgccc aagctgttgg agctaaaaat gatgttagtc tttttgcgga
    14281 cgcccagtta gaaaaggctg agtttgacag tcgattgatt gggactggag atttatttgt
    14341 gccacttaaa ggtgcgcttg atggccatga ctttattgaa acagcctttg aaaatggtgc
    14401 agcagtaacc ttgtctgaga aagaggtctc aaatcatcct tacattctag tagatgatgt
    14461 tttgacagcc tttcaatcct tagcatccta ctatcttgaa aaaacgactg ttgatgtctt
    14521 tgctgttaca ggttcaaatg gcaagacaac gactaaggat atgttggcgc atttactgtc
    14581 aacaagatac aagacctaca aaacacaagg caattacaat aatgagattg gccttcctta
    14641 cacagttctt catatgcctg aaggaacaga aaagttggtt ttggagatgg gacaggatca
    14701 cttgggagat attcatctct tgtctgaatt ggctcgtcca aaaacagcca tcgtgacctt
    14761 ggttggagaa gctcatttgg cctttttcaa agatcgttct gagattgcta aaggaaaaat
    14821 gcaaattgca gacggaatgg cttcaggttc cttgctttta acgccggctg accctatcgt
    14881 agaggactat ttgccaactg ataaaaaggt ggtccgtttt gggcaagggg cagagttgga
    14941 aatcacagac ttggttgagc gtaaggacag tctgaccttt aaggctaatt tcttggaaca
    15001 agcccttgat ttgccagtga ctggtaagta caatgctacc aatgctatga ttgcgtccta
    15061 tgttgcccta caagaaggag tttcagagga gcaaattcat caggccttcc aaggtcttga
    15121 attgacgcgt aatcgtactg agtggaagaa agcagccaat ggagcagata tcctgtcaga
    15181 cgtatataat gccaatccaa ctgctatgaa gctgatttta gagactttct ctgccattcc
    15241 agccaatgaa ggtggcaaga aaattgcagt gttggcggat atgaaggagc ttggtgacca
    15301 gtctattcaa ctccataacc agataatttt gagcctttct ccagatgtgc ttgataccgt
    15361 tattttctat ggagaagaca ttgctgaatt agcccaactt gctagtcaaa tgttcccaat
    15421 cggacacgtt tattacttca agaaaacaga agaccaagac caatttgaag acctagttaa
    15481 gcaggtcaaa gaaagccttg gggctcatga ccaaatcctg ctcaaaggct ctaactctat
    15541 gaatctagcc aagttggtag aaagtttaga aaatgaagac aagtgatttt gtcaagtatt
    15601 tgcaaagaat gattgccatt acagatactg gcttaacctt tacaaaagat ccgtttgacc
    15661 gtgagcgcta cgaagacttg cgagactttt tatctgaaat gttgaatcaa gcatcagacc
    15721 ttgattccga agaagtggca gaagtcttga agccaacttc tgcttatgcg actccgttaa
    15781 tggacgtccg tgcttggatt gttgaggacg aaaagatttg tctggttagg ggacaaggag
    15841 aggatagttg ggctttgcca ggtggctttg gtgaggttgg ctattctcca acagaaaata
    15901 ttctcaagga aattgaagaa gaaaccggtt ttaaagccaa agttgaaaga ctgctagctg
    15961 tttttgatac caatcgtttc caactacaga gcaaacagta tacaaagttt gtttttggat
    16021 gtaagcttct cgatggacaa ttccaagaaa atcaagaaat tgctgacctt caattttttg
    16081 ccattgacca actgccgaac ttatctgaaa aacgcattac caaggagcaa atagagcttc
    16141 tttggcaggt ttatcaaggt catagggggc aatatcttga ctaagaagat gattatcgta
    16201 tttctaaatc catttttaac aactagcatg gtataataat atgcaggaaa attttgaatt
    16261 atgaggaaga ctagatgaat ttatgggata ttttctttac gactcaggca accgagccgc
    16321 ccaaatttga ccttttttgg tatgttagcc tatttacgct cttagcctta accttttata
    16381 cagcccatcg ctatcgtgaa aagaaggttt accaacgatt tttccaaatc ttgcagactg
    16441 ttcagttaat ccttctttat ggttggtact gggttaatca tatgccactg tcagaaagcc
    16501 taccctttta ccattgccgt atggctatgt ttgtggtact cttgcttcct ggtcagtcca
    16561 aatataaaca atactttgca ttattgggaa catttgggac attagcagcc tttgtttatc
    16621 cagtgccaga tgcttaccct tttccacata ttaccatttt atcctttatc tttggtcatt
    16681 tagcactctt ggggaactct ctagtttatc tattgagaca gtataatgcg cgattgctgg
    16741 atgtgaaggg aatttttctc atgacctttg ccctaaatgc cttgattttt gtggtcaatt
    16801 tggtgacagg tggcgattac ggatttttga caaaaccgcc attggttggg gatcacggtc
    16861 tagtagctaa ttatttactt gtttcaattg tgctggtagc tactatcagt ttgactaaga
    16921 aaatcttaga attcttttta gctcaagaag cagaaaaaat gattgcaaag gaagcttaac
    16981 acagagcttt cttttttgct cttagagagt ttttacaagc agcttataaa ataagaattt
    17041 ctgaatagac aaactcaaaa aatggctggg aaatttagga aaaaagcaag cacgattaaa
    17101 ttttttgtgt tataatattt tgtgaatagc tatgcctatg tttagctatg gaataatacg
    17161 aagtgcgaaa cttggaagat agagaggaag cgatgtaatg gctagagaag gcttttttac
    17221 aggtctagat attggaacaa gctctgtcaa ggtgcttgtg gccgagcaga gaaatggtga
    17281 attaaatgta attggcgtga gtaatgccaa aagtaaaggt gtaaaggatg gaattattgt
    17341 tgatattgat gcagcagcaa ctgctatcaa gtcagccatt tcccaagcgg aagaaaaggc
    17401 aggcatttcg attaaatcag tgaatgtcgg cttgcctggt aatcttttgc aggtagaacc
    17461 aactcagggg atgattccag taacatctga tactaaggaa attacggatc aagatgttga
    17521 aaatgttgtc aaatcagctt tgacaaagag tatgacacct gaccgtgaag tcattacctt
    17581 tattcctgaa gaatttattg tggatggttt ccaagggatt cgtgacccac gtggcatgat
    17641 gggggttcgc cttgaaatgc gtggtttgct ttatacagga cctcgtacta tcttgcacaa
    17701 tttgcgtaag acggttgagc gtgcaggtgt tcaggttgaa aatgttatca tttcaccact
    17761 agcaatggtt cagtctgttt tgaacgaagg ggaacgtgaa tttggtgcta cagtgattga
    17821 tatgggggca ggtcaaacga ctgtcgctac aatccgtaat caagaactcc agttcacaca
    17881 tattctccaa gaaggtggag attatgtaac taaagatatc tccaaggttt tgaaaacctc
    17941 tcgcaaatta gcggaaggct tgaaactgaa ttacggggaa gcctatccgc ctcttgcaag
    18001 caaagaaacc ttccaagtag aggttattgg agaagtagaa gcagtcgaag tgacggaagc
    18061 ctacttgtca gaaattattt ctgcacgaat caagcacatc cttgaacaaa tcaagcaaga
    18121 attagataga aggcgtctat tggacctccc tggtggtatt gtcttaatcg gtgggaatgc
    18181 cattttacca ggtatggttg agcttgctca ggaagtcttt ggcgtccgtg tcaagcttta
    18241 tgtcccaaat caagttggta tccgtaatcc agcctttgcg catgtgatta gtttatcaga
    18301 atttgcgggt caattaacag aagttaatct tttggctcag ggagcgataa aaggtgagaa
    18361 tgacttaagt catcagccaa ttagttttgg tgggatgctg caaaaaacag ctcagtttgt
    18421 acaatcaacg cctgttcaac cagctcctgc tccagaagta gagccggtgg cgcctacaga
    18481 accaatggcg gatttccaac aagcttcaca aaataaaccg aaattagcag atcgtttccg
    18541 tggcttgatc ggaagcatgt ttgacgaata aagaggaaaa ataaattatg acattttcat
    18601 ttgatacagc tgctgctcaa ggggcagtga ttaaagtaat tggtgtcggt ggaggtggtg
    18661 gcaatgccat caaccgtatg gtcgacgaag gtgttacagg cgtagaattt atcgcagcaa
    18721 acacagatgt acaagcattg agtagtacaa aagctgagac tgttattcag ttgggaccta
    18781 aattgactcg tggtttgggt gcaggaggtc aacctgaggt tggtcgtaaa gccgctgaag
    18841 aaagcgaaga aacactgacg gaagctatta gtggtgccga tatggtcttc atcactgctg
    18901 gtatgggagg aggctctgga actggagctg ctcctgttat tgctcgtatc gccaaagatt
    18961 taggtgcgct tacagttggt gttgtaacac gtccctttgg ttttgaagga agtaagcgtg
    19021 gacaatttgc tgtagaagga atcaatcaac ttcgtgagca tgtagacact ctattgatta
    19081 tctcaaacaa caatttgctt gaaattgttg ataagaaaac accgcttttg gaggctctta
    19141 gcgaagcgga taacgttctt cgtcaaggtg ttcaagggat taccgatttg attaccaatc
    19201 caggattgat taaccttgac tttgccgatg tgaaaacggt aatggcaaac aaagggaatg
    19261 ctcttatggg tattggtatc ggtagtggag aagaacgtgt ggtagaagcg gcacgtaagg
    19321 caatctattc accacttctt gaaacaacta ttgacggtgc tgaggatgtt atcgtcaacg
    19381 ttactggtgg tcttgactta accttgattg aggcagaaga ggcttcacaa attgtgaacc
    19441 aggcagcagg tcaaggagtg aacatctggc tcggtacttc aattgatgaa agtatgcgtg
    19501 atgaaattcg tgtaacagtt gttgcaacgg gtgttcgtca agaccgcgta gaaaaggttg
    19561 tggctccaca agctagatct gctactaact accgtgagac agtgaaacca gctcattcac
    19621 atggttttga tcgtcatttt gatatggcag aaacagttga attgccaaaa caaaatccac
    19681 gtcgtttgga accaactcag gcatctgctt ttggtgattg ggatcttcgc cgtgaatcga
    19741 ttgttcgtac aacagattca gtcgtttctc cagtcgagcg ctttgaagcc ccaatttcac
    19801 aagatgaaga tgaattggat acacctccat ttttcaaaaa tcgttaagta aatgaatgta
    19861 aaagaaaata cagaacttgt ttttcgagaa gttggagagg ctagtctgag tgctcatcga
    19921 gagagtagtt cggtctctgt cattgcagtt accaagtatg tagatgtacc gacagcggaa
    19981 gccttgcttc cgctaggtgt tcatcatatc ggtgaaaatc gtgtagataa gtttctggaa
    20041 aaatatgaag ctttaaaaga tcgagatgtg acttggcatt tgattggtac cttgcaaaga
    20101 cgtaaggtga aagatgtcat tcaatacgtt gattatttcc atgcattgga ctcagtaaag
    20161 ctagcagggg aaattcaaaa aagaagtgac cgagtcatca agtgtttcct tcaagtaaat
    20221 atttctaaag aagaaagcaa acacggtttt tcgagagagg aactgctgga aatcttgcca
    20281 gagttagcca gactagataa gattgaatat gttggtttaa tgacgatggc accttttgag
    20341 gctagcagtg agcagttgaa agagattttc aaggcgaccc aagatttaca aagagaaatt
    20401 caagagaaac aaattccaaa tatgcctatg accgagttaa gtatgggaat gagtcgtgat
    20461 tataaagaag cgattcaatt cggttccact tttgttcgta taggtacatc attttttaag
    20521 taggagagaa ccatgtcttt aaaagataga ttcgatagat ttatagatta ttttacggag
    20581 gatgaggatt caagtctccc ttatgaaaaa agagatgagc ctgtgtttac tccagtaaat
    20641 tcttcacagg aaccggctct cccaatgaat caaccttcac agtcggttgg tacaaaagag
    20701 aacaatatca ccagacttca tgcaagacaa caggaattgg caaatcagag tcagcgtgca
    20761 acggataagg tcattataga tgttcgttat cctagaaaat atgaggatgc aacagaaatt
    20821 gttgatttat tggcaggaaa cgaaagtatc ttgattgatt ttcagtatat gacagaggtg
    20881 caggctcgtc gttgtttgga ctatttggat ggagcttgtc atgttttagc tggaaatttg
    20941 aaaaaggtag cttctaccat gtatttgttg acaccagtga atgttattgt aaatgttgaa
    21001 gatatccgtt taccagatga agatcaacag ggtgagttcg gttttgatat gaagcgaaat
    21061 agagtacgat aatgattttt ttaattcgta tgatttataa tgcagtggat atttactccc
    21121 tgattttggt agccttcgct gtcatgtctt ggtttccagg tgcctacgaa tccagtttag
    21181 gtcgttggat tgtagcgttg gtgaaaccag tacttgctcc cttgcaacgc ctgcctttac
    21241 agatagcggg tcttgattta tctgtttggg tcgcgattgt tttggttcga tttttaggag
    21301 aaaacctagt gcgttttctg gcgatgatag gatgaataaa gggatttatc agcatttctc
    21361 catagaagat cgtccatttc ttgacaaggg aatggaatgg ataaagaagg tagaagatag
    21421 ctatgctcct tttttaactc cttttatcaa tcctcatcag gagaagctat taaagatttt
    21481 ggccaaaacc tatggtcttg cttgtagcag tagtggggaa ttcgtctcga gtgagtatgt
    21541 tcgagtttta ttatacccag attatttcca accagagttt tcagattttg aaatatctct
    21601 ccaagaaatt gtgtattcca ataaatttga acatttaacg catgctaaga ttttagggac
    21661 agtcatcaat caattaggga ttgaacggaa actttttgga gatatcctag tagatgaaga
    21721 acgggcgcag attatgatta atcagcagtt tcttcttctc tttcaagatg gactaaagaa
    21781 aattggtcgt atacctgttt cgttggagga acgtcctttc accgagaaaa tagataagct
    21841 agaacagtat cgagaactga atttatctgt gtctagtttt cgattagatg ttcttttatc
    21901 aaatgttttg aaactatcta ggaatcaagc aaaccagttg attgaaaaga aacttgtcca
    21961 agtaaattat catgtggtag acaaatcaga ttacactgtt caagttggag acttgattag
    22021 tgtgagaaaa tttggtcgct tgagattatt tcaagataag ggacaaacga aaaaagagaa
    22081 gaaaaaaata accgtccagt tattattaag taagtgagga atagaatgcc aattacatca
    22141 ttagaaataa aggacaagac ctttggaact cgattcagag gttttgatcc agaagaagtc
    22201 gatgaatttt tagatattgt ggttcgtgat tacgaagatc ttgtgcgtgc gaatcatgat
    22261 aaaaatttgc gtattaagag tttagaagag cgtttgtctt actttgatga aataaaagat
    22321 tcattgagcc agtctgtatt gattgcccag gatacagctg agagagtgaa acaggcggcg
    22381 catgaacgtt caaacaatat cattcatcaa gcagagcaag atgcgcaacg cttgttggaa
    22441 gaagctaaat ataaggcaaa cgagattctt cgtcaagcaa ctgataatgc taagaaagtc
    22501 gctgttgaaa cagaagaatt gaagaacaag agccgtgtct tccaccaacg tctcaaatct
    22561 acaattgaga gtcagttggc tattgttgaa tcttcagatt gggaagatat tctccgtcca
    22621 acagctactt atcttcaaac tagtgatgaa gcctttaaag aagtggttag cgaagtactt
    22681 ggagaaccga ttccagctcc aattgaagaa gaaccaattg atatgacacg tcagttctct
    22741 caagcagaaa tggaagaatt acaagctcgt attgaggtag ccgataaaga attgtctgaa
    22801 tttgaagctc agattaaaca ggaagtggaa actccaactc ctgtagtgag tcctcaagtt
    22861 gaagaagagc ctctgctcat ccagttggcc caatgtatga agaaccagaa gtagctccag
    22921 tgcatccgac aggtccaaca ccagctacag aaactgttga ttcagcatca ggatttgaag
    22981 caccgcaaga atccgttaca attttataag aaacgatgtg agaacaatat cttatcctta
    23041 tatttccagc gagcaggaga tggtgtgagt cctgcattcc ctaacgataa gattatcctc
    23101 tcaaaaactc aagtctgaag ctagtaagat ttgacgtttc ccacgttacg ggataagagg
    23161 gagaaagact aaatcttttt ccgaataaag gtggtaccac gattttcgtc ctttttggaa
    23221 gtcgtggttt ttaatttgtt attatttata aaggagatac catgaaactc aaagataccc
    23281 ttaatcttgg gaaaacagct ttcccaatgc gtgcaggcct tccgaccaaa gagccagttt
    23341 ggcaaaagga atgggaagat gcaaaacttt accaacgtcg tcaagaacta aatgaaggga
    23401 aaccgcattt tgtcttgcat gatggccctc catacgcaaa cggaaatatc cacgttggac
    23461 atgccatgaa tcatatctca aaagatatca tcattcgttc taagtctatg tcaggtttta
    23521 acgcacctta tatcccaggt tgggatactc atggtctgcc aatcgagcaa gttttggcaa
    23581 agcaaggtgt gaagcgcaaa gaaatggact tggttgagta cttgaaactc tgtcgtgagt
    23641 acgctctttc tcaagtttat aaacaacgtg atgatttcaa acgcttgggg atgtcaggtg
    23701 actgggaaaa tttatatgtg actttaactc cagactatga agcagcccaa atccgtgtct
    23761 ttggtgagat ggctaataag ggttatatct accgtggtgc caagccagtt tactggtcat
    23821 ggtcatctga gtcagccctt gccgaagcgg aaattgaata ccatgatttg gtttcgactt
    23881 cactttatta tgccaataag gtaaaagatg gcaaaggtat cctagataca gatacttata
    23941 tcgtagtctg gacaacaact ccatttacca tcacagcttc tcgtggtttg actgttggtg
    24001 cagatattga ttacgttttg gttcaacctg ctagtgaaac tcgtaagttt gtcgttgctg
    24061 cagaattgtt gactagcttg tctgagaaat ttggctgggc tgatgttcaa gtgttggcaa
    24121 cttaccgtgg tcaagaactc aaccacatcg taacagaaca cccatgggat acagctgtag
    24181 atgagttggt aatccttggt gatcacgtta ccactgactc tggtacaggt atcgtccata
    24241 cagcccctgg ttttggtgag gacgactaca atgttggtat tgctaatggt cttgaagtcg
    24301 cagtgactgt tgacgaacgc ggtatcatga tggcgaatgc tggtcctgag tttgaaggtc
    24361 agttctacga caaggttgta ccaactgtta ttgaaaaact tggtaacctc cttctagccc
    24421 aagaagaaat ctctcactca tacccatttg actggcgtac taagaaacca atcatctggc
    24481 gtgcagttcc acaatggttt gcctcagttt caaaattccg ccaagaaatc ttggatgcta
    24541 ttgataaagt taaattccat acagaatggg gtaaagtacg tctatataat atgattcgtg
    24601 accgtggtga ctgggttatc tctcgtcaac gtgcttgggg tgttccactt ccaatcttct
    24661 atgcagaaga cggtacagct atcatgacag ctgagactat tgaacatgtg gcgcaactct
    24721 ttgaagtaca tggttcaagc atttggtggg aacgtgatgc caaaaacctc ttaccagaag
    24781 gatttacaca tccaggttct ccaaatgggg agttcaagaa agaaacagat attatggatg
    24841 tatggtttga ctcaggttca tcatggaatg gtgttttggt aaatcgtcca aatctgactt
    24901 atccagctga cctttacctt gaaggttctg accaataccg tggttggttc aactcatcac
    24961 ttattacatc tgttgccaac catggcgtag caccttacaa acaaatcttg tcacaaggtt
    25021 ttacccttga tggtaaaggt gagaagatgt ctaaatcact tggaaatacc attgctccaa
    25081 gtgatgttga aaaacaattt ggtgcagaaa tcttgcgtct ctgggtaaca agtgttgact
    25141 caagcaatga cgtgcgtatc tctatggata ttttgagcca agtttctgaa acttaccgta
    25201 agattcgtaa cactcttcgt ttcttgattg ccaatacatc tgactttaac ccagctcaag
    25261 atgtagtcgc ttacgatgaa cttcgttcag ttgataagta catgactatt cgctttaacc
    25321 agcttgtcaa gaccattcgt gatgcctatg cggactttga attcttgaca atctacaagg
    25381 ccttggtgaa ctttatcaac gttgacttgt cagccttcta ccttgatttt gccaaagatg
    25441 ttgtttacat tgaaggtgcc aaatcattgg aacgccgtca aatgcagact gttttctatg
    25501 acattcttgt caaaatcacc aaactcttga caccaatcct tcctcacact gcggaagaaa
    25561 tctggtcata tcttgagttt gaagctgaag acttcgttca attgtcagaa ttgccagaag
    25621 ctcaaacttt tgctaatcaa gaagaagtct tggatacatg ggcagccttc atggacttcc
    25681 gtggacaagc tcaaaaagcc ttggaagaag ctcgtaatgc aaaagttatc gggaaatcgc
    25741 ttgaagcaca cttgacagtt tatccaaatg aagttgtgaa aactctactc gaagcagtaa
    25801 acagcaatgt ggctcaactt ttgatcgtgt cagacttgac catcgcagaa gggccagctc
    25861 cagaagctgc tgttagcttc gaagatgtag ccttcacagt tgaacgcgct gcaggtcaag
    25921 tatgtgaccg ttgccgtcgt atcgacccaa caacagcaga acgcagctac caggcagtca
    25981 tctgtgacca ctgtgcaagc atcgtagaag aaaactttgc ggaagcagtc gcagaaggat
    26041 ttgaagagaa ataaggttga aaagtctagg caaaattcaa tttgagaaga aaagacaact
    26101 aattttatag tctattaaac gcattgtatc acgtttttga atacctgata tgatgcgttt
    26161 tttatttatt ttaaaaattt gcgaggtatg actttttata ctcaacaaga atcaaagaga
    26221 aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg ataagattgc
    26281 taaatagtgt aatattttta caataataaa tttatatagt tatttttggt ttctgaaaag
    26341 tattatattt tatttcatat tatacaaatt tttattttat aatatcagaa aatacttttt
    26401 ttaaaagcaa atatgataca attttatttg aaaaaaataa aaaaggagat tttattatga
    26461 aattaaaaac acttgcttta attagtggta tcgtcggtct tgtgggagga attttacttc
    26521 ttattggtcc ttttgtcttg ttgggaacag cggtaaacac agttgctaca actcttaatg
    26581 gaggagctac tgcaggggct ttttcaggtg ttgccttact cttgaatgcc ttgaagattg
    26641 caaatcttgt tcttggtatc attgctattg tttactataa aggagataat cgtgtaggtg
    26701 cagctccgtc tgtactaatg attgtttttg gtggagttag tctcattcca ttcttaggat
    26761 gggttggggg gattcttgtt attatcggag gatctctatt ccttgcaaca ttgaagaaat
    26821 tcaaatcaga agaataaaag gtattttagc atgaaaagaa caaaaaagtt tatcggtata
    26881 ggagtagctc tattatctct ttttcttcta gttgcatgtg gaacataaag ttcaaaggat
    26941 acttcaacaa gtaatgatga gaagacagta gcaacatcca atagttcaaa agaaacaatc
    27001 actttcgata caccggttgt aacagacgat gtgattgaat caatacgcac ttatgcagat
    27061 tatatagatc tttataaaaa tatttttgat gattatttta ctaaagctga ggaaggtttc
    27121 aaaggcacag ctatggaaaa taatgactcg tttactaaac taaaagagtc aactcaaaaa
    27181 ttattcgatg cgcagaaaaa aaggttaaat aatgaagata gaatagaaac aactaaaaac
    27241 aatgtgattg ccaaacattg tcaaacagtc ctttcctttt tggttttgac tagctttttt
    27301 gtgaaaaatt gtgtaaaata gaatagataa acgaggggaa acctcggaaa atttaaagga
    27361 gaatccatct aatggtaaaa ttggtttttg ctcgccacgg tgagtctgaa tggaacaaag
    27421 ctaacctttt cactggttgg gctgatgttg atttgtctga aaaaggtaca caacaagcga
    27481 ttgacgctgg taaattgatc aaagaagctg gtatcaaatt tgaccaagct tacacttcag
    27541 tattgaaacg tgctatcaaa acaactaact tggctcttga agcttctgac caattgtggg
    27601 ttccagttga aaaatcatgg cgcttgaacg aacgtcacta cggtggtttg actggtaaaa
    27661 ataaagctga agctgctgaa caatttggtg atgagcaagt tcacatctgg cgtcgttcat
    27721 acgatgtatt gcctccaaat atggaccgtg atgatgagca ctcagctcac acagaccgtc
    27781 gttatgcttc acttgacgac tcagtaatcc cagatgctga aaacttgaaa gtgactttgg
    27841 aacgtgctct tccattctgg gaagataaaa tcgctccagc tcttaaagat ggtaaaaacg
    27901 tattcgtagg agctcacggt aactcaatcc gtgcccttgt aaaacacatc aaaggtttgt
    27961 cagatgacga gatcatggac gtggaaatcc ctaacttccc accattggta ttcgaattcg
    28021 acgaaaaatt gaacgtcgtt tctgaatact accttggaaa ataaaaaatt gtaagtctag
    28081 aattgatttc taggcttttt atgttagtat ggaagtatga taaggaataa aaaacaagat
    28141 tatgtactgg cctacaagca accagtttca accacttaca tgggttggga agaagaagct
    28201 ttaccgatag gcaatggttc tttaggagca aaagtatttg gccttatagg ggctgaacgg
    28261 attcaattta atgaaaaaag tctctggtct ggaggtccac ttcctgatag ttcagattat
    28321 cagggtggaa atcttcagga tcagtatgtt tttttagctg agattcggca ggctttggag
    28381 aagagagatt acaatctggc taaggaactg gctgagcagc acctaattgg gccaaaaacg
    28441 agtcaatatg ggacctatct gtcttttggg gatattcaca ttgagttcag ccagcaaggt
    28501 acgactttgt ctcaggtgac ggactatcag agacagctga atattagtaa ggcacttgtg
    28561 acgacttctt atgtctataa gggaacgcga tttgaacgtg aagcttttgc gagttttcca
    28621 gatgatctct tggttcagcg ttttactaag gaaggggcgg aaactctaga ttttactata
    28681 gaactatcct tgacctgtga tttggcttct gatggaaagt atgagcagga aaaatctgat
    28741 tacaaggagt gtaagttgga tattactgat tctcatatct tgatgaaggg aagagttaag
    28801 gataatgatc tgcggtttgc tagttatcta gcttgggaaa cggatggaga tattagagtt
    28861 tggtcagata gggttcagat atcaggagcc agttatgcca atctcttctt ggccgctaag
    28921 acggattttg cccaaaatcc tgctagcaat tatcgcaaga aactagattt agagcaacag
    28981 gtgatagact tggtggacac agctaaagaa aagggctata cccaattgaa atcaaggcat
    29041 atcgaggact accaagcctt attccagcgt gttcaattgg atttggaagc taatgttgac
    29101 gcattcacta cagatgattt gttaaaaaat tataagccac aagaagggca ggctttggag
    29161 gagctgttct tccagtatgg acggtattta ttgattagtt cgtccagaga ctgcccagat
    29221 gctctaccag ctaacctaca gggagtctgg aatgcggtcg acaatcctcc ttggaattcg
    29281 gactatcact taaatgtcaa tctgcagatg aattattggc cagcctatgt taccaatctc
    29341 ctagaggcgg tctttccggt catcaactat gtagatgatt tgcgtgtcta tggtcgtcta
    29401 gcggctgtaa agtatgcagg aatcgtctct caaaaaggtg aggaaaatgg ttggttggtt
    29461 catactcaag cgactccctt tggttggacg gcacctggtt gggattacta ttggggttgg
    29521 tcaccagctg ccaatgcgtg gatgatgcaa accgtttatg aagcctattc attttatagg
    29581 gaccaagact atctcaggga gaaaatttat cccatgttga gggaaacggt tcgtttttgg
    29641 aatgcctttt tacataagga tcagcaggcg cagcgttggg tgtcttctcc gtcttattcc
    29701 ccagaacatg ggccgatttc gattggcaat acttatgacc aatctctgat ttggcagtta
    29761 tttcatgatt ttattcaggc tgctcaggaa ttgggactgg atgaggactt gttgactgag
    29821 gttaaggaga agtctgattt actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg
    29881 gagtggtatg aggaggaaga gcagtatttt caaaatgaga aagtggaggc ccagcatcgg
    29941 cacgcttccc atctagtggg actctatcct ggcaatctct ttagctacaa gggacaagag
    30001 tatattgaag cggcacgtgc tagcctcaat gatcgtggag atggcggcac aggctggtcc
    30061 aaggctaata agatcaatct ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta
    30121 ttggcagagc agttaaaaac atccaccttg ccaaatcttt ggtgtagcca tcctcctttt
    30181 cagatagatg gtaattttgg tgctactagt ggcatggcag aaatgttact ccagtctcat
    30241 gcagcttatc tggtacctct agctgcccta cctgatgctt ggtcaacagg ttctgtttca
    30301 ggcttaatgg cacgtggaca ttttgaagtg agcatgagct gggaagataa aaaactctta
    30361 cagttgacca ttttatcaag gagtggagga gatttgcgag tttcttatcc agatattgag
    30421 aagagtgtga ttaaaatgaa tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt
    30481 atttcggtgg caacagcaga aggtgatctt gttcaatttt atttttaaga agatgttata
    30541 aggcagtaat ttgaaacttc cttttaataa ggatttaaga atataggcag tttccaacta
    30601 gttgaaaaag cgttataatg ataataggaa gtaatactca atgaaaatca aagagcacaa
    30661 actaggaagc tagccgcagg ttgctcaaaa cagtgttttg aggttgtaga tggaagctga
    30721 cgtggtttga agagagattt tcgaggagta taatttgttt gatagagggt gggtctgatg
    30781 gcttatattg agatgaaaca ctgttacaag cgttatcagg ttggggacac ggagattgtg
    30841 gccaatcgtg atgtgaattt tgagattgaa aagggggagc tggttattat ccttggtgct
    30901 tcaggtgcag gcaagtcaac agttcttaac cttcttgggg gaatggatac caatgatgaa
    30961 ggggaaatct ggattgatgg tgttaatatt gcggattata gttcccacca gcgcaccaat
    31021 taccgtagaa atgatgtggg gtttgttttt cagttttata atctagtttc taatctgaca
    31081 gctaaggaaa atgtggaact ggcttctgaa attgtgacag atgccttgaa tcctgatcag
    31141 gtcttgacag atgtaggtct ggctcatcgt ctcaataact ttccagccca gctttctgga
    31201 ggggagcaac agcgagtctc cattgcacgc gcggtagcca aaaatcctaa aattctcctt
    31261 tgtgatgaac cgactggagc cttggattat cagacgggca agcaggtttt gaaaattctc
    31321 caagacatgt ctcgtcaaaa gggagcgacg gtgatcatcg tgactcataa tggagctttg
    31381 gcgcccattg ctgatcgcgt gattcatatg cacgatgcca gtgtcaagga tgtggtgctc
    31441 aaccagcatc ctcaggatat tgacagtttg gagtactagc atgatcaagc gaaaaactta
    31501 ttggaaggac ttaattcagt ccttcacaga ctccaagggg cgttttttat ccatcttgat
    31561 cctgatgatg ttgggatctc tagccttagt aggcctcaaa gtaaccagtc ccaacatgga
    31621 ggcgacagct aatgcttatt taacaactgc tcaaaccttg gatttggcag tcatgtctaa
    31681 ctatggcttg gatcaagcag accaagaaga actaaaacag acggagggcg cagaggtcga
    31741 gtttggctat ttgacagatg tgactatgga taatgggcag gatgccattc ggctgtactc
    31801 caaaccagag cgaatttcaa cctttcagct aagaaaggga cgacttcctc agtcagacag
    31861 ggaaatcgct ttggccactc atttgcaagg ccaatacagc gtgggacagg agattagttt
    31921 taaagaaaaa gaagagggtc attcctcttt aaaagaccat acttatacca ttactggttt
    31981 tgtggattcg gctgaaatcc tctcccagcg agatatgggc tacgcaggaa gtggaagtgg
    32041 gactctgaca gcctatgggg tgattttacc tagtcaattt gatcagaaag tctacaatat
    32101 agctcgtttg aaatatcaag atttagcagg tttaaatgcc ttttcatcag cttatgaaga
    32161 aaaatccaag caacatcagg aagaccttga acaaacttta tcagataatg gcaaggtacg
    32221 tctgcaactt ttgaaaaaag aaggacaaga gtctctagac aaggggcaag agactcttga
    32281 caaggctcag actaatttgc aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat
    32341 acaggctcaa gaaagtcaac tagccttgtt tcctcaagct cagagagagc aggctagtgc
    32401 tcaacttacc caagccaagc aggaactggg caaggaagag gacaaactaa agcaagctga
    32461 acaaaatcta gcccaagaaa aggaaaaatt agaaaaacat cagcaagtct tggatgattt
    32521 ggcggagcca aggtatcagg tttataatcg tcagaccatg ccaggtggtc agggctatct
    32581 tatgtatagc aatgcttcat ccagtattcg agcagtgggc aatatctttc ctgtggtact
    32641 ttatgccgta gcagccatgg tgacctttac gaccatgact cgctttgtag acgaagagcg
    32701 aactcatgca gggattttta aggccttggg ttatcgtagt aaggatatta tcgccaagtt
    32761 tctcctttat ggactagtag ctgggactgt cggaacggct ctaggtagta tacttggtca
    32821 ttatttgcta gccagtgtaa tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac
    32881 ccagattcag ttctattgga cctatagctt actagctctt gtcttgagct ggttggcgag
    32941 tgtgttacca gcctatctgg tggcttggag ggaacttcat gacgaagcag cccagcttct
    33001 acttcctaaa cctcctgtca aaggagctaa aatcttattg gagcgtatcg gttttatctg
    33061 gcgtcgtctc agttttactc ataaggtaac agcccgcaac atctttcgtt ataagcagag
    33121 aatgttgatg acaatctttg gtgtggcagg ttctgtagct ctgctctttg caggtttggg
    33181 aatccaatct tctgtagcag gagttccgtc taaacagttt caacaaatcc aacagtatca
    33241 gatgcttgtc tctgaaaatc ctagtgcgac caatcaggac aaggtagagc tagcagaagt
    33301 gttgaaaggg caggagatac tagcctacca gaaaatctat tctaaaacgc tagacaagga
    33361 tttcaagggc agggctggtc ttcaaaacat tactcttatg atgatagaga aggaagattt
    33421 gactcccttt atccatcttc aacatcatca gcaggagctg acattaaaag atggcatcgt
    33481 tattacagct aaactcgccc agctggcagg tgtcaaggtt gggcagactt tagaaattga
    33541 aggtaaggaa ctaaaggtcg ctgctattac tgagaactac gttggtcact ttatttatat
    33601 gagtcaggct agctatgagc aactttacgg acagctaccc caagccaaca cttatctggt
    33661 ctcattaagg gataccagtg caactagtat cgaaagtcag gcgggcttgc ttatgaatca
    33721 atctgcggtg tccagtgttg tccaaaatgc ttcagccatt cgactcttcg actctatcgc
    33781 tagctcactc aatcagacca tgaccatctt ggtcatcgta tcggttctat tagctattgt
    33841 catcctttac aatctgacca atatcaacgt agctgagaga atccgtgaac tctccactat
    33901 caaggttctc ggttttcata ataatgaagt caccctctac atttaccgtg agacgattgt
    33961 gctgtccctt gtgggaatcg tacttggtct ggtagctggt ttctatttac accaattttt
    34021 gattcaaatg atttcgcctg cgactattct cttttatccg caggtaggct gggaagtcta
    34081 tgtaatccca gtggcagcag taagcatcat tttgaccttg cttggtttct tcgtcaatta
    34141 ttatctgaga aaggttgaca tgttagaagc cctgaaatct gtagagtaag gtagttattt
    34201 ttagctgatt gaacttctat ttactaatat tcaaaaatcc tccgtttcaa agagcaggga
    34261 actctttgtg acagaggatt ttttctatag ggctttagca gctgcaattg cggcttcgaa
    34321 gtttggctca gaattgatat tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc
    34381 gaggacaaag actgcgcgtg ctaataggtg ccattcgttg atcaagaggg cataatcgcg
    34441 tccgaaagaa tggtcaaagt agtctgaaag cataatggca ttgtcaaggc cttcagcacc
    34501 gcaccaacgt ttttgagcaa aaggtaggtc cattgaaaca gtcaatacga ccgtgttgtc
    34561 cagtccagcc aattcttcat taaaacgacg tgtttgagtt gagcagatgc ctgtatcgat
    34621 agaaggaacg acactcaaga cttttttctt gccatcaaaa tcagccagag attttttaga
    34681 aagatctgtt gtagtaagag aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc
    34741 tgtaaagctc acaggatttc cgagaaaagt taccatagga tactccaatc ttttttcttc
    34801 cattgtatct gaaacagtca gaattttcca atgatttgac cggaaatgtg tgcatagaaa
    34861 aaacgccagc tcacatgaga atgacgtttt tcagaggctt attttgccaa tccttcagca
    34921 atcttgtcaa ggttgtattt catcatgctg tagtagctgt cgccttcttt accttgttct
    34981 gcgatagagt cagtaaagat ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt
    35041 ttcattggac ggtcatccac acttgattct acaaagagtg atggaacttt tgtttggcga
    35101 agtttttcaa ccaaggtctt gatttgttca ggagttcctt cttcttcagt attgatttcc
    35161 cagatgtagg cacttgggac accataggct ttagagaagt atttgaatgc tccttcgctg
    35221 gttacaatga gtttcttttc agcagggatc ttattaaatt tatccttact ttctttatca
    35281 agtttgtcta acttatcagt atattctttg agattttttt catagaattc tttattgtta
    35341 gggtctttgg cgctcaattg tttggcgata tttttagcaa aaataatacc gttttcaagg
    35401 ttaagccaag cgtgtgggtc ttcttttcct ttttcatttt gaccttcaag gtagataaca
    35461 tcaacgccgt cgctgactgc gaagtagtct ttgttttcag ttttcttggc attttctacc
    35521 aattttgtaa accaagcatt gccacctgtt tcaaggttga taccgttata gaaaatcaaa
    35581 tcagcctcag aagttttctt aacgtcttca ggaagtggtt cgtattcgtg tgggtcttgc
    35641 ccaatcggaa cgatactatg aaggtcaatt ttgtcaccag caatattttt agtaatatca
    35701 gcgatgattg agtttgtagc aacaactttt agtttttgac cagaagttgt atcttttttt
    35761 ccgctagcac atgctacaag aatgattgca gaaagaaaga gaacgagtaa tgtacctaat
    35821 tttttcatta gatcctccaa tttattaggg ctttgcccct tattttaaca aatgtttatt
    35881 tttcagtttc aaatatcgtt gtttgggagc gataaagaag ctaatgagaa agaaactagc
    35941 agctgtaagc acgatactag aacctgccgc aacattaaaa ctatagccaa taaagagtcc
    36001 caaaactgaa gcagtagctc cgaaggttga ggaaaggaaa atcatgcttt tcagactatt
    36061 agcatacaga taagcagttg cagctggggt aatcagcatg gctacaatca ggatagttcc
    36121 gacactttgc atggctgtca cagacacgag agtcaggagt accatgagaa ggtagtgata
    36181 gaaattgaca ggcattccca tggctttagc caagagttca tcaaaggaag ttatcaagag
    36241 ttgcttgaag aaaatccaga ttaacaagag gatggctgcc cccacaccca tagtaataaa
    36301 catatccgta tcttggacgg ccagaatatt accaaaaagg atatggaaaa ggtcagttga
    36361 acttttagcg acaccaatca agatgatacc gagggctaag aaagaagaaa aggtaatgcc
    36421 gatggcggta tcgcttttga taatcgagtt tcctttgatg taggtaatga tgatggcagc
    36481 tagcaatcca aagacaatgg ctccgataaa gaagtcaagg cccaagatga aggagagggc
    36541 tacacctggt aagacagcat gtgaaatggc atctcccatg agtgacatcc cgcgtagaat
    36601 aatgaaacat cccacggctc cagctacaat cccgacgaca atagctgtta tcaaggcatt
    36661 ttgtaggaaa tggaattttt gcaatccatc gataaattct gcaatcatag gtcacctcca
    36721 ttgaaaaaga gttgattacc gtaagcttct tttagattgg tttcggtaaa agtttctttt
    36781 gttggaccaa aggcaatcac ttctcgattg acaagtaaga cttgatcgaa gtagtgggga
    36841 atcttgctga ggtcgtggtg aacgatgaga accgtcttcc cagctttttt caaatctctc
    36901 agcgtattca tgatgatttc ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag
    36961 aggatatagt cggcttcctg caccaaacat ctggcaatca agacccgctg gaattgacct
    37021 ccagacagtt gactaatttg acgttcagcg tagtcagcta ggccgacgat ttcaagggcc
    37081 tcttgcactt tcttccaatg tttagccttt aaacttcgaa agagaggaat agagggaaat
    37141 agtcctaacg agacgcattc cttgaccttg atgggaaagt tgtagtcgat attgattttt
    37201 tgttcgacat aggcaattcg gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc
    37261 tgaccttgat gtgggataat tcccagcata ccttttaata gtgttgattt cccagcgccg
    37321 tttggaccaa tgatgccggt aattgttggt ccatggagca ctagtgaaat atccttaagt
    37381 gccaacgttt ctttgtagga gacactgagg ttttcgatac gtatcataaa cttgtattcc
    37441 tcctgtctct taatatacat taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta
    37501 aaataataac tgaaaaatag attctaaaga taactttcag gataaatttc taaattataa
    37561 aacgcatagt atcaagtgta aaaaacttgg aattatgcgt tttatcatgg aaagattttt
    37621 tataatagct aaaaaataat agttaaatgg ttattaattg cattccctag tgatttttgt
    37681 taagataaat gcaaatacaa atgaaagcga gaacaagatg acacgttatc aagatgattt
    37741 ttatgatgct atcaatggag aatggcaaca gacagctgaa atcccagcag ataagtctca
    37801 aacaggaggt tttgttgatt tagaccagga aattgaagac ctgatgctgg cgacaacaga
    37861 caagtggtta gcaggtgaag aagtgcctga ggatgctatc ttggaaaact ttgtcaaata
    37921 ccaccgccta gttcgtgatt ttgacaagag agaagctgac ggtatcacac ctgtcttacc
    37981 actccttaaa gaattccaag aattggaaac ttttgcggat tttacagcta aactagcaga
    38041 gtttgagctt gcaggaaaac caaacttcct tccttttggt gtatcgccag actttatgga
    38101 tgctagaatc aatgttctat gggctagcgc tccaagcaca atcttgccag atacgaccta
    38161 ctatgcagaa gaacatcctc agcgcgaaga gctcttgact ctttggaaag aaagcagcgc
    38221 aaatctcctc aaggcttatg atttctctga tgaagaaatt gaagacttgc tagaaaaaag
    38281 acttgaattg gaccgccgag ttgcggcagt ggtgctctct aatgaagaaa gttcagaata
    38341 tgctaaactc tatcatccat attcttacga agatttcaag aaattcgcgc ctgccctacc
    38401 tttggatgac ttcttcaaag cagttattgg gcaattacca gacaaggtta ttgtagacga
    38461 ggaacgtttc tggcaagcag cagagcaatt ttacagtgag gaagcctggt ctctccttaa
    38521 agcaaccttg attttgagtg ttgtcaatct ttcaaccagc tatttaacag aggatatccg
    38581 tgttttgtct ggtgcctaca gccgtgccct ttctggagtt ccagaggcaa aagataaggt
    38641 caaagcagct tatcatctag cacaggaacc tttcaagcaa gccctggggc tttggtacgc
    38701 ccgtgagaag ttctctccag aagccaaggc ggatgtggag aaaaaagtgg caaccatgat
    38761 tgatgtctat aaggagcgtc tgcttaagaa tgactggctc actccagaaa cctgtaaaca
    38821 ggctatcgtg aagctcaatg tgatcaaacc ttatattggc tatccagaag aattgcctgc
    38881 acgttacaag gataaggtag tgaatgaaac tgccagtctt tttgagaatg ctctagcctt
    38941 tgcgcgtgtg gaaatcaagc acagttggag taagtggaac cagcctgtag actataagga
    39001 atggggcatg cctgctcata tggtcaatgc ctactacaat cctcagaaga acctgattgt
    39061 ctttccagcg gccattttac aggcgccttt ctatgacttg catcagtcat cttctgctaa
    39121 ctacggtggt attggggcag tgattgccca tgaaatttcc cacgcctttg atactaacgg
    39181 ggcttccttt gacgaaaatg gtagcctcaa ggattggtgg acagagagcg actatgctgc
    39241 cttcaaggag aaaacacaaa aagtcattga ccaatttgat ggacaggatt cttatggagc
    39301 aaccattaac ggtaaattga ctgtatcaga aaacgtggct gacttgggag gaatcgcagc
    39361 agcgcttgaa gcagctaaga gagaagcaga cttctcagca gaagagttct tctacaactt
    39421 cggtcgcatc tggcgcatga aaggtcgacc agaatttatg aaacttttgg ctagcgtcga
    39481 tgtgcacgca ccagccaaac tccgtgtcaa tgtgcaagta ccaaacttcg acgatttctt
    39541 tacaacctat gatgtcaaag aaggagacgg aatgtggcgt tcaccagagg agcgcgtgat
    39601 tatttggtaa tacaaaaaat ctagtcatca gaaaaaaggc atccaatcac gtgtgaaaac
    39661 cttgatagga tgccttttgt aatagaaaga tttgctggat agtttactta aatttcgatt
    39721 gtcatcatct tgctagaaaa agggattgaa ggccttttcg tgagcgatag tagtagctgg
    39781 accatgtcct ggatagacat cgtagtttgg tagggtgaag agttgggtct ggatactatg
    39841 aaggagttgc tccatgctac cagtcggaag gtcggtccgt ccgatagttt cgcggaatag
    39901 agcatctccc gtcaagacta ggtgagcatc aggaaagact agggaaacac caccgataga
    39961 gtgccctggg gtcggtagaa ccttaaaacg aaattcctct agttggtatt cttcgtgaaa
    40021 gacaaaggtg tgttctgcag gttttgtgac cacatctgcc atatcatcgt ggcgagggag
    40081 accggagaga ttatcgacag gagtgtagag ccagctggct tcgctctctg cgatatagac
    40141 aggaggattg ccaaacgtct cgcgaaccaa gtccagactc atgatatggt cataatgggc
    40201 gtgggtcaag agaatagcac agatcggttt gttgatcttc tcgattgtct gacgaatggc
    40261 ttcccaatga ctaccaggat cgacgacgat gaggtgcttt tcgccttcta gataataggt
    40321 attttcatag gcaacaggat tcacggtttt atggattttc atactagctc caatctcaaa
    40381 gaatgtacta atactcttcg aaaatctctt caaactgcgt caactttatc tgcaacctca
    40441 aagcagtgct ttgaacagcc tgcggctagc tttctagttt gctctttgat tttcattgag
    40501 tataaattaa gtatagcaca gttagggaga ataggtaagg atttaaaatg aacttaaaaa
    40561 ccagcatgac tagatgaaga caggctggtt atcaatttat caatattgga aaggtgtcaa
    40621 ttgcccttca taggttgcat aaactccgtc attagcttgt ttgatagacg tgatgtttag
    40681 agtgctaccg tagttggctt ctcgtttgtc gctatattca ctataagtta tcctactggg
    40741 caggttctgg tcgttagcat agtattgaac gactgttttt tatagctttg ctggctgaat
    40801 aggaacaggc agcaaactcc taacattagg agagcaaaga tagaaatagc agtttttttc
    40861 ataggtattc tccttataaa ctaaaggata gaagaaagta tcttgaggat ttttatactc
    40921 ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttgccg tatatatgtg actgactttg
    40981 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt
    41041 tgctctttga ttttcattga gtattaattc caaaatccag tcaaggtacc agtgtatgtg
    41101 atacgagttc caccgtttat ctttcgtatc ttcaatggaa ttggggaaat cagaaagtct
    41161 ttgggttaca atatggtttc cgttcttcta tctctccttc tatcacctaa gtttaaaatc
    41221 taacttcgta gtatattatg ggccaataat tcagaattat caagcaattt tgaattattt
    41281 ttttcttatt ctgttccaat ctagttttca tattcttaaa aaagtgataa aatggtagga
    41341 agaattggag agtagagatg ccgaaagaag tgaatttaac aggcgaagaa gttgtcgctt
    41401 taaccaaaga atatttaacg gaagaggatg ttcattttgt ccataaggcc ttggtctatg
    41461 ctgttgaatg ccacagtggt caatatcgca aatcaggcga gccttatatc attcacccta
    41521 tccaagtggc aggtatttta gctaagctaa agctggatgc tgtaacagta gcttgtggat
    41581 tcttgcatga tgtggtggaa gatacagatg cgaccttgga cgatttggaa agagagtttg
    41641 gtcctgatgt gcggatgatt gttgacggag ttaccaagct tggcaaggtc gagtacaaat
    41701 cgatcgagga gcaattagcg gaaaatcatc gcaagatgct catggccatg tctgaggaca
    41761 tccgcgttat tttggtcaaa ctgtctgacc gcttgcacaa tatgcggacc ctgaaacatc
    41821 ttcgaaaaga caagcaggag cgtatttcca aagaaaccat ggaaatctat gccccgcttg
    41881 cccatcgttt ggggatttcc agtgtcaaat gggaattaga agacttgtct ttccgttatc
    41941 tcaatccaac ggagttttac aagattaccc atatgatgaa ggaaaagcgc agggagcgtg
    42001 aggccttggt ggatgaggta gtcacaaaat tagaggagta tacgacagaa cgtcacttga
    42061 aagggaagat ttatggtcgt cccaagcata tttactcaat tttccgcaaa atgcaggaca
    42121 agagaaaacg gtttgaggaa atctatgatc tgattgctat tcgttgtatt ttagataccc
    42181 aaagtgatgt ttatgccatg cttggttacg tgcatgaatt ttggaaaccg atgccaggtc
    42241 gcttcaaaga ctatatcgcc aaccgcaagg ccaatggtta tcagtctatc catacgactg
    42301 tttatggacc aaaagggccg attgaattcc agattcgaac caaggaaatg cacgaggtgg
    42361 ctgagtacgg ggttgcggct cactgggctt ataagaaagg tataaagggg caagttaaca
    42421 gcaaggaatc agctattgga atgaactgga tcaaggagat gatggagctc caagaccagg
    42481 ctgatgatgc taaggaattt gtggactctg ttaaggaaaa ctatttggct gaggagattt
    42541 acgtttttac cccagatgga gctgtccgtt cccttcccaa agattcagga ccgattgatt
    42601 ttgcctacga aatccatacc aaggtcggtg aaaaagcaac tggtgccaag gtcaatggcc
    42661 gcatggttcc actgacaacc aagttaaaga caggggatca ggttgaaatt atcgccaacc
    42721 cgaactcctt tggacctagc cgtgactggc tcaatatggt caagactagc aaggcgcgca
    42781 ataagattcg ccagttcttt aaaaaccaag ataaggaatt gtctgtcaac aagggtcgtg
    42841 agatgctgat ggctcagttc caagaaaatg gctatgtggc aaataaattt atggacaagc
    42901 gccacatgga tcaagttctg caaaagacca gttacaagac agaagactcc ctctttgcgg
    42961 ccattggttt tggggaaatc ggtgcgatta ccgtctttaa ccgtctgact gaaaaggaac
    43021 gccgtgagga agagcgtgcc aaggccaaag ctgaggcaga ggagcttgtc aaaggtggcg
    43081 aggtcaaggt tgaaaataaa gaaaccctca aggtcaagca tgagggggga gtggttattg
    43141 aaggtgcttc tggtctccta gtgcggattg ctaagtgttg taaccccgtg cctggtgacg
    43201 atattgttgg ctacattacc aagggtcgtg gtgtggctat tcaccgtgtg gactgtatga
    43261 acctgcgtgc ccaagaaaac tacgagcaac gtctccttga tgtggaatgg gaagaccagt
    43321 actctagctc aaataaggag tatatggccc atatcgatat ctacggtctc aaccgtacag
    43381 gactgttgaa cgatgtactg caagttcttt caaatacaac caagaatatt tcaacggtca
    43441 atgcccaacc aaccaaggat atgaagtttg ctaatatcca tgtgtccttc ggtattgcca
    43501 acctctctac actgaccacg gttgtcgata aaattaagag tgtgccagaa gtttactctg
    43561 tcaaacggac caacggctag ttgtcctagc tcttactaga aaggctatta tgaaaatcat
    43621 tatccaacgg gttaaaaaag cccaagtgag tatagaaggc cagattcagg gaaaaatcaa
    43681 tcagggattt ttattgctgg ttggtgttgg accagaggac caagaggaag atttggacta
    43741 tgctgtgaga aaactggtca atatgcggat tttttcagac gcagaaggca agatgaacct
    43801 gtctgtcaaa gatattgaag gagaaatcct ctctatttct cagtttaccc tctttgcgga
    43861 tactaagaaa ggcaatcgtc cagcctttac aggggcagct aaacctgata tggcatcaga
    43921 cttctatgat gctttcaatc aaaaattagc gcaagaagtg cccgttcaga caggcatctt
    43981 tggagcagat atgcaggttg agctggttaa taacggacct gttaccatta tcctagatac
    44041 taaaaagaga tgagaaagac caagcccagt cggcttggtc tttctcatct atcataaaat
    44101 actccaaaaa gaaatcggtt cttgatatgc ttgggggaag tctcttttca ggctttggca
    44161 gatgcgatag gaagggatga gatgtcctag gatgaggaga gttccctgaa ggaaaagtgg
    44221 aatatcactt aaagacacca aggagagaat catcaggcta tcccatagga gaatttgtaa
    44281 agcaaaacgc cagaatctcg gtctaatctg ggaatagagt taactaaagt ggtcacaaag
    44341 ttggtttgaa agataggtca atagcacagg atgaaagaaa atgagccaac cgctataaat
    44401 caaaatccag tcccaagtaa gctccctttt aaatgtcaaa aatgccagca tgattccatc
    44461 aatgacaagg agttgaatgg ttttgatgaa tatgattttt ttcatgctaa aacctccttt
    44521 tccttagaga cactcccata aagagatgtg tttgtcgtaa aagtctggat agttttctcc
    44581 taggtagtca gctgtcatat aataaaaagt agaatggcga gcagtgatga ttggcataag
    44641 agatgaaaaa cgctgagaac taatgaaggc taagagaaca aaaaatagaa aatcaatggt
    44701 gagaatccct aaatagtaga agcgaatctt tttattgatt tgaggataaa tctcagcgaa
    44761 ttgatgtttg agtcggacga ccaagagaaa tagcaggagt ccttgatcaa ggaagaaaat
    44821 taaaccagag agcaagagcc actcaaaaga tgtctcgagt ctagtgataa aaaatgcaaa
    44881 tagtagcaaa tcaataactg caattgctat aaaatggatt ctatagagtt ttttcatgac
    44941 aagaccttcc tcttttatct aacttcattc tactccaaaa gaatgggagt tacaactaaa
    45001 atgataaaaa tagcagaggg gagattctct taagttggct agtattcttt atttgagttt
    45061 ccttctatta tctaacttct tcatcattcc tgacaaataa agctccgatt gcattgagga
    45121 tataaaagat gtatttaccg atattggcga agtttccttg aataccagct tttgtcagct
    45181 gaacgaaatt gtaaatcaac caaaagcccc actgagttgt tagtttcaat gcattcaaag
    45241 cattggcaat gagggacagt gcaaaggcaa tagttgttac gtaggcaagg agattcatct
    45301 tgcccccata tccgatatag ttggtcacaa aggcaaagag gaaggcgatg atggaaatga
    45361 tgatgggcgc caattttacc tgtttttggc tcatttggtt gggtctgcct tcttgcgaag
    45421 ctttccattt ctttatagca aaggtataaa tgaggaaggt gacgggatag gtaatgatgg
    45481 ccgccttatt tccaaggata taatcaatag caccggacaa aatggtatta acaataccaa
    45541 agtaatttcc ccatttgctt aatttccccg tgaaacgagt ggacaacatg gaaatcccaa
    45601 cgttagttac ggaaatcaat ccaaagggta caagagctgt ccatagtccc cagtctacaa
    45661 atttatggag gcgtgagttg agataaccag atgcaatcgc aatcccaacg accaaagcaa
    45721 ccccgaagag gtcaaactat ttagatgtag caaaaatttt tagtgatttt ttcataggtt
    45781 aaactacctt tctttttttc aaatattctc ccattttttt caaatattct cacaccaaat
    45841 gaaagtaaaa taaaatgata gaaataaaac cctgaaaata aaactttcag ggttggtagg
    45901 ggacttgaga aattagttga ttttctcgac atagagttgt tttgcaatgt ccatattcac
    45961 ttgtaaatcc tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt
    46021 gacttggagc tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa
    46081 actatcgtgc acccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag
    46141 gttattgatt tcaacgagga gttctccctt ggcaggaata gttcctccgt gggggcaggt
    46201 tttagggaaa cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc
    46261 caagacctca gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa
    46321 aacttcaatc aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt
    46381 cagtagatag ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat
    46441 catttcagtt acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat
    46501 cttatgcagg tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt
    46561 cattcgtttc ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct
    46621 agctgtgact ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg
    46681 aaaatagctc ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca
    46741 gatgctcggc agataggagt ggatgaatac tggcttttgg gagatattct catgccaggg
    46801 acagggcgta gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg
    46861 ggaaactggg aagacagtct ttggcatggt gtccgtaagg aattggatag tactcgcccc
    46921 agtcaacgct atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa
    46981 attgaagtgc tccacaatca acctcttcaa attcatcgtc agtttgggga tttgacggtg
    47041 ggaattagtc atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa
    47101 caagaggatt ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacat
    47161 attcaccagc agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg
    47221 attggccaac ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg
    47281 attttggagt ttgatgacaa gggcctggta gatatggact tccgacgggt agactacgat
    47341 gtggcagctg aattgcagct ggctaaagac ctgagacttc cctattttga ggtttactat
    47401 gaaagtctgg tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct
    47461 cagaaagagg gctgcgaccg ggagttagac gactggttga aaagtggtaa cgattgacat
    47521 tacaactaaa aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa
    47581 aaggagaaga ggatgcaaat tccaagtaga tttaccattg cgactcatat gctgataatc
    47641 attgccctcg aggggaagga aagcaaggtg accagtgatt ttctggctgc tagtgtcggg
    47701 gtcaatcctg tcattatcag aaagatcttg tcccagttga agaaggcaga gctgatttca
    47761 gtagcgcgtg gaacgggcgg aacagagatt gtcaaggacc ttaaggatat tagtctttta
    47821 gatgtttatc aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac
    47881 aatccgaatc caaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg
    47941 gagagaattc agttgactat ggaggcagaa cttggtcaaa ccagtctaga aaaagtcgtg
    48001 gccgatgcag agagtcagat gaaggattaa gagggataaa tgccctcttt tttctttgga
    48061 taattatgat aaaatgtagc tattaaagga gtaagaaatg tatctcgtta taggaattgt
    48121 attagccttt atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt
    48181 tttattatcc ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata
    48241 cgagaatgtt cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt
    48301 tctaagtggc atctttttaa tctataatgg ggtcattttg ttgaagcgag agggacgttc
    48361 caagccccat tatctctcaa tgctctttga tttttattga ctattagatt ctatttaaaa
    48421 agacttagaa tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt
    48481 ttcaagagta ttatctattt ttccatgcct ggtaacgagt atcaatcaat aactgggtaa
    48541 ggcgacccaa ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat
    48601 gaatgtattc aagcgccttt aaggaagcca agtcattgat agagctaata ccagcctcaa
    48661 gaatagtgcc aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca
    48721 cccattcttt aaaggttgtg tctacttgct ggctatcact gttggtctta tccagttgga
    48781 cgaagtgctt gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg
    48841 cagtactctg aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac
    48901 cttgtggaat gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca
    48961 attcttgatg gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac
    49021 tttgctcaat ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcta
    49081 gaataacctt ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct
    49141 tttgagcagg aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac
    49201 tgtcatctgt cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag
    49261 ccgcaaattg cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat
    49321 ttttgaagcg cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa
    49381 gcatggtggg atctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg
    49441 agaccagatt atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat
    49501 tcaagggaag gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg
    49561 ccataagagc tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc
    49621 attgcctgtt tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctggc
    49681 atggaaaaat ctgttataat aatggaaaag gagaagcgca tgcacaagat tttattagtg
    49741 gaagatgatc aggtcattcg tcaacaggtc gggaaaatgc tctctgaatg gggatttgaa
    49801 gtggtcctgg tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat
    49861 ctggtcctca tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc
    49921 cgcaagattt ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt
    49981 gtcatggcaa tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt
    50041 cttttagcta aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt
    50101 ttgctggaat atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg
    50161 caagtcttga atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca
    50221 ggcaacatcg tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt
    50281 gatgataata ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga
    50341 ttggtaggat ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg
    50401 gaaacaattt tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc
    50461 tttggcattt ctggtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct
    50521 ctactttttc ttcttgtgtt gctttgtaac catcttattt ttcacttggg atatattggt
    50581 ggaaacgcag gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt
    50641 ggaaatagct ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc
    50701 aaaagcagaa agaaaactga cggatttgct ggattactat accttgtggg tccatcagat
    50761 aaagaccccc attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa
    50821 gcagcaacta gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta
    50881 cctgcgttta gaaagtttcc atgatgattt ggtcttaaag caggttcaaa ttgaggactt
    50941 ggtcaaggaa ataattcgta aatatgctct tgtctttatt caaaaaggct taaatgtcaa
    51001 tctacatgac cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga
    51061 gcaaatcatc tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga
    51121 tgaccaagag ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg
    51181 agtatttgaa cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact
    51241 tggcctttat ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc
    51301 tgaggtcgga aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga
    51361 gtaaaaatag atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct
    51421 caacgcgtga tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga
    51481 cagtttgtgt ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt
    51541 tgtctccaac aattaattgg taaggaatct tgctggtttg tgaagcacga atcttgaact
    51601 gcattttttc attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg
    51661 ccacttccca agcgtagtcc acgtgttttt cgttagatac tgggatgagg gttacttggt
    51721 gtggtgccag ccatgttggg aaggccccct tgtagttctc aatcaagata gctgtgaagc
    51781 gttccatagt tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag
    51841 ctccgatgta tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa
    51901 gggtttcttc ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg
    51961 ctgcttcacc ttcggcttca aagtagttca cgcccatttc atcaagagct gcacgaagca
    52021 tggtttgggc attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt
    52081 cacgaagaga gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa
    52141 tcaactgaag ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac
    52201 cgtcgttgag tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt
    52261 aacggtgcat cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat
    52321 ggtgtttgaa aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc
    52381 cgtcacccat gtccatggtt gggaacatgt cttcttggta atgatcccag tgaccagaag
    52441 tcttgtaaag ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca
    52501 actctttgtt tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggcaacc
    52561 agaatggcaa accttgtccc acttcttgtg aaattataaa gaggtcaagc tctttaccaa
    52621 gtttacggtg gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt
    52681 tcttgtcaaa ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac
    52741 gccagtacgc accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa
    52801 cgtgaggtcc acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt
    52861 cgtcttctga gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac
    52921 gtgcctcgtc tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt
    52981 gcatttcttc ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag
    53041 tatcgtagta gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa
    53101 gacgacgagc tgcttgggcg aacaagtgag ctgctgagtg acgcaagatt ggaagggcat
    53161 cttcgtgatc aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt
    53221 cgatgagttt gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag
    53281 attgggcaat ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga
    53341 aagtaatgtt aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt
    53401 ttttatcagc agactacttc caagtcctaa cgttcaattg cttttcttta tcagagagga
    53461 agttttccat ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc
    53521 agatattttc tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt
    53581 gctttgtcat caccagtcgt tggaaatttc caatatcatt agataaagcc aagaggtctt
    53641 cttctaccgt ccacttggaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga
    53701 ttgcccaact gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat
    53761 gcgacatcct cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga
    53821 gagggacacc tctgattggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca
    53881 agagtagtat cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa
    53941 agggactaag tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga
    54001 ttttgtgaaa gttttttgtt tttcatattt tgtagaatat gcttgatgct aataccagaa
    54061 tccatgccca ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca
    54121 aaggttatga tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa
    54181 cggaaacggt agctatagag taacgataca atcaagatta ccagaggtgt aaagaagaga
    54241 agattgttta tatagtgtaa gggggtcaga aacaactagc aagaacaact cataaagtgg
    54301 ccaataaaag aataatatga ccagatagta ggggagatgg gaatagaatc tacgcatgat
    54361 aatcacctcg ttttaaaaaa acagacaact tagatctctt gctatgatta ttatagcatg
    54421 tttaaaacaa gaaagtaaat ttgttgacaa agaagatttt tcttttcact agaatcatgg
    54481 ttagttttct tggtagaaat attttgataa taattaagca agactattga cattgattat
    54541 taagagtgtc acaattgttg taactaaaac aattacaaca agagaggtat aaaaaatgaa
    54601 actagcagtt attgcagcaa atggacaagc ggggaaggca attgttgaag aagcagtcaa
    54661 acgaggacat gaagtaacgg ctattgttcg ttctgaaaac aaaagtcaag ctgagtctat
    54721 tattaaaaaa gatttatttg agttgacaaa agatgatctt actggatttg atgctgttat
    54781 ttcagcgttt ggtgcttata caccagatac gctaccgctc cacagcaaat caatcgaact
    54841 atttaatcag cttcttgctg gaacacagac acgttttcta gttgtagggg gatcaggaag
    54901 cttttatata gatgaaacaa aaacgacacg acttttagat acgtctgatt ttcctgaaga
    54961 atttaagcca ctagcaaaag ctcaagcgga tgaattggat cttcttcgta caaaaaataa
    55021 tctcaactgg acttttgtca gtcctgctgt agattttatt cccgatggtg aaaaaacagg
    55081 aaactacatt ctagcaggag aaatttttac tactaatgaa aaaggaataa gccagattag
    55141 ttatgcagat tatgctattg gattggtaga tgaacttgaa aaaggtcatc atataaaaga
    55201 acgtatctct ttacttgaaa aataataact atgagagtat taatgtttga cagaaaattt
    55261 aaatcttggt aaaataggga ttgtcgtaaa gacaaataac ttcttcttgg ttacaggcat
    55321 gccaacctgt cactcggatg aagccaaata aaaaggagaa acatcatggc aatctcaaaa
    55381 gagaaaaaaa atgaaatcat cgcacaatat gcacgtcacg aaggtgatac aggttcagta
    55441 gaggttcaag ttgctgtcct tacttgggaa atcaaccacc ttaatgaaca catcaaacaa
    55501 cacaaaaaag accacgctac ttaccgtgga ttgatgaaaa aaatcggtcg ccgtcgtaac
    55561 ttgcttgcat acttgcgtaa aaacgacgtt aaccgttacc gtgagttgat caactctcta
    55621 ggacttcgtc gctaattcaa gatacaaagg ctgtcaaaag cacaaagcaa aaataggaaa
    55681 attgacgaag aaacttcagt ttctaggaga ttttatcttt tttgccaagt gcttaggccg
    55741 tgttcaattg agcatatctt gataatgaag ctactctaaa ttgggtagtt tttttgcgtt
    55801 gtcaccttac ctcgatatac tcaagtataa tcttcggtta cggttcctag cactgtaagg
    55861 taaaataaac cagcttttct cccttcgggg agattttttt ttgtttcact gaaagtttcg
    55921 tacgatcttc gcctcgtcgc ctagtctata aacgatttat ccagcaagaa tcatgatgct
    55981 aagggcgtca aaaatccgta tgaaaatagg gaaatggcac agtgttcgat gaacgcaagg
    56041 agtttcatct ttttcactag gattttagtc cgggctcaaa tcagctctct gacttcagag
    56101 ggctttttta ttgaggtttt atcggtaaca attttggaga ctacaaaaac ctcaaatggt
    56161 atcagctaat tacaccataa aggtgcgcag ttactcggct tttcaagccg agtagctgta
    56221 tgcaagcccc ctagaagagc ccactcttta caaagtaaag tatagtatgt tatactttac
    56281 atggaagtag tcactgaatt ccagttagaa attactttgt aactacgttt tgaggaggag
    56341 taaaatgctt tcctacgttc gacattaccc actagcgata gctaaattaa tgtgtctgtg
    56401 ctctcctaaa atctgctgat ttattactga ctaatacagg aggttttttt atgggacaga
    56461 caatcatatc tgctattggt gtttatattt ccaccagtat cgattattta attattttaa
    56521 ttattttatt tgcacaacta tcacagaata aacagaaatg gcatatttat gcggggcaat
    56581 atctaggcac aggcttactt gtaggggcga gtttagttgc tgcttatgtc gttaatttcg
    56641 tgcctgaaga atggatggtt ggattgcttg gtttaatccc tatctattta gggattcgct
    56701 ttgcaattct tggagaagat gcggaagaag aagaggaaga aattattgaa agattggaac
    56761 aaagcaaggc aaatcaactg ttttggacag ttacattgct gacaattgcg tctggcggag
    56821 ataatttagg tatctatata ccttattttg cttcgttaga ttggtcacag accctcgtgg
    56881 ccttgcttgt gtttgtaatc ggcataatta tcttttgcga gattagtcgg gtgttatcct
    56941 ctattccgtt aatattcgag acaattgaaa aatacgagcg aatcattgtg cccttagtat
    57001 tcattctact tggactatac atcatgtatg aaaatggcac gatagagact tttctgatcg
    57061 tgtagatttt tttgtttcac taggatttta gcccgagctc aaatcagctc tctgattttc
    57121 agagggcttt ttcattgagt ataaatggac aatcttaaag ttactctatt gtagagtggc
    57181 ttttgatttg attaggagat tcttataaat atagtaaaat gaaacaaaaa caggacaaat
    57241 cgatcgtgac agtcaaatcg atttctaaaa atgttttaag aagtagaggt gtactattct
    57301 agtttcaatt tgatatataa atgaaaacct tagctgtttg gccaaggttc atttcttcta
    57361 tgcaagttct tctcttttct tatctgggtt ccagatgaag cttgcgataa agctaaagat
    57421 gatggttagg atagcgagga taatagcaag gatgagggca gggatgcgga taaaccacca
    57481 gagtggattt ggttttttat cattgtgcca ttgtttcgtt tcttcgtcca gacgttggaa
    57541 ttctgtttga atacgattgg cgactgtttc aatgccttca tcattcattt tcttgatatc
    57601 tgagatatcg attggatttc caaagttcat atcgacacgt tcacggctaa tcaagccctt
    57661 caaagtcatg ggaccggtgt aggtaaccgg catgatacgg accttggcca ttttggcaat
    57721 cagtgctgcg ccccccttga catcgtttga gtggcggcta ccacttggaa acatgatgag
    57781 agagcggtca ctttttttga gaacgttgat aggatatttg atggctgagg cgctgggatt
    57841 ttcacggtcg atgggaaagg cgccacacat acgaatccac caaccaaaga tacggttggt
    57901 aaagagttct ttttttgcca taaagatgaa ctgttttggc ttggtcgcaa aggccatata
    57961 aacaggatcc caccaggtac ggtgaggcgc aactaaaata taattttcat cttgattagg
    58021 aattttatca gtattatgat agtgagcatt gccattgatg gaccataaga gcaatacaac
    58081 taatccacgc aaataagtat aaaacatgcg atctccttcg attgttttct tgttattatt
    58141 ataccttatc aaaggagggc tggcaaactt ttcccttgac tagatgcata tttgggatga
    58201 aattagaatt ctgttaaaaa aaatgatata atagaattta tggataaaaa taagattatg
    58261 ggattaaccc aaagagaagt caaggaaaga caggctgagg gtttggtcaa tgactttacc
    58321 gcatcagcca gtaccagcac ttggcaaatc gttaaacgaa atgtctttac cctttttaac
    58381 gctttgaact ttgccattgc tttggccctt gcctttgtgc aggcttggag caatctggtc
    58441 ttctttgctg ttatctgctt taacgctttt tctgggattg tgaccgagct acgagccaaa
    58501 cacatggtgg acaagctcaa tctcatgacc aaggaaaagg tcaaaaccat ccgtgatggt
    58561 caggaagttg ctcttaatcc tgaagaatta gtgctaggag atgtcattcg tttgtctgca
    58621 ggagagcaga ttcctagtga tgccttggtt ttggaaggct ttgcggaagt caatgaagcc
    58681 atgttaacgg gagaaagtga tttggtgcaa aaggaagttg acggcttact tttgtcagga
    58741 agtttcctag ccagtgggtc agttttatct caagttcacc atgtcggtgc agacaactat
    58801 gctgccaaac tcatgcttga ggctaagacc gttaaaccca tcaactcccg tatcatgaaa
    58861 tcgctggaca agttggctgg ttttactggg aagattatca ttccctttgg tctggctctc
    58921 ttgctggaag ccttgctttt aaaaggcctg cctctcaagt catccgttgt aaactcgtcg
    58981 acagctcttt tgggaatgtt gcctaaggga attgcccttt tgaccattac ttcgctcttg
    59041 actgcagtga ttaagttggg cttgaaaaag gtcttggtgc aggagatgta ctctgttgag
    59101 accttggcgc gcgtggatat gctctgtctg gacaagacgg gcaccatcac ccaaggaaag
    59161 atgcaggtgg aggctgttct tccactgacg gaaacttacg gtgaagaggc tattgccagc
    59221 atcttgacta gctacatggc ccatagtgag gataagaatc caactgccca agccattcgc
    59281 cagcgttttg tgggagatgt tgcttatcct atgatttcca atcttccctt ctcgagcgac
    59341 cgcaagtggg gggctatgga gttagaaggc ttggggacag ttttcttagg ggcacctgag
    59401 atgttgctgg attctgaagt cccagaagcc agggaggcct tggagagagg atcacgtgtc
    59461 ttggtcttag ctctcagtca ggagaaatta gaccatcaca aaccacagaa accatctgat
    59521 attcaggctc tagccttgct ggaaatcttg gatcctattc gagagggagc ggcagagacg
    59581 ctgaactatc tccgttctca ggaagtgggg ctcaagatta tctctggtga caatccagtt
    59641 acggtatcca gcattgccca gaaggctggt tttgcggact atcacagcta tgtcgattgt
    59701 tcaaaaatca cggatgagga attgattgct ctggcggagg agacagcgat tttcggacgt
    59761 gtttcccctc atcaaaagaa actcattatc caaacgctga aaaaagcggg tcatacaaca
    59821 gctatgactg gggatggagt taatgatatc ctggctcttc gtgaggcgga ttgttctatc
    59881 gtaatggcgg agggagaccc ggcaacccgt cagattgcca acctggttct cttgaactca
    59941 gactttaatg atgttcctga gattcttttt gaaggtcgtc gtgtggtcaa taacattgcc
    60001 cacatcgctc cgattttctt gataaagacc atctattcct tcctgttagc agtcatctgt
    60061 attgccagtg ctttactagg tcggtcagag tggattttga ttttcccctt cattccgatc
    60121 cagattacca tgattgacca gtttgtggaa ggtttcccac catttgttct gacttttgag
    60181 cgaaatatca aacctgttga gccaaatttc ctcagaaaat ccatgcttcg tgccctacca
    60241 agtgccctca tggtcgtgtt tagcgttctt tttgtgaaaa tctttggaac gagtcaaggt
    60301 tggtctgagt tagaaatctc aactctcctc tattatctct tggggtcaat tggtttctta
    60361 tccgtattta gagcctgcat gccattcact ctatggcgag tcctcttgat tgtctggtca
    60421 gtaggaggct tcctagccac agctctcttc ccaagaatcc aaaaactgct tgaaatttca
    60481 accttgacag aacaaacgtt gcctgtttat ggtgtcatga tgttggtctt tacagtgatt
    60541 ttcatcctga ctagtcgcta tcaagctaga aaataaagaa agactgcaat ctgtggattg
    60601 cagtttttta tacgatggat ctatcgtaga tctgatgtgc aaggcctacg tgtctattat
    60661 ctatcggtga acccaagagt gattctcaag cctgcttgga ttgaggtaat agattcaaat
    60721 atctgtagtt agactatttg aagtttgatg taagaaagag aaagcgacag attgaagtaa
    60781 ttttaactct cttctattgc tagaacaaat ggtcggatag gttggtagtt tgaaaatgaa
    60841 gatgcaatct attgttaaat ggaacatagt gttatttatt agaaaatcgt ttggtttatt
    60901 tcttatcaaa tacgaaaagc aacttaaata tttcaactaa aatagatgtt atgaagaaaa
    60961 ggtaaaatga ttttggtata gtgaggttct gttctatttg atatcatatt tttgataaaa
    61021 acaaaaatgt ccattgcaaa ggacaaaatg cgaagtatat tattttttga aagcgatata
    61081 atggaatcat aaaggaggtg tatcgtgtct agaaaacaag aacaaatgga aacgttgttg
    61141 ctccttttgc gagatagtaa ggattatata tctgctaaag tattgggaga aaaattaaat
    61201 tgctctgata aaacggttta tcgccttgtc aaggtaatca acaaagattg tccggtagaa
    61261 gcattcattt tatctgaaaa aggcagaggt ttcaaattaa atccaagaag ttccctcgtg
    61321 gacgttgatg ggaattttac agaggctttt gatcctgaag taaggcgtga aaaattacta
    61381 gaacgtctct tgttgactgc tcctaagcca cattctattt atgatttagg agaggaattc
    61441 tacgtaagcg agtcagtagt actaaaagat cgtcagatat tacaagagag tctagcaatt
    61501 tatgggttag atttaaaaat gagacaacga aagcttttta ttgatgggga tgaggctcaa
    61561 attcgttcag ccattctaaa tctactgcca atgtttaatc agttggattt agagcaaatt
    61621 acacagaata aggttcagcc tcttgacgga gaacttgctc acttttgttt gggattactg
    61681 attacacttg agagagaatt gggggtaaac attccctatc catataatat aaatattttc
    61741 tctcacctgt atatttttat cagtaggaat cgtcgtagta ctagtattca tgttgtagca
    61801 ccttcaaaac ctactattgt tgatgagaaa atttacagtg tctgtcaaaa aattattcaa
    61861 gaaattgaac aatattttaa gatgaaggtt gatgcagttg agattgacta tctttatcaa
    61921 tacgttgtat cttcgagatt gcaaaaacca ttttcttccg ggaagcttcc tttttctcag
    61981 cgagttttag atgtcactca ttactatttt agccgtatgt gtatggacaa tagagagatt
    62041 gaaacgacag atcctgactt tgttgacttg gcgagtcata tcagtccctt actgaggaga
    62101 ttagataata gagtacagat taagaatagt cttttatcac aaattctttt aacctatcct
    62161 aatctagtta aagagttaac aactatttct aaagaagtga gtctagtatt tggttttgcg
    62221 tccttgagtc tggacgagat tggttttcta gtcttatatt ttgcacggtt tcaagaaaag
    62281 cgagcacgtc ctctaaaaac agtagtgatg tgtacatcag gtgtcggaac ttcagagctt
    62341 ttacgagcac gattagaaaa gcaatttact gaattggata ttattgatgt agttgcttat
    62401 catcaattag atgagctgat aaatctatat ccagatttag atttcattgt gacgacggta
    62461 gctttgcagg aaccagcaag tgtcccgttt gtcctagtta gtgtttttct aaccgagggt
    62521 gataaacaac gtcttcaagc aaaaattcag gagataaact atgaataatc tttcgcttgt
    62581 ccttatggat atatctgttc aaaatcgtca agaagcctac aaagaattag caaatcaaat
    62641 cagccttctt gtttctgaag atacagaaaa aatagaagag cttctatatt accgtgagag
    62701 acagggaagt atagaggttg ctaaaggtgt tcttctacca cattgtgaag gaaactttca
    62761 acatcatgtc ttagtgatta ctagattaaa atcacctatc agagaatggt cgaaggatat
    62821 ccagtgtgtt gaccttatta tcggtttggc cattgcagta tcacaggaca agtcatgtat
    62881 taaaacattg atgagaagac tagcagatga atcattcata aatcaattaa aacagttaac
    62941 aaaagaagaa ttacgggaga taatatatgg aaatcaaaga tattcttaat gtgagtctga
    63001 tccagacgga tttacagatg cagagcaaag aagaggtttt tgaggcatta gctcaactat
    63061 tggttgagac gggttatgtg tctgatagag accaatttat cgaaggtctg tatcagagag
    63121 aggcagaagg acagaccggt attgggaatt atattgctat tccccatagc aagagttctg
    63181 ctgtggagaa ggcgggggta gtcatagcta taaatcacaa tgagattcct tgggagacca
    63241 ttgatgggaa aggggtcaaa gtaattgtac tctttgcagt tggtgatgat acagaagctg
    63301 ctagggagca tttgaagacc ttatcactct ttgctcgaaa acttggtaat gacgaagttg
    63361 ttgccaaatt agttcgggct cagacatctg atgatgtgat tgcagctttt tgttaataag
    63421 aaaaaatttt ggagggtatc cgtatgaaaa ttgttggtgt tgcagcttgt actgtgggaa
    63481 ttgcccacac ttatattgca caggaaaaat tagagaatgc cgcaaaggta gctggacatg
    63541 tgattcatgt tgagactcag gggacaatag gggtagaaaa tgaattgagt caagagcaga
    63601 ttgatgcagc ggatgtagtt attttagcag ttgatgttaa gatttctggt atggaacgct
    63661 ttgagggtaa aaagattatc aaggttccaa cagaagtggc agtcaaatct cccaataaac
    63721 tgattgctaa agctgttgag attgttacga aataactgaa aatatttaag gagaaaatat
    63781 atgttgaaac acttaaactt aaaaggtcac ttattgacag ccatttccta tatgattcca
    63841 attgtttgtg gtgcaggatt cttagttgcc attggtttag caatgggggg tggtgttcct
    63901 gacgctcttg tagcaggaaa attcactatc tgggatgctt tagcaactat gggtggtaaa
    63961 gcccttggtc tcttgccagt tgttattgct acaggtttgt cttactcgat tgctggtaag
    64021 ccagggattg caccaggttt tgttgttggt ctaattgcca attctgttgg ttcagggttt
    64081 atcggtggta tcttgggagg ttatatagct ggtttcttgg ttcaagcgat tattaaaaag
    64141 gtcaaagtac caaactggat taaaggttta atgccaacct tgattattcc ttttgtagcc
    64201 tctttggtaa gtagtttgat tatgatttat attattggag cgcctatcgc agcctttacc
    64261 aactggttga cgagcttatt acaaagcttg ggaagtgctt caaatggttt gatgggggca
    64321 gttattggag ttctcagtgc tgttgacttt ggtggcccac ttaataaaac agtctatgcg
    64381 tttgtgttga ctttacaggc tgaaggtgtg aaagaaccat tgactgcttt gcaattggtg
    64441 aatactgcta caccagttgg atttggattg gcctatttta tcgcgaaatt actcaaaaaa
    64501 aatatctata ctcaagagga aatcgaaaca ttgaaatcgg ctgttcctat ggggattgtc
    64561 aatattgttg aaggtgtaat tccgattgtt atgaataact tggttccagg tctcattgca
    64621 acaggtatcg gtggtgctgt tggtggtgct gtttctttga caatgggtgc tgattctgcc
    64681 gtgccatttg gtggagtgct tatgttacca accatgactc gtccagtagc tggtatttgt
    64741 gctttgttag ccaacattgt agtcacagga cttgtctacg cgattttgaa aaaaccaata
    64801 aaacatacag aaccagttat gactgttgaa gaagagattg atttgtcaga tattgaaatt
    64861 ttgtaagagg gtaacgatgt caagaattga attttcacca tctttgatga ccatggattt
    64921 ggacaaattc aaagagcaga ttactttttt gaatgataaa gtagcatctt atcatatcga
    64981 tattatggat ggccattttg ttcccaatat taccttgtct ccttggttca ttcaagaagt
    65041 tcaaaaaatt agtgacacac ctttatcagt tcatctgatg gtcacagacc caaccttttg
    65101 ggtagatcaa gttctcgatt tacaatgtga gtatatttgt attcatgctg aagttctgaa
    65161 tggtcttgct tttcgtttga ttgataaaat tcatgatgca ggtctaaagg ctggtgttgt
    65221 ccttaatcct gaaacacctg tttctacaat ctttccctac attgatttac ttgacaaagt
    65281 aactattatg actgtagatc caggttttgc aggacaacgt tttttgaagt ctaccttgta
    65341 taaaatccaa gaactccgtc agcttagagt tcagaatggt tatcactaca tcattgagat
    65401 ggatggttct tcgagtcgta agactttcaa acaaattgat gtggcaggac cagatattta
    65461 tgttataggt cgcagtggat tatttggttt ggatgacgat attgccaaag cctgggatat
    65521 ctgttctaga gattacgaag aaatgaccgg aaaaacaatg ccaatcaaat aatggtttga
    65581 gaagaaattt attagttagg aggaatatat gtcactacaa tcagttaacg ccattcgttt
    65641 tcttggcgta gatgctatta acaaatctaa ttctggtcac ccgggaatcg tcatgggtgc
    65701 tgcgccaatg gcttatagct tatttacaaa acaccttaga attacacctg agcagccaaa
    65761 ctggattaac cgagatcgct ttatcttgtc tgcgggtcat ggatcaatgc tactgtatgc
    65821 tctcttgcat ttaacagggt ataaggatgt atccatggac gagattaaaa atttccggca
    65881 atggggatct aagacacctg gtcatcctga agtgacgcat acgtctggtg tggatgcgac
    65941 atctggtccg cttggtcagg ggatttctac tgccgttggt ttcgcccaag cagagcgttt
    66001 tttagctgct aagtacaaca aagatggttt tcctattttt gaccattata cttatgttat
    66061 cgctggagac ggtgacttca tggaaggagt gtctgcggag gcggcttctt atgcaggtca
    66121 tcaagcttta gataagctta tcgtcctcta cgactccaac gatatctgct tggatggtga
    66181 gaccaaagat actttctctg aaaatgttcg cgcccgttac gatgcttatg gttggcatac
    66241 agttctggta gaagatggaa cagatttagc agcaatttct acagcaattg agacggccaa
    66301 gttttctggt aagccgagtt tgattgaagt gaaaacggta attggttacg gctcacccaa
    66361 taaaagtggt acaaatgctg ttcatggtgc accactagga gcagaagaaa caggagcaac
    66421 tcgtaagttt ttgggatggg attacgatcc atttgaagta ccagaggaag tatattctga
    66481 tttcaagaca aatgtagcgg atcgtggtca ggaggcatac gatgcttggg ctagtttggt
    66541 gtctgattac aaggttgctt atcccgaagt tgctagtgag attgacgcta ttgtagctgg
    66601 aaaatcccct gtaaccatta ctgaaaaaga cttccctgtc tatgagaatg gcttctctca
    66661 agcaactcgt aattcgtccc aagatgctat taatacagca gcagcagttt taccaacctt
    66721 cttaggtgga tcggcagact tagctcactc caacatgacc tacatcaagg cagatggctt
    66781 acaagataaa tataatccat taaaccgcaa tattcagttt ggggtacgtg aatttgccat
    66841 gggaacaatc ctcaatggaa tggctcttca tggtggttta cgagtttatg gcggaacctt
    66901 ctttgttttc tctgactacg tcaaagctgc tattcggcta tcagccattc aggagttgcc
    66961 tgtaacttat gtctttaccc atgattcaat tgccgttggt gaagatggtc caactcatga
    67021 accagttgaa catttggcag gtttacgctc aatgccaaac ttgactgtta tccgtccagc
    67081 ggatgcccgt gaaactcaag cggcttggca tcatgccttg accagtacca ccactccaac
    67141 tgtcattgtc ttaacccgtc aaaacttggt agttgaagaa gggacagact ttggtaaggt
    67201 cgctaaagga gcctacgtcg tgtatgatac cccgggattt gatactatta tcattgctac
    67261 aggatctgag gtcaatctag ctatcaaagc tgctaaggaa ttggttttac aaggtggtaa
    67321 agtacgtgtg gtatctatgc cctcaaccga actatttgat gctcaagatg ctacctacaa
    67381 ggaagacatt ttaccatcta agactcgtcg tcgtgtggcc attgaaatgg cagcgaccca
    67441 aagttggtac aagtatgttg gtttggatgg cgcggtcatc ggtattgaca tcttcggtgc
    67501 gtctgcccca gctcagactg tgattgataa ttatggattt acggtagaga atatcgttgc
    67561 tcaagttaag tccctataga aaccaattac aatgaagata cagctgttgt cagactagca
    67621 gatgtagtga tagacactaa tcagatgatt ggttatttaa aaactataat gagaatgtaa
    67681 taatttatct acgaaagtta tagtagatag tatacacaat agagtatacc ctgaaacggt
    67741 tgcgaagtac gctaatcact ttgctactga tctagatagt ttctttaatc aataaacaca
    67801 gcatccacag attgacttag gatattgtaa gttttttgaa agctagagag aaggtctcta
    67861 aaattaaaaa acgcatagta taggatgttg aaatgatgaa ctgcccccca aaagttagac
    67921 agaaaaaatc taacttttgg ggtgttttat tatgaaatta agttatgaag ataaagttca
    67981 gatctatgaa ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa gatttggtgt
    68041 ggatgtttct ggtctaaagt acatggtgaa attaattgac cgttatgg
//
LOCUS       DAVBNZ010000004        64454 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000004 DAVBNZ010000000
VERSION     DAVBNZ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64454
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.004"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VQ860_000213"
     CDS             complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VQ860_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET3118716.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VQ860_000214"
     CDS             complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VQ860_000214"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET3118717.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VQ860_000215"
     CDS             complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VQ860_000215"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET3118718.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3795..5063)
                     /locus_tag="VQ860_000216"
     CDS             complement(3795..5063)
                     /locus_tag="VQ860_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET3118719.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5183..5551)
                     /locus_tag="VQ860_000217"
     CDS             complement(5183..5551)
                     /locus_tag="VQ860_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET3118720.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5544..5810)
                     /locus_tag="VQ860_000218"
     CDS             complement(5544..5810)
                     /locus_tag="VQ860_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET3118721.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VQ860_000219"
     CDS             complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VQ860_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET3118722.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9378..9947)
                     /locus_tag="VQ860_000220"
     CDS             complement(9378..9947)
                     /locus_tag="VQ860_000220"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET3118723.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VQ860_000221"
     CDS             complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VQ860_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET3118724.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11217..11411)
                     /locus_tag="VQ860_000222"
     CDS             complement(11217..11411)
                     /locus_tag="VQ860_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET3118725.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VQ860_000223"
     CDS             complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VQ860_000223"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET3118726.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VQ860_000224"
     CDS             complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VQ860_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET3118727.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAEVIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14345..15103)
                     /locus_tag="VQ860_000225"
     CDS             complement(14345..15103)
                     /locus_tag="VQ860_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET3118728.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15161..16342)
                     /locus_tag="VQ860_000226"
     CDS             complement(15161..16342)
                     /locus_tag="VQ860_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3118729.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGKIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16525..17004
                     /gene="rlmH"
                     /locus_tag="VQ860_000227"
     CDS             16525..17004
                     /gene="rlmH"
                     /locus_tag="VQ860_000227"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET3118730.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17048..17121
                     /locus_tag="VQ860_000228"
     tRNA            17048..17121
                     /locus_tag="VQ860_000228"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17082..17084,aa:Arg,seq:tct)
     gene            17286..17411
                     /gene="comC"
                     /locus_tag="VQ860_000229"
     CDS             17286..17411
                     /gene="comC"
                     /locus_tag="VQ860_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET3118731.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17432..18757
                     /locus_tag="VQ860_000230"
     CDS             17432..18757
                     /locus_tag="VQ860_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3118732.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18754..19506
                     /locus_tag="VQ860_000231"
     CDS             18754..19506
                     /locus_tag="VQ860_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3118733.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19558..19629
                     /locus_tag="VQ860_000232"
     tRNA            19558..19629
                     /locus_tag="VQ860_000232"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19591..19593,aa:Glu,seq:ttc)
     gene            19635..19708
                     /locus_tag="VQ860_000233"
     tRNA            19635..19708
                     /locus_tag="VQ860_000233"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19669..19671,aa:Asn,seq:gtt)
     gene            complement(19749..20291)
                     /locus_tag="VQ860_000234"
     CDS             complement(19749..20291)
                     /locus_tag="VQ860_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET3118734.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20470..21237
                     /locus_tag="VQ860_000235"
     CDS             20470..21237
                     /locus_tag="VQ860_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET3118735.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21241..21660
                     /locus_tag="VQ860_000236"
                     /pseudo
     CDS             21241..21660
                     /locus_tag="VQ860_000236"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21688..22002
                     /locus_tag="VQ860_000237"
     CDS             21688..22002
                     /locus_tag="VQ860_000237"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET3118736.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22103..24655)
                     /locus_tag="VQ860_000238"
     CDS             complement(22103..24655)
                     /locus_tag="VQ860_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET3118737.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILFTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDILAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24717..26339)
                     /locus_tag="VQ860_000239"
     CDS             complement(24717..26339)
                     /locus_tag="VQ860_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3118738.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26545..27570
                     /gene="trpS"
                     /locus_tag="VQ860_000240"
     CDS             26545..27570
                     /gene="trpS"
                     /locus_tag="VQ860_000240"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET3118739.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27722..29200
                     /gene="guaB"
                     /locus_tag="VQ860_000241"
     CDS             27722..29200
                     /gene="guaB"
                     /locus_tag="VQ860_000241"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET3118740.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29251..30348)
                     /gene="recF"
                     /locus_tag="VQ860_000242"
     CDS             complement(29251..30348)
                     /gene="recF"
                     /locus_tag="VQ860_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET3118741.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30351..30719)
                     /gene="yaaA"
                     /locus_tag="VQ860_000243"
     CDS             complement(30351..30719)
                     /gene="yaaA"
                     /locus_tag="VQ860_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET3118742.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30878..32128
                     /locus_tag="VQ860_000244"
     CDS             30878..32128
                     /locus_tag="VQ860_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3118743.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAELEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32125..33408
                     /locus_tag="VQ860_000245"
     CDS             32125..33408
                     /locus_tag="VQ860_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3118744.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33450..34271
                     /locus_tag="VQ860_000246"
     CDS             33450..34271
                     /locus_tag="VQ860_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3118745.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34282..34827
                     /gene="pgsA"
                     /locus_tag="VQ860_000247"
     CDS             34282..34827
                     /gene="pgsA"
                     /locus_tag="VQ860_000247"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET3118746.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34824..35651
                     /locus_tag="VQ860_000248"
     CDS             34824..35651
                     /locus_tag="VQ860_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3118747.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35636..36475
                     /locus_tag="VQ860_000249"
     CDS             35636..36475
                     /locus_tag="VQ860_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3118748.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36468..37262
                     /locus_tag="VQ860_000250"
     CDS             36468..37262
                     /locus_tag="VQ860_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3118749.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37321..38139
                     /gene="mreC"
                     /locus_tag="VQ860_000251"
     CDS             37321..38139
                     /gene="mreC"
                     /locus_tag="VQ860_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET3118750.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38139..38633
                     /gene="mreD"
                     /locus_tag="VQ860_000252"
     CDS             38139..38633
                     /gene="mreD"
                     /locus_tag="VQ860_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET3118751.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38727..39905
                     /locus_tag="VQ860_000253"
     CDS             38727..39905
                     /locus_tag="VQ860_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3118752.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40129..40908
                     /gene="rpsB"
                     /locus_tag="VQ860_000254"
     CDS             40129..40908
                     /gene="rpsB"
                     /locus_tag="VQ860_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET3118753.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40987..42027
                     /locus_tag="VQ860_000255"
     CDS             40987..42027
                     /locus_tag="VQ860_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET3118754.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42273..42560
                     /gene="tnpB"
                     /locus_tag="VQ860_000256"
     CDS             42273..42560
                     /gene="tnpB"
                     /locus_tag="VQ860_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3118755.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(42751..43019)
                     /locus_tag="VQ860_000257"
                     /pseudo
     CDS             complement(42751..43019)
                     /locus_tag="VQ860_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43016..43414
                     /locus_tag="VQ860_000258"
     CDS             43016..43414
                     /locus_tag="VQ860_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3118756.1"
                     /translation="MDAPIPKAPLAHSFGSASIIAHIIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(43611..44531)
                     /gene="cysK"
                     /locus_tag="VQ860_000259"
     CDS             complement(43611..44531)
                     /gene="cysK"
                     /locus_tag="VQ860_000259"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET3118757.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(44816..45451)
                     /locus_tag="VQ860_000260"
     CDS             complement(44816..45451)
                     /locus_tag="VQ860_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET3118758.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            45507..46805
                     /locus_tag="VQ860_000261"
     CDS             45507..46805
                     /locus_tag="VQ860_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3118759.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            46802..47464
                     /locus_tag="VQ860_000262"
     CDS             46802..47464
                     /locus_tag="VQ860_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET3118760.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            47544..48092
                     /gene="raiA"
                     /locus_tag="VQ860_000263"
     CDS             47544..48092
                     /gene="raiA"
                     /locus_tag="VQ860_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET3118761.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            48228..50201
                     /locus_tag="VQ860_000264"
     CDS             48228..50201
                     /locus_tag="VQ860_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET3118762.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            50198..50650
                     /gene="rplI"
                     /locus_tag="VQ860_000265"
     CDS             50198..50650
                     /gene="rplI"
                     /locus_tag="VQ860_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET3118763.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            50694..52046
                     /gene="dnaB"
                     /locus_tag="VQ860_000266"
     CDS             50694..52046
                     /gene="dnaB"
                     /locus_tag="VQ860_000266"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET3118764.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            52048..52314
                     /locus_tag="VQ860_000267"
     CDS             52048..52314
                     /locus_tag="VQ860_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118765.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            52403..53749
                     /gene="cbpD"
                     /locus_tag="VQ860_000268"
     CDS             52403..53749
                     /gene="cbpD"
                     /locus_tag="VQ860_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET3118766.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDSGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKIKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAINTTVDGYRVNSDGERV"
     regulatory      53832..53934
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            54005..54295
                     /locus_tag="VQ860_000269"
     CDS             54005..54295
                     /locus_tag="VQ860_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET3118767.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAVQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            54258..55016
                     /locus_tag="VQ860_000270"
     CDS             54258..55016
                     /locus_tag="VQ860_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3118768.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            55054..56061
                     /locus_tag="VQ860_000271"
     CDS             55054..56061
                     /locus_tag="VQ860_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3118769.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            56061..56789
                     /locus_tag="VQ860_000272"
     CDS             56061..56789
                     /locus_tag="VQ860_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118770.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            56908..57366
                     /locus_tag="VQ860_000273"
     CDS             56908..57366
                     /locus_tag="VQ860_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET3118771.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            57368..59800
                     /locus_tag="VQ860_000274"
     CDS             57368..59800
                     /locus_tag="VQ860_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3118772.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYELDRLEEVALELTETDYSQDETFTELPFSRRLQILFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQACSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            60442..61095
                     /gene="rr06"
                     /locus_tag="VQ860_000275"
     CDS             60442..61095
                     /gene="rr06"
                     /locus_tag="VQ860_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET3118773.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            61092..62423
                     /gene="hk06"
                     /locus_tag="VQ860_000276"
     CDS             61092..62423
                     /gene="hk06"
                     /locus_tag="VQ860_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET3118774.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDIYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            62506..63033
                     /locus_tag="VQ860_000277"
     CDS             62506..63033
                     /locus_tag="VQ860_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET3118775.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAVVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            63112..>64454
                     /locus_tag="VQ860_000278"
     CDS             63112..>64454
                     /locus_tag="VQ860_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET3118776.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGST
                     QAATFSNMANKSQTEQGEINIERDKAKTAVSEYKEKKVSEIYTKLERDRHKDTVDLVN
                     KLQEIKNEYLNKIVQSTSKTEIQGLITTSRSKLDEAVSKYKKAPSSSSSSGSSTKPEA
                     SDTAKPNKPTELEKKVAEAEKKVEEAKKKAKDQKEEDYRNYPTITYKTLELEIAESDV
                     EVKKAELELVKEEAKEPRNEEKVKQAKAKVESEETEATRLEKIKTDRKKAEEEAKRKA
                     AEEDKVKEKPAEQPKPAPAPQPEKPAPKPENPAPKPENPAPKPEKPAEQQAEEDYARR
                     SEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYY
                     LNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQYNG"
BASE COUNT        20215 a        10985 c        12757 g        20497 t
ORIGIN      
        1 ttatttttcg tcattcattt ttgactttac ttcatcatag gatagtgcat gagattcctc
       61 ttctactgct tcaggcatct ttcctgtttc gtaaagagct ttaatttgtg tactatccaa
      121 tgtttcgtat ttcaataatg cttctgcaat taacttgtga atttcacgat ttgactgaat
      181 aatttcagca gctttatttc gtgcctcatt taataatgaa cgaacctctt catcaatttc
      241 ataagctgtt tgttctgaaa ttgatttttg aggactctgt gcaccaaaca tagcatggtt
      301 tccttcatat tgtactgggc caagtttttc actcataccg tactctgtaa ccattgcacg
      361 cgccatttgt gtcgcttgtt caaagtcgtt tgaagctcct gtagtttgga cattaaagat
      421 aatttcttca gctacacgtc cacccattaa gccagccaat tgctctttca tatcttcttt
      481 agatagaagc atttgatcct ctttaggaag tgcaatcatg tatccgcctg cacggccgcg
      541 tggtacaatt gtaaccttat ggacaacgcg agcattcgac aagactagac caacaatggt
      601 atgtcctgcc tcatggtaag caaccaattc tcgttctttt tgtgaaactg tcttatcttt
      661 cttagaaggt ccagcaataa ctctatcttc tgcttcatca atatctgaag catcaattat
      721 cgatttattg cgacgagcag caactaaagc tgcttcattc aagacattct ctaaatcagc
      781 accaacaaag cctggagttt gttgagccac taatttcaaa tcaacatctt ctgctaaagg
      841 cttgttctta gcgtgaactt tcaagattgc ttcacgacct ttaacatcag gacgaccaac
      901 caatactttt ctatcaaaac gtcctggacg caaaagggca ggatcaagta catctgaacg
      961 gtttgtcgca gcgatgacga taatcccttc atttccctca aaaccatcca tctcaatcaa
     1021 aagttggttc aaggtttgtt cacgttcgtc attacctccg ccgagaccga ctccacgttg
     1081 acgtccaaca gcatcaattt catcgataaa gatgatagct ggtgctgctt ttttggcatc
     1141 ctcaaaaaga gagcgaacac gactagctcc aactccgaca aacatttcta caaagtcaga
     1201 acctgagata ctaaagaatg gaacacctgc ttctccagcg actgccttag caagcaaagt
     1261 tttacctgtc cccggaggtc cctccaaaag aacacctgct ggaatacggg ctccaagttt
     1321 tgtgaatcgt tttggatctt ttaagaactc aacaacttca actagttctt gtttttcttc
     1381 ctcagctcca gcaacatctg aaaatcttac tttaatatct tctttatttg ctgctttagc
     1441 cttactacgt ccaaaactca ttggattacg gccattgcct cctcccatat ttcccatcat
     1501 agagaatagg aagaagaata gaattccaaa tggcacaatg gatacgagta gattaatcca
     1561 tataccactt gaactttcat gcttaacagt tacttctgct ttatggtcag tagcaagttt
     1621 ttgcaattct gatacggtag tatctgcagg aagaatagtg ctggtaaatt tctctacctt
     1681 agtaacagat ggcgtgaaaa actgaatacc tgtttcttct ttacttgttt taggattttt
     1741 atagacacca gaaacttcga taacactacc atttggttgg taagttaatt cttttacatt
     1801 accatcggta atttcttgta ccaactcagt atagttgatt tgctgacttc ctcctgagtt
     1861 attcccagaa tagaaatact ggaatcctgt cacaaggaaa aagataaata ataaccatag
     1921 aaaaggattt ttaattaaac cattattttg ttttttcatt aaagattatt ctttctaatt
     1981 tgaatacact tcctctttca atactccaat ataaggaaga ttacgataat tttctttgta
     2041 gtctaaacca taacctacta caaactcatt tgggatagta aagcaggtat agtctgcctc
     2101 aatttctaca acacgtcctt ctggtttatc caacaaggtt gcaattttaa cagaagctgc
     2161 ttctcttgct ttaaacatat ctcgcaaatt cttcaaagtt tgacctgtat caatgatatc
     2221 ttctacaaat agaacatgtc ttcctttgat atcttgagtc acatcttgtt taatattgat
     2281 aacaccacta cttgctgttc caccatggta gctagaaacc atcatgaagt ccatttcaat
     2341 atgtgtatca atatgtttga ccaattcagc cataaaagga atagatcctt ttaaaatccc
     2401 aactaagatt ggattttttc ctgcatagtc tttagttaat tgagcaccta gttttttagc
     2461 tgcttctgta atttcatcgt gtgaaacgag gactttttta atatcgtttt ctaacatttt
     2521 ttacctatct attttttcta tataaagtac agtgttcatt atatcatttt tcgttttttt
     2581 actcaaatta ttggtcgcaa ttcccaaaat tgagacaatt tcaccaaatt gctcaataat
     2641 aagagcagag tttctctttt ccatagggat tttcaaatca ataaataaac gtctgagttt
     2701 ttttctatgc ccattttgaa tcaaaacatc tcctgttttt cgatgacgaa tgtgtatgga
     2761 tgtttcacgt gaaacaggta tttgttgaat tgattcacct tctaatggaa gtccaaagga
     2821 aaataaatat ccttgataag ctacctgatt ttgatagtgt aacacaagtt catcttcctc
     2881 ttcatcagcc tgcggactga ttttacaaat ctgaaactgt tggtactctt ttatcaattc
     2941 atagccattt ttaatcggat gacgatactg gcttttagat tttaaaatct gctgaacttc
     3001 agcaaactga gcttttgtaa gattcaaatc tggaaaacga ttcagataag tttgaagtaa
     3061 aactctttgt gtagactcag agtaagaaaa taactgctgt aaatcttcca cattaatatt
     3121 gttagataat tcagctattg ccaaatcata atctaaaatt tcattgccaa tgcctaagat
     3181 tgcatcccta aatcgaggat tttctttttc caattctggt aagtaagagt ttcgaatacg
     3241 atttcgaaaa taatgattct cctgatttga tgtatcttca aagtgaaaaa ttgatggaaa
     3301 gtcttttttc tgaaaatgca agaagggacg aatgatttct atctctccga ctacttgctt
     3361 ctccttaatt cctgatagat agcgcaagcg agttcctcga atcaagcgca tcaaaatcgt
     3421 ttccacctga tcatcagcat ggtgggcagt gactaaagct gtcgcacctg tctttttcat
     3481 gacctcttga aaaaaatcat aacgaaaatt tcgtgcacgc gcttctgaaa attctcctga
     3541 aaaattgctg atataaatag gaagctctgc ttcagcagcc aacttcctta attccttttc
     3601 ttcccaatct gattcaattc tctgcttatg attcacatga gctagaatca attcaatctc
     3661 taactctttt tgataagtag acaatacctt aaatagaaac atggaatcta atccaccaga
     3721 aagagctaga accgccttag catgcttttt gaaatatccc ttcttgagaa aatgatttaa
     3781 aaaatctggt tccctcattt tagaacctca taaacatcct tggctatctt agaaatcgta
     3841 tcataatcag aattcttagt gaaaatagaa agaataaatg gagaatctgc atagacaaca
     3901 cccgtatcat gcttaaattc atccgcatct ccaattttat gagctacttt aacagaaaca
     3961 cctttggcaa ttcgctgact atcaaaatct gttttagtca aagactctaa cacaaatcca
     4021 ttttgattat aaatagcttc cataaacttc ccggccatct tagaagaaat caatttttct
     4081 tttggatccc aatcatctcc cataatggca gacatcttgg atttgaatgt ggcatcagat
     4141 tggtttgaaa tgtaatatcc caatagatta tgagctacat tatcagattc ttttgatact
     4201 ttcgtaatta aatcctttaa agaatattct ttattatctt cttttttagg aagactacca
     4261 cttccctctg gtttataaga acctggaaaa tcattgactg cagatacgta ttttacagtc
     4321 gtatctaact gataaagacc ctcatttatt ttttcttgcg tataatagag ataagagagt
     4381 ttcaaaacgc tggctgcata catcttttca tcttgattga taccagcttc ttttccagta
     4441 gtcagttgct taacataaat agagaaagaa tctttctgat atttttcaga taacatttct
     4501 tgaactttac tcatccgatt atcttcttca gaagttgatt ctttagctac ccatccagcc
     4561 tgatcaatat gtagaaattc tcttccttct acaaacatgg tcttgtcgat tgatacttgc
     4621 gaataagctg ataaggatga tttcacttct tttaaatcat aaggactatt gtacagttta
     4681 aagtcagatt ctaaccatgc tttttttatt gttggagtta cctctgattg atcatataaa
     4741 aatcgtttgt ccgcagctat aaattgatga tttgatagct taaatactgg aattccttgt
     4801 ttatttaagc gccactcggt tatttgaaaa cttgttttgg gagtcaattt cccagattcc
     4861 actactaaat cttcattcgc ataaacagga acctctccat aaaccatggg agaacttaat
     4921 ttttctctaa aataaatacc aaagtcagat tgtgaaaggt aataaatttc tttcgaagta
     4981 tagacgactt ctttttctgt actaacgact tttgaaatgg tcaaaaaact tggtagcaac
     5041 aaaataatta agaatttacg cattcttcct ttccttttct tcttgtaaac gcaataattg
     5101 atttttatca gccaattctt ccagcttttc atctgacaaa ctcaaaaatt gctctattac
     5161 gtctaataaa ttttccattt tatcaccttt gaagcaagtc aggaatcgta taaacttttt
     5221 ccctcgactt agaataatag tacttcgctc gtgtatattt ggcagcataa tcttcatctt
     5281 tcaacttggt agcaaatgct gtctccttat ccttttcatc actcaaagtt tgatactgag
     5341 tttgcaagtc tgctaattgc tgacgtcttt ggagtaattg ctgataactc tgcgctaaat
     5401 taaaagttgg caagataaat aatagcataa tcaaaatcaa tacccctccc ataaaacgat
     5461 tccgtttttg tcgttctttc atcaggtagc gacgacgttg gtattcattt tgaataaaag
     5521 aattattcaa ttgtacaata tttttagaca ttttcttcta cccgtgtttc actgataatt
     5581 tcatacattc ctgctgcatc ttcttttttt gtactatctt tcatctctag tacttttaca
     5641 agcagcaact tattgccaaa gcgaatttca acttggtcat taactttcaa gtccgttgaa
     5701 cttttggcca agattccatt aaccttgatt ctacctttat ctgctacttc ctttgcgact
     5761 gtacgacgct tgataattcg cgatactttt aaatatttat ctaatctcat ccttattacc
     5821 tcaatttatt attgtaccat ttttatctat tttatagaag aaaaatatca aatggaattt
     5881 tcttccttag actcttttat ctctaataaa ctttctccaa aaatcagcag accttctaaa
     5941 atttcataat ctttcttatt ttggacatca aatacaagct ccattaatcc cttattctca
     6001 gcgatgcctg cttttaagtt cgttacggat aaagctttaa aataatcttg agctaaaaac
     6061 aatcgttgag tgactttttc aaattgaatt gtaattttat tatcttttct ttccacacgt
     6121 tgaacaaaga ccttgtccaa gtatgattta accaaaccaa tctctaaaag ataggctact
     6181 acatctgggt attctccaaa acggtctatc aactcctctt gtaactcttc ataattgaca
     6241 cggttgtcaa tttgacgaat tttcttgtaa atttcaatct tatgtcgttg atcagaaata
     6301 taagtatcag gaagataggc atcaatttgc aaaatcaact cagcattccc tttggttctt
     6361 gtgttagcgt tagcattacc gtttcgttta gcaatagctt cctctaataa ctgcgaatac
     6421 aattcaaaac caacagaatc aatgaaacca gactgggatt ttcctaaaag atttcctgct
     6481 ccacgaatcg aaagatctcg cattgcaatc ttaaagccag agcccaattc tgtaaatcct
     6541 ttaatcgctt ctaatctctt ttcagagact tcactgattg atttttctgg acgatacatg
     6601 agataagcat aagcaatacg attactacga ccgactcttc ctcttaactg atataaggtt
     6661 gacaagccca tatggtccgc attttcaata aataaagtat tagcatttgg aatgtccacc
     6721 cctgtctcaa taatagtagt cgtcaccaag atatcgtatt gtccctcaat aaagtctaat
     6781 agagtatttt ccaactggac ttcactcatt cgaccatgaa catatccaat cgaagcctct
     6841 ggaatcaact cctgtaattc tgaaaccttc tgaacaattg tatcaacttt gttgtaaaga
     6901 taataaactt gacctccacg ctccatttca cgcaagacag catcacgaat gacactatca
     6961 ttcttttcca aaacataggt ctgaacagga tagcgattag tcggcggagt ttcaataaca
     7021 gacaaatctc tgattcccag catagacata tggagggtac gagggattgg cgtagcggtc
     7081 aaggttagga catccacttg tttcttcagt tctttcaaag tttccttatg cttgacacca
     7141 aatcgctgtt cctcatcaat aatcatcaag cccaaatcag caaacacaac atcttttgac
     7201 aaaacacgat gtgttccaat caaaatatcg acttgaccgt ttttcaattt ttcaagtgtt
     7261 gcagtctgct cttttttact tctaaagcga ctcaacacat caacattaac tgcaaaattt
     7321 tggaatcgtt ccttaaaatt cgtatagtgc tgttgcgcta aaaccgtcgt cggaactaga
     7381 atgacaacct gtttgtgatc attgactgct ttaaaggctg cacgcatagc aacttcagtc
     7441 tttccaaaac caacatcccc aactaaaagt ctatccattg gctgagaagc ctgcatatcc
     7501 ctcttgattt cctcaatact acgaagttgg tcatccgttt caacataagg gaaagcatca
     7561 tcaaaggcat cttgatcatc atcatcagct gagaaagcaa aacccttcaa ctgactacgt
     7621 tcagagtaga gtttgattaa atcatcagct atatcctcta cctggttctt aaccttttgc
     7681 ttggcctttt taaaatgacc gtcatttaat ttattgagtt ttggagcttt accatcactt
     7741 gaaatatatt tggacagtag atgaatctgt tccacgggaa tagaaatttg atcaccattt
     7801 tggtattgga cactgacata atcacgatga attcccttga tttcaatggt ttcaattcct
     7861 agatattgac caatcccatg gatatgatgg acaacatagt cccctttttc aagttcattg
     7921 taatctttta atctctctgc atttgaaaca tgttgtcttc gaaaacgacg ctttaatttc
     7981 ttttgaaaaa tctcatgttc agttatcaat aaaatctttt catctacaaa atgaaaacca
     8041 tgtctgagat taccttctat taagtttaca gattctttac agatacttgt cttatctcta
     8101 gaatccaatt taatctgata ttcctctaac atatcctcca atgttttact tcccattgaa
     8161 ttgctagact gcagaataat ggtgtaatcc atttttttat atcgttcaat ttcttctttt
     8221 agaaaagaaa actgattgaa aaattcctgc ataggatatt gattgaattg ataaattttg
     8281 tcaaatttga gatttcctaa acccttttga agattagaga aaaaggtcac tggactttgt
     8341 tttttataga tttgttcaat atcagaaaaa tactgcatat cagaaaatgc tttactattc
     8401 tgtaattctt ctgtaaagta ctgcgctaat tctctttcaa agacttcata ctgattcatc
     8461 aatttttgat aatcatcaaa gaatattgga gtatcttttt caatataatc aaagacagtc
     8521 catgtcttat catagcacaa agataaaaac ttccgagaat ctgcatgact ttgcttttga
     8581 tgaaaacttg aaagaatttc ttctaggtat gatttcaaaa taggtgataa agtttttgaa
     8641 atttgttttt ctaaagctga ctgtcctcgt tgataatcct tttctctcaa aagcatatca
     8701 ctagctggaa agatagtgag ttctgtctta ttttctttcg ataattgtgt ttctacttca
     8761 aatgacctga taccatcaat ttcatcacca aaaaactcaa ttcgacaagg ttctaactgg
     8821 gatatttcaa aaatatctaa aatatctcct cgaagactaa attcaccctg agtttgtact
     8881 tgagtaactt ttcgatagcc attttccttt aactgatgga taaacgcgtg ttgagcatat
     8941 tcttcaccaa ctgagatttt tacaatacta tctttgaatg cattgggaga cggtaaaatc
     9001 aatcgacttg ctgcgatatt acaaactaaa atccctttct tagatgaatc agtcaaaaaa
     9061 cgcaaggctt caacccgtga aataattttt tcctgtgaag acatcaaaaa ctccaccata
     9121 ggagcatcat ctaccaaaaa tggatagacg agttcctcac ccaagataga aataagatca
     9181 ctaacaagtc cttctgcttc tccataagtt gacgtcaata acacaatcct atcttctttt
     9241 tctaaactgc ttgcaattgc aagagcctta gtagatgttg ataaaccaag tattagttgt
     9301 cttttcttat ctgttaaatt ttgatgccat tttttaatct gatcattttc tgagaataaa
     9361 tctaataagg tcaccattta tccgttatac ctctgcattg ttttctcaaa atttttctct
     9421 tgtaaatagt agtttacaga atcgtcaact ttgtcaacag actgtaaaat accgatataa
     9481 tcatccctgt caaacttact caaaacatga tgaacaactg acataccatt tttaggtctt
     9541 ccaattccaa tcttaacacg gttaaagacc tgagttccta tatgttgaat aatagacttg
     9601 ataccattat gaccacctgc tgagcctttt gctcttaaac gaattttccc aacttccatg
     9661 tcaagatcat cgtaaatgat aagtaaatcg tcaatatcca aaccatagta agttaataaa
     9721 gcatgaactg cttttccact ttcattcata aaggtcgttg gtttaaccag ataaattttt
     9781 tctccattta ggaaaaagga tgctaggtca gcttgaaata tcttatcgtg tgtaaaagtg
     9841 acattctgtt tcttcgctag ttgatcaatc aacataaaac caacattgtg ttttgtttca
     9901 aaatatttat cccctggatt tcccaagcct acaagtaatt tggtcattta tttttccttt
     9961 caaaagccaa aagggttgga atttttttcc aacctaattg acaccattta ttaattttta
    10021 gacattaaag cggaattcca tgatatcgcc atcttgaacg atatattctt ttccttcttc
    10081 acgcaagcgt ccagcttctt ttacggcctt ttcagatccg tatttcacta gatcttcata
    10141 tgacatggtt actgcacgaa taaagccttt ttcaaagtct gagtggataa taccagctgc
    10201 ttgaggagcc ttcataccac gtttgaaagt ccaagcgcga acttcttttt caccagctgt
    10261 gaagtaagtt cccaatccaa gcaagtggta agctgcacgc gtcaacttat ctacacctga
    10321 ttctgtcaaa ccaatggctt caagaaactc ttttttatct tcatcatcca attcagaaat
    10381 ttcttcctca gcacgcgcag aaataacgac tacttcagca ttttctgtcg ctgcaaattc
    10441 acgaatttgt ttgacatagt cgatagagtc aggttccgaa accacatcct catccacatt
    10501 agctacataa agaactggtt tagtcgtcaa aaggaaaaga cctttgacaa ccttttgttc
    10561 ctcatctgta aattcaatgg tacgagctga tttcccatct tctaggactg gtttaatctt
    10621 ttgaagaaca ttgaattctg ctactgattc tttatctttt tgcgtacgtg ccatcttttc
    10681 tacacgcgca tatcgtttgt tcactgattc taagtcagca agaatcaatt ccagattaat
    10741 ggtatcaata tctgcaagcg gatctacaaa ggcgtcttca cgtccttgct cgcgcatcac
    10801 attttcatca tcaaaagcac gaactacgtg aacaatcgca tctacttcac gaatattggc
    10861 caagaattta ttccctagcc cctctccttt tgaagctcct tttacaatcc ctgcaatatc
    10921 tgtaaattca aatgttgtgg gaactgtctt tttaggagtt atcatttcag ttagtttttg
    10981 tagacgttca tctggaactt ccaccattcc aacatttgga tcaatcgtcg caaatgggta
    11041 gtttgctgcc tctgctcctg cttttgtaat tgcattaaat agtgttgatt taccaacgtt
    11101 tggcaaacca acgatacctg ctgtcaaagc catatttctc attctccgtt ttcatttcaa
    11161 tccctaatat tataacacaa aaagggataa agtgctaacc ctctaactaa gggttctcag
    11221 tcaataattt tattcatttt tcgctcaaaa tcatatcgcc ccatcatgac aacatgctca
    11281 caattactgc attttatttt gatatctgct cctacacgtg taatttccca acgattagcc
    11341 tttttaccag tcgacttgat tgtacaagcg tgtggttttt tcatctcaac aaaatttcca
    11401 acttgataca tactactctc cttttctttt tcgattatat cataaaagag gcgagccagg
    11461 ctcaacctct ttcacttaat ttgtacgaac tggtgtaatg agctgcatga agtcttcgtc
    11521 agtatctgct ggcacaagag taaatggacg aacagctgag ataaagctaa tggtcacctt
    11581 ttcgctattt aaagctttaa gagaatcaat caagtaagtt gggttgaaac taatggtcaa
    11641 atcttcacca gtaacctgat cagtatcgat ttcttcgttt actttaccaa cttctggaga
    11701 gtgaacatgg gcgctaacaa ccccatcctt aatttcaagt ttcacagtac cattttgagt
    11761 cgcacttgat aaaagacggg cacgctccat tgactggcgt aagtttacca cattaaaagt
    11821 aatagtagtg ttaaagtctg ttggaatcaa gcgatctgta tcaggatagt ttccttctag
    11881 gagacgagta tagaagctaa tattttcgct tctaaagagg atttggttat tggcaaagaa
    11941 aatctctaca gtttcgatat catctgtaaa taccgctgaa aattcgcgta gagaacggct
    12001 aggaattacg acatcaaaat catcactatt tttttcaaga gtcaattttt tctggcttag
    12061 gcgatgagag tctgttgcaa ctgtttttaa ctctttgtgt tgactcaata cgaagtggac
    12121 acctgttaaa atcggacgac tctcttgtgt acttgcagca aaggctgttt cattaataat
    12181 tttcttgagt aattttgttt caagtattaa aggagtgctt gctgaaattt cttggattcg
    12241 tggatattgt tcgctatctt ttccttttag ggtaatttct gatttgccac tggttaaaac
    12301 aatttgattt tgttcaattt ctttaaaatc aagagttaca tcaggtaaac tagatactac
    12361 attgataaag aaagaagctt caagaaggat cgaacctaaa gaagtaatca acaaaccagc
    12421 atcttcattt ttttgagaaa taaaattttc aattgagatt tgaccatttg aaccaattaa
    12481 agtaatacct tcattggtca cgtcaatttt tactgttgat aaaataggaa tggcattttt
    12541 agaactaata gctctcttag tagtatttaa tgcttgtaga aataaatttt tattaattga
    12601 aaaatgaatc atggattctc ctttatttat ttttagtatt agaaagataa tagtaataat
    12661 agagtctgtg aaatctgtgg aaaacagcct ttaaacaagt cctatcaagt tttttagctt
    12721 gtttaaaaaa tgtggataaa aaagataaaa aactaaaagt tatccacaaa ttatttgatt
    12781 ttctttttga ttgattcaat ttctaaacgt aaattatcgt cttgatcaat caaagatttt
    12841 attttggcat gggcatgaat gactgtggta tgatcttttc ccccaaattc cttcccaatt
    12901 tttggaagac tattatctgt tagttctcta gataaataca tggctacttg acgggccaaa
    12961 acaatatttt gaaggcgtct acttcccttc atttctttga tactaacacc ataaaagtta
    13021 ccaacttcag tttggatttt atcaattggg atgacgagca tttggctaac atcttgtttg
    13081 cgggctctaa tggcttctgc agcaatatca atagtgatat ccttgatttt ttttactctg
    13141 gcaattaaag tgatgtcgtt gatggctccc tcaagatctc gaacatttga atcaaattgc
    13201 ccagctaggt attctagagt atcactttgg aaattgtagc ctaaatgttc cgttttactt
    13261 tgtaaaatgg caatacgtgt ttcaaagtca gggggtgtga tagtttgtgt caatccccaa
    13321 ctaaaacgcg tgacaagcct ctcctcgagc ccttctagat gttttggact acgatcactc
    13381 gttaggacaa tctgtttttg cttgtcatga agggcgttaa aggtattgaa aaattcttcc
    13441 tgagttgcga ctttttttcc gctgagtgac tggatatcat cgattaacaa aagatcaaga
    13501 ctacgatagg tctttttaaa cttttccatt tccccaagtc ttaggtgatc aagaaagtca
    13561 ttaataaagc tttcggcagg gatatattta acacgcgcat taggaatatt ttttagaatt
    13621 tcatttccaa tagcgtttaa taagtgagtc ttaccaaggc ctggtcctcc atagataaaa
    13681 agagggttat aggtcagagc caaatcttca gagacagcta aagcggctga tacagcccaa
    13741 acatttccat ccccttgaat aaagttatca aaggtatact tttcttttaa tcccgtatct
    13801 gaataaggaa tagatactaa ctttggacta tagtcataaa gagttaaatt tgtagcttct
    13861 tcaacttgtg agctagtcgt atcttgaggt ttggtgaaaa tatagtgggg agttatttca
    13921 gcgtcataaa tttcaaaacc agctactaca ataatatctt ttagttgttt ttcccagacc
    13981 atttccattt cagagcgagg tagaaatata gtggcaacat tttcctctac cttgataact
    14041 tcagcttgaa tagcatagaa atcatacatg gatcgagtca gtctttcttg tgcaaattct
    14101 aatatacgat tccaaaattg tttttctttc aatcctttct cctcctttac tatttaaaag
    14161 tttaatacta gagatatttt accatagata gcaagaattt tccacaagct gtgaaaaata
    14221 atccacaatg ttaccaaact ttatccacag gttggggata aaagaagaaa ttattgattt
    14281 attaagcttt ttatcgaaaa acatagtgga taaccttgtg agataaaaaa ataaaagaac
    14341 agccttattt caggctgttg ataattctac tatattcttc ttgatttgaa aaagaaataa
    14401 tgatttttcc actgtctttt ttagatagtt taatttctac atctaatccg agtagttttc
    14461 ttaactgttt ttcttcattt tgtatgaaat gattagtttt ttgctgtttc ttttgttttt
    14521 tctctgtcag aagagcttct aatttcctta cagaaatatc ttcttctata atccgttgaa
    14581 agaaatagtc ttgttgttcc ttatttaacc caactaggga acgcgcatgg gcttgtgata
    14641 gtttgccatt ttctacttct gaaagaatct gttctggcaa ggaaagtaaa cgaatggagt
    14701 tgctgatata tggacgagac ttgcccatct tatctgcaat ttcagcatgg gtgaatcctt
    14761 tctctacgag agattcatag gcgcgtgctt cttctattgg gtttaaattt tctctctgta
    14821 aattttcaat aatggactgg accatcatct cttggtctga aatctgttta acaacagctg
    14881 ggatagaccg tagaccagct aaaagtgaag cccgatagcg tctctctcct gcaaggattt
    14941 cataaccaat aacaggagat tgacgaacaa taatcggttg aatgacccca ttttctttga
    15001 tagactgtgc tagttcatct agtttttctc tatcaaattc ttttcggggt tgatagggat
    15061 ttttttgtat atctgtgata gaaatcattt caaatttttc catgattcta cactaacaca
    15121 tcttttctct tatgtaaagc tttctttaca tagatgtcaa ttaagattct aaatcacctg
    15181 aactcttgtt aagtttgata gaggtagttt cttctttccc gttacgatag taggttatct
    15241 taatggtgtc tccgatagaa tggttgtaaa gagcactttg taagtctgtt gatgaagcaa
    15301 tctctttgtc atctactttt gtaattacat cgtatttttc aaggtgacca ttggcaggca
    15361 tattactttg taccgaacga acaattacac cagatgtaac attacttgga atattgagtc
    15421 ttctgatgtc gcttgtactc acattagata aattaaccat ctggattccc aaagctggac
    15481 gcgtcacttt tccgtttttt tctaactgtt caataatatt gatagcatca tttgcaggaa
    15541 ttgcgaaacc aagaccttct acagatgttc ctccatttgt agcaatttta cttgaggtaa
    15601 ttccgataac ctgcccttga atattgatca gtgggccgcc agagttacct gggttaatag
    15661 cagtatcagt ttggatggct tttgtagaaa tagcttgtcc atcttccgat tttaaggata
    15721 catttctatt gagactggat acgatacctt gagtgacagt atttgcatat tcagaaccta
    15781 acgggctacc gatggcaata gcagtttctc ctacagttaa cttactagaa tcaccaaact
    15841 cagctactgt tgtcactttt tctgaagaga ttttgacgac agcaatatca gagaaagtgt
    15901 cagctccgac aatttttcca ggtactttag tcccatctga caatcgaata tctactttgc
    15961 tggcgccatt tataacgtga ttgttggtga cgatgtaagc ttctttatca ttctttttat
    16021 aaataactcc agatccttca ctagagattc gctgagaatc tgtgtcagta tcatcattgc
    16081 caaatacgct attttgtctg tttgccgaat aagtaataac agaaacaaca gcatctttta
    16141 ctttgttaac agcctgtgtt gttgaatttt cgttcttata ggcagtttgt gtaatagtac
    16201 tattgttgtt agagttgttt acactacttt tttgagttag ttgagttatt gaaaaactac
    16261 ccaaggctcc actaaaaaag ctaatgacga taacgactaa taattgaaac cattttttgt
    16321 aaaatgtttt tagatgtttc atatttgcct ccatatgttt gaattactga aagtataaac
    16381 tgactagctt aattataact taaacacaaa agttttacac aaactgtgga taactctttt
    16441 gaaattgtga ttttcttaat tgaaatctat tttttatttt gtgaataaga tgtgaaaaaa
    16501 tagagaatat gttagaatag agtcatgaaa attaaagttg taacagttgg gaaactgaaa
    16561 gaaaagtatt taaaagatgg tatcgcagag tattcaaaac gaatttctag atttgctaag
    16621 tttgaaatga ttgagttatc agatgaaaaa acaccagata aggccagtga atcagaaaat
    16681 caaaagattt tagaaataga aggtcagaga attttatcaa aaattgctga ccgtgatttc
    16741 gttattgtgt tagccattga agggaaaact ttcttctcag aagaatttag taagcagtta
    16801 gaagaaactt ctataaaagg attttctact cttactttta ttattggggg aagtttagga
    16861 ttgtcatcat ctgtaaaaaa tagagccaat ctttctgtca gttttggtcg cctaacctta
    16921 ccccatcagt taatgagact agttcttgtt gaacaaatct atcgcgcttt tacgattcag
    16981 cagggattcc cctaccataa atagaaaatt gacttttaat tgaatttttg gtagaataat
    17041 tgtattaggt ctcatagctc agctggatag agcattcgcc ttctaagcga acggtcgcag
    17101 gttcgaatcc tgctgggatc aatataatag caaagctggg aattttcccg gcttttttct
    17161 taaaaaagta cactttggga gaaaaaaatg acagttgaga gaattttatc taaaacgaaa
    17221 ttccattttg tataatggtt tttgtaagtt agcttacaag aaaaaacatt ttaggagatt
    17281 ttattatgaa aaacacagtt aaattggaac agtttgtagc tttgaaggaa aaagacttac
    17341 aaaagattaa aggtggggag atgaggttgt caaaattctt ccgtgatttt attttacaaa
    17401 gaaaaaagta atgaaataag gggaaagagt aatggattta tttggatttg ggacggttat
    17461 tgttcatttt ttaattatta gtcacagtta ccattttatt tgtaaaggtc aaataaatag
    17521 aaaagaatta ttcgtttttg gtgcttatac attactaaca gaaatagtat ttgattttcc
    17581 cttatatatt ctatatttag atgggttagg gattgaaaga tttttatttc ctttgggatt
    17641 atattcctat tttcgatgga tgaaacagta tgagagggat agaggactat tcctaagttt
    17701 actactatct cttttatatg agagcactca taactttctg tccgtaactt tctcctctat
    17761 aacaggagat aattttgttt tacaatatca tttcccattc tttttcgttg tgacggtgtt
    17821 aacctatttt gttacattaa aaatcattta ctatttccat ttggaactag cctattttga
    17881 tgaggactac ctttatcctt tcttgaaaaa agtatttttt gctttactat tgctacatat
    17941 tgtatctttc gtttcagata tggtaagtac gattaaacat ttgaatagtt ttggaagtat
    18001 tttgtcatct attgtcttta tctctctcct tttgaccttc tttgcaatga attctcataa
    18061 agttcaaatg gagaaagaga ttgctttgaa gcagaagaaa tttgaacaga aacatttaca
    18121 gaattacaca gatgaaattg ttggtctgta taatgaaatc cgtggttttc gacatgatta
    18181 tgctggaatg cttgtcagca tgcagatggc aattgacagt ggtaatttac aggaaattga
    18241 cagaatttac aatgaagttt tagtcaaagc aaatcataaa ttgcgttcag ataagtacac
    18301 ttactttgat ttgaacaaca tagaagactc agctttacga agtttggttg ctcagtcaat
    18361 tgtctatgct cgaaataatg gtgtagagtt tacactggaa gtaaaagata cgattaccaa
    18421 gcttccaatt gaactattgg atttggttcg tatcatgagc gttttattga ataatgctgt
    18481 cgaaggatcg gctgatagct ataaaaagca gatggaagta gcagttatta agatggaaac
    18541 tgaaacagtt attgtgattc agaattcatg taaaatgacg atgactcctt caggagatct
    18601 atttgcctta ggattctcca ctaagggaag aaatcgcgga gtcggattaa ataatgtgaa
    18661 agaactacta gataagtaca acaatattat tttagaaaca gagatggaag gcagtacatt
    18721 tagacaaatc attagattta agagggaatt tgaatgaaag ttttaatttt agaagatgtt
    18781 attgaacatc aagtgagact agagagaata ttggatgaaa tttcgaaaga atcgaatatt
    18841 ccaatatcat acaagacaac gggaaaagtc cgtgaatttg aagaatacat tgaaaatgat
    18901 gaagtaaatc agctttattt cctagatatc gatattcatg gaattgagaa aaagggattt
    18961 gaagtggctc agctcattcg tcattacaat ccttacgcta ttatcgtctt tatcactagt
    19021 cgatcagagt ttgcgactct aacatataaa taccaggtat cagccctaga ttttgttgat
    19081 aaggatatca atgatgagat gtttaagaag agaattgagc aaaatatctt ctacacgaag
    19141 agtatgttac ttgaaaatga agatgttgta gattatttcg actacaatta caagggaaat
    19201 gatttaaaaa ttccttacca tgatattttg tatattgaaa caacaggggt atctcataaa
    19261 ttgcgcatta ttggtaagaa ttttgcaaaa gagttttatg gtaccatgac agatattcag
    19321 gaaaaggaca aacatactca gcgattttat tctcctcaca agtcattttt ggtaaatata
    19381 ggcaatatca gagaaattga tcgaaaaaac ttagaaattg ttttctatga agaccatcgt
    19441 tgtcctattt caagattaaa aattagaaaa ttaaaagata ttttagagaa aaaatctcaa
    19501 aagtgattga caattagcaa gaaattgata taatggttat atctgctaca gatagaaggt
    19561 ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt tcgaatcccg
    19621 tacggactat tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat
    19681 gtcgtaggtt cgagtcctac tggcggagta tagataaaag ggaacacagc tgtgttcctc
    19741 tttttgtatc aatttgtatc accaagcatt ttcataagga agtctgttat ttcttgagaa
    19801 ctttcttttt ttccatgtgc aatccaagtt tggcagacac caaaaagtgc atgagttaga
    19861 tagatgctac tatattctaa ttcggtggta tttagattca gttgcataaa tcgcttttgt
    19921 aaatctgtac taagcatgat atgaagttta tttcgtaaga aattttggat ttctttagtc
    19981 ccattttcag aaagaagggc agccagaagt ggttctgact ctagatattc aaaaacttct
    20041 aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa tatattcaaa tgtatggaat
    20101 agcttgcttt gatagtgctc aatcatatca tacttatcct tatagtgagt atagaagctg
    20161 gaacgactaa ttccggcttt ttctactaat ttgacagtag aaattttatc aaatggctgt
    20221 tccatcagta attgtaccat agcattttca atagttcgct ttgtttttaa gcgtttgtta
    20281 ctttcttgca tatttcctcc ttgtaaacaa attagactat atgtctaaaa atagattttt
    20341 tatcttgtaa tttagatttt ttaatgtata atctattata tcaaaatttt agacaatatg
    20401 tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa tttaaaaaaa accaaccttt
    20461 attattgtca tgatcgggat ttctcttatt ccagatctgt acaatatcat atttttgtca
    20521 tcaatgtggg atccatatgg gcaattgtct gacttacctg tggcagttgt aaataatgat
    20581 aaagaggctt cctataatgg taatactatg gcaataggaa aagacatggt gtccaattta
    20641 aaagaaaata aaaccttgga ttttcatttt gtagatgaag aggaaggaaa gaagggattg
    20701 gaagatggcg attactatat ggtagtgact ttaccaagtg atttatctga aaaaacaact
    20761 acattatcca atattcaatc gacagcagct tatcaatcat tgacaagtga gcaacaaact
    20821 gagataagtg attctgtatc tcaaaattca actgatagta ttcaatcggc tcagtcaatt
    20881 gtagctttag tacaagattt acagggaagt ttagaaaact tacaaaatca atcttctaat
    20941 ctttcgactt taaaaaatca atctaatcaa gtatcaccta ttacttctac ttctttgata
    21001 ggattgtcaa gtggattaac agagatacaa ggagatgtta ctagcaaatt agttcctgcc
    21061 agtcagtcga ttgcatcagg tgtaaacgca tatactacag gtgttgataa agtttctcag
    21121 ggcgcaagtc aactaagtga aaaaaatgcc accttgacag gtagtttgga taaactagtt
    21181 tcaggctcaa acaccttgac acaaaaatct tctagattga cagcaggagt tggttaatta
    21241 caatcaggat ctgggcaatt agcagacaaa tccagtcagt tactttcagg tgcttctcca
    21301 ttagagaata gagctaataa attggcagat ggatctagga aactagcaga aggtggaaca
    21361 aagttaactt ctggattgga agatttacag acaggacttg cttctttagg acaaggacta
    21421 ggtaatgcta gtgatcaact caaatcagta tcaacagaat ctaaaaatgc agagattttg
    21481 tcaaatccac tcaatctttc aaaaacagac aatgatcaag ttcctgtaaa tggaatcgca
    21541 atagctcctt atatgatatc agttgctctt ttttttgcag caatatcaac aaatatgata
    21601 tttgcgaaat tgccttcagg acgtcatcca gagagccgtt gggcttggtt gaaatcttga
    21661 gctgaaataa atggtattat agctgttttg gcaggaattt tggtatatgg aggagttcag
    21721 cttattggtt taactgctaa tcatgagatg agaatattta ttctcatcat cctaacaagt
    21781 ttagtattca tgtctatggt gaccacttta gcaacgtgga atagccgtat aggagctttt
    21841 ttctcactta ttttgctttt actacagtta gcatcaagtg caggtactta tccacttgct
    21901 ttgacaaatg atttctttag atctattaat ccctggttac caatgagcta ttcagtttcg
    21961 ggattacgac aaacaatctc tatcaacaag tcattttcct agctgtcata ctagctctat
    22021 ttactggttt aggtatgcta gcctatcaac ataagaaaat ggaagaagat taaaaaaatc
    22081 gaccgattaa ctggtcgatt ttttatgcct tagatgactt tcgtctgtga ttatagattc
    22141 caaatagtaa gagagaagta aaggaacaga ttgctccagt aataaaacca ttgggaatga
    22201 aggaaagtgt aatagttcct ttccccttgg gaatgtcaac tttcataaat ccagtttgag
    22261 cttgtttaat ttctattttc ttaccatctt ggtaggcaga ccaacctttg tcataaggaa
    22321 tggtgaagaa aatagatgta tcttgttgga catcatatgt agcaaaaacc ttgtttttag
    22381 aagttgatac tgtgacaggt tgttctttaa ttttttgaat tgcctcggtg aaagttttgg
    22441 tatctaaacg atagaaggta ggagattcaa atgatacttg tgaatttcca gggaaactaa
    22501 cattgatatt gaaagttttt ttctctttag tatatcctag attaaagaag gagaagacat
    22561 tatcagttgt aaaagtcttt ttttcaccat ttacaaggat gtcaaccttc ttttgtttat
    22621 cgttagaaaa gtgaaggttt atgaaagaga gataaacttg gctgttttct ggaacttcaa
    22681 tttgatactg gattgctgca tcttcatttg aagaacttgt gacactaatc aaatcattag
    22741 tattttctat tttttctgtt ttttcataag gtattggaga aaaataatca aaattgacgt
    22801 tagcaagttg atttaaaaat gaggcctgat tatccaaggt atgttcattg aacttgacat
    22861 cattgtaaac agattgacta gcaactgcaa tcggaagaga gtattgattt tcatataggg
    22921 taagattatc tttttgatag atatctttaa agccatactt atcaatagga ctgtctgaga
    22981 tattgtactg gataccaaat aaactatcag ccaaaatact attatttgca tatcggagat
    23041 tgagattagt cccagaggat ttaaaaccaa gtttatctaa agtagagctt gatgaacgat
    23101 ttcgaacaga tgaaaattga gagattccat tgtagttgaa tttcatactg tcatttcctg
    23161 tctgagtttg tagtttttca gtacgagtaa attgatttcc aatatatgtt gagaaagatt
    23221 ccatagctag gatatctcga ctataagcac ttcgagaagc aaatccccat tccttagcaa
    23281 ttccgtccat ttgagatgaa gcatttaaac tcatttcaac cagtataaat aaagagatta
    23341 gaatggcaaa tagattcaca gatataaact ttttgataac tgcaaggagt aaaagagaat
    23401 agacaaccaa aaattcaaga gtaaacagaa tattcaaatc tgttaaaaaa gaataatgcg
    23461 attttagata gatggtagct aaaaatcctg ctactacaag aaaaagcgaa actaaaaaat
    23521 tccagacttt aagttctttc agacgcttta agacttctgc tgctgtgtaa attaacaagg
    23581 tagagaaaat ccaagcatag cgatgtaaaa acatgtttgg agtatgcatg ccttgccaaa
    23641 ataagtcaag agcttctatg taaaagcttg caattagaaa tgcaaagaat attacatata
    23701 tgagtttcac gtgaaactta atagatttca gcgtaaaaaa taaaatggtc aaaataaagg
    23761 gaaatagtcc aacaaaaatc attgggatgg ccccatactt tgttgtgtca aaggaaccaa
    23821 tgaattgctt agcaaagaga tcaagatacc agctactttc agtttgaaac tttgtaactt
    23881 cagtcaattt ttccccatgt gtctgtaaat caaatagagt gggaagagtc ataatcaaac
    23941 tagccatacc agctaaaaag gagataacta tgaaatcaag aacagatgat tttcgagtct
    24001 taaagtccca cgaaatttga cagagatacc agaaaataag aaacaatact gtcatatatc
    24061 caaaataata attttgaata aataagattg acagacttgt aaagtacaat aggagtttct
    24121 tttcagttat cagtagatgt aaaccagtta taattaaagg aatcaagata aaaacatcta
    24181 gccaggtttt tatctctaat tgactgacag tgaaactcat cagagcatag gaagtagata
    24241 aggctagttt taaagtctga gggatagatt gaaacaattt attcaaacta aaaaaggttg
    24301 acagaccaat caatccaaat tttaagagag tggtcagata gacagcatct ggcatgttcg
    24361 ttagatcaaa aaagtaaact agaggcgcga gaaaactacc caagtaataa ctagataggg
    24421 catagaagtt tagccctaga ccacttgtaa aggtgtaaaa cagactacta tttccatgta
    24481 ggatatttcg taaggctaca tcaaaaataa cgtattgatg aaagccatct cctaatagag
    24541 gagagttgtc gctattccag tagatacctt gagatagata tactccagac ataatcacta
    24601 caggaatgat gagagaaata aaataggttc gatatgtttt taaaaatgat ttcatgttac
    24661 ctcgtagaat gatagaaaac tcagttggtt aacccaactg agttttgaag ttttatttag
    24721 tctttccaaa gttctttaac ttttgcttgt acttctgcat tttctaggaa ttcatcgtag
    24781 gtttcatcga tacggtcaat gacgccattt ttagataaga caatgatatg gttagccaaa
    24841 gtttgaataa attcgtggtc atggctagca aagatgattg attctttaaa gtttttcaat
    24901 ccatcattca agcttgagat agattccaag tccaagtgat ttgttggatc atcaagtaca
    24961 aggacatttg attttaagag catgagtttt gaaagcatga cacgaacttt ttctccccct
    25021 gacaagacat ttacaggttt gttaacttca tctccagaga agagcatacg gccgaggaag
    25081 ccacgtagga aagtattgtc atcttcttct ttacttgcga attgacgcaa ccagtcaaga
    25141 attgattctc ctcctgcaaa atcagctgag ttatcttttg gtaggtaaga ttgactagtt
    25201 gtaactcccc acttgacagt tccttcatag tcaatatctc ccatgattgc acgaattaat
    25261 gcagtcgttt gaatatcatt ttgtccaata agtgctgtct tatcatctgg acgcaagatg
    25321 aaactaatat tatccaagat agtttcacca tcaatcttta cagttagatt ttctactgtc
    25381 aagagatcat taccaatctc acgttccgct ttaaagttga taaatggata tttacgacta
    25441 gatggtacaa tctcttctag ctcaatctta tcaagcattt tcttacgtga tgttgcctgc
    25501 cttgacttag aagcattggc agagaaacga gcaacgaatt cttgcaattg tttaattttt
    25561 tcttctgctt tagcattacg gtctgctagc aatttagcag caagctcaga agattccttc
    25621 cagaagtcgt agtttccgac atagagtttg atttttccaa agtcaaggtc ggccatgtga
    25681 gtacaaactt tgtttaagaa gtgacggtcg tgggatacta cgataactgt gttatcaaag
    25741 tcaatcaaga agtcttctaa ccaagtaatc gattggatat ccaaaccgtt agtaggctcg
    25801 tccaagagaa gaacatctgg tttaccaaaa agtgctttgg cgaggagaac ctttactttt
    25861 tcaccgttgg ccaattcgct catgttttgg tagtgtaatt cttctggaat gtttaggttt
    25921 tgaagtagtt gagaggcttc actctctgct tcccaacctc caagttcggc aaactctcct
    25981 tcgagttcgg cagcacgaac cccgtcctcg tctgagaaat cttccttcat gtagatagca
    26041 tctttctctt tcatgatgct ataaagtttt tcatttccca tgataacgac atcaatggca
    26101 cgttcatctt cgtagtcaaa gtgattttga cgaagaacag agagacgttc atctggacca
    26161 agagagatgt gaccagtagt aggttcgata tctccagcta aaatttttaa aaaggttgat
    26221 tttccggcac cattagcacc gattaatccg taagtatttc cttctgtaaa tttgatattg
    26281 acatcatcaa aaagtttgcg atcactaaaa cgtagtgaaa catcagatac tgtaagcaat
    26341 atttttctcc tatatgtgta atatatttat tctactagaa aatacagaaa tattcaaatt
    26401 tttatttgtc aattttgtgt aaattatatt tacagtatcc tttacacaaa tctgtaaaaa
    26461 gcaaggctga tttattttga taaattacgg ttatttcatt aaaaaaatgc tataattgaa
    26521 aggactatat cgaaggagaa caaaatgact aaacccatta ttttaacagg agaccgtcca
    26581 acaggaaaat tgcatattgg acattatgtt ggaagtctca aaaatcgagt attattacag
    26641 gaagaggata agtatgatat gtttgtgttc ttggctgacc aacaagcctt gacagatcat
    26701 gccaaagatc ctcaaaccat tgtagagtct atcggaaatg tggctttgga ttatcttgca
    26761 gttggattgg atccaaataa gtcaactatt tttattcaaa gccagattcc agagttggct
    26821 gagttgtcta tgtattatat gaatctagtt tcgttagcac gtttggagcg aaatccaaca
    26881 gtcaagacag agatttctca gaaaggattt ggagaaagca ttccgacagg attcttggtc
    26941 tatccaatcg ctcaagcagc tgatatcaca gctttcaagg ctaattatgt tcctgttggg
    27001 acagatcaga aaccaatgat tgagcaaact cgtgaaattg ttcgttcttt taacaatgca
    27061 tataactgtg atgtcttggt agagccggaa ggtatttatc cagaaaatga gagagcaggg
    27121 cgtttgcctg gtttagatgg aaatgctaaa atgtctaaat cactaaataa tggtatttat
    27181 ttagctgatg atgcggatac tttgcgtaaa aaagtaatga gtatgtatac agatccagat
    27241 catatccgcg ttgaggatcc aggtaagatt gagggaaata tggttttcca ttatctagat
    27301 gtttttggtc gtccagaaga tgctcaagaa attgctgata tgaaagaacg ttatcaacga
    27361 ggtggtcttg gtgatgtgaa gaccaagcgt tatctacttg aaatattaga acgtgaactg
    27421 ggtcctattc gtgagcgccg tattgaattt gctaaggata tgggagaagt ttataatatg
    27481 attcaaaaag gtagtgaaag agcgcgtgaa gttgcgggtc aaaccctatc tgaggtaaaa
    27541 ggggcaatgg gacttcatta ctttaactaa gtttatttta caagaaacta tcatttctat
    27601 ctcgaagaaa agatagtttt ttatttaccc ctgtaacatt tgacaaattt ttatagaatg
    27661 gtatgataga tacaatataa aaagagtcaa gctcaaaaag aaagaaaaga ggaaacttcg
    27721 aatgtctaat tgggacacta aatttttgaa aaaaggtttt acctttgatg atgtattgct
    27781 tattccagct gaaagtcatg tgttgcctaa cgatgcagat ttaacaacta aattggcaga
    27841 taatttgact ttaaatatcc caattattac cgctgccatg gacacagtta cagagagtca
    27901 aatggccatt gctattgctc gtgcaggtgg tctcggagtt atccataaaa acatgtcaat
    27961 tgctcaacaa gcagacgagg ttcgtaaggt aaaacgttct gaaaatggag ttattattga
    28021 tccgttcttc ttgacgcctg aacatacaat tgctgaagca gatgagctta tgggtcgtta
    28081 ccgcatcagt ggtgttccag ttgttgaaac acttgaaaat cgtaaattgg ttggtatttt
    28141 gacaaaccga gatcttcgtt ttatttcaga ttataatcaa ccaatttcaa accatatgac
    28201 tagtgaaaat cttgttactg ctcctgtggg tacggatctt gcaacggctg agagtattct
    28261 tcaagagcat cgtattgaaa aacttccgtt ggtcgatgaa gaaggcagtc tttctggttt
    28321 gatcactatc aaagatattg aaaaagttat tgagtttcca aatgcggcta aagatgaatt
    28381 tggtcgtctt ctagttgcag gtgcagtagg tgttacttca gatacatttg aacgtgcaga
    28441 ggctcttttt gaggcaggag cggatgcgat tgttattgat actgcacatg gtcattctgc
    28501 aggtgtcttg cgtaaaattg ccgagattcg tgctcatttc ccagatcgga ctttgattgc
    28561 tggaaatatt gctactgctg aaggtgcacg tgccctttat gaagcgggtg tagacgttgt
    28621 taaggttggt attggaccag gttctatctg tactactcgt gtgattgctg gtgttggtgt
    28681 tccgcaagta acagctatct acgatgctgc agctgttgcg cgcgaatatg gtaaaacgat
    28741 tattgctgac ggtgggatca agtattctgg agatattgta aaagcacttg ctgcaggtgg
    28801 aaatgctgtt atgcttggat ctatgtttgc tggaactgat gaagctccag gcgaaactga
    28861 aatcttccaa ggacgtaaat tcaagactta ccgtggtatg ggatcaattg ctgctatgaa
    28921 gaaaggttca agcgaccgtt atttccaagg ttctgtcaat gaagcaaaca agctcgttcc
    28981 agaaggaatt gaaggtcgtg ttgcttataa aggagcggca gctgatattg ttttccaaat
    29041 gattggtggt attcgctctg gtatgggtta ctgtggtgca gctaacctta aagaactaca
    29101 cgataatgct caatttattg aaatgtctgg tgctggtttg aaagaaagcc atcctcatga
    29161 tgtgcaaatt actaatgagg caccaaatta ttctatgtaa aaaacaatga aaagaactcc
    29221 agtgaaaaca ggagttcttt tacaatgttg tcaatttcca tttacagaag ctttaccatc
    29281 ctgaatagtg aagatactta gattttctgg cagattttga agatggtcta agcttgttgt
    29341 tgtgataaag gtttggattg attgagaaat cgtttctaat aattttaact gtctagtgtt
    29401 gtcaagttca ctcatcacat cgtcaagcag taatatagga gattctgtgg taatgctttc
    29461 cattaattcg atttctgcta attttatcga gaggacgaga ctacgatgtt gaccttggct
    29521 tccgaaacta gcatccatcc catttatata aaaagaaatg tcatctcgat gaggaccgac
    29581 accagtattc tttttaaata aatctctgga tctacttttt tctaaagcaa ttttgaaaga
    29641 ttcggataag ttttgtttgt cagttatatt gacagaagat tgataggata ttgacaactc
    29701 ttcgatctga ttagagagtt caaaatgttt cttacgccca aatgattcta gtttttttat
    29761 gaaatctaag cggtgattca ttacacgaca tccataatca actagctgat catctaacac
    29821 agaaaggaat gtttcatcta ttttttgagc tgattttagg taagtgtttc tttgctttag
    29881 gatgtggtta taattggtta agtcagataa atagattggc ttaatttgcc caagttccat
    29941 atcaatgaat tttcgtcgaa tcgaaggtgc tcctttaatt agttgtaaat cttcaggagc
    30001 aaataagaca acattcatgt gtcctacata atctgaaagg cgtgcctgtt ttaagtgatt
    30061 aacttttgtt acacggcctt tttgtgttag ttcgatttct aggggaatgg atccagtttt
    30121 tttctgaacg agacctgaaa gatgaagttg ttcctcatca aaatgaatga gatttttatc
    30181 tgttcgagtt cgatgactac gcgttaaggc taaaaaatag atagcctcta acatgtttgt
    30241 ttttccttgt gcattacgtc ccaaaaagac attcaattta ggattaaagt ctattttcgt
    30301 ttctttgtaa ttacgaaaag tcttgagaga tagatgttgt agccacatga ttatctacca
    30361 gggaatcgtg gagcttgttg gcttttaggt gatgaagcag gtttcgattt gtctttttta
    30421 actcccttat tcatcttttt gacaagttta gcgatccgtt ctttttcaac tttatcagct
    30481 tggtattcat cttgttcttc agaagtaggt tgtgtcaaca agatgtcaat gttcatgtca
    30541 gggatgtcaa ctttatcgcc aatacgaagt ttttttccac gacgactctc taattcccta
    30601 ttaaagtaaa cagaatgttc agagagaaat gatttaatag ctcctccgct atgtgtaatt
    30661 ccaagttctt tgagtagtgc ttggagggta ataaattctt caaataattt gtattccata
    30721 attcacctca atctttggta ttataccata ttttcctaaa aatagtgaga gagacagcga
    30781 gaaatgtaag cgatttttat ttcaaaagtg ttacagggaa caagaaaatt tcaggttttc
    30841 gtgatataat agaagtctgt atataaggag gtaaatcatg gagttagtgc atggaatttc
    30901 aacacatttt atccaatcaa aaaagtttaa aacaaacaaa attaccgtgc gttttaccgc
    30961 tccattatcc cttgatacga ttgcaggtca catgttgagt gcaagtatgc tagagactgc
    31021 taatcagatg taccccactt ctcaagattt gaggagacac ttggccagtc tatacggtac
    31081 agatatgtca accaattgtt tcagaagagg gcaaagccac attatagaat tgacatttac
    31141 ctatgttcgt gatgagtttt taagtaggaa aaacgtgcta acctctcaga ttttggaact
    31201 tgtaaaagaa actctttttt cacccgcagt agttgataat gggtttgatc cggccttatt
    31261 tgaaattgag aaaaaacaat tgctagcaag tttagcagct gatatggatg attcttttta
    31321 ttttgcacat aaagaattgg ataaattgtt ttttcatgat gaacgtcttc aattggaata
    31381 tagtgattta cgaaatcgta ttttagctga aactccacaa agttcttatt cttgtttcca
    31441 agaattttta gccaatgatc gaatagattt ctttttccta ggtgatttta atgaggttga
    31501 aattcaaaat gtattagaat catttggctt taaaggtcga aaaggagatg tgaaggttca
    31561 gtattgtcaa ccttattcta atatccttca ggaaggtatg gttcggaaaa atgtgggaca
    31621 atccattttg gaattaggtt atcattaccg ttctaaatat ggtgatgagc aacatttacc
    31681 catgattgta atgaatggtt tacttggtgg atttgctcac tctaagctct ttacaaatgt
    31741 ccgtgaaaat gctggattag cttataccat ttcaagtgag cttgatttat ttagtggatt
    31801 cttgaggatg tatgctggta tcaatcgaga aaatcgtaac caggctcgta aaatgatgaa
    31861 taatcaactg cttgatttaa aaaaaggtta ttttacagag tttgagttaa atcagaccaa
    31921 ggaaatgatt cgttggtcgt tgttactttc tcaagataat caatcttcat tgattgaacg
    31981 tgcttatcaa aatgccttat ttggaaaatc ttcagcagac tttaaaagtt ggattgcaga
    32041 gcttgaacaa attgacaaag atgctatttg tagagtagct aataatgtga aactacaagc
    32101 gatttacttt atggaaggaa tagaatgaca aaggttgttt ttgaagaaaa atactatcca
    32161 gctgtaaaag aaaaggttta tcgaactcgt ttggccaacg gattgacagt tgctcttttg
    32221 cctaaaaagg aatttaaaga ggtttacggg agtgtcactg tacagtttgg ttcggtagat
    32281 acgtttgtca cagaagttga cggatatgta aaacaatatc ctggaggaat tgctcatttt
    32341 cttgaacata aattatttga gagagaagat tctagtgatt tgatgtcggc ttttacgagt
    32401 ctaggtgcag atagtaatgc ctttacaagc tttacaaaaa caaactatct tttttcagca
    32461 acggattatt ttttagaaaa tttagattta cttgatgaat tggtaacatc agcacacttt
    32521 actgaagctt ccattctgac agagcaggat attattcagc aagaacgaga aatgtaccaa
    32581 gatgatccag attcgtgttt attcttttca actttagcga atttgtatcc tggtacacct
    32641 ttagcaactg atatagttgg aagtgaggag tccatttccc aaatcaatct aactaatttg
    32701 caagaaaatt ttacaaagtt ttacaaacct gtaaacatgt ctctgttttt agttggtaat
    32761 tttgatgtgg agcgagtaca ggactatttt gaaagcaaag aactgaaaga ttcagatttt
    32821 caggaagtag caagagaaaa gttgttttta cagcctgtaa agccaacaga tagtatgaga
    32881 atggaagtat cttctcccaa actagcgatt ggagttagag gtaagcgaga agtttctgaa
    32941 gcggattgct atcgacatca tattttatta aaattattgt ttgcaatgat gtttggttgg
    33001 acttcggatc gttttcaaaa atgttatgaa tcaggtaaaa ttgatgcgtc cttatctctg
    33061 gaagttgaaa taacaagtcg ctttcatttt gtcatgttga caatagatac gaaagagcca
    33121 gttgctttgt ctcatcaatt taggaaggct attcgtaatt ttacaaagga tttagatatt
    33181 acagaggaac atttagatat tatcaaaaga gagatgtttg gcgaattttt cagtagcatg
    33241 aactctcttg aatttattgc aacgcaatat gatgcttttg aaaatggtga gacaattttt
    33301 gatttgccga aaattttaca ggaaattact ttagaggatg tccttgatgc tggacatcat
    33361 ttaatagatg atggtgacat agttgatttt acaatattcc catcgtagta acctatcata
    33421 atagacacta gaaagaaggg atgacaagta tgagaaaaaa aacaattgga gaggttttac
    33481 gattagctag aatcaatcag ggattgagtt tagatgaatt gcagaaaaag acagaaatcc
    33541 agttagatat gttggaagca atggaagcag acgatttcga tcaacttcca agtccttttt
    33601 acacgcgttc tttcttgaaa aaatatgcat gggctgttga gttagatgac caaattgttt
    33661 tggatgctta tgattctggg agtatgatta cttatgagga agtagatgtt gatgaagatg
    33721 agttgacagg tcgtagacgt tcaagtaaga aaaagaagaa aaaaacatca tttttacctt
    33781 tattttattt tatccttttt gctttatcga ttttaatttt tgtgacttat tatgtttgga
    33841 actatattca aactcaacca gaggagcctt ctctttctaa ttacagtgtg gttcaatcaa
    33901 caagttcaac tagctctgtt ccccactcct caagtagtag ttcttctagt atagaatcag
    33961 ctataagtgt atcaggcgaa ggaaatcatg tagaaatcgc ttataagaca agtaaggaaa
    34021 cagttaaatt gcaattggca gtttcagatg ttacaagttg ggtcagtgtt tcagaaagcg
    34081 aacttgaggg cggtgtaacc ttatcgccaa agaagaaaag tgcagaagca acagttgcaa
    34141 ctaaaagtcc tgtaacaatt acgttaggtg ttgtaaaagg tgttgatttg acagtagata
    34201 atcagactgt tgatttatcg aaattaacag ctcagactgg acaaatcact gtaaccttta
    34261 ctaaaaatta aggaaaaacg aatgaaaaaa gaacaaattc ccaatctctt aacaataggt
    34321 cgaattctct ttatacctat ttttatcttt attttaacga taggaaattc gatagagagt
    34381 catatagttg cagctattat ctttgctgtt gccagtatta ccgactattt agatggatat
    34441 ttagctcgta aatggaatgt ggtcagtaat tttggtaaat ttgcagatcc tatggcggat
    34501 aagttactag ttatgtcggc ttttattatg ttgattgagt taggtatggc tccggcttgg
    34561 attgttgcag tgattatctg tcgtgagtta gctgtgacag gtttaaggct tttattggtt
    34621 gaaactggtg gaacaatttt agcagcagca atgcctggaa aaattaaaac ttttagtcag
    34681 atgtttgcta ttattttctt gctattacat tggactttgc ttggtcaagt tctactttat
    34741 gtagccttat ttttcactat ctactctggc tatgactatt tcaagggtag tgcctatgta
    34801 tttaaaggga catttggttc gaaatgaaat caataattga tgtaaaaaat ctttcttttc
    34861 gctataaaga aaatcagaac tactacgatg tgaaggatat tacgtttcac gtgaaacgtg
    34921 gagaatggct ttcgattgta gggcataatg gtagtggtaa atcaacgacg gttcgattaa
    34981 ttgatggctt actggaagca gaatccggag agattgtaat tgatggccaa cgtttgactg
    35041 aggaaaatgt ttggaatata cgtcgtcaaa tcggtatggt ttttcaaaat ccagacaatc
    35101 aatttgttgg agcgactgtt gaagatgatg ttgcttttgg tttggaaaat cagggacttt
    35161 ctcgtcaaga aatgaaaaag agagtggaag aagctctggc tttagttggc atgttggact
    35221 ttaaaaagag agagccagcg cgtctatcag gtggccaaaa gcaacgtgtg gccattgcag
    35281 gtgttgtagc cctaagacca gctattttaa tcttagatga agcaacgagt atgttggatc
    35341 ctgaggggcg tagagaactt attgggacag taaaaggaat tcgaaaagac tatgatatga
    35401 cggtcatttc tattacccat gatttggaag aagtcgccat gagtgatcgc gtattggtca
    35461 tgaaaaaagg ggaaattgaa tcaactagta gtccaaggga gcttttctct cgaaatgatt
    35521 tagatcaaat tggattagac gatccttttg ctaatcaatt aaaaaaatct ttgagccaga
    35581 atggctatga tttacctgaa aattatttga cagaaagtga gctagaggat aagctatggg
    35641 aattgctcta gaaaatgtga attttatata tcaagaaggt actcccttag cttcagcagc
    35701 tttgtcggat gtttctttga cgattgaaga tggctcttat acagctttaa ttgggcacac
    35761 aggtagtggt aaatcaacta ttttacaact cttaaatggt ttattggtgc caagtcaagg
    35821 gagtgtgagg gtttttgata ccttaatcac ctcgacttct aaaaataaag atattcgtca
    35881 aattagaaaa caggttggct tggtatttca gtttgctgaa aatcagattt ttgaagaaac
    35941 ggttttgaag gacgttgctt ttggaccgca aaattttgga gtttctgaag aagatgctgt
    36001 gaagactgcg cgtgagaaac tggctctggt tggaattgat gaatcacttt ttgatcgtag
    36061 tccgtttgag ctgtcagggg gacaaatgag acgtgttgcc attgcaggca tacttgccat
    36121 ggagccatct atattagtct tagatgagcc aacagctggt ctagatcctc tagggagaaa
    36181 agagttgatg accctgttca aaaaactcca ccagtcaggg atgaccatcg tcttggtaac
    36241 gcatttgatg gatgatgttg ctgaatatgc taatcaagtc tatgtaatgg aaaagggacg
    36301 tttagtaaag gggggcaaac caagtgatgt ctttcaagac gttgttttta tggaagaagt
    36361 tcagttggga gtacctaaaa ttacggcctt ttgtaaacga ttggctgata gaggcgtgtc
    36421 atttaaacga ttaccgatta agatagagga gttcaaggag tcgctaaatg gatagtatga
    36481 ttttggggcg ttatatccca ggggattcga ttgttcaccg attggatcca cgtagcaaat
    36541 tgcttgctat gatgctactg attttgattg tgttttgggc taataacccc ttgacgaatc
    36601 tgattctttt tatagcgaca gggatattta ttgccttgtc aggagtatct ctttcatttt
    36661 ttattcaggg cttgaagtct atgtttttct tgattgcctt cacaactatt tttcaactat
    36721 ttttcatttc taatgggaat gttttatttg agttttcgtt tgtgagaatc acggattatg
    36781 ctttgcaaca agctgggatt attttttgtc gctttgtatt gattattttc ttttcaactt
    36841 tgttaacctt aacaaccatg cctttaagtt tggcatcagc tgtcgaagct ttattagcac
    36901 ctttaaagcg tgtgaaagtt ccagttcatg aaattggatt gatgctgtct atgagtttgc
    36961 gttttgtccc aaccttgatg gatgatacga ctcggattat gaatgcacag aaagctcgtg
    37021 gagtggattt tggagaagga agcatcgttc aaaaagtaaa ggcgatgatt cccattttga
    37081 ttcctctttt tgcgacaagt ttaaaacgtg cagattcctt ggctatcgct atggaagcgc
    37141 gtggctatca gggtggaaaa ggcagaagtc aataccgaca attgaaatgg actctaaagg
    37201 atacgctgac cattcttgtt attctcgtac ttggttgttg tttatttttc ttaaaatctt
    37261 agtagctttc aggaattgat aaaaagttac tgtaacagtt tttgatataa aggtagggat
    37321 atgaaccgtt ttaaaaaatc aaaatatgtc attattgttt ttgtcactgt tctgcttgtg
    37381 tcagctctct tagcgacgac ttattcaagt acaattgtga caaaattagg agatggaatc
    37441 tcattggttg atagagttgt acaaaaacct tttcagtggt ttgattctgt caaatcagat
    37501 ttggctcatt tgacacgaac atataatgaa aatgaaagtt tgaagaaaca gctttaccaa
    37561 ttagaagtta aatcaaatga ggtggaaagt ttaaagacag aaaatgaaca actgcgccaa
    37621 ttgcttgata tgaagtctaa attgcaagcc acaaagactt tagcagcaga tgttattatg
    37681 cgttctccgg tatcttggaa gcaggagttg accttagatg caggtagatc aaaaggtgct
    37741 tctgagaaca tgttagctat tgcaaatggt ggcttgattg ggagtgtttc aaaagtagag
    37801 gagaactcta ctatagtcaa ccttctgaca aatacggaaa atgctgataa gatttctgtt
    37861 aaaattcaac atggctctac tacaatttat ggaattatta ttggctatga caaggaaaat
    37921 gacgttctta aaattagcca attaaatagt aatagcgata ttagtgcggg agataaggtg
    37981 actactggtg gattaggaaa ctttaacgtt gctgatattc ctgttggtga agtggttgcc
    38041 acaacgcata gtacagacta tttgacacga gaagtaactg ttaaattgag tgcagatact
    38101 cataatgtag atgtgataga attagtgggg aattcataat gagacagttg aagcgagttg
    38161 gagtattttt attgcttcct ttctttgttc taattgacgc ccatattagc cagcttctgg
    38221 gctcattttt cccccatgta catttggcta gtcattttct ttttctattt ctcttatttg
    38281 agacgataga agtatcagag tatctctacc tagtctattg ttttgttata ggcttggttt
    38341 atgatgttta ctttttccat ctaataggga ttacaactct cttatttatc ttattgggag
    38401 ccttccttca taaattgaat agtgttattt tgttgaatcg ttggacaaga atgctagcta
    38461 tgattgtgct gacattcctg tttgaaatgg gtagttatct tttggctttt atggtagggt
    38521 tgacagtaga tagcatgtcg atttttatag tctatagctt ggtaccgacg atgattttaa
    38581 attttttatg gattactgtt tttcaattta tttttgaaaa atattatcta taagaacgac
    38641 atataaatgt aacaaaggcg taatatttat taggcctttt tttggtatac tagtattgtc
    38701 tttaaaagaa ggagtatcta cgtaatatga agaaaaaaat cttagcgtca cttttattaa
    38761 gtacagtaat ggtttctcaa gtagctgttt taacaactgc gcatgcagaa acgactgatg
    38821 acaaaattgc tgctcaagat aataaaatta gtaacttaac agcacaacaa caagaagccc
    38881 aaaaacaagt tgaccaaatt caggagcaag tatcagctat tcaagctgag cagtctaact
    38941 tgcaagctga aaatgataga ttacaagcag aatctaagaa actcgagggt gagattacag
    39001 aactttctaa aaacattgtt tctcgtaacc aatcgttgga aaaacaagct cgtagtgctc
    39061 aaacaaatgg agccgtaact agctatatca ataccattgt aaactcaaaa tcaattacag
    39121 aagctatttc acgtgttgct gcaatgagtg aaatcgtatc tgcaaacaac aaaatgttag
    39181 aacaacaaaa ggcagataaa aaagctattt ctgaaaaaca agtagcaaat aatgatgcta
    39241 tcaatactgt aattgctaat caacaaaaat tggctgatga tgctcaagca ttgactacga
    39301 aacaggcaga actaaaagct gctgaattaa gtcttgctgc tgagaaagcg acagctgaag
    39361 gggaaaaagc aagtctatta gagcaaaaag cagcagctga ggcagaggct cgtgcagctg
    39421 cggtagcaga agcagcttat aaagaaaaac gagctagcca acaacaatca gtacttgctt
    39481 cagcaaacac taacttaaca gctcaagtgc aagcagtatc tgaatctgca gcagcacctg
    39541 tccgtgcaaa agttcgtcca acatacagta caaacgcttc aagttatcca attggagaat
    39601 gtacatgggg agtaaaaaca ttggcacctt gggctggaga ctactggggt aatggagcac
    39661 agtgggctac aagtgcagca gcagcaggtt tccgtacagg ttcaacacct caagttggag
    39721 caattgcatg ttggaatgat ggtggatatg gtcacgtagc ggttgttaca gctgttgaat
    39781 caacaacacg tatccaagta tcagaatcaa attatgcagg taatcgtaca attggaaatc
    39841 accgtggatg gttcaatcca acaacaactt ctgaaggttt tgttacatat atttatgcag
    39901 attaatttac agagggactc gaatagagcc ctcttttcag gttttaccgt gacaatccct
    39961 attaaaaatt atatcaaaat agcttgaaaa tattggaaaa gtatggtaga atgaaaattg
    40021 tcgtgtgaac gataatactc attcttgatg aattgtgaag cagttgccct tgggtcgttt
    40081 tgcgagttga agtcaagaag aggaaaaaaa caaaaaggag aaatactcat ggcagtaatt
    40141 tcaatgaaac aacttcttga ggctggtgta cactttggtc accaaactcg tcgctggaat
    40201 cctaagatgg ctaagtacat ctttactgaa cgtaacggaa tccacgttat cgacttgcaa
    40261 caaactgtaa aatacgctga ccaagcatac gacttcatgc gtgatgcagc agctaacgat
    40321 gcagttgtat tgttcgttgg tactaagaaa caagcagctg atgcagttgc tgaagaagca
    40381 gtacgttcag gtcaatactt catcaaccac cgttggttgg gtggaactct tacaaactgg
    40441 ggaacaatcc aaaaacgtat cgctcgtttg aaagaaatta aacgtatgga agaagatgga
    40501 actttcgaag ttcttcctaa gaaagaagtt gcacttctta acaaacaacg tgcgcgtctt
    40561 gaaaaattct tgggcggtat cgaagatatg cctcgtatcc cagatgtgat gtacgtagtt
    40621 gacccacata aagagcaaat cgctgttaaa gaagctaaaa aattgggaat cccagttgta
    40681 gcgatggttg acaccaatac tgatccagat gatatcgatg taatcatccc agctaacgat
    40741 gacgctatcc gtgctgttaa attgatcaca gctaaattgg ctgacgctat tatcgaagga
    40801 cgtcaaggtg aggatgcagt agcagttgaa gcagaatttg cagcttcaga aactcaagca
    40861 gattcaattg aagaaatcgt tgaagttgta gaaggtgaca acgcttaatt tatacaaata
    40921 gtaattacct aggagggcgg ggcttagccc ggctctccta ttttcaaaaa atataggaga
    40981 attaaaatgg cagaaattac agctaaactt gtaaaagagt tgcgtgaaaa atctggtgcc
    41041 ggtgttatgg acgctaaaaa agcgcttgta gaaacagacg gtgacatcga aaaagcgatt
    41101 gaattgcttc gtgaaaaagg tatggctaag gcagctaaga aagctgaccg tgttgctgca
    41161 gaaggtttga ctggtgttta tgttaacggt aatgttgcag cagttattga agtaaacgct
    41221 gaaactgact tcgttgcaaa aaacgctcaa ttcgttgaat tggtaaatac tacagctaaa
    41281 gtcattgctg aaggaaaacc tgctaataat gaagaagctc ttgctttgat aatgccttca
    41341 ggtgaaactc ttgaagctgc atacgtatct gcaacagcaa ctatcggaga gaaaatctca
    41401 ttccgtcgct ttgcattgat tgaaaaaaca gacgcacaac actttggagc ataccaacat
    41461 aacggtggac gtatcggtgt tatttcagtt gttgaaggtg gagacgaagc acttgctaaa
    41521 caattgtcaa tgcacatcgc agcgatgaaa ccaacagttc tttcttacaa agaattggat
    41581 gagcaattcg ttaaagatga gttggcacaa ttgaatcacg ttatcgacca agacaacgaa
    41641 agccgtgcaa tggttaataa accagctctt ccacacttga agtatggatc aaaagctcaa
    41701 ttaactgatg atgttattgc tcaagctgaa gctgacatca aagctgaatt ggctgcagaa
    41761 ggcaaaccag aaaaaatctg ggacaaaatt atcccaggta aaatggatcg cttcatgctt
    41821 gataatacta aagttgacca agcttacaca cttcttgcac aagtttacat catggatgac
    41881 agcaagacag ttgaagcata ccttgaatca gttaacgctt cggtagttga gtttgctcgc
    41941 tttgaagttg gtgaaggtat cgagaaagct gcaaacgact tcgaagctga agttgcagct
    42001 acaatggcag cagccttgaa taactaataa tagaaaggaa gcaatttgct tccttttttg
    42061 tatagggctt atatttttcc tgaaattgtt tttcccccag tctcactcga ttagaataat
    42121 taaaacaaaa agccctataa taagggctaa gtgcatttag gagactatac ttcaaattca
    42181 tagtaagcgc gtcataacaa ggtatctatc ctaattcccc aacttccagt atactagata
    42241 aaaaataatt atcggaggaa aggtattgta ctatgatgat tcaactaagt gatttaggtc
    42301 aagttcacat tgtttgtggc aagacagata tgaggcaggg aatagactca ttagcctatg
    42361 tagttaaaac ccactttgaa ttggattctt tctccggtca agtctttctc ttttgtggtg
    42421 gacgtaaaga ccgctttaaa gtcctttact gggatggtca aggattttgg ctactatata
    42481 aacgctttga gaacggaaaa ctgacttggc taagtacaga aaaggatgtc aaagctctcg
    42541 cacctgaaca agtagactag cttatgaagg gcttttctat cactccaaaa atatagtaga
    42601 ttgaaactag aatagtacac ctctgcttct aaaacattgt tagaaatcga tttgactgtc
    42661 ctgatcgatt tgtcctgttc ttatttcatt ttactataaa tccatcagaa agtcgtgatt
    42721 tctattgaaa tgaggacttt ctttttacac tcatctgctt tcaaaaagca ttctagtccg
    42781 tctccgatta acgatggact ttatcacctc cttctctagt ccttgtatga catcttccaa
    42841 agttcgaaag gctttattct taaatccacg tttacgaatc tctttccaca cttgttcaat
    42901 gggttcatct ctggtgtgta tggaggaata aaggtaaaac caatattagt cggaatcttt
    42961 aaggtacttg atttatgcca tatagcattg tccataacga gtaaaaaata atcatctgga
    43021 tgctcctatt cctaaagccc ctttagcgca tagctttggc tcagcttcta ttatcgctca
    43081 catcatccat cagaagttta atctgaaggt acccaattat cgccaagaag aagattgggc
    43141 taggatgggt ttaccaatca cacgtaagga aatctctaat cggcatatca agacgagtca
    43201 atactatttg gagccccttt ataacctctt gcgagagaga ctattgactc agcccttact
    43261 tcatgcggat gaaacttctt atagggtgct agagagtgat agtcagctga cttactattg
    43321 gacttttttg tctgggaaag ctgagaaaca agggattacg ctttaccatc atgtcctaat
    43381 cgatttgttc atatcttatt tcaatccatt ataaatagtg agaaatatct atcctatctt
    43441 ctagaatgtc ttccaaacgt ggaaactctc gtaaacaaag aggttttaga ggcctattta
    43501 ccatggacta aagttgtaca agaaaagtgc aaataagaaa tctccagatt aggaactatc
    43561 cgtgagttct ctagtctgga gatttttcaa tagacttcgt tattggacgg ttacaattca
    43621 taaagtgctg tagagagata acgttcaccg ttatctggtg ctagggcaag gactttttta
    43681 cctgtaccta attttttggc aacctcgatg gctccgtaga tagctgcagc tgaggaaatc
    43741 cctacaagga agccttcttt tccaccaatt tcacgtccga gtgcaagagc gtcatctgat
    43801 gttacacgaa cgataccatc ataggcttta gtatcaagtg tatcaggaat aaatccagct
    43861 gagatacctt gaattttgtg aggaccaggt ttttcaccag atagaatagc agattcatct
    43921 gcttctactg caaaaacttg aatgttagaa ttttctgatt tgagtgcatg agaaacacca
    43981 gaaatcgttc caccagtacc tactccagca acaaaggcat ctaatccatc tttaccgaaa
    44041 gcagctagta tctcagctcc tgttgttctt tcgtgtactt ctggattagc tggattgtca
    44101 aattgaagag gaaggaaacc atcacgttca gcagcgattt cttgagcctt agcaatagca
    44161 cctttcattc cctcgctacc aggagttagg acgagttcag caccataagc ttggataatt
    44221 ttacgtcgtt ctacactcat agtttcaggc ataacgatga cgactttata ccctttagca
    44281 gcacctaccc atgaaagtcc aataccggtg tttccacttg ttgcttcaac aatagtagaa
    44341 ccaagtttca gaataccatc ttgttcagct ttttcaatca tgctaagggc aatacggtct
    44401 tttacagatg aaccaggatt aaatgcttca agctttatat agacgtctgc agcaccttct
    44461 ggcacgatgt tgttaagttt aacaatcggt gtttgaccga ttaattcagt aatgttgtta
    44521 taaatagaca tatgaatacc tctttgtata agatatcttt agtataacgc tatccatacc
    44581 atttgtaaaa tatagaaatc ctatcgaagc gataggattt ctatatatca tagatcaaag
    44641 tcattaattt tcaagtgatt gcgttcagtt aattctagta aataggtgtg aaggaaaacg
    44701 atatcaggtt tcgtttgaat tgcttcattt tctagtatat tttggtacgc atctttttat
    44761 tttgctcgct aaagtagttg tgagaatgtc aacgaaacgc tgtattattc attgtttaca
    44821 ctaagtttac aggaacttca acctctcgta aaccttggtc agttaaagtg acttttccat
    44881 taaaaaactc cacaagtgca gctttaatag tttctttttc ttctttatca acataaatca
    44941 tcgtatcgac ttgatctgta aagtttgtat ccagctccat gagatcatgt tctttaagga
    45001 agttactgta ctcttggtac tgagcataag acatttgaat agcaatgcca gcctgttctt
    45061 ttatttcaat aataccaatt tctttgacag ctaaggcgac actgccggcg taagcacgaa
    45121 ttagtcctcc agcgcctagt ttaataccac caaagtagcg tgtcacgacc acacagacat
    45181 tggtgagatt gtgattttct agtaccccaa gcatgggaac accagcagta ccactaggct
    45241 caccatcatc acttgtacgt ttaatttcac tacgttctcc aataataaag gcagagcagt
    45301 tatgtgtcgc tttgtagtgt tcttttttga tggcagtaat gaagtcacga gcctcttctt
    45361 cgctataaac acgcttggca tggcagataa agcgagattt tttgatttct tcttggactt
    45421 ggccgtcctc tttaattgtc ctaaattcca tgatttaatt gtactaaaaa atcatctaaa
    45481 gtgctagttt ttacgaataa agaagtatga aagtaaattt agattatctc ggtcgtttat
    45541 ttactgagaa tgaattaaca gaagaagaac gtcagttggc ggagaaactt ccagcaatga
    45601 gaaaggagaa ggggaaactt ttctgtcaac gttgtaatag tactattcta gaagaatggt
    45661 atttgcccat cggtgcttac tattgtcgag agtgcttgct gatgaagcga gtcagaagtg
    45721 atcaaacttt atactatttt ccgcaggagg attttccgaa gcaagatgtt ctcaaatggc
    45781 gcggccaatt aactcctttt caagagaagg tgtcagaggg actgcttcaa gcagtagaca
    45841 agcaaaagcc aaccttagtt catgcggtaa caggagctgg aaagacagaa atgatttatc
    45901 aagtagtggc taaagtgatc aatgcgggtg gtgcagtgtg tttggctagt cctcgcatag
    45961 atgtttgttt ggagctgtac aagcgcctgc aacaggattt ttcttgcgga atagctttgc
    46021 tacatggaga atcggaacct tattttcgaa caccactagt tgttgcaaca acccatcagt
    46081 tattgaagtt ttatcaagct tttgatttgc tgatagtgga tgaagtagat gcttttcctt
    46141 atgttgataa tcccatgctt taccacgctg tcaagaatag tgtaaaggag aatggattga
    46201 gaatcttttt aacagcgact tcgaccaatg agttagataa aaaggtccgt ttaggagaac
    46261 taaaaagact gaatttaccg agacggtttc atggaaatcc gttgattatt ccaaaaccaa
    46321 tttggttatc ggattttaat cgctacttag acaagaatcg tttgtcacca aagttaaagt
    46381 cctatattga gaagcagaga aagacagctt atccgttact catttttgct tcagaaatta
    46441 agaaagggga gcagttagca gaaatcttac aggagcaatt tccaaatgag aaaattggct
    46501 ttgtatcttc tgtaacagag gatcgattag agcaagtaca agcttttcga gatggagaac
    46561 tgacaatact tatcagtacg acaatcttgg agcgtggagt taccttccct tgtgtggatg
    46621 ttttcgtagt agaggccaat catcgtttgt ttaccaagtc tagtttgatt cagattggtg
    46681 gacgagttgg acgaagcatg gatagaccga caggagattt gcttttcttc catgatgggt
    46741 taaatgcttc aatcaagaag gcgattaagg aaattcagat gatgaataag gaggctggtc
    46801 tatgaagtgc ttgttatgtg ggcagactat gaagactgtt ttaactttta gtagtctctt
    46861 acttctgagg aatgatgact cttgtctttg ttcagactgt gattctactt ttgaaagaat
    46921 tggggaagag aactgtccaa attgtatgaa aacagagttg tcaacaaagt gtcaagattg
    46981 tcaactttgg tgtaaagaag gagttggagt cagtcataga gcgattttta cttacaatca
    47041 agctatgaag gattttttca gtcggtataa gtttgatgga gacttcctgt taagaaaagt
    47101 tttcgcttca tttttaagtg aggagttgaa aaagtacaaa gagtatcaat ttgttgtaat
    47161 tcccctaagt cctgatagat atgctaatag aggatttaat caggttgagg gcttggtaga
    47221 ggcagcaggc tttgagtatc tagatttatt agagaaaaga gaagagagag ccagttcttc
    47281 taaaaatcgt tcagagcgct tggggacaga acttcctttc tttattaaaa gtggagtcac
    47341 tattcctaaa aaaatcctac ttatagatga tatctatact acaggagcaa ctataaatcg
    47401 tgttaagaaa ctgttggaag aagccggtgc taaggatgta aaaacatttt cccttgtaag
    47461 atgaggaaaa aatttgcaaa aatagaatga aagcgttata ataaaatcat aaaaacaaaa
    47521 atgtttagaa agaaggtact catatgatta aatatagtat ccgtggtgaa aacctagaag
    47581 taacagaagc aattcgtgat tatgtagttt ctaaactcga aaagatcgaa aagtacttcc
    47641 aaccagaaca agagttggat gcccgaatta acttaaaagt ttatcgtgaa aaaacggcta
    47701 aagtggaagt aacgattccg cttggatcta ttactctccg cgcagaagat gtatctcaag
    47761 atatgtatgg ttcaattgac cttgtaactg ataaaattga acgtcagatt cgtaaaaata
    47821 aaacaaaaat cgagcgtaaa aataaaaata aggtagcaac tggtcaatta tttacagatg
    47881 ctttggtgga agattcaaat attgtccagt ctaaagttgt tcgttcaaaa caaattgatt
    47941 taaaaccaat ggatttggaa gaagcaattc tacaaatgga tttattgggg catgatttct
    48001 ttatctatgt ggatgttgaa gatcagacaa ccaatgtgat ttatcgtcgt gaggatggcg
    48061 aaattggttt gttagaggtt aaagaatctt aatttcaata tgtgtaaagg taggtttact
    48121 gaattgtaaa ctaccttttt cttataattg atagaattac tgattacact tttaaaaagt
    48181 cgctttttga ggggtattat ggtataatgg gtgccaagag gttttgaatg aaaaaatttt
    48241 atgtaagtcc aatttttcct attctagtag gattgattgc gtttggagtc ttatccactt
    48301 tcattatttt tgttaataat aatctgttga cggttttaat tttgtttctt tttgtaggag
    48361 gctatgtttt tttatttaag aaactgagag tgcattatac aaggagtgat gtagaacaga
    48421 tacagtatgt aaaccaccaa gcggaagaaa gtttgacagc tctattggaa cagatgcctg
    48481 taggtgttat gaaattgaat ttatcttctg gagaggttga gtggtttaat ccctatgctg
    48541 aattgatttt gaccaaggaa gatggtgatt ttgatttaga agctgttcaa acgattatca
    48601 aggcttcagt aggaaatccg tctacttatg ccaagcttgg tgagaagcgt tatgctgttc
    48661 atatggatgc ttcttccggt gttttgtatt ttgtagatgt atccagggaa caagccataa
    48721 cagatgaatt ggtaacaagt cgaccagtga ttgggattgt ctctgtggat aattatgatg
    48781 atttggagga tgcaacttct gagtcagata ttagtcaaat caatagtttt gtagctaatt
    48841 ttatatcaga gttttcagaa aaatacatga tgttttctcg tcgggtaagt atggatcgat
    48901 tttatctatt tactgactac acggtgcttg agggcttgat gaatgataaa ttttctgtta
    48961 ttgatgcttt cagagaagag tcgaaacaga gacagttgcc cttgacttta agtatgggat
    49021 tttcttatgg cgatggaaat catgatgaga tagggaaagt tgctttgctc aatttgaact
    49081 tggctgaagt acgtggtggc gaccaggtgg ttgttaagga aaacgacgaa acgaaaaatc
    49141 cagtttattt tggtggtggg tctgctgctt caatcaagcg tacacggact cgtacgcgcg
    49201 ctatgatgac agctatttca gataagattc ggagtgtaga tcaggttttt gtagtcggtc
    49261 acaaaaattt agacatggat gctttgggct ctgctgtagg tatgcagttg ttcgccagca
    49321 atgtgattga aaatagctat gctctttatg atgaagaaca aatgtctcca gatattgaac
    49381 gagctgtttc attcatagaa aaagaaggag ttacgaagtt gttgtctgtt aaggatgcaa
    49441 tggggatggt gaccaatcgt tctttgttga ttcttgtaga ccattcaaag acagccttaa
    49501 cattatcaaa agaattttat gatttattta cccaaaccat tgttattgac caccatagaa
    49561 gggatcagga ttttccagat aatgcagtca ttacttatat cgaaagtggt gcaagtagtg
    49621 ccagtgagtt ggtaacggaa ttgattcagt tccagaattc taagaaaaat cgtttgagtc
    49681 gtatgcaagc aagtgttttg atggctggta tgatgttgga tactaaaaat ttcacctcgc
    49741 gagtaactag tcggacattt gatgttgcta gctatctcag aacgcgcgga agtgatagta
    49801 ttgctatcca ggaaattgct gcgacagatt ttgaagaata tcgtgaggtt aatgaactta
    49861 ttttacaggg gtgtaaatta ggttcagatg tactaatagc agaggctaag gacacgaaat
    49921 gctatgatac agttgttatt agtaaggcag cagatgccat gttagccatg tcaggtattg
    49981 aagcgagttt tgttcttgcg aagaatacac aaggatttat ctctatctca gctcgaagtc
    50041 gtagtaaact gaatgtacaa cggattatgg aagagttagg cggtggaggc cactttaatt
    50101 tggcagcagc tcaaattaaa gatgtaacct tgtcagaagc aggtgaaaaa ctgacagaaa
    50161 ttgtattaaa tgaaataaag gaaaaggaga aagaagaatg aaagtaatct ttttagcaga
    50221 tgttaaagga aaaggtaaaa aaggcgaaat taaggaagta ccaacagggt atgcgcaaaa
    50281 ctttcttatc aaaaagaatc tagccaaaga agcgactgct caagctgtag gtgaacttcg
    50341 tggtaaacaa aaatcggaag aaaaagctca cgctgagatg attgcagaag gaaaagcaat
    50401 taaagcacaa cttgaagcag aagaaactgt tgtagaattt gttgaaaaag ttggtccaga
    50461 tggtcgtacc tttggttcta ttaccaataa gaagattgca gaagaattgc aaaagcaatt
    50521 tggaattaag attgataaac gtcatattca agtacaagct ccgattcgag cggttggttt
    50581 gattgatgtg ccagtgaaaa tctatcaaga tatcacaagt gtaatcaatc ttcgtgtgaa
    50641 agaaggataa gtttacacct tcttgacaag attgtaaaag gaagggaagt ctgatggcag
    50701 aagtagaaga gttacgagta caacctcaag atatcttagc tgagcaatcc gttttagggg
    50761 ctatctttat tgatgagagt aaacttgttt ttgtgcgaga atacattgag tctcgggact
    50821 tttttaagta tgcccatcgt ttgattttcc aagccatggt cgatttatcc gatcgtggtg
    50881 atgccataga tgcaacaacg gttcgtacta tccttgataa tcaaggtgat ttacagaata
    50941 ttggtggctt gtcttacttg gttgagattg ttaattctgt gccaacttct gctaatgcgg
    51001 agtattatgc taagattgtt gcagaaaaag caatgctacg tcgtttaatt gccaagttga
    51061 cagagtctgt caaccaagct tacgaagcgt cacaaccagc tgatgaaatt attgctcagg
    51121 cagaaaaagg gttgattgat gtcagtgaaa atgcaaatcg aagcgggttt aagaacattc
    51181 gagatgtgtt gaatctcaac tttggaaatc tggaagctcg ctcgcaacaa acgaccgata
    51241 ttacaggtat tgcgacaggt tatcgtgatt tggatcatat gacaacagga cttcatgagg
    51301 aggagttgat tatcttagca gctcgtccag cagttggtaa gacagcattt gccttgaata
    51361 tcgctcagaa tattgggact aagttggaca aaacggttgc tattttttca ctcgaaatgg
    51421 gtgcggaaag cttggtagac cgtatgttag ctgcagaagg cttggtggag tcacattcta
    51481 tccgtacagg gcaattgaca gatgaggagt ggcaaaaata tactattgct cagggtaatc
    51541 tagctaacgc cagtatctat atcgatgata cgccaggtat tcggattaca gagattcgtt
    51601 ctcgttctcg taaattggct caagaaactg gaaatcttgg tttgattttg atagactatt
    51661 tgcaacttat cacgggaact ggtcgagaaa atcgtcaaca agaagtttct gaaatttctc
    51721 gtcagttgaa aatactagcc aaggaattga aggttccagt aatcgctctg agtcagcttt
    51781 ctcgtggtgt agaacaacgt caggacaaga gaccggtctt gtctgatatt cgtgaatctg
    51841 ggtctattga gcaggacgct gatatcgtag cttttctcta tcgcgatgac tactatgaac
    51901 gtggtggtga agaagaggag ggtatcccaa ataataaggt ggaagttatt atcgagaaaa
    51961 accgtagtgg agctcgtgga acagtggaat tgattttcca aaaagaatac aataaatttt
    52021 caagtatctc aaagagggag gcataagatg tcagatgcat ttacagatgt agccaagatg
    52081 aaaaaaatca aagaagaaat caaggcacat gagggacaag tcgtagaaat gactttggag
    52141 aatggtcgta agcgccaaaa aaatagattg ggtaagctaa ttgaagttta tccatcccta
    52201 tttattgtgg agtttgggga tgtggaagga gataaacaag ttaatgttta cgttgaatcc
    52261 tttacttact cagatattct tacagaaaag aatttgattc attatcttga ctaaagtgag
    52321 aaattttctc actttttctt ttttctccga ataatttagg tgaaggcaat catcgcttta
    52381 tattattttt taaggaggaa gaatgaaaat tttaccgttt atagcaagag gaacaagtta
    52441 ttacttgaag atgtcagtta aaaagcttgt tcctttttta gtagtaggat tgatgctagc
    52501 agctggtgat agtgtctatg cctattccag aggaaatgga tcgattgcgc gtggggatga
    52561 ttatcctgct tattataaaa atgggagcca ggagattgat cagtggcgca tgtattctcg
    52621 tcagtgtact tcttttgtag cctttcgttt gagtaatgtc aatggttttg aaattccggc
    52681 agcttatgga aatgcgaatg aatggggaca tcgtgctcgt cgggaaggtt atcgtgtaga
    52741 taatacaccg acgattggtt ccattacttg gtctactgca ggaacttatg gtcatgttgc
    52801 ctgggtgtca aatgtaatgg gagatcagat tgagattgag gaatataact atggttatac
    52861 agaatcctat aataaacgag ttataaaagc aaacacgatg acaggattta ttcattttaa
    52921 agatttggat agtggcagtg ttgggaatag tcaatcctca gcttcaacag gcggaactca
    52981 ttattttaag accaagtctg ctattaaaac tgaaccccta gttagtgcaa ctgtgattga
    53041 ttactattat cctggggaga aggttcatta tgatcagata cttgaaaaag acggctataa
    53101 gtggttgagt tatactgcct ataatggaag ctatcgttat gttcaattgg aggctgtgaa
    53161 taaaaatcct ctaggtaatt ctgttctttc ttcaacagga ggaactcatt attttaagat
    53221 caagtctgct attaaaactg aacccctagt tagtgcaact gtgattgatt actattatcc
    53281 tggagagaag gttcattatg atcagatact tgaaaaagac ggctataagt ggttgagtta
    53341 tacggcttat aacggaagtc gtcgctatat acagctagag ggagtgactt cttcacaaaa
    53401 ttatcagaat caatcaggaa atatctctag ctatggatcc aataatagtt caactgtcgg
    53461 ttggaagaaa ataaatggta gttggtatca tttcaaatca aatggttcta aatcaacagg
    53521 atggctgaaa gacggttcta gctggtatta tttgaaatta tctggtgaaa tgcagacagg
    53581 atggttaaag gagaatggct cgtggtatta tctgggtagt tcaggggcaa tgaaaacagg
    53641 ctggtaccag gtctctggta agtggtatta ttcttactct tcaggcgcct tagctattaa
    53701 tacgacggtg gatggctaca gagtaaacag tgatggagaa cgagtataga aaattggagt
    53761 aggagaaatt tcctgctctt ttctgtaagc agtttccttg acatttttct tattttgcgc
    53821 tatcatatat acatataata tatgggagtc tgtgtacagt ctgagaggaa gtgttaaact
    53881 tcgaccgcac ctgatctggg taatgccagc ggagggaacg atacttagtc taattttgca
    53941 ccttttccat gtatggtaaa ggtttttctt ttttttaaaa ggaaaacgag aagaggaggt
    54001 tcttatgaaa gcaagcattg ccttgcaagt tttaccccta gcacagggga ttgatcggat
    54061 agctgttatt gatcaggtca ttgcttatct gcaaactcaa gaagtgacga tggtagtgac
    54121 accatttgaa acggtcttgg aaggggagtt tgatgagctt atgcgcattc taaaagaagc
    54181 gctggaagtg gcagtgcagg aggcagacaa tgtctttgcc aatgtcaaaa taaatgtagg
    54241 agagatttta agtattgatg agaaacttga aaagtatact gagacgacac attagtctat
    54301 tgggctttct cggagtattg tcaatctggc agttagcagg ttttcttaaa cttctcccca
    54361 agtttatcct gccgacacct cttgaaattc tccagccctt tgttcgtgac agagaatttc
    54421 tctggcacca tagctgggcg accttgagag tggctttact ggggctgatt ttgggagttt
    54481 tgattgcctg tcttatggct gtgctcatgg atagtttgac ttggctcaat gacctgattt
    54541 accctatgat ggtggtcatt cagaccattc cgaccattgc catagctcct atcctggtct
    54601 tgtggctggg ttatgggatt ttgcccaaga ttgtcttgat tatcttaaca acaacctttc
    54661 ccatcatcgt tagtattttg gacggtttta ggcattgtga caaggatatg ctgactttgt
    54721 ttagtctgat gcgagcaaac ccttggcaaa tcctgtggca ttttaaaatc ccggttagcc
    54781 tgccttactt ttatgcaggt ctgagggtca gtgtctccta cgcctttatc acaactgtgg
    54841 tatctgagtg gttgggaggt tttgaaggtc ttggtgttta tatgattcag tctaaaaaac
    54901 tgtttcagta tgataccatg tttgccatta ttattctggt gtcgattatc agtcttttgg
    54961 gtatgaagct ggtcgatatc agtgaaaaat atgtgattaa atggaaacgt acttaaaata
    55021 gagcgttttt gaaaaagaaa agaggaaatc aaaatgaaga aaacatggaa agtgttttta
    55081 acgcttgtaa cagctcttgt agctgttgtg cttgtggcct gtggtcaagg aactgcttct
    55141 aaagacaaca aagaggcaga acttaagaag gttgacttta tcctagactg gacaccaaat
    55201 accaaccaca cagggcttta tgttgccaag gaaaaaggtt atttcaaaga agctggagtg
    55261 gatgttgatt tgaaattgcc accagaagaa agttcttctg acttggttat caacggaaag
    55321 gcaccatttg cagtgtattt ccaagactac atggctaaga aattggaaaa aggagcagga
    55381 atcactgccg ttgcagctat tgttgaacac aatacatcag gaatcatctc tcgtaaatct
    55441 gataatgtaa gcagtccaaa agacttggtt ggtaagaaat atgggacatg gaatgaccca
    55501 actgaacttg ctatgttgaa aaccttggta gaatctcaag gtggagactt tgagaaggtt
    55561 gaaaaagtac caaataacga ctcaaactca atcacaccga ttgccaatgg cgtctttgat
    55621 actgcttgga tttactacgg ttgggatggt atccttgcta aatctcaagg tgtagatgct
    55681 aacttcatgt acttgaaaga ctatgtcaag gagtttgact actattcacc agttatcatc
    55741 gcaaacaacg actatctgaa agataacaaa gaagaagctc gcaaagtcat ccaagccatc
    55801 aaaaaaggct accaatatgc catggaacat ccagaagaag ctgcagatat tctcatcaag
    55861 aatgcacctg aactcaagga aaaacgtgac tttgtcatcg aatctcaaaa atacttgtca
    55921 aaagaatacg caagcgacaa ggaaaaatgg ggtcaatttg acgcagctcg ctggaatgct
    55981 ttctataaat gggataaaga aaatggtatc cttaaagaag acttgacaga caaaggcttc
    56041 accaacgaat ttgtgaaata atgacagaaa ttagactaga gcacgtcagt tatgcctatg
    56101 gtcaggagag gattttagag gatatcaacc tacaggtgac ttcaggcgaa gtggtttcca
    56161 tcctaggccc aagtggtgtt ggaaagacca ccctctttaa tctaatcgct gggattttag
    56221 aagttcagtc agggagaatt gtccttgatg gtgaagaaaa tcccaagggg cgcgtgagtt
    56281 atatgttgca aaaggatctg ctcttggagc acaagacggt gcttggaaat atcattctgc
    56341 ccctcttgat tcaaaaggtg gataaggcag aagctatttc ccgagcggat aaaattcttg
    56401 cgaccttcca gctgacagct gtaagagaca agtatcctca tgaacttagc ggtgggatgc
    56461 gccagcgtgt agccttactc cggacctacc tttttgggca caagctcttt ctcttagatg
    56521 aggcctttag cgctttggat gagatgacaa agatggaact ccacgcttgg tatcttgaga
    56581 ttcacaagca gttgcagcta acaaccctga tcatcacgca tagtattgag gaggccctca
    56641 atctcagcga ccgcatctat atcttgaaaa atcgccctgg gcagattgtt tcagaaatta
    56701 aactagattg gtctgaagat gaggacaagg aagtccaaaa gattgcctat aaacgtcaaa
    56761 tcttggcaga attaggctta gataagtaga aaaataggga gttggtgaag attatccttt
    56821 accagcgccc tttttctttt aaaaatgaga aaatttcggt ataatagtca aacaaggtca
    56881 aggtttaaag agagaggtgg gtttgttatg agatttaaaa atacatcgga tcatattgag
    56941 gcctacatca aggcgatttt agatcaatct ggtatcgtgg agttgcaacg gagtcagttg
    57001 gcagatacct ttcaggttgt tcctagtcag attaactacg tgatcaagac acgctttacg
    57061 gaaagtagag gctacttggt tgaaagtaag cgtggtggtg gaggctacat tcgtatagga
    57121 cgaattgagt tttctagtca tcatgaaatg ctccgggagc tgctttactc gattggtgag
    57181 cgagtcagtc aagaaattta tgaggatatt ctccagcttt tggttgagca ggaattgatg
    57241 accaagcagg agatgaattt gctagaatca gtagctttgg atcgcgtttt aggagaagaa
    57301 gctccagttg ttcgagcaaa catgctacgt cagatcatac aagaggtaga tagaaaaggg
    57361 aagtaagatg aactattcaa aagcattgaa tgaatgtatc gaaagtgcct acatggttgc
    57421 tggacatttt ggagctcgtt atctagagtc ttggcacttg ttgattgcca tgtctaatca
    57481 cagttatagt gtagcagggg caactttaaa tgattatccg tatgagctgg accgtttaga
    57541 agaggtggct ttggaactga ctgaaacgga ctatagccag gatgaaactt ttacggaatt
    57601 gccgttctcc cgtcgtttgc agattctttt tgacgaagca gagtatgtag cgtcagtggt
    57661 ccatgctaag gtgctaggga cagagcacgt cctctatgcg attttgcatg atggcaatgc
    57721 cttggcgact cgtatcttgg agagggctgg tttttcttat gaagacaaga aagatcaggt
    57781 caagattgct gctcttcgtc gaaatttaga agaacgggca ggctggactc gtgaagatct
    57841 caaggcttta cgccaacgcc atcgtacagt agctgacaag caaaattcta tggccaatat
    57901 gatgggcatg ccgcagactc ctagtggtgg tctcgaggac tatacgcatg atttgacaga
    57961 gcaagcgtgt tctggcaagt tagaaccagt catcggtcgg gacaaggaaa tctcacgtat
    58021 gattcaaatc ttgagccgga agactaagaa caaccctgtc ttggttgggg atgctggtgt
    58081 cgggaaaaca gctctggcgc ttggtcttgc tcagcgtatt gctagtggtg acgtgcctgc
    58141 ggaaatggct aagatgcgcg tgttagaact tgatttgatg aatgtcgttg cagggacacg
    58201 cttccgtggt gactttgaag aacgcatgaa taatatcatc aaggatattg aagaagatgg
    58261 ccaagtcatc ctctttatcg atgaactcca caccatcatg ggttctggta gcgggattga
    58321 ttcgactctg gatgcggcca atatcttgaa accagccttg gcgcgtggaa ctttgagaac
    58381 ggttggtgcc accactcagg aagaatatca aaaacatatc gaaaaagatg cggctctttc
    58441 tcgtcgtttc gctaaagtga cgattgaaga accaagtgtg gcagatagta tgactatttt
    58501 acaaggtttg aaggcgactt atgagaaaca tcaccgtgta caaatcacag atgaagcggt
    58561 tgaaacagcg gttaagatgg ctcatcgtta tttaaccagt cgtcacttgc cagactctgc
    58621 tatcgacctc ttggacgaag cagcagcaac agtgcaaaat aaggtaaagt atgtaaaagc
    58681 agacgattca gatttgagtc cagctgataa ggccctgatg gatggcaagt ggaaacaggc
    58741 agcccagcta atcgcaaaag aagaggaagt acctgtctac aaagacttgg tgacagagtc
    58801 tgatattttg accaccttga gtcgcttgtc aggaatccca gttcaaaaac tgactcaaac
    58861 ggatgctaag aagtatctaa atcttgaagc agaactccat aaacgtgtca tcggtcaaga
    58921 tcaagctgtt tcaagcatta gtcgtgcgat tcgccgtaat cagtcaggaa ttcgcagtca
    58981 caagcgtccg atcggttcct ttatgttcct aggacccaca ggtgtcggta agaccgagtt
    59041 ggccaaggct ttggcagaag ttctctttga tgacgaatca gcccttatcc gctttgatat
    59101 gagtgagtat atggagaaat tcgcagccag ccgtctaaat ggagctcctc caggctatgt
    59161 gggttacgaa gaaggtggag agttgacaga gaaggttcgc aataaaccct attccgttct
    59221 cctctttgat gaggtagaga aggcccaccc agatatcttt aatgttctct tgcaagttct
    59281 ggatgacggt gttttgacag atagcaaggg acgcaaggtc gatttttcaa ataccattat
    59341 cattatgaca tcgaacctag gtgcgactgc ccttcgtgat gataagactg ttggttttgg
    59401 ggctaaggat attcgttttg accaggaaaa tatggaaaaa cgcatgtttg aagaactgaa
    59461 aaaagcttat agaccggaat tcatcaaccg tattgatgag aaggtggtct tccatagcct
    59521 atctagtgac catatgcagg aagtggtgaa gattatggtc aagcctttag tggcaagttt
    59581 ggctgaaaaa ggcattgact tgaaattaca agcttcagct ctgaaattgt tagcaaatca
    59641 aggatatgac ccagagatgg gagctcgccc acttcgcaga accctgcaaa cagaagtgga
    59701 ggacaagttg gcagaacttc ttcttaaggg agatttagtg gcaggcagca cacttaagat
    59761 tggtgtcaaa gcaggccagt taaaatttga tattgcataa aagaataaaa gtatcagcat
    59821 ctgaccataa gtcacagtgg agtgaaactc aatgaaaatc aaagagcaaa ctaggcagct
    59881 agccgcaggt tgctcaaaac actggtttga ggttgcagat agagctgacg tggtttgaag
    59941 agattttcga agagtatgaa actaaaacct atagcttcta aacgatccgt ggttttcacc
    60001 attcaacaca aaattcatat gtttattacc ctccgtcgta tttgtcttag agcgtgtgta
    60061 gtagaaaaag agcagtctta tctgaaattt ttattctttc aaaagagacc tgtttctttt
    60121 ttgcatgtca aatccgttct agctggtatt tgaaaaatca aactaatatt caatgaaaat
    60181 caaagaacaa actaggcagc tagccacagg ttgctcaaaa cactgttttt agattgtaga
    60241 tagagctgac gtggtttgaa gagattttcg aagagtataa gctgcaagat gaatgatttt
    60301 cttgtattga cgttgttgtt gacaaaaagt agcggataaa tgaaatccat tccattatca
    60361 tagatgatag gctggtagga aattttcaaa tagcatacag gaaatagatg tatggagttc
    60421 tggtagtaga aagggagaga gatgaacatt ttagttgcag atgacgagga aatgattaga
    60481 gaaggaattg cagcatttct gacagaagag ggttatcatg tcattatggc taaggatgga
    60541 caagaggtct tggaaaaatt tcaagatctc cctatccatc tcatggtact ggatttaatg
    60601 atgcctagga agagtggttt tgaagtgtta aaagaaatca atcaaaagca cgatattcct
    60661 gtcatcgtct tgagtgctct gggagatgaa actactcagt cacaggtatt tgatctctat
    60721 gctgatgatc atgtgacaaa acctttttct ttggtactgc ttgtcaagcg tattaaggcg
    60781 cttatcagac gttactacgt catagaggat atttggcgat atcaggatgt aacagtggat
    60841 tttacctctt acaaagcaca ttataaaaat gaagaaattg atctcaaacc aaaggaatta
    60901 ctggtactaa agtgtttgat tcagcataaa aatcaagttt taagtagaga gcagatattg
    60961 gaagaaattt caaaagatgt agctgattta ccttgtgata gggtcgttga tgtctatatt
    61021 cgtactcttc gcaaaaaatt agctttagat tgtatcgtga ctgtgaaaaa tgttgggtat
    61081 aagattagct tatgataaaa aatcctaaat tattaaccaa gtctttttta agaagttttg
    61141 caattctagg tggtgttggt ctagtcattc atatagctat ttatttgacc tttccttttt
    61201 attatattca actggagggg gaaaagttta atgagagcgc aagagtgttt acggagtatt
    61261 taaagactaa gacatctgat gaaattccaa gcttactcca gtcttattca aagtccttga
    61321 ccatatctgc tcaccttaaa agagatattg tagataagcg gctccctctt gtgcatgact
    61381 tggatattaa agatggaaag ctatcaaatt atatcgtgat gttagatatg tctgttagta
    61441 cagcagatgg taaacaggta acagtgcaat ttgttcacgg ggtggatatc tacaaagaag
    61501 caaagaatat tttgcttttg tatctcccat atacattttt ggttacaatt gctttttcct
    61561 ttgttttttc ttatttttat actaaacgct tgctcaatcc tcttttttac atttcagaag
    61621 tgactagtaa aatgcaagat ttggatgaca atattcgttt tgatgaaagt aggaaagatg
    61681 aagttggtga agttggaaaa cagattaatg gtatgtatga gcacttgttg aaggttattc
    61741 atgagttgga aagtcgtaat gagcaaattg taaaattgca aaatcaaaag gtttcctttg
    61801 tccgtggagc atcacatgag ttgaaaaccc ctttagccag tcttagaatt atcctagaga
    61861 atatgcagca taatattgga gattacaaag atcatccaaa atatattgca aagagtataa
    61921 ataagattga ccagatgagc cacttattag aagaagtact ggagtcttct aaattccaag
    61981 agtggacaga gtgtcgtgag accttgactg ttaagccagt tttagtagat attttatcac
    62041 gttatcaaga attagctcat tcaataggtg ttacaattga aaatcaattg acagatgcta
    62101 ccagggtcgt catgagtctt agggcattgg ataaggtttt gacaaacttg attagtaatg
    62161 caattaaata ttcagataaa aatgggcgcg taatcatatc cgagcaagat ggctatctct
    62221 ctatcaaaaa tacatgtgcg cctctaagtg accaagaact agaacattta tttgatatat
    62281 tctatcattc tcaaatcgtg acagataagg atgaaagttc cggtttgggt ctttacattg
    62341 tgaataatat tttagaaagc tatcaaatgg actatagttt tctcccttat gaacacggta
    62401 tggaatttaa gattagcttg tagacagatt agttttttat taaagttcat atagggttaa
    62461 cataagtgtg ttattctttg catagataaa agaaaggata ctaatatggt attagcgatt
    62521 attttagtaa cattctttat tcgattgatt tttttaaagc gttcgataga gaatgagaaa
    62581 cgaatcctta gcaatggcgg gaaagaattt ggagttgaga atacaaaacg attaactatg
    62641 gctcatattg ttttttatct ctcttgcttg gttgaggcag tggtgcacaa gacaattttt
    62701 gatggcatgg gtatggttgg tttggtcttg cttatttttt ctatgctgat gttgatgttg
    62761 gtgattcact tgttgggaga tatttggaca gtgaagctta tgcttgtcaa taatcacaaa
    62821 tatgtagatc atatcttgtt taggacagta aaacatccta attacttttt aaatattctt
    62881 cctgagttga ttggcttgac cttgttgagt catgcttatg tgacttttgt tttagttttt
    62941 ccagtttatg cagttatttt gtatcgacga atagctgaag aggaaaagct attacatgaa
    63001 gttataatcc caaatggaag cataaagaga taaatacaaa attcgattta tatacagttc
    63061 atattgaagt gatatagtaa ggttaaagaa aaaatataga aggaaataaa catgtttgca
    63121 tcaaaaagcg aaagaaaagt acattattca attcgtaaat ttagtattgg agtagctagt
    63181 gtagtagttg ccagtcttgt tatggggagt gtggttcatg cgacagagaa cgagggaagt
    63241 acccaagcag ccactttttc taatatggca aataaaagtc agacagaaca aggagaaatc
    63301 aatatagaac gagataaggc aaagacagcg gtcagtgaat ataaagaaaa aaaagtgagt
    63361 gagatctata caaaattaga gagagataga cataaagata ctgtagatct agttaacaag
    63421 ttgcaagaga ttaagaacga gtatttgaat aaaatagttc aatcaacctc aaaaaccgaa
    63481 atacagggac ttattacaac aagtcgatca aaactagatg aagctgtgtc taaatataaa
    63541 aaggccccat cttcttcgtc aagttcaggc tcttccacta aaccggaagc ttcagataca
    63601 gcgaagccaa acaagccgac agaactagaa aaaaaggtag cagaagctga gaagaaggtt
    63661 gaagaagcta agaagaaagc caaggatcaa aaagaagaag attaccgtaa ctacccaacc
    63721 attacttaca aaacgcttga acttgaaatt gctgagtccg atgtggaagt taaaaaagcg
    63781 gagcttgaac tagtaaaaga ggaagctaag gaacctcgaa acgaggaaaa agttaagcaa
    63841 gcaaaagcga aagttgagag tgaagaaact gaggctacaa ggttagaaaa aatcaagaca
    63901 gatcgtaaaa aagcagaaga agaagctaaa cgaaaagcag cagaagaaga taaagttaaa
    63961 gaaaaaccag ctgaacaacc aaaaccagcg ccggctcctc aaccagaaaa accagctcca
    64021 aaaccagaga atccagctcc aaaaccagag aatccagctc caaaaccaga aaaaccagct
    64081 gaacaacaag ctgaagaaga ctatgctcgt agatcagaag aagaatataa tcgcttgact
    64141 caacagcaac cgccaaaaac tgaaaaacca gcacaaccat ctactccaaa aacaggctgg
    64201 aaacaagaaa acggtatgtg gtacttctac aatactgatg gttcaatggc gacaggatgg
    64261 ctccaaaaca atggctcatg gtactacctc aacagcaatg gcgctatggc gacaggatgg
    64321 ctccaaaaca atggttcatg gtactatcta aacgctaatg gttcaatggc aacaggatgg
    64381 ctccaaaaca atggttcatg gtactaccta aacgctaatg gttcaatggc gacaggatgg
    64441 ctccaataca atgg
//
LOCUS       DAVBNZ010000005        60299 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000005 DAVBNZ010000000
VERSION     DAVBNZ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60299
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.005"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..734
                     /locus_tag="VQ860_000279"
     CDS             <1..734
                     /locus_tag="VQ860_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3118777.1"
                     /translation="QLNQDCLIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQ
                     SDWKVQYTRCLDIIFPELDKIVGKHSEYTYQLLTRYPNPQKRLEARFDKLIEIKRLTA
                     SKIQDILSVAPRSIGTTSPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVT
                     GIGGRLGAVILAEIRNIHAFDNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRW
                     ALIQAAKACARFSPAFKAYLKTKLE"
     gene            complement(1035..2924)
                     /locus_tag="VQ860_000280"
     CDS             complement(1035..2924)
                     /locus_tag="VQ860_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET3118778.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAKLADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKDQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            3062..4627
                     /locus_tag="VQ860_000281"
     CDS             3062..4627
                     /locus_tag="VQ860_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3118779.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEITFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYN
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            4627..5367
                     /locus_tag="VQ860_000282"
     CDS             4627..5367
                     /locus_tag="VQ860_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3118780.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(5476..5691)
                     /locus_tag="VQ860_000283"
     CDS             complement(5476..5691)
                     /locus_tag="VQ860_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118781.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(6562..7812)
                     /gene="ilvA"
                     /locus_tag="VQ860_000284"
     CDS             complement(6562..7812)
                     /gene="ilvA"
                     /locus_tag="VQ860_000284"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET3118782.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7862..8218)
                     /locus_tag="VQ860_000285"
     CDS             complement(7862..8218)
                     /locus_tag="VQ860_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3118783.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(8456..8692)
                     /locus_tag="VQ860_000286"
     CDS             complement(8456..8692)
                     /locus_tag="VQ860_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118784.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERADATKSARYIAKWILRNKKH"
     gene            complement(8799..9821)
                     /gene="ilvC"
                     /locus_tag="VQ860_000287"
     CDS             complement(8799..9821)
                     /gene="ilvC"
                     /locus_tag="VQ860_000287"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3118785.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9887..10363)
                     /gene="ilvN"
                     /locus_tag="VQ860_000288"
     CDS             complement(9887..10363)
                     /gene="ilvN"
                     /locus_tag="VQ860_000288"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET3118786.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(10356..12056)
                     /locus_tag="VQ860_000289"
     CDS             complement(10356..12056)
                     /locus_tag="VQ860_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET3118787.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVKFHA
                     "
     gene            complement(12257..13924)
                     /locus_tag="VQ860_000290"
     CDS             complement(12257..13924)
                     /locus_tag="VQ860_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET3118788.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13927..14292)
                     /locus_tag="VQ860_000291"
     CDS             complement(13927..14292)
                     /locus_tag="VQ860_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3118789.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(14449..14637)
                     /locus_tag="VQ860_000292"
     CDS             complement(14449..14637)
                     /locus_tag="VQ860_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET3118790.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(14753..15238)
                     /locus_tag="VQ860_000293"
     CDS             complement(14753..15238)
                     /locus_tag="VQ860_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET3118791.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(15507..17051)
                     /locus_tag="VQ860_000294"
     CDS             complement(15507..17051)
                     /locus_tag="VQ860_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET3118792.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIRDAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMESEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            17264..17566
                     /gene="gatC"
                     /locus_tag="VQ860_000295"
     CDS             17264..17566
                     /gene="gatC"
                     /locus_tag="VQ860_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET3118793.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            17566..19032
                     /gene="gatA"
                     /locus_tag="VQ860_000296"
     CDS             17566..19032
                     /gene="gatA"
                     /locus_tag="VQ860_000296"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET3118794.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            19032..20474
                     /gene="gatB"
                     /locus_tag="VQ860_000297"
     CDS             19032..20474
                     /gene="gatB"
                     /locus_tag="VQ860_000297"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET3118795.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEIQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDANQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            20598..21641
                     /locus_tag="VQ860_000298"
     CDS             20598..21641
                     /locus_tag="VQ860_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HET3118796.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            22019..22579
                     /gene="efp"
                     /locus_tag="VQ860_000299"
     CDS             22019..22579
                     /gene="efp"
                     /locus_tag="VQ860_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET3118797.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            22601..22990
                     /locus_tag="VQ860_000300"
     CDS             22601..22990
                     /locus_tag="VQ860_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3118798.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            22983..23405
                     /gene="nusB"
                     /locus_tag="VQ860_000301"
     CDS             22983..23405
                     /gene="nusB"
                     /locus_tag="VQ860_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET3118799.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(23455..23691)
                     /locus_tag="VQ860_000302"
     CDS             complement(23455..23691)
                     /locus_tag="VQ860_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3118800.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(23704..24177)
                     /locus_tag="VQ860_000303"
     CDS             complement(23704..24177)
                     /locus_tag="VQ860_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118801.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(24195..24380)
                     /gene="briC"
                     /locus_tag="VQ860_000304"
     CDS             complement(24195..24380)
                     /gene="briC"
                     /locus_tag="VQ860_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET3118802.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(24539..25306)
                     /locus_tag="VQ860_000305"
     CDS             complement(24539..25306)
                     /locus_tag="VQ860_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET3118803.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(25303..26169)
                     /locus_tag="VQ860_000306"
     CDS             complement(25303..26169)
                     /locus_tag="VQ860_000306"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET3118804.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNVGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(26206..27573)
                     /gene="accC"
                     /locus_tag="VQ860_000307"
     CDS             complement(26206..27573)
                     /gene="accC"
                     /locus_tag="VQ860_000307"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET3118805.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(27585..28007)
                     /gene="fabZ"
                     /locus_tag="VQ860_000308"
     CDS             complement(27585..28007)
                     /gene="fabZ"
                     /locus_tag="VQ860_000308"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET3118806.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(28004..28489)
                     /locus_tag="VQ860_000309"
     CDS             complement(28004..28489)
                     /locus_tag="VQ860_000309"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET3118807.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPNPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(28492..29727)
                     /gene="fabF"
                     /locus_tag="VQ860_000310"
     CDS             complement(28492..29727)
                     /gene="fabF"
                     /locus_tag="VQ860_000310"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET3118808.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(29749..30480)
                     /gene="fabG"
                     /locus_tag="VQ860_000311"
     CDS             complement(29749..30480)
                     /gene="fabG"
                     /locus_tag="VQ860_000311"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET3118809.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(30514..31434)
                     /gene="fabD"
                     /locus_tag="VQ860_000312"
     CDS             complement(30514..31434)
                     /gene="fabD"
                     /locus_tag="VQ860_000312"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET3118810.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(31427..32401)
                     /gene="fabK"
                     /locus_tag="VQ860_000313"
     CDS             complement(31427..32401)
                     /gene="fabK"
                     /locus_tag="VQ860_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET3118811.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(32520..32744)
                     /locus_tag="VQ860_000314"
     CDS             complement(32520..32744)
                     /locus_tag="VQ860_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3118812.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(32804..33778)
                     /locus_tag="VQ860_000315"
     CDS             complement(32804..33778)
                     /locus_tag="VQ860_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET3118813.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(33778..34212)
                     /locus_tag="VQ860_000316"
     CDS             complement(33778..34212)
                     /locus_tag="VQ860_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3118814.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(34306..35091)
                     /locus_tag="VQ860_000317"
     CDS             complement(34306..35091)
                     /locus_tag="VQ860_000317"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET3118815.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            35416..36780
                     /locus_tag="VQ860_000318"
     CDS             35416..36780
                     /locus_tag="VQ860_000318"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET3118816.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            36783..37154
                     /locus_tag="VQ860_000319"
     CDS             36783..37154
                     /locus_tag="VQ860_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET3118817.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIARDKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            37368..38642
                     /gene="serS"
                     /locus_tag="VQ860_000320"
     CDS             37368..38642
                     /gene="serS"
                     /locus_tag="VQ860_000320"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET3118818.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLANYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(38667..39566)
                     /locus_tag="VQ860_000321"
     CDS             complement(38667..39566)
                     /locus_tag="VQ860_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET3118819.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPNWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(39676..40224)
                     /locus_tag="VQ860_000322"
     CDS             complement(39676..40224)
                     /locus_tag="VQ860_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET3118820.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(40442..41764)
                     /locus_tag="VQ860_000323"
     CDS             complement(40442..41764)
                     /locus_tag="VQ860_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET3118821.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSQVVIAETKKYFDK"
     regulatory      complement(41855..41943)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(42107..44443)
                     /locus_tag="VQ860_000324"
     CDS             complement(42107..44443)
                     /locus_tag="VQ860_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET3118822.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(44547..45095)
                     /locus_tag="VQ860_000325"
     CDS             complement(44547..45095)
                     /locus_tag="VQ860_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET3118823.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPVTTSWLKQIWVTNLIG"
     gene            complement(45092..45394)
                     /gene="zapA"
                     /locus_tag="VQ860_000326"
     CDS             complement(45092..45394)
                     /gene="zapA"
                     /locus_tag="VQ860_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET3118824.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            45481..46353
                     /locus_tag="VQ860_000327"
     CDS             45481..46353
                     /locus_tag="VQ860_000327"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET3118825.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNSISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            46365..46979
                     /gene="lepB"
                     /locus_tag="VQ860_000328"
     CDS             46365..46979
                     /gene="lepB"
                     /locus_tag="VQ860_000328"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET3118826.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            47107..49473
                     /locus_tag="VQ860_000329"
     CDS             47107..49473
                     /locus_tag="VQ860_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET3118827.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGFSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(49521..50804)
                     /locus_tag="VQ860_000330"
     CDS             complement(49521..50804)
                     /locus_tag="VQ860_000330"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET3118828.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(50965..51357)
                     /locus_tag="VQ860_000331"
     CDS             complement(50965..51357)
                     /locus_tag="VQ860_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3118829.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            complement(51656..52285)
                     /locus_tag="VQ860_000332"
     CDS             complement(51656..52285)
                     /locus_tag="VQ860_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3118830.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(52330..52569)
                     /locus_tag="VQ860_000333"
     CDS             complement(52330..52569)
                     /locus_tag="VQ860_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118831.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(52719..52985)
                     /locus_tag="VQ860_000334"
                     /pseudo
     CDS             complement(52719..52985)
                     /locus_tag="VQ860_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(53010..53321)
                     /locus_tag="VQ860_000335"
     CDS             complement(53010..53321)
                     /locus_tag="VQ860_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3118832.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(53246..53488)
                     /locus_tag="VQ860_000336"
     CDS             complement(53246..53488)
                     /locus_tag="VQ860_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3118833.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(53489..54121)
                     /locus_tag="VQ860_000337"
     CDS             complement(53489..54121)
                     /locus_tag="VQ860_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3118834.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(54135..55130)
                     /locus_tag="VQ860_000338"
     CDS             complement(54135..55130)
                     /locus_tag="VQ860_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3118835.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(55127..55825)
                     /locus_tag="VQ860_000339"
     CDS             complement(55127..55825)
                     /locus_tag="VQ860_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET3118836.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(55902..56912)
                     /locus_tag="VQ860_000340"
     CDS             complement(55902..56912)
                     /locus_tag="VQ860_000340"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET3118837.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(56896..57903)
                     /locus_tag="VQ860_000341"
     CDS             complement(56896..57903)
                     /locus_tag="VQ860_000341"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET3118838.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(57890..58843)
                     /gene="mvaD"
                     /locus_tag="VQ860_000342"
     CDS             complement(57890..58843)
                     /gene="mvaD"
                     /locus_tag="VQ860_000342"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET3118839.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(58825..59703)
                     /gene="mvk"
                     /locus_tag="VQ860_000343"
     CDS             complement(58825..59703)
                     /gene="mvk"
                     /locus_tag="VQ860_000343"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET3118840.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(59825..59947)
                     /locus_tag="VQ860_000344"
     CDS             complement(59825..59947)
                     /locus_tag="VQ860_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HET3118841.1"
                     /translation="MTTGWFQVNGRWYYAYSSGALAVNTIVDGYSVNYNGEWVR"
BASE COUNT        17736 a        13764 c        11257 g        17542 t
ORIGIN      
        1 gacagctcaa ccaagactgt ctcatcgctc ttaaacttct ttctgacccc aatcgtgaac
       61 aatttcaaca cgataatcgg caagtagaac taaaaatact ggctagacat attcatcgtc
      121 tcaagaaaaa acagtctgat tggaaagtac aatacactcg ttgtcttgat atcatctttc
      181 ctgagttgga taaaatcgtt ggaaagcatt cagaatatac ctaccaactc ttgacacgct
      241 accctaatcc tcagaaaagg cttgaggcaa gatttgataa gctgatagaa attaagcgat
      301 tgaccgcttc taaaattcag gatatcctct cagtcgcacc tcgttctatc ggaacaacat
      361 ctcctgctcg tgaattcgaa atcatcgaaa tcatcaaaca ttacaagagg ctcattgaca
      421 aggcggaaac atgtgtcaat gacttgatgg ctgagttcaa ctcggtcatc acgacggtta
      481 ctgggattgg gggtcgttta ggggcggtca ttttagccga gattcgaaat attcatgcct
      541 ttgataatcc tgctcaatta caagctttcg ctggactgga ttcttctatt tatcagtcag
      601 gtcagattga tttagctgga agaatgatca aacggggttc ccctcatctg cggtgggcac
      661 tcatacaagc tgccaaagca tgcgctcgct tttcacctgc ttttaaggcc tatcttaaga
      721 ctaagttaga ataaggaaaa cattacaatg tagccatcat ccaccttgca aaaaaactta
      781 tccgaaccct gttttatatc ctaaaaaaga gctgccattt gacgaacaaa aagtgatgta
      841 atttctgaaa ttaacacagg attacctttg aaaaaatgga ctttttcaag ggctttttgc
      901 cgtgctctaa aatcatcgcc aaatcatcaa attgaaataa gaaatagttt agataaaact
      961 attgactttt cttatagttt gtctttcttc tatcttccat tatatcatac tttttcagtc
     1021 tatggtagct ctctttaaaa ggctccgata ctgccgccac ctccgcctcc agagaagcca
     1081 ccgccagaac ttccacttcc agaagatacg gagtaggtac ttgctgtatt tgcgacacta
     1141 gcataatggc tcatttgcgc gcttgaatga taaaacatac tgtgccagcc ataagctaca
     1201 tagagattga tatctggatt ttcaacttga atctgatgaa ccttcatcaa atgactaacc
     1261 ttgtccgcat agccaaataa ggttgcatag accaagagac gattccaaac aacaatactt
     1321 tccaattcag ccttatccag tcgtgcaatc tcacgtaaca tattttcaaa actggtccag
     1381 agatagtaga cctcagctcc cgcttcattt agaacaccat cacgattatc tagtcgaagc
     1441 ttccaataat agaaaacaga caaaactaac cctagaaaac caagtattgg caaagggagg
     1501 taaagatagc catgaacgtc taaactgtac aagaacaaac caaatccgat aaataggggc
     1561 aagatagtca agacacccat acccacttgc aaagcctttt ccaaaccagt taaaggacga
     1621 tagtaatctg ggagccccca gaaggaaact cgttttctca ctccttcttg catctggttc
     1681 aatacctctt caaaagaaga tttgagttga agccctcttg cttgaatccg tttttcatca
     1741 gaaactttgg ctctacgata aagactatca gataccttgt aatccgcaaa caaattggaa
     1801 agagtttctt cttttttacc tgaaaaagct agatttaggc agtctttctc aaagcttgac
     1861 aaaccatctt cttttactag cctcaaacca actgcatctc cttctgaaat gatagagaca
     1921 ttcccacggt ctatcacatc tagcaaggta gcttgaataa gttgatcaaa ggtgaatttt
     1981 ccagctccct tgaccaaggg actcacttcc tccaaggagg tcgagtagac tgcttctgat
     2041 aaaaccatag gctctaattc cattgggggt tcatagagac gatgattttt agcatatttg
     2101 attgaaggag cggtctttct tctatagata aaatagaaac agatgctcaa taacaaggag
     2161 atggaaagga tcgaagggaa gatccaagta agtagttgtt tactttgatc tttttcttta
     2221 acgatcgaat cctctatctt attaaactct tctaaacgat tccctttcaa gccctgatcc
     2281 ctagcgctag caaaatcagt tcgcggccag taggcatgca attcaactcc acgcttagcc
     2341 ggaagattgt ctaaacgaat agtataatca aggttactct tttcaaccgt tctctctcta
     2401 aaaagtttcc ctgtatggaa aaagagtttc tcagccccct tgtctcccct tacatgaaat
     2461 tcaaactttt caatagactc tgaactatct gtcagaggtt gccaatttaa ttcagcgata
     2521 tcatcataaa ggaaaagtaa attttttaag ttccagacga ggtcaacttc aactatgtcg
     2581 ccctcctgac ctggattata gactctcaca gtataaccat ccgcttcttc tgttacttcg
     2641 ctagtcacat ctgctagttt tgcaccgttt ttcgcggcct gaatctttgg atgagggtca
     2701 atgtcaaacc cgctaggcat cttaccagca cgtccaagtc ccacgatttg gcccttaaag
     2761 tcctcctcaa actggtaaac tatcttctgt ctaaactctg ccgtattgtc tgcatgaata
     2821 tacaaatccc cttgataaga gtttatcttg aaatcaatgg caaaaacaga gagtggaaga
     2881 aggcaaaaca agcctaacac cagtaagaaa aaagtttttt tcatcaacta agcccccttt
     2941 ttatctttct tatcattata gcattttttc gtaagtaaag gcttacttat gttgaaaaat
     3001 tacgcatttt tcgataaaat aggagacagt tattttttaa tagatcagaa taggagaaat
     3061 catgagaaaa atatacttat ctattttcac aagtctcttg ctgatgctag gacttgtcaa
     3121 tgttgctcaa gccgatgaat atttacgcat cggtatggaa gcagcatatg ctccctttaa
     3181 ctggacccag gatgatgata gcaacggagc tgtcaaaatc gatgggacca atcagtatgc
     3241 caacggatac gatgttcaaa tcgccaagaa aatcgctaag gacttaggta aagaaccttt
     3301 ggttgttaaa accaagtggg aaggtctagt ccctgccctt acttctggta agattgacat
     3361 gattatcgca ggtatgagtc caactgcaga acgcaaacaa gaaattacct tttcgagcag
     3421 ttactatact agcgaaccag ttttgcttgt caaaaaagat tctgcctacg caagtgctaa
     3481 atctttggat gactttaacg gtgcaaaaat cacttctcaa caaggggtct acctttataa
     3541 cttgattgca caaatcccag gtgctaaaaa agaaacagcc atgggagact tcgctcaaat
     3601 gcgacaagct cttgaggctg gtgtcattga tgcttatgtt tctgaacgtc cagaagcact
     3661 gactgctgaa gctgcgaact ctaagttcaa gatgattcaa gtagaacctg gtttcaaaac
     3721 tggggaagaa gatacagcta tcgctattgg gcttcgtaaa aatgacaatc gtattagcca
     3781 aatcaatgcc agcattgaaa ccatttcaaa agatgaccaa gttgccttga tggatcgtat
     3841 gatcaaggaa caacctgccg aagctacaac aactgaagag actagcagta gtttctttag
     3901 ccaagttgct aaaattcttt ctgaaaactg gcaacaactc ttgcgtggtg ctggtatcac
     3961 tcttttaatc tctatcgtcg gaaccatcat aggtctcatt attggacttg ccattggtgt
     4021 cttccgtact gctcctctct ctgaaaacaa agtcatttac ggcctacaaa aactagtcgg
     4081 ctgggttctc aatgtctaca ttgaaatttt ccgtggtacg ccaatgattg ttcaatcgat
     4141 ggttatctac tatggaactg cccaagcttt cgggatcaac cttgaccgta cactggctgc
     4201 tatcttcatc gtttcaatca ataccggtgc ctacatgact gaaatcgtcc gtggtggtat
     4261 cctagcagtt gacaagggac aatttgaagc tgcgactgct cttggtatga cccataacca
     4321 gaccatgcgt aagattgtcc tacctcaggt agtccgtaac atcctacctg caactggtaa
     4381 tgaatttgtc atcaatatca aagatacatc tgtattgaac gttatctctg ttgtcgaact
     4441 ttatttctca ggaaataccg tggcaacaca aacctatcaa tacttccaga catttacaat
     4501 catcgccgtg atttactttg tcctcacctt caccgtaaca cgtatcctac gctttatcga
     4561 gcgcagaatg gacatggata cctacactac aggtgctaac caaatgcaaa cggaggattt
     4621 gaaataatga cacaagcaat ccttgaaatt aaacacctca aaaaatccta tggacaaaac
     4681 gaagtgctaa aagacatttc actcactgtc cacaagggag aggtcatctc tatcatcgga
     4741 agctctggaa gcggaaaatc gaccttccta cgctccatta acctacttga aacaccaact
     4801 gatggacaaa tcctttatca tggacaaaac gtcctcgaaa aaggctatga cctcacgcaa
     4861 taccgtgaaa agttggggat ggttttccaa tcctttaacc tctttgaaaa tctcaatgtt
     4921 cttgaaaaca caatcgtcgc tcagacaact gtcctaaaac gcgaacgcac agaagctgaa
     4981 aagattgcca aagaaaacct ggaaaaggtc ggcatgggag aacgctactg gcaagccaaa
     5041 ccaaaacaac tctcaggtgg tcaaaaacaa cgtgtggcca tcgctcgtgc cctctccatg
     5101 aatccggacg ctattctctt tgatgaacca acatcagctc tcgatccaga aatggttgga
     5161 gaagtcctca aaatcatgca ggacctggct caggaaggct tgaccatgat tgtcgtaacc
     5221 catgaaatgg aatttgcccg tgatgtctct caccgtgtta tctttatgga taagggcgtg
     5281 atcgctgaag aaggtaaacc agaagacctc ttcaccaatc ctaaagaaga ccgaacaaaa
     5341 gagttccttc aacgctatct caaataaaaa gaaaaggctg catcaaccgt gcagtctttt
     5401 tgctgtcctc aaaatgaaaa ggcagattct ctatctctac tacttgaagg tcaagaatcc
     5461 gccgttatcc aaagattaat cttcaaattt ttcataattt ttttcataga aatcaattag
     5521 gcctagggct gtttcaaatg aaatattttt tacttttgca cgaccctgcg ccagagcaat
     5581 gatagacatt tcacgcgcat tcgtttcttt agagatacgg tagcctgtga ttttcttatc
     5641 acgaacccag ccaacaactg attctacttt ttcaaagttt gacttagcca tgtttttctc
     5701 ctattttctt ctttataata tttaattgta tacgttttta ctacttttgt caataaaaaa
     5761 aacatatatt caacgaaaat aattagttca gaattttctt acttcctttt taaatccgat
     5821 aatatatagg ttttgctagc ctctacacca taaatatttg ctaataaaaa tactgtatta
     5881 ttaccctctt aaggtgcgaa attattcaag ttcttaaaaa atgcttctct atttccgtaa
     5941 gatagcttat ttcttcgatt taagaactga agatgatagt tctaaccttt agaaatccaa
     6001 gccttcacta gctcaaaaac tcctatcttt cttcctcaat aaatcatctg agagataggt
     6061 attccttatg tccttaaaat tcatcactcc tttggatatt gaggtgctag cctagaagca
     6121 gacacccgat tatctaaacc atccttaata gagatgacaa gacagataag ctcagttaat
     6181 tacttatata tctttttaat atggtatatt tgtcaacaaa aagaaatcaa atcatacctt
     6241 atactcaatg aaaatcaaag agcaaactag gaagctagcc gcaagttgct caaaacactg
     6301 ttttgaggtt gcagatagag ctaacgtggt ttgaagagat tttcgaagag tattaaagac
     6361 agtgtgacta tgcttgtcaa tagataggaa atcaaaatga aggatggaaa tctgagccaa
     6421 acatcataag tgctataatg aacagaagta agaattgcac gataagtttt ctaaaaccat
     6481 aggaatcgtc ccctttcttc atcttcatta tagcacatat acatcagttg tacaaataat
     6541 atgatatttt tttattagtc ctcagacaag catattataa agcgtttcat taccatttaa
     6601 gttaatataa gctggatcaa aaccttccat tctacgaatc aaacctgcat aatcatgctt
     6661 atctgctaaa gcgatcccaa ttaatactgg gcctgttccc ttgctagctc gtttgatata
     6721 ctcaaaacgt gtgatatcat catttggccc caggatatca tttacaaact cacgcaaagc
     6781 tcctggacgt tgtgggaaat tgaccacaaa gtaatgtttg ataccatcat aaatcaaggc
     6841 acgctcttcc atttctggca tacggttgat atcattattt cctccagaaa tgatacaaca
     6901 aatggttttc cccttaatat attcagctaa aacctctaaa gaggcgatac tagccgctcc
     6961 agcaggttct gcgactatcc cttgcttaga gtaaaggtca atcaaggttt cagaaatcaa
     7021 tccctcatcg acacctacca aagttttaat atgttgacga gttgcttcat aggtcaactg
     7081 acctaccttt tgcacagcaa tcccatcagc aaatttatca atttccttga gtttgactgg
     7141 acctccagcc tcaaaggcag ctttcatgga acgcgctcca ttcgcctcta ctccgataac
     7201 ctcaatctct ggacttgttt ccttgatata ggtagaaacc ccggcaatga gaccgccacc
     7261 accaacagga accaagacag catcaaaatc aatcgattct tttcgagctt cttctaaaat
     7321 ctcataagca actgttcctt gacctgcttg aacatgagca tcatcaaaag gatcaataaa
     7381 ggtacgattt tcagagactg taaattcttg agctgctttg gctgaggcat caaaggtatc
     7441 tccaactagt ttaatagtta caaaatcccc accaaaaaag cgaacctgac caatcttttg
     7501 ttgtggcgta gtaatgggca taaagatagt agcaggaatt ttcatttcat tacaagtata
     7561 ggctactccc tgcgcatgat ttcccgcaga agcgcagact accccacgtt cacgttcttc
     7621 cttgctgagc tgggaaatgg cataataggc accacgaatt ttaaaggagc gaacacgctg
     7681 ggcattttct tttttcaaat aaatcttagc accatacttc tccgataaat aatgatcgta
     7741 atccagtgga gtattcacaa ccacaccgtt caagaccttg tgagccttga ttatatcttt
     7801 tgaacttaac atataaaacc tctttttcta taaaaaacag tcactaatga ctgtttttta
     7861 gttattcatc tccgaaaact tcagtaacac tttcatggta tttatgagcc atacgaatcg
     7921 aaaactcttt aggaagttca taacgatttg tggaaatcca atcatataac cattctacca
     7981 aactttcttc actatcatta cgatggaaga taaaatagtt taaaatttct ttatattcta
     8041 catcattcaa atccaacgtg tctacaaatt gactacgagg aacaaaatta gaatctaatt
     8101 ttcttagttg atctgtcaat tctcccaatt gtaaatccaa ctgaaaaaat agtttttgca
     8161 gttgcctatc agtttcatca catcctgtct tgatagaaaa caaattggta atattcatat
     8221 gatttcaacc cctaaataag tacatctaat atcccacgaa tagctgaagc taaagttttc
     8281 gcagtccagt catttaaacc cgattctttc aatccagatg caataatttg ctctatttga
     8341 tataaatcgc catctatcgt ctcatttatt ctgcgaagag gaccttcaat ataggataaa
     8401 gcttctccga atctaacagc tgatttaggt cctaatgatt taccaactat atttgttaat
     8461 gttttttatt tctcaaaatc catttcgcta tataacgagc agatttagtc gcatcagctc
     8521 tctcaaacgg agaatgaatt tcaagacctt cttctctagc tatttgtgcc aatttgaaga
     8581 attgttcaaa ggtcatatgc aacctaccat cttcaaaatt agcatcatca taaatgttaa
     8641 ttacagcatt ttcatcatac gaccaatctg ctttattttg gtctgctagc actattaccg
     8701 acggtgtaat tacattatac aactagaacc aataataacg atgcaatttt tctcataatc
     8761 tttttcataa aatcatctcc agcgctatat atttctaatt agttatagat tttgaatgca
     8821 tcatcgtcgt ttttaccaac gaatggcatt gctttacgca attctgcacc aactttttca
     8881 atttcaaggt tagctgcttg ttcacggtaa gcagtcaatt ttggacgtcc agctttatag
     8941 tcatttacaa agtcatttgc aaacttacca ttttggatgt ctgccaagac agccttcata
     9001 ttttctttaa cttgttcagt gattacacgt ggacctgata catagtcacc gtattcagca
     9061 gtgtttgaaa tagactgacg cattttcttg aatccacctt cgtagatcaa gtcaacgatc
     9121 aatttcattt cgtgaagaac ttcaaagtaa gccaattctg gagcgtaacc tgcttctgtc
     9181 aagacttcga aacctgcttc gataagggca gtcaaaccac cacaaagtac agcttgttca
     9241 ccaaacaaat cttcttcagt ttcttctttg taagttgttt caagaagacc tacacgagcc
     9301 gctccaacac ctttacacca gtccatagca atgtttttag catttcctgt tgcatcttgg
     9361 tatactgcat aaagagctgg aacaccaaat ccttcttcgt aagtacgacg taccaagtgt
     9421 cctggtcctt taggagcaca catgaagaca tctacatccg caggaacttt gataaattca
     9481 aagtggatgt tgaaaccatg ggcaaatcca actgcgtttc cagcttccaa gtttggagcg
     9541 atttctgctt cgtacaattc ttgttgaatt tcgtctggcg ccaagatcat gataacatca
     9601 gccaacttag tagcttctgc tactgtgtaa gtatcaaatc catcttcttt tgctttatca
     9661 aaagatttac ctggacgtac accgataata acgtcacgac cggaatcacg caagttttga
     9721 gcatgcgcat gcccttgtga accataaccg ataacggcga tttttttacc gtcaagtgct
     9781 gctactttaa catctttttc atattccatt tgaactgtca tagcttttct ctcttttcta
     9841 ttatttattg ccttttaggc tggtttaata aatttaagtt ggatttttaa tcgcgggtaa
     9901 atccagttgc acccgttcga gcaatattgc gaataccgta tgggcgaatg actcgcaata
     9961 gggcttcgct cttttctgca tttcccgtca tctgaatggt aatcgagctt ggcgctacgt
    10021 ctaccactgt tgcacggaaa ggttgaataa tcgctaaaat ctcagctctc ttctcagctg
    10081 gcgctgacat cttaaccaaa atcacctcgc gctccaaatg aggcttgtct gtaatatctc
    10141 gaatgcgaat cacatcaatc tgacgattga gctgtttgat gatttgctcc acttcatcat
    10201 gagaagcaac atcaataata atagtgatac gcgatacatt cggatcttct gttgctccaa
    10261 cagagatgct ttcaatatta acctgacgac gagataggac acctgtaaag cgattgagta
    10321 ctcctgaacg attttgtagt tttgctgtta acattctacg catggaactt cacccccaac
    10381 atctcatgat tactcttacc agccggtacc attggtaaca cctgttcctt acgagaaata
    10441 tctacctcaa ttagcatagg aacatcctca gtgatgactt caaggtcttg agccaaggtc
    10501 tcaggattgt caaacttata gtttttaata ccataagcct gcgccatcaa ttggaaatca
    10561 ggaagggtat caaagaccga ctctgatgtt ctgccttcat agaaggattc ctgccactgg
    10621 cgaaccattc caagtgaatg attgttcagc ataaccacct tgattggcac cttgtaaata
    10681 ttcaaaatag ccaactcctg gttggtcatt tggaaaccac catccccaac aaacaagact
    10741 acttccttat ctgggttagc aattttagca ccgattgctg ctggaattcc aaagcccatt
    10801 gttcccaaac cacctgaagt cactaactga cgctcatttt ggtagggata atactgagct
    10861 gtccacattt ggtgttgacc aacgtctgtt accacaatgg catctccatt cgtcaattca
    10921 ccaattcgtt caataactgc ttgcggttga accacacgct ctttcttgtc ataagaacga
    10981 acacgattct tgtctttagt gactttctca atccactttt cagtattgtt gtgaactgtt
    11041 ggttctgcta gcaacatttg caaggccttc ttagcatctc caactacagg aatgtctgca
    11101 ctgataatct tgccaatctc agctgggtca atatcaatgt gggcaacctt agcattctta
    11161 gcgaaagtct taggattccc cgtcaaacgg tcatcgaaac gagaaccaat actaatcata
    11221 aagtccgctt ccgtcatggc aatatttgct gcgaatgacc cgtgcatgcc tcccattcca
    11281 agaaagagtg ggtgactcgt tgcaatcgtt ccttgtccca aaagactggt taccactgga
    11341 atttgatagc gttctgcaaa ttcatttagt tccgtagcag cctcagcata actaattcca
    11401 ccaccagcta acaagactgg ctttttagcc ttggacaatt gcttcaagat tttcttgatt
    11461 tgcatatcat tcggctcaag agtcggctga taacttggta aattcacttc tggtgaataa
    11521 atgaagtctg tttctaaagc agatatgtct tttggtaggt caattacaac tggccctgga
    11581 cggcctgtag ttgcgatatg gacagcttcc gtaatgatac gcggaatatc agctgtctca
    11641 cgaacttggt aattgtactt agtgattggc atggtaattc ccacgatgtc tgcctcctga
    11701 aaggcatcct tcccaatccc tgctcgcgcc acctgacctg taaagaccaa aaggggaacg
    11761 ctatcgctca tggcatccgc aatccctgta atggcatttg ttgctcctgg tccactagtg
    11821 acgacggcaa cacccaactt tccagttgat ttggcataac cttcagcttc atgcaaacaa
    11881 ccttgctcat ggcgccctag aatgtggcga atgcctttaa aattatatat cgcatcataa
    11941 aaaggcaaaa ccgcaccacc aggataacca aagatggtat caactcctaa atcacgaagt
    12001 gtttccaaaa ctaggtccga ccccgtctta ggagattcta aactgatttt ctccattatt
    12061 cccctttctt tcctcttaaa aataacttgt tactatcata ccattttttc aaaatttttc
    12121 aagataaaag aagaaatttt ctgaattttc tattttaacg tttatttatg aatgttattt
    12181 ttgtttttat taaaaagata ccgatttcat ttactaaaaa agaaaaaaga actgatttct
    12241 cagtccttca ttaatcttat tccacactaa ataggtatgg gtaaacaggt tgttgacctt
    12301 ggtgaatctc gacttcaacg tcttcgaatt cttctacgat ttcttgagcg atttcattgg
    12361 caagttcttc gcttccgtct tcaccgacat agaaggttac gatttcactg tcttcatcca
    12421 acatatgttt caaggtttca gtcaatgttt ggtgcatatc agggtttgac acaagaattt
    12481 ttccatccac catacctaga ttatcgtttt catggatttc taagccatcg atcgttgtat
    12541 cacgcacggc tgttgtgacg cttccgctaa caacatcgct aagagcagct gtcatacgct
    12601 cttggttttc ttcaatggac ttgcttggat caaaggcaag aagacttgtc ataccttgag
    12661 gaagagtgcg agcctctacc actactgctg gttgctccaa aacttctgcc gcagattgag
    12721 ctgccatgaa gatgttcttg ttgtttggca agaagatgat gttacgggca ttgacctgtt
    12781 caacagcctt gataaagtct tctgttgaag ggttcatggt ttgaccgcct tcgataacat
    12841 aatccacgcc ttgagaacag aagatatctg ctagaccttt accagccacc acagcaatca
    12901 aagcatactc tttttcttca gccgacttga taacttgagt agcttctttc tcaacctgtg
    12961 cttcgtgttg gttacgcata ttgtcaactt ttaccttgac caagctacca tatttgagac
    13021 cttcttgcat aacaagtcct ggatcttctg tatgaacatg gactttgaca atttcatcat
    13081 cgttaacaac gaggagagaa tccccaagct catccaagta gttacggaat tcatcgtagt
    13141 caaaatcttt agcataggtt ggaccttgct taagagctac catgatttca gtacagtaac
    13201 caaacgtgat gtcctcagtc gctacgtgac cagctacaga cttatgatgc tctacattga
    13261 tcatctcact catgttggca ggagtcgcta caaagtcctc agatgcaata tattcgccag
    13321 taagggctga aaggaaacct tcgtagatga agaccaatcc ttgaccacct gagtccacaa
    13381 cgccaacttc tttcaatact ggaagcatgt ctggtgtttt agctagagct gttttagcac
    13441 cttccaaggc tgcgcgcatg acttcaacag cgtcatctgt ttgctcagct tttttcttag
    13501 caccgatagc agctccacga gaaactgtta aaatcgttcc ttcaacaggt ttcatcactg
    13561 ccttataggc aacttccaca cctgattgga aggccagagc caagtcttga cctgttaact
    13621 cgtctttatc cttgatagct tgggaaaatc cacggaaaag ctgagacgta atcactcctg
    13681 agttcccacg cgcacccatc aaaagccctt tggcaagaat gctcgctact tctccaactg
    13741 tagaagctgg cttgtctgca acttctttag caccattttc aatggtcatt cccatatttg
    13801 tcccagtatc tccatctggg actggaaaga cgtttaatga attgacatat tcagcttgct
    13861 tattcaagcg agttgatgca gcctgcacca tttcttgaaa taagctagta gtaatttttg
    13921 acacggttat tctcctacaa ctttgatatt ttgaatgtag acatttacag tctgagcagt
    13981 aattccaagc tggttttcca agctaaaggc aacacgctct tgaatgtttt ttgacacttc
    14041 actaatcttt gttccgtagc ttaacacggt atatacatca actgcaatac tgccatcttc
    14101 ggctgccttt acgacgacac ctttagaata attttcctta cctagcaggg cttggaaatt
    14161 atctttgagg gcatttttac tagccatacc gaccacacca aaaatctcag ttgctgctcc
    14221 acctacgacg gttgcaatca cttcatctgt tagttcgatt tgaccatctt ttgtattaat
    14281 ttttacagtc atccttttta cctcaactag ttgatactct attttatcat atttcagccc
    14341 aagtgtaaaa gcagaatgat gtatcagcgg atatttactc tatttttcaa acgatgttat
    14401 acccacaata aaagaaaaaa gaccctaagg tctcctttgc ttttattatt aaacgcgttc
    14461 aactttacct gatttcaaag cacgagctga agcccaaact tttttaggtt taccatcgat
    14521 aagaacagta actttttgaa ggtttggttt tacggcacgt tttgtttggt tcatcgcgtg
    14581 tgaacggttg tttcctgata cagtcttacg acctgtaaag taacatactt tagccattgt
    14641 gttttcctcc tattagatct aatatagcgg atgtgctagc accacatacc gtactatgtt
    14701 atcacacttt cttgtttttt gcaagggaat tggaagattt tttatttgtg tcttaaatca
    14761 ggtcttgcgt gacattttct gctctccaca tgccattgtt gattaacaga acaccagaat
    14821 taaaattatg tgtataaaaa tcatctctaa ctgcagctaa gggtatagcc gtcaagtcca
    14881 aatcccacag ctcatctatc gattttctta caacaatatc tgaatccaaa tacagtacac
    14941 gagactcgct tacatacttt ggaataaaat acctaaaaaa agccgcatat gaaagtccct
    15001 caaaggggag acgataacct ttcagaatac tactgtcaat ctgaacattc acaatctcac
    15061 tattcaaagt ctctagtctt ttttccatca attggaacca ttctcgcgga aggtcatcat
    15121 taaaaacata aaacttaaga ttataatgat gaacacaaag agattttatt gttgtttcaa
    15181 ctttatccat ataagcatta tctgcaccta agacaatcgc ttttttctct tctttcactc
    15241 tttatcttat ttctttttat tcccatcata ttattcccat catatgtttc tacgtaacca
    15301 ttattttcgc ctattcgttc gtaaaaccat accagtggag attttagatg aagtcccatt
    15361 acggtttaca ttttttacat tacgacacgg agttttacaa atcgatttca tttgccaaac
    15421 gtagttagtg aggcagttag ctagttcgcc aaatagcgac tagcgtccaa caatttggaa
    15481 ctttagttcc aattgttggt actgagtcac atcttctcct ctaactctac gtctggatac
    15541 ttgtccgcaa accagcggag ggcaaagtca ttttcaaaga gaaagactgg ttggtcaaaa
    15601 cggtctttgg ctaagatatt gcgacttgac gacatccgtt catccaagtc ctcaggcttg
    15661 atccaacgaa cggtcttttt acccattggg ttcataacta cttccgcatt gtactcgctt
    15721 tccatgcggt gtttaaagac ttcaaactgg agttgaccta cagcgcctag catgtactca
    15781 cctgtttggt aattcttata aagctgaacg gctccttctt gcaccaattg ctcaatcccc
    15841 ttgtggaagg atttttgctt cataacattc ttagcagaaa ctttcatgaa aatttcagga
    15901 gtaaaggttg gcagtggttc aaattcaaac ttgttttttc caaccgtcaa ggtatcccca
    15961 acctgataag taccggtatc gtaaaccccg ataatatcac ctgccacggc attggtcaca
    16021 ttctcacgac tctccgccat aaactgggta acattagata gtttggcacc cttaccagta
    16081 cgagggagat tgacactcat gccacgctca aattcgcctg atacgatacg gacaaaggca
    16141 atacggtcac ggtgacgagg atccatgttg gcttggattt taaagacaaa gcctgagaaa
    16201 tccttgtcat aaggatccac aatttcaccg tctgttttct tgtgaccatg tggttctgga
    16261 gcaaacttga ggaagatttc aaggaaggtc tgcacaccaa agtttgtcag ggctgaaccg
    16321 aaaaagacag gcgtcaattc tccagccaga atagcttcct ctgaaaactc attcccagct
    16381 tcatttaaaa gctcaatgtc atccttgact tgctcgtaga aaggattgct accaaaaagt
    16441 ttgtctccat cttctaggct agcaaaacgc tcatcccctt tgtaaagctc taaacgttgg
    16501 ttatagaggt catacaagcc ctcaaaggct ttccccatcc cgataggcca gttcataggg
    16561 tagctagcaa tgcccaagat ttcttccaat tcttgcaaga gatccaaagg ctcacgaccg
    16621 tcacgatcca acttgttcat aaaggtaaag actggaatgc cacgatgttt cacaacctca
    16681 aacaatttct ttgtttgagc ctcgatcccc ttggcagagt ccacgaccat gaccgcagca
    16741 tccaccgcca tcaaggtacg ataggtatct tctgagaagt cctcgtgccc tggcgtgtct
    16801 aagatattca cgcgcttgcc gtcgtagtca aattgcataa cagatgaagt aacagaaatc
    16861 ccacgttgct tctcgatatc catccagtca gatttagcaa aagtccctgt tttcttccct
    16921 tttaccgtac cagcatcacg aatctcaccc ccaaagtaga gtaactgctc agtgatggtt
    16981 gttttccccg cgtccgggtg ggagataatg gcaaaggtac gacgtttctt aatttcttct
    17041 tgaatattca taagttctct ttctttgatt ctctattttt cttgtttcaa tagctgagaa
    17101 tgatttttac attggatttt accattcctt tcgacactcc attatatcgg attttagcat
    17161 ttttttcaat ttctatttct tttcacttcc ccctccctta tttataggaa aatatggtaa
    17221 aatagaacag actaaaaatc atcatttcac gaaaggatgc aagatgaaaa ttacgcaaga
    17281 agaggtaaca cacgttgcca atctttcaaa attaagattc tctgaaaaag aaactgctgc
    17341 ctttgcgacc accttgtcta agattgttga catggttgaa ttgctgggcg aagttgacac
    17401 aactggtgtc gcacctacta cgactatggc tgaccgcaag actgtactcc gccctgatgt
    17461 ggccgaagaa ggaacagacc gtgatcgctt gtttaaaaac gtacctgaac aagacaacta
    17521 ctatatcaag gtgccagcta tcctagacga tggaggagat gcctaatgac ttttaacaat
    17581 aaaactattg aagagttgca caatctcctt gtctctaagg aaatttctgc aacagaattg
    17641 acccaagcaa cacttgaaaa tatcaagtct cgtgaggaag ccctcaattc atttgtcacc
    17701 atcgctgagg agcaagctct tgttcaagct aaagccattg atgaagctgg aattgatgct
    17761 gacaatgtcc tttcaggaat tccacttgct gttaaggata acatctctac agacggtatt
    17821 ctcacaactg ctgcctcaaa aatgctctac aactatgagc caatctttga tgcgacagct
    17881 gttgccaatg caaaaaccaa aggcatgatt gtcgttggaa agaccaacat ggacgaattt
    17941 gctatgggtg gttcaggtga aacttcacac tacggagcaa ctaaaaacgc ttgggaccac
    18001 agcaaggttc ctggtgggtc atcaagtggt tctgccgcag ctgtagcctc aggacaagtt
    18061 cgcttgtcac ttggttctga tactggtggt tccatccgcc aacctgctgc cttcaacgga
    18121 atcgttggtc tcaaaccaac ctacggaaca gtttcacgtt tcggtctcat tgcctttggt
    18181 agctcattag accagattgg accttttgct cctactgtta aggaaaatgc cctcttgctc
    18241 aacgctattg ccagcgaaga tgctaaagac tctacttctg ctcctgtccg catcgccgac
    18301 tttacttcaa aaatcggcca agacatcaag ggtatgaaaa tcgctttgcc taaggaatac
    18361 ctcggtgaag gaattaaccc agaggttaag gaaaccattc taaatgccgc taaacacttt
    18421 gaaaaattgg gtgctattgt cgaagaagtc agccttcctc actctaaata cggagttgcc
    18481 gtatactaca tcatcgcttc atcagaagct tcatcaaact tgcaacgctt cgacggtatc
    18541 cgttacggct atcgcgcaga agatgcaacc aaccttgatg aaatctatgt aaacagccga
    18601 agccaaggtt ttggtgaaga agtgaagcgc cgtatcatgc tgggtacttt cagtctttca
    18661 tcaggttact acgatgccta ctataagaag gctggacagg tccgtacact tatcattcaa
    18721 gatttcgaaa aagtcttcgc ggattacgat ttgattttgg gtccaactgc tccaagtgtt
    18781 gcctatgact tggattctct caaccatgac ccagttgcca tgtacttagc cgacctattg
    18841 accatacctg taaacttggc aggactgcct ggaatttcga ttcctgctgg attctctcaa
    18901 ggtctacctg tcggactcca attgattggt cccaagtact ctgaggaaac catttaccaa
    18961 gctgctgctg cttttgaagc aacaacagac taccacaaac aacaacccgt gatttttgga
    19021 ggtgacaact aatgaacttt gaaacagtca tcggacttga agtccacgta gagctcaaca
    19081 ccaattcaaa aatcttctca cctacttctg cccactttgg aaatgaccaa aatgccaaca
    19141 ctaacgtgat tgactggtct ttcccaggag ttctaccagt tctcaataaa ggggttgttg
    19201 atgccggtat caaggctgct cttgccctca acatggacat ccacaaaaag atgcactttg
    19261 accgcaagaa ctacttctat cctgataacc ccaaagccta ccaaatttct caatttgatg
    19321 aaccaatcgg atataatggc tggattgaag tcaaactaga agacggtacg accaagaaaa
    19381 tcggtatcga acgtgcccac ctagaggaag acgctggtaa aaacacccat ggtacagatg
    19441 gctactctta tgttgacctc aaccgccaag gggttccctt gattgagatt gtatctgagg
    19501 cagatatgcg ttctcctgaa gaagcctatg cttatctgac agccctcaag gaagttatcc
    19561 agtacgctgg catttctgac gttaagatgg aggaaggttc gatgcgtgtg gatgccaaca
    19621 tctcccttcg tccttatggt caagagaaat tcggtaccaa gactgaattg aagaacctca
    19681 actccttctc aaacgttcgc aaggggcttg aatacgaaat ccaacgtcaa gctgaaatac
    19741 ttcgctcagg tggtcaaatt cgccaagaaa cacgccgtta cgatgaagct aacaaaacaa
    19801 ccatcctcat gcgtgtcaag gaaggggctg cagactaccg ctacttccca gaaccagacc
    19861 tacccctctt tgaaatttct gacgagtgga ttgaggaaat gcggactgag ttgccagagt
    19921 ttccaaaaga acgtcgtgcg cgttatgtat ctgaccttgg tttatcagac tacgatgcta
    19981 atcagttgac tgctaataaa gtcacttctg acttctttga aaaagctgtt gccctaggtg
    20041 gtgatgccaa acaagtctct aactggctcc aaggggaagt cgctcagttc ttgaatgctg
    20101 aaggtaaaac actggaacaa atcgaattga caccagaaaa cttggttgaa atgattacca
    20161 tcatcgaaga cggtactatt tcatctaaga ttgccaagaa agtctttgtc catctagcta
    20221 aaaatggcgg tggcgcgcgt gaatacgtgg aaaaagcagg tatggttcaa atttcagatc
    20281 cagctatctt gatcccaatc atccaccaag tctttgccga taacgaagct gctgttgccg
    20341 acttcaagtc aggcaaacgt aacgccgaca aggcctttac aggattcctt atgaaggcaa
    20401 ccaaaggcca agccaaccca caagttgccc ttaaactact tgcacaggaa ttggcgaagt
    20461 tgaaagaaaa ctagacagaa caaaaccagc cctaaggttg gttttttctt gacaaataga
    20521 aagaaaacgt ttacaatatt gcgtgtaaag tttccaaaca agaaaactaa aaatcgcaac
    20581 aataaggagt tatttatatg gctacaatga aggcagctcg ctggcatgca gcgaaagatg
    20641 ttcgtattca agaaatagaa gttcctgaag tacttccgca ccaagtaaaa gttgcagtta
    20701 agttcacagg aatttgtggt actgacctcc atgaattttt agatggacct atctttatcc
    20761 caacagatga gcacgtctat tctggtcaaa aagcaccggt aacactggga catgaatttt
    20821 ctggtgaaat catagaagtc ggaagcgatg ttacccgtgt taaagttggt gatcgtgttg
    20881 ctgtggaacc aattctagct aaaaataact tagttggtga ttataatttg gatccaaacc
    20941 ttaattttgt cggtttggct gcagacggtg gatttgccaa atattgtgtt ttagacggtg
    21001 acttagtaca tgtcattcca gatagcttga gctatgaaca agctgctctt actgaacccg
    21061 ctgctgttgc agtctatgct gttcgtcaat cttctttgaa ggctggcgat acagctgttg
    21121 tctttggttt aggcccgatt ggtctattaa ttgtagaagc tcttcgtgca gctggtgctt
    21181 ctaagattta tgctgttgaa ctatcacctg aacgtcaagc aaaagctgaa gagttaggag
    21241 ctatcgttgt ccgtccggaa gaaggtgaaa cagctgttga agctattcat cgtttaacaa
    21301 acggtggtgt agatgtttct tatgaagtaa cgggtgtgcc agtagtttta ggacaagcct
    21361 tagctgccgt acataaagca ggtgagtgca tggtggtctc tatctgggaa cgagaagcaa
    21421 atattaatcc gaatgaattt gcaatccaag aaaagacact aaaaggaatc atcgcttatc
    21481 gtcatatctt ccctaaagta ttagaattga tggaacaagg ctacttctct gctgaaaaat
    21541 tagttactaa gaaaattaaa ttggaaaata tcgtcgaaga aggctttatc gaattaactc
    21601 aagataagtc acaaattaaa attttggtag aaccagaata aaaaatcaat ctttttaaga
    21661 caatactaac aggtcggagt aaacttactt cggccttttg aaatataata ctcttcgaaa
    21721 atctcttcaa accacgtcag cgtcacatta ccgtatatat ggttactgac ttcgtcagtt
    21781 ctatccacaa cctcaaaaca gtgttttgag cagcctgcgg ctagcttcct agtttgctct
    21841 ttgatttcca ttgagtatga gaagaaatat agtggatact ctttaacatt aaccactcca
    21901 cctgactagc caatattctt tttcgctcct accaactccc aataactatt ttggctttat
    21961 ttccagagta ttttatggta aaatgaagag taataatatt tgttaaagag gtaaaaacat
    22021 gattgaagca agtaaattaa aagctggtat gacctttgaa acagctgacg gcaaattgat
    22081 tcgcgttttg gaagctagtc accacaaacc aggtaaagga aacacgatca tgcgtatgaa
    22141 attgcgtgat gtccgtactg gttctacatt tgacacaagc taccgtccag aggaaaaatt
    22201 tgaacaagct attatcgaga ctgtcccagc tcaatacttg tacaaaatgg atgacacagc
    22261 atacttcatg aatacagaaa cttacgacca gtacgaaatc cctgtagtca atgttgaaaa
    22321 cgaattgctt tacatccttg aaaactctga tgtgaaaatc caattctacg gaactgaagt
    22381 gatcggtgtc accgttccta ctactgttga gttgacagtt gctgaaactc aaccatctat
    22441 caaaggtgct actgttacag gttctggtaa accagcaacg atggaaactg gacttgtcgt
    22501 aaacgttcca gacttcatcg aagcaggaca aaaactcgtt atcaacactg cagaaggaac
    22561 ttacgtttct cgtgcctaat ctctagaaag aggtcattct atgggaattg aagaacaact
    22621 tggcgaaatc gttatcgccc cacgtgtact tgaaaaaatc attgctatcg ctactgcaaa
    22681 ggtagagggt gttcactctt tttcaaacag atcagtgtct gatacccttt caaaactttc
    22741 actcggccgt ggcatttatc ttaaaaacgt ggacgaagaa ctcacagcag atatctatct
    22801 ctaccttgag tacggagtaa aagttcctaa ggtagcggtt gctatccaga aagctgtcaa
    22861 agatgccgtc cgtaatatgg ctgatgtaga actcgctgct atcaatattc acgttgcagg
    22921 tatcgtccca gataaaacac caaaaccaga attgaaagat ctatttgacg aggacttcct
    22981 caatgactag tccactatta gaatctagac gccaactccg taaatgcgct tttcaagctc
    23041 tcatgagcct tgagttcggt acggatgtcg aaactgcttg tcgtttcgcc tatactcatg
    23101 atcgtgaaga tacggatgta caacttccag cctttttgat agacctcgtt tctggtgttc
    23161 aagctaaaaa ggaagaacta gataagcaaa tcactcagca tttaaaagca ggttggacca
    23221 ttgaacgctt aacgctcgtg gagagaaacc tccttcgctt gggagtcttt gaaatcactt
    23281 catttgacac tcctcagctg gttgctgtta atgaagctat cgagcttgca aaggacttct
    23341 ccgatcaaaa atctgcccgt tttatcaatg gactgctcag ccagtttgta acagaagaac
    23401 aataaaaaga aaaagtgttt gatagatatc aaacactttt ttctttgcct cccactatct
    23461 aaaaaaatga taatagatat aattgtaaac aaaaatccag ataggttttg catgattgag
    23521 aaagttaaaa aaactatggc agagaatcgt taatctcaga ttgtcggtag aacgataaac
    23581 aagggcaaaa aagaaaccaa tcagactata atataataaa ctaattggat ctctgtgaga
    23641 tagtatcaaa tggctaatcc caaagatgat agcagatagg ataacatcca aatagtactt
    23701 ggactaggga aagaaggtat tcataaaata ccctctatca agagtctcct caaaaacagg
    23761 accgatgatt acaggcagga caaaagataa gatagtcgat aaaaaggttg gttgtccatt
    23821 tgaaaaaagc acggtaaaat actcatcatg aatattccta tgattaatca aatgagcata
    23881 gcgtgcccaa aaattaccga gaatctgata aaccacataa gttgcaaata agtagaagac
    23941 aaatgaccag ttccagctct ttttctcaaa gataaagagc atctttttct tttttaacct
    24001 ccaaattaat agaaggaaac ttcccactaa tcccattgtt aaaataagag aatagacatc
    24061 agctcctaac cctaaaatga tcgtcacata caatccaatt gtttgtggta aataggtaga
    24121 tagtaaaata ataagcaaaa atattccaaa ttgtcttagt ttttttgtgt ttctcatcgt
    24181 acttttttga aagattaccc tgctcggaag ccgtacttcc aagcatctat ataagaatta
    24241 agtgcccctt gcctcatata gggagcaaat tctctataat ataaccatct actatatcca
    24301 tcttcccaaa cagcaagacc acctgaagtt tgctccaagt cctcagttga aagaactgta
    24361 aatgtatttg tacctgtcat tgcaagtacc ttcttaaaat agattgttgt aggctcacat
    24421 ttatagtata tttctttttt tgtctatttt atagcccatc tcctcaactg gcaatttttc
    24481 gacctgaatt acatttttcc ataaaaaatg agacctttct agtctcattt agtcattctt
    24541 agtattttct aaatcgttga tagcgttctt ccagcaactc ttctagcggt ttttgtgaaa
    24601 gtctagccag ctctgtttgg agttcttttt tgacactctt aatcagttct ttactagaaa
    24661 gtcctatttc agaaatcacc ttatctacca cgtccatttc taacagttca tgcgaagtga
    24721 ttttcatcag ttctgctgct tccatagcgc gagtaccgtc cttccataaa atggaagcaa
    24781 agccttctgg actgagaatg gcatagatag aattttccag catccagaca cggtccgcga
    24841 cagctagagc cagagccccg cctgaaccac cttcaccgat aataatggcg ataataggaa
    24901 ctttcaggtc actcatttcc atgagattgc gagcgatagc ttccccttga ccacgttctt
    24961 ccgctccgac accaggataa gcacctgctg tattgataaa ggtcacaact ggacggccaa
    25021 atttctcagc ctgtttcatc aaccgcagtg cctttcggta gccttctgga tgtggttggc
    25081 caaaattccg tttgaggttg tcttgcaaac tcttgccttt ttggatacca accactgtta
    25141 cagcttgatc tccaagccaa ccaataccac caacaactgc accatcatca cgaaaagaac
    25201 ggtcaccatg taattggata aattcatcaa aaatgcctgt cgcaaagtcc aaggttgtca
    25261 agcgactctg ctcacgcgct tctctgacta tttttgcaat attcatctag gactccctcc
    25321 atgcaatctg actaggctag caatcgtatc tggtaagtct cttcttttga caatagcatc
    25381 cacaaagcca tgttctaata ggaattctgc cttttggaaa tcctcaggca agctttcacg
    25441 aaccgtattt tcaatcacac gacgcccagc aaaaccaacc aagctctgtg gttcagccag
    25501 aatgatatcg ccttccatag cgaaagaagc tgtcacacca ccagtcgttg gatctgtcaa
    25561 aatggtcagg taaaagagac caacatttga atggcgttta accgccgcag agatcttagc
    25621 catctgcatg agactcatga ttccttcctg catacgggct ccaccagagg ctgtgaatag
    25681 gacaactggc aatttttcga cagtcgcata ctcaaacaaa cgagtgattt tttcacctac
    25741 aaccgtaccc atagaagcca tgataaagtt agaatccata atcccaagag ccacagtctg
    25801 acctttaata agagcagttc ctgtcacaac ggcttcatgc agacctgttt tttcacgcat
    25861 agatgccagt ttcttttggt aaccagggaa atgcaaggga tccttgcttt caatccctgt
    25921 aaacaattct ttgaaggttc ccatatcaat cgtcaaagcc aagcgttctt gggcagaaat
    25981 acgaaaggta tagctacagt gcggacagat acgttcactt cccagatcct tctgatagat
    26041 ggtatgctta cagcctggac actgggaaaa taattcatct ggaacctctg gcttagcttg
    26101 aggtttttcc ctaaccgaac gattgggatt gattcgaata tacttatctt ttttactaaa
    26161 tagagccatt gattcccctt ttcggtttaa actcttaaag tcattttatt ctttttcttg
    26221 atatttaggt aagaaggttt ccatcaagaa ggaagtatca taatccccag caatgacatt
    26281 gcgatctgaa atgaggtcaa gctggaaatc tgcattggtc tgcactcctt caatctctaa
    26341 ttcatagagg gcacgttgca ttttcatcaa ggcgtcaaaa cgattttcgc cgtgtactat
    26401 gattttggca atcatactat cataataagg cggaatggta taacctggat aaactgctga
    26461 atccacgcgc aaaccaactc caccacttgg cagatagaga ttagtaatct tacctggact
    26521 tggagcaaag ttaaaggctg ggttttctgc attgatacga cactcgatgg catgaccacg
    26581 taggacaata tcttcttgct taacagacaa aggctgacct gccgcaatgc aaatctgttc
    26641 cttaacgata tcaacacctg aaacaaactc tgttactgga tgttctacct gaacacgagt
    26701 attcatctcc atgaaataga aattgctact tgcttcatca agaagaaatt caatggttcc
    26761 tgcattctca tagccaacaa actctgccgc tcgaacagca gcagcaccta tttcatgacg
    26821 cagcgttttt ccgattgcaa tcgagggact ttcttccaaa accttttggt tattcctttg
    26881 aagagaacaa tcccgttcac ccaagtgaat cacatgtcca tgctcatcac ctaggatttg
    26941 aacctcaatg tgccgagctg gatagataac ccgttctatg tacatggcac cattgccata
    27001 attggccttg gcctcactag aggcagtttc aaaggcagaa acgaggtcat ctggtttttc
    27061 aaccttacga atccctttac cacctccacc tgctgaagcc ttgagcataa caggatagcc
    27121 aattttttca gcaacaatca aagcttcttc agagttatgc acttctccat ctgaacctgg
    27181 tataacaggc acacctgctt taatcatctg agcacgcgca ttgatcttat cccccatcat
    27241 atccataaca tgaccagatg gaccgataaa cttgatacct acttcttcac acatggtcgc
    27301 aaatttggaa ttttcactga gaaatccaaa accagggtga atagcttctg cctcagtcaa
    27361 gactgcagct gatagaactg cattaatatt gagataagac tctgttgcct tgccaggacc
    27421 aatacaaact gcttcatctg ccaaaagcgt atgaagagct tccttatcag cagttgaata
    27481 aaccgctacc gtcgcaatcc ccaattcacg tgccgcacgg ataatacgaa ccgcaatttc
    27541 accacgattg gcaattaaaa tttttcgaaa catggagaac ctccttagtt cccaattgca
    27601 aaagtaagga taccactggc tgcaagcttg ccatccactt cagcctttgc ttcaaccaca
    27661 gctatggtgc cacgacgttt tacaaaagtc gctgtcataa ccaattggtc gcctggtaca
    27721 acttgcttct tgaacttaac cttgtccata ccagcgtaaa agaccagttt tcctttattt
    27781 tcaggttttg ataactccaa cacaccagca gtttgcgcca aggcttccat aatcagaaca
    27841 cctggcataa ctgggtattg aggaaagtgg ccgttaaaga aaggttcgtt aatggtcaca
    27901 tttttgatag caacaatggt atcctcgctc acttccaaga cacggtccac tagaagcata
    27961 ggataacggt ggggaagagc ttctttgatt ccttgaatat cgatcatttg atacgtacca
    28021 atcctttacc aaactcaacc atttcttcgt tagagacgag aatttccgtt accacaccat
    28081 ccttaggagc tgggatttca ttcatgactt tcatggcttc gataattacc aatgtttgac
    28141 cttttttgac actatcacca actgtaacga aggcaggttt atctggtcca gcagccaagt
    28201 aaaccactcc aacaagtgga ctctctacaa gatttccctc actagccaca cttgcttcag
    28261 ctggagctgg aacttcttct gctacagtct ctgctggagc agatgtagga gctactggat
    28321 tcggtgttgc tagaacgggt gctggagcga cttgagttgc aacttcaggc acaggtctcg
    28381 cttcattctt gctaaactgc aactcatccg tcccattttt ataagaaaat tctctcaaac
    28441 ttgactggtc aaattgagtc atcaagtctt taatatcgtt taaattcata cttatctatt
    28501 ctcccaacgt ttgaaagcaa gaactgcatt gtggcctcca aaaccaaaag tatttgaaat
    28561 agcgtatgga atttctttct ccaagccttg tccataaacg acattagctt cgatataatc
    28621 tgatacttca cttgtcccag ctgtcattgg tacaaagtta tgacgcatag cttcgatggt
    28681 gacgatagct tctactgcac ccgcagcccc cagcaaatgt cctgtaaaag acttggttga
    28741 tgatacaggt acttccttac caagaacagc tacgatagca ccactttctc ctttttcatt
    28801 ggcaggagtt gacgttccgt gagcattgac ataggctact tgctctggag aaatctcagc
    28861 ttcttccaag gctagtttga tggccttgat agctccctga ccttctggat gtggagaagt
    28921 catgtggtag gcatcacaag tatttccgta accaaccact tcagccagga tagtagctcc
    28981 acgtttttca gcgtgttcaa gactttctag aaccaacatc cctgaacctt cacccataac
    29041 aaacccattg cgatccttat caaatgggat cgaagcacga gttggatcct ctgtagtaga
    29101 gagagctgtt aaggcttgga aaccagcgat ggcaaaaggt gtgatagaag cttctgttcc
    29161 tcccaccaac atcacatctt ggaaaccaaa cttaatggag cggaaggcat ccccaatcgc
    29221 atcatttgat gaagagcagg cagtattgat agatttacaa acaccgtttg caccaaaacg
    29281 catggctaca ttcccagaag ccatatttgg taaagctttt ggaagagtca ttggtttgac
    29341 acgtttgggt cctttttcat gaaggcgaag tacctgatct tcaatttcct tgattccacc
    29401 aataccagat gcaacgataa caccaaaacg atccctatta agagcctcta catcaagatt
    29461 ggcatgattt acagcctctt gggctgcata caaggcatat aaagaatagt tatcaaaacg
    29521 gttggtatct ttttttacaa agtatttatc gaacggaaaa tcttggattt ctgccgcatt
    29581 atgcacatca aagtcactat gatcaaattt tgtaatgcca ccaatgccga ttttcccagt
    29641 tgctaaacta ttccaaaatt cttctggtgt atttccgatt ggagatgtta ctccataacc
    29701 tgttaccact actcgattta gtttcattct tttcacctct agctttcgct acatacttaa
    29761 gccaccatca atggcaacca cttgaccagt tagataatct tggcctgcta aaaatactgt
    29821 caaatctgca acctgctctg cctgcccaaa ttctttcatc ggaatctgag ctagtgtagc
    29881 ttccttaatc ttatctgata agatagctgt catatcagac tcaatcattc ctggagcaat
    29941 cacattgact cgtatattcc gactagcgac ctcgcgtgcc acagacttgg taaagccaat
    30001 caagccagcc ttagaagcag catagttagc ttgaccaata ttccccatca aaccaacaac
    30061 actagacata ttaatgatag caccttctct ggctttcatc atcggtttca agactgattg
    30121 tgtcatatta aaggcaccag tcagattgac cttgagcact ttttcaaaat ctgcttctgt
    30181 catcttgagc ataagagtat cttgggtaat ccctgcattg ttgaccaaaa catctactga
    30241 acccagttct gcaatagctt gatcaatcat acgcttagcg tctgcaaaat ctgatacatc
    30301 tcctgaaatg ggaaccacct tgataccata gtttgaaaac tcagcgagca attcttctga
    30361 gattgcccca cgactgttta agacaatgtt ggctcctgct tgagcaaact tgtgggcgat
    30421 ggcaagacca attccacgac tcgaacctgt aataaagata tttttatgtt ctagtttcat
    30481 ttttttcctt tcaaaacttc tacttatttt agtctatttt tctaaaagtg ctactaaact
    30541 cgcttgatct tccacatgag ctaagtgagc agtttgatca atttttttaa caaaacctga
    30601 caagactttc cccggtccaa tctcgataaa gttgcttatg cctgcttctt gcatgacccc
    30661 aatactttca tagaaacgaa cgggttcctt gacctgacgc gtcaagagct gagcaatgtc
    30721 ctctttttgc atcacagcag cttctgtatt gccgactagg ggacaagtaa aatctgaaaa
    30781 acttacctga gctagagttt cagctagttt ctggctagca ggctcaagga gagcggtgtg
    30841 aaagggacct gacaccttaa gaggaatcaa gcgtttggca cctgcttctt gcaaaagttc
    30901 aaccgctcga tcaactgcaa ccacttctcc agcaatgacg atttgtgcag gtgtgttata
    30961 gttggctgga gtaaccactc caagttcaga agctttttga caggcttctt caatgacctc
    31021 tactggcgta ttgagaactg ctaccatctt gccagagtca gcaggagccg cttcttccat
    31081 ataggctcca cgcttagcta ccaaggcaac cgcatcttca aaatccaagg cgccgcttgc
    31141 caccaaggca gagtattctc caagagacaa accagcaacc atatcaggct gatagccctt
    31201 ttcttgcaat aaacggtaga tagcaaccga agtcgctaga atggctggtt gcgtatagcg
    31261 ggtctgattg agtttgtctt cttccgtatc gatgagataa cgtaaatcat aaccgagcac
    31321 ctgactcgct cgatcaatcg tttctttgac aatcggatac tgatcataga aatcccgtcc
    31381 catccctaga tactgggcac cttgaccagc aaataaaaag gctgttttag tcatttctta
    31441 caactcctgc ccagcgagag gcttcttctt gaattttctt agcggctccg taatacaaat
    31501 cttttaggat ttcttcagct gtttcttctt tagaaacaag ccctgcgatt tgacctgcca
    31561 tgacagagcc accatccaca tcaccgtgaa caactgcttt ggctagggca cctgctccca
    31621 tttgttcaaa gatttctaaa tcaggatctt cctgcttaaa ggcatctttt tcagccagtt
    31681 caaaatctct agtcaactga tttttaatag cacgaacagc atgaccaaag tgctgagctg
    31741 aaatcgtagt atcaatatcc cttgctttta aaattttctc cttgtagttt ggatgggcat
    31801 tcgactcttt tgcaactaca aaccgtgtcc ccacctgtac agcctctgca cctagcataa
    31861 agccagccgc agcaccttca ccatccgcaa ttcctcctgc agcaataaca ggaatagata
    31921 tagctgtggc tacctgtcgc accaaggtca tggttgttaa tttaccgata tgccccccag
    31981 cttccattcc ttctgcaata acagcgtctg caccgatttt ttccatgcgt ttagctaaag
    32041 cgacactagg aacaacagga ataacgatta tcccagcttc atggaaacgt tccatatact
    32101 tgcttggatt tcctgctcct gttgtgacaa ctttaacacc ttcttcaata acgagatcca
    32161 cgatatcttc cacaaaggga gataagagca tgatgttgac cccaaagggt ttatcagtca
    32221 atgatttgat tttatcaata ttggccttga caacttcttt cggggcattt cccccaccga
    32281 taattcctaa tcctccagcc ttggaaacag cccctgccaa atcaccatca gcaacccagg
    32341 ccatccctcc ttggaaaata ggatagtcaa tcttcaataa ttctgtaata cgcgttttca
    32401 tagtgcctcc aaccttcctt gcttacgtaa tagttcgatt tcaccataat ttgacagtca
    32461 aactattacc taaacaagag ggagtgggtt tctccctact ccttctacta atattctgct
    32521 tattttgctt gctcttcaac gtaagcaacc aagtcaccaa ctgttttcaa gtcattttct
    32581 gcttcgattt ggatatcaaa agcatcttcg atttctgaga ttacttggaa caagtccaat
    32641 gaatctgcgt ccaaatcatc aaaagttgat tcaagtgtta cttctgatgc gtcttttcca
    32701 agttcttcaa cgataatttc ttgtactttt tcaaatactg ccatgatagg actcctttaa
    32761 aataaatagt ttttttataa caatgtgttc accacatgat tacctaaatt gtaagaatga
    32821 gcgtgcccca ggtcaagcct ccaccgaagc ctgatagaag aacagtctgg ctaccatcta
    32881 aagggatgag accttgttct acacactctg aaagtaaaat cgggatactg gctgcactgg
    32941 tattgccata ttccatcata ttggctggaa gtttggctcg gtcaacacca atttttctag
    33001 ccatcttatc caaaatacgg tcattggctt gatgaagtag cagataatcc aagtctgtca
    33061 cctctatagg agattcatca atagtctgct tgatagactt ggctacatct cgaatggcaa
    33121 aatcaaagac tgtgcgtcca tccatcttca aaaacgaatc tgcactttct tgatctgaaa
    33181 atggagaatg caaacctgaa tgcccataag ttaaacactc gctgcgactt ccatcgctat
    33241 tgagactctc agctaagaaa tgctcttgct cgctagcttc taacaagaca ccaccagcac
    33301 catctccaaa caacacagct gttgatcgat ccgaccaatc gactgcctta gagagggttt
    33361 cactaccaat caccaagcct ttttgaaagc gaccagaagc gataaacttt tcagcagttg
    33421 aaagagcaaa tacaaatcca ctgcaagccg cggttaagtc aaaagcaaag gctttattag
    33481 cgccaatatt agcttgaaca cgagcagctg tagagggcat catcgaatct ggagtaatgg
    33541 tagctaggat gataaaatcc agttcttttc ctgttattcc agcttttgcc atcagtttct
    33601 tagcaacctc tgtagccaaa tcactggtag attctgttct tgaaatatgc ctttgtcgta
    33661 ttcccgttcg acttgaaatc cactcatcat tggtatccat aatctgagcc aagtcgtgat
    33721 ttgtaaccac ttgctctggc acataatgag caacctgact tatttttgca aaagccatta
    33781 tttcaaatcc tccaaaaatt ggtaaagatt agtcaagcct ttacccatga cagcaatttc
    33841 ttcctcgctc atgccatcaa taattttttc taccatggcc ttgtggaagc gtttatgcag
    33901 tctatgaatc aagcgaccct tctttgtcaa atgcagatgc accacacgac gatcctgttc
    33961 tgaccgaact cgctcaatgt agcccttacg ctctaaattg ttcaaacttg tcgtaacagt
    34021 tccaagagtt accatcaact cttttgacac ttgacttgga gtcacatctg gagccttacc
    34081 gatgacatca atcgtatgca tttctttgat ggagatatcc ttaaaacgac tacctctcaa
    34141 gttcacttcc tcaattacaa ggacattgtt aaatatagat gttaaatatt cattgattcg
    34201 ttggtagtcc atttttcata tccctccttc ttcaaaaaac ttttacaatc aaaacatttg
    34261 acagaaagaa ttatatcaaa attcaaagaa tgatgcaagt attttttatt ttcctgtaaa
    34321 tttaggtctt cttctctccg aatgagctcg cactccttct ttgaaatcct ctgtttgagc
    34381 taaggatttc tgtaggttca gttctaaagt agcgtaaccc tgccagtctt taaactggct
    34441 ctcccaaacc aacttcttaa tggcagcata ggaattactt gaagcacgtc ttaatttttt
    34501 aagaagctgt tctctcgtct tttcaagttt ttcagcttca gaaacgcggt aaaccaaccc
    34561 ccattctagg gctttttctg ccgttaaagc ctctcctgtc atagctaatt gagcagcacg
    34621 cgtcacaccg atactgcggc tcaagagatg aattccccct gcatctggag ccaaaccaac
    34681 accaacaaag gcttggataa acttagcctt atccgtcgcc aaacagaaat ctgccgcaac
    34741 agccatattc gctgcggcac ctgcaacagc accgtcaact tccattaaaa caggtttggc
    34801 tatttgcttg attttataag aaatcgtatt gaccaactct gcgatttttg tcaatgatgg
    34861 aatatcatcc tcatccactg cccgcttcat ctctaccaaa tctcccccaa ctgagaagac
    34921 ctttccattg gcattgatta agataaaatg cacagctgga ttttcttctg ccaaagtcag
    34981 agcttctaaa atctcctcac acatgggaat atgaaaacca tttgcgacct caggacggtt
    35041 caaggtaagg attgccaagt cctcttcaag ctgataaata atgtgttcca tcagggctcc
    35101 tttttatttt ataagcagtt tatactcttc gaaaatctct tcaaaccgcg tcagcttcca
    35161 tctgtaacct caaaacagta ttttgagcag tctgcggcta gcttcctagt ttgctctttg
    35221 attttcattg agtgttaaat tatttcactg tcaaagtata tcttttttag gagcagaaag
    35281 caagaaaaaa tcgactgaaa gtgtctcagc cgataagaaa ggctcgcttt aggctagaaa
    35341 gcatcttatt ttcttcattg aaaaaagcct ttctttctgc tataatcgta taaaatactt
    35401 actttaggag ttcttatgaa agttgttaaa tttggaggta gttctcttgc ctctgctagt
    35461 caattagaaa aagttttaaa catcgtcaaa agcgattcag agcgtcgttt tgtagtcgtt
    35521 tctgcgcctg gtaaacgcaa tgctgaagat actaaggtta cggatgccct gattaaatac
    35581 taccgcgact atgttgcggg taacgatatt agcaagagcc aaagctggat tatcgaccgc
    35641 tatgctgcta tggttagtga attgggacta aaaccagctg tgctagaaaa aatttctaaa
    35701 agcattcacg ccttggccac tcttcctatt gaagaaaatg aatttctcta cgatactttc
    35761 ctagcagccg gtgaaaataa caatgccaaa ttgattgctg cctactttaa ccaaaatggt
    35821 atcgatgcac gctatatgca ccctagagaa gctgggattg tggtcacaag tgaacctggt
    35881 cacgctcgca tcattccatc aagttatgac aagattgaag aattgacaaa caccaatgaa
    35941 gtccttgtca ttcctggttt ctttggtgtc actaaggaaa atcaaatctg tactttctca
    36001 cgtggaggtt ctgatattac aggttctatc attgctgctg gtgtcaaagc tgacctctat
    36061 gaaaacttta cggacgttga tggtatcttt gcagcccacc ctggtattat ccaccaacca
    36121 cactcgattc ctgagttgac ctaccgtgaa atgcgcgagt tggcctatgc aggcttctca
    36181 gtccttcatg acgaggctct tcttcctgcc taccgtggaa aaattcctct ggttatcaag
    36241 aataccaaca accctgacca tccaggtact cgtatcgttc taaaacacag taatgatgaa
    36301 tttccagttg tgggaattgc tggtgactca ggctttgtca gcattaacat gtcgaaatac
    36361 ctcatgaacc gtgaggttgg atttggccgc aaggttctgc aaatcctgga agaacttaac
    36421 atcggttggg aacatatgcc aacaggtatc gacgatcttt ctatcattct ccgttctcgc
    36481 caactaactc ccatcaagga agaagaaatc ctgcgtcagt tggttcaaaa ggctaaagta
    36541 gatcatgcag aaatcgaaca cgacctttct atcattatga ttgttggtga aaaaatgaag
    36601 agccacatcg gagtgactgc tactgcgaca cgcgctctat ctgaaaacaa aatcaacatc
    36661 cagatgatgt ctcaaggttc tagtgaagtt tctattatgt ttgttgtcaa taaagaccaa
    36721 gagaaagcag caattaaagc cctctacaat gccttttttg gagaaagtaa ggaagactaa
    36781 gcatggccca atcacttaac aaaacagtac tcctcagtac gacaggcact tcctacctct
    36841 ctatcgctgg gaaagttggg aaattccttg tcggagatca ggctttggaa ttttacccag
    36901 atgtcaatgt cgaacaattt atccagattc cttggagcca tatcaatcag attggagcca
    36961 atgtcactgg atgcaaaatc agccgccact tcgaagtctt tacagacaaa ggaaaattcc
    37021 tctttgcttc aaaagactca ggtgccattc tcaaaattgc acgcgacaaa ttgggcaatg
    37081 acaaggtcgt caaacttccg accctgattc agacaattag ccaaaaattt aaaaatctat
    37141 ttgcaaaaaa atagaaactt tagtataatc atagcaacgg ataagtaggt tatcttcttc
    37201 tttcagaaag tctgcgggtg ctgcgagcag ataggaggga taggtgaaat tctaccgtta
    37261 gtaacaatta catacacaat caagtgcaca cctgtgaagt tggatggaac cgtggccctg
    37321 ccactccaac gttttgtcag gtgtgctttt ttcataaagg agttcttatg ttagatatca
    37381 aacgtattcg tacagatttt gaagctgtcg cagaaaaatt agctacacgt ggtgtagatg
    37441 ctgctgtctt gaatgaaatg aaagaaatcg atgctaaacg tcgtaacatc ttggtcaagg
    37501 ttgaaactct caaagcagaa cgtaacacag tttctgctga gattgcccaa gctaagcgca
    37561 acaaggaaaa tacagatgac aagattgctg ccatgcaaaa tctatctgct gaggttaaag
    37621 ccttggatgc tgaattggca gaaatcgatg ctaaattgac agaatttaca acgactcttc
    37681 caaatatccc agctgacagc gttcctgttg gggctgacga agacgacaat gtggaagttc
    37741 gccgttgggg tactccacgc gagtttgact tcgaacctaa agctcactgg gatctcggtg
    37801 aagaccttgg tatccttgac tgggaacgcg gtggtaaggt aacaggcgct cgcttcctct
    37861 tctataaagg cctcggtgct cgtttggaac gtgctatcta caactttatg ttggatgaac
    37921 atggaaaaga aggctatact gaagtcatca caccttacat agtcaaccat gattctatgt
    37981 ttggtactgg tcagtatcca aaatttaagg aagatacttt tgaactcagc gataccaact
    38041 ttgtcttgat tccaactgct gaagttcctc tggcaaacta ctaccgtgat gaaatcttag
    38101 acggcaaaga tcttccaatc tacttcactg ctatgagtcc gtcattccgt tctgaggctg
    38161 gttctgccgg tcgtgatacg cgtggcttga tccgtttgca ccaattccac aaggttgaaa
    38221 tggtcaaatt tgccaaacca gaagaatctt acgaagaatt ggaaaaaatg acagccaacg
    38281 ctgaaaacat tcttcaaaaa ctcaaccttc cataccgtgt cgttgctctc tctactggag
    38341 atatgggctt ctcagctgcg aagacttacg acttggaagt gtggattcca gcacaaaaca
    38401 attaccgtga aatctcaagc tgttcaaaca cagaagattt ccaagcccgt cgtgcccaaa
    38461 tccgttaccg tgatgaagca gatggcaagg tgaaactcct tcataccttg aacggttctg
    38521 gacttgcagt tggacgtaca gtggctgcaa ttcttgaaaa ttaccaaaat gaagatggtt
    38581 ctgtgaccat cccagaagca cttcgtccat acatgggtgg agctgaagtc atcaaaccat
    38641 aaaaaataag gtttagctat ttctagctag accttttttc gtaaccaaat cagataagca
    38701 cctagtacaa agaataaaat agttaggcat ataatggttt cagccaatac caggtaatcc
    38761 agaaatggaa gtttcaaaat tccctgagcc atcttgagcg aggtcgctgt gataatggtt
    38821 gggaaggtga gggctgagaa ggctggttga aaaccttgtt ttaaaatgtt gggcagacga
    38881 gttaaaacaa agaaaaagaa ggattgagaa gccaaaatca tgacaatcaa gacccaattc
    38941 ggcaggctgg ttcctcctac tcgaactaga gaagccaaga gtagagagaa aggagcacag
    39001 tagattcctt cttgtccaag caaggctagt gggagtggat gtttctttaa atcgctataa
    39061 ataaggggat agagatagaa ggtcaagaga aaaccaaaac tcaaggtcgc ataggcaatt
    39121 tcgataatac ctaccagagg ataggtcaag gcagccactg ctatccccac atagagaacc
    39181 gtccaacttg gagtggcatg aaccctccgc cctgaacaag caaacttgat ggtaaaacca
    39241 gcaatcaagg tcaaatccaa gagaaatgaa aaccaccaaa tcccttgtgc taccaaagga
    39301 agataagaga atacgcgaaa gacataggtc gataaaatca tcccagccat aggaaaggtt
    39361 gccattcctg acaaaagagg gggcttggtc aattcttgct tggtttcttt ccaattaaag
    39421 agatgcagaa ttagaaagta aatccataaa accaaaccag tcagactaaa aagatgggat
    39481 agaaccggca acgtatctaa aataagattt ccagctcctg ccaaacctag caaacaacct
    39541 gaaaatacta aggggagttt tttcatccta acctccaata atcatgttag tttcagtata
    39601 acataaaagc gcttaaatga tgatttaaaa aaacgaagtc cgattatttc agacttcatt
    39661 ttactcagat atgaattagg cataaggttg caattctgga ttaattggtg tattagctaa
    39721 gttgttggca tagttacaga ggattgctag gctgacacca aaaaccacat ccaaggcatt
    39781 ttgttgagtg tagccagctt ctaaaaactc agacaaggct tcatctccta cacgaccctt
    39841 ggtattgata actgccaagg taaacttagc tagggtatcc aatttaggat ctgtttcaat
    39901 tggagtacga ttgcgaagag cttgaatcaa gtcatcattc atctggattt gtttgatgga
    39961 aaaggctgtg tgacctgcga cacagaaggc acaaccattg gtcacggctg ccgtgatttg
    40021 caccacttca cgctcaacgg gtgtcaggct gttgcgacgg tggatagatg agacaatttg
    40081 gtaggcttct aaaacagtcg gggcattggc caagagaccg attaggttgg gaatatagcc
    40141 attgttgtct ttttctactg tttcaagaat ttctttcact tctgctggtg ctgactctac
    40201 tgtatggata gtaaatgttg tcataagata cctcttttct tattattgac actaatatta
    40261 ttggaaaatc ttataaaatc ctgattccta agtttatcta agataaagct ttattctctc
    40321 ataagatttt cgttgttata ttagtttatc acacttccaa tcacttgcat aatatatatt
    40381 atatatcagg ctgataaaaa ttatttatag gcaaaaaaat cacacgagct gtgtgattcc
    40441 attatttgtc aaaatacttt ttagtttcag caataacgac ttgcgacaag accaagaggg
    40501 caatcaagtt tggcagagcc atcaaggcgt taacgatatc tgcgataatc cagaccatat
    40561 ccaactcgat aaatcctcct aacaagacca tgagcacaaa aaccacacgg tagagccaga
    40621 taaagcgaac cccaaagagg aactcaaaac agcgttctcc gtaatagttc caacctagaa
    40681 tcgttgtaaa ggcaaaaagt acaaggaaga tggtcaagag ggcaggccca aagtgtgaaa
    40741 agactgttga gaaagctgac tgagtcaagg caaccccatt caagtcacca ctccaaactc
    40801 cagttaccaa gatggtcaaa ccagttagag tacaaatgat gagggtatca ataaaggttc
    40861 ctgtcatgga aatcaaacct tgctctactg gttcatttgt cttggcagct gcagctgcaa
    40921 taggagcaga acccagacca gattcgtttg agaacacacc acgcgccaca ccattttgaa
    40981 tagccatccg aacgctagca ccagcaaatc cacctaccgc agcaagggga ctaaaagctg
    41041 aggtaaagac taaagcgatt gtgccaggga tttttccgat attaaagaaa ataactataa
    41101 gagttcctaa gatataaatg atggtcataa aaggaacaac agtagttgaa accttagaaa
    41161 tagacttgag tccaccaaag actgcaatcg ctacaaagac agacaagacg agagctgtga
    41221 tgactggcga aatcgtcgtt gtattttgga tagattctgt aatcgagttg acttgggtga
    41281 aggttccgat tcccaagaga gcaaccaata ctcctgctac tgcaaacaaa acagcaagtg
    41341 gtcgccactt ttctcccatc cctagaagga tatagtgcat gggacctccc gctactgcac
    41401 catggtcgtc cttggtgcgg tatttgatgg ccaagagtcc ttccgcatac ttggtagcca
    41461 ttccaaagaa agccgccatc cacatccaaa atagagctcc tggtccacca accttgatag
    41521 ccgtcgcaac tcctatgata tttcctgttc caacagttga tgccaaggct gtacacagag
    41581 ctgcaaaact ggatacatca ccatgtccct tatcctggat aaaaataagc tgaaaggcct
    41641 tgggcagacg caaaacctgc aagagtccta gccgcatggt taggtaaatc cctgttccga
    41701 ccaataaaat caagaggggc ggtccccaag caaaatcatc gattgattta agcaattcta
    41761 acatttcctt ctcctatcgt ttcaacccca aaagaaagag cacatgcaag atacatgtac
    41821 tctggaatgc ttagataaat gctaaaaagc ggtctatcct agctctgtcc ttttacctga
    41881 gagtttgagc agttgcctgc cttgcccctt cggtgccttt acggtctctc cagagttccg
    41941 tccatttaca gtcatggaaa atcaaacgat tccccacttc tattaaactt cattcggtgt
    42001 tggtatttaa ttgattctaa ttttacaaaa aatgttggct tttgtcaatg tgtttattag
    42061 taaaaattag ttcaacagtt tttactttat aaagtccaga atactgctat cctttaaaag
    42121 tgacaatagt cgcaccactg cctccagcat tttgtggggc atagccgaaa ctcttgacat
    42181 gtttgtttct ttgcaagtat ttggtaactc cttcacggat gactcctgtt ccgataccat
    42241 ggatgatatc aacttgagcc atattgttaa gcaaggcttg gtcgatgaag gtatctagct
    42301 cattcatggc ttcttcatag cgcttgcctc gaagatccag tctagcttga ggtcctcgcc
    42361 cagaagttcg tttcacaaca ttgacctgtt tcttcttgac tggtttttct tgctgggctt
    42421 gaacaagatc aaactctttc tcttccaagg tcatcttaat caagccaact tgggcttccc
    42481 agcggccgtc cttgagttga ctggtcaagg taccacgctg accataactg agaaccacga
    42541 tatcatctcc cacctttgga gctcgttttt tcttggcctt ttgaaggacc ttgtttttag
    42601 acaagtccac tttttcagga gccaattttt tcaacttggc cttggcttca atgatttcgt
    42661 ggggcttgag ttgggattta ctgtggagat ttttgagaat ctggtcactt tcacttaggg
    42721 ccatatccac aatctcagca gcctgttcac gcgccttgtt aagctcggtt tccttttcac
    42781 gattaagctc gttgtagagt ttttttagcg cacggttcat cttgagattt tcttgctcca
    42841 cctcacggat attgtccaaa cgtttgcggc tttccagcgt ctgctcttct aattgctcaa
    42901 tgatacgatt gacgtcattg tcctgatcga tctgctgact ggcatctcct acgataactt
    42961 cagataggcc tagacgtttg gcaatttcaa aggcattact tcggccagga acaccctgca
    43021 taaagcgata ggtcgggcga agagttgcag tatcaaactc catactggca ttttgcacaa
    43081 aggctgtctc aataccgtag gccttgagtt ctggatagtg ggtcgtcgcc atggtcttga
    43141 tttgacgcag gcgaaggtcc tccagaatag ccatggcaag ggctgctccc tcttggggat
    43201 cagtaccagc ccccaactca tccaaaagta agagtgaatg ttggttgacc ttgccaagaa
    43261 tatccacgat attggtcata tggctagaga aggtagacaa gctctgctca atagactgct
    43321 catctccaat atcagcaaag atttcttcaa aaataccaac acgacttccc ttgtctgcta
    43381 aaatcggcaa tcctgactgg gccatgacct gtgtcaagcc cagagttttg agcatgatgg
    43441 tcttcccacc tgtattggga cctgtaatga caatagctgt taaatcttga ccaaaataga
    43501 catcatttgc gacggcattt ttgaccaaag gatggcagac atggagcagt tgaatctctt
    43561 gattttctga cagctgaggc acgactgctt gtctttcttg gataaatcga accttggcac
    43621 gaatcaagtc cagatgaccg ataatccaag cgtcattagc aatctcagcc gcatgagggc
    43681 ggacacgctc agaaatttct tggagaatgc gaagcatttc atagcgctca tctgctcgca
    43741 gactagcaat ttcttcgctc agtttgacta cctcacgtgg ttcgatatag acggtgtttc
    43801 cactagcaga aatatcatga acgacacctg caatcttatt gcggtaggtg tttttgactg
    43861 gtaaaacctg acggccattt ctgctagcaa caattccttc cgtcaacatc tgcgcttttt
    43921 gcttgagtaa gtcttgtaaa acatcgcgca cctgactctc gctatcatgt atttttcgac
    43981 ggattcgcgc caattcttca ctggcaaaat tttcaatgaa acccgcatca ttaaaggcct
    44041 gaagatttcc ttgtaattgc ggaaaatcat gtaatttctc aaaccaaagg gctaattctt
    44101 ccaagctgac attttccaga ttggcgtaaa aattttgaag ttctcggctg gcaagaagca
    44161 cgcgtttcaa gagtaggaac tcctcgatat tgagatccgc tcccatctcc aacctcttgc
    44221 agactcctgc aatttcctta gttgagagaa tagtaaaatg cggttgctcg acgaaaagag
    44281 cctgcatttc tttcatctca gcaaaagcct gtttgatttt atctgctttg gcagtcggag
    44341 ccagctgtct caattgctcc aagccctgct cggtcaacaa atgaggctca aacaaggcct
    44401 tgaccttatc gaactctaat gtttctaata ttttcttatt catctttatt tccttgtctt
    44461 tgaatgtcta ggtgtggtag ctttttacat tctgatagat tcgagtcaaa tctgtaaaca
    44521 aagggctagg aaaactcctg ccctttttat ccgattaaat ttgtcaccca gatttgtttg
    44581 agccaactgg ttgttaccgg tatgctctgg atgatgtgtt ttgcgacgat actcttttca
    44641 agaggatttt gtataactgc catggggatg gtcgccaaga ttgtcaaggc catttgcaag
    44701 acaaataagg tcaccaacat ggacaagata cctgctgaaa cttggaacaa cttaccaccc
    44761 agttttttgc taggaatcaa gtgtaagaga agaccaagta aacgaccaat gctatagaca
    44821 atcccaaata caagcaagta gccgatacct gcataaaaga ccttatccag ctgaaagagt
    44881 tgatccgatg ggaaaaagaa agtcccctga ccttcctgcg aatttgcata agggagcaat
    44941 aaatggaatt gctctccaag ccccttataa aactggccag ccataaaagc cgatgccatg
    45001 gctgaaatca ggtaataaac ctgtaagagc aggcctctcc gatagccgat ataaaatccc
    45061 caaaccaaga ccaatagaag aaggaatgaa atcataagga atcctcaatc ttgctctgtt
    45121 cttgcttaca agtcacaagc ttgtgacgga gttcttctag ctcttgctcc ttatcgtcaa
    45181 attcaatctc acggctgagc tgagttgata aacagttgac tgccaacaaa agagcgattg
    45241 tttcatcatc tgcgctaggc atttgttctt taattgcttg gtatttttct gtcgcaacct
    45301 tagcgatttc ctccataaaa aggttgtcat gttcgcttgt caaggttaac gattttttcc
    45361 cgaatgtaaa tttgaatcga tttagatttg ccataaaatt cacctcacga tattatacca
    45421 aaattcgcta attttgtcag tttttacaaa ttttactgct tttgtggtac aatagaaact
    45481 atggcaagta tcacactcac accaagcgaa aaggatattc aggcttttct tgaacactat
    45541 caaaccagtc tggctcctag caagaatccc tatatccgct actttttgaa actacctcaa
    45601 gcaacggttt ctatctatac ttctggaaaa atcttgcttc agggtgaagg ggctgaaaaa
    45661 tacgccagtt tctttggcta tcaagctgta gagcaaacca gcggacaaaa tcttccttta
    45721 attgggacag atgaggtggg aaatggttcc tactttggtg ggcttgcagt tgtggctgcc
    45781 tttgtcacac ctgaccagca cgacttttta cgaaaactcg gtgtggggga ttctaagact
    45841 ctgaccgacc aaaagatccg tcagattgct cctattctca aggaaaaaat tcagcaccag
    45901 gcactccttc tctcacccag caagtacaac gaggtcatcg gagaccgcta caacgctgtt
    45961 tcggttaagg ttgccctcca taatcaggct atctatctcc tccttcaaaa aggtgttcag
    46021 cctgagaaaa ttgtgattga tgcctttacc agtgctaaaa attatgacaa gtacttggca
    46081 caagaggcca atcgtttcag caattctatc agcttagaag aaaaggctga gggcaaatac
    46141 ttggctgtcg cagtttcttc tgtcattgcg cgtgatctct ttctggaaaa tcttgaaaat
    46201 ttgggacgag aactgggtta tcagcttcca agtggagctg gaacggcttc tgacaaggtg
    46261 gctagccaga ttttgcaagc ctatggtatg cagggactca acttctgcgc taagctacac
    46321 tttaaaaata ctgaaaaagc gaaaaacgct tagaaaggta agttatgaat ttatttaaaa
    46381 atttcttaaa agagtgggga ttattcctcc tgattctgtc attactagct ttgagccgta
    46441 tctttttttg gagcaatgtt cgcgtagaag gacattccat ggatccgacc ctagcggatg
    46501 gtgaaattct cttcgttgta aaacaccttc ctattgaccg ttttgatatc gtggtggccc
    46561 atgaggaaga tgggaataag gacatcgtca agcgcgtgat tggaatgcct ggcgacacca
    46621 ttcgttacga aaatgataaa ctctacatca atgacaaaga aacggacgag ccttatctag
    46681 cagactatat caaacgcttc aaggatgaca aactccaaag cacttactca ggcaagggct
    46741 ttgaaggaaa taaaggaact ttctttagaa gtatcgctca aaaagctcaa gccttcacag
    46801 ttgatgtcaa ctacaacacc aactttagct ttactgttcc agaaggagaa taccttctcc
    46861 tcggagatga ccgcttggtt tcgagcgaca gccgccacgt aggtaccttc aaagcaaaag
    46921 atatcacagg ggaagctaaa ttccgcttat ggccaatcac ccgtatcgga acattttaag
    46981 aaacctaaga ggccgagaat caccaatctc agcctcttct tctatcgtga gaaaatgatt
    47041 ggtaactatc taaacttacc agaacagaaa cacctcaact ctcacctatt catgcaaagg
    47101 aattttatgg aagtttattt ttcaggaacc attgaacgga ttatttttga aaatcccagc
    47161 aatttttatc gcatcctcct cctagaaatc gacgatacgg acgcagagga ttttgatgat
    47221 tttgaaatca ttgtcacagg aaccatggct gatgtaattg agggcgaaga ctatactttt
    47281 tgggggcaaa ttgtccagca ctccaagtat ggagaacaac tgcaaatcag tcgttatgat
    47341 cgcgcaaaac caactagtaa gggcttggtc aagtactttt caagtagcca tttcaagggg
    47401 attggtctca agacagctca gaaaatcgtg gatacctatg gcgaaaatac cattgacgaa
    47461 attttgcaac acccagaaaa gttagaaggc atcgcaggat tctctgccaa aaatcgcgag
    47521 gctttcgtct ccactctccg tctcaactac ggaacggaga tggttttgtc caaactagcc
    47581 aactacggca ttcccaacaa actagccttt cagattcaag acttttacaa ggaagaaacc
    47641 cttgatgtgg ttgaaaatta tccctaccag ctggttgagg atatcaaggg tttgggcttt
    47701 acaattgctg accaactagc tgaggaacta ggcatcgaaa gtcaggctcc tgaacgcttc
    47761 cgcgccggtc tagttcacag tctttttcag gcctgtatgg aaacagggga cacctatgtt
    47821 gaagcacggg atttgctgga acaaaccctt actctccttg agtcttcccg tcccgtggaa
    47881 ctagacccca gccaagttgc ccaagagctc tcctacctga tcgaagaaga caaggttcag
    47941 cagattgata ccaagatctt tgacaacagc ctctttttcg ctgaggaagg tatccgcagt
    48001 cacttgattc gtatccttga aaaaggaaaa cagaagagcc aagatttaga aactattcaa
    48061 aagcatatca ctactgtcga gcaagagctg ggaattgagt atgataacat tcaaaaacag
    48121 gctatctgtg atgctatcca gaataaggtc tttatcctga caggtggacc tggtactggt
    48181 aagacaactg ttatcaatgg gatcatcgct gtttacgccc tgttagaggg acttgacctc
    48241 aggaagaaaa gcaatctgcc cattcttctt gctgctccaa ctggacgagc cgctcgccgc
    48301 atgaatgaat tgacaggttt gcctagcgcg accatacacc gccacttggg aatgacaggt
    48361 gacgatgata ccagtcatct ggaagattac ctagatgctg actttatcat cgtggatgaa
    48421 ttctctatgg tagatacttg gctggccaat caactcttct ccaatatctc ttctaacagt
    48481 aagatcctca tcgtaggtga cagtgatcag ctaccttctg tcagtcctgg acaggttcta
    48541 gcggatctgc ttcatattcc tttgattcct cagactcgct tggaaaaaat ttatcgacaa
    48601 agcaaagaat caaccatcgt caccctagct agtcagattc gacagggcat cttgccagct
    48661 gatttcaccc aaaaaaaagc tgaccgttcc tactttgaaa ttgctagtgg ccatattcct
    48721 gccaccattg aaaaaatctt aggtgtcgcc ctcagaaatg gtattcctgc ccgtgatatc
    48781 caagttctgg ctcctatgta ccgagggacg gcagggattg atgctatcaa tcagctcatg
    48841 caagacctgc tcaatccccc acaaaaagat caactcagtt ttgaagctcc tcagtgccac
    48901 tatcgtaaga gagacaaggt cattcatttg gttaacgatg ctgaaatcaa tgtctttaat
    48961 ggggatttag gagctatcac agacctgatt cctggtaaat acaccgaatc gaaacaagac
    49021 gagattgtca ttgattttga tggtaatgaa gtctcttacc cccgtaacga atggtacaag
    49081 attcgcttgg cctatgccat gagtattcat aagtctcagg gaagtgagtt cccagttgtc
    49141 atcctaccga ttactagtgc tagccgacgt atgctggagc gaaatctcat ctacacagcc
    49201 attacacgtg ccaaaagcaa actcatctta ctaggcgaat tacaagcctt cgactatgct
    49261 acccaacaca tcggaactgc ccgaaaaacc tatctgattg aacgcttcag tgatctactg
    49321 gagaatgttg aagaaaagca acaagctgtc tctgaaacag tcacatcaag tgcctctgaa
    49381 caatcctaca tcctaaccga agaaaactgg gaccgcatcc cagccatgat tgggattaca
    49441 gacacagacc tcaaagagat ttttggaaaa tagtgcatca gaaaacccac caattcaggt
    49501 gggttttctg tttattaaga ttattttact gttgctgtgc ttgtgatcaa ttcaacagct
    49561 tttttgatag tgatatcatg tttcaacatg tcagctgaaa gcaagttttg aacttgtgca
    49621 acttccatgt tgtagtctgc tgccaattgc tcaacttctt tttggatttc ttcttctgaa
    49681 gcatcaaatc cttcagcttt ggcaactgct tcgataacaa ggttagtctt agtacgtgac
    49741 tcagcttctg cttggtattg gttgtgaagg tcttcttgag tagttccagt gatttggaag
    49801 tacatgtcag ggttgatccc ttgacgttgc aaattcccaa ggaattcatt tactgaacgg
    49861 tgaacttctt catggatcat ttcttctgga agttctacga tttcagcatt ttctacagct
    49921 gtatcaattg ctgcaccttc aactgcatct ttgtaagctt cttctttagc agcagccaat
    49981 tctttgcggt atttttcttt caagtcagca agtgtttcaa cttcttcatc aatgtctttt
    50041 gcaagttcat cgtcaagagc tggaacttct ttagctttta cttcgtggat agttgtcacg
    50101 aatttagctt ctttacctgc aaggtcttct gcttggtagt cttctgggaa tgttacgata
    50161 acatcaacgg tttcgccagc tgagtgacct accaattggt cttcgaaacc agggatgaat
    50221 tgacctgaac caagtccaag tgagaagttt tcaccttttc cgccgtcaaa ttcaacaccg
    50281 tcgatagaac caacgaagtc gatcacaaca gtgtcgccgt tttcagcagc agcttccttg
    50341 ataaccaatt cagccaggtt gttgcgttcg cgttcgatac gctcttcaac atcagcgtca
    50401 gttacttctt tttctacatc aactgatact tcaaggtttt tgtagtcacc caattttact
    50461 tcaggttttg taacgacttc agcagcgata acccagtctt gacctttttc cattgaagtt
    50521 acgtcaattt ttggttgggc aaccacttca agaccagctt cttttacagc tgcttcataa
    50581 gcgtttggca aaagagcgtt cataacgtct tggtaaagtg attcttcacc aaatttttta
    50641 tcgaagatag gacgtggaag gtgaccttta cggaaacctg gaacattaag agatttcttc
    50701 actgacttga agacacggtc caattctggt ttgatttggt cttgagagat agtgaaagtc
    50761 aagacaccac ggtttgtttc tttgttttca aatgatacag acattctgtc atttctcctt
    50821 aaaatttttt aaatacagtc tattataaca ttttctataa ataaaatcta gactaatgca
    50881 gccaattata gacaacaagc ctttttccta actaaaacac tcataaagta tagacaattt
    50941 tagactactt tggatatctt ttggttagtc attttccaaa actaatttat ctaatttttc
    51001 agttatattt gacttcatct tctcagtaac atgagtataa acacttaaaa tctttgtttc
    51061 attagtataa tctacacgat ccattatcgc tgttataggt acttccaatt cagcaagcaa
    51121 acttatatgc gaatatctaa aaacatgagc agtcaataca aaatcatctt tcttaatttc
    51181 acttttccta aaactgtttt tcaaaaagta attgaaacaa gttatcatta agggagaacc
    51241 attatttgta aatatataat caccttcttc taaaagaaga tattctttta aaatttctaa
    51301 cactctatca ctaataccaa ttactctata tgaagctaaa cttttcggac tatccaaaaa
    51361 tacttcgtta ttggacgatt acattatagt aaaacgaaat aagaacagga caaatcgatc
    51421 aggacagtca aatcaatttc taacaatgtt ttagaagtag aggtgtacta ttatagtttc
    51481 aatctactat acaagacgaa attgaagaaa tctttccatt ataaaacgca tattatcaag
    51541 gtttttaaac acctaataat atgcgttttt tcctatttta aagactttta tccacctatt
    51601 atacaaagtt aagtatccat cacagtttac aattagcctt cattacctaa cccattcacc
    51661 atccttcaag agagtaacct ttaagaaccg aataaataaa tggcaaattt cgttcattta
    51721 atttaactgc actgttaatt tgattagctc catctcctaa agtatgcact cctactacac
    51781 ggtgactagc atcataaact gtagatccac tagacccctc taaagtatca acttggtaat
    51841 ccaagaacat gccatcatca cttaaaactt gttttttatc tgtatacatt tgatgaattt
    51901 taaaattata tgatagatag cctgtgatag tcacagttat tcctgtcaaa tttttttgac
    51961 tagtaggaag acccaaagtc cctaattttg caccaatggg ctcttctaga attaataaag
    52021 ccaagtcata ttcccttgca tccttagaat ttaaatttct aaattccttc aaataacgaa
    52081 cttcctttac tttgatcttt ccaaatagtt cttgacttgg actaacagcc ggaagaacat
    52141 aaatatcatc cgcttctttc ccatagtcat gtctgtagta gttgtgagcc gctgtaatta
    52201 acacattatc tttaataaaa ttcgcacttc ccctcccttc tacattcatt ccatcggcta
    52261 ctccataata cttagataaa accatagctg aagtcgaata cggatactgt aaagtattat
    52321 caattttaat caaatcatca ttaccgataa tacttctgat tgcttttggt agtatgaacc
    52381 atacgttggt gaaatctcag ataatgaaga atcattagac tctggacctt tttctagtgt
    52441 ctcacttacc tcatattctt cacctgtact agaaataaca ctcaaagcag atactgtcga
    52501 taactggcta gccaataaag tactcgcaat aattgaaata cccaattttt tataaacagt
    52561 tttcttcatt attgtatcct cctaatgtaa ttatagcgta ctattctaaa tttcttaatc
    52621 tactatagaa tcaagaaatc taccaccttc tttaaatacc ctccattatc acataaacag
    52681 gtaaactttt caattaatga ctgcgctttt caatcacgct agaggtactt gcttgcttct
    52741 ttgatactaa gttcagccat tctttccttg tttttctcaa taaagcatgt tacccaagtg
    52801 ggattcgttt tggagtagtc tcgcagagtc cagccaatgg ctttattgat aaaaaattct
    52861 gtttggttca agttatgaag tagaatcttt tccattaatt gagtattggt cttctctttt
    52921 cttaacaact ggtggtcaat agcgacacgt ctcagccaga tattatctga taggctccat
    52981 tttatactca atgaaaatca aagagcaaac taggaagcta gccgcagatt gctcaaaaca
    53041 ctgttttggg gttgcagata gagctgacgt ggtttgaaga gattttcgaa gagtattaag
    53101 attatttctt ctagttcaga gtgttcatac accaaactcc ctactactcg atctaggata
    53161 tctaccgtgt cccaccagga ttttgtcacg actaactgct ctagcttagg caaatcggtt
    53221 tcctttagat aagactgcat tgctttcaaa tagttagcag ccacatattg gtattctcta
    53281 ggatcctttt cccagcaagt gtctgcaaaa tcccaatcga taatctttgt ttttttcgct
    53341 tctggaaaat atttttatag agtttatttc tttcaggcac cgcaatacct agaaaagaaa
    53401 attgatggcg catataggct tccatggacc ttgctttttt agagtctttt gctgcttcta
    53461 gctcctcaag taaatctgct aaactcatct aaaactcctc ttgccccacc aaatggtgct
    53521 gaaaggcata gacagccgcc tgggtacgat cgctgacttc aagtttggca agaatattgg
    53581 acacgtgggt cttgaccgtc ttgagagaga taaagaggtc atctgcgatg cgctgatttt
    53641 cgtagccctt ggcgatgagt tggagaacat ctcgctcacg cgcagtcaat tcttcatgaa
    53701 gttccatatg attgcggtgg tattcaacct tcttgctaac ctcttgctca atggccagct
    53761 cgccagcagc taccttactg acggcatgaa gcaattcatc tgcactagaa gtcttgagca
    53821 tatagccttt ggcaccagca tctaagactg gcatgatttt ttcattgtcc aaataagagg
    53881 tcacaatcaa aatcttggct tcaggccatt ctttaaggat tgctaaggtc gcgtcaatcc
    53941 cattcatctc aggcatgaca atatccatga caatgacatc tggacgcagt tccaaggcca
    54001 agtcaatccc ttgagacccg ttggacgcct cacccacaac ttctacatcg tcttggaggt
    54061 caaagtagct tttcaagccc aatcggacca tttcatggtc atctactagt aaaattttca
    54121 tctttactcc tttatcattc cttatctaac aggggaatac ggatatcaac cgccagccct
    54181 tgcttgggag ctgtcaagag ttgaactgtt ccagccatat cttcaacccg ctccttgata
    54241 tttcgcagtc cataactcaa gtcgtctaag ctccctaact ggaaaccaat cccattgtcc
    54301 accaccttca gttgcaattc aacatctgtc tgatagaggt agacatctag gcaagatgcc
    54361 tgggcatggc ggagggtatt gctaatcaac tcttgcagga tacggaagat atgctcctcg
    54421 attttcttag gcaatttcgt catattctgc ttgagactaa ccctaagatc actcttgtcc
    54481 tcaagctctt ttaagagaat ttgaatccct tctatcaagc tcttctgctc cagttcaact
    54541 ggtcgcaaat gcaagagcaa aacccgcaaa tccttctggg cagtttctaa aatagctgtg
    54601 acactctgca actggatctg catcttttct ctatccaatt tcaaagcctg ctgactgata
    54661 cccgataaaa tcatgtgggc cgcaaacaac tcctgactga ctgtatcgtg caaatcccga
    54721 gcaattcgct tccgttcctt ctcgatgatt tcctcttcct gagcaaggct atgattttca
    54781 gctttttgaa gagcttctgt caaaaggtta agtttacctg ataaggactt gaaactggca
    54841 tccaaatctg gatctgcaac ctgaaccact tcttgccctg ccaataaacg cttgagatta
    54901 gcctgcattt ttcttagaga aagctcttcg atccctcgcc aaaacagggc taagagacag
    54961 gttatggaca tgctgaaaac caacaataaa aagacaaatt tttctgtttt ttcgacatcg
    55021 tgcaaaaaga tagaccagtc aaaatcaagt atttccagca agctgtggga gaaaaaaaag
    55081 acaaacagga aggaggtgag agcaataatg acataggctt gttttttcat cctctaacca
    55141 cctccacatc accaatcata gtggtcaaga aaatcttgac actcttgtta ctcttgagat
    55201 agtcttttgt ttcttgatga tagtgttcat tgcggagggc tcgcttgggc tggttgaaaa
    55261 aagtcaaatc cccatagaga cagttaacgc tgagactgac ttccacatct acaggtacga
    55321 tgattttggt cgttcctacc atctttctga ggataatgac attgtcatga ttggttaaga
    55381 tgaccctctc cagatgaata gtgtccttgc ccatgaagcg aaagagattg atatcatcga
    55441 attggcaagt ctggtagctt gaaaaatgat gaagatttcc aaaccaacga tttttctcct
    55501 tcttaaccgt cacgacctct tcaaaaacca aattggtctg ctctttttcc tggttcatca
    55561 tcgggtaaag aagaaagagg ctatagataa ccgcaacaaa aatagctaga atcacaaaag
    55621 gattgagcat aacgatgaaa aagaagagaa tggttgccgc tactaaaaga agattatttc
    55681 cctctttacc agtgtagtag cgaatcaaaa gcaaaaagag gaatagtatc agcagaaaac
    55741 gcgaaaaatg ctctgatacc atcaaaatca gagctcctgt cagaagacag gcttcgataa
    55801 ataaaaagat tttaaatttt ctcataggtt catcctctcc cttctatttt atcacaattc
    55861 aaaaaagtca cctcagtctg aggatggaaa aaaggcgctg gttacgcctt tttcatctga
    55921 tcctttgctt cttttaattt tccataaaga agatagtcta ctttttgtag atctgctatg
    55981 gtggcacagt taagggaaca cataatcaag cgtaggtctg ctttccagcc ttggacaatg
    56041 ccaatcactt cttcaactgt gtaggtttca accaattcca gaacggttcg tgacaatccc
    56101 acagacttag caccaaaaac caagcactta atcatatcca gcggattccg aacccctcca
    56161 ctaaccaaga gttcgacctt atctttccat tcttgggcat tgagaagggc ctgcatggta
    56221 gactgacccc attgattgag gtaatcacgc tggccactac gacggttttc gatataggca
    56281 aagctggtgc caccacgacc cgataggtcc actgtacgaa caccgaattc ataggctctt
    56341 tcgattgtct tggcatccat tccaaagccc acttccttga ggacaatagg aacgggaatt
    56401 tgctcgctat aatctgctag atgcgattgc cagcttctaa acttcctttc tccctcgggc
    56461 atgagtaatt cctgcatgac attgacatgc acttgcaata gaacaggatt catctcttct
    56521 acagtctgaa gccctaactc gacaggcttg tccaatccaa tattggttcc aaggaggaga
    56581 ttgggatgac tagacttgac agaaaaagaa tcatccgttg gatttttgag ggctgcgcta
    56641 taagaacccg ttacaaataa aataccacag gattccgcca cctgagccag cttttgattg
    56701 atttctcttc ccttattact tccaccagtc atggcattga tataaaaagg aaagtcccac
    56761 tttcgaccag caaactctgt cgaaagatcg atttcatcca gattgtaaag aggcaaggaa
    56821 gaatgaatca gctccacctc atcaaagcta ttataggaac ttttctgctc aagggcatag
    56881 aggatatgct cgtccttacg atttgtcgtc atgtcctatc ctttcttgat ataagagctc
    56941 aatccccaga tcggcccaac gattttttaa ggtttcggtt gattgcgcat caaaactcaa
    57001 ggcgatgcca cagtcaccac caccagcacc actactcttg gcaacggcct gcaaatcttg
    57061 actggcttct ttcaactgtc taagcaaagg cgtgtaaata tctgtactca agccttctaa
    57121 aagcttgctg gctacttcta cttgctcgat aactttttcg gctttcccct gctccaaggc
    57181 ttcgaccaaa gaaaccaccg tttcttttga ggaacttaaa aaattttgat tgatattttg
    57241 cttgatttgc tggaccatgt gactcgatac agccacttcc ttggtccatc ccactaagaa
    57301 atcacattct aaagttggtt tcacttgtga gataaaaaat ccccaatcac gctccagaac
    57361 tgtcgccaag ttttcttctt ctaaccaagc agccaccttc tggcgatcaa atgactggta
    57421 gagaaccaaa tcctctgcca caatacaggc aaggtcgccc atggaaccat tgtctcctcg
    57481 cttgagcaag acagcgctag tcagcttgaa caagagattc tgatcaaccg aaagattata
    57541 gagagccagt aaagccttga caaccaagac aacgacgctg ccactagaac ctagaccaaa
    57601 ctttttccct tctcgttcca ttttgccaca gatttttagg gaaaaaggtc ttaaattctg
    57661 accgcgaaca gcgaggaagt ctcccatcaa agcaatcgtt tcttgaatca agctgtagtc
    57721 aggattaggc cttaagtcca ctgcgaaatc aaacatatct gaatagatac ggtagctgtc
    57781 agaaaaagca atttcagccc tcatatagat gggaatatcc tttatcaaag ctaactgccc
    57841 tggctctaaa atagcatatt cacctgccca atagagtttt ccgcaagttt taacagcaat
    57901 catcttgact caaatccttt gtttttgaca caatcaagcg ataacgctga ccgaaaattt
    57961 ctgataaatg ctccaagtct ttctcctgac agaagacctt aacattggga ccagcatcca
    58021 tggtaaagta gcaggcctct cctttctcac gaagctggcg aacaaagtcc atagcctcat
    58081 aagaggcatc cgtcagataa gaaaaggctg gactagcagt ctttgtcgta gcatgcatag
    58141 ccagggcatt tttctccgtt aattctccaa tcttggcaaa atcattttcc ttgagataaa
    58201 tcagcatatc ctgatagtcc ttctcagact gacgaaccca gtcgtcgaaa gtcgtcgagg
    58261 tttccacaca aagtttcatc ccgtcacggc tagagattgg ttttttcttg tcctctagca
    58321 ccaacataat catagctagt ttcaagtctg tctctacagg gtaaatttct ccactatcct
    58381 tatcccaggc tcctagtggt ccataaaaac tccgagaaga agagcctgag gcaaacttgg
    58441 cttcctgcgc taactgactt ctatccaatc caagcttgaa ataagcatta caagccttga
    58501 ccagggcgga caaaccacta gaacttgagg acaggcccgc tgccgtaggc atattgtttt
    58561 gagtatcgat acggacaaag ccctcaccag ctggacgata acggtcaata atcttactca
    58621 tcttggcatg ctcgacctca ttttgtagct gaccattgat gtaaaattcg tcagctgtta
    58681 cattggctgg taaaggcgac aaggtcgtct ctgtatacat attttccaaa gttagagaaa
    58741 tactgctagt agcaggcacc atctcttttt cttttttctt tccccaatat ttgataatag
    58801 caatatttgc gtaggaacgt actgttacag gctctctatc catgtctgaa cagctccttt
    58861 ctcttctaat ctttctgcta gttcttgtgc gtgtgtcaaa ttggttacca aggctatgat
    58921 acaacctcct agcccaccac cgctcatctt ggcacccaga gcaccatggc taagagtcgt
    58981 ttcaaccaaa aagtctgcct cagggctact gactccaatt tcttttaaat gtaaatgcgc
    59041 ttgactgagg atttgtccca gtccttcagc atctttttgt gaaatcgcaa cttctgcttg
    59101 ctgggttaat tctcccaagg catgcaaaaa cggtagggca tccttgccct tattttgaac
    59161 cacttggatg gcttcacgag tatgaccata aacacccgta tcggcaatca ccaaataggc
    59221 ggataaatcc atctcaagtt ctgtaaatcc tacgttcttg ataaagcgaa taggttggtc
    59281 actgagacag gtcttagcat ccaaaccact aggattcata tgggcaatca tttcagctcg
    59341 attgaccaag atttctagta catcatgagg cagatcagcc tgatagtagt caaataccgc
    59401 acgaatggcc gctatgctga tagccgctga cgaacccatc ccccgtttct cagggatagc
    59461 cgagtcaatc tcacaacgaa tgcaggcttc tgtgatatcc aaatactcca gtgaggcata
    59521 aaccgccatg gacaaggtat cctcctcata aaggcgccaa ggactctctg caggaactac
    59581 cttacaggtc acctccacct ccaaaagagg cagggaaatg gcaggataac cgtaaacgac
    59641 cgcatgttcc cctattaaaa ttatcttact atgtgcctga ccgacaccaa ctttttttgt
    59701 cattttttcc ttttactaga cgaaaaaacg tcttattttt catacaagta ttaattcttt
    59761 cctatctatt ttattatatt ttcacaaaaa aagcgattgt ttccattcac aatcgcttct
    59821 ttcattaccg aacccattca ccattataat tgacagaata gccatctaca atcgtattca
    59881 ctgccaaggc acctgagcta taagcgtagt accatctgcc attgacctgg aaccaacctg
    59941 tcgtcataga acgatgaaag aaactccata ccattaagta aagaggaaag tcatgaggga
    60001 gcatgcgtca ttgacaacct attttagtga cgtacaaagt ttcattaaca agtactcgtt
    60061 tcggccattt ataggtgcgg tgtttgcaga aatagggttc aatcttcgcc cattcttgat
    60121 cgtttaaatc agtatcatat gctttgcgtg tcataactct agtttaacat ttttttgtga
    60181 atacaggttc taaataatcg accacgaaaa tttcttaagt ggaaaacgcc ttatgaagta
    60241 tgctacggga aacttatgca cttaatttga caactcaata tgtaaaaata tatactata
//
LOCUS       DAVBNZ010000006        59157 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000006 DAVBNZ010000000
VERSION     DAVBNZ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59157
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.006"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            1..200
                     /locus_tag="VQ860_000345"
                     /pseudo
     CDS             1..200
                     /locus_tag="VQ860_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(317..664)
                     /locus_tag="VQ860_000346"
     CDS             complement(317..664)
                     /locus_tag="VQ860_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3118842.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(775..2550)
                     /gene="spxB"
                     /locus_tag="VQ860_000347"
     CDS             complement(775..2550)
                     /gene="spxB"
                     /locus_tag="VQ860_000347"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET3118843.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2757..5000)
                     /locus_tag="VQ860_000348"
     CDS             complement(2757..5000)
                     /locus_tag="VQ860_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3118844.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSHAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLVISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5010..5381)
                     /locus_tag="VQ860_000349"
     CDS             complement(5010..5381)
                     /locus_tag="VQ860_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET3118845.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5392..5787)
                     /locus_tag="VQ860_000350"
     CDS             complement(5392..5787)
                     /locus_tag="VQ860_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET3118846.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5971..6069
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6153..6944
                     /gene="thiD"
                     /locus_tag="VQ860_000351"
     CDS             6153..6944
                     /gene="thiD"
                     /locus_tag="VQ860_000351"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3118847.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7153..7785)
                     /locus_tag="VQ860_000352"
     CDS             complement(7153..7785)
                     /locus_tag="VQ860_000352"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3118848.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7778..8581)
                     /locus_tag="VQ860_000353"
     CDS             complement(7778..8581)
                     /locus_tag="VQ860_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3118849.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8581..9105)
                     /gene="thiW"
                     /locus_tag="VQ860_000354"
     CDS             complement(8581..9105)
                     /gene="thiW"
                     /locus_tag="VQ860_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET3118850.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9110..9802)
                     /gene="tenA"
                     /locus_tag="VQ860_000355"
     CDS             complement(9110..9802)
                     /gene="tenA"
                     /locus_tag="VQ860_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET3118851.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9813..10463)
                     /locus_tag="VQ860_000356"
     CDS             complement(9813..10463)
                     /locus_tag="VQ860_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET3118852.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10465..11850)
                     /locus_tag="VQ860_000357"
     CDS             complement(10465..11850)
                     /locus_tag="VQ860_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118853.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREINQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11851..12411)
                     /locus_tag="VQ860_000358"
     CDS             complement(11851..12411)
                     /locus_tag="VQ860_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3118854.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12673..12761)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12970..13599)
                     /locus_tag="VQ860_000359"
     CDS             complement(12970..13599)
                     /locus_tag="VQ860_000359"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3118855.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13601..14383)
                     /gene="thiM"
                     /locus_tag="VQ860_000360"
     CDS             complement(13601..14383)
                     /gene="thiM"
                     /locus_tag="VQ860_000360"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3118856.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            complement(14794..15333)
                     /locus_tag="VQ860_000361"
     CDS             complement(14794..15333)
                     /locus_tag="VQ860_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET3118857.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENNYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAE"
     regulatory      complement(15548..15636)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15890..17026)
                     /gene="lctO"
                     /locus_tag="VQ860_000362"
     CDS             complement(15890..17026)
                     /gene="lctO"
                     /locus_tag="VQ860_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET3118858.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17651..19141)
                     /gene="lysS"
                     /locus_tag="VQ860_000363"
     CDS             complement(17651..19141)
                     /gene="lysS"
                     /locus_tag="VQ860_000363"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET3118859.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLKEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19269..19415)
                     /locus_tag="VQ860_000364"
     CDS             complement(19269..19415)
                     /locus_tag="VQ860_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET3118860.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            19642..20310
                     /locus_tag="VQ860_000365"
     CDS             19642..20310
                     /locus_tag="VQ860_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3118861.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRIPV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPLIGIVLSSEVCATLGLVFLGSSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVVLPSFSANVIFLIKKTSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTCHAGFGNPST
                     LSRK"
     gene            20270..20650
                     /locus_tag="VQ860_000366"
     CDS             20270..20650
                     /locus_tag="VQ860_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HET3118862.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            20660..20947
                     /locus_tag="VQ860_000367"
     CDS             20660..20947
                     /locus_tag="VQ860_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3118863.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            20948..21716
                     /locus_tag="VQ860_000368"
                     /pseudo
     CDS             20948..21716
                     /locus_tag="VQ860_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21728..22594
                     /locus_tag="VQ860_000369"
     CDS             21728..22594
                     /locus_tag="VQ860_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3118864.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHLTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(22681..23328)
                     /locus_tag="VQ860_000370"
     CDS             complement(22681..23328)
                     /locus_tag="VQ860_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118865.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23325..24023)
                     /locus_tag="VQ860_000371"
     CDS             complement(23325..24023)
                     /locus_tag="VQ860_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118866.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYVLG
                     ANEQMNFSCVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(24033..24785)
                     /locus_tag="VQ860_000372"
     CDS             complement(24033..24785)
                     /locus_tag="VQ860_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118867.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24785..25549)
                     /locus_tag="VQ860_000373"
     CDS             complement(24785..25549)
                     /locus_tag="VQ860_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118868.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25645..26048)
                     /locus_tag="VQ860_000374"
                     /pseudo
     CDS             complement(25645..26048)
                     /locus_tag="VQ860_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26228..26860)
                     /locus_tag="VQ860_000375"
     CDS             complement(26228..26860)
                     /locus_tag="VQ860_000375"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET3118869.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26894..27595)
                     /gene="pyrF"
                     /locus_tag="VQ860_000376"
     CDS             complement(26894..27595)
                     /gene="pyrF"
                     /locus_tag="VQ860_000376"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET3118870.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(27828..29027)
                     /gene="divIB"
                     /locus_tag="VQ860_000377"
     CDS             complement(27828..29027)
                     /gene="divIB"
                     /locus_tag="VQ860_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET3118871.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(29037..30095)
                     /locus_tag="VQ860_000378"
     CDS             complement(29037..30095)
                     /locus_tag="VQ860_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET3118872.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(30097..31449)
                     /locus_tag="VQ860_000379"
     CDS             complement(30097..31449)
                     /locus_tag="VQ860_000379"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET3118873.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(31553..32194)
                     /locus_tag="VQ860_000380"
     CDS             complement(31553..32194)
                     /locus_tag="VQ860_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118874.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32196..34216)
                     /locus_tag="VQ860_000381"
                     /pseudo
     CDS             complement(32196..34216)
                     /locus_tag="VQ860_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(34287..34586)
                     /locus_tag="VQ860_000382"
     CDS             complement(34287..34586)
                     /locus_tag="VQ860_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3118875.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(34952..35206)
                     /locus_tag="VQ860_000383"
     CDS             complement(34952..35206)
                     /locus_tag="VQ860_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET3118876.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(35226..37067)
                     /gene="typA"
                     /locus_tag="VQ860_000384"
     CDS             complement(35226..37067)
                     /gene="typA"
                     /locus_tag="VQ860_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET3118877.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            37229..37954
                     /locus_tag="VQ860_000385"
     CDS             37229..37954
                     /locus_tag="VQ860_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3118878.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTNLKRIQFGDFTLNPDLA
                     EGNYHPLNQKELQIIKNYLEMSR"
     gene            complement(37994..38221)
                     /locus_tag="VQ860_000386"
     CDS             complement(37994..38221)
                     /locus_tag="VQ860_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118879.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(38310..38690)
                     /locus_tag="VQ860_000387"
     CDS             complement(38310..38690)
                     /locus_tag="VQ860_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3118880.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(38690..38959)
                     /locus_tag="VQ860_000388"
     CDS             complement(38690..38959)
                     /locus_tag="VQ860_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET3118881.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            39023..39931
                     /locus_tag="VQ860_000389"
     CDS             39023..39931
                     /locus_tag="VQ860_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3118882.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(39985..40740)
                     /locus_tag="VQ860_000390"
     CDS             complement(39985..40740)
                     /locus_tag="VQ860_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3118883.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(40761..41690)
                     /locus_tag="VQ860_000391"
     CDS             complement(40761..41690)
                     /locus_tag="VQ860_000391"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET3118884.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(41705..42328)
                     /locus_tag="VQ860_000392"
     CDS             complement(41705..42328)
                     /locus_tag="VQ860_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET3118885.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(42321..43559)
                     /gene="hflX"
                     /locus_tag="VQ860_000393"
     CDS             complement(42321..43559)
                     /gene="hflX"
                     /locus_tag="VQ860_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET3118886.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(43552..44436)
                     /gene="miaA"
                     /locus_tag="VQ860_000394"
     CDS             complement(43552..44436)
                     /gene="miaA"
                     /locus_tag="VQ860_000394"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET3118887.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            44557..44727
                     /locus_tag="VQ860_000395"
     CDS             44557..44727
                     /locus_tag="VQ860_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET3118888.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(44775..45614)
                     /locus_tag="VQ860_000396"
     CDS             complement(44775..45614)
                     /locus_tag="VQ860_000396"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET3118889.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(45711..46670)
                     /locus_tag="VQ860_000397"
     CDS             complement(45711..46670)
                     /locus_tag="VQ860_000397"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET3118890.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(46797..47794)
                     /locus_tag="VQ860_000398"
                     /pseudo
     CDS             complement(46797..47794)
                     /locus_tag="VQ860_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(47844..48461)
                     /locus_tag="VQ860_000399"
     CDS             complement(47844..48461)
                     /locus_tag="VQ860_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3118891.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(48462..50183)
                     /gene="pabB"
                     /locus_tag="VQ860_000400"
     CDS             complement(48462..50183)
                     /gene="pabB"
                     /locus_tag="VQ860_000400"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET3118892.1"
                     /translation="MHRKTVIDFRILGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGKLLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(50244..55886)
                     /locus_tag="VQ860_000401"
     CDS             complement(50244..55886)
                     /locus_tag="VQ860_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3118893.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQFPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEKGHVGEALAQEQLPEYKVTEGTLVETSTTDLDYKTET
                     TEDPTKYTDEETVLRTGEKGSQVTKTTYKTVEGVKTDQVLSTSTEVTKEPVNQQVIRG
                     TKPIEGTLIEESLEKIPFKEVVKEDDQLKKGLEVVAQEGKEGQKKITKTFNTIKGVKT
                     EDAPKVTEEILEEPQDKILKRGTKSFEKPVLTITEIESKDLKRTSDVKYSLENPSKAA
                     IKSITLTLKKGDEIVKTLNVSPEDLTTTLTDLQYYKDYKLETKMVYDRGEGDEEEVLK
                     EEPLRIDLKKVEIKDIIRTDLIKYENQVETDETRLTSVPTDLSNYYLKVTSNDHKTNL
                     LAVQKIEESTIDGKQVYKVIAVADNLVQRNVDNRFEETYTYYIEKPKASQAGIFYDFE
                     ELIQAIQTNPAGEFKLGQSMSARNVVPKGKSYITSEFTGKLLSDGDKRYAIHNLEHPL
                     FDKIKAGTVKNINFENIDIDLSNQDNIAAIANEISGTTRIENIKAIGTITARNNVAGF
                     VNNIKEDATLENVAFIGSINSAGNNSTVGGIAGSNYMGFVNRAYVDATITANNANASM
                     LVPFVQYKAHSWLSGTKGKLTNSVAKGILDVKNTKYVGGITSKTWPYGAVQDNVTYAK
                     VIKGQEIFGSNDVNDGDANPFVSNLFGVIGYSSSEDGTGKDNKNKNKLKHLSKSEADA
                     KVASFNITAAKFVSEPYELNKLNNVSSREAAYESIQDYNADYKLAYKNIEKLQPFYNK
                     DFIVNQANKLDKNNKLNTKEILSVTPMNNNNFVTDLGDANKIIVHYADGTKDYFNLSS
                     SDEGLSNVREYTITDLGIKYTPNIVQKDHSALINGIVNILSPIELQSNPIYQKLGRTG
                     SNRVNAIKDLYLEESFDHVKANLNILVTKLVENEDHQLNNSSAAQQMILDKVEKNKAA
                     LLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGKNVSVLDRLIEIGSREDNIKGHRTY
                     DAFSEIISKTTLSENLVNFLNYNRRLFTADVNIYDWFKKATEGNVYIAERASEVDEIK
                     AAKYKVWDNLQSATHRKMILPLLNLNKSHVYLISNYSAMAVGTAEKLGHSSFDGIKNQ
                     IEKAADSYRNYFDFWYRLSLDKVKNMLVKNTVTPLWEGYQAPGGWPDKYGKRNNKEDY
                     APLRELFGPIGKYYGNNGTGAYAVIWDNPLDTRTEVNYIALSMIDEFGISVYTHETTH
                     VNDRAIYLGGYGRRSGTHAEAYAQGMLQTPVPSTWFDEYGALGINMTFYRPNDGNQWY
                     ITDPKTLKTREDIDNYMKGYIDTLSLLDYVEGDAVISKHDDKLNQLWFKKVDPIERTV
                     GSKDQYDKVRNMSSDDWKGITLNSVNDLVDNNLMTNRMMNNNIYKPEVFDPGIAYVGI
                     KMMNSIYAGNTSEGAPGAVTFKNNAFRLWGYYGYDKGFLGYASDKLKSQANKEGKQFG
                     DQYIIQKISDGRFQSFADFKKEYYKELLEKANAGFTPFTIDGETIHNYDELKSLFAKA
                     LEEDMVTNKVNGKLVQVKEKVYKKLLQQTNSFKTSIFK"
     gene            complement(55908..56471)
                     /locus_tag="VQ860_000402"
     CDS             complement(55908..56471)
                     /locus_tag="VQ860_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET3118894.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(56587..58278)
                     /locus_tag="VQ860_000403"
     CDS             complement(56587..58278)
                     /locus_tag="VQ860_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3118895.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(58275..59012)
                     /locus_tag="VQ860_000404"
     CDS             complement(58275..59012)
                     /locus_tag="VQ860_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3118896.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        17517 a        12989 c        10677 g        17974 t
ORIGIN      
        1 attcctccat acacaccaga gatgaaccca ttgaacaagt gttgaaagag attcgtaaac
       61 gtggatttaa gaataaagcc tttcgaactt tggaagatgt catgaatcaa cttcaagatg
      121 tcatacaagg actggagaag gaggtgataa agtccatcgt taatcggaga tggactagaa
      181 tgctttttga aagcagatga gtattatatg caatttcttt atataaaaag accggattgc
      241 tccgatcttt caatagttca tattctcaat ttctatttta aaaatagcta aggttaacgt
      301 caaatgacta cgcgacctat ttcatacgat aaaaatcaag cactagacca gcaggtcctt
      361 gaactaataa ggactctgtt ccccaatcgg ttacagttgg tccgtgtaaa acctttatac
      421 caagctcgtt caaccgtttg tagttctggt ctacatcctc aacctcgata tgaataatga
      481 ttcctgactg aaagttttcc aaaggaacca aatgattttg tgacaacata aggcagtgac
      541 taccaatcgt aaactgagca aaaccatcat cagcataatc tgccttttta tccaagatat
      601 gctccaagtc agcacagact tggggaacat ttgaaacgat aatatctaat tgatttaaat
      661 tcatttactc tcctccataa aaagaccgga ttgctccgat cttttaaagt tctgctctat
      721 gaaaatcaaa gaataaagtc tacaagtttc atatttgatt ttcggcgaga ggaattattt
      781 aattgcgcgt gattgcaatc cttcttcttc caagaagaga cggaatggta cgagttcttc
      841 tgcttcgtat ttttccttga aggctttgat agcttcttct gagtgaagtt ttggatccaa
      901 ttcaagtact tctactggaa gtggacggtg ttgagtgatg cgagcatcga tgacaacagt
      961 tttaccttct ttgttcaatt taacagcttc tgcaacaact gcatcgatgt cttcgatacg
     1021 gtcaactgtg aatccaacag ctccttgagc ttccgcaatt ttagcgtagt cagcgtttgt
     1081 gaagtctaca ccaaacaagt gtttgtttgt atcttcgtat ttgttcttga tgaagccgta
     1141 ctcagcattt gagaagacaa ggttgataac tggaaggtcg tattgaacgt ttgtgataac
     1201 gtctgggtag cacatgttga atgctccgtc acccatgatg ttccatactt ggcgatctgg
     1261 attgtctttc ttagcagcga taccaccagg aagggcaata cccattgtcg caaagagtgg
     1321 agatgtacgc cacatgttct taggtgtcat gtgaaggtga cgagtagatg tttgagtagt
     1381 gttacctacg tcgattgagt agatagcgtc ttgatcagca tgtttgttga ttgcattgta
     1441 aacttgatac aattgcaatt caccctcagt tttaccttcg agtttgttca tgtaatcacg
     1501 ccagttttga ttgttcttaa cgtttgcacg ccaccatgga gttgattcaa ctgggtttac
     1561 tttgtcaagg atagctttag ctgcttgacc agcatcacca aggattgaag cgtcaagggc
     1621 atgacgttta ccaagtttgt aagggtcgat atcgacttgg atgaattttt cagtgttctt
     1681 gaatgcttcg taaacttcag cgaatgggaa gtttgaacca aggaaaagaa ctgtgtctgc
     1741 ttcaaagacc acttcgttgg ctggtttcca accaacacgg taagcagaac ctgtcaaacc
     1801 ttcatagttc cattcgaaag cttcaaagtt tttaccagtt gtgatgattg gtgctttgat
     1861 tttacgtgac aattcagtaa tcacttcacc agctttaaca ccaccaaatc cagcatagat
     1921 aactgggcgt tcagcattgt tcaagatttc aacagctttg tcgatttcaa cttcgttcaa
     1981 agcaggagcg atgaatgagc gttcgtatga acctgaaccg tagtatgagt tttcatcgat
     2041 ttcttggaaa ccgaagttta ctggaatttc aacaacagct ggaccttttt tagaaactgc
     2101 agcacggcag gcttcgtcaa ttacttttgg caattgctca gcgtaagcta cacgtttgtt
     2161 gtaaacagcg ataccgttgt acattgggtt ttggttaagc tcttggaaag catccatgtt
     2221 caattcgtta actggacgtg atccaaggat cgctaggaat ggagtgttat ccatagctgc
     2281 atcgtaaaca ccgttaatca agtgagtcgc acctggacca cctgaaccaa ctgcaacccc
     2341 gattgagccg ccgaatttag cttgcataac cgctgcaaga gcacctgtct cttcgtggcg
     2401 aacttgtaag aaacggatat ctttgtcttc agccaaagca tccatcaatg agctgagtgt
     2461 tcctgatggg ataccgtaga ttgtatctac gccccatgtt ttcaatacgt taagcattgc
     2521 tgcagatgca gtaattttcc cttgagtcat aatgataact ctccttcaat ttttttaaac
     2581 ttggagaaaa cgattacata gaattggaaa cgttctccaa atttttacta ttccactgta
     2641 tcatatttat gctgactttt ctaaaaatct gctcaaaact ctctattctc tattctaata
     2701 cagttttgaa agtgttgtca tttctgtttt ataacaaaga aatctagtca ttacttttag
     2761 tctattttac taaaatttaa cagaagggaa ctggtcagaa cagatacaga actaaaggcc
     2821 atggctagac ctgccaattc tgggttgaga gccagtccaa cacctgaaaa gactcctgct
     2881 gcaatcggaa ttccgacaac attgtagata aaagcccaga aaagattgag tagaattcga
     2941 tgaaaggttt tcttactcat atcaaaggca cgaaccactc ctaaaagatt attggttgtc
     3001 aacaccaaat ctgctgactc gatggcgata tctgttccag ctcccatagc aatccccaca
     3061 tctgctacac taagggcagg agcgtcattg ataccgtccc caacaaaggc tactttccct
     3121 gactgttgca gtttatggat ttcatgggct ttttcttctg gcaagacgcc tgcaatgacc
     3181 tcttcaattc cgatttgatc tgcaatagca cgcgccacac cagcattgtc tcctgtcagc
     3241 atgactgttc ggagaccacg tttttttagc tgactgatga ctagcttagc attttcctta
     3301 ggaatatctt gcaaagcaag caagcctttg atttcattgt caacagctaa gaacacaact
     3361 gtcttagctt ctttttctag ttcttctagt ttatcttgat aagtattaga aatatccatg
     3421 ccatccagca ttttagcatt tccaagtaaa acttgttttc cattgattcg ccctgaaaca
     3481 cctttcccgt gcaaggcctg aaaattttca acagtttgaa actcaagtcc agcttcactc
     3541 gctcgcttaa cgatagcctc agccagtggg tgttgagaag catcttccaa ggaggctgcc
     3601 aatccaaaca cttctacttc gtcgccgatg atatctgtta ccacaggttt cccttccgtc
     3661 aaagtcccgg tcttatcaaa gacaagagtt tgaactttct ggatttcctg taagacagtt
     3721 ccatttttga ggagaacccc catcttggca ctacgtcctg tccccaccat aagggctgtc
     3781 ggtgttgcaa gtcccaaggc acaaggacag gcgataatca aaaccgccac tccgtagaga
     3841 agagaggaca caaagctagc tccaagcacg accacactat ccctgagcaa gacgaaccaa
     3901 acccaaaagg tcatgattcc taaaatgaca actactggga caaaaatccc tgaaatctta
     3961 tccgtcaagt cctgaatcgg cgcatgactt gtctgagctt tcttcacaaa atccacaatc
     4021 tgagccaaaa cagtctctga gccaactttt tctgctctaa agacaagcgt tccactatga
     4081 ttgatggttg agccaatgac agtatctcca actgtcttgt ccacaggcag actctcacct
     4141 gtcaccatgg attcgtcaat actagagaca ccttctacta cgacaccatc aacagcaatc
     4201 ttttcaccgg gacgcactcg aatcaggtcg cctaccttga cttgttccaa aggaacttgg
     4261 acataactat catcactcaa gacttctgcg gttttagctt gcaagtccag taatttctcc
     4321 acagcttggg acgtattttt tctcattttt tcctcaaaaa ctgctcccaa aagaacgaaa
     4381 aagaggataa atccagcact ttcgaagtaa acagggagac cagcaaagag agcaactagg
     4441 ctatagaaat aagccactag agttcccagc gcaaccaagg tatccatgtt ggcattgtgc
     4501 tttttaaaac tggcccaagc actctggata tatggcttac ctgcaactaa cataataggc
     4561 gttgttgcta gaaaggttcc ccaatgcatg acttgatgac taatgctacc tgtcaacatc
     4621 ccaatcatga gaatcacaag aggcacagta aagatactag taatccaaaa acgttgcagg
     4681 agagatagag attttcgagt cttctcaacg actatatagc ttcccttttg catcttcatg
     4741 ccacaagaaa attcatgtcg ccctaattct tgaggtgtaa aacgaatgac tttctcctca
     4801 tctacgccga ttggttccaa gataccttct tcttcaaaca gaatttcctt ataacagttt
     4861 gaaggagtag cacgatgaaa ggtaatctca gctggaattc ccttttgaag ctggatatgg
     4921 gctggatgat agcctttttc agctcggata cggatttttt gaatgccatt ttctaagctt
     4981 gctttcacaa tttctgtcat agtctccacc tactctacaa tcatcttgcc gtgcatcatg
     5041 ttcataccac aagcaaagcc aaactctcca acctgctcag gcgtgatttc cactacatac
     5101 tcttccccca ttggcaggtt cgcatgtaca ccaaaatctg gaaaaacaat ttgatccaga
     5161 catggtgaag gatccttgcg gtcaaagaca atgcgtgctg gcactgattt cttgaggaca
     5221 atcaactcag gagtatagcc tcccatgact tccactcgaa tctcttggta tccgtttttt
     5281 tgctgggctt tttgtccaga tttttcaggc tttttgaaaa accaaaacaa gataaacgcg
     5341 ataagggcaa tacaaataat ggttacaata ctatttaaca tggcgtctcc tttacataca
     5401 attacatctt acttctgtta cagcacttga tttcttctct gaaatcacag cttccaagtc
     5461 ttccaagtca gtctgagtaa attcacattc tacaatcaag tcagccaaca aattcctaat
     5521 cctacgggaa caaaccttgt ctttgatatc ttggacaagt aaatcccgac tttggtctag
     5581 agttaaaagc gctgaataaa caaaggactt gccttctttt ttccgagtca gacactcttt
     5641 ctcaaccaaa cgagccaaaa gagtttgaat ggtcgacttg gaccagtcga accgctctgc
     5701 caaaacccta atcaaatctg tactggtctg ctccccctgc atccaaataa tcttcatgac
     5761 ctgccattct gcatctgaaa tctgcattac catacctcca aaatctacat ttgtcaatta
     5821 cactcatcag tatactctta aaatctacat ttgtcaatta tagaaataat attttcttcg
     5881 aaaaatagaa ttttaatcat ttgaaaaacg atttgcagtc aaatattact atataaacaa
     5941 taaaaatatg ctatactaaa gaaaaaagaa aacaaccact aggggtgcgt aaagctgaga
     6001 ttaacgactg ttagatccct ctgactcaat ctaggtaatg ctagctgatg gaagtggaaa
     6061 tgataatggg gactagcagt cttctattgc ctttctaaaa cagactagct tgttcttaag
     6121 aatacaaact tcagttggtt gggaggtttt agatgactta tttacccgtt gctttgacca
     6181 ttgcagggac tgaccctagt ggtggtgctg gcattatggc agatttaaag tcattccaag
     6241 cgagagatgt ctatggaatg gctgttgtaa ccagtcttgt cgctcaaaat accagaggtg
     6301 ttcagctaat cgagcacgtt tctcctcaaa tgttgaaagc ccaattggag agtgtctttt
     6361 ctgatattcc acctcaggct gtaaaaactg gaatgttggc tactactgaa atcatggaaa
     6421 tcatccaacc ctatcttaaa aaactggatt gtccctatgt ccttgatcct gttatggttg
     6481 ctacaagtgg agatgccttg attgactcaa gtgctagaga ctatctcaaa acaaacttac
     6541 tacctctagc aactattatt acgccaaatc ttcctgaagc agaagagatt gttggttttt
     6601 caatccatga ccccgaaggc atgcagcgtg ctggtcgcct gattttaaaa gaatttggtc
     6661 ctcagtctgt ggttatcaaa ggcggacatc tcaaaggtgg tgctaaagat ttcctcttta
     6721 ccaagaatga acaatttgtc tgggaaagcc cacgaattca aacctgtcac acccatggta
     6781 ctggatgtac ctttgctgca gtgattactg ctgaactagc caagggcaag agtctttacc
     6841 aggcagttga taaggccaag gcctttatca caaaagctat tcaagatgcc cctcaactcg
     6901 gtcatggttc tggtccagtc aaccatacaa cttttaaaga ttaagaaaaa aactctctag
     6961 ttcccacttt aagggaatta gagagttttt atactcttcg aaaatctctt caaactacgt
     7021 cagcttccat ctgcaacctc aaaacactgt tttgagctga cttcgtcagt cttatctaaa
     7081 acctcaaggc agtactttga gcaacctgcg actagctttc tagtttactc tttgattttc
     7141 attgagtatt aattaggaaa gaatgtcatg caactttgtt aaaaaggctt gcgtttttgc
     7201 ctcaatatct tctgcttgca tcaaatcacg tacaacagct acaccagcta tgccagtgcc
     7261 cataagctga tcaatattct ccgaagtcaa gcctccaata gcaactactg gaatggcaac
     7321 cgtttggcaa attgttttca aggtcgatat cagagtaatg ggcgcatttt ccttggtggt
     7381 ggttgggaaa atggctcctg tacccaagta atctgcacct gatttctccg cttccagagc
     7441 tcttttaacc gttttagcgg tgacaccgag gattttttca ggacccaaga ctttgcgagc
     7501 taccgaaact ggtaattcat catctccgat atgcagacct gctgcatcaa ccgcaagaca
     7561 aacatccaac cgatcatcga ttatcaaggg gacctgatag gcatctgtta tttccttgac
     7621 ttgttttgcc agttgataat attgattggt tgtgagattt ttttctcgca attggactat
     7681 ggtaacccct gaacggcagg ccgtctcaac ttttgcaaga aagctttcca cggaatcttg
     7741 atagcgattg gttaccagat atagtctaag tgcttctcta ttcataaacc tctcctttga
     7801 tggtatctag ccaattttca tctcttctta ggagcgaaag ctgattgagt acttggtaac
     7861 gaaattcttc caatcccatt ccttgaacaa ctattttctc agcagcgata ttgagataag
     7921 agactgctaa gcaagaagct tcaaaaccag tctttccttg gctgagaaaa acggctgtta
     7981 aggctccaac caagtctcct gtccctgtta tccagtctaa ttcagtacag ccattctcca
     8041 gtacagcaac ttgattctcc gaaacaataa ggtccttggg gccagtaact aagaaagaca
     8101 taccaggata ggtctgacac cagtctttca agacttgaag caaatcctcc gtttcttgat
     8161 ctttagcact cgcatcgacc ccaacgccgt ggtgctttaa tccaacaaga cttcgaattt
     8221 ctgacatgtt tcctttaagg accgtaggtc tatagtctaa aaggtcttta actaagctct
     8281 tacgaatgga tgaagtcgtt acgccaaccg catctactac catcgggaga gaagattggt
     8341 ttgcatacga agctgccatg cggattgctt tttccttctc agctgacaaa tgccccaaat
     8401 tgatgaagag agcctgactt tgcttagtaa aatcaagaac ttcacgggga tcatctgcca
     8461 tgacaggttt gcatcccaga gccaaaatcc catttgccag catctcacaa gaaatctcat
     8521 tggtcataca gtgaatgagg gaactagagc ctataggaaa aggatttgtc aatgcctgca
     8581 tcattctatc ctttcagcaa agaaatatcc ttgcactttt ttaaagaatt cctgcttgat
     8641 taaaaatcta aatgcaataa aggaaatcgc tgtaccaatc aaggttgctc cgaaaaatcg
     8701 aggagtgtag ataaaccaac taagcttagc agccgatcct gtaaagagca ccataacagg
     8761 ataggaaaca atagaaccaa taatacctgt tcccacaatt tctcccaagg cagaaaagta
     8821 aaattttcga ccgtacttat aaaagagacc tgctagaagg gctccaaaag tcgctcctgt
     8881 gagagctaaa ggcggaatcc cttgagtcgt catacggata aaggctgtca ctgtagccat
     8941 agccaaggca taaacaggtc ccatcatgat tcccgctaga atattgacta cactggacat
     9001 cggtgccatt ccctcaatcc gaaagatagg tgtaaggact acatcaaggg caatcatcat
     9061 agataaaatg gtcaatttgt gaacttgtag ttggtgcttt ctcatgtttc tattcttctc
     9121 ctttttctaa agactgtaaa tcgctcttcc atgtctggtg ttggtaagcc atctcccaaa
     9181 acttagcttc catatgaaca ctgatgtgga aggcatctag cattttttgc ttatctgtct
     9241 catcactttc tcgataaagc tgattgacca gtgctccctc ctctctgatc tgttgctcta
     9301 actcatccgt aatataagtt tcaatccatt gttgatagag aggatttggt gatggtttaa
     9361 gattaagtga tttgcctata tcatggtata accaaggaca aggaagcaag cttgcaaaag
     9421 ctatggctaa gttcggttct gcaaattgcc tataaatatg agaaatgtaa tgataacagg
     9481 ttggagcgat tggatgttgc tccatttcct ggtcgttgat ttccaattcc ttgaaaaatt
     9541 gttggcgaat aaataactca ccctccacta aaccctgagc attttgtttc aagagtcttt
     9601 tcatctcttg gtttgaagtc ttatcagcca aaagatgata gatttctgag aaagccttca
     9661 gatagtaggc atcctgaatc aggtaatagc ggaaaatggc aggttctaaa ttcccctctt
     9721 gtaattgtaa aataaaggga tgatgaaagg aagcctgcca agctttcttg gataattcca
     9781 tcgcaatatc tgtaaattcc ataataactc ctttataaaa atagactggt ttgaagcaat
     9841 aaaaagaaaa gcaggtagat taattttgtt tttttaggaa tataaaaagt ccgatagcta
     9901 ttcttcaact gtgcatgttc gtcatatccg tgagcagata gagctctcag gtaaagatgg
     9961 cgccacctaa agactgtcat cagaacctta ctgtaaatca agggcgacca aaaatgtagt
    10021 ttttgaccac gtaataggca agcttctttg agggacttga tttcttgctg aatgagagga
    10081 aaagaattga ataccacaat caaggcatag gaccaagagc gtgatagccc cttttgagcc
    10141 aagtacaaga gaagctcttt tagtgaaata gaggaaacaa agacaaggcc gatacaaact
    10201 gtcacaaagg ccctcgttcc aagcatgact gcctgtgaag catctccgtg taactgaact
    10261 gcccagtagt tggcaaaaga tggtaaaatg gcaagtatga tcatccaagc taacatttta
    10321 aatcgacggt aatagagcat aaagagaata caaaatgcga ctaccgaaag attcagagca
    10381 atcgaaggaa tgaaagatgt ttccaaggat aaaatcagca agaagagact gataatcggt
    10441 gtctgggttg ctactttgac catactatct cacctcccct tgggtattgc tactctgaga
    10501 tgtaagtggt ttggtaatgg tcacttcttt cacatgccga agaccctgac tagtcatctc
    10561 aatccaataa tcaaccacag aaatcaaagg gtctaaacga tgactaatga gcagaaaact
    10621 tcttccttga ttcctctcct ccacaatcca cttgcaaaaa taatggcagg ctctatcatc
    10681 caaacctgca aaaggttcat ctagcaagat cacggaagcc ttactggtca agatggtcag
    10741 gagctgaaga attttttgct gaccaccact taattgatag ggactcttat cgactgcctg
    10801 ctccaaatca aaatatcgta aagcttgaaa aatccgctga tttctttcag aatcaggtcc
    10861 atctaattga agctcctctc gcagactgac tcggataaac tgcttctcag cttcctgaac
    10921 aacacccgtc agatcacggt acaaactctt tttctttttc aggactgtcc ccttccatgc
    10981 aatgcgcccc ttatactttt gaaattgaag aatagaccga aagagggttg atttcccgac
    11041 accattgtca cccaggatac aggaaatccc ttgatagaat gtgaaatcag caattgaaaa
    11101 gagggggcga ttaccaagct caccagtcac acggttcata tggaataatt ccgggctaga
    11161 agcaacttcc tttgaagcaa cctgtgtcat ctcataggaa gggatttgat ttatttccct
    11221 tagttttccg tctcttagct caaccatatg gtcgatatag gctttatagt cagataaatc
    11281 atggtcgcac aaaataactg tcttcccatc aagagccaac tcttttagaa tctccaatat
    11341 ctcgattctg ctcttgcggt caatggaagc gaagggctca tccaagagat ataccctagg
    11401 attcatggca aagaggacag ccagcgctgc tttttgcttt tccccacctg ataggtgatg
    11461 aatgggacgg tgtaagattg cctcgcaacg acattgctgg acaacctctg ctattttaga
    11521 atcaatttcc tgaaggtgat agccgatatt ctccaaggtg aaaatcaact cctcaaacaa
    11581 gttctccatg gtaaattgat gattgggatt ttgcaagaga atgccaacct tctggacacg
    11641 tgcgatgata gaaagctgac tgacctcgct cccatctatc aggacttgac cactataggg
    11701 aagagaactg acttgggcaa tcatttgaaa gaggctggat tttcctgaac cactgctccc
    11761 aactaacaag gtaaaggctt gcgcatgaaa agtaaaatca aacggctcag agaagattgg
    11821 ggactgaatc gctcgtagtt ccagacccat ctatgctttt cctccagttg caaactgatg
    11881 atagagtttg acaatggcac gaaccaagat ggtacagaag aaataaacag aaataaaacg
    11941 taccacaagc aaggaaagga caaacggaag ggaaaaggcg tagtaaccta acttaatgta
    12001 ttcatagaca aagctaacaa gcgtaatccc aatactatta gcagttagag agagccaact
    12061 ttcatagcga ttcttagtta cgataaaacc aaattcactt cccaaacctt gaaccaagcc
    12121 agacaaaaga gctcctagac caaattggct accataaagg acttcagcaa gcgcagctag
    12181 cacttctcca atcgttgcac ttccgactct cggaacaaag atggcagcaa tgggcgcagc
    12241 catacaccag agaccgaaga ggatttcatt ggcaaaggcc tgcaaaccaa gaggtgttaa
    12301 gagtagactg agaatattat acacatatcc tgaaccaacg aaaaccccac caaaaaagat
    12361 agacaagaaa gcaagcaaga taacatcttt taactgccat tttttcaaca taaaaaactc
    12421 ctttttttaa agaaaagtgg ggcactcaag aagaccgacc taaatacttt gtatagcaga
    12481 ctgaatttag aacagtacac aagaacacta aaatatttct agaaattaat ttgaattttc
    12541 taattgattt gttcgcatct tatttcaatc tactatatca tcttcatcca gtttcgtaaa
    12601 agaaaaaact ctaattacag atacgaatta gagttcagct tacaagatta gacagttctt
    12661 ttcgacatac gaaaaaaaca tttcacattt cccttcgcca gtcttaactg tatcaggttc
    12721 aatgggtatc atctcagcct aaagcacccc aaatgccttt attatttaat tatgtgatta
    12781 ttataacaca cattttatac tagttcaaga aattgaactg gaaatacagc cttgcactca
    12841 caaagacagc agatctttct tttgcaaaaa acaaatgacc tgtttgatga attagctatt
    12901 caagctgaat ctagacatag ctttttaaaa aaggaaaatc ctacttactt agaatccaag
    12961 gatagatatc tattgttcac tcatttcccg aacagttttt tctatatttt ttgcatacga
    13021 tattgccgaa atgattgaaa cgccgtcaac attggtcttt ataatgtctt taatatgttt
    13081 cgtctgtatc ccaccaattg caactaaagg catttgtggc aatagttttc tcatcaattc
    13141 aagaccttca taacctatag caccaccagc atcatccttt gactgggtat caaatacagg
    13201 accaacacca acataatcta catattcaac ttttgattgt tgaaattctt cctcgttttt
    13261 tatagaaaga ccaattattt tatctggcat caattttcta atttcatcaa caccaatatc
    13321 atcttgacct acatgtacgc catcagcgtc aatttccatt gctaaatcta tatcgtcatt
    13381 aacgataaat ggaacattgt attttttaca aagttcttta atttggatag ctagctcaag
    13441 tttttctaag ccttctaaag caccctcacc tttttctcga aattgaaata aggttatacc
    13501 accttttaag gcttcctcaa cgactgtata tagatttttt ccttggcaag tagtcgttcc
    13561 acaaataaaa tatagtttta gtaattcttt atgaaacatc ttacttcact cttttgaatt
    13621 tcttgacatc ttcatctgta atttcatata aggcatttat aaattcaact ttaaatgttc
    13681 caggaagatg tccatttgga cgtttttccg ccatttctcc agcgatattg taaaccaaca
    13741 ttgctgtttc taatgatttc aattcttgac ctttttcaag tccgataaag cttgctacta
    13801 cagctcctaa taagcatcct gtcccaatga ctttcggcat catagcacta ccattatgaa
    13861 tcgttaccac ttctccatta acagcaatgg catccacttc acctgttact actattggaa
    13921 tattgaactt ctcatttgct gctagagcaa tttcgtcaat attatctacg cccgcactat
    13981 ctactccttt agatgccaca tctattccta ctaaagaggc aatctctcca gcattccccc
    14041 taatcgcagc tagtttgtaa ttgttgatta aatcatctgc tacttttttt ctatattctc
    14101 ctgctccaca ggctacagga tctaaaactg ctgggacatt atatttctct gcaattttca
    14161 gagcagcttg gtataatttc caattttcat ctgtcaatgt tcctatgttt attaataaac
    14221 caccagcata ctttaataag tcctctaaat ctgctggaaa ctcactcatg gctggtgagg
    14281 cgcccagtgc tactaatcca tttgctgtga aattttttac tacatcattg gtgatgcaaa
    14341 tgaccaaagg tgctttttct tttaataatt ttaaacttgt catattgaaa tccttccttt
    14401 tcactttata cgatctacta atttcgattt atctttagtt gagaattttt ttcatttaca
    14461 ttgaatgatt tatactcaat gaaaatcaaa gagcaaacta ggaggctaac cgcaggttgc
    14521 tcaaaacact gctttgagcc tgtagataag actgacgaag tcagctcaaa acactgtttt
    14581 gaggttgtgg atagaactga cgtggtttga agagattttc gaagagtctt acctcatcaa
    14641 atttgtaaat atcatgagcc ttctctagac atcgtaacca atatcaaaaa aagctaattc
    14701 taaagcgact gcttgattcc agcgttgctg aagttctgtc aaatcttctc gatttttacc
    14761 gacacgattg agttcatcaa ccagaaattg aactcactct gcaaagaaag gacctctgtg
    14821 gagattgatc cattccgaat gaatatagac ttcaggtaga gccaaatctt tagaacccca
    14881 gtctaaatag agaccttctg caatgaccag cataaccaaa agatgggcat agtctgatga
    14941 agccactgcc caatacatta gatcctgaaa ggcttttgtt acagggtgca aagtcacttc
    15001 tagatagtta ttctctgcta cttttaactc tttaaaagcc ttttggaaat aaccatcttc
    15061 atctgcttca agaaagccta gttgcttggc aaaacgaagc ttggattcaa gtttatctgc
    15121 gtgagctacg caggcaccca gcatggataa gaaggcatca aagaagtgat aatcttgaat
    15181 cagatagtcc tttaagacct tattctcaat tgtccccgca aaaagttcct taacaaaacg
    15241 atgattgatt gcagcctgcc aatccttctg actgcttttt aataattctc caacagtcaa
    15301 acctggctga aatgcatagt cttgtgtttc catatttact tctcctctct ttacttgtta
    15361 gtaattaata aaacagcaag aaatatcaag caaaatcgta attccacttg atccttttaa
    15421 agcacatcga gagcatttac agagagctaa ctaaacaagc ctatccagtt tatataaaca
    15481 aaaaactcca attacaatca agaattagag ttgacttaca agattagacc gttcatttca
    15541 ccatacgaaa aaactgttca catttccctt cgccagtctt aactgtatca ggttcaatgg
    15601 gtattatctc agcctaaagc accccaaatg tctctattat ttaattactg aaccagtata
    15661 gcaaaaaatg aaagccctag caagatattt gaccgaaaaa tatctttata tacaatatat
    15721 tgaaactaga atagtacacc tctacttcta aaacattgtt agaaatcgat ttaactgtcc
    15781 tgattgattt gtcctattct tatttcattt tactatagtt ttcgatagcg atttattctt
    15841 ccaatacacg aagaaaaacc tccacattca gtgaaggcaa tctgttttat caatacaatt
    15901 ttaagtcacg agggtcaact gggaaggttg ggttgtatgg attgtgacgg agcttaaagt
    15961 gtttgacatc ttcaatggtc tgagctccag acaattgcat aactgtcttc aattccgcat
    16021 tcaagtgttc aaagacttga cgcacaccga cactaccacc gagagccaag ccataaataa
    16081 cagggcgacc aatagctacc aagtctgctc ctgaagccaa ggctttaaag acgtgttgac
    16141 cacgacgaac accagagtca aagacaatcg gcacacgtct atcaactgct tctgccactt
    16201 cttgaagcga gtcaaaggca gctggtccac cgtcgatttg acgaccaccg tggttggtta
    16261 cccagatacc agaagctcct gcagcaagtg aacgttcaac gtcctcacgg cattgtggtc
    16321 ccttgacata cacaggaaga ccagagtatt cagcgataaa ttctacatcg cgtggagaca
    16381 agcgttgttt agctgatttg taaacaaagt ccattgattt accagcacct tctggcaggt
    16441 attcttcaac aatcggcatg ccaactggga agacaaaacc attacgctta tccacttcac
    16501 gattcccccc tacagtagca tctgccgtca agacaatcgc tttataacct tcagccttca
    16561 cacggtccat gatgtggcgg ttgataccgt catccttact aaagtaaaat tggaaccaat
    16621 ggggtgtccc ttgaagggct tcagaaatct ctggaaggtc aacagtagag taagagctgg
    16681 ttgtataaag agaaccaaac tcatgcacac cacgcgcagt cgccacttcc ccctgttcat
    16741 ttgccaattt atgagccgca acaggcgcca taatgattgg tgaagatagt ttttcacctg
    16801 caaattcaat ctctgtactt ggattttcaa catcgcaaag tgtatgagga acgatgagtt
    16861 tgtggttaaa ggcgcggata ttctctctta aagtgaaagt atcttccgcc ccactagcga
    16921 tatagccaaa tgctgcttta ggaataactt gttgcgccat tggctccaaa tcataggtat
    16981 tgatgaagtc tacatgacct tctgcattgc ttgttttata tgacataaaa tgccctcctt
    17041 gattaagtaa gcgtttgctt tttactacac aactataata actctttttt caatcatttt
    17101 caagagtttt gcttaaaaac catcttattt tttcatacaa tatactagcc ctactttcct
    17161 taaactctaa accttagtct atattaagtg aatcgttgag attttttgct gccaggcatt
    17221 tgaactactt ttttatttgc ggattctatc tactaatact ataaaaaaaa caagtgaata
    17281 agacaccaga acatcctcta ataggaccta tggacttata tcagtcccat atatactgtt
    17341 taagcaagat actatcctag ttgacgctaa cttcctatcc cacttattaa ttttttattt
    17401 atagtgaatc tgaacaaatc aattggggaa tccaagtcaa tttctagtac tttttgaaca
    17461 gtttcagcgt actatcgtaa aatgaaataa aacatgcaca aattgattag ggaatttaaa
    17521 ccaatttcta acaatgtctt agaaatcaaa gtgtactatt tcaacttcaa tatactacac
    17581 ttcattttct ccttaaattc agtctctttt tgaatcaaaa atcctctggt aagagccaga
    17641 gggtaagaat ttatttcatt gttgggaaga gcaatacatc acggatagtt gttgtatcag
    17701 tgaggagcat gcagagacgg tcgataccga ttcccaaacc acctgttggt ggcataccgt
    17761 attcaagagc ctcgatgtag tcatagtcga tgcctgtcgc ttcatcatca ccaagttctt
    17821 tagctttagc ttgggcttca aaacggctaa gttggtcgat tgggtcgttg agctcagtaa
    17881 aggcattacc gtactcctta gtcatgataa agagctcgaa acggtcagta aagcgttggt
    17941 cttcaggatt tttcttagcg agtggagata cagctactgg atgtccatag acaaaggttg
    18001 gttggattaa agtttcttca acaaactctt caaagaaggc attgatgatg tgaccaacct
    18061 cagtgtagtg tttctcaact ggaactttct tctcagcagc gatagcttta gcttctttca
    18121 aagtcatgtc ttgccagaaa tcgacaccag taatttctct gatagcatcc accatatgaa
    18181 cacgcttaaa tggttcgtta atcttgattt cagtaccttg gtagttgact gggccatcgc
    18241 ccttaactga tttagcagca tgttggataa tgccttccgt caagtccatg atatcttgga
    18301 agtctgcata agcttggtaa acttcgatag aagtgaactc agggttatga gtagcatcca
    18361 ttccttcgtt acggaagata cggccaattt catagacacg ttccatacca cccacgataa
    18421 ggcgttttaa gtgaagctca gtcgcgatac gaagcaccat gtcaatgttt tgggcattgt
    18481 ggtgggtgat aaatggacgg gcagcagcac caccggcttc attatgaaga acaggtgttt
    18541 ccacttcaag gaatcctttt tggtcaaggt aacgacggat ttcagagatg atttttgaac
    18601 gagtgacaaa gcgttcaaag ctttcacgat tagaaatcaa gtcaaggtaa cgtttacggt
    18661 aaattgtttc aacgtctgtc aaaccatgga atttctcagg aagaggacga agagccttag
    18721 acaagtgtgt gatgtgggtt gccttgatag agagttctcc catatccgta cgcatcactt
    18781 caccttcgac accaaggaag tcaccaaggt ctgctttttt gaagatttcg tagttttctt
    18841 caccgacagc atccttacga acgtagatct gaatctggcc ttcgcggtct tgaaggtggg
    18901 caaaaccaac ttttccttta ccacgtttgg ttaccaagcg tcctgcgata gtagctgttt
    18961 cgtttttatc gtgtaattgt tctttatcga ggttggcata tttatctttt aattcttgtg
    19021 aatttgcagt acgttcaaaa cgttttccga aaggatcgat tccttgttcg cggagcgcag
    19081 ccattttttc acggcgaacg atctgctggt catttagttc ttccatatgt tctgtagaca
    19141 tgggatcctc ctagttttac tcaaaattga atacgatgag tcattttttg cgatactccc
    19201 attttatcat aaataagcaa gaaattcacg gataatcttt aaaaactaaa aagaacctga
    19261 cgctaaaatc actggaaaga agtgaaagta tcttccgccc cactagcgat atagccaaat
    19321 gctgctttag gaataacttg ttgcgccatt ggctccaaat cataggtatt gatgaaatct
    19381 acatgacctt ctgcattgct tgttttgtat gacataaaat gtcctcctta ataagtaagc
    19441 gtttactttg tatattataa aaatatatta actctttttt caaaactttt caaatatttt
    19501 gtttggaaat ttcagaaatt ttatgtctat gataaaaatc cttataacgg caataaaaaa
    19561 tagatattat ccaaagaaga ttttaagtgc tacaataact gtattatttc tagatgggag
    19621 gttctatttt tggattgatc cattgttgaa caatatctac cactatatca aaaggcattc
    19681 tttctgacct tgcatattgc agtttgggga attttgggat cctttctgct cggtttaatc
    19741 gttagtatca tccgacatta tcgaatccct gttttagcgc aagtagcgac agcctacatt
    19801 gaattgtcac gtaatacgcc ccttttgatt caactcttct ttctctactt cggtcttccc
    19861 ctaatcggga ttgtcctatc ttcagaagtc tgtgcaacgc ttggacttgt ctttttagga
    19921 agctcctata tggcagaatc tttccgaagt gggctggaag ccatcagtca aacccagcag
    19981 gagattggcc tcgctattgg tctgacacct ctacaggtct ttcgctatgt ggttcttccg
    20041 caagcaacag cggtggtact cccctccttt agtgccaatg tcattttcct tatcaagaaa
    20101 acctctgttt tctcagcagt ggctttggcc gacctcatgt acgtcgccaa ggatttgatt
    20161 ggtctctact atgagacaga cattgcgcta gctatgttgg tagttgctta tctgatcatg
    20221 ctgctaccca tctcactggt ctttagctgg atagaaagga ggacctgcca tgcaggattc
    20281 gggaatccaa gtactctttc aaggaaataa tctcctgaga atcttacagg ggttgggcgt
    20341 tacgattggg atatccatcc tgtctgtcct cttatccatg atgttcggaa cagtcatggg
    20401 aatcatcatg acctcccatt ctagaatcat acgattttta acacgattgt atctggaatt
    20461 tatccgtatc atgccccagc tggtgctact cttcatcgtt tactttggct tggctcgaaa
    20521 ctttaatatc aatatctcag gtgagacttc agctattatc atttttaccc tctggggaac
    20581 agctgaaatg ggagacttgg tacgtggagc tatcacttct ctccctaaac atcagtttga
    20641 aagtggatag gcactcggct tgactaatgt tcaactttac taccacatca tcatcccaca
    20701 agtcttaaga agactgctac cgcaggctat caatcttgtc actcggatga ttaaaaccac
    20761 ttcattagtt gttttgattg gggttgtgga agtgaccaaa gttggacaac aaatcatcga
    20821 tagcaatcgc ctgaccatcc caactgcttc attttggatt tatggaacca ttctagtctt
    20881 atatttcgca gtttgctacc ctatttccaa actatccact cacttagaaa aacattggag
    20941 aaactaaatg tctgaaacta tcttagaaat caaggaacta aaaaaatcct tcggagacaa
    21001 tcccatcctc caaggacttt ctctagaaat caaaaaaggg gaagttgttg tcatcctagg
    21061 gccatttggt tgtgggaaaa gtaccctcct tcgttgcctc aacggcttag aaagtattca
    21121 aggtggagat attcttctgg atggtcagtc tatcgttgaa aataaaaaag attttcacct
    21181 agttcgccaa aagattggca tggtctttca aagttatgaa ctctttcccc atctggatgt
    21241 cttacaaaac ctcatcctag gccctatcaa agctcaagga agggacaaga aagaagtaac
    21301 ggaagaagct ttgcaattac tagatcgtgt cggtttactg gataaacaac atagctttgc
    21361 tttgctttgc ccgtcaatta tctggtggac agaagcaacg tgttgcaatt gtccgtgccc
    21421 tcctaatgca tccagaaatc atcctttttg acgaggtgac tgcttcgctg gatccagaaa
    21481 tggtgcgtga ggtgctggaa cttatcaatg atttggccca agaaggccgt accatgattt
    21541 tagtaaccca cgaaatgcag tttgcccaag ccattgctga ccggattatc ttcctcgacc
    21601 aagggaaaat cgctgaagaa ggaacagctc aagccttctt taccaatccg caaaccaaac
    21661 gagcccagga atttttaaac gtctttgact ttagccaatt cggctcatat ctataaagga
    21721 gattcttatg aaactattca aaccactctt aactgtttta gcacttgcct ttgcccttat
    21781 ctttatcact gcttgtagct caggtggaaa cgctggttca tcctctggaa aaacaactgc
    21841 caaagctcgc actatcgatg aaatcaaaaa aagcggtgaa ctgcgaatcg ccgtgtttgg
    21901 agataaaaaa ccgtttggct acgttgacaa tgatggttct taccaaggct acgatattga
    21961 actagggaac caactagctc aagaccttgg tgtcaaggtt aaatacattt cagtcgatgc
    22021 tgccaaccgt gcggaatact tgatttcaaa caaggtagat attactcttg ctaactttac
    22081 agtaactgac gaacgtaaga aacaagttga ttttgccctt ccatatatga aagtttctct
    22141 gggtgtcgta tcacctaaga ctggtctcat tacagacgtc aaacaacttg aaggtaaaac
    22201 cttaattgtc acaaaaggaa cgactgctga gacttatttt gaaaagaatc atccagaaat
    22261 caaactccaa aaatacgacc aatacagtga ctcttaccaa gctcttcttg acggacgtgg
    22321 agatgccttt tcaactgaca atacggaagt tctagcttgg gcgcttgaaa ataaaggatt
    22381 tgaagtagga attacttccc tcggtgatcc cgataccatt gcggcagcag ttcaaaaagg
    22441 caaccaagaa ttgctagact tcatcaataa agatattgaa aaattaggca aggaaaactt
    22501 cttccacaag gcctatgaaa aaacacttca cctaacctac ggtgacgctg ctaaagcaga
    22561 tgacctggtt gttgaaggtg gaaaagttga ttagtcatta actcttaaaa ggaactggat
    22621 tttaagatcc aatccctttt taagatttta cctataacat cctgagtcta tctaagatgt
    22681 tcaatctgaa cacagtgtac atactttatc ttctattgca tatactttat cacataagat
    22741 acgaatatcc tcttcactat gactagcaat caaaattgtt gtcccttttt cactagagag
    22801 ctttctaaac aatgttctca tattttctac acttgattta tccaaggcat tcataggttc
    22861 atctagtaaa agaatagagg gattctccat aattgcttga gcaatcccta gctttttcct
    22921 catacctagc gaataagttt taactttctg gtctttttgc tcatatagac caactatttt
    22981 cagtgtatca ttgatttcct gattaccaac tactcctcgt atgcttgcca aatattgtaa
    23041 attcttaaag ccactataat aatttataaa accaggttct tcaatcaaag ctcccaaatt
    23101 agctggaatt tttctctcag gaacaatatt ttccccattg attaacactt ctccataaga
    23161 cggactatat aaaccagcta ttaatttaaa caatacactt ttccctgagc cattcgcacc
    23221 agtaattcct ataatttccc cctgtttaca actaaagtta aggttttgaa aaacacatgt
    23281 tttttttaat tccaactgaa tattttttaa tgtaattatt tcattcattc tataaacctc
    23341 ctcttttgac gagtgaaata gaaaatgctt ttaaaaagaa agactaaaaa tagcaactga
    23401 agaaataaat ctcgtcctat atctccattc cctcgattta aaatataaaa tagataatta
    23461 gttcgatttc ctacaaatag accaccaaac acaatcatga gtaaaaagaa gctaacacaa
    23521 gaaaagttca tttgctcatt cgctcctagt acgtataaca taaagcaaaa caagactaac
    23581 acacaagcat tcaaagaatc aactataaac aaaactccta tatcccagtt tggtaactgt
    23641 aacataaatt gaatcactag aacttttacc atgattaaaa tgagtccata aagaaaacag
    23701 gtccaaatct gatacctaat ccagagctta atagaagaaa atcgaatcac ttccataaag
    23761 aaatcggatg ctcttctacg atatacaact gctagaaaaa atgtatgaat aataaaccaa
    23821 tgaagcaacc atatagataa gactaaaaaa gagttttgac tcagattagg cccttttaaa
    23881 atttctataa caagtctatc atttccttct aaccaatacc ataatcctaa acaaatcaat
    23941 atccaaaaaa gaacataacc ccaaaagtac ttggtataga ttatctgatt caacctccac
    24001 atgtgactac ttaactttcc catttccaac ttttacactc tcctccagtt tctatgaaca
    24061 gaaaatacag tcaatggaat tatgatagat agtaatgtaa gccaataaat caatgcatac
    24121 ggattggaat ttaccatata ctgaaaaatt ggcaataatc caattatccc attgtccaac
    24181 tgataaatcc agaataagga ttctacaaat aaaaaagtaa acagaaatac taagctcatg
    24241 tttgattttt taaaccaaga aaaactgcta atagtaagta aggataaaaa gaaatagtat
    24301 gctatataag agaaaaaaaa tcctataaaa aaactagcat tgtttgcaat acttatacca
    24361 taaaattctc ttaaaaaatc aacctccttt atctccaaag agaagctaaa accattacta
    24421 aatgcaatca gaaaaatcaa taaaaataaa gtcgccgtcc aaatccccgt actaagagct
    24481 gctaatttga aactaaaact ggtaaagtgc ttaattgatt tcagacgaat acgacactcc
    24541 aacctattaa aatagttatt catcaaataa aaaaagaata atatatatgt gaacggaaag
    24601 caatatactc cagtcgtcat atcttgaagt aaaactaaga tccattctaa tacatttgga
    24661 tggattgaat attggcgaca gcgcaataaa tatactgtac tagataaaac acaggatagc
    24721 agtaatataa aataaaccaa tactgctaag aaatcttttt tataaaattg aacaaattgt
    24781 ttcattatac atagtcctct gaatgtagaa aaaatgtacc ataaacaacc aaacaactaa
    24841 caaataaaat aaaagcaaga tgcccactaa ctaaggaaag actgatatct ttctgatatc
    24901 ccaaagctag cgttgtcaca ggttctaagt aagatagccc taaaatagcc cataaaatac
    24961 caccaaccat catataggca actgggatga aaatagctcc taattttttc ttcactagca
    25021 aagcactagc tagtccaaaa atagagaaca cagcgcccca aactccatac cagagagtcg
    25081 tcacaagact atagagaaac tgattggaat caaataattc ttttaaggca ccactataat
    25141 ctccaatata aatttcctga taaggagtca ctaaaagatt aattcctaat aataataaat
    25201 aggggagaaa aaagactaga aaagaagaaa taattgcagt actacctaca atagctagat
    25261 acctcttttt agaaattcgg cacaattgtg ctgttagaaa atgactctca gcatcctcta
    25321 ttatctgact agaatagggc agtgtacaga taagtgcagc tactaggcta atcggtgaaa
    25381 atcctcgaat agaagaagcg gcaaaaaaaa tcgataaacc ttcaatttta taaataccat
    25441 tgaaagcaag gaaatttcct aaactcatgc aaagaagggt caaaaataaa gacatataaa
    25501 accgaggtga ttgaacgact cgtacaagat tacaaatgaa aaattccatc cttactcctc
    25561 cttataataa aaatagggtg tagcattctt ttttcatgct acacccacaa tcaaccatct
    25621 ttaaggctta ctctgacaag taagttaata agaatctgga ctccaagaac ctgaagtatg
    25681 aattcttaca taatttccaa attgtggcgc catagctaat ctagtaccag aaccaatata
    25741 attgtcacca cctccattat agtacatgac aatcctagag ccagacccca atgaatatac
    25801 cggggtaata tctgacccac tataggcgct acgaatagag gtatttaacc ttttaccgcc
    25861 accagtgctg tcactattat taattccagc agaggcgttt tctttctcaa gctcactagt
    25921 tgtatccgaa ccccaacgcg gcaacgttaa atcataattt ccaatctgtc tagctaaaac
    25981 tgtagggaga aacaaactag atgcaattgt aactacgcaa aaaaggaata tatttttctt
    26041 cttttcatga catcgtcctc ttaagaagtg ataaacaaga tagttgattg atcaatttga
    26101 tacatattac attttcatta tatcaataaa agaaagcgtt gtcaattatt ttatttaaaa
    26161 tattgtcata ttttaaataa aatggtaaaa gagactcggt agcctcgtct ctctttatct
    26221 tactgaccta accttcttgc caattttctt ggtcttcttt aaagcgtttt agaagatcaa
    26281 ggccctctgg cgtgatgtaa ccttcttctt gggctagatg gataagctcg ctatagtttg
    26341 aaagcgtcac aagtttaaca ccagcatctg caaagttctt atctgctttt ggcaattggt
    26401 agctgaaaat cgctacaact ccaagtacat ctgctccttc tcgcttggct gctgctacag
    26461 cttcaagaac tgaaccaccc gttgaaataa ggtcttcaac cactaccatt ttttgacctt
    26521 gagctacgcg accttcgatt tgattaccag ctccgtggtc ttttggtttg ctacggatgt
    26581 aggcaaaagg caagtccatc ttatcagcaa taatggctcc gtgtggaatc cctgctgttg
    26641 cagttcctgc aatcacttct acttcaggaa aggcttcttt gatagcttcc acaaaaccat
    26701 tttcaattag ggtacgagtt tctggatagg ctagtgtcac acgattatca gtgtaaatcg
    26761 gtgacttgat accagatgcc caagtgaagg gttcctctgg tttgaggtaa acggcttgga
    26821 ttttcaagag gtggctagcg atatctttag caagtgtcat ggtattctcc ttttattttt
    26881 ctaatctagt tctttaattc cagtcctgtg tccattcatc cttgatggca tgataagctg
    26941 caacaggatc ctcagcttgg gtaatgggac gtcccactac gatatagtca ctgccgattt
    27001 gataggcatc agcaggtgtc atgactcgtt tttgatctcc aactgcaaca ccagctggac
    27061 gaatccctgg tgtcagacag ataaaatctg gattggtagc ctgcttgatg acttgtactt
    27121 cctgagccga gcaaacaaca ccatccaagc cagcttcagc tgtcttcttg gcatagtgaa
    27181 tcacagactc ttgcagactg gtttggatat tttgaaactc ctgcatctga gcttctgacg
    27241 ttgatgtgag ctgcgttaca gcgatcaatt tggcttgact cccaagacct tcacgcgccg
    27301 ccttcatcat ctctacacca ccagccgcat ggacattagt catatcgaca ccaagctgag
    27361 acaagacctt catggctgac ttgactgtat taggaatgtc atgaagtttg agatccaaaa
    27421 agacactatg acccaaacct tttaagtagg acacaatctc aggccccgct gcgtaataaa
    27481 gctccatccc taccttgaga taaaggcttt cttctgctgg gaaaagagct aaaaattcct
    27541 tgaccgcctc aaaactagga aaatcaagag caatgattgg acgatgttct cgcataggtt
    27601 tctcctttta cctttactag tgagagagtc tggccaacag aagccacgaa aaaaggaacc
    27661 tgccaacagc aaggttccac gaaaaatggg tagtctccac cctttcaccg tctaacctta
    27721 gctgcctctc tggactgctt taaaggtttt ctattattct attatttcta ctagcacttg
    27781 tcaagtaaaa acatggtcac taaagaacta taagagaaaa ggtaaaccta gcgacgcgat
    27841 gagcgctggg tcgtttgatt tcgattgctc tcttcctctt gttttttctg ttcttcttcc
    27901 tgttttttct cggcttcctt ggcctcttgt ttggcttttt cctcagcctc cataattaat
    27961 ttatccgcca cagtgtaact gtaaattcca gcttccatgt cgaccacact cggttctgac
    28021 aattgtggct taatcttact gtaatatggc agtttcttac tcatttcaga tagaggaacc
    28081 aagacttcgt ccgaatcatt catggtcaat cgaattaaat cggatgtcac cttgcttggg
    28141 gctaattcca ccttttggat agccgccttg agttctgggc taatttgagc aagttctgag
    28201 acaaaaacct tgatttgttc actatcatta aagagaactg ataaataagt ttctggtaaa
    28261 ctgttcagac tcacagaact agtctcaagc tgaccactgg aaagaatagg ataatgattt
    28321 tcaccagaaa tatagtaggc cacaatatca tattccttga ccttaatagt gaacttagtt
    28381 ggaaattgat agacaagttg agctgattca acccaatagt tagacttaat ctgcttttca
    28441 tattttgcct tgtctagcag aaggttaatc gtataatccg aatcctgaat gcctgaagcc
    28501 tgtcgaatat catcagctgt agtttgcacc gttccctcaa cacgaatatc tttcatggtc
    28561 gcataaggac tgagcaagta ggcagagaca atcaataaaa gcagacttgg aaataaaatc
    28621 gtgaaggctc gcaagatatg gataccagga atctttgctt tggctggttt ttcctttgta
    28681 gcctttttag aaagcttttt atcctgttcc tccttctctt tagactctgg ttcttctttc
    28741 tcttctttct ctttgtcagc ctctgaggat gctacttttt cttcagactc ttccttagct
    28801 gattctgaat cttcctggtc tgtttcactc tcctggtcct gtttgtcctc tgacttctca
    28861 gattcttctc ccattcgagc ttgtctttcc ttttccttct cctcagctag agccgcctct
    28921 tcttcagcct tcttttttag atattcttgg tttcgtttct gccattctga taactctttc
    28981 aattcttcga ggatttcttt gtcctcattt ttcttatctt ttgacattta ctttccttat
    29041 gataaatctt ttttcaacaa ttgataaaaa tctgctagag atttcaattc cttagaagcc
    29101 ttcatcttag cttggtaatc ttccttgtga cttagtaagt gagaaagctt ctcttccaaa
    29161 ctatccaagg tcaaatcgct ttcttgaagg tcttctgcat agcctttttt tacaaagtaa
    29221 gctgcatttt caagctggtc accacgacta gcttcacgac caagcggcac aatgacatgc
    29281 aattttgcta tcgccaagag ctcaaaaatc gtattggcac cacctcgtgt cacaacaata
    29341 tcagccaatt ccatcaaggg ttgatagaga tcggtcacat agtcaacacg aaaaagattt
    29401 tggctcaact cattcaggct agaatctcca gttagattga taatattgta gcgctctgtt
    29461 agttctttct tatggtctgt caccaattgg ttaaagacac gagcacctgc agaaccgcca
    29521 acaaacaata cagtcggcaa tttatgatta aagtggcttt gaatatccac caattcatct
    29581 ggttctggat ttttttgatc tgaaaccttg gtcactgctc ccacatgctc aaccttagac
    29641 aaactcgaag cttgctcaaa ggttgaatac atcttagtcg caaatttata ggcgatttta
    29701 ttggccaagc ccatagacag gtcagattcg tgaataaaga caggcactcc tgacacacgc
    29761 gcagcgataa caggcggtac tgagacaaag cccccctttg aaaaaagggt ctgtggacga
    29821 agtcgcaaca tgataaagag cgattggacg attccccagc aaactttgaa gacgtccagc
    29881 atattttgcc aagagaaata gcgacgcaat tttccagtcg caatagaatg gaaggtgaca
    29941 tccaaacctg acttaaggat ttcttggtgt tcgataccac gcttgtcccc gatatagtgg
    30001 acttcccaac catcttcgat gaacttgggc attaacaaaa gattgagggt aacgtgtcca
    30061 accgtccccc cacctgtaaa gacaattttt ttcatattat tcttttaact ccgctactgt
    30121 gtcgataaag aggtcgccac gtacttcaaa gttagcatac atatcccagc tggcattggc
    30181 aggactaaga agaaccacat ctccttgagt cgcaagctca taggccttgc gggtcgcatc
    30241 tgcaatatct gtcgcctcca cataagcgac accagccttg tctgctgccc gtttgacacg
    30301 ttctgcagat tgacccagga tgaccatctt cttgagtcca gtaatgtctg gcaccaattc
    30361 gtcaaactca ttgccacggt ccaaaccacc tgcaatcaag acgaccttgc tgttatcaaa
    30421 tcctgacaag gctttttgag tagccaagat attagttgat ttactgtcgt tatagaattt
    30481 aacacccttg atgtcatcca caaactggag acggtgtttg acaccaccga aggctgaaag
    30541 agtttccttg atggtttgat tgtccacacc acgaagcttg gctacagcaa tagtcgcaag
    30601 ggcattttcc acattgtggc tacctggaac accgatttca ttcgctgcca tgactacttc
    30661 accacggaag tagagttgac catcttccag ataagctcca tcaacctttt caagtgttga
    30721 aaatggtaca acagtggctt ctgtcttgga agtcaagtct tttgccaagt cttgattaaa
    30781 gttcaagaca aggaaatcag ctgctgtcat cttgttctgg atattccact tggctgctac
    30841 atattccgaa aatgacccat ggtagtcgat atgagttggc atgaggttgg taataaccgc
    30901 aatctctgga tggaattctt gaacacccat gagttggaaa gaagaaagtt ccataacaag
    30961 cgtgtcctta tctgatgcta tttgagcaac ctgactagct ggatagccga tattccctga
    31021 taaaagacca tgttgcccag cagcagtcaa aacttcccca atcatagtcg ttgtggttgt
    31081 cttaccgttc gatcctgtga taccaataat cggtgcttct gaaatcaaat aagccaattc
    31141 cacctcagtc aagactggaa ttcccttggc caaagccttt tcaatcatgg gattgttgta
    31201 ggggatacct ggatttttca ccataagggc aaactcttca tccaagagtt ccaaaggatg
    31261 gccacctgta atgaccttga tcccttcttc cagcaaactt tgggcagctg gattgtcctc
    31321 gaaaggtttc ccatcattta ctgtcacaat ggcacctagc ttgtccaaca aacgagctgc
    31381 agattcacca gacttggcca aacctaaaac aaggactttc ttatttttaa attgatctat
    31441 tactttcatg tctcgaactc catttctact cctactattt taccattttt atggaaataa
    31501 aaaagccaca aagtgtgttt gtgactcttt cttctaactg aatcttacca tatcatctat
    31561 gtgataaatc ggtaactcga atgacctgat ccacttgttc ccaaatcaga ggattgtggg
    31621 tcgcaataat aatggtccga ttcggatttt ttaaagattc taggatggaa agtaattcct
    31681 cagagttttt ggggtctaag gaagtggttg gttcatctgc gaggatcaaa ggtggatcct
    31741 ttaaaattat cttcgctaat gcaacacgtt gtgcttctcc tcctgataac tcaaatatag
    31801 gttgcttcaa atccaaataa gagaggttta cacagtttag agcttgtttc atcaaagaga
    31861 ttttctcttt ttccttcaac tttttaccaa ctaaacccag attgagattc tctttgacgg
    31921 tttggctttc aattaagcca aaatcttgaa ataagtatcc caagtaatct ctaaagaaaa
    31981 cagaaggctt gatgtcctta agagaagtac catcatagat gatttgtcct ttgtcatatg
    32041 gctctaatcg tccaatcata ttcaagaatg ttgtcttacc acagccactt gtaccgatta
    32101 aggcataaat tttcccacct tcaaaatgaa gatttgtatc tgaaaatagc tgacggcttc
    32161 caaatttttt agatatattc tttagttcaa tcatcctatt ttcctttcat aattgtcata
    32221 gaaacacgag attctttctg cgcttgacgg taaagcgtca gaactgcact agctagaaag
    32281 actaataaag tgagcaagcc aatcaccaag tctcgactgc ttaaaataaa gagactagca
    32341 ccaaatacaa aactggcaaa ttgactaacc atatactgag catgtgtttc aaaaaatcgt
    32401 aaacctgaaa ttcgtttaat caaaatatct cggcggaatt gctcgaaata tagaagattg
    32461 acagaataaa atagtaacaa ggaactagct atccccacaa tagctcctaa gattaaagtt
    32521 gctgtttcag tttgaacttc attataacga gttagataaa cacttcttcc ttctttaaga
    32581 taggatactt gctcataaat tccagctttc ttcaagagtt ctagcccact ctcatatcct
    32641 ttgataaaga gttgttttcc agcattgata gaccaactag ataaggatat aaaactatca
    32701 cctgtagaag tcggcgtgaa taccactaaa atcggatcag tcaaatactg agtagatacg
    32761 ggattctcac cgttattata aacaaaccgc ttttccccca ttgaaagata actaacgtgc
    32821 gctttcatct cataatccaa aggagcactt gcctcctcac cagattttcc ataataactc
    32881 aatctttctt caaaaacttt cttaagttct gcttctcgag agcgcaaatg ttctgggagc
    32941 aagaggataa actcaccttt ttggagatgg gctaacttct gtttggtctc agcatctacc
    33001 acgacctttt ccttgtccaa ataactggga ctaacataga gcgtattagc atctggacta
    33061 taggtatcca gtgtctctcc ctgttcattt tttccttgtg gattggcaaa atggagcaga
    33121 ttatccttta cataaagagc ttgttcttct tcgattgctt ccttggcaaa ggcataccac
    33181 ttgctctgat tttctgtatc ttttcctcta tcacctaagc caaaagaaat ttgataatag
    33241 tctgctctat cctgccatgc ttgttttgaa atttcaagtt ctttcaatcg ttggtaagac
    33301 atcaaacctg tcttaacagc gtagcctact gtaaagacag caaccaactg acacaatagg
    33361 gttaaaatca tcaggcgttt aaggggtaat ctccccttaa taacgggaac taatgctttg
    33421 taactcaaac tcattagata aagaagcatt agtaaaattg aaatcgccaa taaaaacaac
    33481 agatagaaac taatcccaaa accataggtg gctaacaaga taggataaaa caaaccttga
    33541 ctaaaaagaa cgactccccc acctaggaag gaaaggaggg ctgatagaag gagccatttg
    33601 atatcagtag ataaagaatg ccccatgatg gataagagag tctgaccaga aaagagtttt
    33661 atacctgctg ctctcatttc cttaatccga gtgataatca ctaaagcaaa gaaagataag
    33721 ccaaatattg ctaaactaat taaaataagg ggatttagta atattcgaaa agcaagaaaa
    33781 tagggcggta tctttcggtc agcacttgct ttataaccca aatctcctaa tttatcggca
    33841 agcttttctt tcgtcaagga gcctgacaaa aggagataac tatttagcgg atcactacgt
    33901 tcacgacttt cttggctagc ttcttggaat tcttttggta aagttccctg accataagtt
    33961 gcataagtaa agtgagtcgt cccatcctta ctcggctcta caattcttct agctattaaa
    34021 ctctgttctg agtttgcaaa attctccaat tcctgttcaa atacctcacg cgtcggttcc
    34081 tgagtatctt ttttgacacg aagtaaagaa acggaatcat agcttgcata taaatattgt
    34141 ggcgcacgta agacaataat ccaagcaagg aagaagctga gaaaaaagtt gataataata
    34201 tgaatagttt cttcatagta gactccttgt aaacaaaatt ccccctgtaa tttcttacaa
    34261 ggggaacgat ttaaatcaat gaacgattag tcataatcac agtaaaatgc tacttgttct
    34321 ccccatttag tccaaatcca tgcataggag gtttttccag cagaagcttc tcctttatct
    34381 gaatgactat tccatctact tacaagagaa gaataatgat attttttacc atgatagtaa
    34441 tttgaaaaag cccaaccacc tcctgaacct tctccatacg tccatactcc tccatctgga
    34501 tattgtacag cagctgatgc agctcccaat aatgtaaaac ttgaaataag agctagagca
    34561 agtaatctat gttttttcgt tttcatttta ttttttcttt caaaaaaagc acaccttgag
    34621 caacaatgca acaaaataaa ccctcctctc tcttttgttg aaaccgcttt cttatgtgat
    34681 aaaaatatca tttttattat ttgttgtcaa ggaaaaaatc gaatttttta gatattttac
    34741 tacattgcct ctatgaataa tattatatag tagttttatt ttaaaataat atgcaaccag
    34801 tactaaccaa atataaaata gatgccatta acgaatttta ttcaagtttt tcccattcat
    34861 actatccaag caaaagagat gatgttatag tacaaaacaa ttcaaactat tgtaaaattc
    34921 ctagcaaaaa agagagccaa aactctcttt tttatcttct tttacttttt ttgactggca
    34981 tgagtgtaat gtctctaaca ctaaagtaag ctaggatcaa catggctatt gctaggaata
    35041 tttctgttgg taattgaaaa attttcagaa aagatagaac caataaaatc aagagtgcca
    35101 ctaaaataca taccatagcg acgatattga ctgtcccttt aatgctttct ggtgtcgcaa
    35161 atacatagag taggagcagt aaaattccta ggactaaata gaccatcttt ctctctttct
    35221 agctcttatt cagctgattt tttcttcttg ttagctttct cacgctctgc tttgttaagg
    35281 atttgtttac gcaaacggat agactcaggc gttacttcca tgtactcatc gtcgttcaag
    35341 aactcaagag actcttcaag tgtcaagata cgaggcgtct tgataacagc tgtttggtcc
    35401 ttagtagctg aacgaacgtt ggtcatttgt tttgccttcg tgatgttaac tgtcaagtca
    35461 ttttcacgag agttttcacc gatgatcatt ccttcataaa cctcagtacc tgggttgaca
    35521 aagatcgtac cacgttcttc gatagacatg attgagtaag ttgtagcctt accagcatcg
    35581 atagaaacaa gggcaccacg gtgacgtcca ccaatttccc ctggaatcaa tggcaagtat
    35641 tggtcgaagg tatggttcat gataccgtaa ccacgagtca ttgacaagaa ctcagttgag
    35701 tatccaatca aaccacgcgc tggaacaagg aagaccaaac gagtttgacc attaccagtt
    35761 gaaatcatat ccaacatttc acctttacgt tcagaaaggc tttggataac agacccttgg
    35821 tattcttctg gagtgtcgat ttgtacacgt tcaaatggtt cacatttaac accgtcgatt
    35881 tcttttacga taacttctgg acgagatact tgaagttcat agccctcacg acgcattgtt
    35941 tcgataagga ttgacaagtg caattctcca cgtcctgaaa cagtccattt atctggtgaa
    36001 tcagttgggt caacacgaag ggaaacgtct gtttgcaatt ctgcctgcaa gcgttcttcc
    36061 accttacgag aagttaccca tttaccttct ttaccagcaa atggtgagtt gttgaccaag
    36121 aaagtcattt gaagagttgg ctcatcgatg tgtaggattg gaagagcttc tactgcatct
    36181 gtcggagtga tggtttcacc gacaaagatg tcttccatac ctgaaacggc aatcaagtca
    36241 cccgctttgg cttcttggat ttcacgacgt tccaaaccaa agaaaccgaa gagttttgta
    36301 acacggaagt ttttagttgt accgtcaagt ttagaaaggg taacttggtc cccaacctta
    36361 actgtaccac ggaagacacg accgataccg atacgtccaa cgaagtcatt gtagtccaaa
    36421 agtgacactt ggaactgcaa aggctcatct gagttatcta ctggagctgg gatatggtcg
    36481 ataatcgtgt caaagattgg tgccatagtc gcttcttggt cagctggatc atctgacaat
    36541 gaagaagttc cgttgatcgc tgaagcataa accactggga aatcaagctg gtcgtcatct
    36601 gcaccaagct cgatgaaaag ttccaagact tcatccacta cttctgctgg acgagctgat
    36661 ggcttatcga ttttgttaac aaccacgatt gggacaaggt cttgttccaa ggcttttttc
    36721 aatacgaaac gagtttgtgg catggttcct tcataggcat ctacgaccaa gacaacaccg
    36781 tcaaccattt tcatgatacg ctcaacttct ccaccaaagt ccgcgtgtcc tggtgtgtcc
    36841 ataatgttga tacgagttcc gttgtaagca acggcagtgt ttttagcaag gatggtaatc
    36901 ccacgctctt tttcgatatc gtttgagtcc atagcacgct ctgccaattc agtacgtgca
    36961 tcaagcgttt ctgattgttt caataattcg tcaaccaggg ttgttttacc gtggtcaacg
    37021 tgggcgataa tcgcaatgtt acggatatct tctcttaatt ttgtcatgat ttcctctata
    37081 atattcaaaa tttattttct aactgaacga ttataccata atttcaaata aataacataa
    37141 ctcaagcaag tgtaaatgtt ttcactccgc ttttcttttc acgtcaagcc ttttcaaagc
    37201 aagcgactta tgataagata ggcacagtat gcgtttagat aatttattag cccaagaaaa
    37261 agttagccga aaggccatga agcaagcact cctcagaggg gaaattctag tcgatggttg
    37321 cccagcccgc tccctagctc aaaatatcga tacaggacta caagaactcc tttttcagga
    37381 tcgaatcatt caaggctatg aacacaccta tcttatgctt cataaacctg ctggtgtcgt
    37441 tacagccaac aaagacaagg aacttccgac cgtcatggac ttgcttccat ctgacatcca
    37501 gtctgacaag ctctatgccg tcggccgact ggaccgagat acaacaggac tccttctctt
    37561 gaccgataac ggtcccttgg gcttccaact cctccatccc caatatcatg tcgataagac
    37621 ttatcaagtt gaggttaatg gacttctaac acctgaccat atccaaacct ttcaaaaagg
    37681 aattgtcttt ttagatggca ctatctgtaa acctgcaaga ctagagattc tatcagcaag
    37741 tccttccctc agtcaagcct ctatcaccat ttcagaagga aaatttcatc aaatcaagaa
    37801 aatgttcctc tcggttggtg ttaaggtgac taacctcaag agaatccaat ttggggactt
    37861 cacattgaac ccagatttag cagaaggtaa ctaccaccct ttgaaccaaa aagagttaca
    37921 aatcattaaa aactatttag agatgagtcg ataaaacaaa aaaagcttta aaactaaagc
    37981 ttttttcttt tatttaccga aaaattaagg cgattgctac aatccagtta actacagaaa
    38041 tcacaattcc taagatatta agaatctttt ctattttata gtctaattgt gactcttttt
    38101 ggtatgaaat agccaagacc aatcctatga tacccaaaat caggcctaca attggaaata
    38161 acaaaccaag aataatcgac aagataccca caaaaagtgg atttttcttc ttttctttca
    38221 tgttctaaga actctttaaa ttttatacaa attaattata ctataaaaca atagcttcat
    38281 tctatcattc gactaatttg gaaataaggt tagctagtct tcactttccc tttccaagaa
    38341 tccaagccat aagaaaggat ataaatctca gaaaaacctt gttttttcaa gtaaagagct
    38401 gcatttgtaa ctcgttgcgc acgttggttt tcgtagagaa ggacaggttt atctttacga
    38461 agggctgcaa gactagtttt caactgactt gaaggaatat tgcgtgcacc aaggatatgt
    38521 tttctgtgga attctgctgg gtcgcgcaaa tcaatcaatt gacccgtacg aatcaaggct
    38581 tcaaactcct cattgtccac aattttagcc gcacggcgaa tacgaagata gttaaagccc
    38641 atccacgcca acattgctag tataagtgcc cacaaaatcc aagtaaccat tagttctttt
    38701 ctccattttt ctcaatataa tccaattcta ccttgtgctc tctgcgaaga actgcttctg
    38761 cctctagata gtctaattta tccatcaacc ctgcatcgta aatccgagat agttccaact
    38821 tcatcagttc aatatcatat aagcgttttc ccatgtaaac aataatacca aatcgtttga
    38881 ggaattgctg cacatcatag aatgttttca taagactcat tctagcaaaa ttttgtgttt
    38941 ttttcaagaa gagactcaca caatgctcct tattttccta tcttctttag cgattctaag
    39001 gcaagtatgg tacaataaaa acatgagaat tcaacaatta cattatatta tcaaaatcgt
    39061 cgaaactggc tccatgaatg aggcagccaa gcaactcttt atcactcagc caagtctctc
    39121 caatgcagtg cgagatttgg aaaatgaaat gggcattgag atctttatcc gcaatcccaa
    39181 gggaatcacc ttgacccgtg atgggatgga gtttctctct tatgcccgtc aggttgtcga
    39241 gcagacccag cttctggagg aacgctataa aaatcctgtc gcccaccgcg aactctttag
    39301 cgtttcgtct caacactatg cctttgtggt caatgccttt gtctctttgc tcaagaaaag
    39361 cgatatggag aaatacgaac tcttccttcg tgaaactcgg acttgggaga ttatcgacga
    39421 cgtcaagaac ttccgcagtg aggtcggggt cctcttctta aacagttaca accgtgatgt
    39481 tttaaccaag atgctggatg acaatcacct gctagcccac catctcttca cagcgcaacc
    39541 gcatatcttt gtcagcaaga ccaaccctct ggcaaagaaa gacaaggtga aactgtctga
    39601 tttggagaat ttcccttacc tcagctatga ccaagggacg cacaactcct tctacttttc
    39661 agaagagatt ctttctcagg aacaccacaa gaaatccatt gtggtcagtg accgtgccac
    39721 cctctttaat ctcttgattg gtttggatgg ttataccatt gcgacaggga ttttgaacag
    39781 caacctaaac ggagacaata tcgtttctat cccactggat attgatgacc cgattgagct
    39841 ggtctatatc cagcatgaga aaaccagcct atctaagatg ggcgaacgct ttatcgacta
    39901 tctactagaa gaagttcagt ttgatagttg agaaatgata agaaccaata tgtaggctag
    39961 caacaacctg cacattggtt ctttttactt ataattaaaa gtttcccctg ccaacttatc
    40021 agctagcttg ggaaagagag tataaaactt atgggctagg ttcaacaaaa tcgggagatt
    40081 gagttctcgt ttatttttgc ctataatctt gacaatcttt ttagccactg catctgcctc
    40141 taagaggaag cggtcaaccg atttaagata agttccatct gggtcagctt ggtcaaaaaa
    40201 tcctgttcgg attggacctg gattgactgt tgtcacatag actccatagg gcataagttc
    40261 gagtcgcaga gcatttgaaa aaccaatagc cgcaaacttg gtcgctgagt aaagactaga
    40321 cttgccagta gctattagac ctgccatgct gacgatgttg atgatatgcc ctttgctgct
    40381 ttccttcata cgagccgcaa ggtgacgaga cagattcatc agggcaaagg tattgacctc
    40441 aaacatctgg tgaatatctt tatcagcaat ctggtcaaat ccctcaaaaa tcccgtaacc
    40501 agcgttgtta atcaagacat caatcttgcc atagcggaga taaagatcag ttaccagagc
    40561 ttctagggct gaatcgtcgg taatatcaat ttcaatcaat tctgcatggg aataatttcc
    40621 gtagagttgg gctaattttt ccttatttct accaagcaag atgagttggt cattgggcag
    40681 gagtttgacc atttcttgag ctagaccacc gctagctccg gtaatgagaa tagtaggcat
    40741 acttatcctt tctgtgactg ctagatttcc acttcttcca agtctttgac cacatggaca
    40801 ttttcaaaaa ttgtggcagc gtccttcttg agtttgctta tatcttttga gaggaaacgg
    40861 gcactgatat ggttgagtag gaggcgtttg gcacctgctt ctaccgctac ttgtgcagct
    40921 tgcatattag ttgagtgacc atggttacga gcaatttttt catcaccctt gccataagtg
    40981 gactcatgaa ctaggacatc tgcattgaca gccagacgca cactggcatc cgtttttcga
    41041 gtgtctccta aaatagtgat aatcttacct ggacgtggcg ctgagatata gtctgctgcc
    41101 ttgatttcag ttccgtcttc caaaacaaga tcctggccgt ttttgatttt accaaaaagc
    41161 gggccgaacg gaacaccagc agccttgagt ttttcagcat ccagcgtccc ttctagatcc
    41221 ttttgcatga cacgatagcc aacacagaaa atagtgtggt ccagctcctc tgcatacaca
    41281 gtgaatttat cggtttcaag aattttaccc agagaatctt ggtcaaactc atggaaatga
    41341 atgcggtagg gcagacgaga acctgacaca cgaaggctgg ttaagacaaa tgacttgatt
    41401 ccttgaggtc cgtagatttc caaatctgtc tgctcttcat tggcctgaaa ggcacggcta
    41461 gaaaggaaac ctggcaaacc aaaaatgtgg tctccatgca gatgggtaat aaagattttg
    41521 ctgaccttac gtggtcgaat tgtggtttcc agaatgcgat tttgcgtacc ttctccacag
    41581 tcaaagagcc aaacttcgtt aatctcgtcc aaaagtttca gggcgagact tgaaacgttg
    41641 cgggctttag agggctgacc agcccccgtt cctaaaaatt gaatatccat tcgatacttt
    41701 ctaattaatc aatatataac atggctgtgc ggttttccga tcggaaatag cgtttgccag
    41761 aaaaagcagc agcttcttgc aataaatcct cttggctgta gcctttgaga cgttttcgac
    41821 catcagccaa tctttccaaa tcagtcaaag ctgtgagact ttctaggctg acaacttcct
    41881 cgtccttgac aggtttcatg taaatcttac cagactcttc aaagactaat tgatgggaga
    41941 aaatttgcgc aatttcaaag agcaagtcat ccgagatttt ctcctcattt tcagagaaaa
    42001 tccgaccaag gccgtcactc tcataacaaa aaccaaagga tttaccagac agattaagcc
    42061 gaataaaagg cttattttct agggtgaaac ttggctcagt attgtaaaga ttcagttcct
    42121 gactgagttc tgcaaaataa tccgtcgcag cctgaggact ttttttctga tagagttctg
    42181 caaagtaggc attaacaaca cttggcggag gtgtaataag tgttaactgc tcctgctctg
    42241 ttttaccagc tagaagctga tccagataga ccttgtccag acttgtataa cctccatact
    42301 ttagagccaa agttttaata tcagtcataa aattcttcta acctccattt atttttctcg
    42361 gaaatgtagc ctgtaatcac ttcgccgtct tcctgataat cacgttcttc cagaattgca
    42421 acactctcta aatcatgaat cttgtaggac tttgaaaaag gcactcgcag ggtaaatgct
    42481 tcaaaaattt ccttaatctt atctagcaat aatgcttgca agttttcacg actgtcctca
    42541 gacttggcag aaatgagggt atatggcgtt tgggtaggcg tgaaatcctc caccaaatcc
    42601 gctttattat aaagcgtcaa gtgaggaata tcttccatgt ccaggtcttt catgatggag
    42661 agaaccgttt tttcatgctc ctcgtggtaa ggattgctag catcgataac atgaaccaga
    42721 aggtccacat gcttgctttc ttccaaggtt gacttgaaac tggacaccaa ctctgtcggc
    42781 aaatcttgga taaagccaac ggtatctgtc aaagttactt ggagattgcc tcccagatga
    42841 atactcttgg ttgtcgcatc cagagtcgca aagagctcat ctgcttcata ctgggtctta
    42901 ctggtcaaga tgttcatgat agttgatttc ccagcattag tataaccaat caaaccaatc
    42961 ttaaaagtgc tagactccaa acgtttttct ctgacagtcg cacgattttt ctcaaccacc
    43021 ttgagctggc gctcgatatc cgtgatttga ttgcgaacgc tacgacggtt cagctccagt
    43081 tggctttcac caggaccacg ggaaccaatt ccccctgcct gacggctgag cataatcccc
    43141 tgaccaacca agcgaggcaa gaggtatttg agttgggcta ggtggacttg gagcttccct
    43201 tcatggcttc gagcccgcat ggcaaagata tccaaaatca actgcatacg gtcaatgacc
    43261 ttaacaccga gaacttcctc tagattgaca ttctgccttg gggtcagacg gttgttgacg
    43321 atgacagtag tgatttcttc tgcatccacc ataagcgcaa tctcttccaa cttaccagag
    43381 ccgacgaagg tcttggaatc atatttttca cgtttttgtc tgtagctatc tacaacgact
    43441 gcccctgccg ttttcgctaa actagccaat tcttccatgg agaggtcaaa actgtccata
    43501 ccctgcaatt ccacaccaat cagcaggact cgctcctctt ttttctccgt ttcaatcatc
    43561 taaaaactcc tctatctggc ttaaaatgcg gtcttgtaca ccagattctc caatctgata
    43621 aaaggtgacc tgcatgcgat tacggaacca ggtcagctga cgcttggcaa aacgacgggt
    43681 cgcctgttta agactctcac gagcttcctc aaaggtctgc tctccacgga aataaggaaa
    43741 gagttcctta tagccaattc ctttagcagc ctgtacatta ggggaatggt caaacagcca
    43801 cttggcctca tccaaaagcc cagcctcaaa catcaaatcc actcggtggt tgatacgctc
    43861 ataaagttga ctacgttcat catccaagca gataatcagc ggttcataca aaatctcttg
    43921 attttccaaa tcctgaccaa aatgggcaat ttctaaggca cgcatagcac gacgacgatt
    43981 aaactgggga atctcaaggc ctgcttgctc caccaaatgg gctaattcct catctgaata
    44041 tggctccaaa ctagctcgat aagctaaaat ctcctcatga ggagtctccc cacctaggtg
    44101 gtaaccttct agcaagctct ggatataaag tccagtccca ccggcgataa tggctagctt
    44161 gccacggctg tgaatatcct caatagtcat cttagcttct gaaacaaaat caaaagccga
    44221 gtaagactcg gttatctctc taacatcgat taaatgatga ggaacagctg cctgctcttc
    44281 tggactagcc ttggccgtcc caatatcaag tcctcgatag acttgttggc tatctccact
    44341 aaccacttcg ccattaaagc actttgcaac ttcaatagct agagccgtct ttccaacagc
    44401 agtcggtcca acaatcacaa ttatttttgt tttcatcttt tttccttgaa aaattcccat
    44461 tttttcgtta ctattattat aacacaaaaa ggtcagtcag aaaaatgtga cctcttgagg
    44521 aggctggctg attgagaata taaaggagga agactcatgg ctaaaggatt cgctaaaggt
    44581 cttgtaacag gtgtcgcagg aactgtcgct gccgttgcag gtgcagtata cgcatttaaa
    44641 aagaaagtaa tcgaaccaga agagcaaaaa gcagctttca tcgaagaaaa ccgtaaaaaa
    44701 gcagctcgtc gccgcgtatc acgttaagaa acaaaagaag ttgggattat tctcaacttc
    44761 ttttttctat tcttttaaat agctaggtca aacttcaact gtggcttaac agggtcataa
    44821 tccaccaact caaaatcttc tgctttgata tcaaagaaat tagtcccatc aggaacattt
    44881 aaaaccaagc gtggttggca gtttgacggc tcccgacgga gcaattcctg agcttgttca
    44941 aattgattat catagatatg gaggttgttg atgaagtaga agaacttccc aaccttccag
    45001 ccaaaatgtt tggcaatcat catctgcaaa gccacatact gcatagcgtt gatgtggtgg
    45061 gccaccagca tatcattgga gcgctgggtc aaggtcgcat ccagatagat ttccccatca
    45121 acacgccgga catcaaacat ggtctgaaag gcgcacggga gcagcccatc tgtttcttcg
    45181 aaagcttggt aatcccagag cgaaataata ttgcggcggt tccaaggatt ggtttccaac
    45241 tgtttgagaa gcttattgat aatgtcgtgt ttcttaacaa cggcaccata gcgctcacca
    45301 atggttcccg tgtctccaac ttcccagtca ttccagtagt gaacattgta cttgtcatta
    45361 agcacttcta agctatttga ctggtcttgg taaatccaga gaacttcttt gatggcggat
    45421 ttgattgcaa tgggacgcaa ggttgtgata ggaaattctc ctttagataa gtcgtactcg
    45481 gaaaaggcac cagttacata cttggaatta gcaacagtcc catccttgta cttaggacga
    45541 gcctgctctg agaaaacacc ttcctttaga atgcgttcaa tattctcttt aaaaatcgta
    45601 tctgcttttg tcatttcgtt tcacctcatt cattgtccta actagtatag cataaaaaat
    45661 aaaagaggaa cattactaac tctaggttag cattttcctc tctcattatc ttattgcaat
    45721 acaagtgatg ctgctccgat aactccagcg tcatttccta gagttgcaag agctaattta
    45781 gtagatgtgc gtacttgtgg gaaactattt tcatcgtaaa ctttttgaac accttgtaga
    45841 aggaattctc ccgcagctga cacaccacca ccgatgacga ttgttgatgg gtttaggatt
    45901 gaaccaatgt tagcacaagc gattcccaag taacgtgaga agttacggta aacaatcaaa
    45961 gcaaggtcgt ctccttcttt tgcgagatca aagacagtct tagcagttac ttcttctccg
    46021 ttatcaatca agcgtttcaa ggctgcatcg ccttcgtatt catcggcata gcgacgagtc
    46081 aagttgacaa tccctgttgc tgaagcaact gtctcaaggc agcctttttt accacaagta
    46141 catgagattg gttggtcaaa gtcaacagtg atatgaccaa gttcacctgc tgcaccagca
    46201 acaccatgaa gcaatttgcc ttctgcgaca ataccaccac caacaccagt accgagtgtc
    46261 ataaagacaa cgtctggttg gttatctcca gcacccatcc agcgctcacc aagagctgct
    46321 acgttggcat cattatcgat gaaaaatgga atgcccaaag ctttttcaat cttttgtttg
    46381 attggttgaa gggttttcca gttcaagttg taggcaccga taacagtccc tttttcacgg
    46441 tcaaccacac ctggtgatcc cattccaata ccttggaagt ccgctgctgc caatccaagc
    46501 aagtccaaac gatgttgaat agactcaatc atatcatcaa cgatatgact tccctcatcc
    46561 aaaatgttgg tcttgattga ccattttcct tggatttctc ctgctgttgt taagattgca
    46621 aatttgatag aagttccacc aaggtcaatc ccaataatct tttgactcat catattctcc
    46681 tttttcattg tgtagtaatt gaaaatgctt acagtactag tatatcaaaa tccattcact
    46741 tatgcaaagg tttgcgtaaa tgaattataa ggaatttttt cgcctaccag tatctgttaa
    46801 ccatctaaat gatcaatggc atattgagct gcatcatttg aaaatttatc aaaatcagaa
    46861 gttaattgtc tatacatacg tttttttgac atgtggaata acgaattata actttttgcc
    46921 tttcctaaag cagcagaata ttcactattg ctatcattac tagaagaagc tgtacttgct
    46981 tgaccttcct tccaaactcc gtcagcgcca acataataac gtccaccatc aacccattca
    47041 ttgacagcca ttttaccatc cgattttaga tagtaatttc cttgccatgt actgtaagca
    47101 taagaaccat ctgatgtcaa ataataccaa gcttgatagg tggcatcata aacccattca
    47161 cctttagcca ttttaccatc tgatttcaaa tagtagtttc cttgccatgc attgcgagca
    47221 tatgaaccat ctgatttcaa gtaataccat gcttggtaag aagaatcata aacccactca
    47281 ccttgtgcca ttttaccgtt tgatttaagg taataagctc cttgccatgt actgtaagca
    47341 taagaaccat ctgatgtcaa ataataccaa gcttgataag aagagtcata aatccattca
    47401 ctctgtgcca ttttaccatc agctttcagg taatagtttc cctgccatgc attttcacta
    47461 gatttccatt tccatcaaaa tagtaccaag aaccgtcctg cttaacccaa ccacttgctg
    47521 tggatgaagt tgtatcagtt tgagttgtag ccgcttgttt tgctttaaaa gcacccttag
    47581 gagcattttt caattcgcaa gccacaccat catgatcgcg gtctaacttg gcagaataac
    47641 caggttctcc ctcatgaaga tccgaatatc cattagccca agcttcctta caactcgaaa
    47701 aatgaatgtt ttcctctgct aacacaggtt gtgaaaacaa ggctaaaatt ggcaacgtca
    47761 ccagactcat ttttaaaaat agacgtttat tcatttcttt ctcccataat tatgatatcg
    47821 atttcaatat tattttatca aacttatttc agcaattcaa ggaaacttct ggtcttttct
    47881 acaaactcct ttggttttgc cttattcaag acatgagggc catctgggat aatctgaaat
    47941 tgggattctg atattagttt atgaagactt ctcatagaac taagattcgg tttatctttg
    48001 ataccacaaa ttagtaaggt tggataaggg caagttcctg ctatatccgt taaatcaagt
    48061 gtcttcaact cctcagaaac tccgaccata agagccttgt ctgctccctg tttttcaaat
    48121 actcttttgg gaagtagttt aaaaatcagc aactgaagat aaaataggat attccctgct
    48181 aatttaagcg ggcatcctga cagaatcaaa gctcgaagat ttggtaaatc gtaactggaa
    48241 agttctagtg ccagggcagc acctaaggac aatccaatca aaacaaaagg ttctgtctct
    48301 tgagctaggt gctgataaac tcgctcctta gcttgttgat agttactaac tccagaagga
    48361 aataactcga tagcctcaga aggataatct gtcagtagat tccgaacttc tttccaagac
    48421 tctgctgact gccctaaccc atgcaaaaat atcagtttca tctagttctc ctcaaggctt
    48481 agttcataca agcctctcac tgcattacag ccgtaaatag cttctgcttg ggctaaatct
    48541 gccaaggtca agactttctc ttctacctgt cctgtttcta gcaaatactg acggtaaatt
    48601 cctggcaaga ttccaagtcg gataggcggt gtgtagagtt ttccagcgat tttcagaacc
    48661 aaatttccta tagaggtttc aagcagtttt cctgacttat tgtggtaaat cttctcttgt
    48721 tctcctaggc tcaaatgcgg tcggtgagtg gttttaaagt aggtaaagga ttgattcaaa
    48781 gcagcttcct gaaggcagac ttgggcctga caaaagcttg tactgagagg ggttaatact
    48841 tgacgattga cttctatctc tccagatttg ctaaggctga ttcgcaagcg gtaatcttga
    48901 ttagcttcac aatcctgaca ctcttcctca atcttgtgtc ccaagtcttc tgcatcaaaa
    48961 ggaaaggcaa aataacgact agcttttctc agtctttcca gatgttgatc ttcaaacagc
    49021 aggttcttct ggctgatttc ccctgtcgta atcagttgga agcgggcttg tttacgataa
    49081 agaactgctg ccttttgatg aacctctcgg tattcagatt cccatgtgct atcccaagta
    49141 atccctccgc caactccata aatggcttga cctttgtgaa gttgaatggt acgaatggcc
    49201 acattaaaaa tccgtcgtcc atttggaagc aagagaccaa tcgttccaca gtagactcca
    49261 cgcggttgag gctccaagtc cttgataatc tccattgtcg caattttcgg tgcacccgtt
    49321 atggaaccac aaggaaagag tgagcggaag atttcaacaa ggtccacatc ctctcgcaac
    49381 tgactcttga tggtcgaagt catctgccaa acagttgaat actgctctac ctggcacaga
    49441 cgctccacgt gctcgctccc aacttcagaa atacggttca tatcattgcg caagaggtcc
    49501 acaatcatca tattttcaga gcgatttttg ggatcctgtt ccaaccaact ggcctgttca
    49561 agatcttctt ggtcagttac cccacgctga gtcgtcccct tcattggtcg tgttgtcaac
    49621 tcgcgatcat tttgctcaaa aaagagctct gggctcatgg aaatcactgc catctcgtca
    49681 tgttccacat aggcattgta gcccgcctcc tgctctacca ccatacgatt gtagatggca
    49741 aaaggattgg cacttaactt ttgcttgagt tggacggtgt agttgacctg ataggtgtct
    49801 ccctgcctca agtgatggtg tatctgggca atggcctttt catagtctgc tgcagacgtc
    49861 acttcctgcc aatttgaggg caaatcaata tcctcataag tcagaggaat aggggaggtc
    49921 tctaccctat catgaacagt aaagtaaagc aggtactctc ccagtagggg atccttgtga
    49981 actgctaatt tttcctcaaa agcaggggca gcctcgtagc tgacataccc caccacataa
    50041 taaccttgct cttggtagct ttccacttgt gccagcaaat ctgccacttc tgctacattt
    50101 ctcgttttta tctctttgat aggctgggta aaggtgtatc tctcccccaa aatcctaaaa
    50161 tcaatcactg tttttctatg cataccttaa gtatagcata aaataagaaa accctcatcc
    50221 gcaaagcaga tgagagattt caattattta aagattgaag ttttaaagct atttgtttgt
    50281 tgaagaagtt tcttataaac tttttctttt acttgcacaa gtttaccatt aactttatta
    50341 gtaaccatat cttcttcaag agctttggca aataatgatt ttaattcatc atagttatga
    50401 atggtctcac catcaatagt aaaaggagta aaaccagcgt tggctttttc taacaattct
    50461 ttataatatt ctttcttaaa atcagcaaac gattggaatc tgccgtcaga tattttttgt
    50521 ataatatatt gatctccaaa ttgtttccct tctttattag cttgagattt taatttatct
    50581 gaagcatatc ctaagaatcc tttatcatag ccataatatc cccagagtct aaatgcatta
    50641 ttcttaaatg taacagcacc gggtgcaccc tcacttgtgt tacctgcata gatactattc
    50701 atcattttaa ttcctacata ggcaatacct ggatcaaata cttctggctt atatatatta
    50761 ttattcatca tacgattagt catcagatta ttatcaacta agtcattaac actgtttaat
    50821 gttattcctt tccaatcatc agagctcata tttcgaacct tgtcatattg atcttttgac
    50881 cctacagtgc gttcaatagg atcaactttc ttaaaccaca gttgatttaa tttatcatca
    50941 tgtttactaa tgactgcatc accttcaaca taatcaagaa gagacaaggt atctatatag
    51001 cctttcatat aattatcaat gtcttctctt gttttaagag tcttcggatc ggtaatatac
    51061 cactgatttc catcatttgg acgatagaaa gtcatattaa ttcccaaagc accgtattca
    51121 tcaaaccatg tacttggtac tggtgtttgt aacattcctt gtgcataggc ttctgcatga
    51181 gtccctgagc gacgtccata tcctcctaaa tagattgcac gatcattaac atgagtagtt
    51241 tcatgtgtat aaacagagat tccaaactca tcaatcatac ttaatgcaat ataatttact
    51301 tctgttcgcg tatccaaagg attatcccaa ataactgcat aagcacctgt tccattgtta
    51361 ccataatact taccaatagg tccaaacaac tctctcaatg gggcatagtc ttctttatta
    51421 tttctcttac catacttatc aggccatcca ccaggtgctt gataaccttc ccaaagagga
    51481 gttactgtat ttttgactag catattctta accttatcta aagataatct ataccaaaaa
    51541 tcaaaataat ttcgataact gtccgctgct ttttcaatct gattttttat tccatcgaag
    51601 gagctatgcc ctaacttttc tgctgttcca acagccattg cactataatt cgagattaaa
    51661 tacacatgtg atttatttag atttaataat gggagtatca tcttccgatg agtagcagat
    51721 tgtaaattat cccaaacttt atatttcgcc gctttaattt catcgacttc cgaagcacgc
    51781 tccgctatat agacattccc ttctgtagct ttcttaaacc aatcataaat atttacatct
    51841 gcagtaaata gtcgacgatt ataatttaaa aagtttacca aattttctga taaggttgtc
    51901 ttagaaataa tctcgctgaa agcatcatat gtccgatgac cttttatatt atcttctctt
    51961 gaaccgattt caattaatct atctaataca cttacatttt taccatagaa atctggtttg
    52021 aataacatta attctttaat gttaacatca ccgaatttaa caccgtagta acggtttaag
    52081 tatgttaaac ctaataatag ggcagcttta tttttctcaa ctttatcaag aatcatttgt
    52141 tgagctgcag atgaattatt cagttgatga tcttcatttt caactaattt agttactaat
    52201 atgtttaaat tagcttttac atggtcaaaa ctttcttcta aataaaggtc tttaattgca
    52261 tttactctat tagaccctgt tctgccaagt ttttggtaaa ttggattaga ttgaagctca
    52321 atagggctta agatatttac gataccgtta attaaagcac tatgatcttt ttgaacgata
    52381 ttaggtgtat atttaatacc taagtcagtt atagtgtatt ctctaacatt acttagacct
    52441 tcatcactag aagataggtt gaagtagtct tttgttccat cagcataatg aacgataatt
    52501 ttgtttgcat cacctaaatc agttacaaag ttattattgt tcataggagt aaccgataga
    52561 atctctttag tatttaactt gttgttctta tctagtttat tagcttgatt aacgataaaa
    52621 tctttgttat agaatggttg tagtttttca atattcttat aagcaagttt atagtctgca
    52681 ttataatctt gaatagactc gtaagctgct tcacgactgc taacattatt caatttgttc
    52741 aattcataag gttcacttac gaatttagca gcagtaatat tgaaactagc aacttttgca
    52801 tcagcctcag atttagataa gtgttttaat ttatttttgt ttttattatc tttaccagtt
    52861 ccatcttcag aagagctata tccaataact ccaaataaat tagacacaaa aggatttgca
    52921 tctccatcat taacatcgtt tgaaccgaat atttcctgac ctttaataac tttcgcatat
    52981 gttacattat cttgaaccgc tccatatggc caagttttag aggttattcc accaacatat
    53041 ttagtatttt taacatcaag aatacctttt gctacagagt ttgtaagttt tccttttgtc
    53101 cctgatagcc agctatgagc tttatattga acgaaaggaa caagcatact tgcatttgcg
    53161 ttatttgctg taatagtagc atcaacgtag gctctattaa caaaccccat atagttagaa
    53221 ccggcaatac ctccaactgt tgaattatta ccagcagaat ttatactacc gataaatgcc
    53281 acattttcta aagtagcgtc ttcttttatg ttatttacga acccagcaac attatttcta
    53341 gctgttatgg ttccgattgc tttgatattt tctatacgtg tcgttccact gatttcattt
    53401 gctattgcag cgatattatc ttgattagat aaatcaatat caatattttc aaaatttata
    53461 tttttaacag ttccagcctt aatcttatcg aataaaggat gttccaaatt atggatagca
    53521 tagcgtttat caccatcact caatagttta ccagtaaact ctgaagtaat ataagatttc
    53581 cctttaggaa caacgttacg agcgctcatg ctttgaccca gtttaaattc accggcagga
    53641 tttgtctgaa tggcttggat caattcttca aagtcgtaga aaataccagc ctgactagct
    53701 ttgggttttt caatatagta ggtataagtt tcttcaaagc gattatcgac attacgttgg
    53761 accaagttat ccgctactgc tattaccttg tagacttgtt ttccatcaat tgttgactct
    53821 tcaatttttt gaaccgctag tagattggtc ttatggtcat tagaggtaac ttttaaataa
    53881 taatttgaca aatcagttgg cactgaagtc aatcgagttt catcagtttc aacttggttt
    53941 tcatatttga ttaaatccgt tcttataata tcttttattt caactttttt gagatcaatt
    54001 cttagcggtt cttctttcag aacttcttcc tcatccccct caccacggtc ataaaccatc
    54061 tttgtttcaa gtttataatc cttgtagtac tgcaaatctg tcagggtagt tgtcaagtct
    54121 tctggtgaaa cattcaaggt tttgacaatc tcatcacctt ttttcagagt tagggtaata
    54181 gatttaatgg ctgccttact tggattttct aaactatact taacatctga agtacgcttc
    54241 aaatccttag attcaatttc tgtgatggtc aacactggtt tttcaaagct cttggtacca
    54301 cgtttcaaaa ttttgtcttg aggttcctca aggatttcct ctgtaacttt tggagcgtct
    54361 tctgttttaa ctcccttaat ggtattaaag gtcttggtga tttttttctg gccttctttt
    54421 ccttcttgag ctacaacttc taagcctttt ttcagttggt catcttcttt aacaacttcc
    54481 ttaaatggaa tcttttcaag actttcttct ataagagttc cttcaattgg ttttgtacca
    54541 cggattacct gttgatttac aggctccttg gtcacttccg tactggttga aagaacttgg
    54601 tcagttttaa caccttctac tgttttatag gttgtttttg taacttgact tcctttttca
    54661 ccagttcgta ggacagtttc ttcgtccgta tacttggttg gatcctcagt cgtttcagtt
    54721 ttgtagtcta ggtctgtagt cgatgtttca acaagggttc cctcagttac tttgtactca
    54781 ggtaattgtt cttgagcaag agcctcaccc acgtgacctt tttcttgcgt acctttagct
    54841 gttttagtct cctcttttga ttctactggt tcttcaacct tgatttctgg ggcttctgct
    54901 ggctgttcat cttcttgttt cggtgtctct tccgctcccc tatcttcttt aggattttct
    54961 tgttgtgatg attcttttgg tgtacttggt tgctcagctt gtgtaggttg cacgggttgt
    55021 tctgggactt ttgcttgttc tactggtggt tcaacttttg attcctcagc tggtttgtct
    55081 gatggttgac tttctggctt aactgctact ttttcctctg gttttgactc aacttctcca
    55141 cctacttctt caactggagc tggttctgct gaatcttctt tcccctcttc tactttagga
    55201 agggtgtcgt cagtaggttt tacctccgat tttggttctt cctttggact ttcttctgtt
    55261 ttaggtgctt cttcttttgg agcttcctct gtctctacta cttggttttc tgtcctagct
    55321 tgctcctgat ttgttgttga ttgaggagtc tcaacttcga ctacagtcac ctctccaggt
    55381 tttgctgagg tttcttctaa aacagtgtcc aagccaagcg ttttgaggat gtcacctgat
    55441 agataaccaa catagcgata gccatccatt tcaacaacac cctctcgact agccagcgct
    55501 agggtcgcaa ctgggtctac agcccctgca ctaggaagaa ctaccaatcc catagctcca
    55561 actagaaaga cgctagcaat tttctttctc ttgtagatta aaagcaagct cccaacagtc
    55621 agcaaaccaa aagctgtcaa aacagatgct tctgtccctg tttgaggaaa ctgatctttt
    55681 tgatacacca aaccatatac aacttcattc ctgtcaggct ttcctgtctg aattaaatct
    55741 ttagcttctt gtgaaataat ctctttattt acatagtgat aggtggctgc gtccactaca
    55801 gaaggagcca tcaaaaggct tccaagaaat acagagccta caactccctt aatcttacga
    55861 attgaaaaac ggtctttttt aaacactttt atctccttta ttcattctca agactttcta
    55921 atagcatctt gcggatagtg cgcacgcgca cctccgatta attttggacg actagccagt
    55981 gccgttacat gggcatgacc aatctctctc aaaatagggc gaatcggaac ctgaacatgc
    56041 ttgacatgca tgccaattgc agtgtctccg atatccaatc cagcatgagc cttgataaat
    56101 tcaacctcaa ctggatcctg cataaactta aaggctgcca actgccccga acctcctgca
    56161 tgaagagtag gatggacact gacaatttcc agatcaaact gctctgccac ctgacgttca
    56221 acaacgagag cccgattgac atgctcacaa ccttgaactg ctaaatggat acctctacta
    56281 cctagaatac ccaagatagt ctccactatc agctcaccaa tctcttgact ggattctttc
    56341 ccaatctgac cacctagcac ctcactagaa gatagaccta aaacaaaaag gaccccctgc
    56401 ttcaaattgg tcttttctaa aacatcttcc actacctgac gtgtttctct ttgaatctgt
    56461 gtctcgttca tctctgttac ctctgttgtt actcttctat cataccgttt tttcttgttt
    56521 ttagcaagat agacaaccta gaaagcttgc ccaattacgc ataaaactcc cagaattgac
    56581 tgggagttag ctagtttcta ttctatttat atatatttca actttcgtcc ctttttgggg
    56641 tctagaatca atcttcatct ggtaattggc tccaaaatga agtttgagcc gttgatcgac
    56701 attttgaaga ccaactcccc cacgtttgag ttgactttga ctactatcac cagcatcttg
    56761 gaagccaacg ccatcatcct caatacggat gaccaatccc gaatcctgtt tctggacaga
    56821 aagtttaata tggccctgac cttccttttc cttaatgcca tggtaaagag cattttctac
    56881 aaggggttgt aggaccagct tgggtaagac taaattatca aaggcaacat tttcattaat
    56941 ttcgtattcc agcttatctc catagcgttg tttctggata aagagatact ggcggacatg
    57001 attgatttcg tcagagagac aaatcaagtc tttgccttga ttgagcgcca agcggaaata
    57061 ggttgccaag gacttggtca cctgcaccac tcgctgacta tcatgaaatt cagccatcca
    57121 gatgatggtg tccaaagtgt tatagaggaa atgtggatta atctggctcg aaagggcttg
    57181 aagttggtac tgacgggtcg tttcttcctg gctacgaata gctaccatca actgatcaat
    57241 ctgatccaac atggcattaa attggcgagt tacttctctc agttcatagg caccaacttc
    57301 cttggcacga agattttgag caccagaagc aatttccaac atggtttctc tcaaatcctt
    57361 caaaggagca atccagcgtt taagactgaa ccacactaag cagagacaaa caagaagaga
    57421 tgtgacactg gccccaagca aggtccacaa gagctgactc cgaacctggt ctaacttttc
    57481 caatgatgac acgccaagta ccgtccaatc agttcctgca atcttctctt gactgacgta
    57541 ggatttgtga ccaggagtat aaccctgacc tgtctcgatg tagggtttca tagcctccat
    57601 tttgctagac gaactataaa ctgtgtgttg aggatggtag acaaattcat ggttttcatt
    57661 gataatgaag gcaaagccct gctgccccaa ctggagttga ttgagatagg cttccagagt
    57721 ttcataagaa atatccaaac gaagcacacc aagattggct ccctttgcat caacaagttc
    57781 ttgagtgaca gaaatgaccc actgactatc tgatttacga gctggagtca aaacaggcat
    57841 agctccctga tgaatagcct tttggtacca atcctcagcc atcatatcag aggaagtttt
    57901 catctgcaca ctgtcatctg tagaaatgac ctgaccagat ttggtcacca gcacaacagt
    57961 tttcaagtcc ttatctgact tcaagatggt caaaaacaaa tctcggattc cctcgacctt
    58021 gtcttgactg ggattctcag cataggccag aacatccgtc tgctgggtca aaccagtcga
    58081 ggtggtttct agttttttga tataagactg aataaagtgg ctagtctggc tgatggtcgt
    58141 ttggctgttg ccctcaatgg tggcctcaat ggctgaagaa cttgattgat agtagaaagt
    58201 tccaaccaga gctaggagaa tgagaaagac cagaaagatg gaaataacca ttctaactaa
    58261 aagagaagaa cgcttcatcg gtcttctccc ttcttaaact gacgaggtgt cacacctgca
    58321 atctgcttaa aacgttgggt aaaatagttc atatcttcaa aaccaacctt ctctgcgatc
    58381 tcataaatct tcagatctgt agttaaaagc aagagcttgg cttgtttaac acgttctctc
    58441 accagataat cctgaaaagg caagcccaac tctttcttaa tcaaggaact cagataggtc
    58501 ggactaaaac ctaagtcact ggctaaagac tttaaactaa attggctatc agccagatga
    58561 gactggattt tctgggccat gtttccttca aacctattag tcaataaatc ttgtaactgc
    58621 tcttctttct cttccttgtc tagtttttgt ttgattttcc ccaacatttc ctcaatatcc
    58681 tgacgagaaa agggtttgag caggtagtcg tccacaccta gtttgacagc agacaaggca
    58741 taatcaaaat catcgtaacc tgttaaaaag accaaatgaa cctgaggata ggtttctcgt
    58801 accagactgg ccaactggat gccatttaga tgaggcatgt tgatatcggt taaaatgata
    58861 tctggcacct gcttttggat caattcccaa gcctgccttc cattttcagc ctgaccgatg
    58921 atttccatat cgtaggctgc tacattgacc agtttagtca aaccttgtct taccagatat
    58981 tcatcttcta cgattaagat tgtgtaggtc atgctctgct cctttaccac ttactagtat
    59041 cagtatagca aaattctcct ctaactgctt aggaaagacc tcttatactc aataaaaatc
    59101 aaaaagtaaa ctaggaagat agccacaggt ttctcaaagt atagctttga ggttgta
//
LOCUS       DAVBNZ010000007        49378 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000007 DAVBNZ010000000
VERSION     DAVBNZ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49378
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.007"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(93..551)
                     /locus_tag="VQ860_000405"
     CDS             complement(93..551)
                     /locus_tag="VQ860_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET3118897.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(548..988)
                     /locus_tag="VQ860_000406"
     CDS             complement(548..988)
                     /locus_tag="VQ860_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3118898.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1194..3143
                     /gene="mutL"
                     /locus_tag="VQ860_000407"
     CDS             1194..3143
                     /gene="mutL"
                     /locus_tag="VQ860_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET3118899.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVDQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3468..3935)
                     /locus_tag="VQ860_000408"
     CDS             complement(3468..3935)
                     /locus_tag="VQ860_000408"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET3118900.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(3936..5141)
                     /locus_tag="VQ860_000409"
     CDS             complement(3936..5141)
                     /locus_tag="VQ860_000409"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET3118901.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5161..5796)
                     /gene="ribE"
                     /locus_tag="VQ860_000410"
     CDS             complement(5161..5796)
                     /gene="ribE"
                     /locus_tag="VQ860_000410"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET3118902.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(5781..6881)
                     /gene="ribD"
                     /locus_tag="VQ860_000411"
     CDS             complement(5781..6881)
                     /gene="ribD"
                     /locus_tag="VQ860_000411"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET3118903.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7015..7129)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7286..7879
                     /gene="ruvA"
                     /locus_tag="VQ860_000412"
     CDS             7286..7879
                     /gene="ruvA"
                     /locus_tag="VQ860_000412"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET3118904.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            7889..8452
                     /locus_tag="VQ860_000413"
     CDS             7889..8452
                     /locus_tag="VQ860_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET3118905.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8449..9126
                     /locus_tag="VQ860_000414"
     CDS             8449..9126
                     /locus_tag="VQ860_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3118906.1"
                     /translation="MMSNKNKGILIFAILYTILFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9263..10294)
                     /locus_tag="VQ860_000415"
     CDS             complement(9263..10294)
                     /locus_tag="VQ860_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET3118907.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(10549..11232)
                     /locus_tag="VQ860_000416"
     CDS             complement(10549..11232)
                     /locus_tag="VQ860_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET3118908.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11244..12188)
                     /locus_tag="VQ860_000417"
     CDS             complement(11244..12188)
                     /locus_tag="VQ860_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3118909.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12320..15151
                     /gene="uvrA"
                     /locus_tag="VQ860_000418"
     CDS             12320..15151
                     /gene="uvrA"
                     /locus_tag="VQ860_000418"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET3118910.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDINQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            15144..16205
                     /locus_tag="VQ860_000419"
     CDS             15144..16205
                     /locus_tag="VQ860_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3118911.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            16337..16735
                     /gene="spx"
                     /locus_tag="VQ860_000420"
     CDS             16337..16735
                     /gene="spx"
                     /locus_tag="VQ860_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET3118912.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            16801..17370
                     /locus_tag="VQ860_000421"
     CDS             16801..17370
                     /locus_tag="VQ860_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3118913.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            17457..17723
                     /locus_tag="VQ860_000422"
     CDS             17457..17723
                     /locus_tag="VQ860_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET3118914.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            17727..18146
                     /gene="ruvX"
                     /locus_tag="VQ860_000423"
     CDS             17727..18146
                     /gene="ruvX"
                     /locus_tag="VQ860_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET3118915.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            18162..18467
                     /locus_tag="VQ860_000424"
     CDS             18162..18467
                     /locus_tag="VQ860_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET3118916.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            18773..20023
                     /locus_tag="VQ860_000425"
     CDS             18773..20023
                     /locus_tag="VQ860_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3118917.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            20020..20562
                     /locus_tag="VQ860_000426"
     CDS             20020..20562
                     /locus_tag="VQ860_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET3118918.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            20708..22240
                     /gene="cls"
                     /locus_tag="VQ860_000427"
     CDS             20708..22240
                     /gene="cls"
                     /locus_tag="VQ860_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET3118919.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            22318..22461
                     /locus_tag="VQ860_000428"
     CDS             22318..22461
                     /locus_tag="VQ860_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118920.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            22498..24036
                     /locus_tag="VQ860_000429"
     CDS             22498..24036
                     /locus_tag="VQ860_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3118921.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVGLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGEAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            24156..26363
                     /gene="nrdD"
                     /locus_tag="VQ860_000430"
     CDS             24156..26363
                     /gene="nrdD"
                     /locus_tag="VQ860_000430"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET3118922.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHHLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            26375..26515
                     /locus_tag="VQ860_000431"
     CDS             26375..26515
                     /locus_tag="VQ860_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118923.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            26559..27065
                     /locus_tag="VQ860_000432"
     CDS             26559..27065
                     /locus_tag="VQ860_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3118924.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            27058..27648
                     /gene="nrdG"
                     /locus_tag="VQ860_000433"
     CDS             27058..27648
                     /gene="nrdG"
                     /locus_tag="VQ860_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET3118925.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLGQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            27645..28262
                     /locus_tag="VQ860_000434"
     CDS             27645..28262
                     /locus_tag="VQ860_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET3118926.1"
                     /translation="MKKKGLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELSQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAYELESLQRDIFALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            28517..28825
                     /gene="rpsJ"
                     /locus_tag="VQ860_000435"
     CDS             28517..28825
                     /gene="rpsJ"
                     /locus_tag="VQ860_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET3118927.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            29042..29668
                     /gene="rplC"
                     /locus_tag="VQ860_000436"
     CDS             29042..29668
                     /gene="rplC"
                     /locus_tag="VQ860_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET3118928.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            29693..30316
                     /gene="rplD"
                     /locus_tag="VQ860_000437"
     CDS             29693..30316
                     /gene="rplD"
                     /locus_tag="VQ860_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET3118929.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            30316..30612
                     /locus_tag="VQ860_000438"
     CDS             30316..30612
                     /locus_tag="VQ860_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET3118930.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            30630..31463
                     /gene="rplB"
                     /locus_tag="VQ860_000439"
     CDS             30630..31463
                     /gene="rplB"
                     /locus_tag="VQ860_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET3118931.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            31567..31848
                     /gene="rpsS"
                     /locus_tag="VQ860_000440"
     CDS             31567..31848
                     /gene="rpsS"
                     /locus_tag="VQ860_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET3118932.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            31860..32204
                     /gene="rplV"
                     /locus_tag="VQ860_000441"
     CDS             31860..32204
                     /gene="rplV"
                     /locus_tag="VQ860_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET3118933.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            32217..32870
                     /gene="rpsC"
                     /locus_tag="VQ860_000442"
     CDS             32217..32870
                     /gene="rpsC"
                     /locus_tag="VQ860_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET3118934.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            32874..33287
                     /gene="rplP"
                     /locus_tag="VQ860_000443"
     CDS             32874..33287
                     /gene="rplP"
                     /locus_tag="VQ860_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET3118935.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            33297..33503
                     /locus_tag="VQ860_000444"
     CDS             33297..33503
                     /locus_tag="VQ860_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET3118936.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            33528..33788
                     /gene="rpsQ"
                     /locus_tag="VQ860_000445"
     CDS             33528..33788
                     /gene="rpsQ"
                     /locus_tag="VQ860_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET3118937.1"
                     /translation="MERNNRKVLVGRVVSDKMNKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            33814..34182
                     /gene="rplN"
                     /locus_tag="VQ860_000446"
     CDS             33814..34182
                     /gene="rplN"
                     /locus_tag="VQ860_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET3118938.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            34260..34565
                     /gene="rplX"
                     /locus_tag="VQ860_000447"
     CDS             34260..34565
                     /gene="rplX"
                     /locus_tag="VQ860_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET3118939.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            34589..35131
                     /gene="rplE"
                     /locus_tag="VQ860_000448"
     CDS             34589..35131
                     /gene="rplE"
                     /locus_tag="VQ860_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET3118940.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            35149..35418
                     /gene="rpsN"
                     /locus_tag="VQ860_000449"
     CDS             35149..35418
                     /gene="rpsN"
                     /locus_tag="VQ860_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET3118941.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            35703..36101
                     /gene="rpsH"
                     /locus_tag="VQ860_000450"
     CDS             35703..36101
                     /gene="rpsH"
                     /locus_tag="VQ860_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET3118942.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            36293..36829
                     /gene="rplF"
                     /locus_tag="VQ860_000451"
     CDS             36293..36829
                     /gene="rplF"
                     /locus_tag="VQ860_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET3118943.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            36913..37269
                     /gene="rplR"
                     /locus_tag="VQ860_000452"
     CDS             36913..37269
                     /gene="rplR"
                     /locus_tag="VQ860_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET3118944.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            37287..37781
                     /gene="rpsE"
                     /locus_tag="VQ860_000453"
     CDS             37287..37781
                     /gene="rpsE"
                     /locus_tag="VQ860_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET3118945.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            37753..37977
                     /gene="rpmD"
                     /locus_tag="VQ860_000454"
     CDS             37753..37977
                     /gene="rpmD"
                     /locus_tag="VQ860_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET3118946.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            38122..38562
                     /gene="rplO"
                     /locus_tag="VQ860_000455"
     CDS             38122..38562
                     /gene="rplO"
                     /locus_tag="VQ860_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET3118947.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            38575..39885
                     /gene="secY"
                     /locus_tag="VQ860_000456"
     CDS             38575..39885
                     /gene="secY"
                     /locus_tag="VQ860_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET3118948.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            40036..40674
                     /locus_tag="VQ860_000457"
     CDS             40036..40674
                     /locus_tag="VQ860_000457"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET3118949.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            40791..41009
                     /gene="infA"
                     /locus_tag="VQ860_000458"
     CDS             40791..41009
                     /gene="infA"
                     /locus_tag="VQ860_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET3118950.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            41034..41150
                     /gene="rpmJ"
                     /locus_tag="VQ860_000459"
     CDS             41034..41150
                     /gene="rpmJ"
                     /locus_tag="VQ860_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET3118951.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            41168..41533
                     /gene="rpsM"
                     /locus_tag="VQ860_000460"
     CDS             41168..41533
                     /gene="rpsM"
                     /locus_tag="VQ860_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET3118952.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            41551..41934
                     /gene="rpsK"
                     /locus_tag="VQ860_000461"
     CDS             41551..41934
                     /gene="rpsK"
                     /locus_tag="VQ860_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET3118953.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            41977..42912
                     /locus_tag="VQ860_000462"
     CDS             41977..42912
                     /locus_tag="VQ860_000462"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET3118954.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            42924..43310
                     /gene="rplQ"
                     /locus_tag="VQ860_000463"
     CDS             42924..43310
                     /gene="rplQ"
                     /locus_tag="VQ860_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET3118955.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            43575..43841
                     /locus_tag="VQ860_000464"
     CDS             43575..43841
                     /locus_tag="VQ860_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET3118956.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            43851..45188
                     /locus_tag="VQ860_000465"
     CDS             43851..45188
                     /locus_tag="VQ860_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET3118957.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            45432..46124
                     /locus_tag="VQ860_000466"
     CDS             45432..46124
                     /locus_tag="VQ860_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3118958.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(46227..47872)
                     /locus_tag="VQ860_000467"
                     /pseudo
     CDS             complement(46227..47872)
                     /locus_tag="VQ860_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(47862..48485)
                     /locus_tag="VQ860_000468"
     CDS             complement(47862..48485)
                     /locus_tag="VQ860_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118959.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAI
                     SDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEELQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            complement(48471..48593)
                     /locus_tag="VQ860_000469"
                     /pseudo
     CDS             complement(48471..48593)
                     /locus_tag="VQ860_000469"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(48570..48940)
                     /locus_tag="VQ860_000470"
                     /pseudo
     CDS             complement(48570..48940)
                     /locus_tag="VQ860_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(48953..49321)
                     /locus_tag="VQ860_000471"
     CDS             complement(48953..49321)
                     /locus_tag="VQ860_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3118960.1"
                     /translation="MTVGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKSK
                     NMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIK
                     NKSDIVKKYNEVFTDIQSKQ"
BASE COUNT        14872 a         9322 c        10871 g        14313 t
ORIGIN      
        1 tcctgttctt atttgatttc actatagtaa ggtgcagcag gataaagaaa aaccgagaag
       61 tttctttctc ggatttgctt attatgaggt tcctattttc tatgctccaa gagttgattg
      121 atgtgatcta cttttttagc ctctctttta tagagaatag cccagatgat gagatagaca
      181 atcgcaaact cgataatgag ctggaggtag aaaatccagt ggaaagggaa ccaaccagca
      241 agagttgcta gtgggacaaa gccagccagc ataaggaaga aatgagtcag agtggcacga
      301 agcatgctcc agtcacggct gaataagcgg ttgccaaagt tgaagagcat accgatggct
      361 gcccagataa gtgtgcagta gagcaagacc agggcaccgt gaacctgatg ctgatccatc
      421 acttggccga tgagagagta gggatttagt ggtgcgtagg tatttggtgc ataaatgagt
      481 gaaaagagga tggagaggat gaggccgata agaacaccgg cagctgcatc gtgaaatact
      541 tgttttttca tagttctaat ttctccttga tggtttttag ataacggcgt gaagagtagg
      601 tgaagctttc gtttttcaag aaaatttcta ccagaccgtt tggcgtgagc ttgaggtgag
      661 agatggaatc gatattgatg atttctgatt gggaaatttg gataaaattg gttggcaaga
      721 gtttaagaac ctgatagagt cgcaaatcaa tgctgtaggt ctgactcgcg gtttctgcta
      781 gaaccttccg attctcgata tagaagcgct gaatcttgcc aatctcaact agatagacct
      841 gatcatcgat tttccctttg attttttctc tttggtccag attttctgcg aactcgatga
      901 ctttctggac tttatctgtc ggctgaggtg cttggacaat cagcttttcc tcctcgtaag
      961 tctcactaat ctgtagttct actttcatag ttttctctcc ttttcagtta tacaaggttg
     1021 tgatcacttc ctgtatatcc ttattaaaca ctattttata gcccatggca aggaaccttg
     1081 tctatgtgga gggattgggc tcctatgtgg tggagctttt ctgttctttc tgaaatatgg
     1141 tataatagca ctaattaatt tctaggaaaa tagatacaga aaggggctga aagatgtctc
     1201 atattattga attgccagag atgctggcaa accaaatcgc agctggggag gtcattgaac
     1261 gtcctgccag tgtggttaaa gagttggtag aaaatgccat tgacgcgggc tctagtcaga
     1321 ttatcattga gattgaggaa gctggtctca agaaggttca aatcacggat aacggtcatg
     1381 gaattgccca cgatgaggtg gagttggccc tgcgtcgcca tgcgaccagt aagataaaaa
     1441 atcaagcaga tctctttcgg attcggacgc ttggttttcg tggtgaagcc ttgccttcta
     1501 ttgcgtctgt tagtgtcttg actctgttaa cggcggtgga tggtgctagt catggaacca
     1561 agttagtcgc gcgtgggggt gaagttgagg aagtcatccc agcgactagt cctgtgggaa
     1621 ccaaggtttg tgtggaggat ctctttttca acacgcctgc ccgtctcaag tatatgaaga
     1681 gccagcaagc ggagttgtct catatcattg atattgtcaa ccgtctgggc ttggcccatc
     1741 ctgagatttc ttttagcttg attagtgatg gcaaggaaat gacgcggaca gcagggactg
     1801 gtcaattgcg ccaagcaatc gcagggattt acggtttggt cagtgccaag aagatgattg
     1861 aaattgagaa ctctgaccta gatttcgaaa tttcaggttt tgtgtccttg cctgagttga
     1921 ctcgggctaa ccgcaattat atcagcctct tcatcaatgg tcgttatatc aagaacttcc
     1981 tgctcaatcg tgctattttg gatggtttcg gaagcaagct tatggttgga cgttttccac
     2041 tggctgtcat tcacatccat atcgaccctt atctagcgga tgtcaatgtg catccaacta
     2101 agcaagaggt gcggatttcc aaggaaaaag aactgatgac cctggtttca gaagctattg
     2161 caaatagtct caaggaacaa accttgattc cagatgcctt ggaaaatctt gccaaatcga
     2221 ccgtgcgcaa tcgtgagaag gtggatcaaa ctattctccc actcaaagaa aatacgctct
     2281 actatgagaa aactgagccg tcaagaccta gtcaaactga agtagctgat tatcaggtag
     2341 aattgactga tgaagggcag gatttgaccc tgtttgccaa ggaaaccttg gaccgattga
     2401 ccaagccagc aaaactgcat tttgcagaga gaaagcctgc taactacgac cagctagacc
     2461 atccagagtt agatcttgct agcatcgata aggcttatga caaactggag cgagaagaag
     2521 catccagctt cccagagttg gagtttttcg gacaaatgca cgggacttat ctctttgccc
     2581 aagggcgaga tggactttac atcatagatc agcacgctgc tcaggaacgg gtcaagtacg
     2641 aggagtaccg tgaaagcatt ggcaatgttg accagagcca gcagcaactc ctagtgccct
     2701 atatctttga atttcctgcg gatgatgccc tgcgtctcaa ggaaagaatg cctctcttag
     2761 aggaagtggg cgtctttcta gcagagtacg gagaaaatca atttattcta cgtgaacatc
     2821 ctatttggat ggcagaagaa gagattgaat caggcatcta tgagatgtgc gacatgctcc
     2881 ttttgaccaa ggaagtttct atcaagaaat accgagcaga gttggctatc atgatgtctt
     2941 gcaagcgatc tatcaaggcc aatcatcgta ttgatgatca ttcagctaga caactcctct
     3001 atcagctttc tcaatgtgac aatccctata actgtcctca cggacgtcct gttttggtgc
     3061 attttaccaa gtcggatatg gaaaagatgt tccgacgtat tcaggaaaat cataccagtc
     3121 tccgtgagtt ggggaaatat taaaagtata aaaaagtctg ggaaaaattt tcaaaatcag
     3181 aaaaacgcat aaaatcaggt gttcaaaaac cttgatttta tgcgttttat catggaaata
     3241 gttacttcat gttttcctaa ttcttttcga aactcttttt aaaccacgtc agttttatca
     3301 gtaatctcaa aacagtgttt tgagctaatt ttgccagttt tgtctgtaac atcgaagttg
     3361 tgtttgacca ctctgcgact ggtttcctag tttgctctat gattttcaca gagtattaaa
     3421 ttgcgatttt gccaagtttc tttattcgtc taaaagtaga gtctgttcta tgcgtctaat
     3481 gtacgaatta ggttgaccat ttcaatagct ccttgtgcac actcagaacc cttatttcct
     3541 gctttagtgc cagctcgttc tatggcttgt tcaattgtat ctgtcgttag cacaccaaac
     3601 ataacaggaa tttcgctatt taaactgatt tgggcgattc ccttagatac ctcgctacat
     3661 acataatcat aatgacttgt attccctcta atgacagctc ccaagcagat aattgcatca
     3721 tattttttac tttttgccat ttttgatgca atcagtggta tttcaaaagc tcctggaacc
     3781 caggctacct ctatatcttt ctcgtttaca ttctctcttt tgagattatc tagtgctcca
     3841 gataataatt ttgaagttat aaattcatta aatctcgcta caacaatacc tattttaata
     3901 ttgtttgcta ctaaattacc ttcataagtg ttcatttatt tttcctccat atttaaaatg
     3961 tgacccattc gatttttctt tgtttctaaa taaaaactat cgtaaggatt ggcttctatt
     4021 tcgattgata ttctactgga aatggtaatt ccatattttt ctaactgttc aaccttgtca
     4081 ggattatttg tcagtaaatg aagtgactga agtcccagat ctttaagcat ttgtgctcca
     4141 atatgatatt ctcttaaatc accttcaaag cctaatgcaa gattggcatc aagcgtatcc
     4201 atgccttgat cttgtaaatg ataggctttt aatttattga taagtccaat tcctcgtccc
     4261 tcctgtcgca agtaaagtaa gacacccgaa ccattctcaa caatcatttt catagcttta
     4321 tcgaattgct gtccacaatc gcaacgtaaa gagcctaaaa catctcctgt taaacattcg
     4381 gagtggaccc gacataatac attggcttca tcctctatgt ttcccataat aagagcaaga
     4441 tgatgttccc catttagttt atctatatag ctaattgctt tgaaattacc gtatctagta
     4501 ggcatattga cagttgaaac tcgttctacc agctgatcat atacttttct atattcttgt
     4561 aattctttga tggtaattag tggaatgttg tgtttcttcg agaactgaat taaatcatct
     4621 gttctcatca ttttgccatc atgattcatt atttcacaac ataggccaca ctcttttagt
     4681 ccagctaatt ttaataaatc aacagttgct tctgtgtgtc catttctttc tagaacacca
     4741 cctttttttg caattaaagg aaacatgtgt cctggcctgc gaaaatcaga gggtgttata
     4801 tcttcagcta cacacatacg tgcggtcagt cctctttcct cggcagaaat acctgtggtc
     4861 gtttctttat aatcaattga aactgtaaaa gcagtcttat gattatctgt attgttttca
     4921 accataggtg aaagcattaa ttgattagct aaactttcgc tcataggcat acaaattaat
     4981 cctttggcat aagtagccat aaaattaaca ttttctgttg tagctgcttg tgcagaacaa
     5041 attaagtctc cttcattttc tctatccttg tcgtctataa caagaacaag tcgtcccttc
     5101 tgcaatgctt ctaatgcttc ttgtattttt cgatattcca ttgactgatt atcctttctg
     5161 ctaaaatcca ttttgatata atagttcctt agatatttct gattttggag agttatccat
     5221 cagtttttgc acatatttac ctaagatatc attttcaaga tttactgtac tcccgacttg
     5281 tttactctta agaatggttt gttccaaggt atgagggata acagatactg aaaagtttac
     5341 tttggagact ttagcgacag tcagactaat gccgtcaatt gtaatagatc ctttttcaac
     5401 tattaaatct aaaatttctt tttgtgtgtt gatttgatac catacagcat tatcatcttt
     5461 ttttattgac gagatttttc ctgtaccatc aatgtgtcct gtaacgacgt gacccccaag
     5521 tcgaccgttg acagataagg ctctttctag attcacctca cttccatgtt ttaatagagt
     5581 aagagctgtt cgactccatg tttcattcat tacatcaact gtaaaggatt gatgattgaa
     5641 atgagtaact gtaagacaga taccatttac tgctatacta tcgcctaaat ggatatccgt
     5701 taatattttt gaggctttaa ttgatagttt acaattacga gagtctttct gtattctttc
     5761 aacttttccg atttcttcaa ttattcctgt gaacatggat aaatcacttc actttctatg
     5821 agatagtcat ttcctatttg agaaaatgca taaggtttca atctaatagc gtcatttggc
     5881 aaagaaatgc cttcacctcc gacaggaaac ttggcactgc ctccaaaaat ttttggtgca
     5941 atatatattt tcagctcatc aacaatttgt tgttccaaag cactccaatt cattagactg
     6001 cccccttcta gaactaggct atcaatctgc atgtttccta gatgttgcat taaactcgat
     6061 aagtctatat gattgccttt tttctttatg gaaagtattt cacagccatg attttgatat
     6121 agcttcattt tatttttgtc ttcagaggaa gtggcaatgt aagttttaat atcatttgct
     6181 gtttttacga ttttagaggt aagaggagtt cgtaaatgtg tatcgcatat gatacggata
     6241 ggatttttcc cttcctccaa tctacatgtc agcaaaggat cgtcttgaat aacagtattg
     6301 actcccacca taattgcact aacatggtgt cgtaactgat gcacatgctt tcttgcttct
     6361 tcttcagtaa tccatttgga ttgatttgtt ttagtggcta tttttccatc cattgacatt
     6421 gcatatttca taaaaacata gggtacatgc tgggtaatat actttctaaa actttttatt
     6481 aagttaagac actcattttc taaaattcca acagtaactt gaagattatt ttcctcaagt
     6541 atctttactc cttttccaga tacaatagga ttacagtcta ggcttccaat gactactctt
     6601 gtaataccac tatcgattat agcatctata cagggaggtg ttttcccgaa gtgacaacag
     6661 ggttcaagtg ttacataaag cgtcgctccg acaggggatt ttctacagtt tttaagagca
     6721 tttctctcag catgtgggcc accaaaaaac tcatgataac cttgtccgat aatgtgatta
     6781 tcttttacaa taattgcgcc aaccatagga ttgggattga cgtaaccagc ccctttttgt
     6841 gccagtttta ttgctaattt catatatttt gaatcgctca tctcactacc tccaaaaaaa
     6901 tataccttga ataggggact actcaaggca tacaaaagaa aacttatgcg attaacaaaa
     6961 atgctctgaa atgacaagta atcatttcag agcacgcaaa aagcacaaat atacttttat
     7021 cttctttcat ccagactata ctgtcggctt tggaatttca ccaaatcatg cctttcggct
     7081 cgtgggctat accaccggta gggaattgca ccctgccctg aagatagtta ttcaattaca
     7141 gatgattata gtacttaatt ttgaatatgt caacagataa atacagattg tttttgatat
     7201 actgtatttg tgataatcga ttctcgctcc tcggataaag aaaatatgat atactagata
     7261 aacgaaataa gagagaagga acactatgta cgcatattta aaaggaatca ttaccaaaat
     7321 tactgccaaa tacattgttc ttgaaaccaa tggtattggt tatatcctgc atgtggccaa
     7381 tccttatgcc tattcaggtc aggttaatca ggaggatcag atttatgtgc atcaggttgt
     7441 gcgtgaggac gcccatttgc tttatggatt tcgctcagag gatgagaaaa agctctttct
     7501 tagtctgatt tcggtctctg ggattggtcc tgtatcagct cttgctatta tcgctgctga
     7561 tgacaatgct ggcttggttc aagccattga aaccaagaac atcacctact tgaccaagtt
     7621 ccctaaaatt ggcaagaaaa cagcccagca gatggtgctg gacttggaag gcaaggtagt
     7681 agttgcagga gatgaccttc ctgccaaggt cgcagtacaa gcaagtgctg aaaaccaaga
     7741 attggaagaa gctatggaag ccatgttggc tctgggctac aaggcaacag agctcaagaa
     7801 aatcaagaaa ttctttgaag gaacgacaga tacagctgag aactatatca agtcggccct
     7861 taaaatgttg gtcaaatagg agcagagaat gacaaaacgt tgttcgtggg tcaagatgac
     7921 caacccgctc tacatcgcct atcatgatga ggagtggggt cagcccctcc atgatgacca
     7981 agcattgttt gagttgttgt gtatggaaac ctatcaggca ggcctgtctt gggaaacggt
     8041 actcaacaaa cgccaagctt tccgagaagc ctttcatagc tatcaaattc actcagtcgc
     8101 agagatgact gacactgaat tggaagccat gctggagaat ccagctatca ttcgaaatag
     8161 agccaagatt tttgctacac gcgctaacgc ccaagccttt ctacagttac aggcagagta
     8221 cggctctttt gatgcctatc tttggtcttt tgttgagggg aaaactgtcg ttaacgatgt
     8281 tcctgattat cgccaagccc cagctaaaac acccttatct gagaaattag ccaaagatct
     8341 caaaaaacga ggcttcaagt tcacaggccc agtcgccgta ttgtcttttc tacaggctgc
     8401 agggctagtt gatgaccacg agaatgattg tgagtggaaa ggtcttaaat gatgtctaac
     8461 aaaaataagg gaattctgat ttttgcgatt ctctatacaa tcctctttgt gtttgatggc
     8521 gttaaattgc tggcttcttt aatgccatct gtcattgcaa attatcttgt ttatgtagtt
     8581 ttagctttat atggctcctt cttgttcaag gatagattga tccaacaatg gaaggagatt
     8641 agaaagacta aaagaaaatt cttctttggc gtcttaacag gatggctctt tctcattctg
     8701 atgactgttg tctttgaatt tgtatcagag atgttgaagc agtttgtggg attagatgga
     8761 caaggtctaa atcagtctaa tattcaaagt acctttcaag aacaaccact actgatagct
     8821 gtttttgctt gtgtcattgg acctctggta gaagaattat ttttccgtca ggtcttattg
     8881 cattacttgc aggaacggtt gccaggttta ctaagcatta ttctggtagg acttgttttt
     8941 gctctgactc atatgcacag tttggctcta tcagagtgga ttggtgcagt tggttactta
     9001 ggtggaggcc ttgccttttc tattatttat gtgaaagaaa aagagaatat ctactatccc
     9061 ctacttgttc acatgttaag caacagcctc tccttaatca ttttagctat cagtatagta
     9121 aaatgaaatg agaacaggac aaatcgattt ctaacaatgt tttagaagta gaggtgtact
     9181 attctagttt caatatactg taatatgtga tgaaaatgcc agtaatgata ccgagaaaaa
     9241 agctgagaaa cttttcccag ctttatttgt tatagtcaaa gagaatgact tgttcctgtg
     9301 catctacatg agcatggacc ccaaagggta caattgctct tggagttgcg tggccgacat
     9361 tcagattata gacaatcggg atattgctgt caatgatatc caatagtgcc tctttatagt
     9421 cgtcatggaa agtttcatcc ataggttttc cgaccaagag tccattgatg accgcgaata
     9481 tgccagtgtc ctttaaagtt agcaacattt ttttgaagtc ttctggctta ggcttttctt
     9541 cgcttgtttc gagcaagagg attttccctt cccagtctga caagtcaggg aaaagtttgt
     9601 atttttggca gagttccgtg ctatctgcgt atcgagagtt gtcaaagata tcgtagaggg
     9661 attcgaggca accaccgagg attttcccct cgaactgagc acttccttgc aacaagtcaa
     9721 aacctgtatt tgtatgactg acacgaggtg ttcccagggc cgtgggacta aaatcagttc
     9781 gttcctcata ccaaacgtca ctagggcgga tttctgaaat tcttcccgtc ttaatcaatt
     9841 ctttaaagta gtgaaggcta taggctagca tttctttgtc taattcacaa atgtctgcta
     9901 aaaaggattg accataaaaa gtcttgattc ctaatttatg caacatgagg tggttcatgg
     9961 ttgtatccga gaagccaaga aaaatttttt gcttgataac cttttggagt tggtcatttt
    10021 caaaaagata aggtagcaag cgataggtat cgtctccacc gatggcacat aggatcatgt
    10081 cgatgctatc atcagaaaag gcatgaatca aatcctctgc acgagcttca ggatggtcct
    10141 tgataaagtc taatcctttt aacgaatggg acaaaaagat gggattgagt cccagatcct
    10201 tgagacgttg gatacccaag tccacttcgt gtttgacaaa atcctctccg ataatgccac
    10261 tagataaact aacaatacca atagtagaaa ccatatctca tcctcctaga aatagattga
    10321 gcctatttta tcacaaaata taagagaaag ctatgtggga tttcagaaga atacttttaa
    10381 tactcttcga aaatctcttc aaaccacgtc agttttatct gcaacctcaa agctgtgctt
    10441 tgagcaacct gcagctagct tcctagtttg ctctttgatt ttcattgaat ataactcaaa
    10501 aaagtaagtg aaaaagcaac cgcacctgca gttgctttta tcgttttctt attcttgata
    10561 gcgtgttggt cctgcacttg cactacggat attcaagcgt ttcttgagat agaagcgaag
    10621 ggctaggagg gctgctccaa taatagctag tggcaatgga tccagtactg ggttaaggct
    10681 agctggtagg aagcttgttg caaagaagac aagcaaccaa aggaacatag aagctaggat
    10741 aactagtaca gatttccaga aaggtggacg ttgactgcga tccatatctg atccatagta
    10801 ttggtaaaca aagtagtaca tcaagtagaa ggcaaatcca ccaaccagtc caactaatag
    10861 aagagtaatc aatccatagc cgaaagcttg gtctgccgca aagaaggttg tgagggcgct
    10921 gacaagggca aagaggctag tgatgaaaag agctgagtcc ataatcatca gttttgggtc
    10981 atcattttct tttggatgct ctttttcgta ctgctctttg acagtgaagc tatgagccca
    11041 atgagttggt gcgccgtata gggaacgggc agttgtacct ttagattgct cctcaaggat
    11101 ttggggaatg acttcctcaa aaatagtctg gatttcagcg tctgttttcc catctttgat
    11161 gaattgttgg gtagcaatgt ggacaaactc ttggtttttc ttagttaatt tttgtagatc
    11221 aatttgagac ataggaactc ctcttagaac cattttttat ggatgagata gagagtgagc
    11281 gagacactca tagcaaaggc gataaagacg attaaccaga aggcatttgg ctctccgttt
    11341 agggggattt cattatcctt aaagttcatc ccgtaggcag aaaagaccat ggttgggatg
    11401 gacatgacga tggtcacaag ggccaaggtt ttcatgatgt tgttctggtt gttagaaatg
    11461 atagaggcaa aggtctctgt catagaatgc aagacgtttc cataaatatc tgccatctcg
    11521 atggcctgtt gggtttcaat cagggtgtct tcaagcaggt cttcgtcctc aaggtatttc
    11581 ttgatattgc tggttgaact ggtcaatttc ttaatcacgc gctcatttgt tttgagggag
    11641 gccttgaaat agacgatagt tttttccaat tccatgagct caatcaattc ttcattacga
    11701 gttgattgat gcagttgact ttcgatttgt tcactcttgc ggtcgattga acgaagggct
    11761 gttaggtaaa gctctgcatt gcgataaaga atttgaaaga taaaacgtga acgcatgaag
    11821 gtatagaaat tacgcaatcg acggttgata aagacatcaa ggacaggtag tggttccaaa
    11881 cacgtagtga taatggtttc ctcagtgatg ataataccaa gcgggatggt tacgtagtag
    11941 gtgcggttat ttctttcctc cgtgaccggc acgtctacga taatcagggt atactcgtct
    12001 tcaatggtaa tacgagacat ttcttccgca tcgagcggtg ctcgaaggtc ggcaatatca
    12061 atatcgaagg tgttggcgat ttcgagtgat tcattttgag tcggattgac gagattgatc
    12121 caagtacccg gttcaagcgt atcgatctct ttaaattcag ttgttgtaga gagaaaaact
    12181 tgtttcatat cccttatcct ttctcatttt tcagattttt tcacactgta ctattatact
    12241 acaaaatcgg ccttttgggt aatagaatct cacttttttt ggtataatgg taagcaataa
    12301 tggactagaa agaacaaaga tgcaagataa aattgtcatt catggggcgc gtgcccataa
    12361 tttaaaaaat attgatgtgg agattccgcg agacaagttg gttgtcgtga ctggcttgtc
    12421 aggttcaggg aagtccagtc tggcttttga tactctctat gcggagggac aacgtcgcta
    12481 tgtagagagt ttgtccgcct acgctcgtca gttcttggga aatatggaaa aaccagatgt
    12541 agatgccatt gatggtctca gcccagctat ttccatcgac cagaaaacga ctagtaaaaa
    12601 tcctcgctcg acggtgggaa cgacgactga aatcaatgac tatctgcgtc tcctctacgc
    12661 acgtgtgggg acgccttact gtatcaacgg acatggagct atcaatgctt cttctgtgga
    12721 gcaaatcgtt gataaggttt tggagttacc tgaacgccag cgcttgcaga tcttggctcc
    12781 tgtcatccgc aagaaaaaag gccaacataa gagtgttatc gagaaggttc agaaagacgg
    12841 gtatgttcgt gtccgtgtgg atggggaagt ctatgatgtg accgaagtgc cagagttgtc
    12901 taagagcaag caacacaata tcgatgtcgt ggttgaccgt attgttatca aggagggcat
    12961 tcgtagtcgt ctctttgatt ccattgaggc tgcccttcgt attgcagaag gttatgtcat
    13021 tatcgacacc atggacgact cggagttgct cttctctgag cattatgcct gtccagtttg
    13081 tggatttact gtcccagagt tagaacctcg tctcttctct ttcaatgctc cctttggctc
    13141 ttgtagtgag tgtgacggct tggggattaa gctggaggtg gatactgatt tggtagtgcc
    13201 agatgccagc aaaaccttac atgagggagc gctggcacct tggaatccta tctcatccaa
    13261 ctactatcca aacatgttag agcaggccat gaaagtcttt ggagtggcta tggataagcc
    13321 ttttgaggac ctgtcagaag aagataagaa cttgattctc tacggctcag atggtaagga
    13381 attccatttc cattatgaaa atgaatttgg tggtgtgcgc gatatcgaca ttccgtttga
    13441 gggagttatc aataatatca aacgtcgtta ccatgaaacc aatagcgatt acactcgcac
    13501 tcagatgcgt ctctacatga atgagctgac ctgcggaacc tgtcaaggct atcgtctcaa
    13561 tgaccaggcc ttgtctgtcc gtgtgggcgg ccagcaaggg ccacatattg gagaaatctc
    13621 agacctgtct atcgctgacc acttggactt ggtgagccag ttaactttgt ctgaaaatga
    13681 agccatcatt gctcgtccca ttctcaagga aatcaaggat cgtttgacct tccttaataa
    13741 tgtgggtctt aactatctaa ccctgtcacg ttcagcagga accctttcag gtggggaaag
    13801 tcagcgcatt cgtttggcaa cccagattgg ttccaaccta tcaggtgtcc tctatatcct
    13861 agacgagccg tcaatcggtc ttcaccagag ggacaatgac cgcctgattg ccagtctgaa
    13921 aaagatgcgt gacttgggca atactcttat cgtggtggaa cacgacgaag ataccatgcg
    13981 tgaagctgat tatctgattg acgttggtcc tggtgccggt gtttttggtg gtgagattgt
    14041 tgcagcaggt acacctaagc aagtggctcg caacagcaag tctatcacag gtcagtactt
    14101 gtcaggcaaa cgtgtcatcc cagtaccaga agagcgccgt gtcggaaatg gtcgttttat
    14161 tgaagtgaca ggagcgcgtg agaacaactt gcaaaatgtc acggctcgct ttccactagg
    14221 aaaatttatc gcagtgacag gtgtgtcggg ttcagggaaa tcgactctaa tcaacagcat
    14281 tctcaaaaaa gccattgccc agaagctcaa ccgtaattca gacaaacctg gtaagtttaa
    14341 gactattaca gggattgagc atgtcgaccg tttgattgat attaaccaga gccctatcgg
    14401 acggacgccg aggtctaacc cagctaccta tacaggagtt tttgacgata tacgtgacct
    14461 ttttgctcag acaaatgaag ccaagattcg aggctacaag aaggggcgct tcagtttcaa
    14521 cgtcaaggga ggtcgctgtg aagcttgctc aggtgacggg attatcaaga ttgagatgca
    14581 cttcttgcca gatgtttatg tggcttgtga agtttgccac ggaacccgct ataacagtga
    14641 aaccctagaa gttcactaca aggaaaagaa tatttcgcag gtcttggata tgacggtcaa
    14701 cgatgcggta gaatttttcc aacacattcc gaaaattcaa cgcaaactcc agaccatcaa
    14761 ggatgtaggt ctaggctatg tgaccttggg acagccagct accacccttt ctgggggaga
    14821 agcccaacgt atgaagttag ctagcgaact ccacaaacgc tcgacaggaa aatctttcta
    14881 cattctggat gagccgacga cagggcttca tacagaggac attgctcgcc tgctcaaggt
    14941 tttagctcgc tttgtagacg ccggcaatac agtcctcgtc atcgagcaca atctggatgt
    15001 tatcaagacg gcagaccata tcattgactt gggacctgag ggcggtgtcg gtggtggaac
    15061 catcatcgta acaggaactc cagaagaagt agctgccaac gaagccagct atacaggaca
    15121 ctatttgaaa ggaaagttac atcatgaata aacgcgtaca agcatttcta gctaaaatgc
    15181 aagaaaaaga actagatggt atcatcatca acaatcttaa aaacgtctat tatttgactg
    15241 gtttttgggg ctcaaacgga acagtcttta tcagccgtga ccgtcaggtc ttagtgacag
    15301 actctcgcta tatcatcgca gctaagcaag aaaccagtgg ttttgagatt gtggctgatc
    15361 gtgatgaatt ggctgtcatt gcaggaattg ttaaggacat gaacttgact cgtatcggtt
    15421 ttgaagatga gatttcagtg tcttattacc accgtatgca ggcagctttt gcaggtttga
    15481 acttgcttcc acaaactcag tttgtggaag gtcttcgtat gattaaggat gaggcagaga
    15541 ttgcagcgat tcgcaaggct tgttctatct cagaccaagc tttccgcgat gcgcttgact
    15601 ttatcaaacc aggaaaaact gaaattgaga ttgccaactt ccttgatttc cgcatgcgtg
    15661 agttgggagc atctggctta tcttttgata cgatcctagc tagcggtatc aattcttcta
    15721 aaccccatgc ccatccaatg cacaaaccag tggagttggg agaagccatc accatggact
    15781 tcggctgtct ctatgaccac tatgtcagtg atatgacccg gactatctat ctagggcatg
    15841 ttagcgatga gcaggcagag atttacaata cggttctaaa agctaaccaa gccttgattg
    15901 accaagctaa ggcaggctta ggtttccgtg actttgacaa aatccctcgt gatattatca
    15961 ttgaggcagg ttatggtgac tactttactc acggcattgg ccacggtatt ggtctggata
    16021 tccatgagga accctacttt agtcagactt ctacagaaac tattaagaca ggtatggcct
    16081 tgaccgatga accaggtatc tatatcgaag gcaaatatgg cgttcgtatc gaggatgata
    16141 tcctgattac agagacaggt tgtgaattat tgaccctagc tccaaaagag ttgatagtca
    16201 tttagttgtt tgtcaagaaa aaagtacgaa aatgacgaaa aaagtcaaaa aaaattaaaa
    16261 ataggtcgca agtcggatgt tttttatggt ataatagact aaactgatag taacatgtag
    16321 cgaaaggggt aggtacatga ttaaaattta tacagtctca agttgtacta gctgtaaaaa
    16381 agcaaaaacc tggctcaatg cccaccagtt aagttataaa gaacaaaacc ttggtaaaga
    16441 aggaattacg agagaagaat tactggatat tctaaccaaa acagataacg gaatagccag
    16501 catcgtttcg tctaaaaatc gctatgccaa agcccttgga gtggatattg aagatttgag
    16561 tgtcaatgaa gttctcaatc tgattatgga aacaccgaga attttaaaga gcccaatcct
    16621 tgtagatgaa aaacgcctgc aagttggcta caaggaagac gatattcgtg ccttcctacc
    16681 acgatctgtc cgtaatgtag aaaatgcaga agcacgtttg cgtgcagctc tataaacatc
    16741 aaggctggga gcacttccca gtcttattct attttaattt caaaaagaaa gaagaaagaa
    16801 atgaaaaaaa tagttcttgt tagtctagct ttcctttttg tcctggttgg ttgcggacag
    16861 aaaaaagaaa ctggaccagc tacaaaaaca gaaaaagata cgcttcagtc ggcattgcca
    16921 gttattgaaa atgctgagaa gaatacagtt gtaactaaga ctttggtctt gcccaagtca
    16981 gatgatggta gccagcagac acaaacaatt acttacaaag acaagacttt tttgagtcta
    17041 gctatccaac aaaaacgtcc agtctctgat gagttgaaga cttatattga ccaacatgga
    17101 gtggaggaaa ctcaaaaagc tcttcttgaa gcggaggaga aggataagtc tatcattgaa
    17161 gctcgtaaat tggcaggttt caaacttgaa acaaaactat tgagcgcaac ggaacttcaa
    17221 acaacgacta gttttgattt tcaagttctg gatgtcaaga aggcttccca gttggaacat
    17281 ctgaagaata ttggtttgga aaatcttttg aaaaatgaac caagcaaata tatttcagat
    17341 agattggcaa atggcgcgac agaacaatag aaaatccaaa taaatagact gcctgaattg
    17401 tagaaggtaa ggaattatgc tataatggta ctattctaag gaaagagggt gttagaatgg
    17461 gatttactga agaaacagta cgttttaaat tggacgattc caataaaaaa gaaattagcg
    17521 aaactttgac agatgtttat gcttcgttga acgataaggg ttacaaccca attaaccaaa
    17581 tcgtaggtta cgtattgagt ggagaccctg cctacgttcc tcgttataat aatgcacgaa
    17641 atcaaatccg taagtatgag cgtgatgaaa tcgttgagga attggttcgc tactacctca
    17701 aaggacaagg agtcgatcta taacctatga gaattatggg attggacgtc ggttcaaaaa
    17761 cggtaggggt ggcgattagc gatccgcttg gttttacagc tcaagggctt gaaatcatcc
    17821 agataaatga agaacaaggc caatttggtt ttgaccgcgt taaggaattg gttgatactt
    17881 acaaggtgga acgatttgta gtgggcttgc ctaaaaacat gaacaataca agtggaccgc
    17941 gcgtagaagc tagtcaagcc tacggagcaa agctagaaga gttttttggt ttaccagtag
    18001 actatcagga tgaacgcttg acaacagtgg ctgctgagcg catgttgatt gaacaagcag
    18061 atatcagtcg caataagcgc aagaaagtca ttgataagtt agcagctcag ctgattttac
    18121 aaaattattt agatagaaaa ttttaatata aaggagaggc tatgtcacac gatcataacc
    18181 acgaccacga agaacgtgaa ctaatcacac tagtagatga gcaaggaaat gaaaccttgt
    18241 ttgaaatcct tttgacaatt gatggaaaag aagaatttgg taaaaactat gttcttctag
    18301 taccagttaa cgcagaagaa gacgaagacg gacaagttga aatccaagct tactcattca
    18361 ttgaaaatga agatggaaca gaaggcgaat tgcaaccaat cccagaagac tcagaagacg
    18421 aatggaacat gattgaagaa gtcttcaaca gctttatgga ggagtaaaaa cgtccggggg
    18481 acgtttttag ccctgcgcta gaaattagaa acgcaggtag tctgggagac tgtatcagcc
    18541 caactccaga aatggggaag agttggaacg tccagtgaac atttttaccc caactcttag
    18601 aaattgagaa gagttggaac atctagtgga tgtttttagc ccatattcac attcatagta
    18661 gctagttatt agctaaccag gtaagaggtc gggacgaaaa tcctggcctt gtttttatta
    18721 gtaaccatac tttaatgcga taattgattg gacttttgtc aaggagatgt gtatgtttga
    18781 agtagaagaa tggctccata gtcggattgg tttgaatttt cgatcaggtt tgggccgaat
    18841 gcagcaagcg gtggatttgt taggaaatcc tgagcagtct taccctatta tccacgtaac
    18901 agggactaat gggaaaggat ctaccattgc ttttatgagg gaattattta tggggcatgg
    18961 caaaaaagtt gcgaccttta cctcccctca tatcgtatcc atcaatgacc gaatctgcat
    19021 taatgggcaa cctatagcag acgcagactt tatccgtttg gctgatcagg taaaggagat
    19081 ggagaaaacg cttctgcaaa ctcctgacca gttgtccttt tttgaattgc tgaccttggt
    19141 tgcttttctt tattttaggg agcaggaggt ggatttggtt ttattagaag tgggaattgg
    19201 tggcttactt gacacgacca atgtggtaac tggagagctt gctgtcatca cctccattgg
    19261 gcttgaccat caagaaacct tgggtgatag tctagaagca attgcagagc agaaagctgg
    19321 tattttcaag gctggtaaaa aggcagtgat tgcgaaattg cctccagaag ctagacttgt
    19381 ctgtcagaaa aaagccgaat ctttagctgt tgacctttat caggcaggtc aagatttttc
    19441 agtgctgaat ggtgattttt caagctcttt actaaatctt tcacagctga acataggctt
    19501 agaaggagcc tatcagcagg agaatgcggc cttggcgttg caaacttttc ttctttttat
    19561 gggagaaaga aaggaagcta ttgatgaaca ggctgtaaga aaggccttgg aacagaccca
    19621 ttgggctggt cgcttggagc gtattcgccc acagatttac ttggatggtg ctcataacct
    19681 ccctgccttg actcgcttgg ttgagtttat caaagaaaaa gagcaggaag gctatcgacc
    19741 tcaaatcctc tttggatcct tgaaacgtaa ggattatcaa gggatgttgg gttatctgac
    19801 tgaaaattta cctcaagtgg aactcaaaat gaccggcttt gactatcaag ggtctttgga
    19861 cgagacagat gtaacaggtt accatgtaat tccctcttac cgagaattta tcagcagttt
    19921 cgaagaaagg gcagacgctc aagacttgct gttcgttaca gggtctctct attttatctc
    19981 agaagtacgg ggctacctgc tggaccgtga gcagataaat tgaccccctt ttttgaactt
    20041 gttatactag gggaattgct ggttagagaa aatttctcta aattggtagc agaaaggaaa
    20101 ttcatcatga aattaaaaag attcacactt tctcttgctt ctctagcaag ttttagtctc
    20161 ttagtagctt gttcacaaag agctcaacag gttcaacagc ctgttgctca gcaggtccaa
    20221 cagcctgctc aacagaatac caatactgca aatgcaggag gtaaccaaaa tcaagcggct
    20281 ccagtacaaa accaacctgt tgctcaaccg accgatattg atgggactta tactggtcag
    20341 gatgacggag accgtatcac tttagtggta actggaacga ctggtacatg gactgagctc
    20401 gaatctgacg gggatcagaa agtcaaacag gttacatttg attcagcaaa tcaacgcatg
    20461 attattggcg atgatgtcaa aatttacact gtaaacggta atcaaatcgt cgtagatgat
    20521 atggatagag acccatcgga ccaaatcgtt ttaactaaat aagactatgc aagtagaaag
    20581 ggctggattt ttcagccttt ttacttttac ctagaaaata atcataaata cttgccttct
    20641 accgaatacc tgcgttatac tagtatcaat tacttgtttt tagcattcaa actatcaagg
    20701 aggggatatg aaatatagga aatttcaatt attgatgtcc aagtatggct ttagtctttc
    20761 gattatgcta cttgaacttt gtcttgtttt tggtctcttt ctttatttag gacgcatggc
    20821 tcccatttta tggattactg tcctcattct actgagtatc atcacaatca tttcgatagt
    20881 caaccgtaat acgactcctg agaataaggt aacctggttg ttagtagcct ttgtgccagt
    20941 atttggtccc ttgctctatc tgatgtttgg tgaaaggcga ttgtccaaaa aagaaatcaa
    21001 acaactgaag aagctaggct ctatgcattt ccaagaagca aatagccagc tactaaaaga
    21061 gaaattaaaa gaaagtgaca aggcagctta tggagtcatc aagtccttat tgagtatgga
    21121 taccaatgct gacatctatg atcaaactgc ctctacattt tttcctaacg gagaagctat
    21181 gtggaaaaag atggtagaag atcttaaaaa ggctgagaaa tttattttct tggaatatta
    21241 cattatagaa gaaggtttga tgtggaatcg catactagat atactagagc aaaaggtagc
    21301 tcagggtgta gaggttaaga tgctctatga tgatatcggc tgtatggcta ctttaacagg
    21361 agattatgca catcgacttc gtcagctggg catcgaggcc cataaattca ataaagttat
    21421 tcctcgtttg acagtggctt ataataacag agatcataga aaaatattga ttgttgatgg
    21481 tcagatagcc tatactggtg gggtcaatct ggcagatgag tacattaacc acgtcgagag
    21541 atttggttat tggaaggata gtggaattcg cttagacgga ctagcagtaa aagccctgac
    21601 acgcttattt ttgaccactt ggtacattaa tcgaggagaa attagtgatt ttgatcaata
    21661 tcatttagaa aatcattcta tcccgagtga cggtttaacc attccatacg gaagtggacc
    21721 caagccaatt tttcgagcgc aggtagggaa aaaagtttat cagagtttaa tcaatcaagc
    21781 aacagaatcg gtctatatta cgacacctta tttgattata gattatgatt taacagagac
    21841 aatcaaaaat gcagctatga gaggggtcga tgttcgaatt atcacccctt acataccaga
    21901 taagaagttc attcagttag tcacgagagg agcttatccc gaccttcttt ctgctggtgt
    21961 tcggatttat gagtatagtc caggttttat tcatagtaag cagatgttgg tagacgaaga
    22021 ttttgcggtg gtggggacaa tcaatctcga ctaccggagc ttggtacacc attatgaaaa
    22081 tgcagtctta ctctataaaa ctccttctat aagggaaatc gcccgagatt ttcgaaatat
    22141 atttgcagat tctcaggaag tctatcctca ttctatcaaa acgagctggt atcaaaagct
    22201 tgtaaaagaa atcgcccagc tattcgcccc tatcttataa gaaatctaga acttaggata
    22261 caaaccagcc ctatttttct tgtcttttac taatagaaag aaagaggagg ggaattcatg
    22321 ctaactaagg aagaagtgaa tgatatgatt gagttcaaac agacacattt acaccgcttt
    22381 cgggaaattg aaacctttgt gaaactatgc aaaaaatcac tcaaacagcc atcgcaagct
    22441 gacaatccta ggactttttg atatactaag acagataaat tgaacaggag aaacgatatg
    22501 agtgtgtatg gtagagtaga agaagttcat aaggagaatc gtgaacctct agaataccaa
    22561 atcgaacaag aatcgcatca tcgtgaatca agtcgtcttc ctttggtgaa aattttacta
    22621 tggagtacgc ttgtaacggg gataactcta ggagtaccgc tattactcga cttaatgagt
    22681 gcacaagaag tgcaggattt ttatgcaggt tgggcgcttc atcagacagg gaagatttac
    22741 agcgactatt atggaagtca aggtttgctt tattatttgc tgacttacgt gagtcagggc
    22801 ggatttttct ttgccatctt tgagtggtta gccttggtag caggaggatt tttccttttt
    22861 agatcagcgg acaccttgac agagcaagga gaccaagctg gacatctggt gactattttt
    22921 tacatgctag ttacaggtct tgcttttggt ggaggctatg cgactctttt agcgcttcct
    22981 ttcttattcg cagcctttag tttagttgcg gcttacctaa gcaatccaag ccatgataag
    23041 ggatttgtac ggattgggct agctttggca ggcggatttt tctttgctcc cttatcatcg
    23101 ctcctgttta ttgctgtagt gggtttaggc ttgttggtct ttaaccttgg gcatagacgc
    23161 tttgcgcatg ggttttatca gtttcttgca gtggctttag gtttttcact tgtcttttat
    23221 ccaactgcct actatagtgc tgcaacagga agttttgggg aagcgattag tggtattcgt
    23281 tatcctattg acagtattcg ctttgatttt acttctaaaa ttttagagaa tatgtttttt
    23341 tatggcttgt tgtcccttgg tttgggattt gtggtttgta tctttttagg tctctttcaa
    23401 tccaaaccct ttaaactata cgtcatttcg gttcctgcaa gtcttgttgt aattttaggt
    23461 ttgattttac ttttcttttc acaagagcct ctgcacgctt cttatttgat ggtcgtcttc
    23521 cctgttttcc tacttttatt ggtaaccaat attaagagtc aacagagggg gcgtagtgct
    23581 agaagaagcc gaagagaaac gccagttagc ctatggagtc gtttcttcaa aggaaatcta
    23641 tatctgctag tttttgggtt tgtctatctt ttgtctgttc cttttttgat gaagtttgtc
    23701 ctttatccag taccttatca agaacgtaat cgtcttgctg atttggtaaa agaggagaca
    23761 aatacggaag atgctatcta tgcatgggat gatactgcga ctctttatcg taagagtgag
    23821 cgcttgtcgc catcggcgat tttgtccccg ttgcactata cagcaactga ggaaaatcgt
    23881 aataagttac ttaatgactt gaaagaaaaa caacctaagg tgattgtggt aaatgacaag
    23941 gtggtagtct ggtctgaagt ggaaacactt ttaaaagaaa attaccaaca agtaaagact
    24001 gattactcag agtttaaagt ctataaaatt aaataaccaa atcaatatct tgtgtatttt
    24061 tagaaatttt aggattttta acacaagata ttgatttttc tttttagagt ggtataatac
    24121 tttttagaaa gaacatttta gaaaagagca tgcgtatgat tgcactagaa gaaaaaatta
    24181 caattttgcc aactctcttc gtcgagaaac gagatgggag acgtgttgta tttgatgtgg
    24241 acaagattga caaggctctc cacaaggcgg ctgacaaggt tatggatgtg acacccctgg
    24301 ttgaaaaacg cctcaatgat ctgactgagc gaattattac agaaattcat agtcgctttc
    24361 cacagggaat taagatttac gaaattcaaa atatcgtaga acatgaactc cttgaagcca
    24421 aagaatatgc gctggctgag gagtatatta cttatcggac acagagggat tttgagcgct
    24481 caaaagcgac ggatatcaac tttagtattc ataaacttct caacaaagac cagacagttg
    24541 tcaatgaaaa tgctaataaa gacagtgatg tctttaacac tcagcgtgat ttgacagcag
    24601 ggattgttgg gaaatcaatc ggactgcaaa tgcttcctaa gcacgtagcc aatgcccacc
    24661 aaaaggggga tatccactat cacgatttgg actacagtcc ctatacccct atgaccaact
    24721 gctgtttgat tgattttaag ggtatgttgg aaaatggttt taagattgga aatgcagagg
    24781 tagagagtcc caagtctatc cagactgcga cagcacagat ttctcaaatc attgccaacg
    24841 ttgcttctag ccagtacggt ggctgttcag ctgaccgtat cgatgaaatt ttggcgcctt
    24901 atgcagagaa gaactatcaa aaacatctca aagatgcaga agagtgggta ttgcctgaaa
    24961 aacgggaaga ttacgcttgg aagaaaacgc aaaaggacat ctacgatgcc atgcaatctc
    25021 ttgagtatga aatcaatact ctcttcactt caaatggaca aacacctttt acttcgttag
    25081 gttttggtct gggaaccagt cgttttgaac gagaaattca aaaagctatt ttaaacattc
    25141 gcatcaaggg tcttggttca gaacaccgta cggctatctt tcctaaactt attttcactc
    25201 tgaaaagagg ccttaattta gaggaaggaa ctcccaacta cgacatcaag cagttggctc
    25261 ttgagtgtgc aaccaaacgg atgtatccag atgttttatc ttacgataag attgttgact
    25321 tgacaggatc cttcaaggtg cctatgggtt gccgttcttt cctccaagga tggaaggatg
    25381 aaaatggtgt agaagtcaat tcaggtcgca tgaatctggg tgttgtgacg gttaatctgc
    25441 ctcgtattgc tcttgagtct gaaggtgata tgaataagtt ctgggaaatc ttcaacgagc
    25501 gcatgaatat cgcagaagat gctcttgttt accgtgtcga acgcactaaa gaggcgacac
    25561 cagcgaatgc tcctatcctt tatcagtacg gtgcttttgg ccatcatcta ggtaaagaag
    25621 aaagtgttga ccagctcttt aagaatcgtc gtgcgaccgt ttcgctgggc tatatcggct
    25681 tgtatgaagt agcgacagtt ttctttggta acagctggga aagtaatcca gatgctaagg
    25741 aattcacgct agacatcatt cacgatatga aacgccgtgt agaagagtgg tcagaccaat
    25801 atggctacca tttctctatc tactcaacac catccgaaag tctgacagac cgtttctgcc
    25861 gactagatat agacaagttt ggctctattc ctgatatcac agacaaggaa tactacacca
    25921 actctttcca ctacgatgtt cgtaaaaatc caacaccgtt tgaaaaattg gactttgaga
    25981 aagtctatcc agaagcaggt gcgtcaggtg gtttcatcca ttattgtgag tatccagtcc
    26041 ttcagcaaaa tccaaaggcc ttggaagctg tctgggatta tgcttatgac cgtgtaggct
    26101 atctaggcac caatactccg attgaccgtt gctacaagtg tgactttgaa ggggattttg
    26161 aaccaactga gagagggttt gcttgtccaa actgtggcaa tagcgaccct aaaacagtag
    26221 atgtggtgaa gcgaacttgt ggctacctag gtaatcctca agcaagaccg atggtcaacg
    26281 ggcgtcacaa ggaaatcgct gcgcgtgtca aacatatgaa tggttcaacg attaaaatag
    26341 ctgggcatca agtaacaaat tagaaagaaa tgaaatggga aaatatcaac tagacgataa
    26401 ggggcgcgca caagtgaccc gttatcacga gaaacactct aaaggtggag ctggtaagaa
    26461 agaacgcttg cttagcttca gagaacaatt tttaaacaag aacaagaaaa aataaaagtg
    26521 agagccagct ctcgcttttc tcatagtggg aggtaaggat ggaattacgc agaccaagat
    26581 tagcggataa gaaagctgtt ttagatatga tgacagagtt tgaaaaattt cagtcgcctc
    26641 acgacggcgg tttctgggat acagagaact ttgtgtatga agactggtta gaaagcaatc
    26701 aggaacagga aatgggaatt aatctgcctg aaggatgggt tcctgcaatt cagttagtgg
    26761 ctttttctga gaaaggtcaa gcagttggat ttcttaatct ccggttgcgc ctcagtaact
    26821 ttctactaga agaaggtggg cacattggct actccatccg tccatctgaa agaggcaagg
    26881 gttatgcaaa agagactctc cgtcagggct tgcaagttgc taaggaaaag aacatcaaga
    26941 aagctctggt gacctgtagc gtgaataatc ctgctagcag agcagtcatt ctagcaaatg
    27001 gtggaatatt tgaggatgct cgcaatggag tcgagcgtta ttggatagag gtagcgaatg
    27061 aataatccaa aaccacaaga atggaaaagc gaggaactta gtcaaggtcg tatcattgac
    27121 tacaaggcct ttaactttgt tgatggcgaa ggcgtgcgta actctctcta tgtagcaggc
    27181 tgtatgtttc actgcgaggg atgttataat gttgcgactt ggtcttttaa tgctggcatt
    27241 ccctatacag cagaattaga agagcagatc atggcagatc ttggtcagcc ctatgttcaa
    27301 ggtttgactt tgttgggagg ggagcctttt ctcaatactg gcattctctt gccacttgtt
    27361 aagcggattc ggaaagaatt gtcagacaag gacatctggt cctggaccgg ctacacttgg
    27421 gaagaaatga tgttggaaac tccagataaa ctggaactct tgtcactgat tgatattctt
    27481 gtcgatggaa gatatgatcg aactaagaga aatcttatgc tccagtttcg aggttcgtct
    27541 aaccaacgaa ttatcgatgt gcaaaaatcg ctcaaaagtg ggcaagtagt gatttgggac
    27601 aagctcaatg acggaaaaga aagctatgaa caggtgaaga gagaatgaag aaaaaaggct
    27661 tagtagacca actagtctca gagatcgaga cggggaaagt caggacactg ggaatatacg
    27721 gtcatggagc ttcaggtaaa tcaacctttg cacaggaatt gtcccaagct ttagattcta
    27781 ctacagtaaa tttgctagaa acagatccct atatcacctc cggacgctat ttggtagtac
    27841 ccaaggacgc gccgaatcaa aaggtgacag ccagtctgcc agtggcgtat gaactggaga
    27901 gtttgcagag agatatcttt gccttgcagg cgggtatgga tgtcttgaca attgaagaac
    27961 cttggaaggc tagtgaagtc ttgtctggag ccaaaccaat tttgattgtc gaagggatgt
    28021 ctgttggttt tctacccaag gaactctttg aaaaaaccat ctgtttctac acggatgagg
    28081 agaccgaatt aaagcgacgc cttgctagag atacgactgt gagaaatcgc gatgcatcct
    28141 ttatattggc tagccatcag atgagacggg agcagtatct gcgatactat aaagaaactg
    28201 agtctaaggc ggatatctta gtggaccaat cagaagataa atttgatgtc aagaggactt
    28261 aacttatgta tagaagaaaa tccctaattt tagaaagaaa aagtaggaaa acagtttcat
    28321 ctcaaaaaaa cgaaaaaacc taacaaatcc cttgcaatcg caggggattt gtgttattct
    28381 attatggtgc tgtaaattac agccttagtt ttgatgcaag aggttgcgac acgctcggtt
    28441 gcattgccac gcaacgccgc gtcggttttc ttgtggagct agcctattat cttaaataga
    28501 cgaaaaggag aaaaagatgg caaacaaaaa aatccgtatc cgtttgaaag cttacgaaca
    28561 ccgtacgctt gacacagcgg ctgcaaaaat cgtagaatca gctactcgta caggtgcaca
    28621 agttgcgggt ccaatcccac ttccaactga acgtagcctc tacacaatca ttcgtgcgac
    28681 tcacaaatac aaagactctc gcgaacaatt tgaaatgcgt acacacaaac gtttgatcga
    28741 tatcgttaac ccaactcaaa aaacagttga tgccttgatg aaattggatc ttccaagtgg
    28801 tgtaaacgta gaaatcaaac tttaatctaa aatataaaag agcagaggct ggtgtttcaa
    28861 tctaattgaa cacgggctaa actcggtgtg aaaaagataa acttcctcgc gtctgctaga
    28921 cactgcgtta gtttcctatt ttcactttga gtttgacgcc ctttgtatct tagacttgag
    28981 cataaaaaac gctcgttaaa aactttttga ataaaaaata tagaaaagga actattttct
    29041 catgacaaaa ggaatcttag ggaaaaaagt gggaatgact caaatcttca ctgaagctgg
    29101 cgaattgatc cctgtaacag ttattgaagc aactccaaac gttgttcttc aagttaaaac
    29161 tgttgaaaca gacggataca acgctatcca agttggtttc gatgacaaac gcgaagtatt
    29221 gagcaacaaa cctgctaaag gacatgtagc gaaagctaac acggctccta agcgcttcat
    29281 tcgtgaattc aaaaacgttg aaggcttgga agttggtgct gaaattacag ttgaaacatt
    29341 cgcagctgga gacgttgttg acgtaactgg tacttctaaa ggtaaaggtt tccaaggtgt
    29401 tatcaaacgc cacggacaat cacgtggacc aatggctcac ggttctcgtt accaccgtcg
    29461 tccaggttct atgggacctg ttgcacctaa ccgcgtattc aaaggtaaaa accttgcagg
    29521 gcgtatgggt ggcgaccgcg taacaattca aaaccttgaa gttgtacaag ttgttccaga
    29581 aaagaacgtt atccttatca aaggtaacgt accaggtgct aagaaatctc ttatcactat
    29641 caaatcagca gttaaagctg gtaaataata aagaaagggg aaatcagtca caatggcaaa
    29701 cgtaacatta tttgaccaaa ctggtaaaga agctggccaa gttgttctta gcgatgcagt
    29761 atttggtatc gaaccaaatg aatcagttgt gtttgatgta atcatcagcc aacgcgcaag
    29821 ccttcgtcaa ggaacacacg ctgttaaaaa ccgctctgca gtatcaggtg gtggacgcaa
    29881 accatggcgt caaaaaggaa ctggacgtgc tcgtcaaggt tctatccgct caccacaatg
    29941 gcgtggtggt ggtgttgtct tcggaccaac tccacgttca tacggctaca aacttccaca
    30001 aaaagttcgt cgcctagctc ttaaatcagt ttactctgaa aaagttgctg aaaacaaatt
    30061 cgtagctgta gacgctcttt catttacagc tccaaaaact gctgaatttg caaaagttct
    30121 tgcagcattg agcatcgatt ctaaagttct tgttatcctt gaagaaggaa atgaattcgc
    30181 agctctttca gctcgtaacc ttccaaacgt gaaagttgca actgctacaa ctgcaagtgt
    30241 tcttgacatc gcaaatagcg acaaacttct tgtcacacaa gcagctatct ctaaaatcga
    30301 ggaggttctt gcataatgaa tttgtatgat gttatcaaaa aacctgtcat cactgaaagc
    30361 tcaatggctc aacttgaagc aggaaaatat gtatttgaag ttgacactcg tgcacacaaa
    30421 cttttgatca agcaagctgt tgaagctgct ttcgaaggtg ttaaagttgc caatgttaac
    30481 acaatcaacg taaaaccaaa agctaaacgt gttggacgtt acactggttt tactaacaaa
    30541 actaaaaaag ctatcatcac acttacagct gattctaaag caatcgagtt gtttgctgct
    30601 gaagctgaat aatctaagga ggaaatatcg tgggaattcg tgtttataaa ccaacaacaa
    30661 acggtcgccg taatatgact tctttggatt tcgctgaaat cacaacaagc actcctgaaa
    30721 aatcattgct tgttgcattg aagagcaagg ctggtcgtaa caacaacggt cgtatcacag
    30781 ttcgtcacca aggtggtgga cacaaacgtt tctaccgttt ggttgacttc aaacgtaata
    30841 aagacaacgt tgaagcagtt gttaaaacaa tcgagtacga tccaaaccgt tctgcaaaca
    30901 tcgctcttgt acactacact gacggtgtga aagcatacat catcgctcca aaaggtcttg
    30961 aagtaggtca acgtatcgtt tcaggtccag aagcagatat caaagtcgga aacgctcttc
    31021 cacttgctaa catcccagtt ggtactttga ttcacaacat cgagttgaaa ccaggtcgtg
    31081 gtggtgaatt ggtacgtgct gctggtgcat ctgctcaagt attgggttct gaaggtaaat
    31141 acgttcttgt tcgtcttcaa tcaggtgaag ttcgtatgat tcttggaact tgccgtgcta
    31201 cagttggtgt tgtcggaaac gaacaacatg gacttgtaaa ccttggtaaa gcaggacgta
    31261 gccgttggaa aggtatccgc ccaacagttc gtggttctgt aatgaaccct aacgatcacc
    31321 cacacggtgg tggtgaaggt aaagcaccag ttggtcgtaa agcaccatct actccatggg
    31381 gcaaacctgc tcttggtctt aaaactcgta acaagaaagc gaaatctgac aaacttatcg
    31441 ttcgtcgtcg caacgagaaa taatattaaa ctagtcgctt aagcaactag taaatccgcc
    31501 agctcggtag cgctccatag gagtgcaagc cgctgtggta caacatttaa aggagaaaat
    31561 ataaaaatgg gacgcagtct taaaaaagga cctttcgtcg atgagcattt gatgaaaaaa
    31621 gttgaagctc aagctaacga cgaaaagaaa aaagttatta aaacttggtc acgtcgttca
    31681 acgatcttcc caagtttcat tggttacact attgcagttt atgacggacg taaacacgta
    31741 cctgtttaca tccaagaaga catggtaggc cacaaacttg gtgaatttgc accaactcgt
    31801 acttacaaag gtcacgctgc agacgacaag aaaacacgta gaaaataagg agaacataaa
    31861 tggcagaaat tacttcagct aaagcaatgg ctcgtacagt acgtgtttca cctcgtaaat
    31921 cacgtcttgt tcttgataac atccgtggta aaagcgtagc cgatgcaatc gcaatcttga
    31981 cattcactcc aaacaaagct gctgaaatca tcttgaaagt tttgaactca gctgtagcta
    32041 acgctgaaaa caactttggt ttggataaag ctaacttggt agtatctgaa gcattcgcaa
    32101 acgaaggacc aactatgaaa cgtttccgtc cacgtgcgaa aggttcagct tcaccaatca
    32161 acaaacgtac agctcacatc actgtagctg ttgcagaaaa ataaggaggt aaaatcgtgg
    32221 gtcaaaaagt acatccaatt ggtatgcgtg tcggcatcat ccgtgattgg gatgccaaat
    32281 ggtatgctga aaaagaatac gcggattacc ttcatgaaga tcttgcaatc cgtaaattcg
    32341 ttcaaaaaga acttgctgac gcagcagttt caactattga aatcgaacgc gcagtaaaca
    32401 aagttaacgt ttcacttcac actgctaaac caggtatggt tatcggtaaa ggtggtgcta
    32461 acgttgatgc actccgtgca aaacttaaca aattgactgg aaaacaagta cacatcaaca
    32521 tcatcgaaat caaacaacct gatttggatg ctcaccttgt aggtgaagga attgctcgtc
    32581 aattggagca acgtgttgct ttccgtcgtg cacaaaaaca agcaatccaa cgtgcaatgc
    32641 gtgctggagc taaaggaatc aaaactcaag tatcaggtcg tttgaacggt gcagatatcg
    32701 cccgtgctga aggatactct gaaggaactg ttccgcttca cacacttcgt gcagatatcg
    32761 attacgcttg ggaagaagca gatactacat acggtaaact tggtgttaaa gtatggatct
    32821 accgtggtga agttcttcca gctcgtaaaa acactaaagg aggtaaataa ccaatgttag
    32881 tacctaaacg tgttaaacac cgtcgtgagt tccgtggaaa aatgcgcggt gaagcaaaag
    32941 gtggaaaaga agtagcattc ggtgaatacg gtcttcaagc tacaactagc cactggatca
    33001 ctaaccgcca aatcgaagct gctcgtatcg ccatgactcg ttacatgaaa cgtggtggta
    33061 aagtttggat taaaatcttc ccacacaaat catacactgc taaagctatc ggtgtgcgta
    33121 tgggatctgg taaaggggca cctgaaggtt gggtagcacc agttaaacgt ggtaaagtga
    33181 tgttcgaaat cgctggtgta tctgaagaga ttgcacgtga agcgcttcga cttgctagcc
    33241 acaaattgcc agttaaatgt aaattcgtaa aacgtgaagc agaataagga gaaggcatga
    33301 aacttaatga agtaaaagaa tttgttaaag aacttcgtgg tctttctcaa gaagaactcg
    33361 cgaagcgcga aaacgaattg aaaaaagaat tgtttgaact tcgtttccaa gctgctactg
    33421 gtcaattgga acaaacagct cgcttgaaag aagttaaaaa acaaatcgct cgtatcaaaa
    33481 cagttcaatc tgaagcgaaa taatagacta gggaaggaga aatttcaatg gaacgcaata
    33541 atcgtaaagt tcttgttgga cgtgttgtat ctgacaaaat gaacaagaca atcacagttg
    33601 tagttgaaac aaaacgtaac cacccagtct atggtaaacg tattaactac tctaaaaaat
    33661 acaaagctca tgatgaaaac aatgttgcca aagaaggcga tatcgtacgt atcatggaaa
    33721 ctcgcccgct ttcagctaca aaacgtttcc gtcttgtaga agttgttgaa gaagcggtca
    33781 tcatctaatc aaacctgaaa ggagaaaact gaaatgattc aaacagaaac tcgtttgaaa
    33841 gtcgcagaca acagcggtgc tcgcgaaatc ttgactatca aagttcttgg tggttcagga
    33901 cgtaaatttg caaacatcgg tgatgttatc gtggcatctg taaaacaagc tactcctggt
    33961 ggtgcggtta aaaaaggtga cgttgttaaa gcagttatcg ttcgtactaa atcaggtgct
    34021 cgtcgtgctg atggttcata catcaaattt gacgaaaacg cagcagttat catccgtgaa
    34081 gacaaaactc ctcgcggaac acgtatcttt ggcccagttg cacgtgaatt gcgtgaaggt
    34141 ggcttcatga agatcgtgtc acttgctcca gaagtacttt aatttttagg aacaaactag
    34201 tcccctagct tcaagctagg gtgcccttat gggcgtaaga aaaatcaagg agaaacctaa
    34261 tgtttgtaaa aaaaggcgac aaagttcgcg taatcgctgg taaagacaag ggaacagaag
    34321 ctgttgtcct tactgccctt ccaaaagtaa acaaagttat cgttgaaggt gttaacattg
    34381 ttaagaaaca ccaacgtcca actaacgagc ttcctcaagg tggtatcatc gagaaagaag
    34441 cagctatcca cgtatcaaac gttcaagttt tggacaaaaa tggtgtagct ggtcgtgttg
    34501 gatacaaatt tgtagacggt aaaaaagttc gctacaacaa aaaatcaggc gaagtgcttg
    34561 attaatcacg aaggaaagga gaagtataat ggcaaatcgt ttaaaagaaa aatatcttaa
    34621 tgaagtagtt cctgctttga cagaacaatt caactactca tcagtgatgg ctgtgcctaa
    34681 agtagataag attgttttga acatgggtgt tggtgaagct gtatcaaacg ctaaaagcct
    34741 tgaaaaagct gctgaagaat tggcacttat ctcaggtcaa aaaccactta tcactaaagc
    34801 taaaaaatca atcgccggct tccgtcttcg tgaaggtgtt gcgatcggtg caaaagttac
    34861 ccttcgtggt gaacgtatgt acgaattctt ggataaattg gtatcagttt cacttccacg
    34921 tgtacgtgac ttccacggtg tcccaacaaa atcatttgat ggacgcggga actacacact
    34981 tggtgtgaaa gaacaattaa tcttcccaga aatcaacttc gatgacgttg acaaaactcg
    35041 tggtcttgac atcgttatcg taacaactgc taacactgac gaagagtcac gtgcattgct
    35101 tacaggcctt ggaatgcctt ttgcaaaata atataggagg taaatctaat ggctaaaaaa
    35161 tcaatggtag ctagagaggc taaacgccaa aaaattgttg accgttatgc tgaaaaacgt
    35221 gctgcattaa aggcggcagg ggactacgaa ggtttatcta aattacctcg caacgcctca
    35281 ccgactcgtt tacataatcg ttgtagagtt acggggcgcc cacattcagt ttaccgcaaa
    35341 tttggtctga gtcgtatcgc ttttcgcgaa cttgcgcata aaggtcaaat tcctggtgta
    35401 acaaaagcat cttggtaatt taagatatca agggtgtcaa aactccaagt aaaaatagga
    35461 aacttgacga agaaactaaa gtttctagga aagtttatct ttttcacaca gagtttagcc
    35521 cgggttcaat tgggcttgcc aatttgaacc cgagctacag ctttggcaaa aaagaccaat
    35581 ttgctttgga gcattgcttc tgcattaaat tgtctatttt tgctcgtgct gttacgctct
    35641 ttgtatcatg tattaactag caagtgcaac ttgcaaacta ctagtaagag gagaaaaaca
    35701 aaatggttat gactgaccca atcgcagact tcctaactcg tattcgtaat gctaaccaag
    35761 ctaaacacga agtacttgaa gtacctgcat caaacatcaa aaaagggatt gctgaaatcc
    35821 ttaaacgcga aggttttgta aaaaacgttg aaatcattga agatgacaaa caaggcgtca
    35881 tccgtgtatt tcttaaatac ggaccaaatg gtgagaaagt tatcactaac ttgaaacgtg
    35941 tttctaaacc aggacttcgt gtctacaaaa aacgtgaaga ccttccaaaa gttcttaacg
    36001 gacttggaat tgccatcctt tcaacttctg aaggtttgct tactgataaa gaagcacgcc
    36061 aaaagaatgt tggtggtgag gttatcgctt acgtttggta aaatcaagat acaaagctcg
    36121 taaagaacaa agcaaaatta ggaagttgga gaagtttgtt tacaaacaag ccaacttatc
    36181 tattttgcac agttcttaga gcgtgttcag ttcagctctt gaactaaata agtatctgaa
    36241 ccccgtgaaa actggccgtt ctggcctgac aatttaacag gagaaaataa acatgtcacg
    36301 tattggtaat aaagttatcg tgttgcctgc tggtgttgaa ctcgctaaca atgacaacgt
    36361 tgtaactgta aaaggaccta aaggagaact tactcgtgag ttctcaaaag atattgaaat
    36421 ccgtgtggaa ggtactgaag taactcttca ccgtccaaac gattcaaaag aaatgaaaac
    36481 tatccacgga actactcgtg cccttttgaa caacatggtt gttggtgtat cagaaggatt
    36541 caagaaagaa cttgaaatgc gtggggttgg ttaccgtgca cagcttcaag gatctaaact
    36601 tgttttggct gttggtaaat ctcatccaga cgaagttgaa gctccagaag gaattacttt
    36661 tgaacttcca aacccaacaa caatcgttgt tagcggaatt tcaaaagaag tagttggtca
    36721 aacagctgct tacgtacgta gccttcgttc accagaacca tataaaggta aaggtatccg
    36781 ttacgttggt gaattcgttc gccgtaaaga aggtaaaaca ggtaaataat gttgagtggt
    36841 tgatcatcaa ccaccaacct attttccaac tttgtgcata gcacacgatt taaaactaaa
    36901 gaggtgaaaa ctgtgatttc aaaaccagat aaaaacaaac tccgccaaaa acgtcaccgt
    36961 cgcgttcgcg gaaaactctc tggaactgct gatcgcccac gtttgaacgt attccgttct
    37021 aatacaggca tctacgctca agtgattgat gacgtagcgg gtgtaacgct cgcaagtgct
    37081 tcaactcttg ataaagaagt ttcaaaagga actaaaactg aacaagccgt tgctgtcggt
    37141 aaactcgttg cagaacgtgc aaacgctaaa ggtatttcag aagtggtgtt cgaccgcggt
    37201 ggatatctat atcacggacg tgtgaaagct ttggctgatg cagctcgtga aaacggattg
    37261 aaattctaat aggaggacac tagaaaatgg catttaaaga caatgcagtt gaattagaag
    37321 aacgcgtagt tgctgtcaac cgtgttacaa aagttgttaa aggtggacgt cgtcttcgtt
    37381 tcgcagctct tgttgttgtt ggtgaccaca atggtcgcgt aggatttggt actggtaaag
    37441 ctcaagaagt tccagaagca atccgtaaag cagtagatga tgctaagaaa aacttgatcg
    37501 aagttcctat ggttggaaca acaatcccac acgaagttct ttcagaattc ggtggagcta
    37561 aagtattgtt gaaacctgct gtagaaggtt ctggagttgc cgctggtggt gcagttcgtg
    37621 ccgttgtgga attggcaggt gtggcagata ttacatctaa atcacttggt tctaacactc
    37681 caatcaacat tgttcgtgca actgttgaag gtttgaaaca attgaaacgc gctgaagaaa
    37741 ttgctgccct tcgtggtatt tcagtttctg atttggcata agaaagggga taaaatggct
    37801 caaattaaaa ttactttgac taagtctcca atcggacgca ttccatcaca acgtaaaact
    37861 gttgtagcac ttggacttgg caaattgaac agctctgtta ttaaagaaga taacgctgct
    37921 atccgtggta tgatcacagc agtatctcac ttagtaacag ttgaagaagt aaactaatga
    37981 agttttaggg gatgtgcact gtaccatccc ctaaaactag atatagtcat ctatgatgac
    38041 atcgtatagg cgagttgatg ggggagacaa ccttttctcc cttatcggcg ctagcatttt
    38101 acaaaagagg agaaaataaa aatgaaactt catgaattga aacctgcaga aggttctcgt
    38161 aaagtacgta accgcgttgg tcgtggtact tcatcaggta acggtaaaac atctggtcgt
    38221 ggtcaaaaag gtcaaaaagc tcgtagcggt ggcggagttc gccttggttt tgaaggtgga
    38281 caaactccat tgttccgtcg tcttccaaaa cgtggattca ctaacatcaa cgctaaagaa
    38341 tacgcaattg tgaaccttga ccaattgaac gtctttgaag atggtgctga agtaactcca
    38401 gttgttctta tcgaagcagg aattgttaaa gctgaaaagt caggtattaa aattcttggt
    38461 aacggtgagt tgactaagaa attgactgtg aaagcagcta aattctctaa atcagctgaa
    38521 gaagctatca ctgctaaagg tggttcagta gaagtcatct aagagaggtg acctatgttt
    38581 tttaaattat taagagaagc tcttaaagtc aagcaggttc gatcaaaaat tttatttaca
    38641 atttttatcg ttttggtctt tcgtatcgga actagcatta cagttcctgg tgtgaatgcc
    38701 aatagcttga atgctttaag tggattatcc ttcttaaaca tgttgagctt ggtgtcgggg
    38761 aatgccctaa aaaacttttc gatttttgcc ctaggagtta gtccctatat caccgcttct
    38821 attgttgtcc aactcttgca aatggatatt ttacccaagt ttgtagagtg gggtaaacaa
    38881 ggggaagtag gtcgaagaaa attgaatcaa gctactcgtt atattgctct agttctcgct
    38941 tttgtgcaat ctatcgggat tacagctggt tttaatacct tggctggagc tcaattgatt
    39001 aaaactgctt taactccaca agtttttctg acgattggta tcatcttaac agctggtagt
    39061 atgattgtca cttggttggg tgagcaaatt acagataagg gatacggaaa cggtgtttcc
    39121 atgattatct ttgccgggat tgtttcctca attccagaga tgattcaggg catctatgtg
    39181 gactactttg tgaacgtccc aagtagccgt atcacttcat ctatcatttt cgtaatcatt
    39241 ttgattatta ctgtattgtt gattatttac tttacaactt atgttcaaca agcagaatac
    39301 aaaattccaa tccaatatac taaggttgca caaggtgctc catctagctc ttaccttccg
    39361 ttaaaggtaa accctgctgg agttatccct gttatctttg ccagttcgat tactgcagcg
    39421 cctgcggcta ttcttcagtt tttgagtgcc acaggtcatg attgggcttg ggtaagggta
    39481 gcacaagaga tgttggcaac tacttctcca actggtattg ccatgtatgc tttgttgatt
    39541 attctcttta cattcttcta tacgtttgta cagattaatc ctgaaaaagc agcagagagc
    39601 ctacaaaaga gtggtgccta tatccatgga gttcgtcctg gtaaaggtac agaagaatat
    39661 atgtctaaac ttcttcgtcg tcttgcaact gttggttccc tcttccttgg tgtgatttcc
    39721 attttaccga ttgcagctaa agatgtattt ggtctttctg atgttgttgc ctttggtgga
    39781 acaagtctct tgatcattat ctctacaggt atcgaaggaa tcaagcaatt ggaaggttac
    39841 ctattgaaac gtaagtatgt tggtttcatg gacagaacag aataaaagta tttactgaat
    39901 cagtaaatac tgagggagtg gaggtttaaa ctctgacatt tgtaagagtt ggatctcccc
    39961 tcttctattt tgtttttaaa taggggtgaa aagacttttt gcttctattt aaaaataaaa
    40021 taaggagatc aaatcatgaa tcttttgatt atgggcttac ctggtgcagg taagggaact
    40081 caagcagcaa aaatcgtaga acaattccat gttgcacata tctcaacagg tgatatgttc
    40141 cgcgctgcaa tggcaaatca aactgaaatg ggtgttcttg ctaagtcata tattgacaag
    40201 ggtgaattgg ttcctgacga agttacaaat ggaatcgtaa aagaacgcct ttcacaagat
    40261 gatattaaag aaacaggatt cttattggat ggttacccac gtacaattga acaagctcat
    40321 gccttggaca aaacattggc tgaacttggc attgaactag aaggtattat caatattgaa
    40381 gtgaaccctg acagcctctt ggaacgtttg agtggccgta tcatccaccg cgtaactgga
    40441 gaaactttcc acaaggtctt taacccacca gttgactata aagaagaaga ttactaccaa
    40501 cgtgaagatg ataagcctga gacagtaaaa cgtcgtttgg atgttaatat tgctcaagga
    40561 gaaccaatca ttgctcacta ccgtgccaaa ggtttggttc atgacatcga aggtaatcaa
    40621 gatatcaatg atgtcttctc agatattgaa aaagtattga caaatttgaa ataaagcgtt
    40681 tttcgcactt gcaaaaatcc gctacaaatg ttatactgag atagtctgac ttataattgt
    40741 tgtctctgtg tctagaggca tcgaatcgaa atttatggag gtgcttttgc gtggcaaaag
    40801 acgatgtgat tgaagttgaa ggcaaagtag ttgatacaat gccgaatgca atgtttacgg
    40861 ttgaacttga aaatggacat cagattttag caacagtttc tggtaaaatt cgtaaaaact
    40921 atattcgtat tttagcggga gatcgtgtta ctgtcgaaat gagtccatat gacttgacac
    40981 gtggacgtat cacttaccgc tttaaataat cgaaaaactt ggagggataa gaaatgaaag
    41041 taagaccatc ggtcaaacca atttgcgaat actgtaaagt tattcgtcgt aatggtcgtg
    41101 ttatggtaat ttgcccagca aatccaaaac acaaacaacg tcaaggataa gatagaaagg
    41161 agaaaacatg gctcgtattg ctggagttga tattccaaat gacaaacgcg tagtaatctc
    41221 attgacttat gtttatggta tcggacttgc aacatctaag aaaattttgg ctgctgctgg
    41281 aatctcagaa gatgttcgtg tacgtgatct tacatcagat caagaagatg ctatccgtcg
    41341 tgaagtggat gcaatcaaag ttgaaggtga ccttcgtcgt gaagtaaact tgaacatcaa
    41401 acgtttgatg gaaatcggtt cataccgtgg tatccgtcac cgtcgtggac ttcctgtccg
    41461 tggacaaaac actaaaaaca acgctcgcac tcgtaaaggt aaagctgttg cgattgctgg
    41521 taagaaaaaa taatatagga ggtaaaagtc ttggctaaac caacacgtaa acgtcgtgtg
    41581 aaaaagaata tcgaatctgg tattgctcat attcacgcta catttaataa cactattgtt
    41641 atgattactg atgtgcatgg taatgcaatt gcttggtcat cagctggtgc tcttggtttc
    41701 aaaggttctc gtaaatctac accattcgct gctcaaatgg cttctgaagc tgctgctaaa
    41761 tctgcacaag aacacggtct taaatcagtt gaagttactg taaaaggtcc aggttctggt
    41821 cgtgagtcag ctattcgtgc gcttgctgcc gctggtcttg aagtaacagc aattcgtgat
    41881 gtgactccag tgccacacaa tggtgctcgt cctccaaaac gtcgccgtgt ataatcatcg
    41941 cattacactg cttttcgttt aagagggagt aactaaatga tcgagtttga aaaaccaaat
    42001 ataacaaaaa ttgatgaaaa taaagattat ggcaagtttg taatcgaacc acttgaacgt
    42061 ggctacggta caactcttgg taactctctt cgtcgtgtac ttctagcttc tctaccagga
    42121 gcagctgtga catctatcaa cattgatggt gtgttacatg agtttgacac agttccaggt
    42181 gttcgtgaag acgtgatgca aatcattctg aacattaaag gaattgcagt gaaatcgtac
    42241 gttgaagacg aaaaaatcat cgaactggat gttgaaggtc ctgctgaagt aacagctggt
    42301 gacattttga cagatagcga tattgaaatt gtaaatccag atcattatct ctttacaatc
    42361 ggtgaaggtt cttctctaaa agcgactatg actgttaaca gtggtcgtgg atatgtacct
    42421 gctgatgaaa ataaaaagga taatgcacca gttggaacac ttgctgtaga ttctatttat
    42481 acaccagtta caaaagtcaa ctatcaagtg gaacctgctc gtgtaggtag caatgatggt
    42541 ttcgacaaat taacccttga aatcttgaca aatggaacaa ttattccaga agatgcttta
    42601 gggctttcag cacgtatttt gacagaacat cttgatttgt ttacaaatct tactgagatt
    42661 gctaagtcaa ctgaagtgat gaaagaagct gatactgaat ctgacgaccg tattttagat
    42721 cgtacgattg aggaactgga cttgtctgtg cgttcataca actgtttaaa acgtgccggt
    42781 atcaatactg tgcatgattt gacagaaaaa tctgaagcag agatgatgaa agtacgaaat
    42841 cttggacgca agagtttgga agaagtgaaa ctcaaactca ttgatttggg tcttggatta
    42901 aaagataaat aaaggaggaa tacatggctt accgtaaact aggacgcact agctcacaac
    42961 gtaaagcaat gcttcgcgat ttgacaactg accttttgat caacgaatca atcgtgacaa
    43021 ctgaagctcg tgctaaagaa atccgtaaaa ctgttgaaaa aatgattact ctaggtaaac
    43081 gtggtgattt gcatgcacgt cgtcaagcag ctgctttcgt acgtaatgaa atcgcatctg
    43141 aaaactatga tgaagcaact gataagtaca cttctactac agcacttcaa aaattgttct
    43201 cagaaatcgc acctcgttat gctgaacgta acggtggata cactcgtatc cttaaaactg
    43261 aaccacgtcg tggtgatgca gcgccaatgg cgatcatcga attagtataa aatcatcaat
    43321 tttgttgagt gttatgatga tggagtcttg tgctcttagt ctagctctgg tctaccgcta
    43381 ggatttcggt cctagcggga acactcatca taagttggga tagtagacgc ttgtttacga
    43441 aattgttttt ttcttaagaa caacttcgta agcaggcgtt tttgagtatt ttcgttagaa
    43501 ttatgctata ctatttgaaa agaatcctgt ttaatgttaa ggtttcttat tttaagaaga
    43561 attggagttt acttatgaaa gccattataa ctgttgttgg taaagataaa tctggaattg
    43621 ttgcaggtgt ttctggtaaa attgcagaat taggattgaa tattgacgat atctctcaaa
    43681 ctgtcttgga tgaatatttt acgatgatgg ctgttgtatc tagtgatgaa aagcaagatt
    43741 ttacctatct tcgtaatgaa tttgaagctt ttgggcaaac tttgaatgta aaaatcaata
    43801 ttcagagtgc agcgattttc gaagctatgt ataatatcta ggaggtcatc atggatatta
    43861 gacaagttac tgaaaccatc gccatgattg aggagcaaaa cttcgatatt agaaccatta
    43921 ccatggggat ttctcttttg gactgtatcg atccagatat caatcgtgct gcggagaaaa
    43981 tctatcaaaa aattacgaca aaggcggcta atttagtagc tgttggtgat gaaattgcgg
    44041 ctgagttggg aattcctatc gttaataagc gtgtatcggt gacacctatt tctctgattg
    44101 gggcagcgac agatgcgacg gactacgtgg ttctggcaaa agcgcttgat aaggctgcga
    44161 aagagattgg tgtggacttt attggtggtt tttctgcctt agtacaaaaa ggttatcaaa
    44221 agggagatga gattctcatc aattccattc ctcgcgcttt ggctgagacg gataaggtct
    44281 gctcgtcagt caatatcggc tcaaccaagt ctggtattaa tatgacggct gtggcagata
    44341 tgggacgaat tatcaaggaa acagcaaatc tttcagatat gggagtggcc aagttggttg
    44401 tattcgctaa tgctgttgag gacaatccat ttatggcggg tgcctttcat ggtgttgggg
    44461 aagcagatgt tatcatcaat gtcggagttt ctggtcctgg tgtggtgaaa cgtgctttgg
    44521 aaaaagttcg tggacagagc tttgatgtag tagccgaaac agttaagaaa actgccttta
    44581 aaatcactcg tatcggtcaa ttggttggtc aaatggccag tgagagactg ggtgtggagt
    44641 ttggtattgt ggacttgagt ttggcaccaa cccctgcggt tggagactct gtggcacgtg
    44701 tccttgagga aatggggcta gaaacagttg gcacgcatgg aacgacagct gccttggccc
    44761 tcttgaacga ccaagttaaa aagggtggag tgatggcctg taaccaggtc ggtggtctat
    44821 ctggtgcctt tatccctgtt tctgaggatg aaggaatgat tgctgcagtg caaaatggct
    44881 ctcttaattt agaaaaacta gaagctatga cggctatctg ttctgttgga ttggatatga
    44941 ttgccatccc agaagatacg cctgctgaaa ccattgcggc tatgattgcg gatgaagcag
    45001 caatcggtgt tatcaacatg aaaacaacag ctgttcgtat cattcccaaa ggaagagaag
    45061 gcgatatgat tgagtttggt ggtctattag gaactgcacc cgttatgaag gttaatgggg
    45121 cttcgtctgt cgacttcatc tctcgcggtg gacaaatccc agcaccaatt catagtttta
    45181 aaaattaaga aaataggaga aattttaagt tctatttaag attagatgtg tatactataa
    45241 tcattaaata aagacctcct aatattattt gaaacagata acactgaatt agtttgaatt
    45301 tgattttcat ctaatatctt tatttaatga actcctaaac tttttcataa taatctcctt
    45361 caaaagtcgc ctgtatgggt ggcttttatt ttatcattca tgatataata gaagcaaacg
    45421 gaggacggaa aatggtaaaa gtacgattgt atttggtacg tcatggcaag accatgttta
    45481 acacgattgg tcgcgcgcaa ggttggagcg atactccctt aactgctgaa ggtgaacgag
    45541 ggattcaaga gttaggaatc ggtttgcgag aatctgatct acagtttgag cgcgcttatt
    45601 cgagtgattc tggtcgtacc attcagacca tgggaattat acttgaagaa cttggcttgc
    45661 aggggaaaat cccttatcgc atggacaagc gtatcagaga atggtgtttc ggtagttttg
    45721 atggagccta tgatggcgat cttttcatgg gcattattcc tcgtatcttt aatgtggacc
    45781 acgttcacca attgtcttat gctgaactgg ctgagggctt ggtagaggtc gatacagctg
    45841 gttgggctga aggttgggaa aaactcagtg gccgaatcaa ggaaggcttt gaaataattg
    45901 caaaagaaat ggaagatcaa ggtggaggta acgcccttgt tgtcagccat ggaatgacta
    45961 ttggaaccat tgtttatctg attaatggca tgcatccgca tggtctagat aatggtagcg
    46021 tgacgattct tgaatatgag gacggtcagt ttagggttga agttgtcggt gaccgtagtt
    46081 accgagagct aggacgtgag aagatggaag aaggttctat ttaatcagtc tagacttgct
    46141 tgccatgagc tagggatttg ataagaatat caagataaga aaaaacagcc gagggtactc
    46201 ctttcggctg tttttgatgt ggaaaactaa agtgtaatgc tattgctttt agagattttc
    46261 ataaacaaga gcaaggaacc tactgttaga acagtcagga tagttgacaa ggctgcggct
    46321 acaccgtaat ttcctctgag aatctctgta taaatagcca cagtcattgt tcttgttttg
    46381 acattgtaga ggaggataga agtagagagt tttgaaatca ttgtgaccca agataagatg
    46441 gctccagaaa tgataccaga tagcatcatt ggagttgtaa tcttagcaaa gatattgaga
    46501 cgactacttc ctaagctttc agcagcttct tcaatacttg gtgctatttg ttgtaagcta
    46561 gcaacagatg agcgaatagt ataaggtaat cttctgacag atagagacat aatcaagatg
    46621 aaagcagtcc ctgtaatcat aagaaatcca cttccaaata gaccagtatt gaaggaagaa
    46681 atgaaggcaa tccctagaac ggttcctggt acaatataag gtaccatact gaggctgtca
    46741 attaagtttg taaacaaatt ccgttttcta acggctaggt aggagataaa tgtcgcaaat
    46801 agaacaacta gaactaaggc aatcaaaggg atacgaatgg tattgaaaat agcagatccc
    46861 atacgattga aagctacctt gtaactgttt ggagaataac ctttaacaaa taccatacct
    46921 gatgttttta ggaaagaggt ataaattaag tagatttgag gtaaaacaga gataaagata
    46981 attccgtaga ctgttgcata aatggcagcc atttttcctt ttgtagtttt tttaggctca
    47041 attggatgga gcagattcat gctgaaactg tagcggtttg caatgtgttt ttggataagg
    47101 aaaattgcca aggcaatgat aatcgccata attgcaaaag cagaatttcc tccaacctcg
    47161 ctaataaatt gggtataaat caggacaggg aaagtccgat atccttcgcc aatcaacata
    47221 ggcgttccaa agtctgagaa tgctctcata aatacaagca aggagctgct agtaaggttg
    47281 aaactaggag aggtaaaaca accgttacga taggtttaaa tccgaaggac cccatgcttt
    47341 cagctgcttc aagtagagaa ttgtcaatac tgttcattgt tccagcaaca tatagaaata
    47401 ccagtgggaa tagttgcagt gtaaagacaa gtatacttcc tttgaatcca taaatatcga
    47461 tagctggaag atgaagggca tttgtcaaaa atttagtgat gacctcattt cgtctcagca
    47521 agagaatcca ggagtaggct cctacgaaag gagctgacat ggaagcaatg ataatcaata
    47581 tttgtagaaa tttcttcccc ttgaagtcat acatagagaa gagataagct aatagggttc
    47641 ctacaactaa ggaagtgaca gtagcggtaa tggaaaccct gaaactgttg actagtgtct
    47701 cagagtagta ggttttacta aagaaagtga caaaattagc tagtgagaat tgtccttcat
    47761 gtataagtgc ttgcttgagc acggtaacga taggataaac gagaaagaca agataggtaa
    47821 gaaagatgaa gaaagaggaa gctgtccaaa tatttagttt tttacattcc atggttgact
    47881 ccttttatca ggttttggga accatctgca gaaaagatgt ttaatttttg cgtattgatt
    47941 cgtagacgaa tacgattgcc tttttgtagt tcttcttcaa aagttgattc ttcactaact
    48001 tgaatttttg aggcaaaacc tgtctcaatg aaatactccg tatttagtcc aagatagacg
    48061 ctatcgctaa tagttccttc aatatctcca gattcatctt tgataaactc ttcgggacga
    48121 atgcttacat gaatagcttg ctcctcaacc tgatcaagag ctggcattcg aagggcatag
    48181 ccatctgaaa agacgatata agcgccgtcg ctccgttttt caagattggc agggataata
    48241 tttgtgcgtc cgataaaggt tgccacaaac tcattagctg gtttatgata gagttctttt
    48301 ggtcggccga tttgttggat caccccatct ttcataacag caatttggtc tgaaatagcc
    48361 atggcttctt cttggtcgtg ggttacataa acagttgtaa ttcccacttc gtgttggatt
    48421 tctcggatgg cttgacgcat atccaagcga agtttggcct ccagattact aagtggctcg
    48481 tccatgagga gaacacttgg attaaccgct aaggcgcatg ccaaggtgac acgttgttgt
    48541 tgtccaccac tgagtttatc gggttttcga tccgcatatt gagcaatttg catgagttca
    48601 agatacttgt tggtctgttg aatcaattct tcttttgcat aagaccaaaa gcaacgttgt
    48661 ctcggacagt caaatgtggg aaaatagcgt agttttggaa aaccatcccg atattgcgtt
    48721 tgctgggttc catattattg atttttgtat catcgaagta aaattctcaa tctttgatac
    48781 tgttgaaacc tgcaatcata cgaagaaggg tcgttttccc acatcctgaa gctccaagaa
    48841 gggtaaagag acttcctttt ggaattgtaa tgttcaaatt ctcaataaca gggacatcgt
    48901 ggtagatttt tttggcgtta ataattttga tctcactcat agtgaacctc ttttactgtt
    48961 tagattggat atctgtaaag acttcgttgt atttcttaac gatatctgat ttattcttga
    49021 tgacataatc ataatcttca gtgagtgttt tgattttgtc aattggtttc atgttttcgc
    49081 ttgttttagc atttttacga acaggacggt tagtagtggt tgtaccaagt gtatcttgta
    49141 cttcttgaga gataataaaa tcgataaatt tcttggcatt ttccatattt ttagattttt
    49201 taacgatagc agcactagca ggtaggaaga cggttccttc ttttggatag actaccttaa
    49261 tgttagctcc gtcatttaag agtttaactg ctggatcttc ataagagaga ccaacagtca
    49321 tttctccatc agcgactgct ttatagacac cagatgaact taaaccgatt ttatagta
//
LOCUS       DAVBNZ010000008        46527 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000008 DAVBNZ010000000
VERSION     DAVBNZ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46527
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.008"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(<1..463)
                     /locus_tag="VQ860_000472"
     CDS             complement(<1..463)
                     /locus_tag="VQ860_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118961.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCG"
     gene            complement(453..650)
                     /locus_tag="VQ860_000473"
     CDS             complement(453..650)
                     /locus_tag="VQ860_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118962.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(654..1238)
                     /locus_tag="VQ860_000474"
     CDS             complement(654..1238)
                     /locus_tag="VQ860_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118963.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKKFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGDKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPTLGLVLNANDTEVPKELIPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(1636..2061)
                     /locus_tag="VQ860_000475"
     CDS             complement(1636..2061)
                     /locus_tag="VQ860_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118964.1"
                     /translation="MTSRVFIDADCISVFLWVGIEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEGASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(2190..2549)
                     /locus_tag="VQ860_000476"
     CDS             complement(2190..2549)
                     /locus_tag="VQ860_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118965.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMALG"
     gene            complement(2595..2801)
                     /locus_tag="VQ860_000477"
     CDS             complement(2595..2801)
                     /locus_tag="VQ860_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118966.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLER"
     gene            complement(2788..2949)
                     /locus_tag="VQ860_000478"
     CDS             complement(2788..2949)
                     /locus_tag="VQ860_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3118967.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(3308..4264)
                     /gene="lytA"
                     /locus_tag="VQ860_000479"
     CDS             complement(3308..4264)
                     /gene="lytA"
                     /locus_tag="VQ860_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET3118968.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(4640..6010)
                     /locus_tag="VQ860_000480"
     CDS             complement(4640..6010)
                     /locus_tag="VQ860_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3118969.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(6317..7483)
                     /gene="recA"
                     /locus_tag="VQ860_000481"
     CDS             complement(6317..7483)
                     /gene="recA"
                     /locus_tag="VQ860_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET3118970.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(7538..8794)
                     /locus_tag="VQ860_000482"
     CDS             complement(7538..8794)
                     /locus_tag="VQ860_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET3118971.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(8879..9895)
                     /locus_tag="VQ860_000483"
     CDS             complement(8879..9895)
                     /locus_tag="VQ860_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3118972.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(9903..10421)
                     /locus_tag="VQ860_000484"
     CDS             complement(9903..10421)
                     /locus_tag="VQ860_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3118973.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKITGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(10411..10854)
                     /gene="tsaE"
                     /locus_tag="VQ860_000485"
     CDS             complement(10411..10854)
                     /gene="tsaE"
                     /locus_tag="VQ860_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET3118974.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLSEELQYGV"
     gene            complement(10940..11560)
                     /locus_tag="VQ860_000486"
     CDS             complement(10940..11560)
                     /locus_tag="VQ860_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3118975.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(11943..12806)
                     /locus_tag="VQ860_000487"
     CDS             complement(11943..12806)
                     /locus_tag="VQ860_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3118976.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            13310..15325
                     /locus_tag="VQ860_000488"
     CDS             13310..15325
                     /locus_tag="VQ860_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3118977.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLYVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            15327..15959
                     /locus_tag="VQ860_000489"
     CDS             15327..15959
                     /locus_tag="VQ860_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3118978.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            16100..16378
                     /locus_tag="VQ860_000490"
     CDS             16100..16378
                     /locus_tag="VQ860_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET3118979.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(16887..17300)
                     /gene="ndk"
                     /locus_tag="VQ860_000491"
     CDS             complement(16887..17300)
                     /gene="ndk"
                     /locus_tag="VQ860_000491"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET3118980.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(17411..21088)
                     /gene="rpoC"
                     /locus_tag="VQ860_000492"
     CDS             complement(17411..21088)
                     /gene="rpoC"
                     /locus_tag="VQ860_000492"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET3118981.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(21121..24732)
                     /gene="rpoB"
                     /locus_tag="VQ860_000493"
     CDS             complement(21121..24732)
                     /gene="rpoB"
                     /locus_tag="VQ860_000493"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3118982.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            25148..25218
                     /locus_tag="VQ860_000494"
     tRNA            25148..25218
                     /locus_tag="VQ860_000494"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25180..25182,aa:Cys,seq:gca)
     gene            complement(25416..26747)
                     /locus_tag="VQ860_000495"
     CDS             complement(25416..26747)
                     /locus_tag="VQ860_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET3118983.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(27038..27862)
                     /gene="endA"
                     /locus_tag="VQ860_000496"
     CDS             complement(27038..27862)
                     /gene="endA"
                     /locus_tag="VQ860_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET3118984.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(27901..28089)
                     /locus_tag="VQ860_000497"
     CDS             complement(27901..28089)
                     /locus_tag="VQ860_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3118985.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(28082..29365)
                     /gene="murA"
                     /locus_tag="VQ860_000498"
     CDS             complement(28082..29365)
                     /gene="murA"
                     /locus_tag="VQ860_000498"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3118986.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(29389..29619)
                     /locus_tag="VQ860_000499"
     CDS             complement(29389..29619)
                     /locus_tag="VQ860_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET3118987.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(29677..30714)
                     /locus_tag="VQ860_000500"
     CDS             complement(29677..30714)
                     /locus_tag="VQ860_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET3118988.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(30698..31186)
                     /gene="coaD"
                     /locus_tag="VQ860_000501"
     CDS             complement(30698..31186)
                     /gene="coaD"
                     /locus_tag="VQ860_000501"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET3118989.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(31176..31715)
                     /gene="rsmD"
                     /locus_tag="VQ860_000502"
     CDS             complement(31176..31715)
                     /gene="rsmD"
                     /locus_tag="VQ860_000502"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET3118990.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(31780..32772)
                     /locus_tag="VQ860_000503"
     CDS             complement(31780..32772)
                     /locus_tag="VQ860_000503"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET3118991.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(32883..33566)
                     /locus_tag="VQ860_000504"
     CDS             complement(32883..33566)
                     /locus_tag="VQ860_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET3118992.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(33622..34362)
                     /locus_tag="VQ860_000505"
     CDS             complement(33622..34362)
                     /locus_tag="VQ860_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET3118993.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            34396..34674
                     /locus_tag="VQ860_000506"
     CDS             34396..34674
                     /locus_tag="VQ860_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET3118994.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            34752..35678
                     /gene="yidC"
                     /locus_tag="VQ860_000507"
     CDS             34752..35678
                     /gene="yidC"
                     /locus_tag="VQ860_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3118995.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(35753..36547)
                     /gene="pflA"
                     /locus_tag="VQ860_000508"
     CDS             complement(35753..36547)
                     /gene="pflA"
                     /locus_tag="VQ860_000508"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET3118996.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(36673..37923)
                     /locus_tag="VQ860_000509"
     CDS             complement(36673..37923)
                     /locus_tag="VQ860_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET3118997.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(37990..38817)
                     /gene="purR"
                     /locus_tag="VQ860_000510"
     CDS             complement(37990..38817)
                     /gene="purR"
                     /locus_tag="VQ860_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET3118998.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(39084..40025)
                     /locus_tag="VQ860_000511"
     CDS             complement(39084..40025)
                     /locus_tag="VQ860_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET3118999.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(40015..41271)
                     /locus_tag="VQ860_000512"
     CDS             complement(40015..41271)
                     /locus_tag="VQ860_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET3119000.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(41273..41935)
                     /locus_tag="VQ860_000513"
     CDS             complement(41273..41935)
                     /locus_tag="VQ860_000513"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET3119001.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(41898..42554)
                     /locus_tag="VQ860_000514"
     CDS             complement(41898..42554)
                     /locus_tag="VQ860_000514"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3119002.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQSKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(42565..43443)
                     /gene="rsgA"
                     /locus_tag="VQ860_000515"
     CDS             complement(42565..43443)
                     /gene="rsgA"
                     /locus_tag="VQ860_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET3119003.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(44036..44809)
                     /locus_tag="VQ860_000516"
     CDS             complement(44036..44809)
                     /locus_tag="VQ860_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET3119004.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(45499..46371)
                     /gene="rsmA"
                     /locus_tag="VQ860_000517"
     CDS             complement(45499..46371)
                     /gene="rsmA"
                     /locus_tag="VQ860_000517"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET3119005.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
BASE COUNT        13621 a        10375 c         8593 g        13938 t
ORIGIN      
        1 gaccacaatt actcaatacc gaatacccct gaatggtttc tttttcatgc accaatatat
       61 tataataatc ttcatccaat aataaggctg ataaactagc atcttggtca aaatgtaagg
      121 gaatttctcg accgtccttc tttaatggat attctggtaa gatactaaat agttcaatca
      181 tagaaggaaa ctcagaatta gttgttgtaa atcgaaaaag ctgcgctttc tcatctttct
      241 gacttccttg atactctccc aattctaaaa aatgattcaa ggtagtataa aattccttat
      301 tttttacttc atcaatgatg accatatcat aatcttttgt tgtgcgactt ttaaatcctt
      361 gcgaatccaa tacgatagag gtagcagttc ccccaatcag aacataatag ttctgaaaat
      421 ccgcaaacat ttcttgaaaa ataactttcg tattagctgg catcatcttc tcccagatac
      481 tgtaatatca tattttctag tgcttcactc tcttcctcta tacgtgggtc atcatcatct
      541 tttaaggtca aataaagaga aatcggatct acaaattgtt tatcatgatt atttttaaaa
      601 tcattccaaa actcagatac aaaaggacga tatttccata tctctagcat ctttcatttt
      661 aaaacatgct gagaaagtgg caaggataac tgattgaatt ttctctgcca tatgacatag
      721 ctagtatttt catccgtttc agctaaaaaa gttgaatgcg acaaagcata agcaccacca
      781 tatagaaggt tagaaacaga ttttatctgc tttatatcgc catctggcaa taaaaaggca
      841 atccacgtta attgttcgct aggtattaat tccttaggga cttcagtatc attcgcattc
      901 agtactagtc ccaatgtagg gaagaagagg tttcccttaa agtctacaaa cggaactcta
      961 gcttgaagta attgcttttt ttcaccgtct gataacttcg aaaacaccaa aacaacatcc
     1021 atattggctt tatcacccat agtgcgagcc tgagtaacaa atgaactcaa actccccctt
     1081 ctcttttctt taatcaataa aaatgattcc ttatgaaaag tcatttgagt atactcaaac
     1141 ttttttacaa aactgattgg taaagtcaaa gtcagttcct caatactgac atcaacataa
     1201 aaggattgaa aaattgacat tatctttttg acattcatgt tttttcctta ttctatcatt
     1261 tttattatat tttatcattc ggtataataa aatataagtt ttttgataaa ataaccaaaa
     1321 actactcgct atcccctctc acattaccct acatatcgtt tgacatgcga ctgatagttc
     1381 aggaaaactt caaggagaac ttttctctca tccactatgc aggacttact atttcacttc
     1441 tactcctata ggctcaattt gacatttttc tttttcgaat tgctcatatg cctcctgaat
     1501 agtgagttcg atttatccaa atttattttt gtctattttg atgaatactt ccacgaagaa
     1561 tgaatttgca ccaattttcc ttctcttttt aagcatatta ttccagatat gattgccctc
     1621 ttgttcagta ataaattacg ctttaaacgc ttcaatcagt atatctcctg ttgtcatatg
     1681 ttctaaagaa aattcttcta catatggttt aacatctctt aggttattac ttcctaatat
     1741 cccattatgc tttttcgcta aggaaataga tgccccttct cctttaccaa taatcttgtt
     1801 actatcatga tttcttgtta aatctctata taatgcgtat tcttcagttc caatgtctat
     1861 gctcacaatc tcagctgaac ccttagctac caactgatct atcctagatt ttaaatgggg
     1921 aattgtaggt atattgattt catcatacac ctcttgtgga ataacaattt tacccaaata
     1981 gagcttttct aaaagatgtt caatgccaac ccataaaaat actgaaatac aatctgcatc
     2041 aataaataca cgactagtca aacgacaact cccccctctt catctagccc atatacaata
     2101 tcatatctga aagcatctag taacagttcc tcatacttcc cttgcgaaat tctgttattt
     2161 tctaaaagtt gttcagttga attaatatat tatcctaatg ccatttcttt tttactttct
     2221 gacaaaggac gatataaact tgtatcatag cctaatcttg aagctgtctc tataacacta
     2281 atatccatat ttttaatttc ttctgcatca aggtatccat cattcctcaa tctatataac
     2341 atagctttat gactgatacc ataaaactga cccaatttta taatatcttc tacttcaaga
     2401 tgagttctat tggcattttc tctgatttcc tcaaccatcc tatacagtga agatgggaaa
     2461 attaaaaaat aagaagcaaa ctgatccgct tttctttcag tttcatctcc ttcaccaatc
     2521 aagataagac tgactgaact cttcttcacc tcatcataat aaagatgata cagtccatgt
     2581 gctaaagaaa atctttacct ttctaatggc atgtctgaat tgactgcaat gagactgaac
     2641 tgagttcctt tataacagac tccgctaata ttctttccga gtccataaaa taccagcgtc
     2701 aaattttcta tcttttgtac caatttaaaa atatctatcg gcgattcacc atcagctccc
     2761 aacttttttc taagatttga agctttatta cttaaatcca ttcgtgatat tcctttcacc
     2821 tttttccatt ttggcaatca tgctttgatt caaagacaaa tactcagcaa tcttatcttg
     2881 agtaagattt gaagatattc taagttcttt tattcttttt ccaacatcac atacatttat
     2941 cacatacatt tatcatattc atacacctct cataaaaaga atagcacact cttgtcataa
     3001 ttttttaaat aaaaaaatta tgacaaaaca aggaagcaat ttattgatgc tgcttaaaaa
     3061 tctaaaattg atgagttcct atcaaaaatc gtatcttcaa cctcaaaaca gtacttaaag
     3121 ctatccgact cggtttacat tgtcaaattt agattttatt tgagcataac tttctagttt
     3181 gctttctgat ttttgtttaa tatagtagca aacattgaag gaaatatctc cacaaaaaaa
     3241 cgcatactat taagcttttt caagacctaa taatatgcgc tgttctgatt tgaaagacat
     3301 tccattatta ttttactgta atcaagccat ctggctctac tgtgaattct ggcttgtctg
     3361 ccagtgttcc gtctggtttg aggtagtacc agcctgttcc gtccgctgac tggataaagg
     3421 catttgatac catggcgcct tctttagcgt ctaagtagta ccaagtgtcc ttgtacttga
     3481 cccagcctgt cttcatggca ccttcttcgt tgaaatagta ccacttatca gcgattttct
     3541 tccagcctgt agccatttcg cctgagttgt cgaaccagta ccagttgccg tctgtgtgct
     3601 tcctccagcg gtctgcaagc atatagcctg aactgtcaaa gtagtaccaa gtgccattga
     3661 ttttctcaaa cttgtctttt ggataagagc cgtctgaatg tacgtaccag tagccagtgt
     3721 cattcttctg ccagcctgtt tcaatcgtca agccgttctc aatatcatac ttaaactgct
     3781 cacggctaat gccccatttt gccaagtaag ggtatggatc cacatggtct gagtggttgt
     3841 ttggttggtt attcgtgcaa tactcgtgcg ttttaattcc agctaaactc cctgtatcaa
     3901 gcgttttcgg caaacctgct tcatctgcta gattgcgtaa gagttcgata taaaggcggt
     3961 aatccgtcat gaactcttct ttagttgaat ggctttcaat cagttcaacc gctgcatagg
     4021 tctcagcatt ccaaccgccc ccaacgtccc aggcaccatt atcaacaggt cctacctgca
     4081 tgatgcaacc gttcccaaca atgtgcgaga aaaaacctaa ttctgggtct ttccgccagt
     4141 gataatccgc ttcattctgt acggttgaat gcggattccc agttgagtgt gcgtgtactt
     4201 gcctatatgg ttgcacgccg acttgaggca aatctgttct taatttactc acattaattt
     4261 ccatattcta ctccttatca attaaaacaa ctcatttttt acaatccaga accagaaact
     4321 cctttatttc taccttacaa agaagacaat cttagtcacg attaggcttg tagatagaac
     4381 ctcaaaacgc actattttga cactgtaaat aggactgaca aggtctgcat tctatctaca
     4441 ataacacccc agactaaaaa gcttttcaaa agtatatttt tacagtctct atatgtcctt
     4501 ttcataaata ctatacttta ttatatcata taaaagaagt caaaagtctg ttaaactatt
     4561 ttcaacacca aactaaagaa gagaacacaa gttttttcga tgttcactag aggaaatgga
     4621 ttttattcag taaatccaac taggattgca ctttggttgc caaaattgcc tttccttctt
     4681 ttatcaaggg atgacggaat agtgagaagt acagttgaac tgtcatggca acccagataa
     4741 gaggttcaca aaggataaca cccttatatc ctgcccaagg aataatcaaa accacaaaaa
     4801 cgatttttcc gattagttca ataaagctag aaactagagg aaggatcttc tgccccaagc
     4861 cctgcaagca attgcgataa atcaacaaga ggctcaaaat gggataaaag gctgaactga
     4921 tttgcagata gagacttcca ttttctatca agtaaccatc tgtcgaacta gccaagaagg
     4981 aaaccaaggc tggactggca aaaaagagga aaatacaaac aaaaactgcc caggatatac
     5041 ttaaacgact gccgattcga agaccttgaa caatgcggtc aggtcgctta gctcctagat
     5101 tctgagaagc aaaggtcgtc attgatgcag aaatagcggt cataggaaga agggcaaagg
     5161 tcataatgcg tcgagctgcc gtctgggcac taataatcac tgcaccaaat gtattaacag
     5221 aaaactgtaa aatcacactg ccgatagata caattgaact catcaagccc atagccaaac
     5281 cttgctccaa gagatccgcg tacaagcttt tgtcccattt gaaatgttta aaccgtggca
     5341 agagttctgg cacactttta cgaatataat aaaagcagag aaccgctgat aaaccttgcg
     5401 aaataatggt agcaagtcct gcggattgaa ctcccagatg caattgcgta ataaaataga
     5461 gatccagaac cacattaacc aaggcagaga aaatcagaaa tcccagggct gctagactgt
     5521 caccaataga ccgcaacaag cctgcaaaaa gattataagc aaagctgaca cctacacagg
     5581 tcacaatcat agaaatatat tgataagatt gaggaagaat ttctgcagga gtatctaagt
     5641 attgcaagag aggatacaag ccaagaaagc ccagcaacat aactagaatg ctcaaaagag
     5701 cacctaaaat ccaggtggct gctactgctt ccttgatttt agtgaaattc cgagccccat
     5761 aataacgagc aatgacaatc cccatgccat tgccaacacc aagtgtaaaa cctacaatca
     5821 ggtcaaaaat cgctgtcgtc gctcctactg cagccaagga ttcttgacca agaaatcgtc
     5881 caacaatcaa gacatcagca gtgttataga gctgttgaaa aatatttgat agcaagattg
     5941 gaaaggtgaa gcttaagagc gagggaagaa tcgaaccatg tatcaggtcc actgttcgtt
     6001 ttttattcat aaagctatta tatcagcttt ccagaggagc gacaagaaac agcaaactta
     6061 tatatagcgg aatgaaataa ggacagtcaa atcgattttt aacaatgttt tagaaataga
     6121 tgtgtactat tctagtttcg atctattata gttggttgag tttggaatag tacgctgtag
     6181 ctgctaaaac atttctagaa attaatttga ctttcctaat aaagttgttc atatcttatt
     6241 tcaagctact atatataatc taaaaacttg aatcaaaaat cgaaaaagta gcggattttt
     6301 ccactgcttt aacagcttat tcttcaattt cgatttcaag ttcatcgcct aagtcaagcg
     6361 taacttcttc attcactgct tcttctttct ttggctcatc ttttttgttt tcagtatctt
     6421 gttctgaaac ttcttctcca tcaatcaagc caaatttaga acggacttgc ttatcaattt
     6481 catcaaagat ttctgggtgc tctgccaagt atttcttagc attctcagaa ccttgcccaa
     6541 ttttttcatc tttgtaagaa taccaagccc ctgctttttt gataatatcc aaatcgcttg
     6601 caatcttcaa aagctcacca gtcttagaaa ttccttctcc gtacataatt tcaactacgg
     6661 cttccttaaa cggtggagct accttatttt ttacaacctt aatcttagtt tctttaccga
     6721 cattggtttc tttttggtca ccagttccct taatttgtgt attaccacga acatccaagc
     6781 ggactgaagc atagaatttc aaagcacgtc cgcccggtgt tgtttctgga tttccaaaca
     6841 tcactccaac tttttcacgc aattggttga taaaaatggc aattgttttg gttttattga
     6901 tagaggcgcc aagtttacgc atggcctggc tcatcatacg agcctgcaaa ccaacatggc
     6961 tatctccgat atctccatca atttccgcac gaggaacaag ggcagcaact gagtcgacta
     7021 cgacaagatc aactgcacct gagtcaatca attttcccgc aatttcaaga ccttgctctc
     7081 ctgagtctgg ttgagacaag agcaattcgt caatattgac accaagggcc gcagcataag
     7141 ctggatcaag ggcatgttcc gcatcgataa aggcagcaat cccaccttct ttttgcgctt
     7201 gtgcaactgc atgaagggca accgttgtct taccagatga ctctgggcca tagatttcga
     7261 tgatacgtcc cttaggataa ccacctgagc caagggcaat gtcaagagct aaagaacctg
     7321 agctcatcac ttgcaccttt tgctccgcac gttcacccaa acgcatgatt gatcctttac
     7381 caaagtcttt ctcaatcaat ttaagagcgt cattcaaggc cttttcacgt tctgccccaa
     7441 atttttttga aatttcttct aatttttttg gttttttcgc cattctattc tcctacattc
     7501 taatgatcct cagacctatc tactattata tcaaaagtta gtcacttaat aaagccttgc
     7561 gaactaggtt aaaggcatgc ataaccgcaa tatgacgtac atctgctcgg cttctgcctc
     7621 caatattaac cttgataacc tcagttcctt gctcttgcgc caagcctatg aagactgtcc
     7681 caactgggtg tccttctagg ctatctggtc ctgccactcc ggtcaaacta attccaaaat
     7741 cagactgggt cttgcttcgt gcctgctcag ccatcttctg agctgtaaat tcagacacca
     7801 caccatgttc ttccaaattc ttggcaggaa tatccaacat ccttgatttt tcctccaagc
     7861 tataggtcac aaaaccaccc ttaaatatac ttgaaactcc agaaaaattc gccacggtag
     7921 cttggaaaag acctgccgtc aaactctctg cagccgcgat ggttttccct tgccttttca
     7981 gttcttctac cacaatgctg gctaaactag tttcttcccc ataaccatag caaaagtctc
     8041 gtaaagaaat tccttcgaaa gtctggcagt ccaagatttg attttccaag atatccagcg
     8101 cttgattcgc ctcttcttga ctgctagcct ttgttgacag acgtagagtg acttctcctg
     8161 tcttggcata aggggccaag gtaggatcga tctgattatc aattaaatca gccaaaatcg
     8221 taaccagctg gctctcgcca atcccaaaga aacgaagaac tcgggaatac agcttgctcc
     8281 ctgtcatcaa cttgggtaga agttggttta agaccatggg tttcaattca cttggcggac
     8341 ctggaaggac gacataggtc actccgtcta cttctaattt tcctccaaca gccagtcctg
     8401 tttcgtttgg cagtggaatc gctccttcta caatttgagc ttgtctttcg ttattcggtg
     8461 ttcgggcata gtctggtcgc agggcaaaaa agatatccaa cttctcctga gcctgaggat
     8521 caaagactaa tgctttccct aaaaatttag ctagggtttg tttggttagg tcgtcctcag
     8581 ttggccccaa accgcctgtc aaaatcacca gactgctacg ttgactggca atctcaagca
     8641 aagacaagag acgaacttca ttgtctccta cagccgtctg aaaatataca tctaccccaa
     8701 tctcagctag tttttccgac aaaaactggg cattggtgtt gacaatctgt cctgtcaaaa
     8761 tctctgttcc aacagcaatg atttctgctt tcatgtttcc tcctacctat ctattcgtat
     8821 ttttttgaaa aaatcgcagg aattttccta cgattgattt ttttatttgt atcaaaagtt
     8881 aattatcttc atcaccaaca ggtgctctgc caaataaatc ttcaaataaa accgcattgg
     8941 tttcaagctg agtaacttct tcttgtccca aagaacgtcg gagtatattt tgcatttcca
     9001 acatatgtgc tctcgaaaca atctggtaag aaacaccttg aagtatctct ccttcaccct
     9061 gcaactgctg agtttcaatg gttttaaatg aatctttata gcctagcaag ttagggatac
     9121 tttttgcaga caaatcaata ttggtctgca tattgtcact caaagctttt agaatctctt
     9181 gataatgacc aatgctattt aaactgagag ctttttccat gactttttga ataacttcac
     9241 gttgacgttt ttgacgacca taatccccct caggatcttg gtaacgcatt cgtgcataga
     9301 ctagggcttc ttctccccca atatgttgct ccccaacacc gatagaaatg gtattaaatt
     9361 cttcttggtc actgatagaa attgggaaac ctaggatatt attgactgta atacctccta
     9421 ctgcatccac taatttttgc aaccctctca tattgaccat cacatagcga tcaatatgga
     9481 tattcatcat tttttgaatg gtttctatag caagctctgc tccaccatct gcatatgctg
     9541 agttcagttt cgcttcatga gcctgaccat tccctgattc aatgcgcgtc agaatatccc
     9601 gctctaaact catcattgtt gtttttttcg ttttaggatt cactgtcatc aagatcatgc
     9661 tatcacttct accgacccaa gtttcagttc gttcaacatt tccggtgtcc actcccatta
     9721 acagaatggt tagaggttca gtcgcttcaa taaccttggt ttcttcgccg atttttttat
     9781 aggttttagc taaggtttct gtcccttgtt gataaatagt ataagcaaaa acacctactc
     9841 ctactacagt tacagaaagt aaagctagca ccattccaat aattttttta accatatttc
     9901 tactaaccta tcagtttacc catcaagtaa acatcgataa atttcccttc ttctatatat
     9961 gccccacgct cttggctacc ttcaatgaca aagccatgct tttgataaag atggactgct
    10021 gcttgattac gagtttggac agtcagttgg agacgacgca gaatgccact tgcttgtgcc
    10081 cactctatcg cttcttctag caacaaactt cccaagccat tattccaata tctttttcca
    10141 atcacaatga agagatctcc aatatgacgg actctcttac gctgatcagc tgtaatattt
    10201 acaataccag taattttgcc atttaagaat gcaagtaagg ttatctgatt gtccgaacta
    10261 gcttgcttgt tgaggaatat ttccatctcc tcactagtca agagaatacc atctccgtct
    10321 aggctggtaa agtctgtctc caaactcaca cgatttaaaa aggccactaa ttcagctgca
    10381 tctttgggct ctgcttccct aatgagcaat tcatactcca tattgaagct cctctgacaa
    10441 tttctcagca cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg cttcttttag
    10501 aatttccaat tctaaataag catctggcaa ggcatctcct aagagatttc cccactcaat
    10561 aacagtcacg ccgccaccaa agataaactc atccaagtcg atagaatcag catctccttc
    10621 aatacgataa acatctaggt gataaagtgg aagtcgacct tcatactctc tcacgatagt
    10681 ataggtagga cttttaatca tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa
    10741 ggtcgtttta cctgcaccca gttctccaat taagattaaa acatcattct ttgctaatag
    10801 atggcccaaa cgctccccta aggcttgcaa ctcttcttca ttttttatgt acatactctt
    10861 attataccaa aaacttttct tttgtgtcta ttttcctact aaacttatca tcataacatc
    10921 cataaaaaac aggctttctc taaaagaaaa tgagcgtaac aatgaccaat acaagatctc
    10981 ggaaaatatg accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg
    11041 caaaaaacaa gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta
    11101 agaaaagaag tgttgctaaa atagtcacca acactgtctt ttttctgtcc agcatagcaa
    11161 gaaaatcgcg cacgtatttt ttcaagggta aaaaaatcag caaatctagc ccaaatagga
    11221 aaaagaagga tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca
    11281 agttatctga caaaacaaga acagctccta acaaattaat taagagtaac atactgtaaa
    11341 aaagcttcac cgacttctta ctggctagga cactatggac ttcttgctta cgagtataaa
    11401 gataatttac tccagcacag attcctgaaa cgaaaaccat gcttccgatg aaaaaagctg
    11461 tactttgttt aaaggacaag atgcattcct tccataggaa acagctactc aaactgattt
    11521 gaattaaagc taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc
    11581 aatcattata ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag
    11641 acgctaaaca aacactagag actaatactc aatgaaaatc aaagagcaaa ctaggtagct
    11701 agccacaggt tgctcaaaac actgttttga gattgcagat agagctgacg tggtttgaag
    11761 agatttacga agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg
    11821 tctcgcacct cacggagcga gacggactca gagtcacata attataaggc tgatagtatt
    11881 aatctaacta tcagccttac aggttattta acgtttcaga aaaactataa tgtcaagatt
    11941 aactaaacag tatctagttc cttcaaataa ttttctatct tcatcaacat taaaggattg
    12001 ttataaatct tacataactc tcttgcttct atataataat ttttgacttg ttctctgtct
    12061 agaaatttgg ctccagcatt tcctacaaga ataagtagag gagccaattg gtagcttgtc
    12121 tgtctttgtt tacagagttc aatcgtttca agagcttctt ggatggcttc attatatttt
    12181 tcctttgata ctaggtagtg agcgtagttg taacgaactc tgatgtagcc aaataaaaac
    12241 tcttgatggt ccaaattttt tgtctgatac aactctatta aatgagagta gtttgcctca
    12301 tattcttgtt cacgacccac taaggaatag aaattagata gagtattcaa cgcctttaaa
    12361 taaatcagag tatttgaaga gacttttaat aatatatttt ccaatgaaga aattgcctca
    12421 cacttactgt catattgata gaagtcaata atagctttaa tccattcaag gtaagttcgg
    12481 tcttctagtg ttagaaaagt acttcgttca atctctattc tataaatata ttccaaatcg
    12541 tcataatttc tatcgtctaa tagtcgagca gacaattgct tgaaattaga gaggttagat
    12601 ttaatttcaa tttgttcatt aaaaaaataa tctaatggta cttcaagtcg ttgagagagt
    12661 ttgaacaaaa ggtctgcgga gggaatgaaa tgccctctct caattttact aatctgactt
    12721 tgttcacaaa ttccttctgc aagagtttgt tgggagagtc tcaactcttt tcttttcaat
    12781 ctgaatttct ctgcgagtgt attcattaaa gataataaac cttcctattt gcttaattgc
    12841 attataaaat ttttagttca aaatagcaag ttaaaagaat aaataattct ttatggtaat
    12901 aaactaaaaa aagtcaaaaa ttacataaaa atgcttgacc gaataatata tatatattaa
    12961 aataaaaaca aggaaaaaga aaagggtttc acgaatgaag aaaaatcgtg gaattcaaaa
    13021 attagctata ttagtattac taggtgtttt tatgcttagt aacacaattc cttaccaaca
    13081 gtttattcag aagaatagac aattggagat tcgagtccaa tcacaaaaga agtccaatgg
    13141 tcttgatgtt gggaaggctg attgatttcg tattacttta aaattcaact atttagagaa
    13201 aggtattctg atgagagctt gtaacaatac cagatagata ttagtaagct tgttagttta
    13261 tagagggcag gggtatttct gccctctgtt ttagaataag gaatgcacta tgaaaaaatt
    13321 atttatactc atatccaacc tgcttgctag tttgttcttt gtttgggtat ttaccatttg
    13381 gactgataca tatgtctcct attattaccc caacgttgtt gtacatgatt cttcccctga
    13441 aacaactttt cagcatgttg ctacacgctt ggaaaaacta gcagaagaaa cagatagctt
    13501 tattgcgatt caacaccaag attctaactc agaaggtact acagtttttt cttatacgac
    13561 ctttggggac ggaaagttgc ctgatgggct tcaggaaaaa aaactagaag atgctcaaag
    13621 tagtagtgtt gaaacaaact attttgtatt cgatggacac ctagatattc acttgctaag
    13681 ggaggagcta agtcaacttg gcttgactaa catgaacctg acaattccat ctaaactatc
    13741 tacgttaatg gctatcttta gtaacggatt tcagttaatc agtctattga ttttcatctt
    13801 aacctttgta gcactgactt taattagtca aattagccaa ttacggtcgt cgggcattcg
    13861 cctcatttca ggagagaaac ggtggtccat tttccttaga ccagttggtg aggatttgaa
    13921 agggatagct gttggtttca gtttagctgg cgtgctcgcc attcttatgc aaaaaattct
    13981 gtcgcttcca acgcaatccc taatgaccat aggagcaggc ttgctcagtt ataatctcat
    14041 cttgttgtcg atctccctgt ttttcgctca actcttcgca gttgggataa aaaagataca
    14101 cctgatgcag attataaaag ggcaagtgcc tgtcagagga atcattagtt tgattttaat
    14161 cggtcaacta ttagcgatta ttattgtaac gctgggaata gggagtagct taaagtattc
    14221 ccaagcctgg caacagcatc ggattggaca agaggcttgg agtcaggaaa ggcaactgat
    14281 taccctatca atcagccgtg aaggaacgag tcctggtttt gatgaacaag ctcaaaggaa
    14341 actcagaact tggtatcaat tgatggatct ggctgtttca gaacaaaagg ctttcttatc
    14401 tagacaccag ttaattgacc gtactttgca aaatggcatg gcttcctcca aaaacttgat
    14461 aacctctaca gaatggcacg attacaaccc gaatggcaat gtccttatcg tcacaccgca
    14521 atacttggag cgtcaaaaca ttcctgtaga tacaactatt gagcaaaaga tgaatcacct
    14581 ttatgtaggg gagtttgtct tattgctgcc tgaacacctc cgttcagagg aagaacatta
    14641 taaatctgtt tttgaagacg acttaaccag tcgcatgtct agtcaagatg aacgacagca
    14701 aatgactgct acggtaggtt atttagaatc aggtcaggat cgttttgtgt ataatacgac
    14761 ccctatttct taccagcagt ttttgaaaga tccaatcatc attgttataa caccccaatc
    14821 aactggtcca cagtccattt tgttttggat agacgcagta cagaactacg ttctctttaa
    14881 tcaattgtct gatgcccagg agcttatcca gagacaaggc attgaaaatt gggtctcaga
    14941 aatgcaaaca ggttaccaca actacatcac attattggat aatattcaga gggaacgttg
    15001 ggtaatgcta gcaggagctg ggcttgggat tgcaacttca atcttgttgt ttaacactat
    15061 gaataggctc tactttgaag aatttagacg tgccattttt atcaaacgca ttgcaggtct
    15121 caggttctta gaaatccatc gcacttatct ctttgctcaa ctgggtgtgt ttttactggg
    15181 atttgttgcg agtgtatttc ttcaggtaga gataggagtt gctttcttag tcttgttact
    15241 ctttactggt ctatctcttt tacagttaca tgtccaaatg cagaaagaaa acaagatgtc
    15301 catgcttgtt ttgaagggag gttaatatga ttgaacttaa acaggtgagt aaatcttttg
    15361 gagaacgaga gttattttcg aatctttcaa tgacatttga ggctggaaaa gtctatgcct
    15421 taattggttc aagtggtagc ggaaaaacaa ccttgatgaa catgattggg aaattagaac
    15481 cttatgatgg gacgattttt taccgaggta aagacttggc caattataaa tcgagtgatt
    15541 ttttccgtca cgaattgggc tacctcttcc agaactttgg cttaattgaa aaccaaagta
    15601 ttgaagaaaa ccttaagcta ggtctcattg gtcaaaagtt gagtcggtcg gaacagcggt
    15661 tgaggcagaa gcaggcttta gaacaggtcg gcctgactta tcttgaccta gataagcgca
    15721 tctttgagtt atcgggcgga gaatcgcaac gggttgcctt ggcaaaagtt atcttaaaga
    15781 atccaccctt tattctggca gatgagccaa cagcttcaat agacccagca acttctcagt
    15841 tgattatgga gattttgcta tctcttcgag atgataatag gctaatcatt atcgcaacac
    15901 ataatccagc aatttgggag atggctgatg aagtgttcac gatggatcgt ctgaaataaa
    15961 aatccttgtt tttaattgca cgatgagtta ctgaaatatt atcatgaatc aataattgga
    16021 gttaatttag aattgtactt tattaatatt gaggtaactt tttcttgata aaggaagaaa
    16081 tagtggagag gaagttagaa tgaaaaaatt cgacaattat attgttgaga agccttgcga
    16141 ttctaattca gataaactgc aaaaaatctt aataattgaa aatttggtag atgatatttt
    16201 gcaatttcct ctcagaatca ataatagtgt aggagagatt ttcctcctac aaccgtttca
    16261 aaagaaaact atctttattc catgttattt tgaggaagat attgtgaaag tcaaagatga
    16321 tgataaagtt gagtggaatt tgttagaatt tcaaaaattt agagcatttt tggcttagta
    16381 atctgtgttg aaggctcaaa acctatggta aaaaagtcgc tttgaaaacg tattgcctcc
    16441 aaagatttag ttaaataatg atttaacaca aaaagaaatt attgaagttc tggaaagatg
    16501 ttgtttcagt attgagaaaa ggtgggaaaa acttgcgatt ttcacagaga aaggaagaaa
    16561 aagtatagaa atatagtcaa ttgaaacaag aacaggacaa aagaaccttt tgtgccatat
    16621 ttttctcctt tcgctttaca attggcttga acacctttat tgtatcgcgt ttggagtttt
    16681 tttggtataa ccttcgacgc gcacccgcat agcgggtgtt tttttgtctc gcacctaacg
    16741 gagcgagacg aactaatagt cacttaatca aaaaacgcac catatcaaaa actaaaaagt
    16801 ttgatatcat gcgtcatgtc ttaaactaat tgactatact ttctattcaa atgagctttt
    16861 aaccaattga ttgagccaat ccactcttaa aaccaaagag caatttctcg cttagctgac
    16921 tcttctgaat ctgaaccatg tacaacattt tggataacct cattttctcc agcagctttt
    16981 gcaaaatcac ctcgaatagt gcctggtaaa gcttcttctg gacgagttgc acccatcatg
    17041 gtccgccaag tttcgattac tttgggacca gaaatgacac ccacaagaac tggacctgaa
    17101 gtcatgaatt cacgaatcgg tgggtaaaaa ctctgaccaa ccaagtcctg atagtgctgg
    17161 tcaatcaact cttctgaaac ttgtgaacga aactccaatt tttcgattgt aaatccacgt
    17221 tgttcgatgc gctttaacac ttcacccact agccctcttt ttacaccatc tggtttgatg
    17281 ataaagaatg tttgttccat acccgtctcc tttgtcagct tctttctttt attttaccac
    17341 atttcgtgga aaaatggaga aagttttcag aatagagaat gagagaaccc gagggttctc
    17401 tcattctcta ttattctact gtttcttcca cagtttcaac ggcagtatcc acaactactt
    17461 ctgttgtttc ttcatttcct tcttcctcta ctggaggatt aaggtattct tcttcgttga
    17521 cagcatatgg ttcaaggtta cggtaacggg ccataccagt accagctggg atgatcttac
    17581 cgatgataac attttcttta agtccaagga gatggtcttt cttaccacgg atagctgcgt
    17641 cagtaaggac acgagttgtt tcctggaagg aagccgctga caagaaactg tttgtttcaa
    17701 gtgaggcttt ggtaattccc ataaggactg ggcgacctgt cgctggaact ccacctgcga
    17761 taaggacatc tttgttggca tctgtaaagt cattgatatc catgagggta cccatgagaa
    17821 gatctgtatc acctggatcc atgacacgga ctttacggat catttgacga accattacct
    17881 cgatgtgttt gtcaccgatt tctacccctt ggctacggta aactttttgt acttcaccga
    17941 gaaggtacgt ttcaactgac aagacatcac gaactgcaag gagacgtttt ggttggatag
    18001 aaccttctgt cagagcagca ccacgcgcta cttggccccc aacttcgaca cgcatacgag
    18061 ctgtaaatgg aacgacatat tcaccttcgc cagtttcacc cttaacaaag actttcttgg
    18121 tacgagttga tgcatcttct tcgatagcag taacttgtcc tttaacctct gtgataaccg
    18181 cttccccttt aggattgcgg gcttcaaaga tttcttggac acgaggaaga ccctgagtga
    18241 tatcggtatt tgaggcaacc ccacctgtgt ggaaggtacg cattgtaagc tgtgtaccag
    18301 gttccccgat agattgggca gcaatggtac caactgcttc accaacttca accgcatcac
    18361 cagtcgccaa gttgataccg taacagtgac ggcagacacc gtgacgagtg ttacatgtaa
    18421 atacagaacg gatagtcact tcttccacac cagcattgac aatttcacgc gccttgtctt
    18481 ctgtaatcaa ttcatttgga ccaataatca ctgcaccagt ttctggatgt ttaacagttt
    18541 tcttagtgta acgaccgttg agacgctctt cgagagactc gatcatctct tttccttctg
    18601 cgatagaacg gatcaagaga ccacggtcag ttccacagtc gtcctcacgg atgataacgt
    18661 cttgggcaac gtcgaccaaa cgacgagtca agtaacctga gtcggctgtc ttaagggccg
    18721 tatcggtcat acctttacga gcaccgtgag ttgagaagaa catttccaat accgacaaac
    18781 cttcgcggaa gtttgaaagg attggcaatt ccatgatacg tccattcgga gcagccatca
    18841 gaccacgcat accggcaagc tgtgagaagt ttgagatgtt accacgggct ccagagtcca
    18901 tcatcataac gattgggttc ttaggatctt ggttagcaat caagcgtttc tcaagttttt
    18961 cacgggcagc acgccattca gctgtaacag cattgtaacg ctcgtcgtct gtgatcatac
    19021 cacgacggaa ttgtttggtg atttgttcga cacgtttgtg tgattcttca atgatttcag
    19081 tcttgtcatc aacgactggg atatcggcaa tacccactgt caatcctgca agagttgagt
    19141 ggtggtaacc gaggttcttc atgcggtcaa gtagggcaga agtttctgtc gtacggaaac
    19201 gtttgaagat ttcagcgatg atatttccaa ggtttttctt cttgaatgga gggttgagct
    19261 caagattgct gatagcttcc ttgatatctc caccaagtgg caagaagtat ttagctggaa
    19321 caccttctgt caagttggca ttgtttggtt cttgcaagta tggtagcccc tctggcatga
    19381 tatcgttgaa gagaatttta ccaactgttg taagcaagac cttatgtctt tgctcttctg
    19441 tccaaggctt gttgaggctg tctgttgcga taccaacacg tgagtggagg tgaacataac
    19501 cattgcggta agccataacc gcttcgtcac ggtctttgaa gaccattcct tcaccttcgc
    19561 gaccagcttc ttccatggtc aagtagtagt tacccaaaac catgtcctga gatggagtaa
    19621 ctaccggttt cccatctttc gggttcaaga tgtgctcagc agctagcatg aggatacgag
    19681 cttctgcttg tgcttcttct gaaagtggta cgtggatggc catttggtcc ccgtcaaagt
    19741 cggcattgta ggcttcacag acaagtgggt gcaagcgaag agccttacca tcaattaaga
    19801 ctggctcgaa ggcttggata cccaaacggt gaagggtcgg tgcgcggttc aaaagcactg
    19861 ggtgttcttt aatcacttct tcaaggatat cccagatacg ctcatctccg cgttccacca
    19921 agcgtttagc tgctttgacg ttttgcacga tatcacgggc aacgatttca cgcatgacaa
    19981 atggtttaaa gagttcaatc gccatttcac gtggcacacc acattggtac atcttaagag
    20041 ttggaccaac ggcgataacg gaacgtcctg agaagtcaac acgtttaccg agcaagtttt
    20101 gacggaagcg tccttgttta cctttaagca tgtggctcaa tgatttcaat ggacggctac
    20161 ctggtcctgt gattggacga ccacgacgac cattgtcaat caaagcgtca actgcttctt
    20221 gaagcatacg tttctcattt tgaacgatga tacctggtgc atttaactca agcaaacgag
    20281 ccaaacggtt gttacggttg ataacacggc ggtaaaggtc attcaagtca gatgaggcaa
    20341 aacggccacc atccaactgc aacattggac gaagatctgg tgggataacc ggaaggatgt
    20401 taagaatcat ccattcaggt ttgtttccag acttgtaaaa ggcatccaaa acatccaaac
    20461 gacggatggc tttgacacgt ttttgtccag tagctgtttt caattcttct ttgagttcag
    20521 caatttcttt ttcaagatct acttgcttca aaaggtcttg gatggcttcc gcacccatct
    20581 tggcaacaaa tgaaccataa ccatattcgc gcaagcgctc tcggtattcg cgctctgtca
    20641 tgatagactt gtgctcaagt ggtgtatcct taggatcaat caccacataa gccgcaaagt
    20701 agataacttc ctcgagggca cgagggctca tatcaagggt caagcccata cggcttggaa
    20761 tccccttgaa gtaccagatg tgagatacag gagctttcaa ttcgatatgt cccatacgct
    20821 cacgacgaac tttcgtacgc gttacttcaa ccccacagcg gtcacaaaca attcctctgt
    20881 aacgaatgcg tttgtactta ccacaagcac attcccagtc ttttgtagga ccaaagatca
    20941 cttcatcaaa gagtccttca cgttctggtt tcaaggtacg ataattgatt gtttcaggtt
    21001 ttttgacttc tccataagac catgaacgga ctttacttgg agaagctagg gtgatttgca
    21061 tacttttaaa acgatttaca tcaaccacta tttcttccct ttctattcta agtgaactgc
    21121 ttattcttgt tcagcagctt cttctgttgc ttccgctttt gttgctttct cagcttcttc
    21181 agcttcaaag gctgctttag cctcttgggc tgctttttcg cgggcttttt caaggtcatc
    21241 tacgtggatg acatcttcgt ccattccttc atccaagtcg cgaagttcca cttcttggtc
    21301 atcttcgtct aggacacgca tgtcaagacc aagagattgc aattctttga caagaactcg
    21361 gaaggattct ggaacacctg gttttggaat tggtttgcct tttgtaatag cttcataggc
    21421 tttcaaacgt ccgttgatat cgtccgactt gtaagtcaag atttcttgaa ggacatttga
    21481 cgcaccgtag gcttcaagag cccaaacctc catctcaccg aaacgttgtc caccaaactg
    21541 agccttacct ccgagtggtt gttgggtaac agttgagtat ggtccgactg aacgcgcgtg
    21601 caatttatca tcaaccatgt ggtggagttt gatcatgtac atgactccga cagaaacacg
    21661 gttatcaaac ggttcaccag tacgtccatc gtaaaggatc gttttggcat cgctatccat
    21721 acctgcttct ttaacagttg accaaagatc ttcagaactt gctccatcaa agactggtgt
    21781 cgcgatgtga ataccaagag tacgagctgc cataccaagg tgaagctcca taacctgacc
    21841 gatattcata cgtgatggta ccccaagtgg gttcaacatg atgtcgactg gagttccgtc
    21901 tggaaggtaa ggcatgtctt ctacaggaac gatacgagag acaacccctt tgtttccgtg
    21961 acgtccggcc attttatctc cgaccttaat cttacgtttt tgagcgatgt aaacacgaac
    22021 caacatgtta acacctgatt gcaactcatc tccatttaca cgtgtaaaga tcttaacatc
    22081 acgaacgaca ccatcggcac cgtgtggtac acgaagagaa gtatcacgca cttcacgaga
    22141 cttgtctcca aagatagcgt gcaagagacg ttcttcagct gaaagatctt tctcaccctt
    22201 aggtgttact ttacctacaa gaatatcacc ttctttaacc tcagcaccaa tacggataat
    22261 ccccatttcg tcaaggtctt tgagggcatc ttcaccaacg tttggaattt cgcgagtgat
    22321 ttcttcaggc ccaagctttg tatcgcgcgt ttctgattcg tattcttcaa ggtgaacaga
    22381 tgtgtagaca tcgtccttca ccaagcgttc gctcatgata acggcatcct cgaagttgta
    22441 accttcccaa gtcatgtagg caacgattgg gttttgtcca agcgccattt ctccattttc
    22501 catagaaggt ccgtcagcga tgaaatcgcc tttttcaacg acatcaccaa cttttacgag
    22561 agtgcgttgg ttgtaagcag tacctgagtt tgaacgacgg aatttttgga tgtggtaaac
    22621 atccaatgaa ccatcttcac gacgaacttc taccttgtca gcatctgcgt aagtaacttt
    22681 accatcatac tgagcaatca cagccgcacc agaatcgtgg gctgcttggt attccatacc
    22741 agtaccaacg taaggtgcct gaggattaat caatggcaca gcctgacgtt gcatattggc
    22801 tcccatgagg gcacggttgg agtcatcgtt ttccaagaaa ggaatacatg ctgtcgcaac
    22861 ggcaactacc tgttttggtg aaacgtccat gtagtcaaca atattagctg gatactcttg
    22921 gttgacccct tggtgacgtc ccatgacaat cttctcagca aaggttccat cttcattcag
    22981 acgagagtta gcctgagcta cagtatattc atcttcttca tcagctgtca accaaacaat
    23041 ttcgttcgtg acaacacctg tttcacggtc aaccttacgg tatggtgttt gaacaaaacc
    23101 atatttgttc aagtgtccgt aagatgacaa gttattgatc aaaccgatgt taggtccttc
    23161 aggtgtctcg attggacaca tacgaccata gtgagtgtag tgcacgtcac gtacttcata
    23221 tccggcacgg tcacgagtca aaccaccagg tcctaaggct gacaaacggc gtttgtgaga
    23281 caactcagaa agcgggttgt gttggtccat gaactgtgac aactgtgatg aaccaaagaa
    23341 ttctttaact gcagctgtta caggacggat attgataatt tgttgtggtg tcaagacttc
    23401 attgtcctga acagacatac gttcacggac attacgttcc atacgagaaa gtcccaaacg
    23461 tacttggttg gcaagcaatt caccaaccgc acggatacga cgatttccaa ggtggtcgat
    23521 atcatctaca cggccaagtc cttcagccaa gttgaggaag tagctcatct cagcaaggat
    23581 atctgcagga gtcaccgtac gaaccttgtc atctgggtta gcattaccaa tgatcgttac
    23641 gacgcgatct ggatcagttg gagcaacaac cttgaatttt tgaagaacaa caggctcagt
    23701 cacaacggct gcatcgtttg ggatgtagac aatcttgttc aagtcgccat ccaaatggct
    23761 ttcaatgctt tcaatcacgc tacgagtcat aatcgtacca gcttctacca agatttctcc
    23821 agtttcaggg tctaccaatg gctctgcaat ggtttggttg agcaaacgtg ttttaacatt
    23881 gagtttttta ttgattttgt aacgaccaac tgctgccaag tcatagcgac gtgggtcaaa
    23941 gaagcgagcc acaagcaagc tacgtgagct ttcagccgtc ttaggctcac ctggacgaag
    24001 gcgttcgtaa atttctttca aggcttcgtc tgtacgagag tccattggat tcttgtggat
    24061 atctttttca acagtgttgc gaaccaattc gctgtcacca aaaatatcaa agatttcatc
    24121 atcacctgag aaaccaagag cacgaaccaa ggttgtaaat ggaatcttac gagtacggtc
    24181 gatacgagtg taggtgatat cttttgagtc gctttcaagt tccaaccaag ctccacggtt
    24241 agggataaca gttgaaccat agcccacctt accatttttg tctactttgt cgttaaagta
    24301 aacacctggt gagcggacca actgagaaac gataatacgt tcaccaccat tgatgatgaa
    24361 agtacccatt tctgtcatga ttgggaaatc accaaagaaa acttcttggg tcttgatttc
    24421 gcctgtttct ttattgatca agcggaaggt tacaaaaatt ggtgctgagt agctagcatc
    24481 gtgaatacga gcttcttcta gcgtgtattt tggttccttg atttcatatc caacaaattc
    24541 caactccatt gtgtctgtga agtttgaaat tggcaataca tcttcaaaca cttccttaag
    24601 accgtggtct aggaaagctt tgaatgagtc agtttgaatt tcaatcaaat ttggtaagtc
    24661 aagaacttct ttgattcttg aaaaactacg acgggtacga tgtttcccgt attgaacgtc
    24721 atgtcctgcc aagatgattc tcctttgtaa ataagttcca agccttgtca atcaggcttt
    24781 tctaatcgcc atatggttgt aaacccctta tcaccgtgtc ctcttgacga attttcagaa
    24841 tctttaagcc tctgttacaa atgctcaaaa tcttgaaaaa aagcacaaaa agagcagcta
    24901 aatctgactt tttcagaaga tttaactgct gtgagccttg tctggacaat atttcagaca
    24961 aaacctacga caaatgatta cccatattat accctattta gctagatttt tcaaggggat
    25021 tcagtaggtt tttggtaatt tttttcccat agaaaacttg gcatcacatt cgaatcacgc
    25081 tatggtacaa aaaactgaaa aaactattga ctgaaaatca ttttcaaggt ataataataa
    25141 acgttaaggc ggtatagcca agtggtaagg cacggctctg caaaagcttg atcgtcggtt
    25201 caaatccgtc taccgccttc tataacttga tttatcaggt ttcaaatgaa cagaaagccc
    25261 aatttgaagg gcttttttta ttttccctcg aataaatacg tataacttta aaaacttttg
    25321 gagcgagttt gtggcagagt tctttccatg gcataattcc cttttgaaat caattgaaaa
    25381 aagcttcgtc acgcctggtg acaaaagcct ctagtttatt ctgtttcttc ttctatttcg
    25441 acttctgtga tttggacttt taccttggta acacgtccat tcttcacttt atcattggtt
    25501 aagataaact gtttgttttg gctgaccaat tcatagctga gtttctcagt cgttggaatg
    25561 gttcccactc ctgtcaaata ataaccagcg atggtatcaa cgtcatcact ttccagttca
    25621 acatcaaagt aattattgaa atcattgagg gtcatagttc cttgaacaat gtaggtatcc
    25681 tcgccaatct gatgaacatc tattgctgct ttgtccgttt catcatcaat ttcaccaaca
    25741 atttcctcta agaggtcttc caaagtcacc aaaccagcca taccaccgta ttcatccagc
    25801 aagattgcca tttgtctttg ggtatttcgc agttctttta gcaagtcatc cacaaaaata
    25861 gtttcaggta caaaaagtgg atcttgtaaa attctcttcc aaacaatatt gtcaaaaccg
    25921 tccacaaagc ctgccttaag gagactcttg gtgtgaatga ttccaattac attgtcctta
    25981 tccccatcat aaaccgggat acgagaataa ttttgtttta aaatactttg gataatggct
    26041 tgactatcat cctgaatatc caccataaag gcatccgttc gaggcaccat aacctctcgt
    26101 gccatcagtt catcgagcga aaagacacct tgtagcatct caatctcatc agcatccaat
    26161 gtttcttcac tatttgtcag catataggca atttcatcac gggtcatctt ttcatccgca
    26221 tcatcgaatg acataggagt caaatggctc aagaaattgg tcgaagcagc taaaagccaa
    26281 acaaaaggac tgactagttt tccgatccca atgataatcg gcgctgtacg aattgccaag
    26341 gcatccttta gattaagagc gattctctta ggatataatt ccccaaaaac gatggaaata
    26401 taggtcaaaa atgccaagga tagaaaagtt gccacggctt gtgctgtttc gccattccca
    26461 agccaagagg caatcacacg tcctagagta tcagttaaac tcgcccctga taagattgta
    26521 atcagggtga ttcctacctg aatggttgat aaaaagtggt taggattttc tagtaccttc
    26581 agcaggcgga tgtagcgtct gtctccttct tccgcctttt gttcaactcg ggcacgatta
    26641 agagaaacca tggccatttc tgtggctgag aaaaaggcat ttaataccgt caagataaac
    26701 aataaaacaa attgtagcaa caaattctga ctacttgggt cttccatagt tcttctccta
    26761 aaatagtatc ttatccttta ttatatcaca aaatttaatc caatacatat tatttttttc
    26821 ttagcgtaac ttccatctct ctcccaaaac tggaagttag tctaagacgg atttccactg
    26881 atttcacgcg tttttctcat actaaaagct aggttgtggg aaactggaag ttagttttag
    26941 aagttactat tttttcttag tacctattct agccctgctt aaactagtaa aaagaactcc
    27001 tacatccata agtgacatag gagtttaggc ttatctttta ctgagttaca gttacttctc
    27061 cagttcggta atccagttga agtccctttt gaacattggg aactagaaca ttgaattcca
    27121 attctccatc cgaagacttg gcttcaatct gtgaagctga gggaactaaa tcctcgtttg
    27181 aagcgtagta aagggttaca cggtaacgga cacgcttgtt ttggtccaag gctttacgca
    27241 ccttgctttc atagtagttt tgaccagtcg aatactcggc ttgtgcctga tttgcccagg
    27301 ctgtctgaac agcaatgttt ttaggattgc ttgttgaggc atcaaaacca tccaaaccac
    27361 cgattaaggc atagcctaac aaatgacctc tatcgactgc atgggtataa gagcccttta
    27421 gattcttgac ctgatgccaa cctggaggag tccaagaagt tgaaccattc ccagtttctt
    27481 tacgattctt gtactgacga gtggccttag acaagagggc attagctacg gttggaacag
    27541 tttccttgcc cactgtcttt gttttattgt cagcgtaggg cttacttgaa accttggcat
    27601 ctagatttgt tttattacca ttgacgataa aagcacctga gccattccac tccagactcc
    27661 cctttatttg actcttgact gcgtctgtta agacactctc tgccaatgct tgactaggag
    27721 cttcagacgc ttgttttttc tgactaagat tggttttggg actattaggt gccgactgca
    27781 tctgcttgat ataatagctc cctgtagaca aaagcaataa cactagcagt ccgattagtg
    27841 tctgtcttgt ttttttgttc atatttctcc ttatctttag aaaaaggctg gttctccagc
    27901 ctaatttcct gtaaatttat gaatcaattc ctgccatttt gctggagaca ggatagccca
    27961 tggatcttga cccttgccca agattccata acctaccatt agaccgattc ctagagccag
    28021 agtacctaaa atcagtacta tgatgactaa aagtaaacga ttgattacgt agcttgattt
    28081 cttattcatc ttcatcgctt gcctcaatcc gctgaatctt agcacctagc tgcgccaact
    28141 tctcatggaa accgtagtaa cctctatcca agtgaaccaa tttaccgacc acagtttctc
    28201 cctgtgctac caaacctgtc aaaatcaagg ctgcactggc acgaaggtca gttgaaagaa
    28261 cttctgctcc ctgcaaaggc tgtccaccaa caatacgagc tgtatcacgg ataatctcag
    28321 aatgcaagcc catgcggcgc atctcttcta ggtgttggaa acgattttcg aaaactgtct
    28381 ccaccatggt tgattcgcct tttgcaactg tcatcaaggc tgtaaattga gcctgcatat
    28441 ctgttggaaa tcctgggtgg ggcaaggttt tcacatgaac agcttttaga ttttctagtt
    28501 gagaacgaac acgaattcct tcgtcttctt caattacttc aacacccatt tcaagtaact
    28561 tggcaatcaa gggacggttg tgctcccaga cagcgtctcg aatcaagaca tcaccaccag
    28621 tcatggcagc agctaccata aaggttcctg cttcgatacg gtcttggact acattgtgag
    28681 tcgtaccatg aagtttctca acaccagtaa tggttatagt ctctgtacca gcacctttga
    28741 ccttggctcc catttcatta aggagaatgg ctaagtcaac aatctcaggc tcacgcgcag
    28801 cattctcaat cactgtcacc ccatcagcca gagtcgctgc catcatcaag ttctgcgttg
    28861 caccaacact tggaaagtcc atatagatat gagcgccatg caagcgttct gccttggctt
    28921 cgatgtaacc agctgtctga ctaatcttaa cccccatagc ttccagacct ttcaaatgaa
    28981 gatcaatagg acggctacca atcgtacaac cacctggcat ggataccttg gcatgaccca
    29041 cacgggcaag gattggccct aatacaacga tggaggcgcg catcttgctg acatacttgt
    29101 aaggggcttc ctcagtgatg tcgccagtag catccacctt gacaagatga gcttcctcat
    29161 caaagtcaac cttggcattc aaaccaccaa ctacctgatt cataataaag acatccgaca
    29221 aaatcggaac attctgcaag acggtctttc cttcacttgc tagaatagtc gctgccaaca
    29281 agggtaagac tgcatttttt gctccctcga tcgtcacgct tcctaccaga cgattatcgc
    29341 caccttgaac cacaatttta tccatactcg tttcctttac tcttgatttt ataataatcc
    29401 tctaagcgct tcttgccaca aatgatacag gctaataaag aaagaactca ggatgtagcc
    29461 tatgacaatg ctaaaaaagg ctactaataa acgaactttt cttgtattat catctgtcac
    29521 ttttaaaacc ttctcccatc taacaagatc ctttaaaagg taaaaactca cataaataaa
    29581 gagcatatga ctacttagag tgaataataa ttgaaccatt tgactattat accatcttct
    29641 ctgtttgtgc gctagtttgg aaacttcact caaaaattag ggattgtttt tcaagtaatc
    29701 aatcgcatct tgtagggttt taacgggcac gattttcata tccgtcttga ttgttttagc
    29761 cgcttctagg gctgtttggt agttgttttt cgcgtccaga tgcgcctttt gttcttcttc
    29821 gctaacaggg ttatcaggag caaagaaaat agcagcacct gccctagccg aagctacaac
    29881 cttcttatca atacctccaa tgtctcccac attaccatcg cggtcaatgg tacctgtacc
    29941 ggcaacaata cgaccattac gaagatctgg gtgagctatt tgagtataga tagctagact
    30001 aaacatgaga ccagcacttg ggccgccaat accagctgtt gaaaagctaa ttgggacatt
    30061 gctgattacc tctgtacggt caatcaagcc gattccaatt ccatttttgc cattttccaa
    30121 ggtgataatc tttccttctg cagacttggt ttgcccatcc tcttcatagg tgaccttgac
    30181 ggaatcccct aatttttgag aactgacgta atcaatcaag tctttggaac tatcaaaggt
    30241 ctgatcattg actgctgtga ctgtatcaga gatattgaga atccctttaa aggttgaatt
    30301 atccgtcaca ttcaaaacat aaactccaaa gtacttgagt tcgatatcct taccagctgt
    30361 ttttagtcct tgatacttgg ccatattttg cgatgtttgc atgtagaatt gattgattcg
    30421 cataaattca acatcggaag aaccacctgt agtctcctga gcactacgaa tatctgtaaa
    30481 aggtgtcaac caagcataaa tcatatgagc taaagtggca tgttgaacac caaccgtaac
    30541 gaattgatag gcaccagctt ccttatcttc tgtgtcattt actttaagga cttggcgaat
    30601 atcttccgaa ccacctggaa cctctatata ataaggcaag ggcactacaa atgccaagaa
    30661 agtcacaatc aaggccgcaa tgacgtataa gggccatcta atcttttttt tcatttctta
    30721 tttcctccaa aatactctcg ggaacatggc aggcaatatc ctgaccaaac ttcaaaagct
    30781 ctcgaacacc tgatgaactg atatagagat gttcaggccg gctatgtaaa taaatagtct
    30841 ctatatcaga agacagctga tgattgtagt aatcaaaact agcttcatat tgcaaatccg
    30901 ccgcattcct caacccccgt actaggaaag tagcccccag tctttttgca acatcgacca
    30961 ccaattcatc atgagaagcc acgacttcaa cattttccaa atgtcccaaa gccttttcta
    31021 gcccccgttt acgattttca agagggagaa atccttgttt gtggggatta aaaaaaatac
    31081 ccacataaag cttatcaaaa agtctgctcg cccgttcaat gatatccaga tgcccatttg
    31141 tcatcggatc aaatgagcct gtgaataagc caatcttatc tgacatagac tgtcacctta
    31201 ctaattccat aaatcttttc cttccagata cccagacagg caatctcttc tggaagttca
    31261 acggccttat ccgtctcgca cacaaccata acatcttcag aaaaaagctc tctcttagcc
    31321 attttttcaa tatctgctac gatttgttcc ttggcatagg gagggtctaa gaaaacgagg
    31381 tcaaattccc cagatacctg ttccaatgcc ctctctgcat ccatcttgag gagttgaaat
    31441 tttccaactt ccttggtcat ctggatattt tcagccacga tggtctgagc cttacggtct
    31501 cgctccacca aaacagcact ggacatgcca cgcgatactg cttcgataga taaaccacca
    31561 ctacctgcat aaaggtccaa gactcgtccc ccttcaaagt agggaccaat catgttaaaa
    31621 atggctcccc taaccttatc cgaagtaggt cttgttgtct tgccttctag tgtcttgagg
    31681 ggacgtcccc catagattcc tgatacgatt ttcatactgt ttattatacc aaattataga
    31741 caaaaagaga aagaaaaccg aaccttgcgg ttcgattctc tacaaaatat tttcgtaagt
    31801 atcgcggact tcttgaggcc aaacacttgt ttgcacttct ccgatgtgtc tcttgcgaag
    31861 taggaacatg gccatacgag attgtccaat tcctccaccg attgtcaatg ggaataggcc
    31921 attcaacaaa gacttgtgcc attccaattc caagcggtct tcatcacctg taatttccac
    31981 ctgacgtcta agagtttctt catctacacg aattcccata gaagacaact caaaggctcc
    32041 acctaaagac tcattccaga caagaatatc accatttaga cccttgtagc cattctcaga
    32101 ctcgcttgtc cagtcatcat agtctggtgc acgtccatcg tgcggtttac catctggcaa
    32161 ctcgccaccg ataccaatca aaaagacggc tccaaattct ttacaaatcg cattttcacg
    32221 ttctttcggt gtcaagtctg ggtagcgttc taccaattct tctgtatgga taaaggtgat
    32281 ttgctttggc aagatagact cgatgtcata gcgagcttca acagctagct cagtcaggcg
    32341 aatagcctta taaatcttct caactgtttc ttttagataa acgatgttac gcttaccatt
    32401 tgggataacc ttctcccagt cccactggtc aacataaaca gagtgggttg catccaagga
    32461 atcctcatct ggacgaaggg ctttcatgtg gacaaagaga ccctctcctt caccaaagcc
    32521 aaaacgagcc aaggtgtggc gtttccattt agcaagtgag tgcaccactt cataagtagc
    32581 atcagggatt tggagaacct tgaccgatac tggattttcc acaccagaca ggttgtcctg
    32641 cattccgtca ccgaccttac tcaagatagg accttgaact tcgacaactt ctagcttatc
    32701 tttcaaatac tgggtaaaag tgtttttgac aaaggaaatt tcttcttgtt gatggataaa
    32761 acttttcttc atagacaact cctcaaaaat ttaataaacg tattatacac ctatttccaa
    32821 gaaaagaaaa gagaaaattt aaaaaaatca gtgtcactca aaacactgat ttcatagacc
    32881 ttttagtcat tgcgaccaaa gatacgtaga atacttagga aaagattgat aaaatcaaga
    32941 tagatgctga gagccattga caccacccag cctgtcgcta cacgaccttg tgattgttca
    33001 taggcgaggc gaatcttttg gttatcccaa gcaatcaacc ctgaaaaaac caaaaccatg
    33061 gctacgctaa tcatataatc aaagaagcca ctagccaaga aaatattgac taccatagca
    33121 atcagtaaac caatgagagc tgccatcatt gctcgaccaa tcccactcaa gtctttcttg
    33181 gtaaagatac caactgccgc catgacaaag aagagaaggg cgctcgatac aaaggcagat
    33241 aaaactgtac ccggagtata gaaagccacc acaaaactaa gggtaaagcc gtttaaaacg
    33301 gagtaaagta aaaatactgg aagagcagct ggactatttc ttgaagccat gctactggca
    33361 acgaaaacca aagccaactc cgcaaaagta gcaatggtca accagagacg cccctgcatc
    33421 aacaagtaaa ccaactgaga ctgaaagacc gtcaacataa ggcctgatac caaagcagat
    33481 agtccgattc ccagaccaac aaaggcataa accttagcgt aaaattgatt gagacctgca
    33541 cggtcatgta taatagtgtg attcatcctt ttctcctttt ctgtgaacat ctttccttga
    33601 ttataacaaa aaaagttaaa attagcttaa atggaagatt aaaataccgg ctgcaactgc
    33661 aacattcaaa ctctcggcct gccccttcat gctaatatgg accaactggt ctgcactttc
    33721 agccataagg ggactaattc cttgaccctc atttcccata actagtacaa aattttctat
    33781 agaaggcagt tctctgtaat caacagaatc tttagatagg gttgttgcta gcactgggat
    33841 agctaccttt ttagtttcgt caagaagcgc tggactagtc atccggtaaa tgggcagatg
    33901 gaaatgacta ccttgcatgg aacgtagggt tttgagactg tagatgtctg ccgacttatc
    33961 tgaaacaatc actcctgtaa aacctgctgc atccgcagtt cgaatgatag ttcctacatt
    34021 accgggatct tgcacatctt ccaaaaacaa gaacttgccc tgactcaaat cagcttgtcc
    34081 tacttcttct ttttgaacca ccgccacaat tccctgtgga gtctgagaat ccgccaaatc
    34141 tagcaaaata tcctctgaca cccagacagt ttgcgaaaaa gtagctaact gatctcgata
    34201 attttctagg gcaaagattt tctcaatcgt cactccagct tggacagctt cttcaaacaa
    34261 gtgccagcct tcaatcaaat aggcagactt gcggtatttt ttttggcgta atttcttggc
    34321 attttttacc acagaattgg cttttgaggt tataatagtc atagaaatat tataacacaa
    34381 tcaaaggggg ttggtatgca aaaggttaga atgattgccc aaggtagggt acagggagtc
    34441 ggctttcgtt ggggtgttta cagcttggca cttgaaattg gtggcatcac aggtcgagta
    34501 tggaataacg acgatggcac agtggaaatc ttagcccaag cagactcatc tgctatcatg
    34561 gcaaaattta tccaagaaat ccgaaaagga ccgacacctt tttcaaaagt aagctactta
    34621 gatgtcaaac taagcaactt tcctccctac tctgacttta aaatcgcaaa ttaggtctcc
    34681 agaactattg tatattttgt aaaaaaacag tagaatagaa aggtataatt tttaaagaag
    34741 gaataaaaac agtgaaatct attaaacgtt ttgcattctc ggctatggga gtggctatgt
    34801 tgcttgtctt gactggctgt gtcaatgtcg ataaaaccac aggtcagcca acaggattta
    34861 tttggaatac gatcggagcg cctatggctg aagccatcaa gtacttcgct actgataaag
    34921 gtctaggctt tggtgtcgct atcattatcg taaccattat cgtacgcttg attatcttac
    34981 cacttggtat ctaccaatca tggaaggcaa cgcttcactc tgaaaagatg aacgctctca
    35041 agcatgtcct tgagccacac caaacacgtc tcaaagaagc aactactcaa gaagaaaaac
    35101 tcgaagccca acaagccctc tttgccgctc aaaaagagca cggcatcagc atgtttggtg
    35161 gtgtaggatg tttccctatc ctccttcaaa tgcctttctt ctctgctatc tactttgctg
    35221 cccaacatac tgaaggggtt gctcaagcaa gctacctagg cattcctcta ggttctccaa
    35281 gtatgatttt ggttgcctgt gctggtgtcc tttactatct tcaatcgctc ctttcacttc
    35341 acggagtaga agatgaaatg caaagagaac aaatcaagaa aatgatttac atgagcccac
    35401 tcatgatcgt cgtcttctcc ctcttctcac cagctagtgt cacactttac tgggttgtcg
    35461 gtggtttcat gatgattctc caacagttta tcgtcaacta tatcgttcgt ccaaaacttc
    35521 gcaaaaaagt ccgtgaagaa ctagccaaga acccaccaaa agcaagtgct ttctctaaac
    35581 caagtggacg aaaagacgtt acccctgaac aaccaactgc tatcacaagc aagaaaaaac
    35641 acaaaaatcg caacgctgga aaacaacgtt cgagataaga agaaaaaggc ttagctgatt
    35701 tgctaagtct ttttgcaaat caaaagcccg atgtttccat caggcttctt ttctatccat
    35761 gtacacgttt catataatct tgataacttt cggtatccat gagtttttta gcgttcttga
    35821 cgcgatctgc tgttggtggt ttgactcctt cgagggaata tggaattcca agttcacgcc
    35881 acttgaactc acccatggtg tgataaggta gaatttcaaa cttatcaaca tttttgaggg
    35941 tcttgacgaa cttaccaagt tcaatcaagt catcatctct gtctgtcaat cctggaacta
    36001 gcacgtggcg aatccagaca ggttttccaa tatctgatag atactgggca caagccaaga
    36061 tatttttatt agtttggcta gtgacaatct tgtgctgttc ttcgttgatt tccttgatat
    36121 ccaaaagaac caagtcagtg acagccatga gtttgtcaaa cttctcaagg taacgtggtt
    36181 tattacggaa aggaagagca caggtatcca aggtacagtg gattccttgt tccttagcct
    36241 tggtgaagag agcaatcagg aaatcaatct gcaagagagc ttctcctcca ctgactgtaa
    36301 tcccaccctt atttccccag aaaccacggt agcgcaaggc ctctgtcaag acatcatcta
    36361 ccgtccgttc acgtgactta ttggactcca tagcccaagt gtctgggttg tggcaatact
    36421 ggcaacgcat gtgacagccc tgcaaaaaga caataaagcg aataccaggc ccatctactg
    36481 acccaaagct ttctgtcgaa tgcaccattc ctgtcacttg tccataatca attgtttctt
    36541 cagacatatc gttaccttcc ttgaaaacgt tttatagttt tattatatca cgacttgaag
    36601 gaaaaacaag atttttgcct attttttaga aagcaatctg tttttcaatt tcattttcaa
    36661 tctattatca gattattctt caaaatcgaa gccatataag gttgcaaaat agtcctcagg
    36721 gcgctctgca cggcggattt gacgggcttt accttcttcg gtatagagga tttccgcaga
    36781 acgtaatttg gcattatact ggtagcccat tgaaaatccg tgggcacctg tatcatgaat
    36841 taccagcaaa tcaccgattt ctgtatgagg cagttcgcga ttgactgcaa atttatcatt
    36901 gttttcacag agtgaaccaa ccacatctac cgcttcagct ggtccatctg gatgggtcac
    36961 gttgctaata tgatggtaag ctccgtacat agctggacgc atgaggttga ctgctgaggc
    37021 atccacacct agataggtac ggtaggtttc cttcttatga gtcactcttg tgactagagc
    37081 accgtgaggt gccagcataa aacgacccaa ttcggtgaaa atcttgacct gaccaagacc
    37141 tgctgacgta agaacttctt catacacctt acgaactccc tcaccaatca aggcgatatc
    37201 gttcggctcc tggtctggac gataattaac accaataccg ccagaaagat tgataaagtc
    37261 tagcgaaatg cccaactttt ccttgatttc aacagccagt tcaaagagct gacgagccaa
    37321 ctctggataa tagagatggg tcacggtatt ggacgctagg aaggagtgaa tcccaaaagt
    37381 cttggctcct ttttccttca agatagcaaa ggcttcaaag agctggtcct tggtcatgcc
    37441 aaacttagcc tccccaggat tgtccataat gtctgtcccc agttcaaaaa cgcctccagg
    37501 attataacga caagagatga tttctggaat gcctgctact ctctccagat gttcaatatc
    37561 ttcaaaggca tccaagttaa tggtcgcacc caattcacgt gcataggcgt attccttgtc
    37621 tggcgtgttg ttggaagaga acataatctc agaacccaga aagtccagtt tatggctcat
    37681 caaaagctct acataactag agcagtccac accacaacct tcttcttgaa gaattttcaa
    37741 aatagctgga gttggagtag ccttaactgc aaaatattcc ttaaagccct tgttccacga
    37801 aaaagcttgg ttgacggctc ttgccttctc acgaatcccc ttctcatcat acaagtgaaa
    37861 gggagtcggg aactcggcaa caatcgcttc taactcttct ctattgataa atggtgtttt
    37921 cataagcttc cttctattct gtttgcaaag aaaggctggg acaatcgttc caacctttag
    37981 ttctatctct tatttatctt cgtcaaagat attgccaacc tcaacatcga tggcttggtt
    38041 cttgacatca atattggtta ccttcaagag tgacttgtag tcaaactgct tttcacgttc
    38101 ttcttgggca ttgtccgcaa agaccgctac acctgccagt tctgagtcga actcgcgcaa
    38161 gagactaatc ataccattga ccgttccgcc acctttcaag aagtcatcca caatcaagac
    38221 acggctgcct gccttaagac tacgttttga aaggaacatt ttctcgatac ggtcaccact
    38281 tgaacctgaa acatagttga cgctaacagt tgaaccttcg gtaattttca ggtcacggcg
    38341 cacaatgaca aaagagacat tgaggacatt ggcaactgca tttgcaagtg gcacaccctt
    38401 agttgctacg gtcataaccg cgtcaatttt ttggtccata aagcttttgg caataatacg
    38461 accaatattt ttcaagatgg ctggtgtgct aagcaaatca gacagataga tataaccacc
    38521 tggcaagata cggtcacttt ctgacaactt ggtacgcaag tcttcaacca tttccttagc
    38581 atcctgactc gaaatagacg gtgtgaagat gacacctccg ccagccccag tcactgtctg
    38641 gatatgaccg atttcaattt cctcaaaggc gcgtttgata atgacgatat cttctgagat
    38701 ggatgattta gcagactcat acttttcagc aaaagtattg agactagtta gtttataagg
    38761 attattaatc aaatagttgg aaatgacaac catccgatca cttcttctta atttcatttc
    38821 tatttcctat tccattttta ttcaaaaaat caaaaagcaa actagaaagc tggtcgctgg
    38881 tggttcaaaa cactgttttg agattgtcaa tagaactgac aaaccctgta atatacctgc
    38941 atatatacat acgacaaggc gatactaccc tagtttgaag agattttcga agagtattca
    39001 tttttgtctt ttacttatta taccatattc acataaaaaa acgaacattc ttatcctaaa
    39061 aaatgctcat ttttcttaaa ttatcaatct aaatctggtt tatagaagga acgattatcc
    39121 atagcgaaga ttttattggt catctctcct ttatccacca aagccagagc tgttgacatc
    39181 atcatcatgc ttgcatccag attgtcaatc atatggataa tctctgcctc cataatacgt
    39241 ggacggactg gacttccata ttcaagcaag ccgtggtgac tgaggatgac atgacgaagc
    39301 aaaacgactt cttccttggt atcatcgatg ccgagttcca taactgtctt ggtaatttcg
    39361 ctatcaatga gagcgatatg tccaagaaga ttacctcgca ctgtgtactc tgtctggtct
    39421 ggccccgtca actcgataac cttagctaag tcatgcagca taatccccgc atagagcagg
    39481 ctcttattga gctgaggata aacttcgcta atagcgtctg ccaaacgtac catggtcgcc
    39541 gtatgataag ccaaccccgt ttcaaaggca tggtggttgg tcttggcagc tggataggag
    39601 tagaattcct tatcatactt ggtgtagaga tttcggacaa tccgttgcca gacaggattt
    39661 tcaattttga aaatcatttg cgacatgtag tcacgaattt ccttgacatc aactggtgac
    39721 ttgaccttga aatcggctgg gtcattgggt tcaccagctt gaggcaggcg gagagtaatt
    39781 tgattgactt gaggggtatt gttataaact tctcggcgtc ctttcatgtg gacaacctta
    39841 cctgcggtaa aggcctcaat gttatgaggt tgggcatccc agagcttccc atcaatctcg
    39901 ccactatcat cttggaaggt aaaggctagg tagtttttcc cagctcgagt ttgcctcagg
    39961 tcagctgatt tgattaggta aaagccttca aatagctcat cttttttcat gtgactaatc
    40021 ttcatattct tcctcatttt cttgaaaatg gagtagatca agcgcaggct caccttctga
    40081 caactcaatg tgacggagcg tccgctcgat agctatggta cgacggttta ataattcatc
    40141 aatattgcca gaggcatgtt ggagatgttt ttgtgccttg accagaatac caccaaactt
    40201 gccaaactcg gtcttgacac tggcaagagt cttgctgata tggtcggcac tcttttggat
    40261 attaagggtc ttgaaaccaa ctgatagaga gttaagaagg gctgataggg tacttggtcc
    40321 tgcaacaata atctgttctt cccgtctcaa atcatcaaag aagaccggat tgcgcacaat
    40381 ctctgaataa agaccttctg tcggaacaaa caagattcca aagttggttg tccgaggtgg
    40441 tgctatgtac ttgttcctaa tatccctagc aaagcgcttg acgcttgcta ggagtgactt
    40501 acgacagcgt tcaatctcat ccttgtcacc tgtctcatag gcttcttcca agcggtaata
    40561 atctgccagt ggaaacttag agtcaattgg cagatagacg tattcttggt cgccttgtcc
    40621 gggtaacttg atggcatact ccactcgttc actagagttt tcaaccgttg cgtattctcg
    40681 ttcgtactgg gcaggtgtca tgatgtcttc aataatttgc cccagttgca attctcccag
    40741 aatccctcgc gtcttggttc cagagagaac cttgttaaga gctccgacat cacgggcaac
    40801 tgtctgcatt tctccaaggc cacgattgac agactccagt tgtttagaaa ctgtctcaaa
    40861 ggaagcctgt aagcgtgtct gcaaggtctt ttctagtttt tcctcgaccg tctggcgcat
    40921 ttgttccaaa cgttgctcat ttgattcctg caaggcttgg agacgttggt ctgtcttgtc
    40981 tctagtttgg aggagattat ctgtcatttc ttgacggact tgggtcagac cttggtgcaa
    41041 ttcaatccgc acttcttgca aacggtcgct gacaaccact tccaaatctt tttggtctaa
    41101 ctggctggct tgtctggctt ggtcaaagcg gtaatccaac tggtctgaca aatgatctgc
    41161 ctgatcctcc aagctcttac ttaagtgttt ctcctgccta tcctgccttt gccaaatcag
    41221 aaagagacca gctagattgg caattaataa tagaataagt aaactttcca tcctacctcc
    41281 tgtccttgct atgcagtacg accacataac catctgggca agttaccgac acttccctat
    41341 ctatatattc gttagaagcg tacacttttt taaagaaaaa attttcctct gtcaactcat
    41401 acttggctcc aagaatagtc agctggctat cccgaactgg cataaaggct agatagtcgt
    41461 agtctgaacg aggttctagc tgactgattc cttctggaca ataagtaatc aagttttgcc
    41521 catcctcaat ttctatttga tgcatatagg gtgccaactt aggattgcta ggcagaaaga
    41581 cattggccaa catatggtca atacggccac ccaaggcacc gaaaatagta acctgagcct
    41641 gaggattttg cttaaagatg gtcaagagag ccaattccaa atcagtatca tctttttctg
    41701 gccgggcttg gacaaaatac tgggcacgtt tttgaatcac ctgtcgctct tcttccgtca
    41761 cagaatcaaa atctccgact gctagagcaa gaggcaaatc ttcttccaag atccagagcg
    41821 agcctcgatc cacaccaaca aaaccatcaa agtccgtccg ataatgaccg cggtctccgc
    41881 ctgcaaaaac ggcaacccta gtccagttgt tttctgagag tttgtactcg ctcattgaca
    41941 tctcccttaa agacatagga acctgctaca aaaacggtcg caccagcttc tttggattga
    42001 gcaatagttt ggtcatcaat cccaccatcc acttcaatct caaagttcaa acctttttca
    42061 tcacgaaggg caaccagctc acgaacctta tccatggttt ctggcagaaa ggcttgacca
    42121 ccaaatccag ggttaactgt catgactagg acttggtcaa ctagatgaag cacatgctta
    42181 atcgcttcaa ctggtgtacc aggattgata acaactgatg gcttgacacc gagtgaacga
    42241 atcttttgga gggcaccatg aatatgaggc gttgcttcca catggatact aataatatcc
    42301 gcacctgcac gcacaaagtc ctctaaatga tgctcagggt ttgacaccat caagtggcag
    42361 tcgaaaacca tcttactatg aggacgaaga gcttcgacca cacccgcacc aaaactgatt
    42421 tgcggcacaa aatgaccatc cataatatcg atatgggcat actctgcccc agttgcttct
    42481 aggcgtttaa tttcacgttc aaagttggca taatctgctg ccagaattga cggagcaatc
    42541 ttgtattgag acataggttt ctccttattt tggaattttt ttgctgactt ttttataggt
    42601 ttctctgcga ttttcaattt cgctgaggaa ttgcaggtag ttgtcaaaac ggaagggtgc
    42661 aatggtacct tcttcaactg ctggcttgac agcacaggac ggctcatggg tatgggtaca
    42721 agtacggaat ttgcagtctc gactgacagt ggcaatctct ggaaaggcct gattgaggtc
    42781 ttcagccgtt gatacttcat aatccagtga tgaaaagcct ggtgtgtctg cgattttacc
    42841 cccattgagg ttgtaaaaac taacagctcg agtggtatga cgcccgcgac ccagactgtc
    42901 tgaaatttct cccgtttcaa gattaagatc tggtgcgatt ttattgagaa gagttgattt
    42961 cccaacaccc gtctgcccca taaagaccgt aaccttgcct gttaacaaag gcaggagttc
    43021 ctctttactg gtcacaaagt catatccgat gtcaccatag gtctgctggt aaaaatccag
    43081 ttctcccccg tcttccaaca aatccatttt agaaatatag acgatgggat gaataccctt
    43141 atgctccaaa agaaccaaga aacgatccag caaattgctg ttaaaatcag gttccttgac
    43201 agacatgatt actacagctt ggtcgatatt gacaataggc ggacggacca gactgttttt
    43261 ccgttcgtga atcttgagaa tatagccttc tgaattttcc tcggcagaga aatctaccca
    43321 gtccccaacg taaggggtat gccctttttt acggaaattc ccacgcgcgc gtgtttgata
    43381 gacttggcca tcactctcta catagtagaa cccagccaag gctttaatga tttgtccctg
    43441 caaaataact cctttaaaat tgttagttcc attataacaa aaaaaagcta ttttagctta
    43501 gcttctcttt acaatttcga taagtctatt ctaaaagaaa aagatacact cacgctttag
    43561 ataccaagtt ttatacaaaa ataacgaatc tacctcctta tataaaaaca ggcgaacaga
    43621 gagcctaaaa ctccctgttc gctttacttt ttctgtgtgt aatagaaaaa acctaataaa
    43681 gcaagacaaa aaatatgaat ataaactcca tacatcatgt ggggaaagac agactctata
    43741 aaatagcctg gtagatagat gattggaaat tgatagaaat cataggtcgt tagagatagt
    43801 aaacaaagaa catacataaa tactgctaca attagaaccc atccttgctt tcgccataga
    43861 aaaatcatca ataagaacag acaaagtaga tagattgacc aatttcgcaa cataaattga
    43921 aaaccataaa tcatactttc agtcgtttct ccatcaatca catcaactac tttatagaaa
    43981 ggtaaacaat agctcactaa aaaaagaagg ggactaatta tttttttcat attctctacc
    44041 atggattatt ttgcaagtaa gctgaccatc tatctccata tcgaatcaaa ttaacagtat
    44101 aattagttac tacccgattt tcacctggtc caaccttaga aaaacctgtg ctatactccc
    44161 aactacttct tgcacctgga tgaaaccatt tttgctggga tgaataccaa ccaccttgtc
    44221 taacttccac acttgaagat tctatttcga tatccctttc atggaagtca actcctccac
    44281 ttattttagt aatatttttt tgtacacctc catcataact cacccagtga acaacagtat
    44341 acaattccac actataagta ctatcaaact gactttgatg agtagtaatg ttttgagtat
    44401 aagcgtgcac tttctgtata ccaaaaatat ggtctaatat attcgttggt ttagcaagct
    44461 tattgtaacc ctcttcaaca aaagtagcct tctctaaatc agcggtataa acagtttttc
    44521 cttgtactac ttgattgttt atagaagtaa tacggctatc cacaacaatg ggggccacca
    44581 tatctccatc gctagtttct attttagctg cctctttcac ctcatataca actcgatttt
    44641 cttcagactg aatcacttct accccatttt tttcaggtat agataatcta gtttgcccat
    44701 tagaaaccgt tatatttgga ccaatattct tctcatttgc ataagtcgca ataggaaatc
    44761 ctgatagaac cactgcacac ataaggctat tgactaattt ttttctcatg aatatatcct
    44821 tcccattttc aagaggagta aaaatagcta atataagatg aacgtttcct tatatttcag
    44881 aataggatat ctatctgaaa gcaattcaca ctcctatagg taactgttcc aaatcttggc
    44941 tacatatatt tcaatagttt gctacaaaaa actcctttct aagtctattg aacatgccct
    45001 tattcaccta ctaatatatc acaaaaataa ataaatacaa gactgttttt tctactagtt
    45061 ttatgataga atagtattgt tagggtaaat ttcatatata aatgtcgagt gaaaaatcga
    45121 tggagcagaa atcggtagac aaagactcga tttcgttggt ccagccccac aaggctaatc
    45181 aggtatttca cgagtttaaa aatctaatga agtgcccaat caactactga ttcattgatt
    45241 taatacgaac tatagtggat tgaacctaga aatagtacac taaggattct aaaacgtttc
    45301 tagaaattaa tttgactttc ctaatctctt tgttcatatc ttatttcaat ctactatata
    45361 taccaaaatg ctgggacaaa agtctttaaa atcagagaaa cgcatattat caggtgttgg
    45421 aaaaccttga taatatgcgt tttatcatag aaagatctac ttcatttttt accaaaatta
    45481 agtttttgtc cctgcatctt agagtccttg ccctttaagt gcatctgcta ggctggcaaa
    45541 ctcttccaag ctgagagctt ccccacgcac acttggtgac aagcctgctt ggtccaaagc
    45601 cttggtcagc ttgtccttga cctcttcagt cttgccaaag taacctgtca agttattcca
    45661 caaggtcttg cggcgatggg taaaactagc cttggaaacc ttaaagaaaa agttctcgtc
    45721 ttccactgct acagctggca ctggacggcg caccattttc aagatggctg agtctacatt
    45781 tggtgctggc acaaagactg tacgcggcac gataaaggca accttggctg tcatgtaata
    45841 ctgcacagcg atagacaagc taccgtaagc cttggtattt ggttgagccg agatacggtc
    45901 cgccacttct ttttgcatca tgaccacaaa ctcactaaaa ggaatgccac tctcgattaa
    45961 gtgcatgaga ataggcgttg tgatgtagta aggcaaatta gccactacct tgattggcag
    46021 gtcaggattt ttgaaattct ggatatgttg cgccaaatcg accttgagaa tgtcctcgtt
    46081 gactacagtc acattgtcaa aatcacgcaa ggtatctgcc aaaatcggta ccaaacgatg
    46141 gtcgatctca aaggccataa cttctgctgc acgctcagcc aaaaactcgg tcaaggcacc
    46201 aatacctggc ccgatttcaa tgacattgac ctggtcatca atctcagccg tatccacgat
    46261 tttttgtagg atattggtat ccgtcaagaa attttgccca aaggactttt taaaggtaaa
    46321 accgtgacgc tccagcactg ccttggtcac gctataatct gcaattctca tctattctct
    46381 tttctattat ctgttactac tattgtaaca cattcccctt gtattttggg ggtgaaaatc
    46441 ataccaaaaa actatctttc ctcatgaaga aagatagtct tggaaatctt taaaagtggc
    46501 cttagcgctt ctctcgaaac atacgtt
//
LOCUS       DAVBNZ010000009        44398 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000009 DAVBNZ010000000
VERSION     DAVBNZ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44398
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.009"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..228
                     /locus_tag="VQ860_000518"
     CDS             <1..228
                     /locus_tag="VQ860_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3119006.1"
                     /translation="TTPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIE
                     KTWAHIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            complement(263..1060)
                     /locus_tag="VQ860_000519"
                     /pseudo
     CDS             complement(263..1060)
                     /locus_tag="VQ860_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1325..1561
                     /locus_tag="VQ860_000520"
     CDS             1325..1561
                     /locus_tag="VQ860_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET3119007.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1792..3078
                     /locus_tag="VQ860_000521"
     CDS             1792..3078
                     /locus_tag="VQ860_000521"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET3119008.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(3310..4458)
                     /locus_tag="VQ860_000522"
     CDS             complement(3310..4458)
                     /locus_tag="VQ860_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3119009.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(4633..5445)
                     /locus_tag="VQ860_000523"
     CDS             complement(4633..5445)
                     /locus_tag="VQ860_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HET3119010.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            complement(5483..5863)
                     /locus_tag="VQ860_000524"
                     /pseudo
     CDS             complement(5483..5863)
                     /locus_tag="VQ860_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            complement(5876..6139)
                     /locus_tag="VQ860_000525"
     CDS             complement(5876..6139)
                     /locus_tag="VQ860_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3119011.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(6139..6372)
                     /locus_tag="VQ860_000526"
     CDS             complement(6139..6372)
                     /locus_tag="VQ860_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119012.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            complement(6372..6740)
                     /locus_tag="VQ860_000527"
     CDS             complement(6372..6740)
                     /locus_tag="VQ860_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3119013.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            7025..7171
                     /locus_tag="VQ860_000528"
     CDS             7025..7171
                     /locus_tag="VQ860_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119014.1"
                     /translation="MNEEDLKELLELLATDYGRGYLDGVVGGLSMLLKISKEAEKYRK
                     EKYE"
     gene            7215..7589
                     /locus_tag="VQ860_000529"
     CDS             7215..7589
                     /locus_tag="VQ860_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119015.1"
                     /translation="MIETLEIKINKKTYFISARADVPVRYKVMFGRNLFDDFSKIKNN
                     KDETLSLCLLFCMTDKSSEEFCKFFIENNSYITSRHHYEAIRLFEKHFIFKPVTYSLE
                     DIVQILTIYLENTKTQIGGKNE"
     gene            7582..7785
                     /locus_tag="VQ860_000530"
     CDS             7582..7785
                     /locus_tag="VQ860_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3119016.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQVELAKQVSVASSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            7802..7999
                     /locus_tag="VQ860_000531"
     CDS             7802..7999
                     /locus_tag="VQ860_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119017.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            8010..8171
                     /locus_tag="VQ860_000532"
     CDS             8010..8171
                     /locus_tag="VQ860_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119018.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDREKRINGFKKIQDDEL
                     ERVRNKFNL"
     gene            complement(8166..8591)
                     /locus_tag="VQ860_000533"
     CDS             complement(8166..8591)
                     /locus_tag="VQ860_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119019.1"
                     /translation="MEYQALIQPVISIILAIISGLWSYVASKANNKAEIEKQAKEHSH
                     TVEKLEREFHHQIDTLKQQHAFELEKIKQAHELRLQELEKVSQLDTETDKSMKMNDLT
                     YKVFTGEVDFDKALKIANKASNSKQNLNKRFIQKTSKKS"
     gene            8645..9358
                     /locus_tag="VQ860_000534"
     CDS             8645..9358
                     /locus_tag="VQ860_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HET3119020.1"
                     /translation="MNEIFNFHGQEVRTLIIDDEPWFVGKDVADILGYSKARNAIALH
                     VDEDDALKQGLTDNLGRVQETIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRK
                     QGGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAKSLLKKRKA
                     RVVVCLGGIDSPAYADKTFAQSVFRQAEIDFKDHFNINRYDLLPKKFADAALAYWMTW
                     EPSTNTKMKIMKLNSFDEG"
     gene            9371..9628
                     /locus_tag="VQ860_000535"
     CDS             9371..9628
                     /locus_tag="VQ860_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3119021.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCD
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            9714..10034
                     /locus_tag="VQ860_000536"
     CDS             9714..10034
                     /locus_tag="VQ860_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119022.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIQVRNHAYERGREDKWQEIRKNIRREFKGFTYDNEPPVGLRPEPLALPEPKQSA
                     IRFL"
     gene            10050..10346
                     /locus_tag="VQ860_000537"
     CDS             10050..10346
                     /locus_tag="VQ860_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119023.1"
                     /translation="MQELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLRVKE
                     YLTDYEKLAKDYRYMTLKNKLLKIEKMELEGRYIYEDMRMKYRANRRKWGARYV"
     gene            10339..11166
                     /locus_tag="VQ860_000538"
     CDS             10339..11166
                     /locus_tag="VQ860_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HET3119024.1"
                     /translation="MSEIKWIKIKTDIFDDEKMCLIDASPDRDAIIVIWIKLITLAGK
                     LNTKGVLTISKNIVYTDEMLAQTFHRPLNTVRMALEVFEKFGMVEKIDGVIMLPNWEK
                     HQNIDGMEKIKEQNRNRAARHRQKQKLLAQNNESNVTDNVMDNVTVTHGNALDKELDK
                     DIEINNNKVMISSSLSENLKNSGIHLTDKSHQQLLDYVGLDGMSFDMLNRAVEKTSGS
                     HKPSFNYLIAILESWKKKGFTSIEQVDEDDRKYKEGKKSRQQNDKTSEQEVRDEWGF"
     gene            11306..12076
                     /locus_tag="VQ860_000539"
     CDS             11306..12076
                     /locus_tag="VQ860_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3119025.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEILKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            12091..12285
                     /locus_tag="VQ860_000540"
     CDS             12091..12285
                     /locus_tag="VQ860_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119026.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     LQVSKALRGSFGNFYPVEVE"
     gene            12285..12512
                     /locus_tag="VQ860_000541"
     CDS             12285..12512
                     /locus_tag="VQ860_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119027.1"
                     /translation="MLELYFVYNGHCKFFLGRFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            12639..12806
                     /locus_tag="VQ860_000542"
     CDS             12639..12806
                     /locus_tag="VQ860_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119028.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            12793..13002
                     /locus_tag="VQ860_000543"
     CDS             12793..13002
                     /locus_tag="VQ860_000543"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119029.1"
                     /translation="MKYDKQAEIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LRKKNKELRRKAEELEYDGRVKAKS"
     gene            12974..13303
                     /locus_tag="VQ860_000544"
     CDS             12974..13303
                     /locus_tag="VQ860_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119030.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMSQLVIAVYLIY
                     RGSEDET"
     gene            13293..13718
                     /locus_tag="VQ860_000545"
     CDS             13293..13718
                     /locus_tag="VQ860_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET3119031.1"
                     /translation="MKLNELIKKYKKLEGVWNAEGAELVRQIFLQDLEQLDKPQPVKV
                     PQCVAEYIEFKKKNNFHVYGLAWLNGYEVEKEKRYFVKIKGNIKENMLVYGELLKRYF
                     FTKSFSLDDVIYSHTRKELEAANFGWVFDCPGIEIEEVE"
     gene            13718..14232
                     /locus_tag="VQ860_000546"
                     /pseudo
     CDS             13718..14232
                     /locus_tag="VQ860_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502465.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            14229..14618
                     /locus_tag="VQ860_000547"
     CDS             14229..14618
                     /locus_tag="VQ860_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119032.1"
                     /translation="MIPKFRVWHHELGRLMSVKCMFFQDSEIEEFELNDALMNDYITA
                     YPDEIELMQSTGLKDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGMPAVYLKG
                     LGDGYAWTEYEEIIGNIYENPELLEDK"
     gene            14618..14854
                     /locus_tag="VQ860_000548"
     CDS             14618..14854
                     /locus_tag="VQ860_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HET3119033.1"
                     /translation="MNPEIIDNINKPSHYQGANGLEAIDVVHNFVGSLSGASAFFWGN
                     AIKYMLRFQKKNGLEDLKKARKNLDWLIEEMEHE"
     gene            14851..15009
                     /locus_tag="VQ860_000549"
     CDS             14851..15009
                     /locus_tag="VQ860_000549"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119034.1"
                     /translation="MNTHCMKATPLLPWGRLRKSAKKQELLNGASISEFAIEDICTFF
                     GIEIQERK"
     gene            15221..15622
                     /locus_tag="VQ860_000550"
     CDS             15221..15622
                     /locus_tag="VQ860_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3119035.1"
                     /translation="MKKLSDEELKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     TVGISKPTETIAIRIADDPTLKFLEGFKGIINKLLSNLVEEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAIMKGEL"
     gene            15811..16353
                     /locus_tag="VQ860_000551"
     CDS             15811..16353
                     /locus_tag="VQ860_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3119036.1"
                     /translation="MEFVSPIKDNDNIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            16517..16708
                     /locus_tag="VQ860_000552"
     CDS             16517..16708
                     /locus_tag="VQ860_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119037.1"
                     /translation="MVKEYRDDFLGEKAFEKLNKDIDANPEVGFEIVGYTQTAFVNGM
                     HIPLTAILVKWNNFFKESE"
     gene            16828..17148
                     /locus_tag="VQ860_000553"
     CDS             16828..17148
                     /locus_tag="VQ860_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET3119038.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            17286..17678
                     /locus_tag="VQ860_000554"
     CDS             17286..17678
                     /locus_tag="VQ860_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HET3119039.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYADMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            17671..19401
                     /locus_tag="VQ860_000555"
     CDS             17671..19401
                     /locus_tag="VQ860_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HET3119040.1"
                     /translation="MGNLDKAKKYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            19409..19627
                     /locus_tag="VQ860_000556"
     CDS             19409..19627
                     /locus_tag="VQ860_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119041.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            19645..20847
                     /locus_tag="VQ860_000557"
     CDS             19645..20847
                     /locus_tag="VQ860_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET3119042.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDIPYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            20831..21406
                     /locus_tag="VQ860_000558"
     CDS             20831..21406
                     /locus_tag="VQ860_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HET3119043.1"
                     /translation="MQKRNSYRATQFQTREEESGDLILSGYFIKFDEETELWPGYCEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFNL"
     gene            21403..22575
                     /locus_tag="VQ860_000559"
     CDS             21403..22575
                     /locus_tag="VQ860_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HET3119044.1"
                     /translation="MNKLLILGARMRNKADKVVELEESIKELNKRSELEAKKLEQAGT
                     DEEVSAVEKNLEDIQKESDEKEAEKEQLEKEIEDLKNQVEELNRKAPTYPSQEKRGGQ
                     KLERRDAIAKYIRTGQTRDIVGLKTTDSGSAALIPTEVLKPHFVNKTRNPLLDLVERV
                     KVNSGSGKYPVIKKTDGVMVSIDELKSNPELGKPAISEIDYSIKTYRGYVPVSQEMID
                     DADYDIMSIVEDEVFNQGDNTELSLVTAVLKTATQADAAGFDGIKDIYNKKLKSIYKA
                     SIVVTKSMFAALDKVKDKDGRYMLQTDVASPTGYSFGGKTIYKVDDTVFGNEGDMKFF
                     IGDVTEFVKEFDRSQVSVKWVNNDIYGQLLGLFIRLDIKKADEEAGFFGTYTDVVA"
     gene            22587..22877
                     /locus_tag="VQ860_000560"
     CDS             22587..22877
                     /locus_tag="VQ860_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119045.1"
                     /translation="MSYKVIRPFKDLADPENHDYAVGDIFPREGYEPTDSFTNGLLTG
                     ANTAGSIFLEVLGDDEPKKPAPETKEVKEEPAVEQEETVEETAEESAEEVEE"
     gene            22880..23161
                     /locus_tag="VQ860_000561"
     CDS             22880..23161
                     /locus_tag="VQ860_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HET3119046.1"
                     /translation="MDQGQLLELLKLKLGISTDLRDKPLKKIISSVITELTDNLGIEL
                     VGERADHEMFIVDYAAYRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            23148..23447
                     /locus_tag="VQ860_000562"
     CDS             23148..23447
                     /locus_tag="VQ860_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HET3119047.1"
                     /translation="MWNHEITLISKKVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            23444..23791
                     /locus_tag="VQ860_000563"
     CDS             23444..23791
                     /locus_tag="VQ860_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET3119048.1"
                     /translation="MSNDLADLIAKELAAYSDEVTEEVDKIAEQVTDETVDELKETSP
                     KRYGKYRRSWKKKKLANGSFVVFNAVASLTHILENGHLSRNGGRVAGIVHIKPAEEKA
                     IQNFEKRIKEIGK"
     gene            23788..24111
                     /locus_tag="VQ860_000564"
     CDS             23788..24111
                     /locus_tag="VQ860_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119049.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPDLPYLVYYESSPVINS
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            24123..24701
                     /locus_tag="VQ860_000565"
     CDS             24123..24701
                     /locus_tag="VQ860_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3119050.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIELIL
                     DTKGETTPIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            24713..25132
                     /locus_tag="VQ860_000566"
     CDS             24713..25132
                     /locus_tag="VQ860_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119051.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSANPHIKPYEQFFMEME
                     IFPIQEVGPVLMEMLNASMTTKKHQMSQNQLAKKSSQ"
     gene            25410..28169
                     /locus_tag="VQ860_000567"
     CDS             25410..28169
                     /locus_tag="VQ860_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HET3119052.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANKM
                     ESELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAQALDLTSRATRAAADGAAFYDKSIESVSESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFNSLPDPVKDFVVILGTV
                     VTAVGVIAPIFLTLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILAVINTVVSEISDFIMSIFGTVVTWWTENQELIRTSAETVWN
                     AIYTVISTILDILGPLLQAGWDNIQLIITTTWEIIKIVVETAINVVLGVIQAVMQIIT
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRRRQL
                     RGGFA"
     gene            28166..28888
                     /locus_tag="VQ860_000568"
     CDS             28166..28888
                     /locus_tag="VQ860_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3119053.1"
                     /translation="MIKHNELVIDGVRTSSFPFKIIVHDSPSIALGESKTALLEHGGV
                     SGAIVQTNKHRELVKKTYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVSDLEEVQPGLYMTKATFTCHPTKYFKDSDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSASETSFTIAGQVIRLERLTESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            28889..32110
                     /locus_tag="VQ860_000569"
     CDS             28889..32110
                     /locus_tag="VQ860_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3119054.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKETMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALARMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIAGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKDYQRTKNSQNVVTRIHARSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYISLTFDDKAGIGG
                     SRSSGGLSSAADAILGVTESAQEIALEKALQNADLDFDHKAGLLRQEISDDIELAKAR
                     AEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQAEALSRTKNELAGA
                     STLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKQTIANDIRPKQAQAEAE
                     IAKQVEALSRTKNELAGVKSAQATYKETTTRRLSELTNLANGKASKSELTQTAEELAS
                     RIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDV
                     TFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNNVF
                     IRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQRADSLDA
                     GVRSLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQ
                     EILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQDIPKTGIWTTSTYT
                     ATIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFY
                     AKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQ
                     EGTIWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRAN"
     gene            34106..35488
                     /locus_tag="VQ860_000570"
                     /pseudo
     CDS             34106..35488
                     /locus_tag="VQ860_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            35469..35672
                     /locus_tag="VQ860_000571"
     CDS             35469..35672
                     /locus_tag="VQ860_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119055.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMIASNFLSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            35675..36027
                     /locus_tag="VQ860_000572"
                     /pseudo
     CDS             35675..36027
                     /locus_tag="VQ860_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36037..36453
                     /locus_tag="VQ860_000573"
     CDS             36037..36453
                     /locus_tag="VQ860_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HET3119056.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            36457..36792
                     /locus_tag="VQ860_000574"
     CDS             36457..36792
                     /locus_tag="VQ860_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET3119057.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRVVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            36792..37748
                     /locus_tag="VQ860_000575"
     CDS             36792..37748
                     /locus_tag="VQ860_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3119058.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(38018..38197)
                     /locus_tag="VQ860_000576"
     CDS             complement(38018..38197)
                     /locus_tag="VQ860_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119059.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(38339..38488)
                     /locus_tag="VQ860_000577"
     CDS             complement(38339..38488)
                     /locus_tag="VQ860_000577"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119060.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            38770..39237
                     /locus_tag="VQ860_000578"
     CDS             38770..39237
                     /locus_tag="VQ860_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET3119061.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            39270..39367
                     /gene="ffs"
                     /locus_tag="VQ860_000579"
     ncRNA           39270..39367
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ860_000579"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            39424..39867
                     /locus_tag="VQ860_000580"
     CDS             39424..39867
                     /locus_tag="VQ860_000580"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET3119062.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            39869..40384
                     /locus_tag="VQ860_000581"
     CDS             39869..40384
                     /locus_tag="VQ860_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3119063.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            40398..41759
                     /gene="radA"
                     /locus_tag="VQ860_000582"
     CDS             40398..41759
                     /gene="radA"
                     /locus_tag="VQ860_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET3119064.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFFIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            41832..42329
                     /locus_tag="VQ860_000583"
     CDS             41832..42329
                     /locus_tag="VQ860_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET3119065.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            42354..42548
                     /locus_tag="VQ860_000584"
     CDS             42354..42548
                     /locus_tag="VQ860_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119066.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGISIFLALFYM
                     IPALYFLFRIGKNGNCQRRF"
     gene            42530..43153
                     /locus_tag="VQ860_000585"
     CDS             42530..43153
                     /locus_tag="VQ860_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET3119067.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            43298..44266
                     /locus_tag="VQ860_000586"
     CDS             43298..44266
                     /locus_tag="VQ860_000586"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3119068.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
BASE COUNT        13842 a         7628 c        10165 g        12763 t
ORIGIN      
        1 accacaccat cggttattat tatggataat gcaagattcc atagaatggg gaagttagaa
       61 cttttatgcg aagagtttgg gcataaactt ttacctcttc ctccctactc acctgagtac
      121 aatcctattg agaaaacatg ggctcatatc aaaaagcacc tcaaaaaggt attaccaagt
      181 tgcaatacct tttacgaggc ttttttatcc tgctcttgtt tcaattgact atattagagg
      241 cgagacattt ttcggttctt tgtcaactgt agtgggttga agaaagcgaa gatctagaaa
      301 ggacaaattt cgtcctttct tttttgaagt tttcaaagtt cctaaaacca aaggcattgt
      361 gcttgataag tttgatgaga ttattggtgg cttccagttt ggcgttggaa taaggtaatt
      421 gaagggcgtt gacgattttc tctttatctt tgaggaaggt tttaaacaga gtctgaaaaa
      481 gaggtggaaa agcaagagct gatagagatt atagtggtgt ttcaagtctt cggaatagct
      541 caaaagttta tctagaattt ctttattagt caagtgcata cgaaaagtag ggcgataaaa
      601 tcgtttatca ctcagtttct gactatcttg ttgaatgagc tttcagtatc gcttgatagc
      661 cttgtattca tgggatttcg gatgatggct tgtgttctgc tctcaagaac agttatgata
      721 ttgagcttat caaagtcttg agcaataaag ctcatttcca tctcccgatt gaaacagtca
      781 ctccccggac tgtttcaacg tcctaggaca taatctcagg aagacgcgaa aaatcatgct
      841 caaagtgaaa atcattgttc ttgcgaatga cagttgaagt tgaaatagac aactgatgat
      901 caatgtcggt catagaagtc tttttaatta gcttctgagc aatcttttgg ttgatgatac
      961 aaggaatttg atgattcttc ttgacgatag aagtttcagc gaccatcatt tttgaacagt
     1021 gatagcactt aaaacggcct tttctaagaa gaattctagt ttgaattttt tatactagaa
     1081 aatcagaacc ataataccta tataaaaata ttatagttct aataggattt acccaaaagt
     1141 tttaaggcgg tctttttaga actttaatcg tttgaaattt aggtagcaaa tttgtttcta
     1201 ttttgtcaac ttttcctatt tttatcttgt tgaggctggt attttaacaa ttcaggaatt
     1261 gatagtgaat gtgtaaaatt ttttgttaga ataagtttat aaaaaagaaa aggagtattt
     1321 gattatgtta caaaaaattt atgagcagat ggctaatttc tatgatagta ttgaagaaga
     1381 gtatggtcct acatttggtg ataattttga ctgggaacat gttcatttta aatttttaat
     1441 ttattattta gtgagatatg gcattggttg tcgtagggat tttatcgttt accattatcg
     1501 tgttgcttat cgtttgtatc ttgaaaaatt ggtaatgaat cggggtttta tttcttgttg
     1561 aggtaatttt agtaaatttc cgaactaatt tactctttta tggaaagata atagtaaata
     1621 gctagtaatt tttctaaatc attttttaat agttggaaat agcaaatctt tctattgttt
     1681 cttcttgata aaaaggcgat tttttattat aataaattgt aagatataat tgcaggtgag
     1741 agtcctgcca tgtatgtgag aaaggaagag cctgagggct cagacaaaat tatgacttca
     1801 gttgttgttg taggtaccca atggggtgat gaaggtaaag ggaagattac agacttcctt
     1861 tcagcgaatg cagaagtgat tgcacgttac caaggtggtg ataatgctgg tcacacgatt
     1921 gtgattgacg gtaagaaatt taagttgcac ttgattccat ctgggatttt cttccctgaa
     1981 aaaatatctg tcattgggaa tggtatggtt gtaaatccta aatctcttgt aaaagagttg
     2041 agctatcttc atgaggaagg tgtaacaact gataacttac gtatttctga tcgtgcgcat
     2101 gttattttgc cttatcatat cgagttggat cgcttgcaag aagaagctaa gggcgacaat
     2161 aagattggta cgacaattaa gggaattggt ccagcttata tggacaaggc tgctcgtgtt
     2221 ggaattcgta ttgcagatct tttagataaa gatattttcc gtgagcgttt agaacgtaac
     2281 cttgctgaaa agaatcgtct ttttgaaaaa ttgtatgaca gtaaagcgat tgttttcgat
     2341 gatatttttg aagaatatta cgaatatggt caacaaatca agaaatacgt gatagataca
     2401 tctgttatct tgaatgatgc gcttgataat ggcaaacgtg tgctttttga aggtgcacaa
     2461 ggtgttatgc tagatatcga ccaaggtact tatccatttg ttacgtcatc aaaccctgta
     2521 gctggtggtg tgacaattgg ttctggtgtc ggtccaagca agattgacaa ggttgtaggt
     2581 gtatgtaaag cttatacgag tcgtgtagga gatggtcctt tcccaactga gttgtttgat
     2641 gaagtgggag aacgtatccg tgaagtgggt catgaatatg gtacaacaac tggtcgtcca
     2701 cgtcgtgtag gttggtttga ctcagttgtg atgcgtcata gccgtcgtgt ttctggtatt
     2761 actaaccttt ctttgaactc tattgatgtt ttgagcggtt tggatactgt gaaaatctgt
     2821 gtggcctatg atcttgacgg tcaacgtatt gactactatc cagctagtct tgagcaattg
     2881 aaacgttgca agcctatcta tgaagagttg ccaggttggt cagaagatat taccggagtt
     2941 cgcaatttgg aagatcttcc tgagaatgcg cgtaactatg ttcgtcgtgt gagtgaattg
     3001 gttggcgttc gtatttctac tttctcagta ggtcctggtc gtgaacaaac aaatatttta
     3061 gaaagtgttt ggtcctaaga gatttttaag atttgtttaa gataggtcgg gtatactata
     3121 gacagttata agaagacctc ctaacttgtt gtaacaaata tcctaaactt ttctttttca
     3181 taataatctc ccttaactcc acccaatcag gtggagtttt ttagctctat ttcaggcttt
     3241 tggggactat tctaaaaata atttttcgat atttttcgga ttttggtcgg ggaattggcg
     3301 gggacttttt tagcgaatat gactaagaaa taggtctgtt gtcgcttcag caagttcgtc
     3361 ctctacttga ttgtaacgat ccgtcatata aacctttgta tgccccagcg cctggcttaa
     3421 ttgttcaagc ggaacccctg caataatgct ttgagtcgtg aagaagtggc gcatcatgtg
     3481 aggtgttaca tgcaatcctg ttgcttcatt cactagattg aagtttctat ttagctgatt
     3541 tggattgatg agaccacctt tctcgttgat agttatataa tccttgtgct gttccttgat
     3601 aattcctaac tttcgcttaa tcttagaagc ttcagctatc agataataga tcaggtctgt
     3661 tccgatatca tcaaggcaga catatcgctc tgaatccttc gttttaagcc ctcctttccc
     3721 ttttaaggtc tggttgcttc gactgtctct aagatgcagt atagcccgtc cgctgtcgtt
     3781 ctgagtgatg tccattggac gcaatccaaa gacttctcct cttctcaatc caaaaattgt
     3841 cagataggtc agagcgtaga attgttttgg cataatctct tctgcctttg ctatccaagt
     3901 cttgaactct ttgagagtca ctttcttgtt tgcagcaggg atatcactct ggccgatgaa
     3961 aacacctttc aagcgatttg agagcagatt tccatttttg acggcatcat tcagcaatgc
     4021 catgaagctg gaattgaggg tttgaacagt gtatctggta tggttctgca acttttcagc
     4081 gataaatagt tcatactcat ttctatccaa atttttaagc aggatagaac caaactttgc
     4141 cttgatatgg ttcttataga gattgtcatt gaggtagtag gaagtgtcat tccagcgccc
     4201 tgttgacaat ctcttttcag aatagatatc ccaatattga tcaagcgtta gattcgtatt
     4261 gatacctaat tcttgttctt ggatttgttg ctcaagctct accaaggctg cacgagcttg
     4321 agggagagtt gtgaaaccac ttttactttt ttctcttttt ttacctcgga agaaaaaaga
     4381 acgtctgaca tagtaacgct tgcctttagc agtctcatag taatagatat ttgggtattt
     4441 tgttttatta tatttcattg tattctcctt gtttatcggc ttctggacaa ggtctaaaca
     4501 ttgagaatat tgacatcacc cctttcatgg tgtaaaatag ggtatagaaa agaggccttt
     4561 ttaatggctg attttttata agggtaagct tcacaatcaa actttggcga gggcgattgt
     4621 ggggcttttt ttttattttc tgaatagttt gtatagttta tacaaactcc aagctgtcaa
     4681 agggactgca aggaatggag cgattggaat accaacaact ccaaaaaaga ctaagaaaag
     4741 atacagtgct gaaaatatga ttttattggc aggaagtttt ttcttaggag atgtttctga
     4801 aagattaatc tcgtttacta tatcagcgac actgtcacta acaatatttt gttcaatatg
     4861 ttcagtttca gttgttttag tttcaatagc ttcagtttcc gtaacttctt tattggaaat
     4921 gttatcatca attatctcag atgattcgct ctgaattact tctttttgtg aagaatcaac
     4981 aatggtaagg taaatttcaa aaccaacatc caaatcatta tttgtgacaa ctttttcttc
     5041 atactcgtcc cattctttat atgggccacc ttttatctct ccctctatta caaagttata
     5101 ttttttatta tcaaaatatt ttcgtattgt tttagcaatg gttgcaggaa catatcctac
     5161 atgattatca aatatcaaaa cttttatagc attaggatca tatctattat ctacttctgg
     5221 aacgagctca atattgaaaa agtctaaatc ttgatatttg aaaactttca gaccatattc
     5281 ttcaagttct tctctaagtt ccttagttga taaattgcta tagtactttg catattctgg
     5341 gattccgtta tcttcagcaa tcatattgca agcttctttt actgcttttt tatattttgt
     5401 cactccagcg actctgaata atattttttc aacagtcttt tgcatatatt tcccctctat
     5461 ataaatatct tcaatgcaat ttttaattta ctaatgccaa gtactcttcc ttgaccatga
     5521 cttcattagt catagttttt agattgtagt aagacatgaa tttgaggtaa tcaaactctg
     5581 tggggtcgtc taagctttct agtgcgtctt tcacgagatg atggatcata ttcctatcag
     5641 cttcgttttc acagcgtagg cgagcgtttt ggtactctga gcgtgtatgg tctttgtgtc
     5701 cgagttagtg tagggcgact tggatttgtt gttcaggagc taagttgtgg tcaatagcga
     5761 gtacgtttgt gtctggattg tagaaaccgc tactgtgcca gtttgaaccg tcgaagagac
     5821 aaagctctac ttgatattct tcgcagagtt tagcgagtat catagttctc cttcgttatt
     5881 tataaacatc tctgcggtgg gcgatttcca cggctaggac gactagttta tcgtcttgga
     5941 tatcacagat gatgcggtaa ttctctactc tgtatcgcca gtaacctgca aggttggctt
     6001 ttagtgcttt tccgtgttgt cgtggattgg tcgtgttttc aatgttttta gcaagccagg
     6061 ataggatttg ttttctggtt ggggtatcta gttttttaag ttgcttgaga gcttttttat
     6121 caatatctag ccgatacatt aagcaatatc ctctcgagat agtcctagtt catccaagac
     6181 ctcatccatg gtataagtag ctgggtcggc taaatactcc atataggctt ggtcggctgc
     6241 tcgtgcgtct tcgatatctt ccatgagtac catgaagtcg tcaaaatcca tggttgttgt
     6301 gtcgataccg tgtttggtta ggtagtccgt gatgtaggag tttttttctg tgaaattgat
     6361 cgtgatagtc attagcgttc tcctttgctt ttgaagtggg cggatagaac ggatgtgatg
     6421 aagtcgatat catcttcatt tagtggtttt ccgtcaaata acatggtgtt ggctgctgct
     6481 ttgcgtaagt ctatgatttg tccatttact tgagcaaatt catcacttcc agcgatagca
     6541 ggattatctg tccgtccgag taggtagtca gcacttacat taaaataatc agctatttct
     6601 tttaaaactt ttgaactagg attacttctt tttaatcgat ataaagtatt agttccataa
     6661 ccaagttttt cttctaaaat atttatagaa atcccctgtt tatcagctaa ttcttttatt
     6721 ttatcgaatg ctacaaacat taatttttca acctttctaa gcaaacgaaa aataatttta
     6781 aaatatttgt agaaaatagt tgacttattt agtcaaatgt tttaaaataa tattcgtaag
     6841 ctaaagagtt agcgaactag acaactaaaa aataaagcct tacaaaactg attggcgtcc
     6901 gtttactgta ggtaaaactt acttttagta ggtcttttct ctatgttttt attttaaaac
     6961 atttgactag agttgtcaag aagttcgcta actttttaga taatttttta aaaggaggtc
     7021 agggatgaac gaagaagacc tgaaagaatt attggaactc ttagcgacag attatgggcg
     7081 agggtatcta gatggagtag ttgggggact ttcaatgctt ttgaaaattt caaaagaagc
     7141 agagaaatat agaaaggaaa aatatgagta aagcaaaatt attagtcaca taaagtaggt
     7201 aaacgaggta ggaaatgata gaaacactgg aaataaaaat aaacaaaaag acatacttca
     7261 tatctgcaag ggcagatgtt ccagtcaggt ataaagttat gtttggcaga aatctcttcg
     7321 atgacttttc gaaaataaaa aacaataaag atgaaactct atcactttgt ctattatttt
     7381 gtatgacaga caaatcgtca gaagaattct gtaaattttt tattgaaaat aattcatata
     7441 taacaagtag acatcactat gaggcaataa gattatttga aaaacatttt atctttaagc
     7501 ccgtaacata ttcactagag gacatagttc aaatcctaac aatatatcta gaaaatacta
     7561 aaacacagat tggaggaaaa aatgagtaaa gaactaaaaa taattaaggc taaaattaaa
     7621 actcgtttga ttgagttgga tatgactcaa gtcgaattgg caaaacaagt atctgtagca
     7681 tcatcagtta tttcagagtt gctgaagtat ggaaaaggaa gtgattatgt gaaagaaaaa
     7741 gtcgtagata ttttgggtat tgaaaaccct tgggaaaata gttagagcat gaggaaatag
     7801 tatgaacaac gcagcgcaaa aagtaacacg gattgacaaa gatgcctggg agattgctac
     7861 ggagctggcg aacgagtacg gcgtatctat ttgtcacatc atcagcgaga gcgtccgcta
     7921 ctgtgcagag aatgccgaat ttaaggagat ggacgttgtc gttaaacgat tggtagtcgg
     7981 cagtaaggtg ctggagtagg agggtggaga tgaatgaact agtatggttt tactttgttg
     8041 tcataatcaa tcttatcatt ggttttgcta catactacgc tagcaaaaga gatagagaaa
     8101 agcgcatcaa cgggtttaaa aaaatacaag atgatgagct tgaaagagtt agaaataaat
     8161 ttaatttatg attttttaga agtcttttga ataaatcttt tatttaagtt ttgtttgcta
     8221 ttgcttgctt tattagctat ttttaaagct ttgtcaaaat caacctcgcc tgtaaaaact
     8281 ttgtaggtaa gatcattcat cttcatagac ttgtcggttt cagtatcaag ctgagatacc
     8341 ttctcaagtt cttgcaaccg taattcatga gcttgtttga ttttttcaag ttcaaaggca
     8401 tgttgctgtt ttagagtatc tatctgatga tgaaattctc tttcgagttt ttcaacagta
     8461 tgtgaatgtt ctttggcttg tttttcaatc tcagctttat tgttagcttt tgatgcgaca
     8521 tatgaccata accctgatat tattgcaaga ataatactaa tcacaggttg aataagagct
     8581 tgatattcca taagatttct ccaatcgttt tattttaatt ataccaaatt tagaaaggaa
     8641 ctttatgaac gaaattttta attttcacgg gcaggaagtc cgtactttga tcattgatga
     8701 cgaaccttgg ttcgttggga aagatgttgc agacatccta ggatatagca aggctagaaa
     8761 tgcgattgct cttcatgttg atgaagatga cgccctaaaa cagggcctca cagataattt
     8821 aggaagggtt caagaaacta tcatcatcaa cgaatctggc ctctactctc ttatcttatc
     8881 cagcaagttg cctcaggcta aagagtttaa gcgctgggtg acatcagagg ttttgccagc
     8941 tattcgcaag cagggcggtt tcattcgcga ggacttggac gaggatgcct ttatcgctct
     9001 gtttactggc cagaagaaat tacgtgagca acaggcgacc atgctggaag atattgacta
     9061 tctcaagagt gagcaaccga ttcacccaag ctatgctaaa tcgctcctga agaagcgtaa
     9121 ggctcgggtc gtggtttgct taggtggcat tgatagtccg gcttatgcgg ataagacttt
     9181 cgctcagtca gtctttagac aagctgagat tgactttaaa gaccacttca acattaatcg
     9241 ctatgacttg ctaccgaaaa aattcgcaga tgcagccttg gcctattgga tgacttggga
     9301 gccaagcacc aataccaaga tgaaaatcat gaaattgaac tcatttgacg aagggtagga
     9361 ggggaagaag atggacaatg ttctactttc actgtctgaa tggattaaat ccattatcaa
     9421 ggacacaatc acaaggctag tcgaaataga aaaagatagt gaccactatc cagagctgat
     9481 ggatgtgaac actacctgtg attttctagg aattaagtat gccacctttt cagataatta
     9541 tcgttactta aagggatttc caaaggaatt acctggtaag aaatggtcaa aaagagccat
     9601 caaagaatgg ctctctaatc aaatataata actttactaa aaggcttctg gacaaggtct
     9661 tagcaaaatt atttgactat attatagcac aaaaagagga taaggagata aaaatgtttg
     9721 aaccaccgat tttagaccag ctgatggggg ttggagcctt actgcttgga tttgcagggg
     9781 cttgccgtca tatcaaattg caggaacaac gcaaggaaga agaaagacga gaagagcaag
     9841 aatttgcgtc tatgattatc caagtgcgta atcatgcata tgaacgtggt agagaggaca
     9901 aatggcaaga aattcgcaag aatattcgca gagagttcaa aggattcaca tatgacaacg
     9961 aaccgcctgt aggcttgcgt cctgagccgt tagctttgcc agaacctaaa cagtctgcaa
    10021 tcagattttt gtaatgagga ggtcaggaaa tgcaagaatt gattgaatcg ctggataacc
    10081 tgattatgat tgttaaagaa ctggaaggaa gggaatcaac ttcaagacat tttattacga
    10141 tatgggaaaa cgattataaa aatctattac gagtcaaaga atacctaacc gactatgaaa
    10201 aactagcaaa ggactatcgt tatatgaccc ttaaaaataa gctgctaaag attgaaaaaa
    10261 tggagctgga aggcaggtac atctatgaag atatgcggat gaagtatcgt gccaatcgca
    10321 ggaagtgggg tgctcggtat gtctgaaatc aagtggataa aaatcaaaac ggatattttt
    10381 gacgatgaaa agatgtgtct aattgatgcc tcgcctgatc gtgatgcaat tattgtaatc
    10441 tggatcaaac ttataacact agcaggcaaa ttgaatacaa aaggcgtact aaccatttct
    10501 aaaaacattg tatacaccga tgaaatgctt gcacaaacgt tccaccgtcc gttgaataca
    10561 gttcgtatgg ctcttgaagt ttttgaaaag tttggaatgg ttgaaaaaat cgatggagtg
    10621 ataatgttac ccaattggga gaaacatcag aacattgacg gcatggaaaa aataaaagag
    10681 caaaatcgaa atagagcagc acgtcaccga caaaaacaga aattacttgc acagaacaac
    10741 gaaagtaacg ttactgataa cgttatggat aacgttacag taacgcatgg taacgcacta
    10801 gataaagaat tagataaaga tatagagata aataataata aggtgatgat tagttccagc
    10861 ctttctgaaa atttgaaaaa tagcggaatc catctaactg ataagtcaca tcaacagtta
    10921 cttgattatg tgggacttga tggaatgagt ttcgatatgt tgaaccgtgc agtcgagaaa
    10981 acttccggat cacacaaacc tagtttcaat tacctaatag ccattcttga aagttggaaa
    11041 aagaaaggct tcacatcgat tgagcaggtg gatgaggacg accgtaaata taaagagggt
    11101 aagaagtcaa gacaacaaaa cgataaaaca tcggaacagg aggtaaggga cgaatgggga
    11161 ttttagaact aattgagcag ttcgagattg actattatcc gttaagctac gagaagaaaa
    11221 ctcttttagc agaccaacca attcatccag tggttgcctg cttgtctgaa atggctagct
    11281 ggcatgaatg cggaggtcgg ctagtatggt agacaatgtg tttgaggaaa tcgccttatc
    11341 ttatcgtagg aatacagaac aacaagaaga gttctgcgaa aagcataaca tccctttgat
    11401 aaagatattg aggaccgaga gtgttgtatg tcgcatgtgt gaatctgagc ggattcatga
    11461 agaaaatcag gaaagagtga atgaactggc taatgctgag aatgagcgag agaggaaata
    11521 ctatcttgaa aagttctctc tttatgatga aattttgaaa aatgctactt tggacaattt
    11581 tgaaacacca accgaaaaag aagcggaaaa gctagctttt gcaaagagga tttgtcgtga
    11641 gtggtctgag ggtgctagga acaacattgt acttcaggga gaagctggaa ctggtaagag
    11701 tcatttggct tttgctatgg ttaaggctct atctgagtac acgaaagaga ttgctatttt
    11761 tattaacgta actgacttgc tgatgaagat taaagctgat tttagtcagg aagagtttct
    11821 ggtcaataaa attgctagtg ctaagttctt ggttttggat gatttaggaa tggaaaaaga
    11881 tagcgaatgg tcatttacta ttctctacaa tatcttgaat aagcgttcaa acacaatcat
    11941 taccacaaat ttgatttctg ccgatattca aaaaagatat ggcagacctt tcatgtccag
    12001 actaatgaag ggtgtagata aagaccattt gatggttttc aatgatttga caaacaagcg
    12061 aaagcaatat ttttagaata ggggtggctg atgtttattt taaagcatgg gacaagagag
    12121 gataagccgt ttctaaggtc tgcaattatc agtgtgactg gcttggatat ttcgtgttct
    12181 gaggagaaga aagccatgcg gtttatttct cgggcggcag ccttacaggt tagcaaggca
    12241 ttgagaggtt cctttgggaa cttctaccct gtcgaggtgg agtgatgtta gagctttatt
    12301 tcgtctacaa cgggcactgt aagtttttcc ttgggaggtt tgacaatgtc gatgatctca
    12361 ttgagcagat ggaagaccat cagtgggctt tctcagctat cactcatcca aggtttcaga
    12421 agcacattgg tcagcggacg acacgatttg actacggttc taaggattgt tactatttag
    12481 cgactttttc aggaggagaa aaaaatgatt gaacttatta aagaatttgg aatggctatt
    12541 ctgtggttat ttcttggcta tttagtcggg gaacgtgcag caagaaagga aaagaaagat
    12601 gatcaataac gttacatttt tagtgggagg taagaaacat ggttggagta acctatcagg
    12661 aaattcatct ctttgttgaa tttttgaaag agcagtacgg gcaaggtcgt ccagactata
    12721 ttgaagccct gaacgactta gacggtctgg tggaagtctc ctacagagaa gctattgaaa
    12781 gatttttaga agatgaagta cgataaacag gctgagattg acggactgaa acgcacgatc
    12841 gagcaaaacg aagagaagat aatcgagtat tcgaagccgt gcgatgcacg caagagacgg
    12901 attagagcgc tggagcgcga tttgttgagg aaaaagaata aagaattaag acggaaagcg
    12961 gaggagttgg aatatgatgg aagagttaaa gcaaaaagtt aatgaagtat acaactggac
    13021 ggtagaagac gggaagccgc aacctcccaa gcaagattta ccacaagcgg tgaaagaccg
    13081 ggcggactat ttttgggaaa tggcagaaga tggtatgacg tttatgggag cgatggaatg
    13141 catcttcgct gatgaaaagc ctacagacta tgatttggga gctactaagg gttggttgcc
    13201 aaaatctaag gagtttgatg attgggttgg ctattcgcca agcatgtctc agttagttat
    13261 tgcagtttat ttgatttaca gaggaagcga agatgaaact taatgaattg attaagaaat
    13321 ataaaaaact tgagggtgta tggaatgctg aaggagcaga actagttcgt caaatttttc
    13381 tgcaagactt ggaacaacta gataaaccgc aaccagtcaa agttccgcag tgtgtggcgg
    13441 aatatataga atttaaaaag aaaaacaatt ttcatgttta cggtcttgct tggcttaacg
    13501 gctacgaggt cgaaaaagag aagcggtatt ttgttaagat taaagggaat attaaagaaa
    13561 atatgttggt ttatggagaa cttttgaaaa ggtatttctt tacaaaaagc tttagtttag
    13621 acgatgttat atattcccac actcgtaaag aactagaagc cgcaaacttc ggctgggtgt
    13681 ttgattgccc aggtattgag attgaggagg tggaataatg ggagatatac gaatactaga
    13741 cgcttgttgt ggcagtcgta tgttttggtt tgataaaaat gagagtcata caactttcat
    13801 ggacatcaga caagaaaaat ttgaaataca tggaaaaagg taaacgtaaa ccctgacgtt
    13861 gtcggagatt ttcgtgatat gccattcgat ggtgaaacat ttaatctagt agtatttgat
    13921 ccgccacatt tgaaatgggc aggtcaaaac tcaattatgc gatcacaata tggccagctg
    13981 gataaagtta cctggtcgga agatttagcc aagggttttg aagaatgtat gagagttcta
    14041 aaagttggag gtactctagt ttttaaatgg tctgattgtc aaatcaacgt taaagaagtt
    14101 cttaaatctg taccttttaa accattgttt ggacaacaaa gaggtactac gcattggatg
    14161 acgtttatga aatttgagaa ggtcacagag agaaaggacg gcacgtttgt aaaagaggag
    14221 gatttggcat gataccgaaa tttagagtgt ggcatcatga attaggtaga ctgatgtcag
    14281 tcaaatgtat gttttttcag gatagcgaga ttgaagaatt tgagttaaac gatgctttaa
    14341 tgaatgatta cattacagct tatcctgatg aaatcgaact catgcaatca acaggactca
    14401 aagacaagaa cggcaaggag gtattcatcg gtgacatcgt taaatgtaca agaggatgtc
    14461 tccatgaagt atatttagaa aaagaatacg gtggtacatt cataggtgga atgcctgctg
    14521 tatacctaaa aggacttgga gatggatatg cgtggacgga atatgaggaa atcatcggca
    14581 acatctacga aaatccagag cttttggagg ataaataatg aacccagaaa taattgacaa
    14641 tataaacaaa ccaagccact accaaggtgc aaacggtctt gaggctatcg atgttgtgca
    14701 taacttcgtt gggagccttt ccggagcgtc tgctttcttt tggggcaacg caatcaagta
    14761 tatgttacgg tttcaaaaga aaaatggtct ggaagacctg aagaaagcta gaaagaatct
    14821 tgactggctg attgaggaga tggagcatga gtgaatacgc attgtatgaa ggcgacacct
    14881 ttattaccat ggggacgctt gcggaaatca gcaaagaaac aggaattgct gaacggtgca
    14941 agtatttcag agtttgccat cgaagatatc tgtacgtttt ttgggattga gatccaagaa
    15001 aggaaataaa agtcaatgaa caaaagaatt aagaagaaga tagctaaacg gcagatacaa
    15061 gaaaagcaag aagaattata caaacaacta cggaaattaa gttctgaaga aattgaagct
    15121 ataactaaaa tgattaatca ggcagtttct aatattcgca aggctttctc tcagatattt
    15181 gataacttgt ttacattttt gaaaaacttg gaggtggaaa ttgaaaaaat tgagcgacga
    15241 agaactcaaa acgttagaca gagaactttt caaatttcaa aacattcaac gcacaataga
    15301 cttaagaagg ctagaattag aaaccagaaa cccagatgct caaagtgggc caactgtagg
    15361 aataagcaaa cctaccgaaa ctatcgcaat cagaatcgca gatgatccga ctttaaaatt
    15421 tcttgaagga tttaaaggga ttattaacaa actcttaagc aatctagtcg aggaggacaa
    15481 agaaattttc aatctacgct ggagataccc tcaactgaga tgggaagaaa tagcagaaca
    15541 gaaattcatg agcaaagcta caatctatcg acgtagaagg attatcttag aacagtacgc
    15601 tataatgaaa ggtgagttgt aaataagatt gagacaaaag acatcttgaa gtctcacaaa
    15661 aaaagggcta ttatgatagc atgaacttct gaaaacaaaa acacaaatca catgttggag
    15721 ttatcctatt tttacagaaa agttgtttaa cagaggaaca tcatgagtca gcaaccagct
    15781 ggctttttgt tttgtagaaa ggaggcagtt atggaatttg tatcaccgat aaaagacaat
    15841 gataatattc aagctatgaa agattatctc agagaatgga atgagatgta ttatatgcta
    15901 ttcatcacag gcctgaatac tggcttacga gtcggagata tacttacctt gaaagttaaa
    15961 gatgttcaag gttggcacat caaactgaga gaacggaaga ctggcaagca gataacaaga
    16021 cggatgacaa aagaactcaa gaaagaaatg aggagatatg ttgaaggcaa accatttcat
    16081 catttcttat tcaagagtag gcaaggtcag aataaagcga tcactcgtga gcgagcctat
    16141 caaatcatac atgaagcagc tgaagaactt ggcattgata atgttggcac acatacaatg
    16201 cgcaagacat tcggctataa atattacaac aagacaaagg acgtaggaac attacagaaa
    16261 atgttcaatc actcatcacc tgcaatcacc ctgagataca tagggataga gcaagcagag
    16321 cttgatgacg cactacggaa ctttgtcatt taatttttta gatattactt tcacataatg
    16381 agttaagcat aaactgaaaa aatgaaagtc ttcaaaacct atgattagta agggtttgag
    16441 atttagagtg agtttaacaa aatataagat atgtgaaagt gagggataaa attggtatag
    16501 ttacaagagg tgaaaaatgg taaaagaata ccgtgatgat tttcttggag aaaaggcctt
    16561 cgagaaatta aataaagata ttgatgccaa tcctgaagtt ggctttgaaa ttgttggata
    16621 tactcaaaca gcatttgtaa atggaatgca tataccgtta acagccatac tagtaaaatg
    16681 gaataatttt tttaaagaat cagaatgaga caaaagacat cttgaagtct cacaaaaaaa
    16741 ggtttattat ggtagcatag atttcttgta tgaggagggg ataggtcaaa ggcctatccc
    16801 ttttagcatt gagaaaggag gtttgagatg tataacaaac ctatcagacc atccttgaaa
    16861 tctaagaagt gggagaagtt ccgtgatagg ataatgcgta agcatgatta tctttgccaa
    16921 gaaagtttgc gttacggaat ttctgttcaa gcagaaatgg tacatcatat ctttcctgtg
    16981 tctgaatatc ctgagcttga atttgttgaa tggaattgct tgccattgac gaataagaaa
    17041 cataatacgt ttcatgatag agtgaacgat agagtaatca accaaggatt gtattggcag
    17101 aaaaaaagaa aaaaagaatt tttaaatttt ttcaaaaatg aaaaatgaaa atttttaatc
    17161 cccccctctt tttgaaaaat cattttggcc agtagggtac tggtgaaggg aactttttcc
    17221 aagtcggggg ccttcaaaca aaaagggggt aaaaactaag cgattttgac gaaaggaggt
    17281 agtttttggc taaaccaatt acagcaaagt cgattaagtc aaaagtggtc aagcagatga
    17341 aagacttggg aacttatcgt aaagagttcg aaatgatcat tgacattttt gcaggtatgt
    17401 tataccagta tcagaaactt gctcaagatt atgctgatat gggttatcca gtaacagaca
    17461 cctacgtcaa taaggctggt gctgaaaatg agcgcaaagt tccaatcttg acagcgatgg
    17521 aaattttgag gaaagatata ctcagctact ctaatcagtt gatgatgaat cctaagtcgc
    17581 tcggtgaggt agtagaacaa gagggtgagt cagttcttac tgaggtactg aagttcaaga
    17641 acgaaatcaa gaagaagcga gtgactggca atgggtaatc ttgataaagc taaaaaatac
    17701 gctcaacacg tcttaactca ccgagaagaa cattgcgaag aaaacatcct tgctgctgaa
    17761 cgttttttcc gtgatttaga aaatccaacc tttgagatgg atgaggatat ggtggatttt
    17821 gttattcact ttatcgagaa cgtgatagtt catcagcagg gcgatgatat gtttgcggta
    17881 tctatccgta acaagccatt gcttttgcaa ccgtggcaac atttcgttgt agttaatctg
    17941 tttggttttt actacaaggg tacgaatgag cgcaggttca aagaagcgct tatcatgctt
    18001 gctcggaaga atgggaagac ctcgtttact gctgcaatcg cacttgctta tcagatatta
    18061 gatacagata gcggttccaa atgctatatc gttgctaact cagtcaagca agcgatggaa
    18121 gcttttggtt ttttaagatt caacgttgaa cgctggaacg ataagaacat tcgtatcaag
    18181 gataataacc aagaacactc tatcaccgcc aattttggtg atgaaggttc tttctttatc
    18241 caggctttag cgaatgatga gagccgtctg gactctttga acggaaatgt tatcatcttg
    18301 gacgaagctc acacaatgag gaacagtaag aaacatggtc ttatgaaaaa aacaatgtca
    18361 gcatacagaa acagtatgct ttttgttatc tcaacggctg gggatattcc taccgggttc
    18421 cttgctaacc gtctgaaata ctgtcaaaag gtgctcaagc aattagtcac tgatgattca
    18481 tttttcatct tcatctgcaa ggctaatcaa tctgctgatg gggacgtggt gaactatctg
    18541 gacgagaata tcctcaagat ggctaatccg tcatggggtg tcacggtttc gctcaaggct
    18601 ctcaaggaag aagcagagca ggctatgaat gatcctcaga caagaaatga gtttttcaat
    18661 aagaccttga atatcttcac taactctatg aacgcttatt ttaatcctga tgagtttatt
    18721 gcgtcggata gttgctacga ttggagttta gaagagctgg cacgtttgcc tattcgttgg
    18781 tatggtggtg cggacttgtc aagattgcac gacttaacag ctgctgctct ctatggtgtc
    18841 tatcatgacg gtgagaaaga cgttgatatc tgtatcacac atgctttctt ccctcggatt
    18901 aatgctcaga aaaaagctaa tgatgacggg attccactct ttgggtggca gtctgacggt
    18961 tggttgacga tgagcaacac tccgaccgtc ctctatgatg atatcgtcaa atggttcatc
    19021 aagatgaggg agaaagggtt caagattgct gctgtcggaa tggataggaa gtttggccgt
    19081 gagttcttga cgaagatgaa acaagctcgg ttcaagatga ttgaccaacc tcagcttttt
    19141 tatctgaaat cagagggatt cagacggatt gagtttaaag ttaagaataa agaattttac
    19201 tatcttcatt ctgatgctta cgaatactgt gtgagcaatg ttagagcaat tgaaaaggtg
    19261 gacgatgctg tgcaatatga gaaattagat ggagacggtg ggactgcaag gattgacttg
    19321 tttgatgcca gcgtctttgc ttgtatacag gctcttgcta atcttggcaa gggtggtgat
    19381 gtgatgagat tctttgatta ggtgaattat gaatgaaata gtattatcag aacatgaaat
    19441 taacttgctg atcaacaaag ggcgagttaa agtaatttta aacggggaag tagtaactat
    19501 tcgtcaaaga catatgaaaa atttgatggc tgaaacagta aaatgggaaa aacaggtaat
    19561 tgatgtcagt cagaatatcg taagaaataa acactttgat tcactttttc aaaatacttt
    19621 tcgttagaaa ggaggtgagg aaacatgggt atttttgaaa agttttggaa acgaaacaag
    19681 ccaagtaagt caatcaacat gctgagtcat tcagatttag ggttgtcaaa cctgatggac
    19741 tcgtatgtac ctttggccag aaatccagat gtggtgacag cggttaataa gattgctgat
    19801 ttggtctcta atatgaccat ccacttgatg gagaatacag ataaaggtga tatcagaatc
    19861 cgtgatgggc ttgctagaaa gattgatatc aatccgtgta aacacatgac aaggaagtca
    19921 tggattttca agattgtgcg cgatttgctt ttatatggcg atgggaactc tgtcctacat
    19981 gtggaatatg aacctgttac ggattatatt tctaatctaa gaccatttcc gatgagagag
    20041 gtttcattcc aaacagataa ggattcctat gtaatctcat ttaggggtga agaatattcc
    20101 cctgatgaag tagtccactt cgtcatcaat ccagatccag atattccata cattggtact
    20161 ggttttaggg tgacgttgac agatgtggtt caaagtttga acatggctac caagactaaa
    20221 aaaagcttta tgaacgggaa gaatattcct agtcttatcg ttaaagtaga ctcgtctagt
    20281 gctgaactag attcggagca agggcgtgag cgtatcgctg agaagtattt gagtactagc
    20341 agggttggcg ctccatggat tgttccagag gcattgctgg acattcagca ggtaaaaccg
    20401 cttagtctaa cggacatcgc tttaaacgag tctgtggaat tggataaaag aacagttgca
    20461 ggtctattag gagtacctgc ttttattttg ggtgtaggag agttcaacaa gacagagtat
    20521 aacaactttg taaatacgac tgtcatgagt attgctacca ctattactca aacactaacc
    20581 agggacttac ttttgtctag caatcgttac ttcaagctaa atcctcgttc actcttctct
    20641 tacaacatta cggagttgtc tgctgttgct caacaaatgg caaacagtgc tgcaatgcgt
    20701 cgtaatgagt ggagggattg gctagggatg gctcctgatc ctgagatgga agagttgatt
    20761 gttcttgaaa actttctccc tcaggagaaa ctaggagatc aaaataaact gaagggaggt
    20821 gaggaagaga atgcaaaagc gaaatagcta tcgtgccact caatttcaaa cgagagaaga
    20881 agaatctggt gatttgattt tgagtggcta ctttatcaag tttgacgagg agacggaatt
    20941 gtggccaggc tactgtgaag ttatcaagcg tgctggtgtt gagaaagctg tcacagacgc
    21001 tgatatcaga gctttattta accatgatga tagccttgtt ctcggtcgaa caggtaacgg
    21061 aactctgaca ctgggtgttg atgatgttgg tctttttgga gatatcatca ttaacaagga
    21121 tgatcctcaa gctgttgggg cctatgcccg tgtcaagcgt ggagatgtta tagggtgtag
    21181 ctttggcttt atcccggtaa aaatcgaaac ggaagaacgt gaagatggtt catatttgga
    21241 cactgtctta gagctagaaa tctttgaagt gagtccatgt actttcccag cctatccaca
    21301 aacggaaatt gctgcacgac aaaaagactt cgaaagtcag aagcgtgcta atcgtgaagc
    21361 gctagacaag cgcaagaaag aaattaagga gaaatttaat ctatgaacaa attattgatt
    21421 ttgggcgctc gtatgcgcaa caaagcagac aaagttgtag agcttgaaga atcaatcaaa
    21481 gaattgaaca agcgttctga acttgaagct aagaaattgg aacaagctgg aactgacgaa
    21541 gaagtttcag cagttgaaaa gaaccttgaa gacatccaaa aagaatcgga tgaaaaggaa
    21601 gcagaaaaag aacaacttga aaaagaaatc gaagatttga aaaatcaagt tgaagaacta
    21661 aatcgtaaag caccgactta cccaagtcaa gaaaaacgtg gaggacagaa attggaacga
    21721 cgtgacgcaa tcgctaaata cattcgtact ggtcaaactc gtgacattgt aggcttgaaa
    21781 actactgatt caggaagcgc agctttaatc cctactgaag ttttgaaacc tcattttgtt
    21841 aataaaacac gtaatccact tttggatctt gtggaacgtg tgaaagttaa tagtggatct
    21901 ggtaaatatc cagttatcaa gaaaacggat ggtgtaatgg tttcaataga tgaattgaaa
    21961 tcaaatccag aactcggaaa accagcaatc agcgagattg attattcaat caagacttac
    22021 cgtggatatg tccctgtgtc acaagaaatg attgacgacg cagactatga catcatgtcc
    22081 attgttgaag acgaagtgtt caatcaaggt gacaacactg aattgtcatt agttacagct
    22141 gtcctcaaaa cagctaccca agcagatgcg gctggatttg atggtattaa agatatctac
    22201 aacaagaagc ttaaatcaat ttataaagca agcatcgttg taactaagtc aatgtttgct
    22261 gcgcttgaca aagtgaagga caaagatggg cgctacatgc ttcaaactga tgtggcttca
    22321 cctactggct attcatttgg tgggaaaaca atctacaaag tagatgacac agtgtttgga
    22381 aacgaaggag atatgaaatt cttcatcgga gatgttactg agttcgtcaa agagtttgac
    22441 cgttctcaag tatccgttaa atgggtgaac aatgacattt acggacaatt gcttgggctt
    22501 tttatccgtt tggatattaa gaaagcagat gaagaagctg gattcttcgg aacatatact
    22561 gatgttgtag cttaaggagg tagcgtatga gctataaagt aatccgtcct ttcaaggact
    22621 tggctgatcc tgaaaatcat gactacgctg ttggcgatat ctttcctcgt gagggatatg
    22681 agccaacaga tagctttacc aatggccttt tgactggcgc taacactgct ggctctatct
    22741 tccttgaggt tttgggagat gatgaaccta agaaaccagc gcctgaaaca aaagaagtga
    22801 aggaagagcc cgcagttgag caggaagaaa cagttgagga aactgctgaa gagtctgctg
    22861 aggaagttga ggaatagaca tggaccaagg tcagctttta gagttgctga agcttaagtt
    22921 gggtatttca accgacttga gagacaagcc gttaaaaaaa atcatttcaa gtgtcatcac
    22981 tgaattgacc gataatctcg gtatcgagct tgttggtgag cgtgctgacc atgaaatgtt
    23041 tatcgttgac tatgccgctt atcgttatga gggtggggtg gatatgccac gtcaccttca
    23101 gtggcgactg cataatttac agatagcatc aaagaaagag gtcaagaatg tggaatcatg
    23161 aaatcacact gatctccaag aaagtaacag gtaaggataa gttactacaa ccaatctctg
    23221 aagatgttga agttactctc ttatgtcgca aaaagagggt cactcgctct gaattttatc
    23281 aggcgaatca ggtagggctt aaaccgagct tggtcgttga gattcgaaat tttgagtatg
    23341 agaatcaaga gcttgcgaag ttcgaaggca agcaatatca tatcttgaaa acctatccta
    23401 ttgattctga aattttagag ttgactttgt cagaggtgtt gaaatgagta atgaccttgc
    23461 tgatttgata gcgaaagagc ttgcagctta ctctgatgag gttactgaag aagtggataa
    23521 gattgcagag caagtgactg atgagactgt ggatgagttg aaagagacaa gtccgaaacg
    23581 gtacggaaag tatcgtagaa gttggaaaaa gaagaagttg gccaatggct cttttgttgt
    23641 gttcaacgca gttgcaagtc ttactcacat acttgaaaac gggcaccttt caagaaatgg
    23701 tggtcgtgtc gctggtatcg tccacatcaa gccagctgaa gaaaaagcaa ttcagaactt
    23761 tgagaagcga atcaaggaga ttgggaaatg aagctatcag actttgctgc tattttggaa
    23821 caggcaaact tgcctgtcac ttatcgagcg tttaaaattg gaaacgctcc tgacctacct
    23881 tatctggtct attatgaatc aagtccagtc atcaattcag ctgacaacac ggttaatcat
    23941 cagattaaga gcgtgacagt tgagctggct tttgagagta aggatgaaga tttggaagaa
    24001 cgtctggaag agctgtgggc aaaccacaag ctcttttttg aagttcaaga agaaacattt
    24061 atcgagactg aaagactcta tgtcaagtct tacacagtct atctatacta aggaggaatg
    24121 acatgactca agaaaataaa gtaacctttg gcctagaaaa tgtacatatc gcacctatca
    24181 agacacttgc agcagatgga gttatcactt acggcgatgt ttttcgtttt cctggagcaa
    24241 tagagctgat acttgatact aaaggggaaa caacccctat caaagcagac aacaaggatt
    24301 accatttcat gaattcaaac gaaggatatg agggtaaact taaaatccca cacatcattg
    24361 atgaatttgc gacaaaaatt cttggtgaaa tcaaggaccc tcaaactggt gttatgactg
    24421 aaaaagcaga tgcgagcttg acagagttcg caatgatgtt ccagtttgaa ggcgacaaaa
    24481 acaagactcg ctatgtgatg tactactgtt ttgccagtcg cccatctctt ggctcaaaaa
    24541 ctaagaacgg gacatcaacc aacgaacgtg aacttagttt caaagctagc ccgcgtccat
    24601 tggatacagt tgtcaagcgt tctatcacat cagctgatga caaggatgcg tatgacaact
    24661 ggttcaagaa agtgtatgaa cctactgcag ttgcagctta aggagaagat ctatgcgtaa
    24721 aatcgttttg gttggtgatc aggagtatga gttggggacc aacggctata ctcctattgc
    24781 ttacaagcaa caatttggaa aagattattt tcaagatttg ttctcgatgt tgaaaaatca
    24841 atcattcatg aatgaattga acaagttgga aaccgacaag gaattgacag cgactaatat
    24901 tgatatttcg atgttgtcag attttgacat gacctttttc aaccgtcttt tttggacctt
    24961 tgctaaatct gcaaatcctc acatcaagcc ttatgaacaa ttcttcatgg aaatggaaat
    25021 cttcccgatt caggaagttg gacctgtgct gatggaaatg ctaaatgcga gcatgacgac
    25081 aaaaaagcac cagatgagtc agaatcagct agcgaagaaa tcttcacagt agaatcctat
    25141 ctatcttgct gtaaagaaac tggtctttct attgatgatc taaagcacat ttcaatcgga
    25201 atggctctgg attatcagac ggattatgtg aatctacgga gcgaggataa gggtggcgaa
    25261 cggaaagcca cgcaagctga ttttgacagt ttttaaagaa aaatgagtgc tgagagagcg
    25321 attctgagac caagttcctt ggtctggctg cattatcagt ggtagaagtt ctctcagcgc
    25381 ttttctattt ttttgagaaa ggaggaaata tggcaggaaa tatcaaaggt atcaaaattg
    25441 aaatcgatgg cgacacgcaa cccttgcaga aggcgctgaa aaatgtcaat aaggccgcta
    25501 ctgatgcaag tcaggagttg agacagattg acaaggcctt gaaatttgat acagggaacg
    25561 taacgctcct gactcagaaa caagaggtct tacaaaagca agtttcgacg accaaggaga
    25621 aactggaaac cttgagacaa gctcagtctc aggtggaaca gcagttcaaa aatggtgata
    25681 tcggtgctga tcagtaccgt gcctttcaac gcgaagtcga agttactcaa aacgtcctaa
    25741 aaggatatga gggtaagctt gcaaatgtga atcaggcgct taatgagaat gggagtgcta
    25801 ctcagaacaa caagaaccaa ttaaaagagt tgcaaaatga gcagagtcaa cttgcttcag
    25861 agatgagtaa ggtgacaagt tcattcaaac tgcaagaaag cgctttgggt tcaaatgcta
    25921 gtgaagccga gagaaatgct cttgcccaga aaaagattgg tgcccagtct gagattgtaa
    25981 gtaaacagat ttcaaatcta gaacagcaat tggaaatcac taaaaaagaa tttggtgaga
    26041 actccacaca agccaacaag atggaatctg agctaaatca ggctaagact gcttttaatc
    26101 atctcaatga tgagatgaag ggaacaaagt ctgctgctga tagcactcaa gaaagtttaa
    26161 gtgaaatctc aagaaattta agagcagaac tacttcaaca gtttagtgag aagttgagtg
    26221 ctatttcaga aaagcttgtg gaagtaggaa aagaagcgtt agaagcagct gctcaaatgc
    26281 aagctagtaa tgctcaattt actaccgttt tcggagatat ggaaacccaa gcaagagaag
    26341 cgttgaatgc tattggtcag gaaatggata ttgtcccaga gcgtttacaa gggtcattta
    26401 ctcagatggc ttcatttgct aaaacttcag gactagacac tgcgcaagca ttggacctga
    26461 cttcccgtgc aactagggca gcggcggatg gcgcagcttt ttacgacaag tccatcgaga
    26521 gcgtatcaga aagcctacaa tctttcctga aaggaaactt tgctaacgat gccgctcttg
    26581 gaatctctgc gacagaaacg accaggaatg cagctgcaaa taaattgtac ggaaagtcat
    26641 tcaaggactt gagcgaagcg cagaagcaat tgaccttgct tcagatggtc gaagacggaa
    26701 ataaactctc aggagctctt ggacaggctg caagagaatc agacggccta gaaaacgtga
    26761 tggggaatct gaaacaagct gggaccaatg cattatctgc tattggtcaa cctcttctag
    26821 aaatgatgat tcctgttttt caaaccttgg caacgattgt gaaaggtgtg gccgagctgt
    26881 tcaattcctt gcctgatcca gtaaaagatt ttgttgttat tttaggaaca gttgtgactg
    26941 ctgtaggggt catagccccc atattcttaa ccttgcaagc ccttgctgag tttttaaaaa
    27001 tatctattgg agaaatgata attgccgcat tgccaattat tggaacagct attgcaattg
    27061 ctgctgcagt tgctgcaatt attgttattg taaaatatct ctgggaaact aacgaaggtt
    27121 ttcgagatgc ggtcacgacc gtttggaatg ctatactagc cgttatcaat acagttgttt
    27181 cagaaatctc tgatttcatc atgagtatat tcgggacggt tgttacttgg tggacggaga
    27241 accaggaact tatcaggaca agtgctgaga ctgtctggaa tgccatttat acggtcatca
    27301 gtacaatact ggatatactt ggccccttgc tccaagctgg ctgggataac attcaactga
    27361 tcattacaac aacttgggaa atcatcaaga tcgttgttga gactgcaatc aatgttgtcc
    27421 ttggtgttat ccaagcagtt atgcagatca ttactggtga ttggtcagga gcttgggaaa
    27481 ctatcaaggg agtgttttct actgtatggc aagctattca aagcattgtt cagactattt
    27541 tctcagctat ccagagttat atttcaaata ttctcaacgg catttcagga actgtatcaa
    27601 atatctggaa cagcatcaag gacactgtct caaatgtgtt aaatgctata tctagtactg
    27661 tatcaagtgt ttgggaaggt atcaagagta ccatttcaag tgctatcaat ggtgcaaggg
    27721 atgctgtttc ttcagctatt gaagccatca aaggattgtt taacttcaac atcagctggc
    27781 cacatatccc actacctcac ttttacgtga gtggttcggc caatccatta gattggttga
    27841 gtcaaggtgt tccaagtatt ggaatcgaat ggtatgccaa aggcggtatc atgacgaaac
    27901 caactatctt tggaatgaat ggtaataaca taatggttgg tggtgaagct gggaatgaag
    27961 cagtattgcc acttaacgac aaaacgcttg gagccatcgg tcgaggtatc gctcaaacta
    28021 tgggtggaac ttcaccaacc atcaacatta ctattactgg taacaccgtc agagaagaag
    28081 ctgacatcag tcggattgct gatgaggtgg ctcagcgtat tgctgacgaa ttacaacgta
    28141 ggagacaatt gagaggaggg tttgcatgat aaagcataat gagcttgtga ttgacggtgt
    28201 gaggacatcg tcttttccat ttaagatcat tgtccatgac tctccttcaa tcgctctagg
    28261 agagagcaag acagctctct tggagcatgg tggtgtcagt ggggcaatcg ttcagacaaa
    28321 caagcatagg gaactggtca agaaaactta tacgatttac ttggtcaaac ctactgaaga
    28381 acagatgaac caatttatga gtctgtttat ccgtgaaaag ttctggctag agagtgagcg
    28441 agtcaaaaca actcgtcttt ggtgctataa ggtcaatgtg agcgaccttg aagaagtgca
    28501 acctggtctt tacatgacca aagcaacctt cacttgccat cctacaaaat actttaaaga
    28561 ctccgataca cagagattga caagaagtgg gactttgacc gttcaaggtt ctgctcttgc
    28621 ctttcctaaa atcacaatcg ttggtcagag cgcttctgaa acttcattta caattgctgg
    28681 tcaggtcatt cgtcttgaac gactcactga gtcgcttgtg atggttaata atcctgacaa
    28741 tccaagtttt aaaacaacaa cagggaagcc agtcaaatgg tcaggggatt ttatcacagt
    28801 tgatccagcg aaagtgaaga atattggggt tgttttaggc ccaggtattc aatcgattga
    28861 aatcgaaacg gtttgggggt gggcataatt gctttatcta cttaataaag atgtaagaac
    28921 cgttcgatgg aacggggagc cacttcatga agcgacttcg gcgattgtga aagaaactat
    28981 gaatggcgat tttaccttga ctgtgaaata tcctatttct gattctggta tttaccagct
    29041 catccaagaa gatatgctga taaaggctcc gactcctgtc ttaggagcgc agctatttcg
    29101 tatcaagaaa cctgttgagc acaatgacca tctggaaatc acagcctatc acatttcaga
    29161 tgatgtgatg caacgatcta tcacacaaat gagtgtgact agtcagagtt gtggcatggc
    29221 tcttgctcgc atggtacaaa acaccaaaac ggctcttgga gacttctcat tcaacagtga
    29281 tatccaggac cgtaggacat tcaacacgac tgagacagaa accctgtact ctgtattgct
    29341 ggacggcaag catagtatcg ccggaacgtg ggaaggcgag ctggtgcgtg ataactttgc
    29401 gatgactgta aagaagagtc gtggtgagaa tcgtggtgtt gttattacaa cacataagaa
    29461 tctgaaggac taccaacgaa ccaaaaacag tcaaaatgtt gttacaagga ttcatgctcg
    29521 atccacattt aagcctgaag gtgctgaaaa ggaaacaact atcagagtga ctgttgatag
    29581 tcctcttatt aattcttatc cttatataaa cgaaaaagag tatgagaaca acaacgcaaa
    29641 atccgttgaa gagttgcaga agtgggcaca gtctaagttc tcaaatgagg gaattgacaa
    29701 ggtctctgat gctatcaaaa ttgaagctta tgaacttgat gggcaagtgg tccatatggg
    29761 cgacacggtc aatctcaaga gctggaaaca taatgtcgat gcattcaaga aagctattgc
    29821 ttatgagttc gatgccttaa aagaagaata catctctctg actttcgatg ataaggcagg
    29881 tattggtggt tctagatctt ctggtggcct atctagcgca gccgatgcaa ttcttggagt
    29941 gacagaatct gcacaagaaa tcgcccttga aaaggctctt caaaatgctg acttagactt
    30001 tgatcataag gctggattgc ttagacagga aatttctgac gatattgaac tggccaaagc
    30061 cagagctgaa gaagtcaaga gagaactgtc tgacactatc aatcagcgat ttaatagctt
    30121 tgacaacggg ccattgaaag aaactaagcg caaggctgag gaagctttgc gaaatgctgg
    30181 cgcaagtacc ctgcttgcac aggaagctaa gcggattggg ctggattctg tcgctagact
    30241 tgaagcgttt aagtcgcaga ctacgagcgc acaaacggct ctgtcgggtg acttggacgc
    30301 tctgaaacgg actatcgcga atgatattcg accgaagcaa gcacaggctg aagctgagat
    30361 tgccaagcaa gctgaagcac ttagccggac taaaaatgaa ctggctggcg caagtaccct
    30421 acttgcacag gaagctaagc ggattgagct ggattctgtt gctagacttg aagcgtttaa
    30481 gtcgcagact acgagcgctc agacggcttt gtcaggtgac ttggatgttc taaaacaaac
    30541 tatcgcaaac gatattcgac cgaagcaagc acaggctgaa gctgagattg ccaagcaagt
    30601 tgaagcactt agccggacta agaatgaact ggctggcgtg aagtcagcgc aagcgacgta
    30661 taaggagacg acgactcgta gactgtcaga actgaccaac ttggcaaatg gtaaagccag
    30721 caagtcagaa cttacgcaaa cagctgagga gctggctagt cggattgcga gtgtgcaggc
    30781 aggtagttca cggaattact tcaggaattc acgttcaaga acgttcacaa caggaggtca
    30841 agcggtatac gactatcgaa cattcatagt tcctgatttc tggaagaaca gtgacaggtt
    30901 caagcgtgat tatgttcgca tatcttttga tgtgactttc cctgtcgccc tagtaaatga
    30961 catgcctgct atggtgcatt ttagtgctca tccatggtat gcctacagaa acttaatttt
    31021 taaaggtgga actgtcgaac gccaacattt tgagtttacg attgacttgt ctagttcttc
    31081 tgaggactat cagactaata atgtgttcat tcgttttggt actaattatg gatttcctgc
    31141 tggtctgcag gtcgtcattg agaacgctat gttatcggtt ggtaattatt ttccagccta
    31201 tcaaccagcg tatgaagacc aagaagaccg tgtctcagta gtcgaatcca actttaaaca
    31261 gcgtgctgat tcactcgacg ctggtgtaag aagcttgact gaaggcctta gaaccaaagc
    31321 ggatatcagc tcactcaatg tgactgctga aaatatccgg caatctgtga agagccttga
    31381 gacagatacg cagaacaagc taaatcagaa gttgagtcag gctgaatttg aggtgcgagc
    31441 cggctctatc cgtcaggaaa tcctgaacgc aaccaaggat aaagccagca agtcagaact
    31501 cacgcagaca gctgaggagc tggctagtcg gattgcgagt gtgcaggcat ccggtcgaaa
    31561 tctattcttg aactcactat tcaagcagga tattccaaaa acaggaattt ggacaacgag
    31621 tacatatacg gctactatcg atagcgaaag taagtatctt ggacacaagg ctcttaaaat
    31681 tataggtttg aatccatctg gccgtgatgg aggtaatccc aaggttactt atccagctct
    31741 gggtcaattc gggaaagtaa ttcccggaag tacgactaat caagatgtaa ccattagttt
    31801 ttatgctaag gcaaataaaa atggaataat gctaagatct cgattaggga atatcggata
    31861 taaaactgga aatgtgacat tgtcgacaga aattaagcga tatgttgtcc atattccaaa
    31921 aggttggaca aacgaatcca agcagaccac aaatgaatgg ttgttcaatt tcaaccagga
    31981 aggaaccatt tggatttgga tgccgaagtt tgaaataagc gatgtagata cttcttattc
    32041 agaagctcct gaagatatag aaggtcagat ttcaacagtt gaatcgacct tcaaacaacg
    32101 agccaactaa ctcgacgctg gtgtaagccg tctgactgaa ggccttagaa ccaaagtgga
    32161 tatcagctca ctcaacgtga ctgctgaaaa tattaggcag tcggtgaaga gtcttgagac
    32221 agacacgcag aacaagctaa atcagaagtt gagtcaggct gaatttgagg tgcgagcaag
    32281 cggaatccgt caggaaatcc tgaatgcaac caaggacaag gctgacaaga ccttggtaac
    32341 agcggaggct gggaagttga gagaggagct gacaagtctg tcggttggcg agaatctgtt
    32401 tgtaaactca gattttaaaa atctgaggga taacggacag cgttatacag ctaacggcaa
    32461 gacctatcaa aacatgattg cgccttactg gtacaatccg tacaatgctg gtattccaaa
    32521 tgctcaaaat atccagcatg ggtattttga cacggaaacg tttagtgata ctgtctttgc
    32581 ctttaacgag agcgacggct cccgacactg gaaagcattg tcaactgatt ttaaaatcgg
    32641 agtcatctca gctggagagt attacttttc agctgatttg tatgcgacag atttaggcac
    32701 tcatatcaaa tttggatttt actatcacaa ctcgactggc aaactcaatt tttacgcagg
    32761 tcgaacaaaa attgaagtta ctgaaaaagg ccgttggact aggctaggaa ttgacttaaa
    32821 ggtcaatgat gacattgacc tgacaaaaaa agtccaattt tacatttacg gctataattt
    32881 tgctagcaac tcaattttgt accttaaaaa gcctaaagtc tcgaaaggtc gcttaaaaag
    32941 cgattggagc ccagctctgg aagacaccga aggcctcatc actgaggcta aggcaacctt
    33001 tgagcggaca gctcagggct tgcgaaccga cttatcagct attcaggaat atgtaaataa
    33061 agacggtcag cgacaggaag ccctacagcg ctatactcgt gaggagagca cgagacaagc
    33121 gacagcagtc cgtgagctgg tcaatcgtga tttcgttggt aaggctactt atcaagaaga
    33181 tgttaagggt atcaatcaga ggattgaagc tgttaaaact agtgcgaata aagacatcgc
    33241 tagtcaaatc gctagctatc gtcaatctgt agatggtaag ttcacggata tttcaagtca
    33301 gataactact tataagcaag atgtgggcgg tcaaatcagt ggtctatcaa atagacttac
    33361 aagcagtgag caaggaacca ctactcagat ttcaaatatt tcaaatcgga taaacagtaa
    33421 taaacaaggc acagataatc agatttcaaa tttaaagact caggtcgcta caaacaagga
    33481 taatgctgaa cgacaaatgg gtagaatatc tgatcaggtt tctgcaaaca aagcgaatgc
    33541 tgatagtcaa tttgcgaatg tgaccaatca actagcgcga aaagtagaga ctactgactt
    33601 ccagcgtgtt aaggaaacca gtaaacttta cgagcggatt ttgggcaata ctgaaaatgg
    33661 aattgcggat aaggttgctc gcatggctct gaccaatcaa ctgtttcagg ttgaggttgg
    33721 gaaatatagt gtaagcggcc ctaacctcat taagaatagt gattttaaaa atggtacgaa
    33781 tgaatggggc tcaactcaaa atttaggaag attggttaag catagctttt atcacaacgg
    33841 gcagaaagac cttatgcgtt taagtaatgc aactaaaaac gaaaactttt tgtatagtca
    33901 ccgttttaat cttgaacgaa atactgacta tgtactgaat tttagaggat ttaacaacag
    33961 tgctctcgca agctatgatg tttatatttt gggacgaaga gcaggcgaga gcgatggatt
    34021 cacaatcgtt aagaaagttg ttagcagcaa gaaactatct acctctagat gcgaagatgt
    34081 ctcagtaact tttaattccg gagaaatgga taatgcttac attcgttttg ataacaatgg
    34141 ctcatcatca ggaacagctg atttgtatat tacagaagtt gacttgtaca aaggttataa
    34201 acctagaaca tggcaaccac atccagaaga tgcagtcgca gatgcgaata agaagcttga
    34261 agccacgcaa acaaaaatga ctcaactagc tggctcatgg gtagttgaaa acatcaactc
    34321 ggctggagat atcatctctg gaatcaatct tggcgccaat ggacataacc gctttgttgg
    34381 gaaattgacc cacatcactg gagagaccct gattgacaga gcagtcatca agtctgccat
    34441 ggttgataag ctcaaaacgg ccaattttga agctggttcg gtcacgacta cgatattaga
    34501 cgctgaagcg gtcacggctg ataaagtgag atttgatgct gcgtttatta gaaaaatgat
    34561 tgcaaatgac gcttttattg accaactgac atctaaacgt atcttctcta ctaaggttga
    34621 gtccgtcatt tctagttcaa ccttcctaga agcctatcaa ggccgaatcg gtggatttac
    34681 acttggtcaa tttgatcagg gtggcggtcg ctggatttca ggtgtcaatc agttctctgt
    34741 tggtatgggg aatggtgccg ggcatggggt gccggacagc cttctgggcg aactggggaa
    34801 ataattggaa ctatgccgga cctaaagcat ggaacgtcaa tactgatggg aaaatgtact
    34861 gtaggaatga agtcggtttt tatgatcaag tggatttttc gaattcatcg agagcaaact
    34921 tctatgggaa tactactttt tctcgttctc ctgtgttttc aaatggtatc gaacttggaa
    34981 gtaaagatgt gcttggtgat ggttggaatc ccaaaggcgg aaggaatgcg gttgtttggt
    35041 ggaatcaggt cggtagcggt agcgtgaagt attggatgga acaaaaatca gacagacgct
    35101 taaaagagaa catcacagat acagctgtga aagccttgga caaaatcaac agattaagaa
    35161 tggttgcatt tgatttcatc gaaaataaga aacacgagga gattggtcta atagctcaag
    35221 aggctgaaac catcgttcca agaattgtct cacgagatcc tgagaatcca gatggctatc
    35281 tacatatcga ctataccgct ttagttcctt acttaatcaa ggctattcaa gaattaaatc
    35341 aaaaaataga aaaaatggag aaaacaatag catgaataac aacatgttga ccaatatcgc
    35401 acttaaagca attcaggagt ttgctcttga aaatagaaaa cgaacacaca gattggagaa
    35461 cttagaaaat gaacacagaa cagcttaacc aagccttaca aatgacaatt cgtgaaatgt
    35521 caacaacttc aacagattcg atgattgcaa gtaatttctt gagtattcag ttgaatgagc
    35581 aaagggaaga gaatcaaaga cttcaagcac gagtggatga gctggaagct ctgcttgatg
    35641 aacaaactaa accagcagac aaaggagaat agacatggca gaaacaattc aaaacacaga
    35701 taacttacta gaccttacaa aaatcacaga accatttgat cttgcgagcg ctttgcgcta
    35761 catgaaagaa aatggagagt tcattcgttg caagaatgta agcgatgact tctatatgta
    35821 tcgtgatgtt caaaaacgtc ctgtgatcgt aaatggccgt cgccaattca aggatgttga
    35881 aactgtttgg gcgttcaacc agtggggggg ggtacaatca caacaatcaa cgtagccgtt
    35941 ctgttgaatc atgaattcta tatcatgaaa tttgatgcag agggcaatcc tgactggacg
    36001 gatccaacgg taaaacctaa agaataggag gtgtgtatgc aaattgaatt tttcaatttt
    36061 ctaagaagtg tcgtacagac tgaagatggt ttggtcttgt acgctctagc actgattgtc
    36121 tcaatggaaa tcattgattt tgtgacaggg acgattgcgg cgattatcaa tcctgacatc
    36181 gagtacaaga gcaaaatcgg cattaacggg ctccttcgta agatttcagg ggttctctta
    36241 ctgatgatcc tcattccggc gtccgttttg ttgcctgaaa agacaggttt tgtattcttg
    36301 cactcaatct atctcgggta catcgcattt acttttcaat ctctcattga aaattaccgc
    36361 aaattaaaag gaaatgttac tctttttcag ccgattgtaa aagtatttca gcgattactt
    36421 gaaaaagatg atgatacgaa aaaaggagaa taacaaatgc aacaaattac tgaaatcatt
    36481 actaatggag caatcagcat cctagtcatt ttggcagggg tggtagttag ggtagtcaag
    36541 gaatacctcg tcaaaaaagg tggagaaaag actatcaaga ttgttgaaat cttggccaag
    36601 aacgcagtta atgccgtgga gcaggtagct gctgaaactg gctacaaggg agatgaaaaa
    36661 ctggcacagg ctcgcgctaa aattcgtgca gagctgacca aatataatat cagtatgacg
    36721 gacaaggact tggacacctt tgtggagtca gccgtgaagc agatgaacga cgcttggaaa
    36781 ggacaagagt aatggatatc gatagaaaca gactacgtac aggcttgccc caggttgggg
    36841 tgcagcctta tcgacaagta catgctcact caacaggcaa ccgtaactca accgctcaaa
    36901 atgaagctga ttaccactat agaaaggacc ctgaactagg gttcttttca catgttgtcg
    36961 gaaacggccg catcatgcag gtaggacctg tgaacaacgg aagttgggat gttgggggcg
    37021 gttggaatgc tgagagttat gcagcggttg aactgattga aagccattca actaaggaag
    37081 agtttatggc tgactatcgc ctctatatcg aattgctacg caatctagca gatgaagcag
    37141 gtttgccgaa aacgcttgat acagggagtt tagctggaat taaaacgcac gagtattgca
    37201 cgaataacca accaaacaac cactcagacc acgttgaccc ttatccatat cttgcaagtt
    37261 ggggcattag ccgtgagcag tttaagcaag acatcgaaaa cggcttgagc gctgcgacag
    37321 gctggcagaa aaatggtact ggctactggt acgtacactc agacggctct tatccaaaag
    37381 acaagtttga gaaaatcaac ggtacctggt attatttcga tggctcaggc tatatgcttt
    37441 cagaccgctg gaagaagcac acagacggta attggtacta ctttgaccaa tcaggcgaaa
    37501 tggccacagg ctggaagaaa atcgctgaga agtggtacta ttttgatgta gaaggtgcca
    37561 tgaagacagg ctgggtcaag tacaaggaca catggtacta cttagacgct aaagaaggcg
    37621 ccatggtatc aaatgccttt atccagtcag cggacggaac aggttggtac tacctcaaac
    37681 cagacggaac actggcagat aagccagact tcacagtaga gccagatggc ttgattacag
    37741 ttaaataaat agaaaggaaa ctttctaaat tgttctttca ccgcaggctc aggcttgcgg
    37801 tttttttgtt tgtctgaatc aagaaagcgt ctaaccaacc gacaccaatg tcggtagcaa
    37861 aataaatggt ttgcctaaaa aattagagtt aagttctatt tttcaaaaac acgcattttg
    37921 aacgattaga aacagaaatc taaatcctat tgttcaaaaa aacgtttaca tgaaaaatag
    37981 ggaggtgttt tgttaaaaat aaaaacagtg atcgaaatca ctgcttatca gttgtagcaa
    38041 attcataaag tttttctgct gtgagaagtg ccattttgtc catgcttgtt tttccttttc
    38101 tgaggtcaga aacagtagtc catggaactc cagcaccttg ggaaatagca gatgtagaca
    38161 tcgaactgtc taacaattct tgaataactt ctctcatctt atttgtcctt tttatttttt
    38221 agataaatat atacattgat tgcaattata aaaatagcta ttgcactaac cattgcattt
    38281 cctctttcca tttgataaaa tagaggtgta aggggctttc gccccaacct cttagcgttt
    38341 acctttttct ttgacgggat ttcggtttac gctttttgtt ttgccttgcg accgttattg
    38401 cggtcactag acttgcgata gcagttaccg tttcaggaat attgtctatt gccttttcaa
    38461 gtaacctgag ccaatcttct ttgttcaact tcatcacccc ctttccttat cttgattata
    38521 ttatatcacg gtacaccgag aaagtcaagc gttttgatga agtttttttt aattttttca
    38581 aaaaaaaata gaccttgtcc agaggtcggg gagttggagg gggcaccctc caaaagcatt
    38641 gatttaataa ggttttattt tacctttttc ataataatct ccctatagag tcaccgcatt
    38701 cggtggcttt ttttgtgttg ggattcatga tataataata aaatcgataa gtaggaaaag
    38761 agaaaagaga tgtattatac gcttgaagaa aaagaagtct ttatgaggga ggctttgaga
    38821 gaggctgaga ttgctcttga acacgatgaa attccaattg gttgtgtgat tgtcaaagat
    38881 ggggaaatca ttggtcgtgg gcataatgcg cgtgaggaat tacagcgagc ggttatgcat
    38941 gcggaaatta tggctataga ggatgcgaac ttgagtgagg agagctggcg cttgctggat
    39001 tgcacacttt ttgtgaccat tgaaccttgt gtcatgtgta gtggagcgat tgggcttgcc
    39061 cgcattccaa atgtggtcta tggggctaaa aaccagaaat ttggcgctgc tgggagtttg
    39121 tacaatatct tgacagatga gcgtctcaat catcgtgtgg aggttgaaat aggaattttg
    39181 gaagatgaat gcgcagctat catgcaggat ttttttagaa atagacggaa aaaataattt
    39241 tgcttttaaa atgaatagga atgtgatata ataaatagtg gagcaacagt tctgcgtgaa
    39301 gcgggtcagg ggaggaatcc agcagcccta agcgatttga attgtgtgct ctttttttcg
    39361 tgctttttcc gaataaataa gatagaataa tctagaataa atgataatag aaaagagaaa
    39421 attatgaaaa ttcgtggttt tgaattggtt tcgagtttta cagatgaaaa tttattgccc
    39481 aagcgtgaga cagcgcatgc ggctggttac gacttaaagg ttgctgtgcg tacagttgtt
    39541 gcgccaggag agattgtctt ggttccgaca ggggttaagg cttatatgca gccgactgag
    39601 gttctctacc tctatgatcg ttcttcaaat cctcgtaaga agggcttggt tttaattaac
    39661 tcagttgggg tcattgatgg ggattattat ggaaatcctg gaaatgaagg gcatattttt
    39721 gcgcagatga agaatatcac agatcaagag gttgttcttg aagttgggga acgtattgtc
    39781 caggctgttt ttgctacttt cttaattgca gatggagatg cagctgatgg cgttcgaact
    39841 ggtggatttg gatcgacagg gcactagaat gaagattatc tttgtacgtc atggggagcc
    39901 agattaccgt gagttagagg agcgttctta tataggattt gggatagatt tggcaccctt
    39961 gtctgagatg ggacggcagc aagtccagaa attgagcaaa aatcctttac tctcgtcagc
    40021 tgaaataatc gtatcttctg cagtcacaag agctttagaa acggcttcgt atgtggtctg
    40081 tgctacgggt cttcctttaa gagtagagcc tttattacat gaatggcagg tctataaaac
    40141 aggaatagaa aactttgaaa cagctagaag actgttttta gaaaacaagg gggagttgct
    40201 tcctaatagt cctattcaat atgagacagc tacggaaatg aagtctcggt ttctagaatg
    40261 tatgtctaag tatcgagaac atcagactgt ggtagttgtt gctcatcgaa tgctcatgcg
    40321 ccagtttgtg ccaaatgaga agattgattt ttgccaagtg attgagtgtg agttagagat
    40381 atagaaagag gtttgtcatc gcaaagaaaa aagcgacatt tgtatgtcaa aattgtgggt
    40441 ataattcccc taaatatctg ggacgttgcc ccaactgtgg gtcttggtct tcttttgtgg
    40501 aagaggttga ggttgccgag gtcaagaatg cgcgtgtgtc cttgacaggt gagaaaacca
    40561 agcccatgaa actagctgag gtgacttcca tcaatgtcaa tcgaaccaag acggagatgg
    40621 aggaattcaa ccgtgtgctt ggaggcggag tggtaccagg aagtctcgtc ctcatcggtg
    40681 gggatcctgg gattgggaaa tcaactcttc tcctacaagt ctcaacccag ttgtcccaag
    40741 tggggacagt tctctatgtc agtggggagg agtctgccca gcagattaaa ttacgtgcag
    40801 agcgcttagg tgatattgat agtgagtttt atctctatgc agagaccaat atgcagagtg
    40861 ttcgtgcaga agtggagcgt atccagccag acttcttcat tattgactct atccagacca
    40921 ttatgtctcc tgagatttca ggggtgcagg ggtctgtttc tcaggtgcgt gaagtgaccg
    40981 ctgaactcat gcagttggcc aagaccaata acattgccat ctttatcgta ggtcatgtga
    41041 ccaaagaagg aaccttggct gggcctcgta tgttggagca tatggtggat acggtgcttt
    41101 actttgaagg ggagcgtcac cacacctttc gtattttgag agcggtcaaa aatcgttttg
    41161 gttccactaa tgagattggg atttttgaga tgcagtcggg cggcttggtt gaggtactca
    41221 atccgagtca agttttccta gaagagcgtt tggatggggc gactggttcc tccatcgttg
    41281 taaccatgga agggacgcgt ccgattttgg cggaggttca ggctttagta acaccgacca
    41341 tgtttggaaa tgccaagcgt actacgacag gacttgattt taaccgtgct agcttgatta
    41401 tggctgtttt ggaaaaacgg gcagggcttc tcttgcaaaa tcaggatgcc tatctcaaat
    41461 ctgctggtgg tgttaaattg gatgaacctg ccattgactt ggctgttgca gttgctattg
    41521 cttcgagcta caaagacaaa ccaactaatc ctcaggaatg ttttgtcgga gaactgggct
    41581 tgacaggaga gattcggcgc gtgaatcgta ttgagcaacg catcaacgaa gctgctaaac
    41641 tgggctttac taagatttat gtacctaaga attccttgac aggaatcact ctgcctaagg
    41701 aaattcaggt cattggcgtg acaacgattc aggaagtttt gaaaaaggtc tttgcataat
    41761 ccgtgacaaa ttctcttaaa aatgataaga taggagaaat atttgactat caaattttca
    41821 aggagggaat cgtgtcgtat tttgaacagt ttatgcaagc caatcaggct tatgttgccc
    41881 tacatgggca gttaaatctg ccacttaaac ccaaaacaag agtagctatt gtgacctgta
    41941 tggactctcg tctgcacgtt gcgcaagctc tgggcttggc acttggggat gctcatatct
    42001 tgcggaatgc aggtggtcga gtgactgaag acatgattcg ttcgctagtt atttcccagc
    42061 aacaaatggg gacaagagag attgtggtat tgcaccatac agactgtggt gctcagacct
    42121 ttgaaaatga accttttcag gagtatttaa aagaggaatt aggtgtagat gtgtcagacc
    42181 aggatttctt gcccttccaa gatatagaag agagtgtacg cgaggatatg caactgctta
    42241 tcgagtctcc cctaatacca gacgatgtca ttatctctgg tgccatttac aatgttgata
    42301 caggaagtat gacagtcgta gaattataaa tacttcattt agaaagaaag tgtatgaaga
    42361 aaagcagtat tttattgcta tgtattggtt tacagtatga aaccatctac tatacggacg
    42421 gttcgaggtc aggtgcggaa tatggactaa tgggaatttc tatctttcta gctctctttt
    42481 acatgattcc ggctctttat tttctcttcc gtattgggaa aaatgggaat tgccaaagaa
    42541 ggttttgatt ctgtctttat tgggagggat gttcctttca ggctggttgt ctagttttgc
    42601 taatacttat atccatgatt tactgggggt tcttttccca gatagtacat ttttaaatgc
    42661 ctttgaaagt gctattgtgg ctcctttggt agaagaaccc ttgaaattat tgccacttgt
    42721 ttttgttttg gctttgattc ctgtgcgaaa attaaaatct ttgtttttac ttggaattgc
    42781 ttccggtttg ggattccaaa tgattgagga tattggttat attcgtacgg atttgccaga
    42841 gggctttgac tttactattt cgcgaatttt agagcgtatc atctcaggaa ttgcctctca
    42901 ctggactttt tcaggtctag ctgtagtagg tgtttacttg ctttacagag cctataaagg
    42961 acagaaggtt ggcaagaaac agggccttat ttttctaggt ttagccttgg gaactcactt
    43021 cttgtttaac tctccttttg tggagttgga aacagagttg cctttagcga ttccagtggt
    43081 tacggctatt gctctctatg gtttttatca tgcttattgc tttgttgaga aacacaatga
    43141 gttgatgacc tagaatattt ttcaaaagaa tgatgcaagg gtacaaatat ggtgcccttc
    43201 ttttattttt gattgaaaaa tagtgcaaaa agcgctacaa tggtagatgg aaaatcttgt
    43261 gaaaggcaca agttatacat atataccgga ggaaatcatg tctttttctg atttaaagct
    43321 gtttgccctt tcttctaata aagaattggc agaacgtgtg gcgcaggaga ttgggataga
    43381 gttggggaaa tcaagtgttc gccaattttc agatggagag attcaggtca acattgaaga
    43441 atcaatccgt gggaaacacg tctttatctt acaatcaact agttcgcctg taaatgacaa
    43501 tctgcttgaa attttgatta tggtagatgc tttgaagcgt gcgagtgcag aatctgtcaa
    43561 tgttgtcatg ccttactatg ggtatgcacg tcaggataga aaggcgagag cgcgtgagcc
    43621 aatcacttca aaacttgtcg caaatatgct tgaagtagct ggagtggatc gtttattgac
    43681 catcgacttg catgctgcgc aaattcaagg attctttgat attcctgtgg atcatttgat
    43741 gggtgctcct ctgattgcag attattttga gcgtcgtggt atggttggtt ctgactatgt
    43801 ggttgtcagc ccggaccatg gaggggtgac tcgtgctcgt aagttggcag aatttttgaa
    43861 aacatctatc gctattattg ataaacgtcg tagcgttgat aagatgaata ctagtgaagt
    43921 tatgaatatc atcggtaagg ttgaaggcaa gacttgtatc ttgattgatg atatgattga
    43981 taccgctgga acgatttgtc atgcggcaga tgctcttgcg gaagctggtg ctgttgaagt
    44041 ctatgcaagc tgtacgcacc cagttctttc tggtcctgct acggacaata tccaaaaatc
    44101 agctattaag aaattggttg ttttggatac catctatctg ccagaagagc gtttgattga
    44161 taagattgag cagatttcaa tcgctcatct cctaggggat gctatcgtac gtattcatga
    44221 aaaacgacca ctttctccac ttttcgatat tgagaaaaaa atttaatgac caagcctgag
    44281 atgattctca ggttttttcg tcttttttcc gaataaatag atagtagcgg tgaatctagt
    44341 aaagctagat ttaaaactgt gatataataa aaagagaaga aatatgactg tacgtcat
//
LOCUS       DAVBNZ010000010        43719 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000010 DAVBNZ010000000
VERSION     DAVBNZ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43719
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.010"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            131..412
                     /locus_tag="VQ860_000587"
                     /pseudo
     CDS             131..412
                     /locus_tag="VQ860_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(537..740)
                     /locus_tag="VQ860_000588"
     CDS             complement(537..740)
                     /locus_tag="VQ860_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3119069.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(733..1815)
                     /locus_tag="VQ860_000589"
     CDS             complement(733..1815)
                     /locus_tag="VQ860_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3119070.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1941..2723)
                     /locus_tag="VQ860_000590"
     CDS             complement(1941..2723)
                     /locus_tag="VQ860_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET3119071.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2723..4066)
                     /locus_tag="VQ860_000591"
     CDS             complement(2723..4066)
                     /locus_tag="VQ860_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET3119072.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKKCTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4165..5481)
                     /locus_tag="VQ860_000592"
     CDS             complement(4165..5481)
                     /locus_tag="VQ860_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET3119073.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5675..6901
                     /locus_tag="VQ860_000593"
     CDS             5675..6901
                     /locus_tag="VQ860_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET3119074.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7100..8674
                     /locus_tag="VQ860_000594"
     CDS             7100..8674
                     /locus_tag="VQ860_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3119075.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8939..9727
                     /gene="codY"
                     /locus_tag="VQ860_000595"
     CDS             8939..9727
                     /gene="codY"
                     /locus_tag="VQ860_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET3119076.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9727..10302
                     /locus_tag="VQ860_000596"
     CDS             9727..10302
                     /locus_tag="VQ860_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3119077.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGNFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10384..10469
                     /locus_tag="VQ860_000597"
     tRNA            10384..10469
                     /locus_tag="VQ860_000597"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10418..10420,aa:Leu,seq:aag)
     gene            10752..11882
                     /gene="ugpC"
                     /locus_tag="VQ860_000598"
     CDS             10752..11882
                     /gene="ugpC"
                     /locus_tag="VQ860_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET3119078.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12383..13141
                     /locus_tag="VQ860_000599"
     CDS             12383..13141
                     /locus_tag="VQ860_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3119079.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13228..13740
                     /locus_tag="VQ860_000600"
     CDS             13228..13740
                     /locus_tag="VQ860_000600"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET3119080.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13922..14866
                     /locus_tag="VQ860_000601"
     CDS             13922..14866
                     /locus_tag="VQ860_000601"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET3119081.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14875..15552
                     /locus_tag="VQ860_000602"
     CDS             14875..15552
                     /locus_tag="VQ860_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET3119082.1"
                     /translation="MTYLDAFKSGILVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            15650..16408
                     /locus_tag="VQ860_000603"
     CDS             15650..16408
                     /locus_tag="VQ860_000603"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET3119083.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16446..17951
                     /gene="lytC"
                     /locus_tag="VQ860_000604"
     CDS             16446..17951
                     /gene="lytC"
                     /locus_tag="VQ860_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET3119084.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18448..18966
                     /locus_tag="VQ860_000605"
     CDS             18448..18966
                     /locus_tag="VQ860_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET3119085.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEASEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19096..19602
                     /locus_tag="VQ860_000606"
     CDS             19096..19602
                     /locus_tag="VQ860_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET3119086.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEL"
     gene            19804..21036
                     /gene="clpX"
                     /locus_tag="VQ860_000607"
     CDS             19804..21036
                     /gene="clpX"
                     /locus_tag="VQ860_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET3119087.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21045..21632
                     /locus_tag="VQ860_000608"
     CDS             21045..21632
                     /locus_tag="VQ860_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET3119088.1"
                     /translation="MELNIHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21643..22023
                     /locus_tag="VQ860_000609"
     CDS             21643..22023
                     /locus_tag="VQ860_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET3119089.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22075..22965
                     /gene="rapZ"
                     /locus_tag="VQ860_000610"
     CDS             22075..22965
                     /gene="rapZ"
                     /locus_tag="VQ860_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET3119090.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22962..23939
                     /locus_tag="VQ860_000611"
     CDS             22962..23939
                     /locus_tag="VQ860_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET3119091.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQKYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23936..24847
                     /gene="whiA"
                     /locus_tag="VQ860_000612"
     CDS             23936..24847
                     /gene="whiA"
                     /locus_tag="VQ860_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET3119092.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24881..25849)
                     /locus_tag="VQ860_000613"
     CDS             complement(24881..25849)
                     /locus_tag="VQ860_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3119093.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25985..26842
                     /locus_tag="VQ860_000614"
     CDS             25985..26842
                     /locus_tag="VQ860_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET3119094.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26829..27608
                     /locus_tag="VQ860_000615"
     CDS             26829..27608
                     /locus_tag="VQ860_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET3119095.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27632..28984
                     /locus_tag="VQ860_000616"
     CDS             27632..28984
                     /locus_tag="VQ860_000616"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET3119096.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            29058..29432
                     /locus_tag="VQ860_000617"
     CDS             29058..29432
                     /locus_tag="VQ860_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET3119097.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29434..30282
                     /locus_tag="VQ860_000618"
     CDS             29434..30282
                     /locus_tag="VQ860_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3119098.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30559..31326
                     /locus_tag="VQ860_000619"
     CDS             30559..31326
                     /locus_tag="VQ860_000619"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET3119099.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLACFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRTQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEIRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31338..32522
                     /locus_tag="VQ860_000620"
     CDS             31338..32522
                     /locus_tag="VQ860_000620"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET3119100.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32519..34390
                     /locus_tag="VQ860_000621"
     CDS             32519..34390
                     /locus_tag="VQ860_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3119101.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTILSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELVWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34533..35717)
                     /gene="mntE"
                     /locus_tag="VQ860_000622"
     CDS             complement(34533..35717)
                     /gene="mntE"
                     /locus_tag="VQ860_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET3119102.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            36021..38717
                     /locus_tag="VQ860_000623"
     CDS             36021..38717
                     /locus_tag="VQ860_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET3119103.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLVEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILAIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38730..39521
                     /gene="yghU"
                     /locus_tag="VQ860_000624"
     CDS             38730..39521
                     /gene="yghU"
                     /locus_tag="VQ860_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET3119104.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39637..40047
                     /locus_tag="VQ860_000625"
     CDS             39637..40047
                     /locus_tag="VQ860_000625"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3119105.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            40059..41654
                     /locus_tag="VQ860_000626"
     CDS             40059..41654
                     /locus_tag="VQ860_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119106.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            41721..41885
                     /locus_tag="VQ860_000627"
     CDS             41721..41885
                     /locus_tag="VQ860_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET3119107.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            41964..42692
                     /gene="yaaA"
                     /locus_tag="VQ860_000628"
     CDS             41964..42692
                     /gene="yaaA"
                     /locus_tag="VQ860_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET3119108.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPVLSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDETLKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTLKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42969..43517)
                     /locus_tag="VQ860_000629"
     CDS             complement(42969..43517)
                     /locus_tag="VQ860_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3119109.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
BASE COUNT        12874 a         8170 c         9946 g        12729 t
ORIGIN      
        1 aagaaagaca gaaattgttc aagaattaat gactgagttt tcgttagttc ttcttctaaa
       61 agccattaaa ctagctcgtt cgacctacta ctatcacttg aaacagctag acaaaacaga
      121 taaggactaa ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg
      181 aattcaagca tctatgtcac gcaagggaaa cagccaagac aacggtatga tggagtcctt
      241 ctttggcatt ttaaaatccg aaatgtttta tggctatgag aaaacattta aatcacttaa
      301 tcaattggaa caagccatta tagactatat tgattattac aacaataaga aaattaagtt
      361 aaaactaaaa ggacttagcc ctgtgcaata cagaactaaa tccttcggat aaattaattg
      421 tctaactttt tgggggcagt acacaatacc tgatagtatg cgttttattg tgggaagatt
      481 ttcctcattt tctagtgaaa ttgaactttt tctaacatct tttgatagat gacttcttaa
      541 tcaattatca tttccattgt tgtttcttgg ggtttcatcc cttgtctttg ataaaagcgg
      601 agagcaccct cgttatcatt ccagacactt agggttagat tattgcagcc aatttcttta
      661 gcataatagc agaaaaatga caataaaata gcccctagat attttgaaag gaaagcatag
      721 gggctatata gtttaatcaa aataaagcaa atctttgctg gtgcttgtaa agaggtcgaa
      781 gccatccttg gtaacaacac cgcagtcttc aatacgaaca ccgactttac cagggatata
      841 gatacctggt tcaacagaga agcacatgcc ttcttcgatg accatgtcgt ttccttccat
      901 gatagatggg aattcatgga catccatacc gataccatgc ccgagacggt gattgaagta
      961 ctcaccataa ccagcttttt cgatgacctc acgggcagcg cggtccactt catgagcagt
     1021 cacacctggc ttgataaagt caagagcagc ttgttgggct tcaagagtca agttgtaaat
     1081 atctttcttg aattggtctg gtttgccgac agcgactgta cgagtcatat ctgacgcata
     1141 gccattgacc agaacaccca ggtcaaagag gagaagagca tcattttcaa ccttattagc
     1201 tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc aagaccatgg tatcaaagct
     1261 catttcataa ccttcacgtt tcatggcaaa gtcgatttgt gcgatgatat ctgtctcagt
     1321 cttatcaaga gaaatattgt caaaaccaac atgaacagcc ttgtcagcat aaagacctgc
     1381 aaccatcatt ttttgcactt catcagctga tttgatgagg cgcatgcgtt ggatacgagg
     1441 agtgaggttg tcaaactcag cagtctcaaa aactgttttc aaaccatggt atttggtcaa
     1501 gatgagattg tcaaactcaa cagcgacacg tttgaagtca agttgtggaa gagcatgttt
     1561 gattttttgc catggatttt cagaatcgac atagcccact actgggaagg aaacggtgct
     1621 acttgcacgt tctacttcaa gagctgggac aaagaggaga ggttcctgat ccgctaggac
     1681 aaagaggaac atttggcgtt catggggatc actgtaaaaa ccagtgaggt aattgattgt
     1741 gacggggtca gatacgacag cgacgtctag tttttctgat tcaagatatg ttaggatttg
     1801 ttgtaattta gacatatgct accttctttc tacccctcta ttttggcaaa aaatgagaga
     1861 aaatgcaagg gagaagggta aaagaaaaga caaaaaactc cgacaagata acggagttct
     1921 ttgatatcat tttcctttgt ttaagaaaag tcagccttgc ttttgacgtc actgtactct
     1981 tcagcgattt cttggctgag gatatcctca taggcaggga gttggatatc ctgaccatat
     2041 ttcttcttga gggcagtagt aactaggcga taagccagat tggcattacg agagaggata
     2101 ggcccgtgga agtaggaacc aaagacattc ttataatgaa ccccttcacc gaccttttct
     2161 tcgttgtttc catttccata gacaacctgt cccagcggtt tttggtcatc agagaggaag
     2221 gtacggcctt ggtgattttc aaatccatag taggtttcat cgaaatcttc attgtgaatc
     2281 ttgatgtcac cgataaaacg gttattggtc tggttgagcg tgtagtgtcc catgacccct
     2341 agcccttcga tacgttttcc tgaagcttca acataatatt gacccaatag ttggaaacca
     2401 ccgcagatag ccagaactac accgtcgttt tggatgtagt tgtcaatgct ctctttttta
     2461 gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt gaccaccacc gaaaaaggcg
     2521 atgtcgtagt gattttcatc aaagtcatca tggagagaaa cgatgtcaac ggtcacatgg
     2581 gctcccagtt tttcagccac atatttgagc atgaggatgt ttccattgtc cccgtaggta
     2641 ttcatgagat ttccgtagag gtgggcaatg ttgagctgat aggggtaatt gccatctttt
     2701 gaggaaagtg aagtataaac cattagttca tctcctttct aacaatctga cgactagcca
     2761 gcagttcacg aaattccagc atggcagtat aagttgccag aatataggca tgcttgcagt
     2821 cttgattctc aatggtcttg agaacttgct ccagattact cgtttcagtg attttctcag
     2881 ctggatagcc agtcactcgg aggcgacgag cgatttcaga atgacgaaca ccgccagcgt
     2941 tgatttcagg aatgtccatg tcagtgattt gctcaaagtc tgcatcccag atccagctag
     3001 tgtcaattcc atctgcatag ttggcattaa ggaggacaga taggctaaat ggataaggtg
     3061 ctagtttgat catttcgata gcttgggttg caccgactgg atttttaatc aagacaaggg
     3121 tacatttctt gtcaccgata tgaaaggttt cttggcgtcc aaagacagca cggctcttgt
     3181 caaatccctg tttgatgagt tgcgaatcgg cacctaggaa acgggcgatg gccacagcag
     3241 ctagggcgtt atagatatta tagagcccgc cgatttggat accgtattct tggccgtcta
     3301 tgacaaagcg agagcgattg ttggtcaact caaccagttt tgtcaaacga tagtcgagat
     3361 caggacgttt acatccacaa ccttcacaga tataggcacc caagtttgca taggtattat
     3421 gctcatattt gaggatgcct tggcagtcag gacagagaat cccttcggta ttgtagtgag
     3481 ccagttgggc tggtcctttt tccaagtcaa aaccaaaata ctctataggg tttggaatag
     3541 ttggcttgta gaaaagtgga ctgtctccgt taaggagaac agtagcagtt ggaacttttc
     3601 gaatggcatc caatatcatg ttataggtag tatagatttc accgaaacgg tccatctggt
     3661 cacggaagat attagtaatg acaaaaagac taggctggat atagtcacag atacgagata
     3721 gactggcttc gtcaatttcg aggacggcaa tatttttccc agtttttgaa gatttggctg
     3781 ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc gcttgggttg gttagaactt
     3841 gaccataaac ctcttttaaa atgccgacag tgagggcagt tgtcagggtt tttccatttg
     3901 ttccagtgac aacgacaatc tcgtagttct tagctaggtt ttgtaaaata tctttatcaa
     3961 attgaagggc gactttacct gggagcgtac ttccacgtcc aagacggctt aaaacgaagt
     4021 gggaagaacg cccagcaaga aggcccaaag tagtttttaa gttcatgttt ctattatatc
     4081 acaaaagagg gaaaagacag atttggtgtt tcgtagaagt aaaaacagcc caaagagggc
     4141 tgtcagttaa gatgagattt caacttaaat cgcaaacaag tcattcaagt tctcagccaa
     4201 ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa ggaatcttgt tgtccatagc
     4261 aacagtaatg atgttgatga tttcttgaga accttctgag aagatgcttg caccaagaat
     4321 ttcttttgtt tcagtattaa caacagcttt gaaagctccg cgaaggtctc catttacgtg
     4381 accacgaggc atggctgcaa cagggatttc tttcactgcg tatggaagtt tcaaatcagc
     4441 tgcttggctt tcagtcaaac caacttgtga aagtgcaggt gtgatgaaca tagtatttgg
     4501 cacattgaga cggtcctcaa gtgtgtagct gccatctcca gcaaggtagc tgtaaacaac
     4561 acggaagtca tcaagtgaaa tgtaagtaaa ttgaagacca ccgttgacat ctccaactgc
     4621 aaagacacca ggaacgtttg tttgacagtg tttatctact ttaatagcgc cacgttcagt
     4681 tagttcaata tctgtatttt caagttgaag tggttctaca tttggtttgc gtccagttgc
     4741 gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt acgacaagca cttggtcacc
     4801 gtcgttttta atttcagtag tatggatatt ttgaagcaat tcaataccgt cttcttccag
     4861 gtattgttta gcaagagctg cgatggaagg ttctgcacga ggtaggaatg tatccaaggc
     4921 atctaggact gtaaccttgc ttcctagttt attgtaaagg ccagcaaatt caagaccgat
     4981 atttccgcca ccaaggactc caagtttttc aggcaattta tccaagcttt ggatacctgt
     5041 tgagtcaaag acgtttttgc ttgtagcaag tccagggatt ggcaagacgt ttgaaacagc
     5101 accagtgttg atgacgatag tttcagcagt caattcttgt ttttcatcac cagcttggat
     5161 ttcgatgact ttatttgaaa ggaagtgagc ttcagcatca aagatattga cgccagtacc
     5221 agcaacagtc gtatagtttt taccgttgag gcgaccagtg atcgtgtttt tggtagcaat
     5281 gacttcttca aaagacaagt ctttctcagc agcaaccagc aaagttttag ttgggataca
     5341 accgatgttg atacaagttc caccgtacat agctttgcta cgttcaacga gggcaacttt
     5401 tttgccagct gaagccaatt taccagctag tgttttacca gctttaccaa atccgataac
     5461 gattaaatca taagttaaca tttagaattc ctcctattcg aattacattc tagcacaaga
     5521 aaaaaacttt tgcacaattc tgctacgaaa aagacagaaa aagatgaaaa cgctttccag
     5581 acaaaaaact agtaattttt tgacaagctt gataaactaa aatcctatct atttttatat
     5641 aataaagaat aaatgttcga aaataggagg ttttatgaaa tcgaatcgtt atattattgc
     5701 ctttgctggg gtcattttac acttaatgct gggttcgact tatgcctgga gtgtttatcg
     5761 taaccctatt attgaaaaaa cgggatggga tcaggcttct gttgccttcg cctttagtct
     5821 agcaatcttt tgtttgggct tatcggctgc atttatgggg cgtttggtag aaaaatttgg
     5881 tccgaaagtc atgggaagtc tatctgcttt tctatacgca ggtggaaata tcttaacagg
     5941 atttgcaata gaccgtcagg agctgtggtt gttgtatctc gcttatggca ttttaggtgg
     6001 gcttggtttg ggagcaggct atattacccc tgtgtcgacg attataaaat ggtttcctga
     6061 taaacgtggt ctcgcaacag gtttagcgat tatggggttt ggttttgctt ctttattgac
     6121 tagtcccata gcgcaacacc tcatcgcagg ggtagggctt gtagaaactt tttatatttt
     6181 aggagcaagt tactttatta tcatgctcct agcttcacaa ttcattaagc gtccaaatga
     6241 gcaagagctt gcaattttat cttcttcagg gaaagaaaaa acagcctctt tgacgcaagg
     6301 aatggctgca aatcaggctc taaaaagcaa tcggttttat atgctttgga ttattttctt
     6361 tatcaacata gcttgtggtt taggcttaat ttcagcggca tcgccaatgg cacaggagat
     6421 ggctggcttg tctacaagtc atgcagcagt aatggtgggt gttttgggga ttttcaatgg
     6481 atttggtcgc ttgctctggg cgagtttgtc tgactatatc ggtcgccctc taacctttag
     6541 tatattactg cttgttaatc ttttcttttc tctctcactt tggctcttta cagattccgt
     6601 tttatttgta gtcgctatgt ctattttgat gacttgctat ggagctggtt tttcattgat
     6661 cccagcttat ctcagtgata tttttggaac caaggaattg gccgctctgc atggatatat
     6721 tttaacagct tgggcaatgg ctggtttagc gggacctatt ttattagcag agacttataa
     6781 aatggctcat tcgtacacac aaaccttgtt cgtttttctc attttataca gtatcgcctt
     6841 ggctttgtct tattatctag gtcgttcaat caaaaaagaa agtcaaaaac cgcttacatg
     6901 attttctgta gaaatgggac tatcttttgc tctggtcttg tgttatacta gataggttgc
     6961 aaagaaaaca gtacttttct tttgtggaaa agaagcaaca cgattttata tctagttata
     7021 tgaaaatacg tcataaaaag aaaagtataa actaagccct atagggtggc ttcgcaccac
     7081 ctttagaaag aagaataacg tgaaatttaa tgaattaaac ttgtctgctg atttgctggc
     7141 agaaattgaa aaagctggtt ttgtagaagc tagtcctatc caagaacaaa ctattccttt
     7201 ggcccttgaa ggcaaggatg ttatcggtca agctcagact ggtacaggaa aaactgcagc
     7261 ctttggcttg cctacccttg aaaaaatccg tacagaagaa gcgactatcc aagccttagt
     7321 catcgctcca actcgtgaac tagctgtcca aagtcaagaa gaactcttcc gctttggtcg
     7381 tagtaaggga gtcaaagtcc gttcagtata tggcggatca agcattgaaa aacaaattaa
     7441 ggctcttaaa tctggtgccc atatcgtggt gggaactcca ggtcgcctct tggacttgat
     7501 taaacgcaag gccttgaaat tacaaaacat tgaaaccctt atccttgacg aagcggatga
     7561 aatgcttaac atgggcttcc ttgaagacat cgaagccatt atttcccgtg tacctgagaa
     7621 ccgtcaaact ttgcttttct cagcaactat gccagatgcc atcaaacgta tcggtgttca
     7681 gtttatgaaa gcccctgaac atgtcaagat tgcggctaag gaattgacaa cagaattggt
     7741 tgaccagtac tatatccgtg ttaaggaaca agaaaaattt gacaccatga ctcgtctcat
     7801 ggatgtggca caaccagaac tcgctattgt atttggtcgt accaaacgcc gtgtggatga
     7861 attgactcgt ggtttgaaaa ttcgtggctt ccgtgcagaa ggaattcatg gcgacctaga
     7921 ccaaaacaaa cgtcttcgtg tccttcgtga ctttaaaaat ggcaatcttg atgttttggt
     7981 tgcgacagac gttgcagcgc gtggtttgga tatttcaggt gtgacccatg tctacaacta
     8041 cgatattcca caagatcctg agagttatgt tcaccgtatc ggtcgtacag gtcgtgctgg
     8101 taagtcaggt caatctatta cttttgttgc tccaaacgaa atgggttacc ttcaaatcat
     8161 tgaaaacttg actaagaaac gcatgaaagg tctcaaacct gcaagtgtag aagaatcctt
     8221 ccaatcaaaa aaacaggtag ctctcaagaa aatcgaacgt gattttgcag atgaaaccat
     8281 tcgtgccaat tttgagaaat ttggtaagga tgctcgcaaa ttggctgctg agtttactcc
     8341 agaagaattg gcaatgtata tcttgagtct gacagtccaa gacccagata gccttccaga
     8401 agtggagatt gcacgtgaaa aaccactacc gtttaaacca tcaggtaatg gtttcggtgg
     8461 taaagctaag ggaggtcgtg gaggccgtcg tggggacgac cgtcgagagc gtgatcgccg
     8521 tggcaatggt cgccgtgatg agttcaaaaa aggaagtcgt ggcaacgatc gttttgataa
     8581 ggaaaaacgt taccgtaagg ataataaaaa accacgcaat actttaagcg aaaagcaaac
     8641 aggctttgtt attcgtaaca aaggtgataa ataagaaaaa gcggttcaaa atgaatcgct
     8701 tttttatata aggagaccga atgtgaaaaa gacaaataaa attattatat tatcttttat
     8761 aatattatga tacacaaaaa taggcaactt gtcaatagaa aaggaacaat ttaattaaaa
     8821 atattctggt ttttaattaa attgtaagtc aatgcaagtc aataaggaat tttcagataa
     8881 ttattgaaaa agagacgttt ttatgttata atgatagcga ttaaattcga ggtgaaaaat
     8941 ggcacattta ttagaaaaaa ctagaaaaat tacatcaatt ttgaaacgct cagaggagca
     9001 gttgcaggat gagcttcctt acaacgctat tacgcgtcag ttagcggata ttattcattg
     9061 caatgcctgc attatcaata gtaagggacg tctgcttggc tattttatgc gttataaaac
     9121 aaatacagat cgcgtagagc aattcttcca aactaagatt ttcccagatg actacgttca
     9181 aggggctaat atgatttacg aaacagaagc aaacttacct gttgagcatg atatgagtat
     9241 tttccctgtt gagagtagag atgattttcc agatggcttg acgactattg caccgattca
     9301 tgtatcgggg attcgccttg gttctttgat tatttggcgt aatgataaaa aattcgaaga
     9361 tgaggacttg gttcttgttg agattgccag taccgttgtt gggattcagc ttcttaactt
     9421 ccaacgtgaa gaagatgaga aaaatattcg tcgtcgtact gctgtcacca tggcggtcaa
     9481 taccctttct tactccgaac tccgtgctgt ttcagcaatt ttaggggaat taaatggaaa
     9541 tgaagggaag ttgactgcgt cagtgattgc agatcgtatc ggaatcactc gctctgtgat
     9601 tgtcaatgct cttcgtaaac ttgagtctgc ggggattatt gaaagtcgct cacttggaat
     9661 gaagggaacc tatcttaagg tcttgatttc agatattttt gaagaagtga agaaaagaga
     9721 ttactaatga caaaggcttt aatttcgatt gattatacag aagattttgt tgctgatagt
     9781 gggaaactaa cagcaggtgc tccagctcag gcgatttcgg atgccatcag caaggtaact
     9841 cgattagctt ttgaacgagg agattatatc ttctttacta ttgatgctca tgaagaaaac
     9901 gattgtttcc atccggaaag taagttattt cctcctcata atctgattgg gacgagtgga
     9961 cggaatttat atggagattt ggggaacttt tatcaagagc atggttcaga cagtcgtgtc
    10021 ttttggatgg ataaacgcca ttactcagct ttttcaggga ctgacctaga tattcgtttg
    10081 agagagcgta gagtgtctac cgttatctta acaggtgtct tgacggatat ctgtgtccta
    10141 catacagcta tagatgccta taatctagga tatgacatcg agattgttaa accagctgtt
    10201 gcttccatct ggcctgaaaa tcatcaattt gccctaggtc atttcaaaaa tacactcgga
    10261 gctaagttag tagatgaaaa tctaaatgaa ctttctgagt aacctggttg gtgaaaatga
    10321 aaaaatttga aaaaaagtgt tgacaagcat cccaaaagtt gatatactag taaagtaatc
    10381 gatgcgggga tggcggaatt ggcagacgcg caggactaag gatcctgtga ccgctttagg
    10441 tcgtgagggt tcaagtccct ctctccgcat aggaaaagag ttagctaaag ctagctcttt
    10501 tgtatttctc taaaaaatta gaatccagtc aaatgtagtg gagaatcagc gaaaatatgg
    10561 gaaaactgat ccttgtttct gcttttgtca tagaagaata ataaagatta tcttcttcaa
    10621 attctccgat attctctaaa gttttgtgca agttgcacag aactttttta tttttttggt
    10681 catcttgcca tagaaatata aagcgttttc atatataata taattatcaa aagacaaaag
    10741 gagttcacct catggtagaa ttgaatctta aaaatattta caaaaaatat ccaaacagcg
    10801 aacactattc agttgaagat ttcaacttga acatcaaaga taaagaattt atcgttttcg
    10861 taggaccttc aggatgtggt aaatcaacta cactccgtat gattgctggt cttgaagaca
    10921 ttacagaagg tactgcatct atcgatggcg tggttgtcaa cgacgtagct ccaaaagacc
    10981 gtgatatcgc catggtattc caaaactacg ctctttaccc acacatgact gtttatgaca
    11041 acatggcttt cggtttgaaa ttgcgtaaat acagcaaaga agacattaac aaacgtgttc
    11101 aagaagcagc tgaaatactt ggattgaaag aattcttgga acgtaaacca gctgaccttt
    11161 caggtggtca acgtcaacgt gttgccatgg ggcgtgcgat tgtccgtgat gcgaaagtat
    11221 tcttgatgga cgaacctttg tcaaacttgg atgccaaact tcgtgtatca atgcgtgctg
    11281 aaatcgctaa aattcaccgt cgtatcggag ctacaactat ctatgtaact cacgaccaaa
    11341 cagaagcgat gacacttgca gaccgtatcg ttattatgtc agctactaag aaccctgctg
    11401 gtacaggtac tatcggacgt gtagaacaaa tcggcactcc tcaagaagtt tacaaaaatc
    11461 cagttaacaa attcgttgca ggattcatcg gaagcccagc tatgaacttc atcaacgtga
    11521 aattggttgg tagcgaaatt gtttctgacg gtttccgttt gaaagtgcca gaaggagcat
    11581 tgaaagttct tcgtgaaaaa ggctacgaag gaaaagaatt gatctttggt atccgtccag
    11641 aagacgtgaa tgcagaacct gctttccttg aaacattccc agactgtgtt gtaaaagcga
    11701 ctatctctgt atcagaactg cttggttcag aatctcacct ttactgccaa gttggtaaag
    11761 acgagtttgt tgcaaaagtt gatgctcgtg actacttgca aacaggtgca acagttgagc
    11821 ttggatttga cttgaacaaa gcacacttct tcgatgtaga aactgaaaaa acaatctact
    11881 aaaataaata aaattcaaag cactacaaga aaagatattt ctttatcaat tgtagtggag
    11941 agatatcagt taatctaggg agagaaacaa aatgcttctc tcctttttgc tagggaagtc
    12001 atattatgca tctatattgt gatgctcttt aatactcttc gaaaatctct tcaaaccacg
    12061 tcaacgtcgc cttgccgtac gtatgattac tgacttcgtc agttttatct gcaacctcaa
    12121 agctgtactt tgagcagttt acggctagtt tcctagtttg ctctttgatt tccattgagt
    12181 attatttgtg ggtaccatct acaagtgaag ctatatgcgt aaactacgtg agcaattgaa
    12241 ttcgaactag agaggtaata ataaatttat gctatagtta tggtgacttg tatgcttttg
    12301 attctagttt atcaaataat agattagaat tgtcagataa tatcattttg tgttataatg
    12361 aagaaaaaac agaggtgttc aaatgtcaga agcaggtcat aagtttttag caaaattggg
    12421 gaaaaaacgc ttacgtccag gtggaaagcg tgccacagat tggttaattg cagaaggagg
    12481 attttcaaaa gaaaagagaa tactagaggt tgcgtgtaat aggggaacta cagcaattga
    12541 gttggcacag cgttttggtt gcaagataac tgctgttgat atggatgctc aagctttaga
    12601 agtggctaaa aaatctgctg gaacggcagg tgttgctcat ttaatcagtt ttgaaagagc
    12661 aaatgcaatg aaacttcctt atcaagatgc tagttttgat attgttataa atgaagctat
    12721 gctgactatg caagccgatc aagctaagaa aaaatgtgta atggaatatc taagggtatt
    12781 aaaacctgga ggtcttctct tgacacatga tgtacttctt aaggaagcta aagagtctat
    12841 cagacaggaa ttatcacaag caattcatgt aaatgtaggt cctttaactc aagatggttg
    12901 ggaacaggtg atgatagaat caggttattg tgatgtgaaa gcattgactg gtgaaatgac
    12961 attaatgaaa ttatcgggta tgatttatga cgaaggtttg ctaggaactt tgaaaatttg
    13021 tgtaaatgct tgtaaaaagg agaatagaaa gcagttttta actatgtata aaatgtttgc
    13081 taagaataaa cagaaattgg gctttattgc gatggctagt tataaatcgt caaaacgtta
    13141 gataattatt gaagttaact tttccttttt tctttcttaa aaaatatgct ataatagaga
    13201 gtaaaaaact ttgaaagaaa gaaaaagatg aatttaaaag attacattgc aacaattgaa
    13261 aattatccaa aggaaggcat taccttccgt gatattagtc ctttgatggc tgatggaaat
    13321 gcttatagct acgctgttcg tgaaatcgtt cagtatgcta ctgacaagaa agtcgacatg
    13381 atcgtgggac ctgaagctcg tggatttatc gtgggttgtc cagttgcctt tgagttggga
    13441 attggttttg cgcctgttcg taagccaggt aaattgccac gcgaagttat ttctgctgac
    13501 tatgaaaaag agtacggtgt cgataccttg actatgcacg cggatgccat taagccaggt
    13561 caacgtgttc ttattgtaga tgaccttttg gcgacaggtg gaactgttaa ggcaactatc
    13621 gagatgattg aaaaacttgg tggtgttatg gcaggttgtg ccttccttgt tgaattggat
    13681 gaattgaacg gccgtgaaaa aattggtgac tacgactaca aagttcttat gcattattaa
    13741 tgaaaacagt ccctagggct gttttctcta cactaggata taaaaataga ctataactag
    13801 ttagagaaaa actataattg aaaactatat cttcttacag tataataaaa ggactaagtg
    13861 tttgagattt gtcttcaaac atatgcaatt attcctgaaa gagtacagtt aggagagggt
    13921 tatgccgatt cgaattgata aaaaattgcc agctgttgag attttacgga cagagaatat
    13981 ctttgtcatg gatgatcaac gtgctgccca ccaagatatc cgtcctttga agattttaat
    14041 tttaaatctc atgccacaga aaatggtcac agagacccag ttgttgcgcc acttggctaa
    14101 tacaccccta caactggata ttgattttct ctatatggag agccaccgtt ctaaaacaac
    14161 tcgttcagag cacatggaga ccttctataa aacttttcct gaagtcaagg atgagtattt
    14221 tgatgggatg atcatcacgg gtgctccagt tgagcattta ccatttgagg aagtggacta
    14281 ttgggaggaa tttagacaga tgcttgagtg gtctaagact catgtctatt cgacccttca
    14341 tatctgttgg ggggctcagg ctgggcttta tctgcgctat ggtgtagaaa aataccagat
    14401 ggacagtaag ctatcaggta tttatcctca ggacacccta aaagagggtc accttctatt
    14461 tagaggcttt gatgatagct atgtatcccc tcattcacgg cacacggaga tttctaagga
    14521 agaggtctta aacaagacca atctcgagat tttatcagaa ggacctcagg ttggggtttc
    14581 tattttggcc agtcgtgatt tacgagaaat ttatagtttt ggtcatttgg agtatgaccg
    14641 tgataccttg gcaaaagagt attttcgaga tcgtgatgca ggtttcgacc cacatattcc
    14701 agaaaattac tttaaagatg atgatgttaa tcaggtacct tgtctttgtt ggtcttcatc
    14761 tgcagccctc tttttcagta attgggtaaa ccatgcggtc tatcaggaga cgccttttga
    14821 ttggagaaag atagaagatg atgcatctgc atatgggtat ttataagagg aattatgaca
    14881 tatttagacg cttttaaatc aggtatcttg gttttaccga gtgccctgct cttgcatttt
    14941 aaggaactct ttccttctag cgacgatttt ctggtttggc aatttttcta tttgcaaaat
    15001 acgacaggct tagaagaaat gtcgccaagc cagattgctg aaaggattgg caaggaaatt
    15061 tcggatgtca accagtccat ttctaatctg acggaaaggg gactgctcca gtatcgtact
    15121 atcgaattaa atggcgaaat tgaattgctc tttgatgcta gtttggcctt ggaacgtttg
    15181 gatgacctgt ttggagcagt tcattcaagt tcagaccagc tgacacctca aaaccagctc
    15241 aaggatttgg tggaaacctt ccagcaggag ttgggacgat tgttgacgcc ttttgagatt
    15301 gaggatttga ccaagacact aaaggaagat ggaaccagtg ctgacttgat taaggaggct
    15361 cttcgtgaag ctgttttgaa tggaaaacca aactggaagt acattcaggc gattttgaga
    15421 aactggcgcc atgaaggaat caagagtgtg gctcaaattg aggccaagag agcagaaaga
    15481 gaagcaagca atcctcagtt gacacaggta tctgcagatt tcataaatgc catggatctc
    15541 tggaaggatt aatccatgca agtaggcttg aaatccgagt aagatttgca agctgtgtat
    15601 aattgtgata gaataaatag aaaataaatt gaaaaaagag gtatgtgaaa tgtcacgtaa
    15661 accatttatc gctggtaact ggaaaatgaa caaaaatcca gaagaagcta aagcattcgt
    15721 tgaagcagtt gcatcaaaac ttccttcatc agatctggtt gaagcaggta tcgctgctcc
    15781 agctcttgat ttgacaactg ttcttgctgt tgcaaaaggc tcaaacctta aagttgctgc
    15841 tcaaaactgc tattttgaaa atgcaggtgc tttcactggt gaaactagcc cacaagtttt
    15901 gaaagaaatc ggtactgact acgttgttat cggtcactca gaacgccgtg actacttcca
    15961 tgaaactgac gaagatatca acaaaaaagc aaaagcaatc tttgcgaacg gtatgcttcc
    16021 aatcatctgt tgtggtgaat cacttgaaac ttacgaagct ggtaaagctg ctgaattcgt
    16081 aggtgctcaa gtatctgctg cattggctgg attgactgct gaacaagttg ctgcctcagt
    16141 tatcgcttat gagccaatct gggctatcgg tactggtaaa tcagcttcac aagacgatgc
    16201 acaaaaaatg tgtaaagttg ttcgtgacgt tgtagctgct gactttggtc aagaagtcgc
    16261 agacaaagtt cgtgttcaat acggtggttc tgttaaacct gaaaatgttg cttcatacat
    16321 ggcttgccca gacgttgacg gtgcccttgt aggtggtgcg tcacttgaag ctgaaagctt
    16381 cttggctttg cttgactttg taaaataatc agtaagtagc aaaagctagg tggaacagca
    16441 ttcagatgtc tgttacattt tttataggag aggaaagatt gaaaacaaaa attggattag
    16501 caagtatctg tttactaggc ttggcaacta gtcatgtcgc tgcaaatgaa actgaagtag
    16561 caaaaacttc gcaggataca acgacagctt caagtagttc agagcaaaat cagtcttcta
    16621 ataaaacgca aacgagcaca gaagtacaga ctaatgctgc tgcccactgg gatggggatt
    16681 attatgtaaa ggatgatggc tctaaagctc aaagtgaatg gatttttgac aactactata
    16741 aggcctggtt ttatattaat tcagatggtc gttactcgca gaatgaatgg catggaaatt
    16801 actacctgaa atcaggtgga tatatggccc aaaacgagtg gatctatgac agtaattaca
    16861 agagttggtt ttatctcaag tcagatgggg cttatgctca tcaagaatgg caattgattg
    16921 gaaataagtg gtactacttc aagaagtggg gttacatggc taaaagccaa tggcaaggaa
    16981 gttatttctt gaatggtcaa ggagctatga tgcaaaatga atggctctat gatccagcct
    17041 attctgctta tttttatcta aaatccgatg gaacttatgc taaccaagag tggcaaaaag
    17101 tgggcggcaa atggtactat ttcaagaagt ggggctatat ggctcggaat gagtggcaag
    17161 gcaactacta tttgactgga agtggtgcta tggcgactga cgaagtgatt atggatggtg
    17221 ctcgctatat ctttgcggcc tctggtgagc tcaaagaaaa gaaagatttg aatgtcggct
    17281 gggttcacag agatggtaaa cgctatttct ttaataatag agaagaacaa gtgggaaccg
    17341 aacatgctaa gaaagtcatt gatattagtg agcacaatgg tcgtatcaat gattggaaaa
    17401 aggttattga tgagaacgag gtggatggtg tcattgttcg tctaggttat agcggtaaag
    17461 aagacaagga attggcgcat aacattaagg agttaaaccg tctgggaatt ccttatggtg
    17521 tctatctcta tacctatgct gaaaatgaga ccgatgctga gaatgacgct aaacagacca
    17581 ttgaacttat aaagaaatac aatatgaacc tgtcttaccc tatctattat gatgttgaga
    17641 actgggaata tgtaaataag agcaagagag ctccaagtga tacagacact tgggttaaaa
    17701 tcatcaacaa gtacatggac acgatgaagc aggcgggtta tcaaaatgtg tatgtctata
    17761 gctatcgtag tttattacag acgcgtttaa aacacccaga tattttaaaa catgtaaact
    17821 gggtagcggc ctatacgaat gctttagaat gggaaaaccc ttattattca ggagaaaaag
    17881 gttggcaata tacctcttct gaatacatga aaggaatcca agggcgcgta gatgtcagcg
    17941 tttggtatta agcgatgatt tgaaagaggg atgtgatagt agcaccctct ttttctttgt
    18001 tttatgatag ttcatcctcg agtaaattca agatcttgct cggaaatgaa gcttatatag
    18061 tagattgaat atagacaaag accttgtgat tggtaaaaca ttttagaaat tcatttacct
    18121 ttcctaatcg acttggtttc atcttatttc aatctattat agtattgggg aatttcttca
    18181 aaccacatca gcttggtcag ttctacctgc gacctcaaaa cttgtgcttt ggtcaagctg
    18241 ggtttagttt cctagtttgc tgatggattt ccattgacta taagcatcca accctctttt
    18301 ttgtcttcta aagaattctt aaattatcag tctattgcaa cttttctcat ataagttctt
    18361 tgtcttgcta ttagttttcc ttagtagtat actaaggtag taatcattaa gaagtggtta
    18421 caaaaaataa tgaatgaggt aaagaaaatg gtagaattga aaaaagaagc agtaaaagac
    18481 gtaacatcat tgacaaaagc agcgccagta gcattggcaa aaacaaagga agtcttgaac
    18541 caagctgttg ctgatttgta tgtagctcac gttgctttgc accaagtgca ctggtatatg
    18601 catggtcgtg gtttccttgt atggcatcca aaaatggatg agtacatgga agctcttgac
    18661 ggtcaattgg atgaaatcag cgaacgcttg attacactcg gtggaagccc attctctaca
    18721 ttgacagagt tccttcaaaa tagtgaaatc gaagaagaag ctagtgaata ccgtaatgtt
    18781 gaagaaagct tggaacgtgt tcttgttatc taccgttact tgtcagaact tttccaaaaa
    18841 ggtttggatg tcactgatga agaaggtgac gatgtgacaa acggtatctt tgcaggcgct
    18901 aaaactgaaa cagataaaac aatttggatg cttgcagccg aacttggaca agcacctggt
    18961 ttgtaagaaa taaggaaaca tagataaatc tgtaggaaat ttcttacaga ttttttctat
    19021 tttgtaagct attccaaacc agtctttttt tgagtttttt gataaaatag tactatcagt
    19081 gaaaaggatg gaagtatgac taagaaaatc gtagctattt gggcccagga tgaagagggt
    19141 gtgattggta aggaaaatcg tctgccttgg catttgccag cagaattgca gcactttaaa
    19201 gaaacaactc tgaatcatgc tatcttgatg gggcgtgtga cctttgatgg gatggggcgt
    19261 cgcttgcttc caaaacggga aaccttgatt ttgacgcgta atccggaaga aaagatagat
    19321 ggggttgcta cttttcagga cgtccagtct gttcttgact ggtatcaggc tcaagaaaag
    19381 aatctctaca ttattggtgg gaagcaaatt tttcaggctt ttgaacctta ccttgatgaa
    19441 gtgattgtca ctcacattca tgctcgtgtg gaaggagata cctatttccc tgaagaactt
    19501 gacttgtctc tttttgagac agtttcaagc aaattttacg ccaaagatga gaagaatcct
    19561 tatgatttta ccatccaata ccgcaagaga aaggaactct aatggaacgg agtttatttg
    19621 gtctattcac ggcttttctg tgtttcatct gctttctggc aggagcacaa gcttttcgta
    19681 aaaagcgtta cgggctttct atcctccttt ggttaaatgc ctttaccaat ctggtcaata
    19741 gtattcatgc tttttacatg accttatttt agatagaatg acagtataga atggaaggaa
    19801 atcatgtcta caaatagaaa aaatgatatg atggtttatt gctcattttg tggcaaaaac
    19861 caagaagaag tacaaaaaat aattgctggc aacaatgctt ttatttgtaa tgaatgcgtg
    19921 gagttagctc aggaaatcat tcgagaagaa ttggttgagg aagtcttggc agacttgtct
    19981 gaggtgccaa aaccaattga actcctccat atcttgaacc actatgtaat tggtcaagat
    20041 cgtgccaagc gtgccttggc agtggcggtt tataaccact acaaacgcat caatttccac
    20101 gatacacgcg aagagtcaga agatgtagat ttgcagaagt caaacatttt gatgattggc
    20161 ccaactggtt cagggaaaac tttccttgcc cagaccttgg ctaagagctt gaatgtgcct
    20221 tttgctattg cggatgcgac agctctgacg gaggctggtt atgtgggtga ggatgtggaa
    20281 aatatcctcc tcaaactctt gcaggttgct gactttaaca tcgaacgtgc agagcgtggc
    20341 attatctatg tggatgaaat tgacaagatt gccaagaaga gtgagaatgt gtctatcaca
    20401 cgtgatgttt ctggtgaagg ggtgcaacaa gcccttctca agattatcga gggaactgtt
    20461 gctagcgtgc cgcctcaagg tggacgcaaa catccacaac aagagatgat tcaagtggat
    20521 acaaaaaata tcctcttcat cgtgggtggt gcttttgatg gtattgaaga aattgtcaaa
    20581 caacgtctgg gtgaaaaagt catcggattt ggtcaaaaca ataaggcgat tgatgaaaac
    20641 agctcatata tgcaagaaat catcgctgaa gacattcaaa aatttggtat tatccctgag
    20701 ttgattggac gcttgcctgt ttttgcggct cttgagcaat tgaccgttga tgacttggtt
    20761 cgcatcttga aagagccaag aaatgccttg gtgaaacaat accaaacctt gctttcttat
    20821 gatgatgttg agttggaatt tgacgacgaa gcccttcaag agattgctaa taaagcaatc
    20881 gaacggaaga caggggcgcg tggacttcgc tccatcatcg aagaaaccat gctagatgtt
    20941 atgtttgagg tgccgagtca ggaaaatgtg aaattggttc gcatcactaa agaaactgtc
    21001 gatggaacgg ataaaccgat cctagaaaca gcctagaggt gactatggaa cttaatatac
    21061 acaatgctga aatcttgctc agtgcagcta ataagtccca ctatccgcag gatgaactgc
    21121 cagagattgc cctagcaggg cgttcaaatg ttggtaaatc cagctttatc aacactatgt
    21181 tgaaccgtaa gaatctcgcc cgtacatcag gaaaacctgg taaaacccag ctcctgaact
    21241 tttttaacat tgatgacaag atgcgctttg tggatgtgcc tggttatggc tatgctcgtg
    21301 tttctaaaaa ggaacgtgaa aagtgggggt gcatgattga ggagtactta acgactcggg
    21361 aaaatctccg tgcggttgtc agtctagttg accttcgtca tgacccgtca gcagatgatg
    21421 tgcagatgta cgaatttctc aagtattatg agattccagt catcattgtg gcgaccaagg
    21481 cggacaagat tcctcgtggt aaatggaaca agcatgaatc agcaatcaaa aagaaattaa
    21541 actttgaccc aagtgacgat ttcatcctct tttcatctgt cagcaaggca gggatggatg
    21601 aggcttggga tgcaatctta gaaaaattgt gaggaaaaga aaatggcaaa aacaattcat
    21661 acagataagg ccccaaaggc tatcggaccc tatgttcaag gaaaaatcgt tggcaacctt
    21721 ttgtttgcta gcggtcaagt tcccctatcc cctgaaactg gggaaattgt aggagagaat
    21781 atccaagaac agacagagca agtcttgaaa aacatcggtg ctattttggc agaagcagga
    21841 acagactttg accatgttgt caaaacaact tgcttcttga gcgatatgaa cgactttgtt
    21901 ccttttaatg aggtttacca aacggccttc aaagaggaat tcccagctcg ttcagctgtg
    21961 gaggtagctc gtcttcctcg tgatgtaaaa gtcgaaattg aagtcatcgc agagattgga
    22021 taagctagtt gaagtttggt gttgccaaac ttcttttgat ataaggagaa aaagatgaca
    22081 aagaaacaac ttcacttggt gattgtgaca gggatgagtg gcgcagggaa aactgtagcc
    22141 attcagtcct tcgaggatct aggttatttc accattgata atatgccgcc agctctcttg
    22201 cctaagtttt tgcagctggt tgaaattaag gaagacaatc ctaagttggc cttggtagtg
    22261 gatatgcgta gccgttcttt cttttcagag attcaagctg ttttggatga gttggaaaat
    22321 caagatggtt tggatttcaa aatcctcttt ttggatgcgg ctgataagga attggtcgct
    22381 cgttacaagg aaaccagacg gagtcaccca ctagcagcag acggtcgtat tttagatgga
    22441 atcaagttgg aacgtgaact cttggcacct ttgaaaaata tgagccaaaa tgtggtggat
    22501 acgactgaac tcactccacg tgagctgcgc aaaacccttg cagagcagtt ttcagaccaa
    22561 gaacaagccc agtctttccg tatcgaagtc atgtctttcg gatttaagta tggaatcccg
    22621 attgatgcgg acttggtctt tgatgtccgt ttcttgccaa atccctatta tctaccagaa
    22681 ctgagaaacc aaacgggtgt ggatgaacct gtttatgatt atgtcatgaa ccatcctgag
    22741 tcagaagact tttatcaaca tttattggcc ttgattgagc cgattctgcc aagttaccaa
    22801 aaggaaggta agtccgtttt gaccattgcc atgggatgta cgggtggaca acaccgtagt
    22861 gtggcatttg ctaaacgctt ggcgcaggac ttatccaaga attggtctgt taatgaaggg
    22921 catcgcgaca aagaccgcag aaaggaaacg gtaaaccgtt catgagaaaa ccaaagataa
    22981 cggtgattgg tggagggact ggaattcccg tcattctaaa aagtctgcgg gaaaaagatg
    23041 tggaaatcgc agctatcgtg acggtggcag atgatggtgg ttcttcaggt gaactccgaa
    23101 aaaatatgca acagttgaca ccgccaggtg atcttcgtaa tgtccttgtg gccatgtcgg
    23161 atatgcctaa gttttatgag aaggtctttc agtatcggtt ctctgaggat gccggagcct
    23221 ttgctggcca tccattggga aatctcatca ttgctggctt gtcagaaatg cagggttcaa
    23281 cctataatgc catgcagtta ttgagcaaat ttttccatac aacagggaaa atttatcctt
    23341 ccagtgacca tcctttgacc cttcatgcag tctttcagga tgggacagaa gtggttggag
    23401 agagtcatat tgtagaccat cgaggcataa ttgacaatgt ctatgtgact aatgctctaa
    23461 acgatgatac gcctctggcc agccgtcgag tagtgcagac catccttgaa agtgacatga
    23521 ttgtcctagg gccaggttcc ctctttacct ctattttgcc caatatcgtg attaaggaaa
    23581 ttgggcgggc tcttttggaa accaaggcag aaattgccta tgtctgcaat attatgaccc
    23641 aacgtggaga gacggaacac tttacagata gcgaccacgt ggaagtcttg catcgtcacc
    23701 ttggtcgccc ttttatcgac actgtcttgg tgaatattga aaaagtgcct cagaaataca
    23761 tgaattccaa ccgttttgat gaatacttgg tgcaagtgga acacgatttt gtaggtcttt
    23821 gtaagcaagt ttcgcgcgtg atttcatcta acttccttcg tctggaaaat ggcggtgcct
    23881 tccacgatgg agatttgatt gtggacgagt tgatgcgcat tatacaggtg aaaaaatgag
    23941 tttcacagta gcagtaaaag aagaaatcct gggccaacac catctgagcc ggcatgaatt
    24001 atctgccatt atcaaaatgt ctggtagcat cggtctctcg acttcgggct tgactttgtc
    24061 agttgtgaca gaaaatgcca aactggcccg tcacctctat gagtcctttc tccatttcta
    24121 tgaaatcaaa tctgaaattc gtcaccacca acggagcaat cttcgcaaga atcgcgtcta
    24181 taccgttttt acagatgaaa aggtgcagga tttgttaagt gatttgcact tggcagactc
    24241 tttctttggc ttggaaacag gtattgatga ggcgatttta tcggatgagg aagcaggtcg
    24301 tgcctatctc tgtggcgctt tcttggcaaa tgggagcatt cgtgaccctg agtcaggcaa
    24361 gtaccagttg gaaatcagtt ctgtttatct ggaccacgcg caaggaattg cctcccttct
    24421 ccaacagttt ttactggatg ccaaggtgct tgagcgcaag aagggggctg tgacctatct
    24481 ccagcgagca gaagacatta tggacttctt gatagtaatc ggagccatgc aggcacgtga
    24541 tgattttgag cgggttaaga ttttgcgaga aactcgtaac gacctcaatc gggctaataa
    24601 tgccgagaca gctaatatcg ctcggacagt ttctgccagc atgaagacca ttaacaatat
    24661 cagtaaaatc aaagatatca tgggcttaga aaatttgcca gtagatttgc aggaagtggc
    24721 gcaactgagg attcagcacc cagactactc tatccagcag ttagcagata gcctcagcac
    24781 ccctctgacc aaaagtggtg tcaatcacag actcagaaaa atcaataaga tagccgatga
    24841 attataaaac cacgaatcct atgtgactcg tggttctttt ttataaacta gtagagtgtt
    24901 ttggttgtac tttttgttca gggtcaatgt agttgatagc gttgttgaca gcagttggag
    24961 cttctccgag gcctgtcgca atcagatcaa tttttccgtc atagtagcag cagtcaccga
    25021 tagcatagat acctgcttgg ctggattcct gtttgctgtt gacgataatc ttgtgacggt
    25081 tgaggtcgag cccccagttt ttaaggttac cgacagaaga tttgaaacca tagttgacaa
    25141 agaggtggtc taggtcaatg gtttcagttt catcagattt gacttttgtg atttcaagtt
    25201 tatcaagtgt ttttccattt ccaaggagtt ggctaggggc gaatggtgtc ttgatggtta
    25261 cagatgattc ttgcaaggct tgaacactgt gttccaaggc acggaaatta tctctgcggt
    25321 gaacaagggt agttggtgcg attttttcaa aagccaaagc ccaatccaca gccgagtctc
    25381 ccccaccaag aatcgtcact ttcttaccag cgtattgctg aatgttagaa acgtggtagt
    25441 ggatattttc atagccctca accccttcaa gttccagcgg acgtggtttg aaggcaccgc
    25501 cacccatagc gatgatgact gttttagtca agtgacttcc tttagaagtt gtgatggcaa
    25561 attcttcttc ttgtttgtca atctcaagaa ccgtttcatt gagatgaata ggggtatcaa
    25621 atccatttag ctgttcaatc aagcggttag tcaactcttc tccagtcagg tttgggaagc
    25681 ctggtacgtc taggatttcc ttttcagggt agagaatagc aggttgtcca cctagctggg
    25741 gaagagagtc gatgatttga accttggctt ggcgtaggtg ggcataaaag gctgcaaaaa
    25801 gcccgacagg accaccaccc acaatggtaa tatcatagag ttgagacata gtttctcctt
    25861 tgttttttct agtcagttta ttttatcata tttttgttca atgtaaactg gactaggata
    25921 gggaaaaaaa tgccagaaaa tggtataata ggacgaaagt gttttgatag ggaggatatc
    25981 agggatgaat tttcaacaat tatccaatct gcaatattgg accagtttgt ttgcaagtcc
    26041 atggacgata gctatcaatc tgattgatat tttgattgtt gcttatattt tataccattt
    26101 tacaaaagct attgcaggaa ccaagattat gattttggta cgtggagttt tggtgtttat
    26161 tttagctcaa atccttgcaa atatgattgg tttgactacg atttcttggt taatcaatca
    26221 aattattact tatggggtta ttgcggcggt tgttatcttc tctccagaga ttcggactgg
    26281 tttggaacgt ttgggaagag cgacagattt cttttccaat gcccctatta gtgctgagga
    26341 acagatgatt cgtgcctttg ttaagtctgt tgaatacatg agtcctcgta aaatcggggc
    26401 cttggttgct attcagcgtg tacgtacctt gcaggagtat atttcgacag gaattccctt
    26461 ggatgctaag atttctgcag aacttctcat taacattttt attcccaaca ctcccctaca
    26521 tgatggtgcg gtgattatca aagaagaacg tatcgctgtg acgtctgcct atctgccctt
    26581 gacaaaaaac acagggattt ccaaggaatt tgggaccaga caccgggcgg ctatcggttt
    26641 atcagaagtc tcagatgcct tgacttttgt tgtatcagag gaaacgggag gaatttcgat
    26701 aacctataat ggaaggttta agcacaacct aacacttgat gaatttgaaa cagaattacg
    26761 tgaaatctta cttccaaaag aggaagtggg tcttagtttt aaagaacgat tgctaggagg
    26821 atggaaacat gaaaaaaaat agtttatata tcatatcctc actctttttt gcttgtgtct
    26881 tatttgtcta tgctacggcg acgaattttc aaaacagtac cagtgctagg caggtaaaaa
    26941 cggaaaccta tactaataca gtaacaaatg tccctattga catacgctat aatagtgata
    27001 agtattttat tagcggtttt gcttcagaag tatcagtggt cttgactggt gcaaatcgcc
    27061 tatcgctagc tagtgaaatg caagaaagta cacgtaaatt caaggttact gctgacctaa
    27121 cagatgccgg tgttggaacg attgaagttc ctttgagcat tgaagattta cccaatgggc
    27181 tgaccgctgt ggcgactccg caaaaaatta cagtcaagat tggtaagaag gctcagaagg
    27241 ataaggtaaa gattgtacca gagattgacc ctagtcaaat tgatagtcgg gtacaaattg
    27301 aaaatgtcat ggtgtcagat aaagaagtgt ctattacgag tgaccaagag acattggata
    27361 gaattgataa gattatcgct gtcttgccaa ctagcgaacg cataacaggt aattacagtg
    27421 gttcagtacc tttgcaggca atcgaccgca atggtgttgt cttaccggca gttatcactc
    27481 cgtttgatac aataatgaag gtgactacaa aaccagtagc accaagttca agcacatcaa
    27541 attcaagtac aagcagttca tcggagacat cttcgtcaac gaaagcaact agttcaaaaa
    27601 cgaattaaaa atagaaaagg attttataac aatgggtaaa tattttggga ctgatggagt
    27661 ccgtggagaa gctaacctag aactaacacc agaattagcc tttaaactag gacgttttgg
    27721 aggctatgtt cttagtcaac atgaaacgga agcgccgaaa gtctttgtag gacgtgacac
    27781 acgtatttca ggggaaatgc tggaatcggc cttggtggca ggtctccttt cagtagggat
    27841 tcacgtatac aaacttggtg tccttgcaac accagcagta gcttacttgg ttgaaactga
    27901 aggagcaagt gccggtgtca tgatttctgc tagccacaac ccagcccttg ataacggaat
    27961 caagttcttt ggcggtgatg gcttcaaact agatgatgaa aaagaagcag aaattgaagc
    28021 cttgctagat gctgaggaag acactcttcc tcgtccaagt gcagaaggct taggaatctt
    28081 ggtagattat ccagaaggct tgcgtaagta tgaaggatac cttgtttcaa ctggaactcc
    28141 tcttgatgga atgaaggttg ccttggatac agctaatgga gcagcttcta ccagtgcccg
    28201 tcaaatcttt gcagaccttg gtgcccaatt gacggttatc ggggaaacac cagacggtct
    28261 taacatcaac cttaatgttg gttcaacaca tccagaagcc cttcaagaag tggtcaaaga
    28321 aagtgggtca gctattggtt tggcctttga tggagacagt gaccgcttga ttgctgttga
    28381 tgagaatggt gacatcgtcg atggtgacaa gattatgtac atcatcggaa aatacctttc
    28441 tgaaaaagga caattggctc aaaatacaat tgtgacaact gttatgtcta accttggttt
    28501 ccacaaggcc ttgaatcgcg aaggtattaa caaggcagtt actgcagttg gtgaccgcta
    28561 cgttgttgaa gaaatgagaa aatcaggcta caaccttggt ggtgaacagt ctggtcacgt
    28621 tatcttgatg gattacaata ccacaggtga tggtcaatta tcagcagttc aattgactaa
    28681 aatcatgaag gaaactggta agagcttatc agagttggcg gcagaagtaa cgatttatcc
    28741 acaaaaatta gttaatatcc gagtggaaaa cgtcatgaag gaaaaggcca tggaagtgcc
    28801 agctatcaag gccatcatcg agaagatgga agaagaaatg gcggggaacg gccgtatcct
    28861 tgttcgtcca agtggaacag agcccctctt gcgtgttatg gcagaagcgc ctacaacaga
    28921 agaagtagac tactatgttg ataccatcac agatgtagtt cgtgctgaaa ttgggattga
    28981 ttaaatccta gaaaactaga tgaaaataaa aaattatggt acaatagctt ataatattgt
    29041 agccgatgga gaaagacatg aatcttaaac gtgaacaaga atttgttagt cagtatcatt
    29101 ttgatgcgcg taattttgaa tgggaaaatg aaaatggagc tcctgaaacc aaggtggatg
    29161 tgaatttcca attgctccaa catgaccaag aaaatcaagt gacttccttg attgtcatct
    29221 tgagctttat gattgtattt gataagtttg tcattagtgg aacaatctca caagtaaacc
    29281 atatcgatgg ccgtattgtc aatgaaccaa atgaattgaa ccaagaagag gtggaaacct
    29341 tggctcgtcc atgtttgaac atgctcaatc gtttgactta cgaagtgact gaaattgcat
    29401 tagacttacc aggaattaat ttggagttct aatatgaaat tagctgtttt cacagattcc
    29461 tctgcttatc tcagtgcaga gaccttgcaa agagaagact tgtttgtctt ggatattcct
    29521 gtcaatattg atggtgagga atatgtcgaa ggcatcaatc tgtctgctga ggaattttac
    29581 caaaaaatgg ctcaggcttc tgaattgcct aagaccagtc aaccaagtat tgccaagtta
    29641 gatgaaatct taacttcgct caaagaacaa ggctatacac atgccttggg gcttttccta
    29701 tcttctggaa tttcaggttt ttaccaaaat atccagtata tggtcgatga ctatgagggc
    29761 ttaaccattg ctttcccaga cactttgatt acaagtgctc ccctaggcat catggttgaa
    29821 agcgtcttta attggcgtga tcagggcgat gattttgcca gcattcagga taagctagcc
    29881 attcaaatca gccgtacgtc agcctttatc atggtagatg acttggatca tttggtaaaa
    29941 ggtggacgtc tttcaaatgg ggctgccatt ttgggcaatt tgcttagcat taagccaatc
    30001 ctttatttta acgatcaagg tgtgattgaa gtttacgaaa aagttcgtac tgaaaagaag
    30061 gccaccaagc gcttaattga aattatcaag gaaacaacgg cttcaggtca ataccgggtc
    30121 attgtcattc atgggaatgc tcctgaaaag gctgaagaat tgcgtcagca tttgcttgat
    30181 tttggcttgg gttcggatgt ttcacttgct acatttggta gtgtcattgg aacgcaccta
    30241 ggagcaggaa gtattgctct gggttatatt ccagtgattt agttggcgct tctaggctag
    30301 ttaagatgcc ttgtatctta gcaattgaac acggactacc tgcttcttga aaaaagatgc
    30361 ctgtcttgcc tttcgtggaa agtcagtgcc attccctatt tttcaggggc agctaaggtc
    30421 ctttgtatct tgataattga acacgcctgg aaccctgtgt gaaaaagata gttcttccaa
    30481 gaagtagaca cttcttgatt ggaattccta ttttcacttt gtgttcttac ggactttgta
    30541 tcttagacag gagtagagat gagtattcga gtaattattg ccggttttaa gggaaagatg
    30601 ggccaggctg cttgtcagat ggtattgact gatccagact tggacttggt agcagttttg
    30661 gatccttttg agtctgagtc agaatggcag ggtattcctg ttttcaagga taaggctgat
    30721 ttagcttgtt ttgaagcgga tgtctgggta gattttacta ctccagctgt tgcctacgaa
    30781 aatacacgtt ttgctcttga aaatggcttt gctccagtag ttggaacgac tggtttcacg
    30841 agtgaagaaa ttgcagagct aaaagaattt tctcgtaccc aagacttggg tggcctgatt
    30901 gcccctaact ttgccttggg tgctgtctta ctcatgcaat ttgcgacgca ggctgccaaa
    30961 tatttcccaa atgtggagat tattgagctc catcatgaca agaaaaagga tgctccgagt
    31021 ggaacagcca ttaaaacagc tgagttgatg gcagagattc gagagtcaat tcagcaaggt
    31081 gcagcagatg aggaagagct gattgctggt gctcgtggtg ctgactttga tggtatgcgc
    31141 atccactcag ttcgtttgcc aggtttggta gcccatcagg aagtcatctt tggcaatcaa
    31201 ggagaaggat tgaccctccg tcatgactcc tatgatcgca tctccttcat gacaggagtc
    31261 aatttgggaa ttaaagaagt tgtcaagcgt catgagcttg tctatggatt agaacactta
    31321 ttatgagatt aatgcaaatg ccttctgaat ttcagaaggc tttaccagta ttagaaaaaa
    31381 ttaaagaagc aggctttgag gcttattttg ttgggggctc tgttcgagat gcccttctcc
    31441 atagccctat ccacgatgtg gatattgcga cgtcttctta tccagaagag accaagcaga
    31501 tttttccgcg aacagccgat atcggaatcg agcatggaac cgtcttggtc ttagatgggg
    31561 atgaggagta tgaggtaaca acctttcgga cagaggatgt ctatgtggac tatcgcagac
    31621 ccagtgcggt ttcctttgtg cgctcgctag aagaagacct caaacgccgt gatttcacag
    31681 tcaacgcctt tgccttggat gagacaggag aaatcgttga cttgttccat ggtttagaag
    31741 atttggaaaa gcaagtcttg cgagcagttg gagtggctag tgagcgtttc aacgaagatg
    31801 ctttacggat tatgcgtggt ttccgttttc aggctagtct tggttttgca cttgaaccag
    31861 aaacatttaa agctatgaag accttgacgc cgcttttgga gaacatttct gtagagcgta
    31921 ccttcgtcga gtttgataaa ctcttgctgg ctccattttg gagaaggggg ttggcttcca
    31981 tgattgagag tcaagcttat gactatctcc ctgatatggc atctagccag gacaagctca
    32041 acagactgtt tgatttggag actgatttta cttttgaatc ctctgaacaa gcctgggcgg
    32101 ctttactatg ggctttggag attgaaaatg cgcagtcatt tttgaaatct tggaagacct
    32161 cacgccagtt tgccaagcaa gttcaggatt tgctgattat tttggctctg cgtgaaaatg
    32221 gagaattgag caagcgagat tgttatcgct ttgacataga tttgctttta caggctgaaa
    32281 atcttcgtca agctcaagga aaagaagtca acccacaagc catcacagaa aaataccaaa
    32341 gcttgactat ccatgacaag aaagagattc agattaatgg cggtattttg atcaaggaat
    32401 atggctatca gccaggccca gacttgggag agattttaac agagattgag tttgccattg
    32461 tcgatggaga attggagaat aatcgtgaag ccatccatgc ttacctgagg gagaaaaaat
    32521 gagtgatttt atcgttgaaa aactaagtaa atctgttggt gacaagaccg tttttaggga
    32581 tatttccttt attatccatg acttagacag aattggttta atcggtgtca atgggactgg
    32641 caagaccacc cttttggacg tcctttctgg tgtttctggc tttgatgggg atgtcagtcc
    32701 tttttcagct aaaaatgatt accagattgg ttacttgact caggatcctg attttgatga
    32761 tagaaagaca gttttggata cgattctatc tagtgaactc aaggaaatcc agctcattcg
    32821 tgagtatgaa ttgattatgc tcgactatag cgaggacaag caggcgcgtt tggaacgtgt
    32881 catggcagag atggactctc tccaagcttg ggaaatcgag agtcaggtca agaccgttct
    32941 tagcaaattg ggcattcaag acttatctac tcctgttggg gaattgtcag gtggtctgag
    33001 aagacgggta cagttggcac aagtcttact tggcaaccac gacctcttgc ttttggatga
    33061 gccgaccaac catctggata ttgcgattat tgagtggctg accctctttt tgaaaaattc
    33121 taagaagacc gtccttttta tcactcacga tcgttatttc ttagacgctt tgtcaacacg
    33181 gattttcgag ttggagcgag caggcttgac agaatatcag ggcaattacc aggactatgt
    33241 tcgccttaag gcagaacagg acgagcgcga tgcagctcta cttcataaaa aagaacaact
    33301 ctacaaacaa gaactggtct ggatgcgcag acaaccgcag gcacgtgcga ccaagcaaca
    33361 agctcgtatc aatcgtttcc atgatctgaa aaaggaagtt tcaggcagta gtgctgagac
    33421 agacttgact atgaactttg aaaccagtcg gattgggaag aaagtcatcg agtttcaggc
    33481 tgtttccttt gcctatgaaa ataagcccat tttgcaagat tttaatctct tagttcaggc
    33541 taaagaccgt attggaattg ttggggacaa tggtgttgga aaatcaaccc tacttaacct
    33601 gattgcagga agtcttgagc cgacagcagg acaagttgtg attggggaaa ctgttcgcat
    33661 cgcctatttc tctcaacaaa ttgagggttt ggatgaaagc aagcgtgtga tcaattacct
    33721 gcaggaagtg gcagaggagg tcaagaccag tggtggttct acgacttcca tcgctgagtt
    33781 gctggagcaa ttcctcttcc cacgttcgac gcatgggacc ttgattgaga aattgtcagg
    33841 gggtgagaaa aaacgtcttt atctcctcaa actgcttttg gaaaaaccaa atgttcttct
    33901 tttagacgag ccaaccaatg acctagatat tgcaactttg acagtcttag agaatttctt
    33961 gcaaggtttt gcaggtcccg ttttaacagt cagtcacgac cgctatttct tggataaggt
    34021 agcgaccaag attctcgctt ttgaggatgg caagattcgt cctttctttg gtcattacac
    34081 cgactatctt gatgaaaaag cttttgaaac agatatggcc aatcaagtgc aaaaggccga
    34141 aaaggaaaaa gtggtcaagg ttcgagaaga caagaaacgc atgacctacc aagaaaagca
    34201 ggagtgggca agtattgaag gtgatattga aaccttggaa aaacgtatcg ctgctattga
    34261 agaggaaatg caggctaacg gctctgactt tggtaagctg gctactctcc aaaaagaatt
    34321 ggatgagaaa aatgaagcac tccttgaaaa atacgaacgc tatgagtatc tcagtgaatt
    34381 tgatagttaa tactattcga aaatcaaagt gtaaactatg tcggcttcac attgccgact
    34441 caagtacagc ctgtggccgg cttcctagtt tgcactttga tttttattga gtataaaaga
    34501 atagaaaaat cccatctcat gaacggattt ctctattctt ttttggtttc ttgatgaaag
    34561 atattttgcc aggtttcgtg gcgacgccag atactggtat ggatgatacc atctaactca
    34621 tagcagatga gtttggtttt ttgactgatg gaagtaattt gaatgtcctt gatagcagaa
    34681 tttaactctt ttttggtctt ataagcctct ttatccatct gctctccatc ttggcgaata
    34741 tagacaaaat catcagtcaa gagttcttct agttggtttc cttggtcaat caattgttca
    34801 cgcataagca attttttata gacattgtct aaaatttcat cctcagggat aggtgctggt
    34861 tcgatatgga catcggtatc aaagacgcca aaacgattct ccagcataga ctcgacctga
    34921 tccgcgattt catggctttc aaaaacagac aagtcaggat tcatctctag tgtaatatcc
    34981 aggtagatgt tgctaccgta ggtgcgacct ctttgcgatt tgaccttgct gattttggga
    35041 atttccatga tagccttttg gtagtcctcg agcaggcggt cgtcaaagcc atctgaaaga
    35101 ctaaaggaag actcgatgaa gatatcatag gcagtcttca agataaagaa agtgatgatg
    35161 atagcaacca gtttatccac aatcggataa ttgaaactac tagctaggat ggcaatggcg
    35221 gttccaagtg aggtaacagc gtcagaaaga ttgtccttag cagctgcttt cagcgccttg
    35281 gagttggatt tcttactgag gcgagtattg tagagataga ccacaaacat aatcgctgca
    35341 gaaatgattc ctagagttgc accaagagga tcaatgaccg tttcttcccg actgagaatc
    35401 ttttgaatgg tatctcttag aacatcgaaa ccgacataga acatgatgat agaagtgatc
    35461 aagcttgcca aatcttcaat cttccaatga ccaaaacggt ggtcacggtc tgcaggctgg
    35521 cgcgccatcc gaatcccgat taagagggcc acatttccaa tgatgtccga tacgttatta
    35581 aaaccatcgg ccaccaaact ggatgaatga aggagatgac cagttgctaa tttggctgca
    35641 gacaagatca aataggtcga aatactgata atggctccac gctcagctaa cttgagattt
    35701 gagatagatt gcttcattca acttcctttc tagtcacata gcattctacc attatactgg
    35761 ttttcaagga aaaattcaaa taaggcagtt tttactcttt gaaaactccc caaaatttgg
    35821 tataatagta ctactcaagg gagtagctgg cagaaacctg tgatagtgtc gtcattccga
    35881 attttatgct gaaaagtatg ctttccggcc ctatcttaaa cagcgagact tgttatgatt
    35941 aacaggtctc tttttgtttg tcgtgaaaag atatgacaga aagagagtct gttttgcaca
    36001 caatgtcaag gaggagacac atgtcaaaag aacaaaaacg ccaagcgttt tatactcaga
    36061 gccctgaaga ggtcttgcag gctgtggatg cgaccgagca aggtttgtcg tcaagtgagg
    36121 cggaaaagcg ccttgtcgaa tttgggcaca atgaactcga agaaggcgag aaacgatcaa
    36181 tcttggtcaa attcatcgag caatttaagg atttgatgat tatcatccta gttgcggcag
    36241 caatcttgtc agtcgtgact tctggtgggg aagatatcgc agatgccatt atcatcctag
    36301 ctgtggttat catcaacgct gcctttggtg tttaccaaga aggaaaagct gaagaagcta
    36361 ttgaagccct caaatccatg tctagtccag ttgcccgcgt tcttcgtgat ggacacatgg
    36421 cagagattga ctctaaagaa ttggtaccag gcgatatcgt tgcccttgaa gcaggtgacg
    36481 tggtaccagc ggacctacgt ttgatagaag ccaactctct taaaattgaa gaagcagcct
    36541 tgacaggtga atctgtacca gtcgaaaaag acttgtcagt cgagcttgcg acagatgctg
    36601 gtattggtga ccgtgtcaac atggccttcc aaaactcaaa cgtaacctat ggtcgtggga
    36661 tgggtgttgt tgtcaataca ggtatgtaca ctgaagttgg tcatattgct ggtatgcttc
    36721 aagatgcgga tgagactgat acaccactca aacaaaactt gaacaacctt tctaaggtct
    36781 tgacctatgc tatcttggcc attgcccttg ttacttttgt agtgggtgtc ttcattcaag
    36841 ggaaaaatcc acttggtgag ttgttgactt ctgttgccct tgccgttgca gccattccag
    36901 aaggacttcc tgctatcgtt accatcgttc tttctcttgg tactcaagtt ttggccaaac
    36961 gacattccat cgttcgtaag ttgccagcag ttgaaacact tggttcaact gaaatcatcg
    37021 cttctgataa gactggtacg ctgactatga acaagatgac agtcgaaaaa gtcttctacg
    37081 atgcggttct acatgactca gctgatgata ttgaactagg tcttgaaatg ccactacttc
    37141 gttcagttgt cttggccaat gatacgaaaa tcgatgtgga aggtaacttg attggtgacc
    37201 caaccgaaac agcctttatc caatatgcct tggacaaggg ctatgatgtc aaaggtttct
    37261 tagagaaata tcctcgtgta gctgaattgc catttgactc tgaccgtaag ctcatgtcaa
    37321 cagttcaccc attgccagat ggtcgtttcc ttgtagcagt caagggtgcg ccagaccaac
    37381 tcttaaaacg ttgtcttctt cgtgataagg ctggggatat tgctccgatt gatgagaagg
    37441 ttacaaatct cattcataca aacaattctg aaatggctca tcaagccttg cgtgtccttg
    37501 caggtgctta taagattatc gatagtattc cagaaaatct cacttctgaa gagcttgaaa
    37561 atgatttaat ttttactggt ttgattggga tgattgaccc tgaacgtcct gaagccgctg
    37621 aggctgttcg tgtggctaag gaagcgggaa tccgtccaat tatgattaca ggtgaccacc
    37681 aagacacagc ggaagccatt gccaaacgtt tgggaatcat tgacgcaaac gatacagaag
    37741 gtcacgtttt aactggtgct gaactcaatg aactgtcaga tgaagaattt gaaaaagtcg
    37801 ttggtcaata ctctgtttat gcccgtgtgt ctccagaaca caaggttcgt atcgtcaagg
    37861 cttggcaaaa acaaggtaaa gtcgttgcca tgacaggtga cggtgtcaat gacgcgccag
    37921 ctctgaaaac agccgatatc ggtatcggta tgggaatcac tggtacagag gtttctaagg
    37981 gggcttctga tatgattctt gcagatgata actttgcgac tattatcgtc gcagtggaag
    38041 aaggacgtaa ggtcttctca aacattcaaa agactattca gtacctactt tctgctaata
    38101 ctgctgaagt attaaccatc ttcctatcaa ccttgtttgg ttgggatgtc ttgcagccgg
    38161 ttcatctttt gtggatcaac ttggtaacgg ataccttccc agctatcgct cttggtgttg
    38221 aacctgcgga gcctggtgtc atgaatcata aaccacgtgg acgcaaggca agcttcttct
    38281 caggtggtgt tttgagttct atcatttatc aaggtgtact ccaagcagct cttgttatga
    38341 gtgtttatgg ccttgcgatt gcttacccag ttcatgtggg tgacaatcat gctattcatg
    38401 cagatgccct aacgatggcc tttgcaaccc ttggtttgat tcagctcttc catgcctaca
    38461 atgtcaagtc tgtctaccaa tccatcttga cagttggccc attcaagtct aagaccttta
    38521 actggtccat cttggtatct tttatccttc tcatggcaac aatcgttgta gaaccgcttg
    38581 aaggaatctt ccacgtaacc aaactagact tgtcacaatg gggaattgtt atggctggaa
    38641 gcttctcaat gattatcatc gtcgaaatcg ttaagtttat tcaacgcaaa ctcggttttg
    38701 acaagaatgc gatttaaggg aggtttcgga tgtcagcata tcaattaccg accgtatggc
    38761 aggatgaagc tagtaatcaa ggagctttta cggggctaaa cagaccaaca gcaggtgccc
    38821 gtttcgaaca aaacttgcca aaaggagaac aagcttttca gctttattca ctgggaacac
    38881 caaatggtgt gaaggttact atcttattgg aagaattact agaagctggt tttaaggaag
    38941 cggcttacga cttgtataag attgctatca tggatgggga tcaattcggc tcagactttg
    39001 tgaagctcaa tccaaattcc aagattccag ccttattgga ccagtcaggt actgaaaacg
    39061 taagagtctt tgagtctgct catattcttc tttaccttgc tgagaaattt ggagcctttt
    39121 taccaagtaa tcctgtggaa aaggtagaag ttttgaattg gctattctgg caagcaggtg
    39181 cagcaccttt tctaggtggg ggatttggac atttcttcaa ttatgctcct gaaaaattgg
    39241 aatatcctat taaccgtttt acgatggaag tgaaacgcca gttggattta ttggataagg
    39301 aattggctca gaaaccttat attgcaggca atgactatac gattgcagat attgctatct
    39361 ggtcttggta tggacagtta gttcaaggaa atctttacca aggttctgca aaattcttgg
    39421 atgcctcaag ttatcaaaat ctagtaaaat gggcagaaaa aattgccaat cgtccagctg
    39481 ttaagcgtgg attggaagta acttatacag aaattaaata gcaaaaaagt catcttcgga
    39541 tggctttttg ctacagttga gggaaagggt ttgcagttat cggcttttgt gctataattg
    39601 ctataatata gtaaaaagca agaggagtgt gaggaagtgg aaaagaaaat tgtgaaggat
    39661 atcttatttt tatctcaagt gtctcagccg gcaagtcagg aggaccttta tcttgccaga
    39721 gatttgcagg atacactctt agcaaatcgt gatacctgtg ttggtctagc tgccaatatg
    39781 attggggtgc agaagcgcgt gattatcttt aatcttggct tggttcctgt ggtcatgttt
    39841 aacccagtgc ttctgtcctt tgaaggatcc tatgaggcag aagaaggctg tttgtccttg
    39901 gtaggtgtga gatcaactaa gcgttatgaa accataaggc ttgcctatcg tgacagcaag
    39961 tggcaggaac agaccattac cttgacaggc ttcccagctc agatttgcca gcatgagctg
    40021 gatcacttgg aaggacgaat catttaggag gaaagcaaat gaaacgaata gtctttgaac
    40081 ttatttttat cgcaacgacc tggtatatct ttttaccgcc ccttaacctg accagctggg
    40141 aatttctctt cttcctctgt gggcatttgt tagttgtggc aatattattt ggctttggca
    40201 aggggataaa ccttgtcaaa acggttcatg tgcgccacgg taaggcggaa gctgccttaa
    40261 atcttgaggg tttcaaaatc aatcggttag ggaaaattct gttagcttcg attggaggaa
    40321 ttcttctctt ggcagctttg gtttccttgg taacttccag catgtttcag gctaaaaatt
    40381 atgccaatgt agtcacggtt acggaaaaag actttactga atttcctaag agtgacacca
    40441 gtaaggttcc tatcctagat agaagtactg ctgaaaaaat tggagaccgc tacttgggtt
    40501 ccctaaccga taaggtgtcg caatacgtag cggcagatac ctatacccaa ttgacaattg
    40561 atgggaaacc ttatcgggtc acaccactag aatatgcaga ccctatcaaa tggtttaaca
    40621 atcaagccaa gggaatcggt gagtatatta aggtggacat ggtaactgga aatgcggatt
    40681 tggtggactt gaagacacca atcaagtatt cagactcgga gtattttaac cgtgatgtca
    40741 aacgtcacct gcgcttgaag tacccgacca aaatctttaa aactccatct tttgaggtgg
    40801 acgatgaggg caatcctttc tatgtagcaa cggtttacca aaagcaattt ggacttgctg
    40861 ttcctcgtcc tgcttcagtc attatcttgg atgctacaaa tggagaaacc aaggaataca
    40921 gcttatcaga tgttccagaa tgggtggaca ggatctatcc agcagaggaa accattgagc
    40981 aaatcaacta caacggcaag tacaaggacg gtttcttgaa tgccatgatt tccaagaaaa
    41041 acgtgaccca gactaccaat ggctataatt acttgtctat cggtaatgac atctatctct
    41101 acacaggtgt gacgtcggct aatgcggatg agagtaatct tggtttcatc cttgaaaata
    41161 tgcgaacagg agaaatcact aagtatagct tggcttctgc gacagaagaa tcagcccgtg
    41221 aatcagcaga aggtgctgtt caggagaaat cctacaaagc aaccttccca atcctcatca
    41281 acctcaatga caagcctctc tacatcatgg gcttgaagga caatgctggc ttggtcaaag
    41341 agtacgccct ggtagacgca gtcgagtacc aaaatgttat cgttgctact acagtggaag
    41401 agatgctcag caagtatgcc aataaaaacg accttgaaat tgacaatgca acgacagaaa
    41461 gcatcaatgg agtagtagca gacctcaaat cagctgttat caagggagac actgtctact
    41521 tctttaaagt tgatggcaag atatacaagg tcaaggcttc agtatccgat gaccttcctt
    41581 accttgaaaa tggtaaaacc ttcgaaggtc aagtaggaaa agacaattat ctcaagacct
    41641 ttaagctacg gtaaaaatag gtttttttca gaaagtatat gttataataa ggtaaattaa
    41701 gcctaatgga ggacaaagaa atgggttttt atttgatggt tgcttcaatg ctactcggac
    41761 tgctcgcttt gaagataggt ttttctcagt tcaaggagaa aaaagataaa ttcttatcta
    41821 tcttaacaag tttagctggc acagcccttg ttctcgtggc tgtctggtta ggatggccca
    41881 aataaataga aaaacctcgg tcaaaccgag gtttttcaaa tgaatttctt ggttgtggct
    41941 aaaaaatatg ctacactatc aatatgaaaa ttttaatccc aacagcaaaa gaaatgaaca
    42001 cagacttgcc aagtatcgag gcaattcctt taaaaccaga aagtcaggcc gtgcttgatg
    42061 ccttggctct ctattctgcc agtcaattgg agagtttcta caaggtatca gctgagaaag
    42121 cggcggaaga atttcaaaat atccaagctt tgaaaaggca aactgctcaa cactatccag
    42181 ccttgaaact ttttgatggg cttatgtacc gcaacattaa gagagataag ctgaccgagg
    42241 cggaacaaga ttatcttgaa aatcatgttt tcattacctc ggctttgtac ggtgttgttc
    42301 cagtcttgtc acccatggct cctcaccgtt tggatttttt gatgaaatta aaagtcgctg
    42361 gtaagacttt gaagagccat tggaaggcag cctatgatga aactctgaag aaggaagaag
    42421 tgattttctc tctcttgtca tcagagtttg agactgtatt ttctaaggaa atcagagcaa
    42481 agatggtgac cttaaaattc atggaggata gaggcggtca gctgaagatt cactcaacta
    42541 tctccaagaa agcgcgcggg gcctttctaa cagctttaat agaaaatcaa gtacaaactg
    42601 tgggggaagc acgtcgcttg aactttgctg gatttgttta ccgagaagat ttgtcacaac
    42661 cacagggatt ggtttttgta aaggaagtat agaaatcaga tattttgtat ttggcaatat
    42721 gtatcatcag ctattttagt ttataaatga gaaaaaagcg aacaagctag tcttctgagt
    42781 gtcagaaaag tagtcttgtt cgcttttatt atgttatact cttcgaaaat ctcttcaagc
    42841 cacgtcagtg tcgccttacc gtatatatgt tactgacttc gtcagttcta tctacaacct
    42901 caaagcagtg ctttgagtag cttgcggcta gcttcctagt ttgctttttg atttttattg
    42961 agtgttagtt acttgatagc ttcgaccaag tcttgagctt gtttttcaag tgagtttagg
    43021 actgtttctt caagaaccaa ttttccgtct gcccaggcag agtcattaac acgtgcagca
    43081 gtgaaatcac caacgccttg tgtacggata aatggcaaga ggtctttgta gatagcgaaa
    43141 agttgatcgt gccctgcatt ggctacagat gatactgtga caaacttgtc ttgaagggca
    43201 gaaacgccac gtgtatcaga caagtcaagg gcacgagata gccagtcaag caagtttttc
    43261 actgtaccag ggatagagaa gttgtagact ggagagaaaa tccagatagc atccgcaacg
    43321 agaactgctt cacgagcagc agctacagct ggatgtgttg gaacttccaa atcttggctg
    43381 aagagaggaa gggctgaata atcaaggtag ctaacttccg ctttaccagc aagtgctttc
    43441 tcagcttcga gcgccatttg gtggttgaaa gaaccttgac gtagtgatcc gacgataaat
    43501 aatacttttt tagacatgat gtgtctcctt tttcttaaaa tttcgagaac tctctcgttg
    43561 ttataaaata tattacaaca aaacaaaaga acttgcaaga aatttgctca gagtttattt
    43621 gaaaattgta aaatttcgga aactctagtc atttgtgact gaaaaagtaa gaactgtttc
    43681 actttcaaaa tcggttttgt ttgaagggag aaatagaat
//
LOCUS       DAVBNZ010000011        43040 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000011 DAVBNZ010000000
VERSION     DAVBNZ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43040
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.011"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            47..117
                     /locus_tag="VQ860_000630"
     tRNA            47..117
                     /locus_tag="VQ860_000630"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:79..81,aa:Gly,seq:tcc)
     gene            153..226
                     /locus_tag="VQ860_000631"
     tRNA            153..226
                     /locus_tag="VQ860_000631"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Ile,seq:gat)
     gene            233..320
                     /locus_tag="VQ860_000632"
     tRNA            233..320
                     /locus_tag="VQ860_000632"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:267..269,aa:Ser,seq:gct)
     gene            complement(446..1381)
                     /locus_tag="VQ860_000633"
     CDS             complement(446..1381)
                     /locus_tag="VQ860_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET3119110.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1378..2238)
                     /locus_tag="VQ860_000634"
     CDS             complement(1378..2238)
                     /locus_tag="VQ860_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET3119111.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2346..4508
                     /locus_tag="VQ860_000635"
     CDS             2346..4508
                     /locus_tag="VQ860_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET3119112.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTEILVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLFYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4600..5859
                     /locus_tag="VQ860_000636"
     CDS             4600..5859
                     /locus_tag="VQ860_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3119113.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5873..6739
                     /locus_tag="VQ860_000637"
     CDS             5873..6739
                     /locus_tag="VQ860_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3119114.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIIAIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6753..7586
                     /locus_tag="VQ860_000638"
     CDS             6753..7586
                     /locus_tag="VQ860_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3119115.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7587..7667
                     /locus_tag="VQ860_000639"
                     /pseudo
     CDS             7587..7667
                     /locus_tag="VQ860_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7944..9386
                     /gene="gtfA"
                     /locus_tag="VQ860_000640"
     CDS             7944..9386
                     /gene="gtfA"
                     /locus_tag="VQ860_000640"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET3119116.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKHLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9524..10717
                     /locus_tag="VQ860_000641"
     CDS             9524..10717
                     /locus_tag="VQ860_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET3119117.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11404..13383
                     /locus_tag="VQ860_000642"
     CDS             11404..13383
                     /locus_tag="VQ860_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3119118.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVEVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13450..14946
                     /locus_tag="VQ860_000643"
     CDS             13450..14946
                     /locus_tag="VQ860_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3119119.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14946..15872
                     /locus_tag="VQ860_000644"
     CDS             14946..15872
                     /locus_tag="VQ860_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3119120.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15881..16948
                     /locus_tag="VQ860_000645"
     CDS             15881..16948
                     /locus_tag="VQ860_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119121.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16959..17885
                     /locus_tag="VQ860_000646"
     CDS             16959..17885
                     /locus_tag="VQ860_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119122.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18376..18891
                     /locus_tag="VQ860_000647"
     CDS             18376..18891
                     /locus_tag="VQ860_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3119123.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSLANTTQ
                     TPPVIFSAVTDPVSAKLVESREHPGGNVTGTSDQSSDAISTQINLIKKVLPKAKTIGI
                     LYTQSEPNSVV"
     gene            18913..19314
                     /locus_tag="VQ860_000648"
     CDS             18913..19314
                     /locus_tag="VQ860_000648"
                     /inference="COORDINATES: protein motif:HMM:NF016292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119124.1"
                     /translation="MKEKGFTVVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISST
                     METVKQVSIKHKVPVFGGSTEMIAVGDLYNYGTNYEELGRQTARMLIRVLKGEKPENI
                     AVELPEKLELHTNQEMADALGIDISKLEGKE"
     gene            19326..20203
                     /locus_tag="VQ860_000649"
                     /pseudo
     CDS             19326..20203
                     /locus_tag="VQ860_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            20216..21019
                     /locus_tag="VQ860_000650"
     CDS             20216..21019
                     /locus_tag="VQ860_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3119125.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(21052..21762)
                     /gene="treR"
                     /locus_tag="VQ860_000651"
     CDS             complement(21052..21762)
                     /gene="treR"
                     /locus_tag="VQ860_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET3119126.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            21947..23914
                     /gene="treP"
                     /locus_tag="VQ860_000652"
     CDS             21947..23914
                     /gene="treP"
                     /locus_tag="VQ860_000652"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET3119127.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24092..25717
                     /gene="treC"
                     /locus_tag="VQ860_000653"
     CDS             24092..25717
                     /gene="treC"
                     /locus_tag="VQ860_000653"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET3119128.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            25859..26107
                     /locus_tag="VQ860_000654"
     CDS             25859..26107
                     /locus_tag="VQ860_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET3119129.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26314..27108
                     /gene="racE"
                     /locus_tag="VQ860_000655"
     CDS             26314..27108
                     /gene="racE"
                     /locus_tag="VQ860_000655"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET3119130.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27105..28076
                     /locus_tag="VQ860_000656"
     CDS             27105..28076
                     /locus_tag="VQ860_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET3119131.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNLHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28052..28573
                     /locus_tag="VQ860_000657"
     CDS             28052..28573
                     /locus_tag="VQ860_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET3119132.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28570..29031
                     /locus_tag="VQ860_000658"
     CDS             28570..29031
                     /locus_tag="VQ860_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3119133.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29022..29762
                     /gene="xerD"
                     /locus_tag="VQ860_000659"
     CDS             29022..29762
                     /gene="xerD"
                     /locus_tag="VQ860_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET3119134.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            29762..30490
                     /locus_tag="VQ860_000660"
     CDS             29762..30490
                     /locus_tag="VQ860_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET3119135.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30509..31078
                     /locus_tag="VQ860_000661"
     CDS             30509..31078
                     /locus_tag="VQ860_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET3119136.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31065..31787
                     /locus_tag="VQ860_000662"
     CDS             31065..31787
                     /locus_tag="VQ860_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3119137.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLIIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            31787..32029
                     /gene="yidD"
                     /locus_tag="VQ860_000663"
     CDS             31787..32029
                     /gene="yidD"
                     /locus_tag="VQ860_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET3119138.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLSRILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(32254..33219)
                     /locus_tag="VQ860_000664"
     CDS             complement(32254..33219)
                     /locus_tag="VQ860_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3119139.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33315..34067)
                     /locus_tag="VQ860_000665"
     CDS             complement(33315..34067)
                     /locus_tag="VQ860_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3119140.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            complement(34064..35020)
                     /locus_tag="VQ860_000666"
     CDS             complement(34064..35020)
                     /locus_tag="VQ860_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET3119141.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(35010..35969)
                     /locus_tag="VQ860_000667"
     CDS             complement(35010..35969)
                     /locus_tag="VQ860_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3119142.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSEGLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36392..37093)
                     /gene="galE"
                     /locus_tag="VQ860_000668"
     CDS             complement(36392..37093)
                     /gene="galE"
                     /locus_tag="VQ860_000668"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3119143.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37495..38559
                     /gene="pepA"
                     /locus_tag="VQ860_000669"
     CDS             37495..38559
                     /gene="pepA"
                     /locus_tag="VQ860_000669"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET3119144.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKDEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38581..38877
                     /locus_tag="VQ860_000670"
     CDS             38581..38877
                     /locus_tag="VQ860_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3119145.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39559..40002
                     /locus_tag="VQ860_000671"
     CDS             39559..40002
                     /locus_tag="VQ860_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3119146.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            40006..40770
                     /locus_tag="VQ860_000672"
     CDS             40006..40770
                     /locus_tag="VQ860_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET3119147.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            40785..41513
                     /locus_tag="VQ860_000673"
     CDS             40785..41513
                     /locus_tag="VQ860_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119148.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41506..43026
                     /locus_tag="VQ860_000674"
     CDS             41506..43026
                     /locus_tag="VQ860_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET3119149.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
BASE COUNT        12455 a         7979 c         9680 g        12926 t
ORIGIN      
        1 tcggcggttc gattccgtct cgcgccattt tattgatagt atttatgcgg gtgtagttta
       61 gtggtaaaac tacagccttc caagctgttg tcgcgagttc gattctcgtc acccgctttg
      121 aactttgttc aaattaccaa gttttttaac ttgggcgcgt agctcagttg gttagagcgc
      181 acgcctgata agcgtgaggt cggtggttcg agtccactcg tgcccattaa ttggagaatt
      241 actcaagagg ctgaagagga cggtttgcta aatcgttagg tcgggtaact ggcgcaaggg
      301 ttcgaatccc ttattctccg ttttaatgag agtctgtaac tctctttttt atttttagag
      361 ccaataaaac ttcagatccg taaaacttaa ttgaattact aatctgaagt tatttttata
      421 tcgtttatat tataattgtg ttattttact tccaactatt gagagaaatt tcgccactat
      481 ttagccagat ttcttttccg ttatcacatt gaactaaaag ttttccattt tctgagatgt
      541 ctttagcaag tcccttgtag tctttttgct ctagtgtgaa agtgacttct tttcctagaa
      601 tgaatgactg ttttttgtat aggtataata gctcttctgc tggtgtttcg aagaaagcac
      661 gccagatttc tatgatcaat tcattccttg ttataggagc tgtagcttta aataagctgg
      721 cagctttttc ttttaattcc tgagggaagt ctttaatagt gaaattgata cctactccaa
      781 taatgatatc tgtgactaag ccagtttcta cagaggtcat tgcttcagta aggattcctc
      841 caattttatg attgtttaga tagatatcat tgacccattt tatgtcgaca tctattaaag
      901 ttaggttctt aatggctttg tagacagctc cagctacaag tagtgtgtag gatggtaatt
      961 tgtcataggg gagatttggt ttaagatgga gtgtcatata aataccacct tgtggtgagt
     1021 agaaggaacg ttgaaaacgg cctcggcctg ctgtttgata ggaagctaga tagagggtat
     1081 ttgcttcatg gcctaaatca attgcttctt ttgcatctag ttgtgttgat tttgtttcgg
     1141 gtttaaagct gactttaatt ggaagatttt cttctagaat ctctggaaga ataaggtcac
     1201 cattcatcag tttatatcct ctatttttga tactatcaat ttcaatgcct tcttgttcta
     1261 gtcgcttgat ggctttccaa attgctgttc ggcttaggga tagtttttct gcgatttttt
     1321 ctccgctgat atagtcggtt tctttagata ggatttggta gacagcttgg taggatttca
     1381 taatgttgcc tttcttacta gttggtattg agagtattct tttcttgtat gacttggagt
     1441 ctgattaaag tattgtttat aagctttcga aaaatggagt ggatctgaaa aacctaccga
     1501 gtatgcaatt accttgatgg actcttgggt attttcgaga agttgtctag ctcggtgcat
     1561 tcgaacgtag agtaggtatt ctttgggtga taaggtatta aattctttga atacgcttga
     1621 taagtagctt ctgtgaacgg atagttcttt tgctaaatct tgaattgtaa gtgattgagg
     1681 atagtggcta tcaattaatc gtttgcattc aagatagagt tggtgggttg atgaaatatt
     1741 cttttttttc tgattgggag caatagttcc cagatgaaac atcagttcat gaagttgtcc
     1801 catgatatgg agttgagcta attcacttga ttttgtaatc tgagcgaagc ggacaatgtc
     1861 tgagatgagt tttgcagtag tctgggtatg acaagtttca gattggatga gataggattg
     1921 atcagaaatt tgggaaagag caaaataatc aggggctttc cctccagtga ttcctaacca
     1981 gtagtaggcc caaggttctt tactatctgc ttgataaaag gttagttcct ctggttttaa
     2041 tagaaagaaa tctccttctt ttaaatcaac aattttaccc ttgtaatgaa attttccttg
     2101 tcctttagta atgtaatgta gaacgtatgt atcacgaatg gctggaccaa aagagtaatt
     2161 aggtgtgcat tcctcatatc cataaaagct tagggcaagg tcgattgttc cagtctggta
     2221 ttctgaaaaa actaacatgt gctacctcct acctaacatt ttaccatatt cttgagacat
     2281 ttttctattt tggaaagcga tttcaggtga taaaatataa tcaataaagt gatgaggtga
     2341 agtaaatggg agttaggata gagaataatc tattttatgt tgagagtaaa aatctaagtt
     2401 tgattattga aaatcgaaat ggctacttac ttttgaaaca tttaggaaag actattaaga
     2461 actataaagg ttccaatagt gtttatgaac gagaccatgc cttttcagga aatccaacgg
     2521 ctactaatcg aacctttagt ttagatactc agcgacagat ttttggacaa catggcttag
     2581 gagattttag gaaaccaacc atacaggttc agcatagtgt aactgaagta acagactttc
     2641 gatttgtaga agcaaagatt ttaaaaggtc agaatggtcc acagggctta ccttctccac
     2701 atagcatgga cgatacagag attcttgtct taatgttaga agattctaag gctcaactta
     2761 gtctgacttt gtattatact acttttaata atgatgcgac tattgctagc tacagtaaat
     2821 tagataataa tagtaatcag gaagttgtca tccataaaga tttttctttt atggctgatt
     2881 ttccagctgc agattacgaa atagtaactc tgcagggtgc ttatgctcgt gaaaagactg
     2941 ttagacgtca acaggtagaa caaggaatct tttcgattag ttcaaaccga ggtgcttctg
     3001 gtcatgctca aacaccagct cttctactat gcgaacaagg agtcacagag gatgctggga
     3061 atgtgtttgc tattcaacta atgtatagtg gcaactttga agcttttgtt caaaaaaatc
     3121 aattgaatga agttcgggtg gctattggca ttaatccaga aaacttttct tggaagttag
     3181 ctcctgagga atactttgaa acaccggtag ctttagtgac tcattcagat cagggattaa
     3241 ctggtattag tcatgaaagt cagaattttg tactgaagca cattatgcta agtgaatttt
     3301 ctaaaaaaga acgtccaatt ctaatcaata actgggaagc tacttacttt gactttcaga
     3361 gagaaaaact gttagagtta gcagatgaag ctaagaaagt tggcattgaa ctttttgtat
     3421 tagatgatgg ttggtttggc aatcgttttg atgataatcg tgctttaggt gattgggttg
     3481 ttaatgagga aaaactgggt ggaagtctag aaagtctgat ttcagctatc catgaaagag
     3541 gtttgcagtt tggactttgg ttagaacccg aaatgatttc tgtagatagt gatttgtatc
     3601 gtcaacatcc tgactgggct attcaggttc ctggctatga gcatacttat tctcggaatc
     3661 aattagtact taatcttgcc aatcctcagg tagtagaata cttgaaaagt gtcttagatc
     3721 aactcctatt ttatcatgat attgattaca ttaaatggga tatgaaccgc aatatcacta
     3781 agctagggaa tggattaact tatctagaga cacagatgca atctcatcag tacatgctgg
     3841 ggctttatga actcgtttct tatctgacag agaagcacag ccatattctc tttgagtcct
     3901 gctctggtgg tggtggacga aatgatcttg gtatgatgcg ctatttccca caagtctggg
     3961 ctagtgataa tactgatgcc attgcacgtt taccaattca atacggttca tcctatctct
     4021 atccaaccat ttctatgggg gctcatgtgt cagcagtacc gaatcatcag atgggacgaa
     4081 tgacaccatt agaaacacgt ggccttgtag caatgatggg aaatttgggc tatgaacttg
     4141 atttgacaaa tttatcagat gaagagaaag ctacgattgc taatcaggtg aacttgtata
     4201 aagaattacg accagtagtt cagttaggac agcagtatag actaattaat cctgatactg
     4261 tatccaatga agcagctgta caatttaatt acggaaatca aacgattgta acctacgttc
     4321 gcgttttatc tgttgtagag accatggaaa caactttaaa attaaaagat ttggatgaag
     4381 agggactata taaattacag gaaaatggcg aagtttactc aggtgcagaa ctaatgtatg
     4441 cgggcttaac tgttatctta tcccaaggag attttttgag tagacagtat atttttagaa
     4501 aactatgata tgtactgacc ccaaaagtta gatttattct gtctaacttt tggggtgcag
     4561 ttcaataagg gtgtataaat ttataaagga ggctttctaa tggaatggta taaaaaaatc
     4621 ggacttcttg caactacagg tttagctttg tttgggctcg gcgcttgctc caactatggt
     4681 aaatctgcgg atggcacagt gaccatcgag tatttcaacc agaaaaaaga aatgaccaaa
     4741 accttggaag aaatcactcg tgattttgag aaggaaaacc ctaagatcaa ggtcaaagtc
     4801 gtcaatgtac caaatgctgg tgaagtattg aagacacgcg ttctcgcagg agatgtgcct
     4861 gatgtggtca atatttaccc acagtccatc gaactgcaag aatgggcaaa agcaggtgtt
     4921 tttgaagatt tgagcaacaa agactacctg aaacgcgtga aaaatggcta cgctgaaaaa
     4981 tatgctgtaa acgaaaaagt ttacaacgtt ccttttacag ctaatgctta tggaatttac
     5041 tacaacaaag ataaattcga agaactgggc ttgaaggttc ctgaaacctg ggatgaattt
     5101 gaacagttag tcaaagatat cgttgctaaa ggacaaacac catttggaat tgcaggtgca
     5161 gatgcttgga cactcaatgg ttacaatcaa ttagcctttg cgacagcaac aggtggagga
     5221 aaagaagcaa atcaatacct tcgttattct caaccaaatg ccattaaatt gtcggatccg
     5281 attatgaaag atgatatcaa ggtcatggac atccttcgca tcaatggctc taagcaaaag
     5341 aactgggaag gtgctggcta taccgatgtt atcggagcct tcgcacgtgg ggatgtcctc
     5401 atgacaccaa atgggtcttg ggcgatcaca gcgattaatg aacaaaaacc gaactttaag
     5461 attgggacct tcatgattcc aggaaaagaa aaaggacaaa gcttaaccgt tggtgcggga
     5521 gacttggcat ggtctatctc agccaccacc aaacatccaa aagaagccaa tgcctttgtg
     5581 gaatatatga cccgtccaga agtcatgcaa aaatactacg atgtggacgg atctccaaca
     5641 gcgatcgaag gggtcaaaca agcaggagaa gattcaccgc ttgctggtat gaccgaatat
     5701 gcctttacgg atcgtcactt ggtctggttg caacaatact ggaccagtga agcagacttc
     5761 cataccttga ccatgaacta tgtcttgacc ggtgataaac aaggcatggt caatgatttg
     5821 aatgccttct ttaacccgat gaaagcggat gtggattagg agtagagaga ctatgaaaaa
     5881 agtattacaa aaatattggg catgggcttt tgtggtcatc cccctcttgt tacaagcaat
     5941 tttcttctat gtgccgatgt ttcaaggagc cttttacagt tttaccaact ggacaggatt
     6001 gacttataac tacaaatttg ttggcttaaa caactttaag ctcctcttca tggatccaaa
     6061 attcatgaat gcgattggct ttaccgcaat cattgcgatt gccatggtgg ttggtgagat
     6121 tgcactcggg atcttcattg cgcgtgtctt gaattctaaa atcaaaggcc aaaccttctt
     6181 ccgtgcttgg ttcttcttcc cagctgtttt atctggtttg acagtggctt tgatcttcaa
     6241 gcaagtcttc aactacggtc ttccagcgat tggaaatgcc cttcatattg aatttttcca
     6301 aaccagtctt ttagggacta agtggggagc aatctttgcg gctgtctttg tccttctttg
     6361 gcaaggggtg gctatgccca tcatcatctt cctagctggt ttgcaatcta ttccaactga
     6421 gattacagag gcagcaagga ttgatggtgc gactagcaag caagttttct ggaacattga
     6481 attgccttac ttgctaccaa gtgtctctat ggtctttatc ctagccctaa aaggtgggct
     6541 gactgccttt gaccaagtct ttgccatgac cggtggtggt ccaaacaatg ccacaacctc
     6601 acttgggctc ttggtttata actatgcctt taaaaacaac caattcggtt atgccaatgc
     6661 cattgccgta atcttgttct tcttaattgt agtgatttcg atcatccaat tgagagtatc
     6721 taagaaattt gaaatttaag aggagaagca tgatgaaaca agatgaaaga aaagccctga
     6781 ttggcaaata cattctattg attctaggat cggttctgat tttagtgccg ctccttgcta
     6841 ccctctttag ttccttcaaa cccactaagg atattgtaga taatttcttt ggctttccaa
     6901 ccaacttcac atgggacaac tttagccgtc tcttagctga tgggattgga ggctattatt
     6961 ggaactctgt cgtcatcact gtcttgtctt tacttgcagt aatgatcttt atccctatgg
     7021 cagcctactc catcgctcgc aatatgagta aaagaaaagc ctttaccatc atgtataccc
     7081 tcttaatcct cggaatcttc gtacctttcc aagtcatcat gattccgatt acggttatga
     7141 tgagtaaact cggtttggct aatacctttg gtttgatctt gctctacttg acctatgcga
     7201 ttccacagac cctctttctc tatgttggct atatcaaaat ctcgattcca gaaagtctgg
     7261 atgaagcagc agagatcgat ggggctaatc aatttacaac ctatttccgc atcatcttcc
     7321 caatgatgaa accgatgcat gcgacaacca tgatcatcaa tgccctttgg ttctggaatg
     7381 acttcatgtt gccactcctt gtcttgaacc gggattccaa aatgtggact ctgcctttgt
     7441 tccaatacaa ctacgcaggc caatatttca acgactacgg accaagcttt gcctcttacg
     7501 tggtcggcat tatcagtatc accattgtct atctcttctt ccaacgccat atcatttcag
     7561 gaatgagcaa cggggcagtg aagtaatact caatgaaaat caaagagcaa actaggaagc
     7621 tagccgcagg ttgctcaaaa cactgttttg aggttgtgga tgaaactgac gaagtcagta
     7681 accataccta cggcaaggtg aagctgacgt ggtttgaaga gattttcgaa gagtataaga
     7741 agagctcatg gaatctatag tctttgacac agaggaagag tttagcttgt tgataattct
     7801 atgcagaaaa caagaaagta gtactttgtt tatcacagtc tatattagta cgagtttgat
     7861 gataaataga gatttaaaat gaattttatt tatgaagcca gatcatatga gacttggctt
     7921 caattagaaa aaggagagta atgatgccaa ttcaaaataa aaccatgttg attacctatt
     7981 ctgatagcct tggaaataat cttaaagact tatatgataa tttggaagag cattttggag
     8041 atgctattgg aggagttcac cttttaccat ttttcccatc aacaggtgat cgtggatttg
     8101 cgccagttga ctacgacgaa gtggactcag cttttggtga ttgggaggat gttaagcatt
     8161 taggtgagaa atattatctt atgtttgatt ttatgattaa tcatatttct cgtcaatcca
     8221 agtattataa ggactatcaa gaaaaacatg aagccagtga atttaaagct ctctttttaa
     8281 actgggataa gttttggcca gaaaaccgtc cgacacagtc tgatgtagat ttaatttaca
     8341 agcgtaagga tcgtgcacca aagcaagaga ttgtgtttga agatggttca gtggaacatt
     8401 tgtggaatac ctttggtgag gagcagattg atcttgatgt gaccaaagaa gtaactatgg
     8461 aatttatccg taagaccatt cagcacttgg caagtaatgg gtgtgatttg attcgtctag
     8521 atgcctttgc ttatgcagtg aagaaattgg atactaatga tttctttgtg gaaccagata
     8581 tttgggattt attggacaaa gttcgagata tcgctgctga gtatgggaca gagcttttac
     8641 ctgagattca tgaacactat tcgattcagt ttaaaatagc agaccatgat tactatgttt
     8701 atgattttgc tcttccaatg gtgacacttt atactcttta cagttccaga acagagcgtt
     8761 tggctaagtg gttaaagatg agcccgatga agcaatttac gacgctagat acccatgatg
     8821 ggattggagt agtagatgtc aaggatatcc tgaccgatga ggagattgac tatgcttcaa
     8881 atgaactcta taaggttgga gccaatgtca aacgtaagta ctctagtgcc gagtataaca
     8941 acttagatat ctaccaaatc aattcaacct actattcagc gcttggagat gatgatgtca
     9001 agtattttct cgctcgtcta attcaagctt ttgccccagg tattcctcag gtttactatg
     9061 tgggtctatt agcaggcaag aatgacttga aattattaga agaaactaaa gaaggtcgaa
     9121 atattaatcg tcattactat agcaacgagg aaatagcaaa agaagtgcaa cgacctgttg
     9181 tgaaggccct tctcaatcta ttttctttcc gtaaccgttc agaagccttt gatctagaag
     9241 ggactactga gatagagaca ccaacagctc acagcattgt aatcaaacgt caaaataaag
     9301 ataagtccgt aacagcagta gcagaaattg atttgcaaaa tcagacttat cgggtaattg
     9361 agaatggagt tgaagtaaca ttttgaagcc ttgatatggt ggataaaata gggtttttat
     9421 tttggaaaac gtttcctttg ttttcaaatt gctaaaaaag tggtacaata taggacagct
     9481 tactattatc tgaatcagct gatttggaga gaaaggattc attttgaaat caataggctt
     9541 tattgaaaag ctgaaggggt tgtctagtaa agagctgatt ttattgggaa ttatcctaag
     9601 tatcttttta cccttttatc tttttgtagt tgtactctgt ttatatatta tcagtttgat
     9661 ttttacagga gacatgaaaa gtattcttca gaaaatgggg gagcatccga tgctgcttct
     9721 ttttcttagc tatagtactg ttatatccat tcttgcacaa aattggatgg gtcttgtggc
     9781 ttcagtagga atgtttctat ttactatttt ctttttgcac tatcagtcga ttttatccca
     9841 taaattcttt cgattgattt tgcagttcgt cttgtttggt agtgtcttgt cagctgcttt
     9901 tgccagttta gaacatttcc aaattgtgaa gaaatttaac tatgcttttc tttcacccaa
     9961 tatgcaggtg tggcatcaga accgggcaga agtgaccttc tttaatccta attattatgg
    10021 aattatttgt tgtttctgta ttatgattgc tttctatctg tttacaacga ccaagttgaa
    10081 ttggttgaaa gtattctgtg tgattgcagg ctttgttaat ctctttggtt tgaactttac
    10141 tcaaaatcga actgcctttc ctgctattat cgctggagca attatctatc tctttacgac
    10201 tattaaaaac tggaaggcct tttggcttag tattggggtc ttcgcgattg gtttgagttt
    10261 cctcttttct agtgatttgg gagttcgaat gggtacttta gactcttcta tggaagaacg
    10321 catttctatc tgggatgctg ggatggcctt gtttaagcaa aatccttttt ggggtgaagg
    10381 gccattgacc tatatgcact cttatcctcg gatacatgct ccttatcatg aacatgccca
    10441 cagtctttat attgatacga ttctgagtta cggaattgtg ggtaccattt tattagtttt
    10501 gtcttctgtt gctcctgttc gcttgatgat ggatatgagt caggagtcgg ggaaacgtcc
    10561 gattatcggc ctttatctat ctttccttac agtggttgct gtgcacggaa tttttgactt
    10621 ggctctcttc tggattcagt caggctttat tttcttgcta gttatgtgca gtattccatt
    10681 ggagcatcga atgttggtat cggacatgac ggattaagtt ttataagttt gaaatcttct
    10741 accttgggta ggagattttt ttatacgatg ggcatgtcgt gcatctgagg tgtaagtcct
    10801 ctgtagggat ccactaccgg tgaatacaat agcgctcccc aagcctgact atcgtgaggt
    10861 agcggattaa aatggtctgg ggatagatcg ttttaagtct gacgcaggaa ataagaattg
    10921 tcagagaaag caatagtgaa atcgtaggct atgaatagaa acgtgatagc gaggagcata
    10981 tagtggataa ggtagcgaga aattttaaag tataaaagat agtcttaatc tatatatgta
    11041 aatcacaaaa gtaattgaat tcggaataag gttggtgtga aaagacatag taaactgaat
    11101 cttgaatact agaatgatac ttctacaata ttgttataat ttaatttgaa ttccaaaatc
    11161 acattgtttc gtccgtattt cattttactg tatgtcttcc taaactccaa agtttctgcg
    11221 tcaaatttcc tattttcact gtagtctttg acacttcgaa cgacaatttg aatcatatat
    11281 tcaaaaaaaa atgaaaaatt tgtgccaaca agcctaaata ttctgaaaat ttgtttgatt
    11341 tttaatggat aatgtgatat aatggttgtc aatctataat tcacataaac agaggagtag
    11401 aaaatgaaaa aaaatcgtgt atttgctaca gcaggtcttg ttttattagc agcaggtgta
    11461 cttgcagcat gcagttcttc aaaatcatct gattcatcag cccctaaagc ttatggctat
    11521 gtttatacag cagacccaga aaccttggac tacctgattt caagtaaaaa tagtacaaca
    11581 gtagtgactt caaatgggat tgatggttta ttcactaacg ataattacgg taatcttgct
    11641 cctgcagttg cagaggattg ggaagtctct aaggatggtt tgacctacac ttataagatt
    11701 cgtaaagggg ttaaatggtt tacctctgat ggagaagaat atgcagaggt gacggctaaa
    11761 gatttcgtga acggtttaaa acacgcagca gataaaaaat cagaagctat gtatttagct
    11821 gaaaattcgg ttaaaggctt ggcagattat ctatcaggaa cttcaacaga tttttcaaca
    11881 gttggtgtca aggcggttga tgattatacg ttacaataca ctttgaacca gcctgaaccg
    11941 ttctggaact ctaagttgac ctattctatt ttctggcctc tgaatgaaga attcgaaaca
    12001 tcaaaaggaa gcgattttgc taaaccaaca gatccgacat ccttgcttta taatggtcca
    12061 ttcttgttga aagggttgac tgcaaaatct tctgtagagt ttgtaaaaaa tgagcaatat
    12121 tgggataaag aaaatgtcca cctagatact atcaatctag cttactatga tggatcagat
    12181 caggagtcgc tagagcgtaa cttcactagt ggagcttata gttatgcccg tctttaccct
    12241 accagctcca actattctaa ggttgcagaa gaatacaagg acaatatcta ttacacacaa
    12301 tcaggctctg ggattgctgg tctgggtgtg aatattgatc gccaaagtta caactatact
    12361 tctaaaacta cagattcaga gaaagtagct actaagaagg cattgcttaa caaagatttc
    12421 cgtcaagcct tgaattttgc tcttgatcgc tcagcttact cagctcaaat caatggtaaa
    12481 gatggagcag ctttagcagt tcgtaattta tttgtaaaac cagactttgt ttcagctggt
    12541 gagaagacct ttggtgattt agtcgctgct caacttcctg cttatggtga tgagtggaaa
    12601 ggtgtgaatt tagctgatgg gcaggatggt ttattcaatg ctgacaaggc caaggcagag
    12661 tttgcgaaag ctaagaaagc tttagaagca gacggcgttc agtttcctat tcatctggac
    12721 gttccagtag accaagcatc aaaaaactac atatctcgta ttcagtcctt taaacaatct
    12781 gtagaaacag ttcttggtgt tgaaaatgtc gttgttgata ttcaacaaat gacaagtgat
    12841 gaattcctta atattactta ctatgctgcc aatgcttcat ctgaggattg ggatgtatca
    12901 ggaggagttt catgggggcc agactatcaa gacccatcta cttacctgga tattttaaaa
    12961 acaactagca gtgaaactac aaaaacatat ttaggatttg ataatccaaa tagcccttca
    13021 gtagttgaag ttggtttgaa agaatacgat aaattagttg atgaagctgc cagagagaca
    13081 agcgacttga atgtccgtta tgaaaaatat gcagcggctc aagcatggtt gacagatagt
    13141 tcactcttta ttcctgctat ggcttcttct ggtgcagcac cagtgctttc acgaattgtt
    13201 ccatttactg gagcttctgc gcaaacaggc tctaaggggt cagatgttta cttcaaatat
    13261 ttgaaattac aagataaagt ggtgactaag gaagagtatg aaaaagctcg tgaaaaatgg
    13321 ttgaaagaaa aagctgaatc aaatgagaaa gctcaaaaag aattggcaag tcatgtgaag
    13381 taaataattt ctaatagaac tttctctcca tgaggagaag gttcttttgg gatttttaaa
    13441 ggaaataata tgaaaaaata tatttttatg cgtgttttgc ggtcattggt ttcgattttc
    13501 ttagtaacga ctttgaccta cacgattatc tataccttgg ttcctcgaaa attgattttc
    13561 aagcaggatc ctaactataa taaaattgcg acaacggctg ataaacgtga taactatgaa
    13621 aatactgtgt ttgagcgtat gggctacatt gagtattacg atactaaaga gttgcaagaa
    13681 aaggcaagta gcatggattc ttctgtaaca gtagaagcaa atgcgaccaa taaagctatt
    13741 tatgaaaagt acatcaatca attaggtcat ggttggactt tgggagaatt tactgaaagt
    13801 ggtcaattct atgctactcg tgaaattcca atttttgaac gtgtttttca cttctatgct
    13861 aacttgattg acattgacca tacaaataaa atccaagacc ctgaaaatcc agacttgaaa
    13921 cgctaccttc gttttgaaaa tgatccagct atcggatggt cattggtcgg ttcaggaact
    13981 aaacataaat atctcttgta ctttaacagt cagttcccat ttgttcatca aaactttgtg
    14041 aacttgaatt taggtgactc ttacccaacc tatgctaata caccagttct tcaggttatt
    14101 actcaaggtc aaggacaaac caaaactgcc caagttcagt tcccaacagg taagaaaacg
    14161 tcttctgtaa atatttactc aagaacctac aagtcaccta gtcaggctga ctctcgtgaa
    14221 gtagctagct atgggaaaga tgatccttat acagcgactg aaagtaatta ccaatatcca
    14281 tctatgattg tcagctctgc tattactggt ttgattggtt tggttcttgc ctatgctctt
    14341 gccgtgccac ttggttcagc catggctcgt ttcaagaaca cttggattga tagcctctca
    14401 acaggggctt tgaccttctt gcttgctctt ccaacgattg ccttggttta catcgttcga
    14461 ttgattggat catctattgc ccttccagat tcattcccta tcttgggagc tggagattgg
    14521 cgttcttacg ttttaccagc agtcatcctt ggtttgttgg gtgctcctgg tacagccatt
    14581 tggattcgtc gttacatgat tgacttgcaa tctcaagact ttgttcgttt cgctcgtgca
    14641 aaaggtttgt ctgaaaaaga aatttcaaac aaacacatct ttaaaaatgc catggttccg
    14701 ctggtttcag gaattcctgg tgccattatt ggggttatcg gtggtgcaac ccttactgaa
    14761 acagtcttcg ccttcccagg tatgggtaaa atgttgattg actctgtaaa agcatctaat
    14821 aactctatgg tcgttggtct tgtcttcatc tttacatgta tttctatctt ctcacgtctt
    14881 ttgggagata tttggatgac tattattgac ccacgtatta aattgactga gaaaggaggc
    14941 aaataatgtc tacaatcgat aaagaaaaat ttcagtttgt aaaacgtgac gattttgcct
    15001 ctgaaactat tgatgcgcca gcatattctt actggaaatc agtgtttaaa caatttatga
    15061 agaaaaaatc aactgtagtc atgttgggaa tcttggtagc catcattttg ataagtttca
    15121 tctacccaat gttttctaag tttgatttca atgatgtcag caaggtaaac gactttagtg
    15181 ttcgttatat caagccaaat gcggagcatt ggttcggtac tgacagtaac ggtaaatcgc
    15241 tctttgacgg tgtctggttc ggagctcgta actccatcct catttctgtg attgcgacag
    15301 tgattaactt ggttatcggt gtttttgtcg gtggtatttg gggtatttca aaatcagttg
    15361 accgtgtcat gatggaagtt tacaacgtca tctcaaacat cccacctctt ttgattgtta
    15421 ttgtcttgac ttactcaatc ggagctggat tctggaatct gatttttgcc atgagcgtaa
    15481 caacatggat tggtattgcc ttcatgatcc gtgtgcaaat cttgcgctat cgtgacttgg
    15541 aatacaactt ggcgtcacgt actttgggaa caccaacctt gaagattgtt gccaaaaata
    15601 tcatgcctca attggtatct gttattgtga caaccatgac tcaaatgctt ccaagcttta
    15661 tctcatacga agccttcttg tctttcttcg gtcttggatt accgattaca gtgccaagtt
    15721 tgggtcgttt gatttcggat tattcacaaa acgtaacaac caatgcttac ttgttctgga
    15781 ttccattgac aacccttgtc ttggtatcct tgtccctttt cgtagttggt caaaacttag
    15841 cggatgctag tgatccacgt acacatagat aggagtagaa atgacaaaag aaaaaaatgt
    15901 aattttgact gctcgcgata ttgtcgtgga atttgacgtt cgtgacaaag tattgacagc
    15961 cattcgcggc gtttcccttg aactagtcga aggagaagta ttagccttgg taggtgagtc
    16021 aggatcaggt aaatctgttt tgacaaagac cttcacaggt atgctcgaag aaaatggtcg
    16081 cattgcccaa ggtagtattg actaccgtgg tcaggacttg acagctttat cttctcacaa
    16141 ggattgggaa caaattcgtg gtgctaagat tgcgactatc ttccaggacc caatgactag
    16201 tttggacccc attaaaacaa ttggtagtca gattacagaa gttattgtaa aacaccaagg
    16261 aaaaacagct aaagaagcga aagaattggc cattgactac atgaataagg ttggcattcc
    16321 agacgcagat agacgtttta atgaataccc attccaatat tctggaggaa tgcgtcaacg
    16381 tatcgttatt gcgattgccc ttgcctgccg acctgatgtc ttgatctgtg atgagccaac
    16441 aactgccttg gatgtaacta ttcaagctca gattattgat ttgctaaaat ctttacaaaa
    16501 cgagtatcat ttcacaacaa tctttattac ccacgacctt ggtgtggtgg caagtattgc
    16561 ggataaggta gcggttatgt atgcaggaga aatcgttgag tatggaacgg ttgaggaagt
    16621 cttctatgac cctcgccatc catatacatg gagtctcttg tctagcttgc ctcagcttgc
    16681 tgatgataaa ggggatcttt actcaatccc aggaacacct ccgtcacttt atactgacct
    16741 gaaaggggat gcttttgcct tgcgttctga ctacgcaatg cagattgact tcgaacaaaa
    16801 agctcctcaa ttctcagtat cagagacaca ttgggctaaa acttggcttc ttcatgagga
    16861 tgctccaaaa gtagaaaaac cagctgtgat tgcaaatctc catgataaga tccgtgaaaa
    16921 aatgggattt gcccatctgg ctgactagga ggaaggaaat gtctgaaaaa ttagtagaaa
    16981 tcaaagattt agaaatttcc ttcggtgaag gaagtaagaa gtttgtcgcg gttaaaaatg
    17041 ctaacttctt tatcaacaag ggagaaactt tctcgcttgt aggtgagtcc ggtagtggga
    17101 aaacaactat tggtcgtgct atcatcggtc taaatgatac aagtaatgga gatatcattt
    17161 ttgatggtca aaagattaat ggtaagaaat cgcgtgaaca agctgcggaa ttgattcgtc
    17221 gaatccagat gattttccaa gaccctgccg caagtttgaa tgaacgtgcg actgttgatt
    17281 atattatttc tgaaggtctt tacaatcacc gtttatttaa ggatgaagaa gaacgtaaag
    17341 agaaagttca aagtattatc cgtgaagtag gtcttcttgc tgagcacttg actcgttacc
    17401 ctcatgaatt ctcaggcggt caacgtcaac gtatcggtat tgcccgtgcc ttggtcatgc
    17461 aaccagactt tgttattgca gatgagccaa tttcagcctt ggacgtttct gtacgtgccc
    17521 aagtcttgaa cttgctcaaa aaattccaaa aagagctcgg cttgacctat ctcttcatcg
    17581 ctcatgactt gtcggttgtt cgctttattt cagatcgtat cgcagttatt tacaagggtg
    17641 ttattgtaga ggttgcagaa acagaagaat tgtttaacaa tccaattcac ccatatactc
    17701 aagccttgct ttcagcagta ccaatcccag atccaatctt ggaacgtaag aaggtcttga
    17761 aggtttacga cccaagtcaa cacgactatg agactgataa gccatctatg gtagaaatcc
    17821 gtccaggtca ctatgtttgg gcgaaccaag ccgaattggc acgttatcaa aaaggactaa
    17881 actaataatg gttttataat ttccatgtca atttttatgg gaattataaa actttttttg
    17941 ttggactgat ttgaaaaact ttgaaagctt cctgaaagaa ttttcgaaaa attttaaaaa
    18001 attttgaaat attattgaca ggtgatgaaa aaggtggtag gataggaagg atcaaaaaag
    18061 aaagcagaaa aagaaatgaa taagagacaa gccgtaacta tgaatcaaaa cttttacttt
    18121 agctacttta gatagtgttt gtagacatgt caccatggat gcaaacagtt caagcaattt
    18181 gtttgtatct atgtggctaa gatttttgat tgtggtccat atagatgaat atctaaatgg
    18241 actagctaag ttgtaacttg ttaggttatt tcaagtaccc gtttagatag tatctaggcg
    18301 gttttttgtt ttatcttttc tgagaaggag tttcattatg aaagttgttc gaaaatcact
    18361 agccccctct tggtagtggg gatcctcttg acttctctga tcagtttgca tcagttgaag
    18421 gcagataaga aaagagatgt ctttcgtatc ggtatttcgc agtttattac ccaccagtcc
    18481 ttagacgcta ctagagaagg atttgtggat gagctggcca aacaaggcta tgttgagggg
    18541 gaaaatattg agattgattt gcaaaatgca cagggagaac aaagaaatct aaaaacgatt
    18601 tcccagcaac tagcagaatc cagcgatgtc gttctagcca tcgcaaggcc ttctgctcag
    18661 agcttggcca atacgacgca aacgccacca gttatctttt cagctgtaac agacccagtc
    18721 agtgccaagt tggttgagtc aagagaacat cctgggggca atgtaactgg gacaagcgat
    18781 cagtcatcag atgccatttc aacccaaatc aatttgataa agaaagtgtt gccaaaggct
    18841 aaaacgattg gaatcctcta tactcagagc gagcccaatt cggttgttta aaatgatgaa
    18901 gctaagcgac ttctgaaaga aaaaggcttt accgttgttg aaaaaacaat cttggacagt
    18961 aataacgtca aggcggcagc agagagtttg atggcagagg tggatatggt ttttgtccca
    19021 actgataata tcatttcgtc aaccatggaa acagttaagc aggtttctat taaacacaag
    19081 gttccagtat tcggtggttc aacagaaatg attgctgttg gtgacttgta taactacgga
    19141 accaattatg aagaattggg aagacagaca gctcgcatgc tgattcgtgt tttaaaaggt
    19201 gagaaaccag aaaatatagc agttgagttg cctgaaaaac tggaattgca taccaatcaa
    19261 gaaatggcag atgcattggg aattgatatt agtaagttag aaggcaagga ataaggagga
    19321 ttaagatgaa ttttgtgtta tctagtttat cagaaggttt gttgtggtcg attgtggcga
    19381 ttggggtcta cttgactttc cgtattttgg atattgcgga tataactgct gagggagcct
    19441 ttcctctggg ggcagcagtc gttgtatcac agatacaggc aggggcaaat ccttggcttg
    19501 cgactttact tgctttgctg gcaggtatgg tagcaggtct tgtatcagga atgctccaca
    19561 ccaagatgaa aatcccagct ctcttgacag ggattgtgac cttgacaggg ctctattcaa
    19621 tcaatattaa aattatgggc agtgtaccca atctttcctt gggagattct gcaaccgtct
    19681 ttaaacagtt ggcgagcttg ggtctgacaa atgaaggagc tgttttctca cttagtttag
    19741 tctgtctctt acttgtttgg tcttgaccct tttgatgaaa acagagattg gtttggtctt
    19801 gcgttcgact ggggataata tcccgataag tgaggccaat ggagtcaatg tagacaccat
    19861 gaagattgtt ggttacatga tttcaaacgg tttgattgcc ctatgtggtt ccttgtttgc
    19921 ccaaaatgat ggattttcag atgtgacttc tgggacagga accattgttg ttggtttgag
    19981 ctcggaagtc ttgatacacg acttgaccat tggaggccgc ttattatcca tcggaatcgg
    20041 tgctattgtt taccgtttga ttattttaaa tatctatgaa attccaaatc tagatcaaaa
    20101 cttggtacgt ctctttaatg caatcttgct cgctttggtt ttatttgcac cagaattgca
    20161 aaagagatta aagattcgtg gtctgaaatt gagaaatgaa taggaggaga aagttatggc
    20221 aagtttgtta acacttgaaa atattcacaa gacatttgaa gcagggacgg tcaatgagaa
    20281 ccatgtcctc aaaggattag atttagaggt tgaagaggga gattttatct atgtgattgg
    20341 tggaaatgga gcaggaaaat ccactttgat gaatatcttg gctggcaatc tatcggtgga
    20401 cgaaggggac cttctactgg cagggaaatc cattaaaaat ctgagtgtca gaaagagagc
    20461 caaggatatt gcccgtgttt ttcaatatcc taagatggga acagcttctc gtttgacgat
    20521 tgaggagaat atggctattg ccttgagacg tgggcaaaag agagggcttg gttggggtgt
    20581 gaaggagaag gatagaatcc agttccaaga ggccttgaag gagttgaata ttggtcttga
    20641 aaaccgctta aaagtagata ctcaatatct ctcaggagga caaagacagg ctttgaccct
    20701 agtcatggca gctctggtga aacccaaact tttacttttg gatgaacata ctgcggcact
    20761 tgacccgaaa accagtcaaa tggtgatgga cttgacgcaa aagattgtgg agcaccatca
    20821 gtggacgact ttgatgatta cccatgatat gaatcatgcg attgagtacg gcaatcgtct
    20881 cattatgctc tatcaaggca agatagtggt ggatgtcaag ggagaagaga aaaagcatct
    20941 gacagttgaa gaccttatgc atctcttcca gaaaaatagt ggccaaagtc tggtcagtga
    21001 tgaattagtt ttgggataaa gaaaaaggct gagatctggt gtctcagtct tttatttctt
    21061 gcgttttgca aaatctacaa atctaaattt ttctaactta tggcgacttt cggtaaactg
    21121 aaattggcgt ccgtcttgga gatagacttt tgatttaatc gaaacgacat aagggtcttt
    21181 gccaatgtcc atgagaatct tgtctcggtc gcttgagtgg tcaatggtga tttccttctg
    21241 agcataatca ataaggagtt tgaggccatt ttctatataa gaatagatag actgctcagc
    21301 aatttggcga gtgagatttg gaattagttc catatccaga tagtctgtat ccagaacgga
    21361 taccagatca tccaccacac gctggcggac caccttccaa accatccgaa actctgggaa
    21421 accggttatc agtgaggatt ttttatcaat aataatcttg tccagactga ccacgttggt
    21481 tttagagcgc agtccaagtt ctttaactag ttcttggtag ctggttaggt tggatacagg
    21541 gaaattgacg gtttcttctt tgacgacttg agaaccttgc cctcttatct ttttgatcaa
    21601 tccttcctct tggaggagag acagggcctt tcggacggta tcacgactca cttgatattg
    21661 ctccataagg tcgtgctcgc taggaaggaa atctccgaca gcgtaagtct cgttttgaat
    21721 ggtttcttgg atttgcttaa ataattgttg gtatttcttc attttgcctg cttaaatagg
    21781 tttttagtct agtttaatga acacctgtat ctattttacc atacaagtgc tagaaaattt
    21841 acaaaaaaac acccttttta taccaaacaa gttgcagaca agtttggtat cgtttacaat
    21901 atacttatca aatcaaactt gctttgacaa gtataaggag aatcaaatgg gaaaatttga
    21961 acaagaagcc aaagatctgc ttcaggcaat tggaggcaaa gaaaatgtga ctgccgtaac
    22021 tcactgtgcg acacggatgc gctttgtttt aggagatgat aagaaggcta atgttaaagc
    22081 tatcgagtca attccagctg ttaaaggaac ttttacaaat gcaggtcaat ttcaggtaat
    22141 cattggaaat gacgtgccca tcttttataa tgattttaca gccgtttcag gtattgaggg
    22201 tgtttccaaa gaagcagcca agtctgcagc taagagtaat caaaacgtgg tccaacgtgt
    22261 tatgaccact ctggcggaga tttttactcc gattattcca gccttgatag tcggaggatt
    22321 gatcctcggt ttccgtaatg tcttggaagg tgtccattgg tcgatgttgg atggcaagac
    22381 catcacagaa tcctctcagt tttgggcagg tgtcaatcac ttcctctggt tgcctggtga
    22441 agctatcttc cagttcttac cagtagggat tacttggtct gtttctcgta agatgggaac
    22501 cagccaaatt ttgggaattg ttctcggaat ctgtttggta tcgcctcagt tgctcaatgc
    22561 ctatgcggtt gcttcaacgc cagcagctga tatcgcggca aactgggttt ggaattttgg
    22621 ctattttact gttaatcgta tcggttacca agcccaagtt atcccagcct tgcttgcagg
    22681 tttgagtctg tcttatcttg aaatcttctg gcgcaagcat atcccagaag tcatttctat
    22741 gatttttgta cctttcttgt cattgattcc agccttgatt ttggctcata ctgttttggg
    22801 accaatcggt tggacaattg gacaagggct ttcatcagtt gtcttggcag gtttaactgg
    22861 tccagttaaa tggctcttcg gtgcaatttt tggtgccctc tacgctccat ttgtcatcac
    22921 aggtctgcac catatgacca atgccattga tacacaattg attgcggatg ctggtggcac
    22981 tgccctatgg ccaatgattg ctctttctaa tattgctcaa ggctcagccg tgtttgccta
    23041 ttatttcatg catcgccatg atgagcgtga ggctcaggtt tcacttcctg caaccatttc
    23101 agcctatctc ggtgttacag aaccagctct ttttggggtt aacgtaaaat atatttatcc
    23161 atttgttgct gggatgactg gttcagccct tgcaggcatg ttatccgtta cttttaatgt
    23221 aactgcggct tctattggta tcggtggttt gccaggtatt ctctctattc aacctcaata
    23281 catgctgcca tttgcaggaa ctatgctagt tgcgattgtt gttccaatgc tcttgacttt
    23341 cttcttccgc aaggctggtc tctttacaaa aacagagggc gatacgaact tgcaggcaga
    23401 attcgttgct caagaagaag cagaatttgt gaaccatgaa ccagtagaac ttacttcggt
    23461 agaaattatc agcccactaa ctggccaagt gaaagaattg agtcaagcga cggatcctat
    23521 ttttgcatca ggtgtcatgg ggcaaggtct agtcattgaa ccaagccaag gtgagttgac
    23581 ctctccagtt aatgggacag tgacggttct tttccctacc aagcatgcca tcggcattgt
    23641 ctctgacgag ggagttgaat tgctcatcca catcggtatg gatacagtag gtcttgatgg
    23701 caaaggtttt gaaagtcttg tagtccaagg agatcacgtt acagttggtc agcaactgat
    23761 tcgttttgat atggatgtca ttaaggctgc aggtctggtg acagaaactc ctgttatcat
    23821 caccaaccaa gatgcttata cagcgactat tcccggaact tatccgacaa cgatccaagc
    23881 tggagcatct ctcatggtcg ctacacgaat ctaatactct tcgaaaatct cttcaaacca
    23941 cgtcagctct atctgcaacc tcaaaatagt gttttgagca acctgtggct agcttcctag
    24001 tttgttcttt gattttcatt gagtataatt gaaatagcac aaatagggac ggaagactgc
    24061 ttcctccctt ttatcagaaa aggagaaaca gatgacactt gataaaggaa aagtagtcta
    24121 tcaaatctat ccaaaatctt acaaagacac cactgaaaac ggtattgggg atttccgtgg
    24181 gattatcgga aaaattccct atctagccaa actaggtgtg gatatggtct ggctcaatcc
    24241 attctatcca agtcctcaac gggataatgg ttacgatatt tcagattata tggcagtgga
    24301 tcctcttttt ggtgatatgg ctgattttga ggaaatggtg tgtatcggta aagagcacaa
    24361 gattgacttt atgctggaca tggtacttaa tcattgttcg acagagcatg aatggtttca
    24421 gaaagcccta gctggtgata agtattatca agactttttc ttcatccaag accaaccaac
    24481 agattggcag tctaagtttg gtggttctgc atgggcgcct ttcggggata ctgggaaata
    24541 ctatcttcac ctatttgatg agacccaggc tgaccttaac tggcgcaatc ccaatgtccg
    24601 taaggagctt ttcaaggttg ttaatttctg gcgcgacaag ggtgtcaaag gttttcgatt
    24661 tgatgtgatc aatttgattg gtaaggacga ggtttcagtg gactgtcctg aaaatgaagg
    24721 gaagccagct tatacagaca aacccatcgt tcataactat ttgcgtatga tgaaccaagc
    24781 cacttttgga tctgacgata gctttatgac agttggggaa atgtcttcta ccaccatgga
    24841 aaactgtgtc ctctattcgt cgcctgatcg tcaggaatta tccatgacct ttaattttca
    24901 tcacctcaag gtggactata aggatggaca aaagtggacc ttggctccct ttgattttga
    24961 agagttgaag agtctttacc atagttgggg taaggaaatg agtgataaag acggttggag
    25021 tgccctcttt tggaacaatc acgatcaacc acgtgccttg aaccgttttg tcgatattca
    25081 aaacttccgc aaggaaggag ccaccatgct agcagccagc attcacctgt cacgtgggac
    25141 accttatatc tacatgggtg aggaaatcgg gatgattgac ccagactatg attctatggc
    25201 tgattatgtg gatgtcgaat cgcttaatgc ctatcagatg ctcttagaag aaggaaagag
    25261 tcagcaagaa gccttccaga ttattcaagc taagtcgcgt gataattcac gcattcccat
    25321 gcagtgggat gcttcggaaa atgcaggatt ttcaacaggc actccttggt tgaaagctgg
    25381 taaatcctat aaatacatca atgtagaaaa tgaaatccag ggtccgattt ttaccttcta
    25441 tcaagacttg attcgactgc gtaaggaaat gccaatcatt tcagaaggaa gttacaaacc
    25501 agcctttgaa gatagcaaac aagtctacgc ttttgaacgc cagtttgagg atcaaaagtt
    25561 actagtgctc aataactttt atgctaaaga agtggaaatc gacttgccag cagtctacca
    25621 aaatggacag attttgattt caaactatga agatgcagaa gtgtctgaga aaattctact
    25681 aaaaccctat caaacactgg ctatttatgt aaattaaact tagcaaggag acctcttttt
    25741 cagaaaagca gggttctttt tgctgtctat tccatccttg aaagtgtaga acaaactggt
    25801 cagggtggct agtttgtggt ataatgaaag ggactcaaaa agaaacagga gaaaaatgat
    25861 ggatttactt ttagcaattg tattgattgt gctagctttt ctaggaggag ctcttggagg
    25921 aatgtacttg gttcgtaagc aaatcgaaaa agaatttgct gacaacccac gtttgaatgc
    25981 tgaagcagtt cgtactcttt tgagtgcaaa tggtcaaaaa ccaagcgaag ctaaggtaca
    26041 acaagtttac caccaaatca tccgccaaca aaaggcagcc cttgctaaca ataaaaagaa
    26101 aaaataaata aggaaaagtc tgggatgaaa gttccagact tctcactatg ttggttatgg
    26161 tttagggatg agactttttc cttgcattct attgatattt gattatgatt aagagagagg
    26221 tagttgacat tctatcaagc tgtcggtcag ttcgttcagt acaaggaatc ataatgaacg
    26281 atcaatcaga aaaaagacta gaaagaagac tgtatggata atcgaccaat tggttttttg
    26341 gattcgggtg tcgggggctt gaccgttgtg cgcgagctca tgcgccagct tccccatgaa
    26401 gaaatcgtct atattggaga ttcggcgcgg gcgccctatg gcccccgtcc tgctgagcaa
    26461 attcgtgaat atacttggca gctggtcaac tttctcttga ccaaggatgt caaaatgatt
    26521 gtcattgctt gtaacactgc gactgcggtc gtctgggaag aaatcaaggc tcaactagat
    26581 attcctgtct tgggtgtaat tttgccagga gcttcggcag ccatcaagtc cagtcaaggt
    26641 gggaaaatcg gagtgattgg aacgcccatg acggtacaat cagacatata ccgtcagaaa
    26701 atccatgatc tggatcccga cttacaggtg gagagcttgg cctgtcccaa gtttgctccc
    26761 ttggttgagt caggtgccct gtcaaccagt gttaccaaga aggtggtcta tgaaaccctg
    26821 cgtcccttgg ttggaaaggt ggatagcctg attttgggct gtactcatta tccactcctt
    26881 cgccctatta tccaaaatgt gatggggcca aaggttcagc tcatcgatag tggggcagag
    26941 tgcgtacggg atatctcagt cttactcaat tattttgaaa tcaatcgtgg tcgcgatgct
    27001 ggaccactcc atcaccgttt ttacacaaca gccagtagcc aaagttttgc acaaattggt
    27061 gaagaatggc tggaaaaaga gattcatgtg gagcatgtag aattatgaca aataaaattt
    27121 atgaatataa ggatgaccag gactggtatg ttgggtctta tagtattttt ggtggcgtta
    27181 acagtttgag cgactatcag acagattttc ctctgtttga attctccaaa atatttggag
    27241 atgaagagta tggtttcccg ctttcagtta ctgttttacg ctatggttct acctaccgtt
    27301 tgttctcctt tgtggtagat atgcttaatc aagaaatggg acgaaacttg gaagttattc
    27361 aacgtcatgg ggccctgctc ttggttgaaa atgggcaact cttgtatgta gaattgccta
    27421 aagaaggggt caatcttcat gatttctttg agacaagcaa ggtcagagaa accttgttga
    27481 ttgcgactcg taacgaaggc aaaaccaagg aattccgagc tatctttgat aagttaggct
    27541 acgatgtgga aaatcttaat gactaccctg acctgcctga agtagcagaa acaggtatga
    27601 cctttgaaga aaatgcccgc cttaaggcag aaaccatttc tcaattaacg ggtaagatgg
    27661 ttttggcaga tgattctggt ctcaaagtcg atgtccttgg tggcttacca ggcgtctggt
    27721 cagctcgttt cgcaggtgtg ggagcaactg accgtgaaaa taatgccaaa ctcttgcacg
    27781 aattggccat ggtctttgaa ctcaaggacc gctcggctca gttccacaca accctagtcg
    27841 tagccagccc aaataaggaa agtttagttg ttgaagcaga ctggtcaggt tatattaact
    27901 ttgaacctaa gggtgaaaat ggctttggct atgatcccct cttccttgta ggagagacag
    27961 gtgagtcatc agctgaatta accctggaag aaaaaaatag tcaatctcac cgtgccttag
    28021 ccgttaagaa acttttggag gtatttccat catggcaaag caaaccatca ttgtaatgag
    28081 cgattcccat ggcgatagct tgattgtgga agaagtccgt gatcgctatg tgggcaaagt
    28141 cgatgccgtt tttcataacg gcgattctga actacgtccg gattctccac tttgggaggg
    28201 catccgcgtt gttaaaggga acatggactt ctacgccggc tacccagaac gtctggtgac
    28261 tgagcttggt tcgaccaaga ttatccaaac tcatggtcac ttgtttgaca tcaatttcaa
    28321 ctttcaaaag ttggactact gggctcagga ggaagaggcc gctatctgcc tctatggtca
    28381 cttgcatgtg ccaagtgctt ggatggaagg caagatcctc tttctaaatc caggttctat
    28441 cagccaacca cgaggtacca tcagagaatg tctctatgct cgtgtggaga ttgatgatag
    28501 ttacttcaaa gtggactttt tgacacgaga tcacgaggtg tatccaggtt tgtccaagga
    28561 gtttagccga tgattgccaa ggagtttgag actttcttgt tggggcagga ggaaactttt
    28621 ttgacccctg ctaaaaatct agctgtgttg attgataccc acaatgcgga tcatgcgacc
    28681 ctcttgctta gtcagatgac ctatacccgt gttcccgttg tgacagatga aaaacagttt
    28741 gttgggacga ttggactcag agatattatg gcttatcaga tggagcatga cttgagccaa
    28801 gaaatcatgg cggatacgga tatcgttcat atgacaaaaa cggacgtagc ggttgtttcg
    28861 cctgatttca ccattacgga ggtcttgcac aagctagtag atgagtcctt cttaccggtt
    28921 gtggatacag agggtatttt ccaagggatt attacgcgca agtccatcct caaggccgtt
    28981 aatgccctct tgcatgattt tagtaaggaa tatgagattc gatgccaatg agagacagaa
    29041 tttcagcctt tttagaggaa aagcagggct tgtctgtcaa ttccaagcag tcctataagt
    29101 atgatttgga gcaattttta gacatggtag gtgagcggat ttctgagacc agtctcaaga
    29161 tttaccaagc ccagctagcc aatctaaaaa tcagcgccca gaagcgaaag atttcggcct
    29221 gtaaccaatt tctatacttt ctctatcaaa aaggagaggt ggacagcttt taccgcttgg
    29281 aattagccaa acaagctgaa aagaagacgg aaaagccaga gattctatac ctagactctt
    29341 tttggcagga aagcgaccat ccagagggcc gcttgctagc gctcttaatc ctagaaatgg
    29401 ggctcttgcc cagtgagatt ttagccatca aggttgcgga catcaatctg gattttcagg
    29461 tgctgcgaat cagcaaggct tcccaacaga ggattgtcac cattcccacg gccttgcttt
    29521 cagaattgga acccttgatg gggcagacct atctttttga aagaggaggg aaaccctatt
    29581 ctcgtcagtg ggcctttcgt cagttagaat cttttgtcaa ggagaaaggt tttccatcct
    29641 tatcagctca agtcttacgt gaacagttta ttctaagaca aatagaaaac aaggtcgatt
    29701 tgtacgaaat tgcaaaaaaa ttaggattaa aaacagtcct gaccttagaa aaatatagat
    29761 aatggatatt aaattaaaag attttgaagg acccctggac ttactcttgc atctggtttc
    29821 taagtaccag atggatatct acgatgtgcc cattacggaa gtcatcgaac agtatctagc
    29881 ctatgtctca accctgcagg ccatgcgtct ggaagtgacg ggtgagtaca tggtcatggc
    29941 tagtcagctc atgctgatta agagtcgtaa actccttccg aaggtagcag aagtgacaga
    30001 cttgggggat gacctggagc aggacctcct ctctcaaatc gaagaatatc gcaagttcaa
    30061 gctcttgggt gagcacttgg aagccaagca ccaagaacgg gcccagtatt attccaaagc
    30121 gccgacagag ttgatttacg aagatgcgga gcttgtgcat gacaagacga ccattgacct
    30181 ctttttggct ttttcaaata tcctagccaa gaaaaaagag gagtttgcac aaaatcacac
    30241 gacgatcttg cgggatgagt ataagattga ggacatgatg attatcgtga aagagtcctt
    30301 gattggacga gatcaattgc gcttgcagga tttgttcaag gaagcccaga atgtccaaga
    30361 ggtcatcacc ctctttttgg caaccctaga gttaatcaaa acccaggagc tgatcctcgt
    30421 gcaagaggag agttttggag atatctatct catggaaaag aaggaagaaa gtcaagtgcc
    30481 tcaaagctag acttgataga gaggaaagat gagtacttta gcaaaaatag aagcgctctt
    30541 gtttgtagcg ggtgaagatg ggattcgggt ccgccagtta gctgaactcc tctctctacc
    30601 accgacaggc atccagcaaa gtttaggaaa attagcccag aagtatgaaa aggacccaga
    30661 ttccagtttg gctttgattg agacaagtgg tgcttataga ttggtgacca agcctcaatt
    30721 tgcagagatt ttgaaggaat actctaaggc gcctatcaac cagagcttgt ctcgggctgc
    30781 ccttgagacc ttgtccatta ttgcctacaa acagccgatt acgcggatag aaattgatgc
    30841 catccgtgga gttaactcga gtggagcctt ggcaaagttg caggcttttg acctgataaa
    30901 ggaagacggg aaaaaggaag tattggggcg ccccaacctc tatgtgacta cggattattt
    30961 cctagattac atggggataa accatttaga agaattacca gtgattgatg agcttgagat
    31021 tcaagcccaa gaaagccaat tatttggtga aaggatagaa gaagatgaga atcaataagt
    31081 atattgccca cgcaggtgtg gccagtagga gaaaagcaga agagctgatt aagcaaggct
    31141 tggtgacggt taacggccaa gtggtgcgtg aactagcaac cactatcaag tcaggcgaca
    31201 aggtcgaagt tgaaggtcaa cctatctaca acgaagaaaa ggtctactat ctgcttaaca
    31261 aaccacgcgg tgtgatttcc agtgtgacag atgataaggg tcgcaagacg gttgtcgacc
    31321 tcttgcccaa tgtcaaagag cgtatttacc ctgtgggtcg tttggactgg gatacatcag
    31381 gagtcttgat tttgaccaat gatggggact ttacagacga gatgattcac cctcgtaatg
    31441 agattgacaa ggtttatgtc gcgcgtgtta aaggtgtggc caataaggac aatctccgcc
    31501 ccttgacccg tggtcttgag attgatggta agaaaaccaa gccagctgtt tatgaaattc
    31561 tcaaagtgga cccagtcaaa aatcgctctg tggtgcagtt gatcatccat gaagggcgta
    31621 accatcaggt taaaaagatg tttgaagctg ttggtctcca agtagataag ttgtctcgga
    31681 ctcgttttgg acacctagac ttgacaggac tccgtccagg agaatcccgt cgtcttaata
    31741 aaaaagaaat cagccaacta cacaccatgg ctgtaactaa gaaataatga aacgaatttt
    31801 aatagcgcct gtgcgctttt accaacgttt tatctcacca gtctttccac cctcttgtcg
    31861 ctttgagctg acttgttcca actacatgat tcaggctatt gaaaaacatg gttttaaggg
    31921 ggtattgatg ggcttgtctc ggattttacg ttgtcatccc tggtcgaaaa caggtaagga
    31981 ccccgttcca gaccgctttt cccttaaacg aaatcaagaa ggggaatgag gtggggtaaa
    32041 tagatttcaa aatgataaaa acgcatccta tcaggtttga gtgaacttga taggatgcgt
    32101 tttagaatgt caaaatttta tactcttcga aaatctcttc aaaccgcgtc agctttcatc
    32161 tgcaacctca aaacagtgtt ttgagcaacc tgcggctagt tttctagttt gctctttgat
    32221 tttcattgag tattaaattg agtttgaagt ggcttatttc aaagcttttt gtatgtcttc
    32281 aatcatgagt tttgttgatt caagtccgcc tccgcttaga taccagaggt ctggtgttag
    32341 ttggataatc ttaccatttt tagcagcagg tgtttcagcg ataagggcat tttctaggac
    32401 accgtcgttg ctagagttgt ccccaccgat ggcaagggta cggttgatga caaagaggat
    32461 gtcagggttg atttctttga cactttcaaa gctgacttct tgtccgtggc gtgagtcttc
    32521 aaatgttgta tcagttggtt tgaatttcaa ggtttggtac aagaaagaga aacgagattt
    32581 ggcaccaaag gctgccattt ttccttcatt aaggaggatc gcaagggctt ttttgtcaga
    32641 gctttcattt ttagtagcga cttcttggat gctcttgtct agcttggcca attcttcctt
    32701 ggctttctgt gtaccagttt cgccgaaggc acttgctaag gattcgatat tagccttggt
    32761 agaagtccag tagtcgtcct tgcttgcttg gaagagaacg gttggggcga tttctttgaa
    32821 tttgtctacg aatttttgtg tacgtggtga agcgataatc aaatcaggct caagggcggc
    32881 gatagcttct aaatcaggtt ctttcataga accaacattt ttgacagttc ccactaggtc
    32941 ttttagataa gtcggaacag tttttgtagg cattccgacg atattttttt caaatcctaa
    33001 agcgcgaata gtatccgcag cgccgaggtc aaaggtcaca atcttttcag gaactttgga
    33061 aagtttgacc tcgtccagtg aacttttaat ggttacctct gttggagcag agctactggt
    33121 ctctgtctga ctagtgcttg agtttgtact acatgcacca agtaggagca agaagctggc
    33181 cactagggca gtgaaataaa gtttaaggga tgttttcata atttctcctt tttaaaatgt
    33241 gataacgatt tagggagtct cttaatctta ttgactaaga gactgaaggt tctctaactt
    33301 gagcttttat gttactagct atagatacag atctttttgt tattgatatc agctagcgtg
    33361 atgggaatct cataaagttg actgagcagg tcagcctgca tgatttgatc ggttcttccc
    33421 ttgctaaaga cctggccgtc cttgaaggcg acaatttcat ctgcatactg actggccatg
    33481 ttgatatcgt ggaggacgat gataatggtc ttgccgagtt cctccaccag tcgtcgaaga
    33541 atctgcatca tgctgacgct ttgcttgata tcgagattgt tgagtggttc gtccagcaag
    33601 ataaagtccg tatcctgggc cagtaccata gcgataaaga cgcgctggag ttgcccccct
    33661 gacaggctat tgatgtagcg gtcttttaag ttggtcagtt ccaaatagtt cagagtttct
    33721 cggatttttt cccagtcttc tgatctaagt cgacctcggc tgtagggaaa acgtccaaaa
    33781 ctgaccagtt cttcaacagt caatttggct tggtaattga ttttctgttt taggatggtt
    33841 agttcttggg ccagttcttg cgaattccag ctctcgattt cacgtccttt gatactgaga
    33901 actccctgat ctttcttggt tagtctgctc atgatggaga ggagagtcga ttttccagca
    33961 ccatttggac caataaaggc tgtcagtttt tgaggactga cttcaagcga aatgccttgc
    34021 aaaatatcct gtttttgaat ggatttgtca atgttttcca gtttcactga cgagccctcc
    34081 tatatagtaa gataaagaat aagaagccac ccacactctc aatgatcata ctgatacgaa
    34141 tttccagtgc aaagactcgt tcaatcaagg cttgccccaa ggttaagcta ataaatccaa
    34201 ccagaatggc cactataaag agtaacttgt gctgatagtc tttgacaatc aggtaggtga
    34261 ggttggccag cataaagccg aagaaggcca taggtcctac caaggcagtg gccgttgagg
    34321 tcaaaagcac gattccccag aggagctctt tctgttcttt ttcaacatcg agtcccaata
    34381 tctgagccgt ttctctttgc aggtgcaaga catctagaac gactgctttt cgaaagaaaa
    34441 agattgtcaa agcgaggatg atcagagaac cgatggctag gatggaagtg ttaagatgtt
    34501 gaaaggaggc aaaaagacta ttttgcagtt tatcgtattc gtttggatcc attaggactt
    34561 gaaggaaggt gctgatattt cgaaagagac ttctgagcgc tagacagatc agcaggatga
    34621 agaccaggtc ttgcttcatc agtgtcttca agtaaccttg taaggcgaga aagaagaggg
    34681 actggacaag aagtaagact aggaattcta agatagggga tttgcccagt tgaagaaact
    34741 tgctttcaaa aaccagtagt agggtttgta gtaggacgta gaaggattca attcccaaaa
    34801 tactaggcgt caggaagcga ttttccgtca gggtttgaaa actaatggtc gaaatcccag
    34861 tcgcgatggc taccaagaga taaacgatga tcttttggga acgcaacttc caagcaaagg
    34921 ctgacaagtg agtgatgggc caaaagtaga gaagacaagc tccgatggca agaataatga
    34981 gaatccagaa gagcttggta tgtttgcttt tagtctgcat cttttcgtcc ccctctccag
    35041 agaagtagga taaagacgag actaccgatg attcctagca agagactgac agacaactca
    35101 tagggcctaa tcagaactcg ggataggata tcgcaagcca gaactagatt ggcaccaacc
    35161 agtgcgacca tgagtttggt ttgacttaga ttatctccat agcgcttgcg aacaagattg
    35221 ggaacgataa ctccgagaaa tggtaagcca cccacggtaa tcatggtgac gcttgtcgtt
    35281 agcgccacca gaaagagggc cagtttttca agtagggagt aggaaatccc caaaccctcg
    35341 ctggtttctt tccccagatt catgatggtg aaggtttggg ataatttcca aacggttatc
    35401 aggatgatga ggcctaagaa gagccactca tactgatggg tctgaatcat ggagaaggag
    35461 ccctgggtcc aggcagtcat actctgaacc agattgaaac gataggcgat aacttctgtg
    35521 actgagccga taatcccgct atagatgatc ccaatcagag gcaacatcca cctttccttt
    35581 acagtaaaaa tggtcataaa ggctaggaag aagagggtga atacgatgga tgaaacaaaa
    35641 gcgaagagca tcttttgggt cagactagcc gatggaaaga caaaaaggct cagcaccatt
    35701 cccagtttgg cggcttcagt cgttccaact gtactcggtg cagcaaactg attttgggta
    35761 atagtctgca tgagaaggcc tgccatactc atactagagg cagtcaggag aatactgata
    35821 gttcttggga gacgggactc ttgaaagagg agccaggtct gctggtcgaa atcaaatagc
    35881 tttccccatg aaaaatcact ggtcccaatg ctaatagaga gaaagactag gagtagaagt
    35941 aagccaatta aataatgaga aagtttcata ccccgtcctt tcatgtagat ttggtatcga
    36001 aagatatctg cggatataaa tgtaacatta tttttctaat ctgtcaataa aatttctgac
    36061 aatttaataa atacaacaag gagagagcaa caagactttc tcctttgtta tcctattcta
    36121 aaatgttttt accttaatct gataaaataa tatcttcgag ggagtagcta gccgtccaat
    36181 caagatattg tttagctttt gaagcatctg ctaggacact ggctgggtca ctagcacgtc
    36241 gagcaacaat ctcgtgtggg attttttaat ttagtaattc ttcagcagtt ttaaagattt
    36301 ctttgatagt atagcctttt ttagttccta agttaaagat ttgagaagaa ctgtcttctt
    36361 gaaataggta gttcattcct ttaacatgag cctatgcaag gtccaagaca taaatgtaat
    36421 ctcgaataca tgaaccgtca cgtgtatcgt agtcatctcc aaatattttt aagctatcat
    36481 gttgtcccaa tgcggtcttg ttgatatttg gaatgatgtg agttggattt ttcacacgca
    36541 gaccgtttga agcatccatt tcagccccag caacattaaa gtaacggaaa ataacatatt
    36601 tccagtcgta gcgattggcc atccagtaaa tcattcgttc gcccatcagt tttgtctctg
    36661 cataagggtt gacagggtcg agcagggtat cttcagtcac cggcttgtca atacagttat
    36721 ttccatagag agaagcagtc gaagagaaca tgattttttg aatgccaact tcagataaga
    36781 ctttgagaac ttggttcata ccagcaacgt tggcagtgaa gtatttactt ggattttcaa
    36841 tactttcgct cacaacaatt tcacctgcac aatggaggac agcatcaatc tgattttctt
    36901 ctaagtaagc ctttaaggcg ctagcatcat aaacatccag ttctttaaag ctagcacgac
    36961 tatccacagc cgctcgattt cctgtggaga gattatcgag gacatgcacc tgatagccag
    37021 catttaaaag agctttaacg gtatgggagc caatgtagct agtcccacct gtaacaagaa
    37081 ttgttttggt catgattttt tccttttcta gttttgtact atagtaaatt gaaataagat
    37141 atgaacaact ctattaggaa agtcgaatta atttctagaa atgtttcagc agctacagcg
    37201 tactattcca aactcaacca actatatatt taaagaaaga agaaagggaa gtcaactatt
    37261 ttctgtaaat ttcatgaaaa atccaaacaa ctttgatggt gtattgtttt ttttgtttgg
    37321 aaataaatat tcgagttaat tttggaatgt ttactagatt ttgcactaca tgcaagagaa
    37381 tactatcctt ttctaagata gagcaggact aagatactaa cttagaaatc caccttccca
    37441 ctatccttct cctataaaaa gtggtaaaat ggatgaaaga aagaaggaac tgaaatgaca
    37501 acattatttt caaaaattaa agaagtaaca gaacttgctg cagtctcagg tcatgaagcg
    37561 cctgtccgtg cttatcttcg tgaaaagttg acaccgcatg tggatgaagt ggtgacagat
    37621 ggcttgggtg gtatttttgg tatcaaacat tcagaagctg tggatgcacc gcgcgtcttg
    37681 gtcgcttctc atatggacga agttggtttt atggtcagcg aaatcaagcc agatggtacc
    37741 ttccgtgtcg tagaaatcgg tggctggaac cccatggtag ttagcagcca acgtttcaaa
    37801 ctcttgactc gtgatggtca tgaaattcct gtgatttcag gttctgttcc tccgcatttg
    37861 actcgtggaa aggggggacc aaccatgcca gccattgccg atatcgtttt tgatggtggt
    37921 tttgcggaca aggatgaggc agaaagtttt ggcatccgtc ctggtgatac catcgtacca
    37981 gatagttctg caattttgac agccaatgaa aaaaatatca tctcaaaagc ttgggataac
    38041 cgctacggtg tcctcatggt aagcgagcta gctgaagctt tatcaggtca aaaactcggc
    38101 aatgaactct atctgggttc taacgtccaa gaagaagttg gtctgcgtgg cgctcatacc
    38161 tctacaacca agtttgaccc agaagtcttc ctcgcagttg attgctcacc agcaggtgat
    38221 gtctacggtg gtcaaggcaa gattggagat ggaaccttga ttcgtttcta tgatccaggt
    38281 cacttgcttc tcccagggat gaaggatttt cttttgacaa cggctgaaga agctggtatc
    38341 aagtaccaat actactgtgg taaaggcgga acagatgcag gtgcagctca tctgaaaaat
    38401 ggtggtgtcc catcaacaac tatcggtgtc tgcgctcgtt atatccattc tcaccaaacc
    38461 ctctatgcaa tggatgactt cctagaagcg caagctttct tacaagcctt ggtgaagaaa
    38521 ttggatcgtt caacggttga tttgattaaa cattattaaa ccataaggga ggtggtaggg
    38581 atggcagaac caaacctaga aagccttata aaagatcttt acaatcatgc tcgacatgat
    38641 ttgagtgaag atttagttgc tgctctccta gagactgcta aaaaactgcc tactacaaat
    38701 gagcaattgc aggcagttcg tctctcaggc ctggtcaatc gtgaattgct cctaaatccc
    38761 aaacatccag cacctgagtt gctcaacttg gctcgcttta tcaaaagaga agaagccaag
    38821 tacagaggaa ctgcgacttc tgcgcttatg tatgaggaac tctttaaaat gctttgattc
    38881 cattgtggat caaagcattt tttgtaagat ctatctcgtg agcgttcaaa tagtagtaac
    38941 aaggaatcat gagaagtcag ccgagcccat agtagtgaag aaacttctgt aatggaagtg
    39001 gagcgaagtg aggaatcgtc aaacggtagg ggataggctg tttgaagggt gctacgaaaa
    39061 agatagggta aggtgaaatt atagcggaat gaaataagat atgaacaaat tgattgagga
    39121 aattaaatga atttatagaa atcttttagc agtcatggtg tcctattcca gtttcgaaat
    39181 gctataaata cgaacaaatt gattgggaaa ttcaaatcgc tttctatcaa tgttttagaa
    39241 gatacagtgc tctagtctaa cttcaatata ctataaaaga acagatggaa gcaattatga
    39301 tttacttcta tctttaaaat aaatggtctg ataggaaaaa tgtgtcccct cataaaatat
    39361 aggatagtac gaatggaagg cttttgtaga ctggaggacg aaggagttta gaaactctcg
    39421 ttaaaagtta gttgagccgg agtatggtgg tgtggataat tatcaaaaat tatttctaaa
    39481 tcgaaatagt tgacagttag aacgatgagt gttacaattg ttttattcat ttcgatatcg
    39541 aaataaattg gaggtgttat gaaagatggt catttgctag cccatcatat tcgtttgttg
    39601 aatgggcgga tttttcaaaa gttactgagt caagatcctg aggctcttta taggggtgaa
    39661 cagggcaaga ttttagcggt tttatggaat agtgaaactg gctgcgcaac tgcgacagat
    39721 atcgcgcttg cgactgggct tgcgaataat acgctaacga ctatgataaa aaagctagag
    39781 gaacaaaagc ttgtaattgt tagtccgtgt ggaaaagaca agcgtaagaa gtatttagtt
    39841 ttaacggagt taggcaagtc ccagaaagaa gtggggcatc gtgtcagtca gaaattggat
    39901 actatctttt acaaaggatt ttcagaggaa gaaattcacc aatttgaagg ttttcaagaa
    39961 agaattttgg cgaatttgaa agagaaggga aatgaggttt agaatatgtc acaacaagtg
    40021 aaaaatgctc acaacctata catccatgcc attcaagacg gacgagttgc tgaggctcaa
    40081 gcccagtctg taggggatac ctatatccaa cattcgacag gtgttcctga cgggaaagaa
    40141 ggatttgcag ccttctttgc agatttcttt gagcgtcatc cagagcgtca gattaagatt
    40201 gtccgcacca ttgaggatgg caatctggtc tttgttcatg ttcatcaata tctgaatggt
    40261 ggagaagctc aatgggtgac gacggatact ttccgtgcgg atgagaatgg tcgtattgtt
    40321 gagcattggg atgtcattga ctactatcga acacctgaaa atgatcaact agatcaaatt
    40381 tttggagatt ttgaaatcaa ggatttggac aagaaagcag aaaataaaaa actggttcgc
    40441 cgtttcttga cagaaatttt ccaaaatggg gagctagagc agtggagtga ttatgtggca
    40501 gacgatttga ttcagcataa tcatgagatt ggacaaggaa gtgctgctta taaaaactat
    40561 gtggctgaat atagtgtcac ttttgacttt gttttccaac tcttaggaca aggaaactat
    40621 gtggttagct atggtcagac tcagattgat ggcgttgctt atgcccagta cgatatcttc
    40681 cgtttagaga acgggaaaat tgtggagcat tgggataata aggaagtcat gcctaaggta
    40741 gaagacttga ctaatcgagg gaagttttaa attgaggaca aagaatgatt gaatacaaaa
    40801 atgtagcact gcgctacaca gaaaaggatg tcttgagaga tgtcaactta cagattgagg
    40861 atggggaatt tatggtttta gtagggcctt ctgggtcagg taagacgacc atgctcaaga
    40921 tgattaaccg tcttttggaa ccaactgatg gaaatattta tatggatggg aagcgcatca
    40981 aagactatga tgagcgtgaa cttcgtcttt ctactggtta tgttttacag gctattgctc
    41041 tttttccaaa tctaacagtt gcggaaaata ttgctctcat tcctgaaatg aaggggtgga
    41101 gcaaggaaga aattacgaag aaaacagaag agcttttggc taaggttggt ttaccagtag
    41161 ccgagtatgg gcatcgctta cctagtgaat tatctggtgg agaacagcaa cgggtcggta
    41221 ttgtccgagc tatgattggt cagcccaaga ttttcctcat ggatgaaccc ttttcggcct
    41281 tggatgctat ttcgagaaaa cagttgcagg ttctgacaaa agaattgcat aaagagtttg
    41341 ggatgacaac gatttttgta acccatgata cggatgaagc cttgaagttg gcggaccgta
    41401 ttgctgtctt gcaggatgga gaaattcgcc aggtagcgaa tcccgagaca attttaaaag
    41461 tgcctgcaac agactttgta gcagacttgt ttggaggtag tgttcatgac taatttaatt
    41521 gcaacttttc aggatcgttt tagtgattgg ttgacagctc tatctcaaca tttgcagttg
    41581 tcacttttga ccttgttact agctattttg cttgcgattc ccttggctgt ttttcttcgc
    41641 tatcatgaga agctggccga ctgggtcttg cagattgcag gtattttcca gaccatcccg
    41701 tctctggcct tgttggggct ctttatccct ttgatgggaa ttgggacctt gccggctttg
    41761 acagctctag tgatttatgc gatttttccg attttacaaa atactattac tgggctgaag
    41821 ggaattgatc cgagtcttca agaggctggg attgcctttg ggatgaccag atgggagcgt
    41881 ctcaagaagt ttgaaattcc acttgccatg cctgttatca tgtctggaat tcggacggca
    41941 gcggtcttga ttatcggtac ggctaccttg gcgaccttga ttggggcagg gggactgggt
    42001 tcctttatcc tgttgggaat tgaccgtaat aatgccagtt tgattttgat tggggccctt
    42061 tcttctgcag tgctagctat tgcctttaac ttcctactaa aagtaatgga aaaagcgaaa
    42121 ttgcggacga ttttctctgg ttttgccttg gtggctttat tactgggtct gtcttatagt
    42181 ccagcccttt tggctcaaaa agagaaggaa aacttgatta ttgctgggaa aataggccca
    42241 gaaccagaaa ttttggctaa tatgtataaa ttgctgattg aagaaaatac cagcatgact
    42301 gcgactgtta aaccgaattt tgggacgaca agtttccttt atgaagctct gaaaaaaggt
    42361 gatattgaca tttatcctga atttaccggt acggtgactg aaagtttgct tcaaccatca
    42421 cccaaggtga gtcatgagcc agagcaggtt tatcaagtgg cgcgtgatgg cattgccaag
    42481 caggatcatc tagcctatct caaacctatg tcttatcaaa atacctatgc tgtagctgtt
    42541 ccgaaaaaga ttgctcaaga atatggcttg aagaccattt cggatttgaa aaaagtggaa
    42601 gggcagctga aggcaggctt tacgcttgag tttaacgacc gtgaagatgg aaataagggc
    42661 ttgcaatcaa tgtatggtct caatctcaat gtggcgacta tgcagccagc tcttcgttat
    42721 caggcaattc agtcagggga tattcaaatc acggatgcct attcgactga tgcggaattg
    42781 gagcgttatg atttacaggt cttggaagat gacaagcaac tcttcccacc ttatcaaggg
    42841 gctccactca tgaaagaagc tcttctcaag aaacacccag agttggaaag agttcttaat
    42901 acattggctg gtaagattac agaaagccag atgagccagc tcaactacca agtcggtgtt
    42961 gaaggcaagt cagcaaagca agtagccaag gagtttctcc aagaacaagg tttgttgaag
    43021 aaatgatggg acagagactt
//
LOCUS       DAVBNZ010000012        40539 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000012 DAVBNZ010000000
VERSION     DAVBNZ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40539
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.012"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            3..75
                     /locus_tag="VQ860_000675"
     tRNA            3..75
                     /locus_tag="VQ860_000675"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36..38,aa:Val,seq:tac)
     gene            81..151
                     /locus_tag="VQ860_000676"
     tRNA            81..151
                     /locus_tag="VQ860_000676"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:113..115,aa:Gly,seq:tcc)
     gene            186..259
                     /locus_tag="VQ860_000677"
     tRNA            186..259
                     /locus_tag="VQ860_000677"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:Ile,seq:gat)
     gene            342..431
                     /locus_tag="VQ860_000678"
     tRNA            342..431
                     /locus_tag="VQ860_000678"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:378..380,aa:Ser,seq:tga)
     gene            445..518
                     /locus_tag="VQ860_000679"
     tRNA            445..518
                     /locus_tag="VQ860_000679"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:479..481,aa:Met,seq:cat)
     gene            522..594
                     /locus_tag="VQ860_000680"
     tRNA            522..594
                     /locus_tag="VQ860_000680"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:555..557,aa:Phe,seq:gaa)
     gene            607..687
                     /locus_tag="VQ860_000681"
     tRNA            607..687
                     /locus_tag="VQ860_000681"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:641..643,aa:Tyr,seq:gta)
     gene            692..762
                     /locus_tag="VQ860_000682"
     tRNA            692..762
                     /locus_tag="VQ860_000682"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:724..726,aa:Trp,seq:cca)
     gene            777..849
                     /locus_tag="VQ860_000683"
     tRNA            777..849
                     /locus_tag="VQ860_000683"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:810..812,aa:His,seq:gtg)
     gene            863..934
                     /locus_tag="VQ860_000684"
     tRNA            863..934
                     /locus_tag="VQ860_000684"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:895..897,aa:Gln,seq:ttg)
     gene            944..1027
                     /locus_tag="VQ860_000685"
     tRNA            944..1027
                     /locus_tag="VQ860_000685"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:978..980,aa:Leu,seq:caa)
     gene            1134..2411
                     /locus_tag="VQ860_000686"
     CDS             1134..2411
                     /locus_tag="VQ860_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET3119150.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2487..3971
                     /locus_tag="VQ860_000687"
     CDS             2487..3971
                     /locus_tag="VQ860_000687"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET3119151.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            4032..5312
                     /locus_tag="VQ860_000688"
     CDS             4032..5312
                     /locus_tag="VQ860_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3119152.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVAMA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5316..5936
                     /locus_tag="VQ860_000689"
     CDS             5316..5936
                     /locus_tag="VQ860_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3119153.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6102..7280
                     /locus_tag="VQ860_000690"
     CDS             6102..7280
                     /locus_tag="VQ860_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3119154.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATEATTTSSEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVTK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            7793..8131
                     /locus_tag="VQ860_000691"
     CDS             7793..8131
                     /locus_tag="VQ860_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3119155.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRNFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            8142..8510
                     /locus_tag="VQ860_000692"
     CDS             8142..8510
                     /locus_tag="VQ860_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET3119156.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            8617..9261
                     /gene="pcp"
                     /locus_tag="VQ860_000693"
     CDS             8617..9261
                     /gene="pcp"
                     /locus_tag="VQ860_000693"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3119157.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(9289..10146)
                     /locus_tag="VQ860_000694"
     CDS             complement(9289..10146)
                     /locus_tag="VQ860_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET3119158.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10276..11418
                     /gene="tgt"
                     /locus_tag="VQ860_000695"
     CDS             10276..11418
                     /gene="tgt"
                     /locus_tag="VQ860_000695"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET3119159.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11519..13336
                     /locus_tag="VQ860_000696"
     CDS             11519..13336
                     /locus_tag="VQ860_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET3119160.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13489..14640
                     /gene="nagA"
                     /locus_tag="VQ860_000697"
     CDS             13489..14640
                     /gene="nagA"
                     /locus_tag="VQ860_000697"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET3119161.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14803..15861
                     /locus_tag="VQ860_000698"
     CDS             14803..15861
                     /locus_tag="VQ860_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET3119162.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            16012..16377
                     /locus_tag="VQ860_000699"
     CDS             16012..16377
                     /locus_tag="VQ860_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET3119163.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16453..17394
                     /locus_tag="VQ860_000700"
     CDS             16453..17394
                     /locus_tag="VQ860_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET3119164.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17342..18358
                     /locus_tag="VQ860_000701"
     CDS             17342..18358
                     /locus_tag="VQ860_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET3119165.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMAGLVSVLALLALTFYKRSSKMNVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18360..18686
                     /gene="comGC"
                     /locus_tag="VQ860_000702"
     CDS             18360..18686
                     /gene="comGC"
                     /locus_tag="VQ860_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HET3119166.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNVGA
                     NRKVND"
     gene            18679..19083
                     /locus_tag="VQ860_000703"
     CDS             18679..19083
                     /locus_tag="VQ860_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET3119167.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            19088..19348
                     /locus_tag="VQ860_000704"
     CDS             19088..19348
                     /locus_tag="VQ860_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119168.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19311..19772
                     /locus_tag="VQ860_000705"
     CDS             19311..19772
                     /locus_tag="VQ860_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3119169.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19750..20163
                     /locus_tag="VQ860_000706"
     CDS             19750..20163
                     /locus_tag="VQ860_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3119170.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20300..20894
                     /locus_tag="VQ860_000707"
                     /pseudo
     CDS             20300..20894
                     /locus_tag="VQ860_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20955..21908
                     /locus_tag="VQ860_000708"
     CDS             20955..21908
                     /locus_tag="VQ860_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3119171.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKHLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21959..23149
                     /locus_tag="VQ860_000709"
     CDS             21959..23149
                     /locus_tag="VQ860_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET3119172.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23298..23669
                     /gene="rnpA"
                     /locus_tag="VQ860_000710"
     CDS             23298..23669
                     /gene="rnpA"
                     /locus_tag="VQ860_000710"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET3119173.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23644..24468
                     /locus_tag="VQ860_000711"
     CDS             23644..24468
                     /locus_tag="VQ860_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3119174.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24487..25473
                     /locus_tag="VQ860_000712"
     CDS             24487..25473
                     /locus_tag="VQ860_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET3119175.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25524..26147
                     /locus_tag="VQ860_000713"
     CDS             25524..26147
                     /locus_tag="VQ860_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET3119176.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26278..27735
                     /locus_tag="VQ860_000714"
     CDS             26278..27735
                     /locus_tag="VQ860_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3119177.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27758..28039
                     /locus_tag="VQ860_000715"
     CDS             27758..28039
                     /locus_tag="VQ860_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3119178.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            28116..28601
                     /locus_tag="VQ860_000716"
     CDS             28116..28601
                     /locus_tag="VQ860_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3119179.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28618..29283
                     /locus_tag="VQ860_000717"
     CDS             28618..29283
                     /locus_tag="VQ860_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET3119180.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29287..30150
                     /locus_tag="VQ860_000718"
     CDS             29287..30150
                     /locus_tag="VQ860_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET3119181.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            30152..30856
                     /locus_tag="VQ860_000719"
     CDS             30152..30856
                     /locus_tag="VQ860_000719"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET3119182.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            31035..32708
                     /locus_tag="VQ860_000720"
     CDS             31035..32708
                     /locus_tag="VQ860_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3119183.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32820..33911
                     /gene="ulaG"
                     /locus_tag="VQ860_000721"
     CDS             32820..33911
                     /gene="ulaG"
                     /locus_tag="VQ860_000721"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET3119184.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            34025..36001
                     /gene="tkt"
                     /locus_tag="VQ860_000722"
     CDS             34025..36001
                     /gene="tkt"
                     /locus_tag="VQ860_000722"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3119185.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            36118..36417
                     /gene="yajC"
                     /locus_tag="VQ860_000723"
     CDS             36118..36417
                     /gene="yajC"
                     /locus_tag="VQ860_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3119186.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36463..36891
                     /locus_tag="VQ860_000724"
     CDS             36463..36891
                     /locus_tag="VQ860_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET3119187.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36893..37303
                     /locus_tag="VQ860_000725"
     CDS             36893..37303
                     /locus_tag="VQ860_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119188.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37602..40253
                     /gene="adhE"
                     /locus_tag="VQ860_000726"
                     /gene_synonym="adhC"
     CDS             37602..40253
                     /gene="adhE"
                     /locus_tag="VQ860_000726"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET3119189.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12293 a         7267 c         9129 g        11850 t
ORIGIN      
        1 tagggagttt agctcagctg ggagagcatc tgccttacaa gcagagggtc agcggttcga
       61 tcccgttaac tcccatttta gcgggtgtag tttagtggta aaactacagc cttccaagct
      121 gttgtcgcga gttcgattct cgtcacccgc tttgaacttt gttctttgta ccaagttttt
      181 gacttgggcg cgtagctcag gtggttagag cgcacgcctg ataagcgtga ggtcggtggt
      241 tcgagtccac tcgtgcccat agtgtttagt ccattactag gggattggaa tattatctgt
      301 tcactaagag gacacgggct tgttcccgta taaactattt tggaggatta cccaagtccg
      361 gctgaaggga acggtcttga aaaccgtcag gcgtgtaaaa gcgtgcgtgg gttcgaatcc
      421 cacatcctcc ttttatatta ttaacgcggg atggagcagc tcggtagctc gtcgggctca
      481 taacccgaag gtcgtaggtt caaatcctgc tcccgcaata aggctcggta gctcagttgg
      541 tagagcaatg gattgaagct ccatgtgtcg gcggttcgat tccgtctcgc gccatttata
      601 tattttggaa gggtagcgaa gaggctaaac gcggcggact gtaaatccgc tccttcgggt
      661 tcgggggttc gaatccctcc ccttccattt tacgggcata gtttaaaggt agaactaagg
      721 tctccaaaac cttcagtgtg ggttcaattc ctactgcccg tgttaataga attatggcgg
      781 gtgtggtgaa gtggttaaca caccagattg tggctctggc atgcgtgggt tcgatcccca
      841 tcactcgcct attttatatt attggggtat agccaagcgg taaggcaagg gactttgact
      901 ccctcatgcg ttggttcgaa tccagctacc ccagttacta tttgccggcg tggcggaatt
      961 ggcagacgcg ctggactcaa aatccagtgt ccgcaaggac gtgccggttc gaccccggcc
     1021 gccggtatag tatagtgtta ggaacgttgt tattcttcgt tcctttttta tattattttt
     1081 ggtataatta tagttattca aattttattt agattaagaa agtgtagggt agtatgtctt
     1141 gttctatcga tttattaaaa catcggtatt tgaaaaatat taaagaaaat cctgaattgt
     1201 ttgtcggaat tgagttggag tatcctgttg caagtttaga aggggatgct acagatgttg
     1261 aagttataaa ggatctattt cattatttag tttctacttt ggatctcacc gtagcaaagg
     1321 tagatgattt tggcaatctg atccagttag tagatccgat aagtcaggat gctattttat
     1381 ttgaagtttc ctatacaacg attgagtttg catttggtaa ggctgaaacg attcaagagg
     1441 tcgaaaatcg tttcaataat tatatgaatg taattcagag aaagttagct gaatcaaatc
     1501 atgctattgt tggctgtggt atccatccca actgggataa aaatgagaat tgtccagtgg
     1561 cttatccacg ctatcagatg ttgatggatt atttgaattt gagtagaaat attattaaat
     1621 cagatttaca tcatttccct gaatatggta cttttatctg tgggagccag gttcagctgg
     1681 atatttcaaa aaccaactac ttacgggtga ttaatgcttt tactcaaatt gaagcggcta
     1741 aggcttattt atttgcaaac tctgaatttt cgggtgcgga ttgggatacg aaaatttcaa
     1801 gggatatttt ctgggaagaa tctatgcatg gtatctatcc agagaatgtt ggggtcaatg
     1861 ctagactcct taatgatgaa gctgattttt ttgactatct aaatcattct gcgattttta
     1921 ctgcggaacg tgatgggcag acctattatt tttatcctat tcaggctggg gactatttgg
     1981 ctacgtccga aatccaagca tttgctctga atggggatga ggttattatt tacccccaag
     2041 agaaggattt tgaaactcat cgtagttacc agtaccaaga tttaacgact cgaggaacag
     2101 ttgagtttcg tagtgtgtgt acacagccac ttgataggac ttttgcttct gcagcttttc
     2161 acttgggatt attggttaat ttagacaagt tagaagctta cttagaaaca gcacctttct
     2221 ttaaagtatt tggttatgat tacaagtctt taaggagaca attttctaag aaaaatctta
     2281 cagatgagga agaaactacg attattgaat tttccaaaga cttactccta ctagctgagg
     2341 agggactagt ggtgagaaat aaggaagaaa tgacctattt acagcctttg agagaagaat
     2401 tgagcctata atttctctta taaagggaga attttctgaa aaatcatgat ataatggacg
     2461 agactataga taaaggatag agagtaatga cattagttta tcaatcaacg cgtgatgcca
     2521 acaatacagt aactgccagc caagcaattt tgcaaggttt ggcgacggac ggcggtttgt
     2581 ttacaccggt tacttatcca aaggtagatt tggactttga caaattgaaa gatgcttctt
     2641 accaggaagt tgctaagcta gttttgtcag catttttaga tgactttaca gctgaggagt
     2701 tggactactg tatcaacaat gcctacgata gcaaatttga tactccagct attgcaccat
     2761 tagtgaaatt agatgggcaa tacaatttgg aacttttcca tggttcaacg attgccttta
     2821 aggatatggc cttgtctatt ttgccatact ttatgacgac tgctgctaag aaacatggtt
     2881 tggagaacaa gattgttatc ttgacagcga catctggtga cacggggaaa gctgctatgg
     2941 cggggtttgc ggatgtgcct ggtactgaga ttatcgtctt ttatccaaag ggtggtgtca
     3001 gcaaggtaca agagttgcaa atgaccactc agaatggtga caatactcat gttattgcta
     3061 ttgatggtaa ttttgacgat gcgcaaacaa atgtgaagca catgtttaac gacgtggctc
     3121 ttcgtgaaaa attgactacc aacaagttgc aattttcatc agctaactct atgaacattg
     3181 gtcgtctggt gccacaaatt gtttattatg tttatgctta cgctcaattg gttaagactg
     3241 gtgaaattgt agctggtgaa aaggttaact tcacagtacc aacaggaaac tttggaaata
     3301 tcttggctgc cttttatgcc aaacaaatcg gcctaccagt tggcaagcta atctgtgctt
     3361 caaatgacaa taatgtcttg acagacttct ttaaaacacg tgtctatgac aaaaaacgtg
     3421 agtttaaggt aacaaccagc ccatctatgg atatcttggt atcttcaaac ttggagcgct
     3481 tgattttcca tcttttggga aataatgctg aaaagacagc tgaacttatg aatgccttga
     3541 acacgcaagg acaatataag ttgacagact ttgatgcaga gattttggac ctctttgcag
     3601 ctgaatatgc gactgaggaa gaaacagcgg cagaaatcaa gcgtgtttat gagtcagatt
     3661 cttatattga ggatccacat acggcggttg cctcagcagt ttatagaaaa taccaagcgg
     3721 ttactggaga tgtaactaag acagtgattg cttcaacagc tagtccatac aagttcccag
     3781 tagttgcagt agaagctgta actggaaaag caggtttgac agactttgaa gccttggctc
     3841 aattacatga aatctcaggc gttgcagtgc caccagcagt tgatgggctt gaaatagctc
     3901 caattcgtca caagacaaca gtggcagctg ctgacatgca agcagcggtt gaggcttatt
     3961 taggacttta agacagaggg agcaaactcg gttgggaaac caactgagtt tcttttcatc
     4021 aggaggagag attgtttaag aaaaataaag acattcttaa tattgcattg ccagctatgg
     4081 gtgaaaactt tttgcagatg ctaatgggaa tggtggacag ttatttggtt gctcatttag
     4141 gattgatagc tatttcaggg gtttcagtag ctggtaatat tatcaccatt tatcaggcga
     4201 ttttcatcgc tctgggagct gctatttcca gtgttatttc aaaaagcata gggcagaaag
     4261 accagtcgaa gttggcctat catgtgactg aggcgttgaa gattacctta ctattaagtt
     4321 tccttttagg atttttgtcc atcttcgctg ggaaagagat gataggactt ttggggacgg
     4381 agagggatgt agctgagagt ggtggactgt atctatcttt ggtaggcgga tcgattgttc
     4441 tcttaggttt aatgactagt ttgggagcct tgattcgtgc aacgcataat ccacgtctgc
     4501 ctctctatgt tagtttttta tccaatgcct tgaatattct tttttcaagt ctagctattt
     4561 ttgttctgga tatggggata gctggtgttg cttgggggac aattctgtct cgtttggttg
     4621 gtcttgtgat tttgtggtca caattaaaac tgccttatgg gaagctaact tttggtttag
     4681 ataaggaact gttgaccttg gctttaccag cagctggaga gcgacttatg atgagagctg
     4741 gagatgtagt gatcattgcc ttggtcgttt cttttgggac ggaggcagtt gctgggaatg
     4801 caatcggaga agtcttgacc cagtttaact atatgcctgc ctttggtgtc gctatggcaa
     4861 cggtcatgct gttggcccga gcagttggag aggatgattg gaaaagagtt gctagtttga
     4921 gtaaacaaac cttttggctt tctctgttcc tcatgttgcc cctgtccttt agtatatatg
     4981 tcttgggtgt accattaact catctctata cgactgattc tctagcggtg gaggctagtg
     5041 ttctagtgac actgttttca ctacttggta cccctatgac gacaggaaca gtcatctata
     5101 cggcagtctg gcagggatta ggaaatgcac gcctcccttt ttatgcgaca agtataggca
     5161 tgtggtgtat ccgcattggg acaggatatc tgatggggat tgtgcttggt tggggcttgc
     5221 ctggtatttg ggcagggtct ctcttggata atggttttcg ctggttattt ctacgctatc
     5281 gttaccagcg ctatatgagc ttgaaaggat aggaaatgca aaaaacagct tttatttggg
     5341 atttagacgg gactttattg gactcttacg aagcgatttt atcagggatt gaggagactt
     5401 ttgctcagtt ttctattcct tatgataagg agaaggtgag agagtttatc ttcaagtatt
     5461 cggtgcaaaa tttgcttgtg cgggtggcag aagatagaaa tctggatgtt gaggtgctaa
     5521 atcaggtgcg tgcccagagt ctggctgaga agaatgctca ggtagttttg atgccaggtg
     5581 cgcgtgaggt gctagcttgg gcagacgaat caggaattca gcagtttata tatactcata
     5641 aggggaacaa cgcttttacc attctcaagg acttgggggt ggaatcctat tttacagaga
     5701 ttttaaccag tcagagtggc tttgtgcgga agccaagtcc agaagcggct acctatctgc
     5761 tagataagta tcagttgaat tctgataata cttattatat aggggatcgg actctggatg
     5821 tggaatttgc ccagaatagt gggattcaaa gtatcaactt tttagagtct acttatgaag
     5881 ggaatcacag gattcaagcg ttagcagata tttcccgtat ttttgagact aagtgataaa
     5941 aagattgtgt cagttttgtg acagagacct aacaaactat ttcaagtaat ctagtttgtt
     6001 acaaggaata gacagttctg ttaaataggc ccgagagggc tttttttcta cattttttgt
     6061 gttatgatag acaggtactc atttgaaagg aatttgaagg aatgaagaaa agaatgttat
     6121 tagcgtcaac agtagccttg tcatttgccc cagtattggc aactcaagca gaagaagttc
     6181 tttggactgc acgtagtgtt gagcaaatcc aaaacgattt gactaaaacg gacaacaaaa
     6241 caagttatac cgtacagtat ggtgatactt tgagcaccat tgcagaagcc ttgggtgtag
     6301 atgtcacagt gcttgcgaat ctgaacaaaa tcactaatat ggacttgatt ttcccagaaa
     6361 ctgttttgac aacgactgtc aatgaagcag aagaagtaac ggaagttgaa atccaaacac
     6421 ctcaagcaga ttctagtgaa gaagtgacaa ctgcgacagc agatttgaca accaatcaag
     6481 tgaccgttga tgatcaaact gttcaagttg cagatctttc tcaaccaatt gcagaagctc
     6541 caaaagaagt agcatcaaat tcagaagttg cagagacagt gactgctgca gaagaagtgg
     6601 cactatctac agactctact acgccagagg gacaaccagc cgaaacaact agtccagttg
     6661 aagaagtagc tcctcaggca acgactctag ctgagaagca ggaaacacaa gtgagctctc
     6721 aaaccgagtc agcagtggaa gcaactacaa tgccagtaga agaaaaagca accgaagcaa
     6781 ctacaacaag ttcagaagca aaagaagtag catcatcaaa tggagctaca gcagcagttt
     6841 ctacttatca accagaagag acgaaaataa tttcaacaac ttacgaggct ccagctgcgc
     6901 ccgattatgc tggacttgca gtaacaaaat ctgaaaatgc aggtcttcaa ccacaaacag
     6961 ctgcctttaa agaagaaatt gctaacttgt ttggcattac atcctttagt ggttatcgtc
     7021 caggagacag tggagatcac ggaaaaggtt tggctatcga ttttatggta ccagaacgtt
     7081 cagaattagg ggataagatt gcggaatatg ctattcaaaa tatggccagc cgtggcatta
     7141 gttacatcat ctggaaacaa cgtttctatg ctccattcga tagcaaatat gggccagcta
     7201 acacttggaa tccaatgcca gaccgtggta gtgtgacaga aaatcactat gaccacgttc
     7261 acgtttcaat gaatggataa acccgacttg gtaacatcat tttgacgaat gagatctagc
     7321 tttcgtgata ggaagcgatt ctcgttcgtt ttttctttgt catactcttc gaaaatctct
     7381 tcaaacaacg tcagttttat ctgaaacctc aaagctgtgc tttgagcaac ctgcgactag
     7441 cttcctagtt tgctttttga ttttcattga gtatcaattt gaatggaaaa tggaaagtta
     7501 tcatcttgta atgagttaag caacattctt gcaatctatt ttatagtaga ttgaaactag
     7561 aatagtacac aactgcttct aaaacattgt tagaaatcga tttgactgtc ctgatcgatt
     7621 tgtcctgctc ttatttcatt tcactatact ttatattata attgactggt caaatattga
     7681 taaatcaata aaaagagagg ggaagaaatg ctagagattc aagatttact gtatcaactc
     7741 cgcttgtctg agcaagtgag tacgcaattg tttgaaaaag cttgggatta gtttgacacg
     7801 gtatcagatt ttactgtttt tgctggagca ttctccttgt aaccaaatgg cggttcagga
     7861 gcgtttgaaa attgatcagg ctgctttgac acggaatttc aagattttgg aaacggaagg
     7921 tttggtggag cgtcatcgta atcctgaaaa tcagcgggaa gtattggtag aggctgcgaa
     7981 gtatgccaag gagcagttag tggtgaatcc ccctctgcag catatcaagg ttaaggaaga
     8041 gatggaaagt atcttaacag agtttgagag aacagaactc agccgtttat taaataaatt
     8101 ggttttgggt attgaaaata tagaaattta aggagaaata gatgtcaatt attacaatta
     8161 ttttaacaac gatcgttgct ttggagcatt tttacatttt ttatttggaa agtattgcca
     8221 cgcaatcaga tgcgactagt cgtgtattta atatggaaaa ggaagaattg gctcatccgt
     8281 cagtaagttc attgttcaaa aatcaaggga tttataaggc tctgctagga gtctttctct
     8341 tgtatgtcat ttatttctca cagaatttag aaattgtgac tatttttgtc ttatttgtga
     8401 ttggtgctgc gacttacggc tctttaacag cggataaaaa aattattttg aagcaaggtg
     8461 gatcagctat tttggccttg attagtattt tactctttaa atacacttga aggtcgattt
     8521 taatctcgct aatccttttt aatccagaat aagggaaata tgttatactt gtttttaaga
     8581 aaaaagtctc attgaattgg ttttgaggag ttagaaatga aagtattagt gacaggtttt
     8641 gagccctttg gaggggaaaa gggcaatcca actttggagg ccattaaagg tttaccagct
     8701 gaaatccatg gtgctgaggt ccgttggcta gaggtgccga cagtttttca caaatctgct
     8761 caagtattgg aagaagagat gaatcgttat caacctgact ttgtcctttg tattgggcaa
     8821 gctggtggaa gaactagtgt gacacctgaa cgagtggcca ttaatcaaga cgatgcacgc
     8881 atttctgata acgaagataa tcaaccgatt gaccgtccca ttcgcccaga tggtgcttcg
     8941 gcctacttta gtagtttgcc gattaaagcg atggttcaag ctataaaaaa agagggctta
     9001 ccggcctctg tttccaatac ggcagggact tttgtctgca gccatttgat gtatcaggct
     9061 ctctatttgg tagaaaagaa atttccatat gttaaggcag gttttatgca tattccttat
     9121 atgatggaac aggtggtgaa cagaccgact actccaacta tgagtttagt ggatattcgg
     9181 cgagggatag aagcagcaat cggcgctatg atagaacatg gagatcagga actcaagttg
     9241 gtaggcggag aaactcattg atagaaaaaa gcttgagggg aaaaaccttc aagcttttgg
     9301 acgttttcga gccaatactg ctcggtaaaa cataatttta gtgcattgga tataaggtag
     9361 gagtgaaaaa ctagcaatgc caaaggtaat ccaattgagg aagtaccaag gaagaagctg
     9421 taaatctagg acaaagtgct ggaacttgta gcccttcata aaggaacggc tagtttttag
     9481 gattcgtctt ggtgggacct gtcctaggtc tagactataa cagagaagaa attccacctg
     9541 tgaataggca taatactgtg gaatatagag gatatttcct acaatgatca agatgagact
     9601 tgcaagaaag tagagtccaa agaccatgag gaaacgctcg gtttcaactg atgagagatc
     9661 tagatttgga aactcaggat gtagggtgac gaattttttg gctaaaaagc tactataaaa
     9721 gaggaggtaa atcccaagta aattagggat actccataaa aagagataga aacgtttgag
     9781 aagtagggtc aaaaaggttt gagaaaagcg ctcctcatca aagagagcta ggctgttttt
     9841 tacagatggc tccgttttag aatctttcat gagtgtcagt gttgcataga cggaactggt
     9901 caaaagaata gtcccgataa aggagactag tagaggaaag aggtaggttt gaagtatttg
     9961 gccaagtatg ctgaaaaatg gctgttctaa aacagtcccg tggatccgag ataagggatt
    10021 aagaaaacca gataagatga ccagcatact gggaaggata tagaggagaa agagacgggg
    10081 ggtgtcagcc tgaaaatgtt ttgactcctg acgaattgtt tttaaatcaa tttttggata
    10141 gttcattctc ttattatacc atagttctta tacatagttc gtgacagttc ctactttttt
    10201 tgataaaatc atacagtgtg tccttgggca cactgtatga actgggactg tctttcccag
    10261 cttcggaggt aaaaaatgtc agattcacca atcaaatatc gtttgattaa gaaagaaaaa
    10321 cacacaggag ctcgtctagg agaaatcatc actccccacg gtacctttcc gacacctatg
    10381 tttatgccag ttgggacaca agccactgtc aaaactcagt cacctgaaga attgaaggag
    10441 atgggttcgg gaattatcct atcaaacacc tatcatctct ggcttcgccc tggagatgaa
    10501 ctcattgcac gcgctggtgg tctccacaag ttcatgaatt gggaccagcc tatcttgaca
    10561 gatagtggtg gttttcaggt ttattcttta gcagatagcc gtaatatcac agaagaagga
    10621 gtaaccttta aaaatcatct aaatggttct aagatgctcc tatccccaga aaaagccatc
    10681 tctattcaga ataatctggg ttcagacatc atgatgtcct ttgatgaatg tcctcagttt
    10741 tatcaacctt atgactacgt taagaaatcg atcgagcgta ccagccgttg ggctgagcgt
    10801 ggtttgaagg ctcaccgtcg tccacatgac caaggtttgt ttggaattgt gcaaggtgca
    10861 ggatttgaag accttcgccg ccaatcagct cacgatcttg tcagcatgga tttctcaggc
    10921 tactctatcg gtggtttggc agtgggagaa acccatgaag agatgaatgc ggtcttggac
    10981 tttacaactc aactgctgcc tgaaaataaa cctcgttatc tgatgggtgt gggagcgcca
    11041 gatagcttga tcgatggggt cattcgtggg gtggatatgt ttgactgtgt cttaccgact
    11101 cgaattgctc gtaacgggac ttgtatgacc agtcaaggac gtttggttgt gaaaaatgcc
    11161 cagtttgctg aggactttac gccactggat cctgagtgtg attgctacac atgtaataac
    11221 tatacacgcg cttaccttcg tcacctgctc aaggctgatg aaacctttgg tatccgcttg
    11281 actagctacc acaatcttta cttcttgctt aacctgatga agcaagtgcg acaagccatc
    11341 atggatgaca atctcttgga attccgtaag tattttgtgg aaaaatatgg ctataataag
    11401 tcaggacgta atttctaaaa tggaattgat ataagctaaa aatcctaagt tttctcttag
    11461 gatttttctt ctttttttga tagaataaag tgtacaatga aaggaagaat aaactcgtat
    11521 gcgcattaaa tggttttcct tgattaggat tataggttta cttttggtac tcttgtatca
    11581 cttctttcag acgatctttc ctggaggatt tttcggggta gatgtctttt tcacattttc
    11641 aggtttcctg attacagctc tactcattga agaattttct aagaacaatg agattgattt
    11701 gataggattt tttagaagac gcttttatcg gattgtgcca cctgtggttt tgatggtctt
    11761 ggtgaccatg ccttttactt tcttggttcg ccaagactat gttgctggaa ttggtggcca
    11821 gattgcgggc gtcttaggct ttatgaccaa cttctatgaa ctcttaacag gtgggagtta
    11881 tgaatctcag ttcattcctc atttgtttgt tcataattgg agtttggcag ttgaggttca
    11941 ctactatatt ctttggggat tggcagtttg gttcttatcc aaacaagcta aatcaaatgg
    12001 tcagttgaag gggatgatct ttctcttatc tgctactgcc ttcttgatca gtttcttctc
    12061 catgtttatt ggtagttttc tagtgacctc ttattcctct gtttatttct ccagtttaac
    12121 tcatgtctat ccattctttt tgggaagtat gttagcaact attgtaggcg ttcgtcagac
    12181 gacttccctc gtcaagcagt tggataaaat ctgggattta cgaaagactt tagtagtttt
    12241 tggaggaggc tttggtttcc tagttctttt gactttcttt gtcaaattca cttatctttt
    12301 tgcctatctt atcggcttct tgcttgccag tcttgcagct cttgccatga ttctggcggc
    12361 gcgtgtctta catgaaaaga cacatcatat acaggagccg aagattatca gctttttagc
    12421 ggatactagc tatgcggttt atcttttcca ttggcctttc tatatcattt tctcacagtt
    12481 gacatcaaat cttcttgctg tattactgac tctgatttgt tcttatggct ttgccagtct
    12541 gtcattttat gtattggaac cttggattgc aggcaagaac acacctattt tacaaactct
    12601 tcgtcccctg ccttatattc acgcaattct tgcagcaggt acaggaatct tgaccttcat
    12661 tgtctgcatg gtgaccttgt tggcaccaca agtgggagcg tttgagacag acttgactgt
    12721 caatggcttg aagcaagctg caacaaatat tggccagacc aaggtgatgg cagaacgggc
    12781 agatgcaaac agtttgggaa ttgctgatgg cactatgtta attggtgact cagtggcttt
    12841 aagggcaaat acagcactac agacagctct tcctggagca cagattaacg cgcaggtcag
    12901 cgtaacaacc aagaccgcaa atgaaatcat gctaaataat agccagaata aatttttacc
    12961 taagacggtg gtcattgcga ctggggtaaa taatcctgag aattacaagg atgactggga
    13021 cagtatcgtg aaaaatcttc ctaagggaca ccatatgatt ttggtgactc cttatgaggg
    13081 tgataagaca aaagagacct atgccatcgt tgagaaggct gctgcctata tgagagaatt
    13141 ggcagagaag acaccttaca ttacgatagc agattggaat caagttgcga aagagcatcc
    13201 agaaatttgg gctggaacag accaggttca tttcgggagt gagagtagca ctatcgaagc
    13261 aggagcaaaa ttgtatgcag atacgattgc cacagctttg cagacagctc aagacaagcc
    13321 ggttaaatca aaataacttg tattaaaaaa gagaagagtt ggagaaatcc agctctttta
    13381 aaatatctcc aaaaaatagg tctataccat ttacaaataa aaaagaaagg tttataatgt
    13441 aattgacata ataaattgta gaatcaatct tttaaggagg ttaacattat gcctaactat
    13501 attaaagcgg atcagttttt ctacccacac ggagttcgtc gaggtggtta cttggaactt
    13561 gtggacggca agtttggaaa acatgtagag cagattcctg aaggggctga ggtgattgac
    13621 tatacaggtt atagcattgc cccaggtctt gtggatactc atattcatgg atatgcaggt
    13681 gtagatgtga tggacaacaa cattgaaggt acattgcata ctatgagtga aggacttctt
    13741 agtaccggtg ttaccagttt cttacccaca actttaacag ccacttatga gcaattgctt
    13801 gcagtcactg aaaatcttgg aaaccattat aaagaagcaa caggtgctaa gattcgtggg
    13861 atttattatg aaggtccata tttcacagaa acttttaagg gggcacaaaa tccaacttat
    13921 atgagagacc cgggtgttga ggagtttcat tcttggcaaa aagcggcaaa tggcttgctt
    13981 aataaaattg cccttgcacc agaacgtgat ggggtggaag actttgttcg tacagttacg
    14041 ggcgaaggtg tgacggttgc tcttggacat tcaaacgcga cttttgatga agccaaaaaa
    14101 gcagtcgatg ctggagcgag tgtttgggtg catgcctaca atggaatgcg tgggttgact
    14161 caccgtgaat tgggtatggt tggagccatg taccaattgc cacataccta tgcagagttg
    14221 atctgtgatg gtcaccacgt agatccaaag gcttgcgaaa ttcttatcaa acaaaaagga
    14281 acagaaaaca tcgctcttat cacagactgt atgacagctg ggggattgga agacggagat
    14341 tatatgttgg gagaattccc agttgtcgtt gcaaatggaa ctgcacgcct caaatcgaca
    14401 ggtaacttgg caggttctat cctcaaactc aaagatggtt tgaagaatgt ggtcgaatgg
    14461 ggaattgcga atccgcatga agcagtcatg atggccagct tcaacccagc taaatccgtt
    14521 cacatcgatg acgtctgtgg ccaaatccgt gaaggctacg acgctgactt catcgtatta
    14581 gataaagatt tggaattggt agcaacctac ctagatggcg tgaaacgtta tcaagcataa
    14641 gagagaaggc agaagttaga gactaacttc tgctttttta tacagggtac tttactggta
    14701 aataaaaagt taaaaaaatc acaaaaaaag cttgaagaaa caaagaaaaa tgcttacaat
    14761 tgaactataa atattacaaa taaaaaaacg gaggagtgct ttatgaaagc ctatacttat
    14821 gttaaaccag gacttgcttc ttttgttgat gtagacaaac cagttattcg caagccaaca
    14881 gacgctattg tgcgtattgt aaaaaccact atttgtggaa cagacctcca tattatcaaa
    14941 ggggatgttc ctacttgcca aagtggtacc attcttggcc acgaagggat tgggattgtt
    15001 gaagaagttg gggaaggagt ttccaacttc aaaaaaggtg acaaggtctt gatttcttgc
    15061 gtctgtgcct gtggtaaatg ctactactgt aaaaaaggaa tttatgccca ctgtgaagac
    15121 gaagggggct ggattttcgg tcacttgatt gatggtatgc aggctgaata tctacgtgtc
    15181 cctcatgcag ataatactct ttaccatact ccagaagact tgtcagatga agctttggtt
    15241 atgctgtcag acattctgcc tactggatat gaaattggtg tcttaaaagg gaaagtagaa
    15301 cctggttgca gcgtagccat tattggttca ggtccagttg gattggctgc tcttttaaca
    15361 gcccaattct attcaccagc taaattgatt atggtagacc tagacgataa ccgcttggaa
    15421 actgccctat cattcggtgc gactcataag gttaattctt cagaccctaa aaaagccatt
    15481 aaagaaattt atgatttgac agatggtcgt ggtgtggatg tcgctatcga agctgtaggg
    15541 attcctgaaa catttgattt ctgtcaaaag attatcggtg tagacggaac ggttgccaac
    15601 tgtggtgtgc atggtaaacc agttgaattc gatttagata aactttggat tcgcaacatc
    15661 aatgtaacaa ctggtttggt atctacaaat acgactccac aattgttgaa agcacttgaa
    15721 agtcataaga ttgaaccgga aaaattggta actcactatt tcaaactcag tgaaattgaa
    15781 aaagcctacg aagtcttcag taaggcagca gaccaccatg ccattaaggt cattatcgaa
    15841 aacgatatct cagaagccta agtagtaaaa atatttttgt acataagcaa atagaaattc
    15901 agtcatccat cagatggctg gattttttat caaaaaatta agaaatgagc atatttcttt
    15961 ccttgtctgg cggaattggt tataatatac ggtacaaagg aatgaatgaa tatgtatcgt
    16021 gttatagaaa tgtacggaga ttttgaaccg tggtggttct tagaaggttg ggaagaagat
    16081 attgtagcaa gtagaaaatt tgaccagtat tatgatgctc tcaaatacta caaaacttgc
    16141 tggtttagat tggaacaaga atcccctctt tataaaagta gaagcgactt gatgaccatt
    16201 ttttgggacc cggaagacca acgctggtgt gatgaatgtg atgagtattt acaacaatac
    16261 cattctttgg ctcttttgca ggatgagcag gttatcccag acgaaaaact acgctcaggc
    16321 tatgaaaaac aaaccagtca ggaaaggaat cgttcttgcc gtatgaaatt aaaatagaga
    16381 aaagtaactt ttttggagtt gcttttttta tttttctaac gctttgcgaa tagtataggt
    16441 gaggaggtaa gtatggttca agaaattgca caagaaatca ttcgttcagc tcggaaaaaa
    16501 gggacgcagg atatttattt tgtccctaag ttagacgcct atgagcttca tatgagggta
    16561 ggagacgagc gctgtaaaat tggtagctat gattttgaaa agtttgcagc cgttatcagt
    16621 cactttaagt ttgtggcggg tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc
    16681 tgtgattatg cctatgacca gaagatggcg tctctacgtt tatctactgt aggcgattat
    16741 cggggacatg agagtttggt tatccgtttg ttgcacgatg aggagcagga cttgcatttt
    16801 tggtttcagg atattgaaga attaggcaag cagtacaggc aacggggact ctatcttttt
    16861 gctggcccgg ttgggagtgg taagacgacc ttgatgcatg aattgtccaa gtcactcttt
    16921 aaaggacagc aagttatgtc catcgaagat cctgtcgaaa tcaagcagga cgacatgctt
    16981 cagttgcagt tgaacgaagc aatcggccta acctatgaaa atctaatcaa actttccttg
    17041 cgtcatcgac cagatctctt gattatcgga gaaattcgtg acagcgagac ggcgcgtgca
    17101 gtggtcagag ctagtttgac aggtgcgaca gtcttttcaa ccattcacgc caagagtatc
    17161 cgaggtgttt atgagcgtct gctggagttg ggtgtgagtg aagaagaatt ggcagttgtt
    17221 ctgcaaggag tctgctacca gagattaatc gggggaggag gaatcgttga ctttgcaaac
    17281 agagattatc aagaacacca agcagccaag tggaatgagc aaattgacca gcttcttaaa
    17341 gatggacata tcacaagtct tcaggctgag acggaaaaaa ttagctacag ctaagcaaaa
    17401 aaatatcatc accctattta acaatctctt ttctagcggt tttcatctgg tggagactat
    17461 ctccttttta gataggagtg ctttgttgga caagcagtgt gtgatccaga tgcgtgtggg
    17521 cttgtctcag gggaaatcat tctcagaaat gatggaaagt ttgggatgtt caagtgctat
    17581 tgtcactcag ttatccctag ctgaagttca tggcaatctc cacctgagtt tgggaaagat
    17641 agaagaatat ctggacaatc tggccaaggt caagaaaaaa ttgattgaag tagcgaccta
    17701 tcccttgatt ttgctgtttt ttcttctctt aatcatgctg gggctacgga attacctgct
    17761 cccacaactg gatagtagca atattgccac ccgaattatc ggtaatctgc cccaaatttt
    17821 tctaggcatg gcagggcttg tttccgtgct tgccctttta gcactaactt tttataaaag
    17881 aagttctaag atgaatgtct tttctatctt agcacgcctt ccctttattg gaatctttgt
    17941 gcagacctat ttgacagcct attatgcacg tgaatggggg aatatgattt cacagggaat
    18001 ggagttgacg cagatttttc aaatgatgca ggaacaaggt tcccagctct ttaaagaaat
    18061 cggtcaagat ctggctcaaa ccctgaaaaa tggccgtgaa ttttctcaga cgataggaac
    18121 ctatcctttc tttaggaagg aattgagtct catcatagag tatggggaag ttaagtccaa
    18181 gctgggtagt gagttggaaa tctatgctga aaaaacttgg gaagcctttt ttacccgagt
    18241 caaccgcacc atgaatttgg tgcagccact ggtttttatc tttgtggcac tgattatcgt
    18301 tttactttat gcggcaatgc tcatgcccat gtatcaaaat atggaggtaa atttttaaaa
    18361 tgaaaaaaat gatgacattc ttgaaaaaag ctaaggttaa agcttttaca ttggtggaga
    18421 tgttggtggt cttgctgatt atcagcgtgc ttttcttgct ctttgtacct aatctgacca
    18481 agcaaaaaga agcagtcaat gacaaaggaa aagcagctgt tgttaaggtg gtggaaagcc
    18541 aggcagaact ttatagcttg gaaaagaatg aagatgctag cctaagcaag ttaaaagacg
    18601 atgggcgaat cacggaagaa caggttaaag cttataaaga atacaatgat aaaaatgtag
    18661 gagcaaatcg taaagtcaat gattaaggcc tttaccatgc tggaaagtct cttggttttg
    18721 ggtcttgtga gtatccttgc cttgggcttg tccggctctg ttcagtccac ttttgcggca
    18781 gtagaggaac agattttctt tatggaattt gaagaactct atcgggaaac ccaaaaacgc
    18841 agtgtagcca gtcagcaaaa gactagtctg aacttagatg ggcagacgat tagcaatggc
    18901 agtcaaaagt tgccagtccc taaaggaatt caggtcccat caggccaaag tattacattt
    18961 gaccgtgctg ggggcaattc gtccctggct aaggttgaat ttcagaccag taaaggagcg
    19021 attcgctatc aattatatct aggaaatgga aaaattaaac gcattaagga aacaaaaaat
    19081 tagggcagtg attttactgg aagcagtagt cgctctagct atctttgcca gcattgcgac
    19141 cctccttttg ggacaaattc aaaaaaatag gcaagaggaa gcaaaaatct tgcaaaagga
    19201 agaagtcttg agggtagcta agatggcctt gcagacgggg caaaatcagg taagcatcaa
    19261 cggagttgag attcaggtat tttctagtga aaaaggattg gaggtctacc atggttcaga
    19321 acagttgttg gcaatcaaag agccataagg tcaaggcttt taccttgtta gaatccctgc
    19381 ttgccctcat tgtcatcagt gggggattac tcctttttca agctatgagt cagctcctca
    19441 tttcagaagt tcgctaccag caacaaagcg agcaaaagga gtggctcttg tttgtggacc
    19501 aacttgaggt agaattagac cgttcgcagt tcgaaaaagt agaaggcaat cgcctataca
    19561 tgaagcaaga tggcaaggac atcgccatcg gtaagtcaaa gtcagacgat tttcgtaaaa
    19621 ccgatgctag tggacggggg tatcagccta tggtttatgg cctcaaatca gctcagatta
    19681 cagaggacaa tcaactggtt cattttcgtt tccagtttca aaaaggctta gaaagggagt
    19741 tcatctatcg tgtggaaaaa gaagaaagtt aaggcaggtg ttctcctcta tgcagtcacc
    19801 atggcagcta tctttagtct tttgttgcaa ttttacttga accgacaagt cgcccactat
    19861 caagactatg ctttgaataa agaaaaattg gttgcttttg ccatggctaa acgaaccaag
    19921 gataaagccg agcaagaaag tggggaacag gtctttaatc taggtcaggt aagctatcaa
    19981 aacaagaaaa caagcttggt gacgactgtt cgtacgtcta agagccaata tgagtttctg
    20041 tttccttcag tcaaaatcaa agaagagaaa agagataaaa aggaagaggt agcgaccgat
    20101 tcaagcgaaa aagtggagaa gaaaaaatca gaagagaagc ctgaaaagaa agagaattcc
    20161 tagtcaattc aactataatg cgttgaatca agaatagtcc actatagttt ctagaaaatt
    20221 gctggaaatg gatgttaagc tccaattcat ttgtttatat cttatttcag tttactatac
    20281 tttgtgctaa attaaagata tgaaacatga ttttaaccac aaagcagaaa ctttcgattc
    20341 ccctaaaaat atcttcctcg caaacttggt atgtcaagca gccgagaaac agattgatct
    20401 tctatcagac aaagaaattt tagatttcgg tggtgacacg ggtctattag ccttgcccct
    20461 agcccctagc caagcaggct aagtcagtca ctcttgtaga catttctgag aaaatgttgg
    20521 agcaagctcg tttgaaagtg gagcagcaag caatcaagaa tatccagttt ttggagcaag
    20581 atttaccgaa aaatcccttg gagaaagagt ttgattgcct tgctgttagt cgggttcttc
    20641 atcatatgcc tgatttggat gcggctctct cactgtttca tcaacatttg aagtaagatg
    20701 ggaaactcat cattgctgat tttaccaaga cagaagctaa tcatcatgga tttgatttag
    20761 ctgaactgga aaacaagcta attgagcatg gtttttcatc tgtgcatagt cagattctct
    20821 atagcgctga agacttgttt caaggaaatc actcagaatt ctttttaata gtagcccaaa
    20881 aatcactcgc ctagtcaggg agtgattttt ctataaggat ggaaaaaaga agggaaattt
    20941 gataagatag gaatatggat tttgaaaaaa ttgaacaagc ttatacctat ttactagaga
    21001 atgtccaagt catccaaagt gatttggcga ccaactttta tgacgccttg gtggagcaaa
    21061 acagcatcta tctggatggt gaaactgagc taaaccaggt caaagacaac aatcaggccc
    21121 ttaagcattt agcactacgc aaagaagaat ggctcaagac ctaccagttt ctcttgatga
    21181 aggctgggca aacagaaccc ttgcaggcca atcaccagtt tacaccggat gctattgctt
    21241 tacttttggt gtttattgtg gaagagctgt ttaaagagga ggaaattact atcctcgaaa
    21301 tgggttctgg gatgggaatt ttgggcgcta ctttcttgac ctcgcttact aaaaaggtgg
    21361 attatttggg aatggaagtg gatgatttgc tgattgattt ggcagctagc atggcagatg
    21421 taattggttt gcaggctggc tttgtccaag gagatgccgt tcgtccacaa atgctcaaag
    21481 aaagtgatgt ggtcatcagc gacttgcctg ttggctatta tcctgatgat gccgttgcgt
    21541 cgcgccatca agttgcttct agtcaagaac atacttacgc ccatcacttg ctcatggaac
    21601 aaggacttaa gtacctcaag tcagacggat acgctatttt tctagctccg agtgatttgt
    21661 tgaccagtcc tcaaagtaat ttgttgaaag tctggttgaa agaggaggca agtctggttg
    21721 ctatgattag tttacctgaa aatctctttg ctaatgctaa acaatctaag actattttta
    21781 tcctacagaa gaaaagtgaa atagcagtag agccttttgt ttatccactt gctagcttgc
    21841 aagatgcaag tgttttaatg aaatttaaag aaaattttca aaaatggact caaggtactg
    21901 aaatataaaa tagattttgt tataatagtt gaaaacgctt aaaaaggggt atcatgttat
    21961 gacaaaaaca attgcaatca atgcaggaag ttcaagtttg aaatggcaat tatacttaat
    22021 gccagaagaa aaagtattgg cgaaaggttt gattgaacgt atcggtttga aagattcaat
    22081 ttcaactgta aaatttgacg gccgttctga acaacaaatt ttggatattg aaaatcatac
    22141 acaagctgtt aaaattttat tggatgactt gattcgtttc gatattatca aggcttatga
    22201 cgagattaca ggtgttggac atcgtgttgt tgctggtgga gaatatttca aagaatcaac
    22261 agttgttgag ggagatgttt tagaaaaagt tgaagagttg agtttgttgg ctcctctaca
    22321 caacccggca aatgcagcag gtgttcgtgc cttcaaggaa ttgttgccag acattaccag
    22381 tgtagttgtt tttgatactt ccttccacac aagtatgcca gagaaagctt atcgctaccc
    22441 tctaccaaca aaatattaca cagaaaacaa ggttcgtaaa tacggtgctc atggtacaag
    22501 tcaccagttt gtagcaggag aagctgcaaa actcttggga cgtccattag aagacttgaa
    22561 gttaattacc tgtcatattg gtaacggagg ctcaattaca gctgtgaaag ccggcaaatc
    22621 tgtagacact tctatggggt tcactcctct tggtggtatt atgatgggaa cgcgtacagg
    22681 ggatattgat ccagctatca ttccttattt aatgcaatat acagaggatt ttaacacacc
    22741 agaagatatc agtcgtgttc ttaaccgtga atcaggtctt ttgggagttt ctgctaattc
    22801 tagcgatatg cgcgatatag aagcagctgt agcagaaggg aatcacgagg ctagcttggc
    22861 ttatgaaatg tatgttgacc gtatccaaaa acatatcggt cagtaccttg cagtgctaaa
    22921 tggagcagat gccattgttt tcacagcagg tgtcggtgaa aatgcagaga gtttccgtcg
    22981 tgatgtaatc tcagggattt cgtggtttgg ttgtgatgtt gatgatgaaa agaatgtctt
    23041 tggcgttaca ggagacatct caacagaggc agctaaaatc cgtgtcttgg ttattccaac
    23101 agatgaagaa ttagtcattg cccgtgacgt tgaacgcttg aaaaaataag tgaaactaaa
    23161 aaaatattca atacaaggag ttgggaaagt tatttttcca gcttcttttt ctgatgaaat
    23221 tgtccaaaac cttgctatga ttggcttttt tgaaaaatat ggtataatag tagtaattta
    23281 atagatggag ttgagttttg aagaaaaact ttcgtgtaaa aagagagaaa gattttaagg
    23341 cgattttcaa ggaggggaca agttttgcta atcgcaaatt tgtggtctac caattagaaa
    23401 accagaaaaa ccattttcga gtaggtctat cagttagcaa aaaactgggg aatgccgtca
    23461 ctagaaatca aattaagcga cggattcggc atattatcca gaatgcaaaa gggagtctgg
    23521 tagaagatgt cgactttgtt gtcattgctc gaaaaggagt cgaaaccttg ggatacgcag
    23581 agatggagaa aaatctactc catgtattaa aattatcaaa gatttaccgg gaaggaaatg
    23641 ggagtgaaaa agaaactaaa gttgactagt ttgctaggac tgtctctgtt aatcatgaca
    23701 gcctgtgcga ctaatggggt aactagcgat attacagccg aatcggctga tttttggagt
    23761 aaattggttt acttctttgc ggaaatcatt cgctttttat cgtttgatat tagtatcgga
    23821 gtggggatta ttctctttac ggtcttgatt cgtacagtcc tcttgccagt ctttcaggtg
    23881 caaatggtgg cttctaggaa aatgcaggaa gctcagccac gcattaaggc gcttcgagaa
    23941 caatatccag gtcgagatat ggaaagcaga accaaactag agcaggaaat gcgtaaagta
    24001 tttaaagaaa tgggtgtcag acagtcagac tctctttggc cgattttgat tcagatgccg
    24061 gttattttgg ccctgttcca agccctatca agagttgact ttttaaagac aggtcatttc
    24121 ttatggatta accttggtag tgtggataca acccttgttc ttccgatttt agcagcagta
    24181 ttcacctttt taagtacttg gttgtccaac aaagctttgt ctgagcgaaa tggcgctacg
    24241 actgcgatga tgtatgggat tccagtcttg atttttatct ttgcagttta tgcgccaggt
    24301 ggagtcgccc tatactggac agtgtctaat gcttatcaag tcttgcaaac ctatttcttg
    24361 aataatccat tcaagattat cgcagagcgc gaggccgtag tacaggcaca aaaagatttg
    24421 gaaaatagaa aaagaaaagc caagaaaaag gctcagaaaa cgaaataaat aaggaggaat
    24481 ctggtaatgg tagtatttac aggttcaact gttgaagaag caatccagaa aggattgaaa
    24541 gaattagata ttccaagaat gaaggctcat atcaaagtca tttctaggga gaaaaaaggc
    24601 tttcttggtc tatttggtaa aaaaccagcc caagtggata ttgaagcgat tagtgaaacg
    24661 actgttgtca aagcaaatca acaggtagta aaaggcgttc cgaaaaaaat caatgatttg
    24721 aacgagcctg tgaagacggt tagtgaagaa accgttgacc ttggtcatgt ggttgatgct
    24781 attaaaaaaa tagaggaaga aggtcaaggt atttctgatg aagtcaaggc tgaaatctta
    24841 aaacatgaaa gacatgccag cactatctta gaagaaactg gtcacattga gattttaaat
    24901 gaacttcaaa tcgaggaagc gatgagggaa gaagcaggcg ctgatgacct tgaaactgag
    24961 caagatcaaa ctgaaaatca agacttgaaa gagatgggct tgaaggtcga gcaaagttat
    25021 gatattgccc aggtggctac ggatgtgact gcctatgttc aagcgattgt ggatgacatg
    25081 gatgttgaag ctacactttc aaatgattat aaccgtcgta gcatcaatct acaaattgac
    25141 accaacgaac caggtcgtat tatcggctac catggtaaag tcttgaaggc cttgcaactg
    25201 ttggctcaaa attatcttta caaccgctat tccagaacct tctacgttac aatcaatgtc
    25261 aatgattatg tcgaacaccg tgcagaagtc ttgcagacct atgcgcaaaa attggcgact
    25321 cgtgttttgg aagaagggcg cagtcataaa acagatccaa tgtcaaatag cgaacgcaag
    25381 attatccatc gtattatttc acgtatggat ggcgtgacta gttactctga aggtgatgag
    25441 ccaaatcgct atgttgttgt agatacagaa taagtaaaat caggtttatc ctgatttttt
    25501 gctagttaga ggaggttaaa ctgatgttga ataagataag agactattta gactttgctg
    25561 gtttgcagta ccgtaatcct gataaagcgg gagcagagcg agagaagatg ctggcattcc
    25621 gccacaaagg acaagaggcc cgaaaggctt ttacagaact ggccaaagcc tttcaagcaa
    25681 gccatccaga atggcaactc caacagacta gccagtggat gaatcaggcc cagcgtttga
    25741 gaccacattt ttgggtttat ctacagagag acggacaagt gacagaacct atgatggcct
    25801 tacgtttgta tgggacatct actgactttg gaatttcttt ggaagtcagt ttcatcgaac
    25861 gtaagaagga tgagcaaaca ctgggcaagc aggccaaagt tttagacatt ccaaccgtta
    25921 aagggattta ttatctaacc tactctaatg gtcaaagtca acggtgggag gcgaatgaag
    25981 aaaagcgtcg tactttacgc gagaaggtga gaagtcaaga agttcgaaaa gttttagtga
    26041 aggtagatgt tcctatgaca gaaaattcgt ctgaagaaga aatcgtagaa ggcttattga
    26101 agtcttattc taaaattctt ccctattatc tagctacgag aaaataagat aatttgtaaa
    26161 acatcataaa tcatacagtc caagagtgaa cagtccgctg tgtaattctt ggtctttttg
    26221 tttgcgcttt cgcattatat aataaactta caaaaacaat tcaaaaggag aacaattatg
    26281 gaagtcgttt caagtgttct aaattggttt tctagcaata ttttgcagaa tcccgcattt
    26341 ttcgtaggtt tattggtgtt gataggatat gcacttttga aaaaacctgc ccatgacgtt
    26401 ttttcagggt ttgttaaagc aacagtaggg tatatgttgc ttaacgtggg tgctggtggt
    26461 ttggttacaa cctttcgtcc aatcttagca gctcttaact acaaattcca aattggtgca
    26521 gcggttatcg acccttactt tggacttgct gcagcaaaca acaaaattgc agcagagttt
    26581 ccagattttg ttggaactgc aactacagct ctattgattg gttttggaat aaatatcttg
    26641 ctcgtagctc ttcgaaagat tacgaaggta agaaccctct ttattactgg tcacatcatg
    26701 gtacaacaag ctgcaacagt atctcttatg gttctattct tagtaccaca attgcgcaat
    26761 gcttacggta cagcagcgat tggtatcatc tgtggacttt actgggcagt tagttcaaat
    26821 atgactgttg aggcaactca acgcttgact ggtggtggcg gatttgcgat tggtcaccaa
    26881 cagcaatttg caatctggtt tgtagataaa gtagcaggac gctttggtaa gaaagaagaa
    26941 agtttagaca atcttaaatt acctaagttc ctctcaatct tccacgatac agttgttgca
    27001 tctgctacct tgatgctcgt attcttcgga gccattcttt taatcttggg tccagacatt
    27061 atgtctaata aagaagtcat cacttcagga actctattca atcctgctaa acaagatttc
    27121 tttatgtaca ttatccaaac agcctttacc ttctcagttt acttgttcgt tttgatgcaa
    27181 ggtgtccgaa tgttcgtatc tgagttgaca aacgccttcc aaggtatttc aaacaaattg
    27241 ttgccaggtt cattcccagc ggttgacgtt gcagcttctt atggatttgg ttctccaaat
    27301 gctgtcttgt caggatttac ctttggtttg attggtcaat tgattacaat tgtcttgctc
    27361 atcgtcttta aaaatccgat tcttattatt acaggatttg taccagtgtt ctttgacaat
    27421 gcagccattg cggtctacgc tgataaacgc ggcggatgga aagcggctgt tatcctttcc
    27481 tttatatcag gtgtccttca agttgctcta ggagctcttt gtgtggccct tctcgatttg
    27541 gcatcttatg gtggctacca tggaaatatc gactttgaat tcccatggct tggatttgga
    27601 tatatcttca aataccttgg tattgttggt tatgtacttg tgtgtctctt cttgcttgtt
    27661 attcctcaac ttcaatttgc caaagcaaaa gataaagaga aatattacaa cggtgaagtt
    27721 caagaagaag cttagtatct agaaaaggag aaataaaatg gttaaagtat tagcagcgtg
    27781 cggaaatgga atgggttcat caatggttat caagatgaag gttgaaaatg ctctccgtaa
    27841 gcttaatcaa acagatttta cagtcaattc atgcagtgtc ggtgaagcta aaggtttagc
    27901 agtaggatat gacatcgtaa tcgcttctct tcatttgatt caagaattgg aagggcgaac
    27961 taatgggaag ttaattggtc ttgataactt gatggatgat aaagaaatca ccgaaaaact
    28021 cagtcaagca ctacagtaaa aggttggagg gggctggaca gaaactgaga gttatcgttt
    28081 ctgtccttct ccctctttaa ataaaggagg cagatatgaa tttaaaacaa gctttaattg
    28141 acaatgactc gatccgacta ggtttagagg ctaacaattg gaaagaagca gtcaaggtag
    28201 cagtagatcc cctaattgaa agtggggcaa ttttgccaga gtattacgat gctatcattg
    28261 aatcgactga agagtatggg ccttactata tcttgatgcc aggtatggct atgccccacg
    28321 ctagacctga agctggtgtg caaagtgatg ccttttcatt gattacctta caaaatcctg
    28381 ttgtattttc agatgggaaa gaggtatctg ttttgttggc actagcagca acaagttcaa
    28441 aaattcacac aagtgtagcc attccacaaa ttattgccct gtttgaatta gaagattcta
    28501 ttgcacgttt acaggcttgc cagactaaag aagatgtctt ggctatgatt gaagaatcta
    28561 aggatagccc ttatctcgaa ggattggatt tggaaagtta gaaagaggaa taaagaaatg
    28621 acaaaaagaa tacctaattt acaagttgca ttagaccatt cagacttgca aggagcgatt
    28681 aaagcagctg tttctgttgg tcaggaagta gatattatcg aagctggaac tgtttgcttg
    28741 cttcaagttg gaagtgaact ggctgaagtc ttgcgtagcc ttttcccaga taagattatt
    28801 gtggcagaca caaaatgtgc tgatgctggt ggaacagttg ctaaaaataa tgcggttcgt
    28861 ggagcagact ggatgacttg tatctgttgt gcaaccatcc ctactatgga agcagctcta
    28921 aaggctatca agactgaacg aggagaacga ggcgaaatcc agatcgagct ttatggcgat
    28981 tggacttttg aacaagctca gctttggcta gatgcaggta tctcacaagc tatttatcac
    29041 caatctcgtg atgctcttct tgctggtgaa acttggggtg aaaaagacct taataaggtt
    29101 aaaaaactca ttgacatggg cttccgtgta tctgtaacag gtggtctaga tgtagatact
    29161 ctcaaactct ttgaaggtgt tgatgtcttt acctttatcg caggtcgtgg aattacagag
    29221 gctgcggatc cagcaggagc agcgcgtgcc ttcaaggatg aaatcaaacg aatttggggg
    29281 taaatcatgg tacgtccaat tggaatttat gaaaaggcaa ccccaacaca ctttacttgg
    29341 ctagaacgtt taaattttgc caaggagtta ggctttgatt ttgtcgagat gtctattgac
    29401 gaacgtgacg agcgtttagc aagacttgac tggagtaagg aagaacgctt ggaagttgtc
    29461 aaagcaatct atgaaactgg tgttcgtatt ccttctatct gtttttcagg ccatcgtcgc
    29521 tacccattgg gttcaaaaga tccagttcta gaggaaaaat ctctagaact catgaaaaaa
    29581 tgtatcgaat tagctcaaga cttgggagtt cgtacgattc aattagctgg ttacgatgtt
    29641 tactatgagg aaaagtcacc ccagacacgc caacgtttta tcaaaaattt gagaaaagcc
    29701 tgtgactggg ctgaagaagc tcaggtggta cttgctattg aaattatgga tgatcctttc
    29761 atcagtagca tcgaaaaata tttggctata gaaaaagaga ttgactctcc cttcctcttt
    29821 gtatatccag atattggtaa tgtgtctgca tggcataatg atatctatag tgagttttat
    29881 cttggtcatc atgccatcgc agctctccat ctcaaggata cttatgcagt gacagaaagt
    29941 tcaaagggcc agttccgaga tgtacctttc gggcaaggtt gtgtcaaatg ggaagaagct
    30001 ttcgatattt taaaggaaac caattataat ggacctttcc taatcgaaat gtggtctgaa
    30061 aattgtgaaa cagtagaaga aacacgcgca gccgttcaag aggcgcaagc ttttctctat
    30121 ccactcatta agaaagcagg tttgatgtaa gatgaatcaa gtaatcaatg ctatgcgtaa
    30181 acgagtctgt gatgccaatc aatcattgcc aaaacatgga cttgtcaaat ttacctgggg
    30241 gaatgtatct gaagttaatc gcgaactcgg tgtcattgtt atcaaaccat caggcgtgga
    30301 ttatgacgaa ttgacacctg aaaacatggt agtgactgat ctagatggta agatcctaga
    30361 aggggattta agaccatctt ccgacctccc aactcatgtg caattatata aggcttggtc
    30421 agaaattggt agtgtggttc acacccattc gacagaagct gttggttggg ctcaggcagg
    30481 tcgtgatatt cctttctacg gaacaaccca tgcagattat ttctacggtt caatcccttg
    30541 cgcccgtagt ttgaccaagg acgaagtaga agtggcctat gaaaaagata ctggcctggt
    30601 tatcgtagaa gagtttgaac atcgcggact taacccggtt gaagtaccag gaattgttgt
    30661 acgcaatcac ggtccattca cctggggcaa aaatccagag aatgctgttt atcactctgt
    30721 cgtactagag gaagtatcaa agatgaatcg ctttacagaa caaatcaatc caagagttgg
    30781 acctgctccc cagtacatac tagaaaaaca ctaccaacgt aaacatggac caaatgctta
    30841 ttatggtcaa aagtaagaac gatgaaggag gagaaaaaga taaatttagc tcctcttttt
    30901 acatttgatt tttattgaga gtaaagttgg aattgaagta attttaaaag attttttaga
    30961 aatagcgctt gatatatata tggtaaaata aaaagaattg ctgtgatatc aatagatttg
    31021 ggggattttt taatatggta ctggataagg caagttgtga tttgcttcaa tatttgatgg
    31081 atcaagaaac gtccaaaacg attatggcga tttcgaaaga tttgaaagag tcaagaagga
    31141 aaatttatta tcacattgac aaaatcaatg ctgctctggg tgacgaggcg cttcacatca
    31201 ttagtattcc acgaattggt attcacttaa cggaagagca gagagatgct tgttgtaaac
    31261 tattatcgga agtagattcg tacgattata tcatgagtgc gcatgaacgt atgatgataa
    31321 tgttactatg gataggtatt tctaaagaac gtattacgat tgaaaaattg atagagttaa
    31381 cagaggtatc taggaatact gttctcaatg atttgaatag tattcgttat caactaactt
    31441 tggaacaata tcaggtgatc ttgcaagtga gcaagtcaca gggataccac cttcatgccc
    31501 accctcttaa taaaattcag tatcttcaat cgcttctata tcatattttt atggaagaaa
    31561 atgccacttt tgtatctatt ttagaagata agatgaaaga gaggttagat gatgagtgtt
    31621 tgctttctgt tgaaatgaac caatttttta aggaacaggt tcctttagtt gaacaagatt
    31681 tagggaagaa aataaaccat catgaaataa cttttatgtt gcaggttcta ccttatttgc
    31741 tgttaagctg tcataatgtt gaacagtatc aagaaagaca tcaggatata gagaaagaat
    31801 tttctttgat aagaaaaaga atagagtatc aggtgtctaa gaaattagga gaacggttgt
    31861 ttcaaaagtt tgaaatttct ttgtcaggac ttgaagtttc tcttgtagct gttctcctcc
    31921 tctcctatcg taaagatttg gatattcatg cagaaagtga tgattttcgg caattaaaac
    31981 ttgctttaga agaatttatc tggtattttg aatcacaaat ccgaatggag attgagaaca
    32041 aggatgattt gttacgaaat ttgatgatcc actgtaaagc cttgttattt agaaagactt
    32101 acggtatttt ttctaaaaat cctctaacaa aacaaattcg atccaagtat ggagaattat
    32161 ttttagtcac tagaaaatct gcggaaattt tagaaggagc atggtttatt cggctaacag
    32221 acgatgatat tgcctatttg acgattcata ttggaggatt tttaaaatat acaccatcgt
    32281 ctcaaaaaaa tatgaaaaaa gtttatctcg tttgtgatga aggtgttgcg gtttcgagac
    32341 ttttgctgaa acaatgcaaa ctttattttc caaatgagca aattgacact gtatttacaa
    32401 cagaacaatt taagagtgtg gaagatattg cacaagttga tgtagtgatt actactaatg
    32461 atgatttgga tagcagattt ccgattttaa gggttaatcc tatccttgaa gcagaagata
    32521 ttttgaaaat gctagactat cttaaacaca atatatttcg taataagagc aaaagtttca
    32581 gtgaaaatct ttctagtctt atttcgtctt atattgtaga tagcaagttg gctagtaagt
    32641 tccaagaaga ggttcaaaca cttataaatc aagaaatagt agttcaagct tttttggaag
    32701 atatttgaag gacagtccaa tgatgaacac aaacctgtgt ttttcttggt cttttttagt
    32761 gttttgaagg gtggtatact aatctcaaag ataacaatta tatccaaagg aggcaacata
    32821 tgccaaacgt caaagaaatt acaagagagt catggatttt agccactttc ccagagtggg
    32881 gaacatggtt gaacgaagaa atcgaagaag aagtcgtacc tgaaggcaac tttgccatgt
    32941 ggtggctagg caactgtggt acttggatta agacaccagc tggtgctaac gttgtcatgg
    33001 acctttggtc aaaccgtgga aaatcaacca aaaaagtgaa agatatggtt cgtgggcacc
    33061 aaatggcaaa tatggcaggt gttcgtaagt tgcaaccaaa cttgcgtgtt cagccaatgg
    33121 ttatcgatcc atttgctatc aacgaactag actattactt agtttcacac ttccacagtg
    33181 atcatatcga cccatacaca gctgcagcaa ttctcaacaa tcctaagtta gagcatgtta
    33241 agtttatcgg tccttaccac tgtggacgaa tctgggaagg atggggtgtt ccaaaagaac
    33301 gtatcatcgt tgttaaacca ggtgacacta tcgaattaaa agatatgaag attcatgcag
    33361 tagaatcatt tgaccgtact tgcttggtaa ctctcccagt gaacggtgct gatgagacag
    33421 gcggtgaact tgctggcttg gctgttacag atgaagaaat ggctcaaaag gctgttaact
    33481 atatctttga aacaccaggt ggaaccatct atcatggtgc agattctcac ttctcaaact
    33541 attttgcaaa acatggtaaa gactttaaaa ttgatgttgc tttgaataac tatggtgaaa
    33601 atccggtagg tatccaagac aaaatgacat ctatcgacct tcttcgtatg gcagaaaatc
    33661 tgcgtaccaa agtcattatc ccagttcact atgatatctg gtctaacttc atggcttcta
    33721 ctaatgagat tctagaactt tggaaaatgc gaaaagatcg cttgcaatac gatttccatc
    33781 catttatctg ggaagttggc ggtaagtaca cttatcctca agatcaacac ttagtagaat
    33841 accatcatcc acgtggtttt gatgattgtt ttgaacaaga ctctaacatt caatttaaag
    33901 ctttgctata atataaaaat attctttgga ggttatccgt atgttgcatg atacggataa
    33961 ttttcatata atagtaaaat agaatgtgtg attcaataat cacctcaaat agaaaggaaa
    34021 ttctatgtca aatctatctg ttaatgcaat tcgttttcta ggtattgacg ccattaataa
    34081 agccaactca ggtcatccag gtgtggttat gggagcggct ccgatggctt acagcctctt
    34141 tacaaaacaa cttcatatca atccagctca accaaactgg attaaccgcg accgctttat
    34201 tctttcagca ggtcatggtt caatgctcct ttatgctctt cttcaccttt ctggttttga
    34261 agatgtcagc atggatgaga ttaagagttt ccgtcaatgg ggttcaaaaa caccaggtca
    34321 cccagaattt ggtcatacgg cagggattga tgctacgaca ggtcctctag ggcaagggat
    34381 ttcaactgct actggttttg cccaagcaga acgtttcttg gcagccaaat ataaccgtga
    34441 aggctacaat atctttgacc actatactta cgttatctgt ggagacggag acttgatgga
    34501 aggtgtctca agcgaggcag cttcatacgc aggtttgcaa aaacttgata agttggttgt
    34561 tctttatgat tcaaatgata tcaacttgga tggtgagaca aaggattcct ttacagaaag
    34621 tgttcgtgac cgttacaatg cctacggttg gcatactgcc ttggttgaaa atggaacaga
    34681 cttggaagcc atccatgctg ctatcgaaac agcaaaagct tcaggcaagc catctttgat
    34741 tgaagtgaag acggttattg gatacggttc tccaaacaaa caaggaacta atgctgtaca
    34801 cggcgcccct cttggagcag atgaaactgc atcaactcgt caagccctcg gttgggacta
    34861 cgaaccattt gaaattccag aacaagtata tgctgatttc aaagaacatg ttgcagaccg
    34921 tggcgcatca gcttatcaag cttggactaa attagttgca gattataaag aagctcatcc
    34981 agaactggct gcagaagtag aagccatcat cgacggacgt gatccagtcg aagtgactcc
    35041 agcagacttc ccagctttag aaaatggttt ttctcaagca actcgtaatt caagtcaaga
    35101 tgccttgaat gttgtggcag ctaaattacc aaccttccta ggtggatcag ctgaccttgc
    35161 tcactcaaac atgacttata tcaagacgga tggacttcaa gacgatacca atcgcttgaa
    35221 tcgtaacatt cagtttggtg ttcgtgaatt tgcaatggga acaatcttga acgggatggc
    35281 ccttcatggt ggacttcgtg tatacggtgg aactttcttc gtcttctctg actatgtgaa
    35341 ggcagctgtc cgtttgtcag ccttacaagg acttcctgtg acttatgtct ttacccatga
    35401 ttcaatcgca gttggggaag atggtccgac tcacgaacca gttgagcatt tagcaggtct
    35461 tcgtgctatg ccaaatctaa atgttttccg tccagcagat gcgcgtgaaa cgcaagcagc
    35521 ttggtacctt gcagtgacaa gtgagaaaac accaactgcc cttgtcttga cacgtcaaaa
    35581 cttgactgtt gaagatggaa cagacttcga caaggttgct aaaggtgctt atgttgtata
    35641 tgaaaatgca gccgactttg ataccatctt gattgcgaca ggttcagagg ttaatcttgc
    35701 tgtctcagct gctaaagaat tggctagtca aggcgaaaaa atccgcgtag tcagcatgcc
    35761 atctacagat gtctttgata aacaagatgc agcttacaag gaagaaattc ttccaaatgc
    35821 agtccgccgt cgtgttgcag tcgaaatggg tgcaagtcaa aactggtaca aatatgttgg
    35881 tctcgatggt gccgttctag gtattgatac cttcggagcc tctgccccag caccaaaagt
    35941 attggcagaa tatggcttta ctgtcgaaaa tcttgtaaaa gttgttcgaa atttgaaata
    36001 atcctaaaaa tcagggcgta agctctggtt tttcttacca gaaaagtaag gtacaatctt
    36061 gtaaaagtag ctgaaatttg atatagtagt cctatgtaaa agacaaagga gaaaacaatg
    36121 aatccaaata ttactttttt aatcatgctt gtaggtatga tggccttgat gttctttatg
    36181 caacgttctc aaaagaaaca agctcaaaag cgtatggaaa gcttaaataa actacaaaaa
    36241 ggctatgaag tgattacaat cggtggactt tatggaacag tcgatgaagt agatacggag
    36301 aagggaacaa tagttcttga cgtagatgga gtttacttga cttttgaact agctgctatc
    36361 aagacagtat taccgctgaa agaaacagct tcactagaag gcgcaattga aaaataagac
    36421 gggatcacga actcccgttt tctataaaag aaaggaaatg ggatgaaaaa attagtcttt
    36481 gtctgtctgg gaaatatttg ccgtagccct atggccgagt ttgttatgaa atcaatgaca
    36541 gataactacg aaatccaaag tcgagcaact tcctcttggg aacatggcaa tccgattcat
    36601 aaggggactc agggaatttt tcaagagtat gagattcctt atgacaagaa caagacatcg
    36661 cttcagatta gtaaggaaga ttttgaagcc tttgattata ttatcggaat ggacgcttca
    36721 aatatttctg acttacgtca gatgtgtcca gtagactgtc aagataagat ttactcattt
    36781 tcatctgaaa gtgttccaga cccttggtat acaggagatt ttgaagaaac ctatcgacgt
    36841 gttcaagagg gctgtcaagc ttggttagaa cgtttagaaa aggagagtta aggtggaaaa
    36901 tcttacgaat ttttacgaaa agtatcgtgt ctatctgact cgtccacgtt tagagctttt
    36961 ggcagtagtt accattgttt tctgtgctgt actcgtcttt tttctaaata ttccaggaaa
    37021 aggtgtctta aaactcgata atggaacgat tgtttatgat ggcagtcttg tccgtggtaa
    37081 aatgaatggc caaggtacca ttaccttcca aaatggagac caatatacag gtggcttcaa
    37141 caatggagcc ttcaacggaa aaggtacctt tcaatctaaa gaaggctgga cctacgaagg
    37201 tgattttgta aatggtcagg ctgaaggaaa agggaaacta acaacagaac aagaagtcgt
    37261 ttatgaagga acttttaaac aaggcgtttt tcaacaaaaa taaagcctcc tatcaaagga
    37321 ggtattatta gaatcacaag gtaagcgctt acctgtgaat ccctttcttt ccaaatccct
    37381 cttccaagca agtttgtgaa ataaaaaata tttgaaataa atttcacaaa cttcaaagat
    37441 aaaacttgat aagaaaagaa aatgagaaaa gtttcacaag agtttaaaaa ttctttgtga
    37501 aatgtttatg aaactgttta caaagttgaa ataatgcgtt ataataaact tgtgaaaaaa
    37561 ttaacaaagg atatcgttcc ttgaaagcta tggaggaaaa tatggctgat aaaaaaactg
    37621 tgacaccaga ggaaaagaaa ctcgttgctg aaaaacacgt agatgagttg gttcaaaaag
    37681 ctctagttgc ccttgaagaa atgcgtaaat tggatcaaga acaagttgac tacatcgttg
    37741 ccaaagcatc agtagcagct ttggatgccc acggagaatt ggctttacat gcctttgaag
    37801 aaacaggacg tggtgtattt gaagacaaag caactaagaa cttgtttgct tgtgaacacg
    37861 tagtaaacaa catgcgccac actaagacag ttggcgttat cgaagaagac gatgtaacag
    37921 gattgactct tattgctgaa ccagttggtg ttgtttgtgg tattactcca acaacaaacc
    37981 caacatcaac agcaatcttc aaatcattga tttcattgaa gacacgtaac ccaatcgtct
    38041 ttgccttcca tccatcagca caagaatcat ctgctcatgc agctcgtatc gtccgcgatg
    38101 cagctatcgc agctggtgct cctgaaaact gtgtacagtg gatcactcaa ccatctatgg
    38161 aagcaactag tgcccttatg aaccacgaag gtattgcaac aatccttgca acaggtggta
    38221 atgccatggt taaagccgca tactcatgtg gtaaaccagc tcttggggta ggtgccggaa
    38281 acgttccagc ttatgttgaa aaatcagcaa acattcgtca agcagcacac gatatcgtca
    38341 tgtctaaatc atttgataac ggtatggtct gtgcatctga acaagcagtt atcattgata
    38401 aagaaattta cgatgaattt gtagcagagt tcaaatctta ccacacttac tttgtaaaca
    38461 aaaaagaaaa agctcttctt gaagagttct gcttcggcgt caaagcaaac agcaaaaact
    38521 gtgctggtgc aaaattgaac gctgacatcg ttggtaaacc agcaacttgg attgcagaac
    38581 aagcaggatt tacagttcca gaaggaacaa acattcttgc tgcagaatgt aaagaagttg
    38641 gcgaaaatga gccattgact cgtgaaaaat tgtcaccagt tattgcagtt ttgaaatctg
    38701 aaagccgtga agatggtatt actaaggctc gtcaaatggt tgaatttaac ggtcttggac
    38761 actcagcagc tatccacaca gctgacgaag aattgactaa agaatttggt aaagctgtta
    38821 aagctattcg tgttatctgt aactcacctt ctacttttgg tggtatcggg gacgtttaca
    38881 atgccttctt gccatcattg acacttggat gtggttctta cggacgcaac tcagttgggg
    38941 ataacgttag tgccattaac ctcttgaata tcaaaaaagt cggaagacgg agaaataaca
    39001 tgcaatggat gaaacttcct tcaaaaacat actttgaacg tgattcaatt caataccttc
    39061 aaaaatgtcg tgacgttgaa cgtgtcatga tcgttactga ccatgccatg gtagagcttg
    39121 gtttccttga tcgtatcatc gaacaactgg accttcgtcg caataaggtt gtttaccaaa
    39181 tctttgcgga tgtagaaccg gatccagata tcacaactgt aaaccgtggt actgagatta
    39241 tgcgtgcctt caaaccagat accatcatcg cactcggtgg tgggtctcca atggatgctg
    39301 ccaaagtaat gtggctcttc tacgagcaac cagaagtgga cttccgtgac cttgtccaaa
    39361 aattcatgga tatccgtaaa cgtgccttca agttcccatt gcttggtaag aagactaaat
    39421 tcatcgcgat tccaactaca tctggtacag gatctgaagt aacaccattt gccgttatct
    39481 ctgataaagc aaacaaccgt aaatacccaa tcgctgacta ctcattgaca ccaactgtgg
    39541 caatcgtaga tcctgctttg gtattgacag ttccaggatt tgttgctgct gatactggta
    39601 tggacgtatt gactcacgcg acagaagcat acgtatcaca aatggctagt gactacactg
    39661 atggtttagc acttcaagcc attaaattgg tctttgaaaa tctcgaaagc tcagttaaga
    39721 atgcagactt ccactcacgt gagaaaatgc ataacgcttc aacaatcgct ggtatggcct
    39781 ttgccaatgc cttcctaggt atttctcact caatggccca taagattggt gcgcaattcc
    39841 acacaatcca cggtcgtaca aatgctatct tgcttccata cgttatccgt tacaacggta
    39901 cacgtccagc taagacagca acatggccta agtacaacta ctaccgtgca gatgaaaaat
    39961 accaagatat cgcacgcatg cttggacttc cagcttctac tccagaagaa ggggttgaat
    40021 cttacgcaaa agctgtctac gaactcggtg aacgtattgg gatccaaatg aattttagag
    40081 accaaggaat tgacgaaaaa gaatggaaag aacattctcg tgaattagcc ttcctggctt
    40141 atgaagacca atgttcacca gctaacccac gtcttccaat ggtagaccat atgcaagaaa
    40201 tcatcgaaga tgcatactat ggctacaaag aaagaccagg acgccgtaaa taattgttta
    40261 tcagtctaga agcaagacaa aaactcaatt tgagggaaag atccagtact ttttctatga
    40321 taaaaggcat cctatcaagg tttttgaaca cctgatagga tgccttttta tgatattgag
    40381 gcctttttgc cctttttgaa aaactagaat agaaacaaaa tatataatag attgaaactg
    40441 gaatagtaca cttctgcttc taaaacattg ttagaattcg atttgactgt cctgatcgat
    40501 ttgtcctgtt cttatttcat tttaatatat aaaaaatat
//
LOCUS       DAVBNZ010000013        40481 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000013 DAVBNZ010000000
VERSION     DAVBNZ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.013"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(<1..69)
                     /locus_tag="VQ860_000727"
     CDS             complement(<1..69)
                     /locus_tag="VQ860_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3119190.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARI"
     gene            complement(512..967)
                     /locus_tag="VQ860_000728"
     CDS             complement(512..967)
                     /locus_tag="VQ860_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119191.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(1242..2979)
                     /locus_tag="VQ860_000729"
                     /pseudo
     CDS             complement(1242..2979)
                     /locus_tag="VQ860_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            complement(3142..4026)
                     /locus_tag="VQ860_000730"
     CDS             complement(3142..4026)
                     /locus_tag="VQ860_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET3119192.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLINKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(4138..4992)
                     /locus_tag="VQ860_000731"
     CDS             complement(4138..4992)
                     /locus_tag="VQ860_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET3119193.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(5050..5808)
                     /locus_tag="VQ860_000732"
     CDS             complement(5050..5808)
                     /locus_tag="VQ860_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3119194.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(5870..6058)
                     /locus_tag="VQ860_000733"
     CDS             complement(5870..6058)
                     /locus_tag="VQ860_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET3119195.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(6381..6947)
                     /locus_tag="VQ860_000734"
     CDS             complement(6381..6947)
                     /locus_tag="VQ860_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119196.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(7215..8894)
                     /locus_tag="VQ860_000735"
                     /pseudo
     CDS             complement(7215..8894)
                     /locus_tag="VQ860_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(8986..9147)
                     /locus_tag="VQ860_000736"
     CDS             complement(8986..9147)
                     /locus_tag="VQ860_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119197.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(9831..10145)
                     /locus_tag="VQ860_000737"
     CDS             complement(9831..10145)
                     /locus_tag="VQ860_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119198.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(10111..10500)
                     /locus_tag="VQ860_000738"
     CDS             complement(10111..10500)
                     /locus_tag="VQ860_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3119199.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(10888..11682)
                     /locus_tag="VQ860_000739"
     CDS             complement(10888..11682)
                     /locus_tag="VQ860_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119200.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(11682..12689)
                     /locus_tag="VQ860_000740"
     CDS             complement(11682..12689)
                     /locus_tag="VQ860_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3119201.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(12689..13696)
                     /locus_tag="VQ860_000741"
     CDS             complement(12689..13696)
                     /locus_tag="VQ860_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3119202.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(13686..14711)
                     /locus_tag="VQ860_000742"
     CDS             complement(13686..14711)
                     /locus_tag="VQ860_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3119203.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(15104..15322)
                     /locus_tag="VQ860_000743"
     CDS             complement(15104..15322)
                     /locus_tag="VQ860_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3119204.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(15568..15846)
                     /locus_tag="VQ860_000744"
     CDS             complement(15568..15846)
                     /locus_tag="VQ860_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119205.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(16060..17691)
                     /gene="rlmD"
                     /locus_tag="VQ860_000745"
     CDS             complement(16060..17691)
                     /gene="rlmD"
                     /locus_tag="VQ860_000745"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3119206.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRGLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(17765..18739)
                     /locus_tag="VQ860_000746"
     CDS             complement(17765..18739)
                     /locus_tag="VQ860_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET3119207.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(18813..19427)
                     /gene="pmp23"
                     /locus_tag="VQ860_000747"
     CDS             complement(18813..19427)
                     /gene="pmp23"
                     /locus_tag="VQ860_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET3119208.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(19427..20401)
                     /locus_tag="VQ860_000748"
     CDS             complement(19427..20401)
                     /locus_tag="VQ860_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET3119209.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(20409..21665)
                     /locus_tag="VQ860_000749"
     CDS             complement(20409..21665)
                     /locus_tag="VQ860_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET3119210.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFLSYSVDPETELLDFDAIL
                     KQAQEVKLKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(21727..22158)
                     /locus_tag="VQ860_000750"
     CDS             complement(21727..22158)
                     /locus_tag="VQ860_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3119211.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(22160..22759)
                     /locus_tag="VQ860_000751"
     CDS             complement(22160..22759)
                     /locus_tag="VQ860_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET3119212.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(22746..23585)
                     /gene="prmC"
                     /locus_tag="VQ860_000752"
     CDS             complement(22746..23585)
                     /gene="prmC"
                     /locus_tag="VQ860_000752"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET3119213.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(23585..24664)
                     /gene="prfA"
                     /locus_tag="VQ860_000753"
     CDS             complement(23585..24664)
                     /gene="prfA"
                     /locus_tag="VQ860_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET3119214.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(24674..25153)
                     /locus_tag="VQ860_000754"
     CDS             complement(24674..25153)
                     /locus_tag="VQ860_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3119215.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVATLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDRNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEIAENEVVAIYDLTIEK"
     gene            complement(25143..25742)
                     /locus_tag="VQ860_000755"
     CDS             complement(25143..25742)
                     /locus_tag="VQ860_000755"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET3119216.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFTPMITSNKEQNYDN"
     gene            25865..26047
                     /locus_tag="VQ860_000756"
     CDS             25865..26047
                     /locus_tag="VQ860_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET3119217.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            26184..27557
                     /gene="mnmE"
                     /locus_tag="VQ860_000757"
     CDS             26184..27557
                     /gene="mnmE"
                     /locus_tag="VQ860_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET3119218.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(27604..28539)
                     /gene="dapA"
                     /locus_tag="VQ860_000758"
     CDS             complement(27604..28539)
                     /gene="dapA"
                     /locus_tag="VQ860_000758"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET3119219.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(28595..29671)
                     /locus_tag="VQ860_000759"
     CDS             complement(28595..29671)
                     /locus_tag="VQ860_000759"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET3119220.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(30013..30085)
                     /locus_tag="VQ860_000760"
     tRNA            complement(30013..30085)
                     /locus_tag="VQ860_000760"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30050..30052),aa:Thr,seq:ggt)
     gene            complement(30185..30694)
                     /locus_tag="VQ860_000761"
     CDS             complement(30185..30694)
                     /locus_tag="VQ860_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET3119221.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(30692..30788)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            30817..31248
                     /locus_tag="VQ860_000762"
     CDS             30817..31248
                     /locus_tag="VQ860_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET3119222.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            31330..31707
                     /gene="mscL"
                     /locus_tag="VQ860_000763"
     CDS             31330..31707
                     /gene="mscL"
                     /locus_tag="VQ860_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET3119223.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(31749..32722)
                     /locus_tag="VQ860_000764"
                     /pseudo
     CDS             complement(31749..32722)
                     /locus_tag="VQ860_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
     gene            32877..34100
                     /gene="pepT"
                     /locus_tag="VQ860_000765"
     CDS             32877..34100
                     /gene="pepT"
                     /locus_tag="VQ860_000765"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET3119224.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(34136..34693)
                     /locus_tag="VQ860_000766"
     CDS             complement(34136..34693)
                     /locus_tag="VQ860_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119225.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENLESNNGSDADFDKVDALLDQLSAKSKDKTALLESTKAILV
                     LNHQIQSKASASEETSPARNAEANSDNTSAENQPNATAESNIEIASDENKPSNTRDSK
                     PAESTSENETTESSTTTGNQEKPVE"
     gene            34658..34879
                     /locus_tag="VQ860_000767"
     CDS             34658..34879
                     /locus_tag="VQ860_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119226.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(35150..36161)
                     /locus_tag="VQ860_000768"
                     /pseudo
     CDS             complement(35150..36161)
                     /locus_tag="VQ860_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(36387..39506)
                     /gene="phtE"
                     /locus_tag="VQ860_000769"
     CDS             complement(36387..39506)
                     /gene="phtE"
                     /locus_tag="VQ860_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET3119227.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKKLSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLPETGNSTS
                     DSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(39717..>40481)
                     /gene="phtD"
                     /locus_tag="VQ860_000770"
     CDS             complement(39717..>40481)
                     /gene="phtD"
                     /locus_tag="VQ860_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HET3119228.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRVPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
BASE COUNT        11844 a         8183 c         6698 g        13756 t
ORIGIN      
        1 aattcgtgca aattcaggtt gtgttaagtc atgtgtttta cgtaaggatt ttatgttctt
       61 tccaatcata gtaaactcct ttatttttat aattcaatta tagcataaaa aagtataacg
      121 caccaatttt ggtgcgttat actttttttc tagcctaaac tttacttcta taaaagtcac
      181 ctaaagagcc ataaatattt attcttgtat taattttttc gatgcgcaaa cgatatctac
      241 aaatacatct ataacgattc accttttagg atttttattg tcaaaattgc ctttatctac
      301 aaagacaaaa tgcttataaa atagcttgaa atcaaggatt atcacctttt tcgttgtagc
      361 aacactccac atgtgattat taggctatta gcaaagcgta tccaatacct caataaagtg
      421 ttgtttttac tgatatttta actatattgt atagtctact atttaaatct caattaggat
      481 attttataga atacccaaaa ttcaacaata actaaaagta agattccatt gtatttcctt
      541 gttggtcttt catatcacga attttatttt tcagaatatt aaagttacaa atttcatctc
      601 taatatcgtt atccgctctg tagccattaa tcatctcagt cagagttttc cctttactac
      661 cattctttat agtagtattt actcttttta tactgctttc aaaaggctca tatgttttat
      721 acttaattac ttcgtcttta aaattaaata aaggtgtatc cggcttagca ttccataaaa
      781 taatcaacca cattatagca ttataaagct gctttgcagt ttcattccac ttttcaggtt
      841 gtaaatttcc actccctgta ttgtcatatt cttgtctatt atttacatga gaatcaccta
      901 caagtggatt aaaaagaggt agccctttgt gattaattag ttctaaaaaa tcccttgccg
      961 cacccatgca acactgaata acttccttct tgccatcaat tttactctca gcgataaata
     1021 cataatattc atcttcaata gttgctcctg catcactatg tttttgttga tttgctaaca
     1081 gcttaatatg tgctttaggc taaacttcaa aatctctaac aattctttgt cttgtttcat
     1141 gtcctctaca attcatttaa gttctccttt acaagtttag taactagcct tattatacta
     1201 tataagatat gaaatgtacc ataatcttca tcaactagtt tttagaaaat cacaaatcca
     1261 tctggagaga tgacaagctg attctccaat tcttggcaat tgcttgctag tgctactgct
     1321 tctttctcta aaagataatc ttctgttgat tggttgaata ttgctttgag gatccgtcct
     1381 tcgtatttcc attccagagc tactaaatca gatttgattt cttgaaggct atacttgcca
     1441 tgcgaaataa ttactgacgc gtatttccga atcttaatca gcctcttcat aaagttcagc
     1501 atatcattgt cacttgatac acgttcccaa ggcatacaac gacgacaatc tggatctggt
     1561 cctccagtca aggctagctc ggttccgtaa taaatgcacg gtgttccttt ttgtaaaaag
     1621 agaaaggcta aggctgattt aaccagttga acatcttcat tggccgtcca caggattcgc
     1681 tctgtatcat gtgaatccaa gagattaaac atgacctctg aaatctgctg cttgtaatac
     1741 atagactctc cattgatttc atcgatgaac tggtctgtct tcttaattcc tcgtaagaaa
     1801 tagtccttga tactatcaga taaaggataa ttcatgatgg catggaactc atctccattt
     1861 agccaaggct gagatgtatg ccagacttct cctaggatat aaagatcagg atttttagct
     1921 aaaactgcct tacgaaaatc cttccagaac tgatggtcaa tctcattagc cacatccaaa
     1981 cgccaagcat cgatattaaa ctcttcaatc caataagtcg caacctttaa aagataattc
     2041 ttgacctctg gattggctgt atttagctta ggcatatagt cctcgaaacc aaaaacatga
     2101 tagggtaagt ctctcttatt aactagtttt tcagttgtca ctgggaattg ttgaatatgg
     2161 aaccaatcct tataagcaga ctgttcacca tttttgacga catttttcca ttgaagagat
     2221 tgcgaaccaa tatgattaaa taccgcatcc agcatgactt tcatgccacg atgatgcgct
     2281 tgatccacca gttcccgaaa ggtctccttg tctccaaaat gacggtcaat ttcaaagtaa
     2341 tctgtcgtat tgtacttgtg attgcttgta gattcaaaga tgggacaaag atatagtcca
     2401 gtaataccca agtcttgcaa gtaatccata tgatcaataa tcccctgtaa atcaccacca
     2461 aagaaatcat cgctcttagg tgtgacagat gaatcccagt ctaaagtccc ttctgggttt
     2521 aatagagcat tgccattggc aaatctttca ggaaatatct gataccatac cgtatttgaa
     2581 acccagtcag gaaccttgca ggcatcaatc ttgaagataa ggcaacttaa atccattccc
     2641 aattgcatga agattttcta gagaattttc cacacaccct ttatcgccat acaaaatatt
     2701 ttgaccttct gtatctctga gctcaaagag atactggata cgtgcaaagt caactgacac
     2761 ttcaacctgc caatggtcaa ataaggtacc agaagttatc ttgaccattt cttttgtatc
     2821 ctgataaaac tcctccataa agataaaagg gtccccatag tgcaagttga tgctttcaat
     2881 gtcccctttc ttagttcgaa ttcgaatatg gagtttctta tccttataaa gataggcata
     2941 ctccgactca ggcctatggt aaatagcact caattccatc aatttgtctc ctaaagtatt
     3001 cattcaaatt ttacgcaaac gttttcaaac tcaatgaatc cagtatacta tttttgtaaa
     3061 ctatttgcaa ggaatgtccg ttgttaaagg aactatcttt taaagtatac aaaaagcctt
     3121 aaaaaaggct ttctctatat actaatcctc tttcggtttt gaaaatactt ctactcgctg
     3181 agctaggact ttgatttcta caggtaggtt atctgattta tctccgtcaa catctgactc
     3241 caattcacta tctgaagaga ttttaatatt acgcgctttg atatactcga tattatcatt
     3301 tgcgacaaca tcccctttta ataaatcagg aatgacggat aatttggaga atatagaggc
     3361 atctttcaga atcaaaatgt tggcatagcc gtccttgttt tcttcaaaga ttttcttatc
     3421 agcgaagtaa tttgtcaaaa ggaccaaaac atggctagct tcaccaacat aatttccatt
     3481 ttctgtctca accttaatgt taaagacctg atctgtcatg acagacttca tggtatttac
     3541 agcataggtt aaaataccga attttgtttt gtcctctatt tcaacattgt gaatcgcctc
     3601 aggcagagaa ccgatactaa agatataacc aaaatagttg tcatttgctt taccgatatc
     3661 aatcttattg attaaatcaa aatccagttc gtcaattgcg ccatcgatgt cttgattgat
     3721 ttccaaaagt tttgtaatga ggttacccgt accgcctggg ataatcccta acttaggaat
     3781 gtagtctctc tcatcaatac ctgaaatgac ttcattgaca gttccatctc caccaaacac
     3841 aaccactgca tcatactgct cacgagaagc ttcttcagca aaatgtgttg catccagcgc
     3901 tttttcggta attttggttt caacatattc aaagtattct tttgctttat tctccagctt
     3961 ttctttgtaa tccaaagcct tctcgccacc agaagtaggg ttgataatta ccattgcttt
     4021 tttcattgat tttatcctta attttaaaca gaaatgttta catttcgtcg tatgcaagta
     4081 aatgtaatcc tattatacaa tgaaaataca gaaaagagaa atctgacata ctggagatta
     4141 atacgctttt attctatttt cccatcgcct aactacatcc tttaagggtt catccaagta
     4201 agaataggcc ttatccttga tccaatcagg aataccgtaa gctgcctctg ctatgctaca
     4261 agtgattgct gcgagagtat cactgtcgcc accaagtgag atggcatttc ttatcgcatc
     4321 ttcgaagtct ctactttcaa gaaaggcgat aatggcttga gggacagttt cctgacatgt
     4381 ttcgttaaaa cgatagttag gacggatttc atctaaagtt tgagatagat tgtaatcgta
     4441 ttctttttct atataatcct taattcgtct tttacactct gtaggattgt cgttaattga
     4501 ttgctcgtac tctctacaat aaccaccaaa gtaaaaacga catagaaaga tagcatcagc
     4561 tgtagccata gcgcctttga caccttctgg atgattatga gttacctctg cagaaagact
     4621 cgtaagtcct ctagatgatg gccacatacc agttttcgca taaaaaccac agtccatgat
     4681 ccaagcacat ggagaaatac gcatagctga tccattccca aagctattat aaggctcacg
     4741 gttatcgctg tttagccatg cattaaaccg agcaccgtaa tcagcattcg gatacattct
     4801 gccatatttc ttcatcgcgt caatgaaatc gtctttttgt ccaccattca taattgcttc
     4861 tgcaacagca caggtcataa ccgtgtcatc tgtaaaaaag cagtccttcc gaaataaagg
     4921 aaagtccttt gttttgatat tgttccattc gtaaacagaa ccgacaatat ctccaataat
     4981 tgctccaagc atcagattcc tccttgttca ttttgatgct ttttatattg gttatctacc
     5041 atatttattt tagaaaataa catcctgttg gattttaaaa atttcatttt tttcaaaata
     5101 gggttttacc atttctttcc acctagctct atgaaaattg attgatttta aaggagatag
     5161 gccataattt cccaatgcat aaccatcatt tacttcaaca acaagtgttc tgccatcgcg
     5221 agtaacaccg atatctagtc cataagctat tggcgcatct ttccaacatg atatcgcttc
     5281 atcaattaca cttgcatcaa attgtgcatg ataatcacct gtatagggtc gaacatctaa
     5341 tacgcgacca tctaacacaa aacaacgcca ttcagctatg aattctacaa cctcactaat
     5401 ccatatagga tagtcgaaag gtagaccaat acctattaaa tcatgggttc cattaacaac
     5461 tcttccagta aagacttttg aaccagcttt aggcttaata aattttcccc aattatcagg
     5521 tatattcaca atctctccta aaataccagc ataaatcttt cgaccataaa actctttaag
     5581 ctcaatagga tagtcatgaa ccggaacgtt taagcccatc atttttagta atgctctagt
     5641 ctccattata taatctacaa ctatatcttc acttgttaac tcttttattt cagaaaaaga
     5701 ttgatataaa ataacttctt ctccttgtaa gtaggcacct acttgagcat tgtatttatt
     5761 aattgaaacc tcacttggta atttactttg tctaatataa acaaccattt catcactcct
     5821 atatcactag tgttacacca atttgtaaaa aataatagca attttgctct tatttttttg
     5881 agtaaatagc ccccataata tcatcgaaat aatcaacggt atttaggagt aattcaataa
     5941 cctgggactt tgttagtcgc attccccttc tatctctagc atcttctact aaattttcaa
     6001 gtttctctag atttttatca tccaagctaa tcattattct atttttatcg gttgccattt
     6061 tcatcacctc gagttaattc tatcacaggt gtaacacttg tgtcaactgg cttttataat
     6121 acattagttt aaaagtggag aggattttta acacagtaac tttaaatctt tggtattaaa
     6181 aaattttcac aatatttata gaaataaaat ctgtctcaaa tcagttatca aatctagtat
     6241 aaattatgag cggctactct aatactttcc ctctaaacaa gaaaaagact tacactcaag
     6301 ggttttcttc cccccccttc gttataacgt tttgactctt ttactagcaa aggtatatac
     6361 tcacaaggaa ctttggttga ctattgaatc tctccaactt cttctttaac atatccttct
     6421 acatcttcaa tctctacaaa cattgggtct aagtgacaca agaaatgcca aacttcgatc
     6481 cctttttttc tgtaaagaat cgcttcaccg tcttcacttc cgaaaaagct tctgtcgatt
     6541 tcatatccgc ggctttctaa gaagtctttt gctttacgat agttcgtttc tcttgtttcg
     6601 acataggctt taacttcatg gttgttaacg acatatgcat caatttttga atatccttcg
     6661 atcactctat catttttgag ggataaattt gaaatctctt tccaaataat gtttacattt
     6721 tcctcaggat cgaacataaa tttagataaa ggaacaatat ttccgttaaa aataatttcc
     6781 atataatccg gtatgttttt aggattaaaa tactccactt caaaaccatc ttctgtttcc
     6841 agagtgtatc ccgggatttg agctacaaag gctttcccat cttctatgga atcaaatgct
     6901 actaaatctt tagaataatc attttggtac aattccaata taaccatcga taatctctcc
     6961 attttcatta tcaggctaat gtaaataagc acgtcacctg accaattcag gctctctgta
     7021 tcatctcatc atatttccta cttactttac gagtcctata cccagaacac accttatcga
     7081 ccttcggtct cacctcgtcg cattggctga acatctactt ttacttcgct gatgcttcaa
     7141 ctcgtacaag cagtgatacc gcctcagcgt gatgcgtcag tgggactcaa aaagtttggg
     7201 gaaccttttg aggattaact acgtttctct aataaactta cacattcaac ttgttcatca
     7261 ttgtccaaat ctatgttgag attttcttct ataattggta gcttaaaagt aatggatttt
     7321 agccattgtc cgttagattg tttttcttca taaacttgaa tttcagaaat caaagctgaa
     7381 attaactgcc tacgctctac atcattcatg actttataga gcttatcaaa atagatcaga
     7441 accttatata tgttatctcc tgtaagcttt tcagcttcaa tagtctgttt ctttgctttc
     7501 gcatcaatta gtgatgattc taattcatct attttgtcat acatacgata tagtctatca
     7561 tctaaatcct gtttccttct cttataatgc ttatcttcaa catctaaatt atctatttcc
     7621 tcaattagct taaactttgt agaatgactc tttctcaatt ccttttggta attatctatt
     7681 tctttttcta tttcagaggt atccaccttc atgttgattt tttcttgcat catagaagca
     7741 aatttcggat tacttactat cttgacaatc acctctgcaa cagcatcatc taacaattct
     7801 tctctaattt gcttactgaa tgtacactta tgacctctta tcatctgcct atggttacaa
     7861 ccatagtaat aaaaatcttt atactttgtg ccatctttct ttttcttgat acacttgttc
     7921 ccaaacattc ccactccaca tatcgggcat tttacaattc cagaaagcaa gtgtgtgcgt
     7981 gtatcttttc ctttattcac atgctcatat ttctttgctt gagattttag cttaacctga
     8041 gcagcttacc aaacttcatc ggaaactata gcttcatgta tcccttcaga tattagatat
     8101 tcatcttgtt caacctgctt atattcattt cttgtaccat gaactttttc taaagttctt
     8161 cttccaaatg ctattttccc attatataca ggattcttta atatctttct tataagacct
     8221 gcatcaaaca aaggattctt accattctgt cttgggattt ttctaattcc atgattctct
     8281 aagtatttag atatcccatt ggctcctatc gtagtattta catactggtc gaaaatcgtt
     8341 cttattgcaa ctgcctcttc ctcatttata aacagcttgc cgtcttcaag tttatatcca
     8401 tacggagcaa agccaccatt ccattttcct tcccttgctt tttgaatgca accttccatt
     8461 gtttgaatac ggatgttttc tctttctatt tcagccacag ctgataaaac agaaatcatt
     8521 agtttcccag catctttaga tgaatcaatg ccatcttcaa cgcagataag attaactcca
     8581 taatcctgca ttatctgaag tgtagaaaga acatcagcgg catttcttgc aaatcttgat
     8641 aacttaaaca caagaacaaa agatactcca tcttttccag attttatatc ttccatcatt
     8701 cgattgaact gtattctacc ttcaatagac ttgccagact tcccggcatc ttcatactct
     8761 ccaacaattt cataatcgtt gtaaatagca aaagctttca ttcgtgattt ttgtgcctct
     8821 aacgaatacc cctctatctg tattgacgta gatactcgtg tatagaggta tacttttatt
     8881 ttttcttttg acatagtatt aacctcaata taatttttct atatcatata taattttttt
     8941 aatttaagtt tggactatca tttcaagtat attataacac ttttattagt ccgtctcaat
     9001 ttgtgttttt gccatgtcaa aactattttt catctcttga ttttttgctg gcgttggatc
     9061 gggtagatta tctaaatcta aagcaccagc atattttgca atcagatttg ctattaaatc
     9121 agccaatcca ttccagtcat tgtccaatat atacctcctc taaagtttta tatctaataa
     9181 ttatttgttt aattaagttt tttgacattg acaagtgctt tggattagca acataggaat
     9241 ctcacctccg cctctattcc ggatgagccg gcttcaacct tagaagtatc attatcctca
     9301 ttttcttcat agcggatagg gtatccctcc ctatattcaa actcttactt atcgctcact
     9361 ttctttttac ttagcagaac tttttttgcc gaattattca gccgaaagat cttgacggat
     9421 aggttattac gctccaaaaa taattaacgt cttgtcttgg tctattcaat tgttaaggtt
     9481 caaaatttat cgagagttat taatcttttt aaaatttgac catcagaaaa tatttatctt
     9541 aatgtaacaa aattctataa attaccctct tatacttaac agtgaaaaga agtctttctt
     9601 ggtaaccaat tttgaaatag aatttgctta tataaaaagg tcaaattccc actgcataag
     9661 tagcagtgaa aattagaccc tcttggtaac tgtcatctaa aagtcttcta gcatttcttt
     9721 aattttctaa tcgcctttaa agtgtcatat ttatattttt ttatctctgg catactttga
     9781 taccttttta gacttaaagt ctttaatagt gcctttccac ctctttttat ctataaagat
     9841 tctcctacat cataattcat ttttttattt aaacctttct gtcttagttt gtctttatct
     9901 tcttcatacc attttaagat tgtcacatag tggttttgat aggtcttacc actgctttcc
     9961 atgtatctgg atagtttatt tatcattata tctgtgtgtg agtttaattt ttcttttaga
    10021 tttttatatt cttctttgct taaccttaca tttttgaatt ctccataaaa aatgggggtg
    10081 gactttttat ctatctctcc ctctctctct ttatctatct ctatatcttt ccatgtaatt
    10141 ccaatctgga gtacctctac tgtctatcgg taatttaatt ttgatatctg gcaatactgt
    10201 gctagatatt tgatctttat attcagtatt ttttaaagct tgcctaataa ttgaagttaa
    10261 atagaatgct acttctttat tcaattcttt attttttaat tttaaacaat gaattttcat
    10321 atctaggctt gctttatatt tatgataaaa gactgctcct aaaaatgaaa cagatataaa
    10381 attttcaaaa actctataat ttttatcatc tatatcttcg tagtaaccta agataccatt
    10441 gtcaatattt gtagcactaa ttctaggagt ttttccatcg agtaaatatc tttttggaat
    10501 agatgagcct gttggtactt gactcgattt cccctttttt tcggtaataa atatttcttt
    10561 ttattttgtt gtccgatatt tttcctacct gtcctttgta ggatgagtat tttctagatt
    10621 ttcttgaata actttttact tgaagtttta gcttttgaac tagtcgttgt actttctttt
    10681 tgtttattat cagtcctgat ctttttaata ttgctgttat tctctatatc ctatttttca
    10741 ttcatgatat tcttttacta attttatctt aaattctgtg ctgtatttgc cattaaaaaa
    10801 ctgacctcct ttagttagtt ttttggccta acttttgagg gtcagttcaa aatttgcgac
    10861 ttttaaatga attccgatat tcaattatta agagctaaca tggtgcttgc caataggaat
    10921 cattagaggc gaattggaaa tagggtcacg tataattttt gcttcaagat taaagatatc
    10981 tttaactagt ttatcattta gtatatcttc aggctttccc tctgcaacaa gtttaccttc
    11041 tttaattgca aataggtaat cagcgtatct tgctgttaga tttatatcgt gcaaaatcat
    11101 gcaaatggtt gtcttatatt tttggtttag atcagtcaag aggtctaata gttctatttg
    11161 atatgagata tccaagtaag tagttggctc atctaaaagt aggatacttg tatcttgggc
    11221 tagggctaga gctatccata ctctttgcct ttgaccccca gaaagttctt caactaggtt
    11281 atttgctaga tcttcaacat tggccttaac cattgatctg tttattattt caaggtcatc
    11341 ttttccaaga ctcttaaaag gctttctgta ggggaaacga ccacggctta caagatcagc
    11401 tactgttatt gattcaggga ttattggaga ttgaggtaat atagctatgt gttttgctaa
    11461 atctttttct ttataagaat taattgattt attatcgagc aatacttctc cctctaatgg
    11521 ctttataagt cgagacaagg ttttaatgag tgttgatttc ccacaaccat ttgacccaat
    11581 aataactgat attttttctt caggtatttt tatatttata ttttccaaga ttattttttc
    11641 atcataaccg caggtaagat tatttgacca cagacctttc attatatatt cctcctgttc
    11701 atttttatta gtaagtatat taagtatggt gaacctaaca agccagttac aacacctact
    11761 ggatatctag ctggtaaaat attttgagag aatatgtctg ataacaaaac tagtaaaatt
    11821 ccaaccaatc cagctaatat tgggcttctt ttcttgccaa tatttaaggc tatgggacca
    11881 gctaaaaaag atatacaagc tattggtcct gtaattgaag tagaaaaagc agttaaagat
    11941 acagcgcaaa aaattaaaac aagccttgaa agctcgggat ttgctccaag tccgattgct
    12001 atttcttcac caagttcaat aatttctagt cttttattaa aaaataaaac taatatagta
    12061 gcaataatac ttactattag aacaagaggt atgtcatcta actttgtaaa agataaagag
    12121 ccactgagcc atctcataac ttcttgtaat tcatatcttg ctactttcaa caataaaaat
    12181 gaggtgcctg ctcttgtgac agcttgaaaa ccaatgccta atattatcag tcttgctgct
    12241 gaaaaaccat cttttttagc tagtaaaaat aatattaaag atgatgttag tccacaagtt
    12301 attgaaataa ttccagtagt taaactattt gtttttaata ccaatatgca aaagaccgct
    12361 gcaatagatg aagaacttgt gacaccgatt atatcaggac ttgcaagagg atttcttaac
    12421 atagtttgaa agataaatcc tgccaatcca aaagaccagc cagctataat tcctgctaat
    12481 aattttggta atctaatttc cataatcgaa aaactagctc caggaacagt ttcactattt
    12541 aagactttaa tcaaagttga aaaagaataa ctttcatctc cgataagtaa aatgaaaaat
    12601 gatagactga ttattattaa taaaaatagt gaggaaaata gtgttattct attttttctt
    12661 ttttgaatac ctataattaa attttgcatt agttattaac ccctctattt ttcatagtta
    12721 cataaataag tactggaccc ccgattattg cagtaattat ccctacttca atttcacctg
    12781 gtttacctaa catacggccg attatatcac atataagcaa gagctctgca cctataaaag
    12841 atgaagaaat ggtcattgtg cgtatatctt tgcttataaa taagccacaa aagtgaggaa
    12901 ctataagacc tacgaagcca ataggtccac caattgcagt aatacttgaa cataaaagca
    12961 cacttgcaat tattgcaagt gatcttatcc tattaacatt aactccaaga ccaacagcca
    13021 tttcatcacc catagctaaa gcgtttaaat ctgatgaaat aaatatagct atcaaatgac
    13081 ctaaaattat aaaaggtagt agtgtagata tagaagataa tgtagctgct ccaaggctac
    13141 ctatttgcca aaatctaaat ttgtctaaga cgttattatt cggtaaaatt aaaaaactta
    13201 caaaactgct taaagccata ctaacacaag ttcctgataa ggcaagtttt ataggggtaa
    13261 ggcctgcttt tccgcttaca gcaatcgcgt atacaaaaat tgcacttact aagccaccaa
    13321 tgattgcaaa acttatatgg cttatgcttg atgaaattcc taaaaaagaa agaccaatta
    13381 ctacactaag acttgctcct gtgtttatac cgagtatacc tggatcagct attgggtttc
    13441 tagtaactga ttgcatcaat acaccgctta tggcaagact agaacctgct aaaattgcaa
    13501 aaatagttct aggtattctt ttatatataa ttgatttaat aaaatcatca tttgtattac
    13561 ccattccaaa agctgctaaa aaatctctga tattaatttc ttttgttcca agctttaatg
    13621 acaaaaatat tgtaataaga agacctaggc agattacaaa aattatgcct aggtttattt
    13681 gttttttatt tcgcattttt gcatgcattt cctaaaagat ttaggtattc ttcaatagta
    13741 tagtttattg aaagtggtgt tggagtgcat gaggctgcta acggtgtatt atctggaatt
    13801 acagcaacgg caccattttt aattgcattt attttaccta aaagaggatc tttttgtaaa
    13861 gcttcaagag ttttatcatc accataagtt atgattacat cagcatcatt tatcttattt
    13921 gcttcttctg cagaaatttc ctttgcaaaa ctatcttcac tctcaaattc ttttaatgat
    13981 tcagggaaaa ctagacctaa atctgttaaa taatttgctc ttggatcttt gctagtataa
    14041 atccagaatt ttgatgtatc tgcagcatta atcatagtaa ataatacttt ttttcctttg
    14101 atttttcctt tgatttctgg atgtttttct aattctttgg atatacgagc ttcagtattt
    14161 ttgattaact catcaccttc tttttccata cctaaggctt ttgaatcaat tttaatcata
    14221 tctctccata aagtttgcca aggtttagat ttgtatgctg ctacaggagc aatttttgat
    14281 agagtgtcat aatcttcttt agttatacca gaataacctg ctaagataac atctggttta
    14341 gaatttgata ttgcttcaaa gttaagtcca tccaaatcgt caaataggtt agctttacca
    14401 tttagttctt tgattttttc ttctgtccat ggtaaaactc ctttatcagc acttacaccg
    14461 taatttgctt ttgaaaatcc aacaggaact attcctaaag ctaatgctac atcatgattt
    14521 ccccaagcaa tagttgcaac tctttcaggt tttttatcta atatagtttg accgaaagca
    14581 tgatctaaaa ctattttatc aggcgcatgc tctttagaag tattttcttc atttttaaca
    14641 gaattagaag aacaagcgct aaaaactata cacatagcta aaatagctat tagaaaaaat
    14701 ttgtttttca taaaaactcc ttaaacatat ttcaagtcta ttgtatcgat aataattatc
    14761 attgtcaata gatacagtta caaatttaat aatataattt tttcaaaaaa ggatctagtt
    14821 tttattttta gttaaattat gtctatattt ttcattaact catcaataaa aatttgtttg
    14881 ctaatatctc tttcttctga ttttgtttca aggattattg ctacatcatt catattttta
    14941 ggtaaatacc aaccatctgg cttatctgaa tatcccttga agcctaattg attaaaagta
    15001 gttatttgac cagtaccttg attgatgttt tcttcaactt cattaaagcc tatacttctc
    15061 ttgcataatc cctaacttga tcttctgtcc ttaaagtcat tttctattcc tcgtcactaa
    15121 aattatcttc aaaactaata atatcattag gagtgcaaga taaagcctta catattcttt
    15181 ctaaattctt aaatgtaatt ggtttatcct ttcccatttg tgccataaca tttgttgtaa
    15241 gtcctgccat agctattaca tctgttttct ttagtccttt ttttgctaac tgtatccata
    15301 atggtttata gttaagtgcc ataatatccc tctttttttc ttcattagat ttatttaatt
    15361 atagcataaa tattgatttt attcaatctt acattgattt agtgatttgt tttagagaat
    15421 ttgttgtgtt attccgtcct tattttgcca taaattgttt taagtgggac ctcttatcct
    15481 taccattttt acctcctaat tttgagtata aaaaagacga tagagttttt aatttctatc
    15541 gtctgagatt tacatattaa attttcatca caaaataaga ctctttaaag aatctttaaa
    15601 ttcattggta tgctgcttac aatatccatt attaaaatgg atattgtaag cagcatacca
    15661 actatttatt ttttgagttt taaactttgg tagaagtctt gaactcctta tatttacata
    15721 actatttgcc tctataactg ttatgacacg aaaccaacaa gcaagttcaa gcacctccat
    15781 atctttattc aaatgaggac taagatattc acaaacttta tcataaacct ctttatcttt
    15841 tttcataaaa ggggcataca acttagcaaa tttatcctaa aattttttgt tgcctttatc
    15901 aatcatttca acgctccttt aaatataaaa atgatcctat caatctttat attgagccta
    15961 ttttctaatt gataccttgc aagaaaggaa taatagctgt tcctatacca agtaggaatg
    16021 taataaatgc agaaagtcat atactgtcat tcttttctat taaatcattt tgaagtgtct
    16081 caaagcatcc atgatggctt cttctttttc aggtgtacac tgtggaataa tttgtttatc
    16141 ctttttagac ttgttgtaat gttctcgtaa ttctattcca catttctttt ttatctgtgc
    16201 aatatataat gtcgaaactt ttaattcaaa tttattccaa acatattctt tgatttgagc
    16261 atatgttgct ttgctctccg cacttgtcaa atccatctca tccagctcaa tttcaacact
    16321 tatgtgctta tcgacatcaa gtttggacaa aagtgctacc gtctcgacgt gatgcgtttg
    16381 aggaaataga tccaccggct ggactttctt caattcatat cccaattctt ggtagagttt
    16441 gatatcacgc gccatggttg cgacattgca ggagatatag gcgatgcgat cggctcctgt
    16501 ttgggcgctt gctttgataa agctttctgt caagcccttg cgtggaggat caaccaagat
    16561 aacggttggt tgaatcccat ctttaagcca attcttcata gcattttcag ctgtgtcaca
    16621 gacatagtgg gcgtttgaaa tattgttcag ctgagcattt tttttactat tctcaaccgc
    16681 ttctggaatc agttcaacac cgtagacttc tttgacatgc ttggcgactg ataaaccaat
    16741 ggttccaata ccagaataag catcaataac cacgtcatct ttttttaact ctgcaaagtc
    16801 aatggctgtt tgatagagtt tctccgccat ttcagtattg acttggtaaa aggctgggcc
    16861 agcgatttgg aagtcatttc ccaacatctg gtccgtaata tagtcttgac cataaagagt
    16921 gcgccactcc ttaccaaaaa tcgcattggt attctggtcg ttgatatttt gcatgacaga
    16981 cacaatctct gggaactgct tgataacttg ttcaatcaat tggtcaacac gaaaaacttt
    17041 tggacgagtt gtcaccaaaa cgaccatgat ttgtcctgaa tagtgaccac gacgcaccac
    17101 aagattccga atcaatccag actgttcctt ttcgtcataa ggttttaaat caaaacgacg
    17161 gagcaggcct cgaagagcta ctacgacttg gtcaatgaca ggatcctgga taaagaaatc
    17221 ttcaaggggc atgaggtcgt gcgaattctt acggaaaaat cctgtttcca agacaccatt
    17281 cactcgacga acgggcacct gcgccttatt gcgatacttg actggatgtt ccataccaag
    17341 cgtttcagca acttctacat ctgcaattcc agcaatcttg tagagactgt ccttgacttg
    17401 cttggtttta aacttgagct gttctggata agaaaggtgt cctaaatccg cgattcctga
    17461 acgcaggtaa gccaaatcta gatcttgatt acggtgtggt gactggacaa ggtatttttc
    17521 aacttttcca aagccaatct ttttattgac cttgaggaca cgcatgagaa ttttttcact
    17581 cggtaaagca ttctctacaa aaaagaccaa accatctacc ttggcaactc ctgccccttc
    17641 atgggtcaag tcaacaattt caacttctac aatatcattt ttctttaaca ttcttttctc
    17701 tttctattgg ccgacaaaaa agacggtaac gttacggtta ccatccatta taccatgaaa
    17761 tttcttaaga accaaaactc ttgaagaagt tgacaagggc ttgccagagg gagcttaaga
    17821 agttaccacc gtcctctagc gccttatccg catcaaagtt aaggttgata tttttaaaac
    17881 tgtcgccagc ttgtgatacg atgctttgtt taaggtcatt tagggtttta gtgaaatctg
    17941 cattgctgag gatatcactc tttgagagat tcaaggcaaa attgatgatg atattgatct
    18001 ggtttcctgt tatgacctga tcaagtttgt aattttttaa ggtatcttca acaatcttgc
    18061 ggatatcttc ttctgtcaga tttcccttgc tttctttagc tttggcgagt cctgacttga
    18121 tatcagctag ggcaacgttt aatttattag catcatagcc tgatttgtcc ttgttttcag
    18181 cattgatatc tgacaaagct tttagctctt cttgagccaa atctttatta gcttgtggca
    18241 ccttggctcc attagcctct agcgaatagt aaatccctgc taaagcactt tctcctgtaa
    18301 ctggaatagg ggctgctaca gtgattttgg catgttccat acccagcgtt actgctgcgt
    18361 ttcggtacat atcctgagtc accttagtga tattttctgg tgtttcaatc ttgacctcaa
    18421 gtggcgattt gtcacctagc ttttgaatct tggctgatga atacaactgt aagctagagt
    18481 cattggccac attcatgatt ttagaataaa catcaggtgt catggtcttg agttctttgg
    18541 tatctgttga ggcattgtag cccagttttt taagagtttg atttttttgg tcttcagata
    18601 gggaggaacc taggacatat tcaggttgga cataggtttc atcgataact ttttgaacat
    18661 ctgttgctgc atggacgcta ttcatagctg ttactgccca caagaccgca gcactagtca
    18721 gaaagagttt ctttctcata gggaatttcc tcctttactt ctttatagta atatatctat
    18781 cttaaagaaa acttataaca aaaacacctg gtctagccag atgttgaaaa gagagtgaaa
    18841 catttgatga tgtaaaggtt aagtcgtacc tgtctagaat aataataatt tcctccattt
    18901 acatagagtt cagcaccgtg aaaaatggaa atggggtgaa tataactata agtctttcca
    18961 gtcgtattac caagcaaggg ggcaacagtc tcacgagagt actgtttggc tagagccaag
    19021 gtattttcct tgccattttg ggcgataaaa tcgatatagg caggtccaaa attataggct
    19081 tgaacagctg tccagatatc tacacccttc ttctgcgcca gatagagatt gcctgtcaga
    19141 gtttgaatgc cttgccgaat gctagaggca ttatcattga tggtgttggt ggaaccactt
    19201 gcagactcac tagactgcat aacatcgcct tcttttcctt ttgtttcagt ataaatcata
    19261 gcaagcacaa gctcttcgtt tgctggggtg tctttttcac tcaagatttc tcgcaccatg
    19321 ggttgatagg tcatgacttg tttgacatct tgatgaacgc ggtaagcttt atagccagca
    19381 aaaaggaaga ctgctagtac aagcactctt cgaattcgtt taaacattat ttactttgga
    19441 tatcctcgat atttttgatt aagatagagt aggttccatt ttcgttttgg ataaactcaa
    19501 cagactcggc gtcttgatag acgttattgg gaacgatgag ctcaattcca tttgataagg
    19561 agagtttttg gttttcaaat ttctttaatt ggcgacttgc atcaatttca tcaaattgaa
    19621 caggttctgg tacggcttct ttgacttggt caataaagct caaacgagcc gtcagattgt
    19681 tgtcaaaaag gtcattagcc aatttctcag gtgacaattc attgctttct tctaggttgt
    19741 tgaaaatcgc tgatttgacc ttggattgaa attgaaaatc atctgtgtta aaagattcag
    19801 caattctctg ggctgttttt tccagttcct tgatagattt tttaggagaa atcttaggag
    19861 cgacagcaag aagattatct gaaaaatagt tcaaaaaagt cccgttgtac ttgattcgtt
    19921 tttcaatcag gtgatacttg cgactctgaa gattgaccac caaggcctcg tcagcacccg
    19981 ttccaaatcc aggcaggtta ttctgagtca gcttgattgg attatcaact tctcctccga
    20041 ggtgggtcaa ggtctcccgc agggcaattc gcaagaaagc gaaatgttct acaccttctt
    20101 tagaaaattg aacaaaaatc aagtcattgg tcttgagatt ttcagaaatg ctaaactcct
    20161 ctttccagag attagccagc gttactgatg tctccaacaa atcgtctgta atatgattga
    20221 agaagggatt ttcttcttcg aaaatcccag tcttggcttc atctgaatac acatgttcaa
    20281 tttttttacg taggtattct tcgatttttg gagtaatatt gagaaactta tctgctaaga
    20341 acagctcggt atcatccgga ctgaactggt gaataatggc tttcttaata taaatgtcca
    20401 taaaagtttt attcctcgta taatgggaag gcatctgtca attctttgac tgcacttctc
    20461 acttcttcta atacagcctc attttctgaa ttcttaaggg ttttaatgat gagttcagcc
    20521 actttgcgac tttcttcttc accaaatcca cgtgcagtaa tagctgctgc tccgatacga
    20581 atcccacttg tcttgaatgg tgacaaggtt tcgtaaggga ttgaattttt atttagggta
    20641 atattgactt catccagcaa gttttgagca acttttccgt tttctacaac cttagtcaca
    20701 tcaacaagga agagatggtt ttcagttcca cctgaaataa tacggaaatc agggtcttgc
    20761 aagaagacat ctgccatagc cttgctgttc ttaattacat tggcagcata ttccttgaaa
    20821 gctggatcca aaacttcttt gaaggaaact gccttagcag ccacaacatg ctccaaagga
    20881 ccaccctgaa taccagggaa aatagctgaa ttgattttct tagctaaatc ctcatcattg
    20941 gtcaaaatca aaccaccacg aggaccacga agggttttgt gggtcgttgt tgtagtgata
    21001 tgagcgtatg gcactgggct tgggtgaaga ccagctgcaa ccaagccagc gatgtgggcc
    21061 atatcaacca taagcttagc cccaacagca tctgcaattt cacggaattt tgaaaagtca
    21121 ataatttgag aataggctga agcaccagct acaatcagtt ttagttttac ttcttgggct
    21181 tgtttcaaga tagcatcaaa gtccaaaagt tccgtttcag gatccacact ataggaaaga
    21241 aagttgtagg tttgaccaga gaagctaact ggagctccgt gggtcaagtg tccacctgct
    21301 gccaaatcca ttcccataac cgtatcacct ggctcaatca aggacatgta agccgcacag
    21361 ttagcttggc ttcctgaatg tggttggaca ttggcaaatt tagcaccgaa aatttctttt
    21421 gcgcgttcaa tagcaagagt ctctacaacg tctactacat cagttccacc ataataacgg
    21481 cgtcctgggt aaccctcggc atatttattt gtcaagatag acccttgagc tgccataaca
    21541 gccttggaaa ctacgttttc cgaagcaatt aactcgatat tattttgttg gcgttcttct
    21601 tctttggcaa tagcattcca gagatcagca tcatatgctt taaaatcatc tttgtcaaaa
    21661 atcataggtc ttctccttta ttgtgtgact agtccattag tttgatttta caataagaaa
    21721 atcaaactaa aagatgcgaa taaaccgttt ctgcatttta tcacaagtat agccaacttt
    21781 ttcataaaat gcatgagcac ccagacgatg attggcagaa tttaagcgga taaacccata
    21841 accacatctt ttggcttctt gttccaaccc ttgtagtaaa cttttaccga taccttgacc
    21901 ttgcgcttga ggtgaaactg ctaaagctaa gatattaaat cctgctttgg aatagagtga
    21961 ttcgtaaact tcagcgtgga catatccaag taagacatga ttagctgcat cctcatagcc
    22021 aagtaggaaa tgatgggaat cctgagacag tctagctagt tggctagccg tttcctctgg
    22081 actaaaagta taacccaaag cctcttggtt gatgtcacat atcgctttca catctgtttc
    22141 ttgcaaatct cttagcattt caagcctcct caaaagaaat ctctggcaac cgagcaagaa
    22201 tatcttctcg tttaattgcg ccttggcgta agattttcac cttgtctcca gacaaatcca
    22261 caatagttga atcctgtcca gttagaaaag catcgtcttc cagacccaga acctcttggt
    22321 caaaatcctt cagaatttgt tcaaaggtta caccacttgc ctgacctgag atattggcag
    22381 acggcccaat caagggacct gtctctcgaa ttaaatccag tgtgataggg tgactgggca
    22441 tccgaaatcc aatagttgca aggtcagaat ttacccaata gggaactcgg tcattggctt
    22501 cgagaataat ggtcaaggga cctggcaaaa aggtctctac aagtttttgt agataagctg
    22561 gctgattctt agaaaagtgc aagatatcct ctaaagaggc aacattgaga ttgagcgcct
    22621 tgtctctagg acgacgtttg agctggtaaa catggtcaac tgctttttcg tctaaggcct
    22681 tggcaaaaag accataaacc gtctctgtag gcagaatgac agctccacca ttttccaact
    22741 cttgtctaat cctgtccatc atcaaccacg accatcctat cttgaccaaa ttggtccttg
    22801 agtgttcgaa ctcttttttc aggaagatgt ttcctaaaaa gttcgggaac actttgacct
    22861 tgcttgtatc caatttcaag gtaaatctta ccaccatcct tgagatagtc ttttgcatct
    22921 tccgcaattc tacagtaaat agctaggcca tcctcgtctg caaagagagc tagatgaggc
    22981 tccgaatgca aaacattcaa gcctacctct gactcatctt cacgagagat atagggtgga
    23041 ttggatacaa ttatatcata tttttcagaa atttctgcaa aacaatcaga ttttttaaaa
    23101 aatatattaa gattttgatc gctagcattc tctgatgcaa gctctaaggc ctcttgagaa
    23161 acatctgctg ctgtcactga ccaatctggt ctattttttg ctagagcgag agcaatagct
    23221 ccactacctg ttccaatatc cagaactgag agattcgtct caagattttc agttagaata
    23281 agctccacta actcctctgt ttctggacga ggaatcaaaa cccgttcatc cacctttaaa
    23341 tgcattccat aaaaatctgc ctgtccaatg atgtactgag ctggcttgtg agctgctagt
    23401 tgctggtaaa tatcttctac aaattgtttt tcttcctctg ttgtcacctc ctgctggagg
    23461 gcaaaaataa agtctgtaaa agatagattt ttcagactac gatagacaaa agagaggctt
    23521 tccgcttcct ctccttgtct tatcaactct tcttcaaaat ttgaaaataa ttgagctaat
    23581 ttcattattt gtttaattct tctagttttt gtgtttggtc ataaagcacc aaggcatcca
    23641 caacttcgtc caatttacca gacaaaatcg tatctagttt ttggagggtc aagccgatac
    23701 ggtggtctgt gacacggttt tgtgggaagt tataagttcg gatccgttct gaacggtcac
    23761 cagtaccgat tgtcgactta cgctcagcgt cttgttcatc ctgagcaatc tgagcaaagt
    23821 ggtcagcgac gcgtgcacgg ataatcttca tagccttctc gcggttcttc tgctgggtac
    23881 gttcttcctg catctcaacc ttgatattgg ttggcaagtg aacgatacga acggcagtcg
    23941 caaccttatt gacgttctgt ccaccagcac cagaggcgtg atagatgtcg acacgaaggt
    24001 cttttggatc aatgtcgtat tcaacctctt caacttctgg cataacaaga actgtcgctg
    24061 tcgaagtatg aacacggcct tggctttctg tcacaggaac acgttgcaca cggtgggcac
    24121 ctgattcata cttaagctta gagtatacag actgacctga aaccatagca accacttctt
    24181 taaaaccacc gacaccattc atagaggctt ccatgacttc aaagcgccaa ccttgggctt
    24241 ccgcatactt ttggtacata gttagcaaat ctccagcgaa aagtgccgct tcgtctccac
    24301 cagctgctcc acggatttca aggatgatat tcttgtcatc gtttggatcc tttggaagga
    24361 gcaaaatttt cagtttttct tcatattctt ctttttcagc cttggcatct ttgagttctt
    24421 gcttggccat ttcttccaag tccgcatctc cgcctgattc cttaatcatc tcttcggcat
    24481 cgacgatatt ttgaaggact tgtttatact cacggtaggc tattacggtg tcacgattgg
    24541 aagcttcttc ttttgaaagc tccataaaac gcttggtgtc tgaaacgaca tcagggtcac
    24601 tcagcaattc tcctagttct tcataacggt cttctacagc ttgtagttga tcatagatgt
    24661 tcattttttc tccttatttc tcaattgtta aatcatagat tgctactact tcattctcgg
    24721 ctatttcccc agtttcttta aatccataac tgaggtaaca aaatcttgcc tgttcatttt
    24781 ctggttcata agacaaccaa agtttattgc ttaaacctgc tggcgctgtt cgaacatagt
    24841 ctagtacttt atccataatt ggtttaaaat atccttgatt ttgaaaattc ctatcaatca
    24901 taaaacgaaa tagtaaataa tttccactac taattccgat ctttttatca taagctatca
    24961 tcacaaaacc tataattgca tcattatcat aaactgccaa tgtagctaca aaatctccat
    25021 ttttagtgta gacgtatgct tcagctaaac taattgcgtt ggttgcaatg aattgttttt
    25081 gatattcctt gacatccaaa tttaaaacat caaaataatt ttccattgta acatctctta
    25141 gttcaattgt catagttttg ctccttgtta gaggttatca ttggcgtaaa ataatgttta
    25201 cggcaaactg agatataggt ttcgttacca ccaatctgga tctgttctcc atcgtaaacg
    25261 ggcagtccat cctgtgttcg caacaccatg gtcgcctttt tcttgcaata ctgacagatg
    25321 gtcttgattt cgtcaatctt gtctgctaaa agcaagagat atttggaacc ttcgaacaat
    25381 tcattgcgaa agtcattttt caagccaaaa gccatgacgg gtatgtctaa ctcgtccaca
    25441 acacgagcta ggtcgtaaac atggtggcgt ttaagaaact gggcttcatc gaccaaaaca
    25501 cagtaaggtt tttctggtag gtctcggata tagccaaaga tatccgttgt ttcctcaatc
    25561 gcaagggcag ggcgtttcat gccaattcga ctcgacacat agccaacacc gtcacgcgta
    25621 tccagagccg aggtcataat gacaacacct tttccttgct cctcgtagtt ataggccact
    25681 ttgagaatct caatcgtttt accagagttc atggtcccat aacgatagta caactgtgcc
    25741 atgtttcttg cttcacgtcc atttctaaat ttttgctaca ttctagtata tcataatttt
    25801 cttaagcttt aaacggcaaa atgtggtaaa atggaagaaa tcaaaactag tggaggaagc
    25861 tattatgcca tttgtacgca tcgatttatt tgaaggacgc acgctcgagc aaaagaaagc
    25921 tcttgctaag gaagtaacgg aagcagttgt ccgcaacact ggagcccctc aatctgctgt
    25981 ccatgtcatc atcaacgaca tgccagaagg aacttacttc ccacaagggg aaatgcgtac
    26041 taaataagct agcttaagca gaattgctta ggctttttca atctccaagt agcattcatt
    26101 gaagaaatat cctaaatttg ttacaatttg aaaagaaact tggagaattt ccaagaaaag
    26161 agctattaat taaaggaaac attatgatta cacgtgaatt tgataccatc gctgctatct
    26221 ctactccact aggtgaaggg gctattggta ttgtccgcct gagcggaaca gacagttttg
    26281 ctattgcgca aaagattttt aaaggaaaag acttgaacaa ggttgccagc cacactctca
    26341 actacggtca cattattgat cctctgactg gtaaagtcat ggacgaggtt atggttgggg
    26401 ctatgaagtc tccaaagacc ttcactcgtg aggatattat cgagattaac acccacggtg
    26461 ggattgcggt gaccaatgaa attctccagc tagctattcg tgaaggggct cggttggcag
    26521 aacctggtga atttaccaaa cgtgcttttt taaacggtcg cgtagacttg acacaggcag
    26581 aggctgtgat ggatatcatc cgtgccaaga ctgacaaggc catgaacatt gcggtcaaac
    26641 aattagacgg ctccctttct gacctcatta acaatacccg tcaagaaatc ctcaatacac
    26701 ttgcccaagt tgaggtcaat atcgactatc ctgaatatga tgatgttgag gaagctacta
    26761 ctgccgttgt ccgtgagaag actatggagt ttgagcaatt gctaaccaat cttcttagaa
    26821 cagcccgtcg cggcaaaatc cttcgtgaag gaatttcaac agctatcatc ggacgtccca
    26881 acgttgggaa atccagcctt ctcaacaacc tcttgcgtga ggacaaggct atcgtaacag
    26941 atatcgctgg gacaacacga gatgtcatcg aagagtacgt caacatcaat ggtgtacctc
    27001 tcaaattgat tgatacagcc ggtattcgtg aaacagatga catagtggaa caaatcggtg
    27061 ttgagcgttc gaaaaaagcc ctcaaggaag ccgacttggt tctactagtg ctaaatgcca
    27121 gtgaaccact gactgcgcaa gacagacaac ttcttgaaat tagccaagat accaatcgca
    27181 ttattctact taataaaacc gacctgccag aaacgattga aacttcgaaa ctacctgaag
    27241 acgttatccg tatttcagtc cttaaaaacc aaaacatcga caagattgaa gagcgaatca
    27301 acaacctctt ctttgaaaat gctggcttgg tcgagcaaga tgctacttac ttgtcaaacg
    27361 cccgtcacat ttccctgatt gaaaaagcag ttgaaagcct acaagccgtt aatcaaggtc
    27421 ttgagctggg gatgccagtt gatttgcttc aagttgactt gactcgtact tgggaaatcc
    27481 tcggagaaat cactggggat gctgctccag atgaactcat cacccaactc tttagccaat
    27541 tctgtttagg aaaataagaa aaatccatga tccttcattc ggtcatggat tttattgtct
    27601 ttattagtaa tctggtctta agacccctgt tacagttgcc ttagttgctt cgtagtcgcc
    27661 atctacgaca accttgataa tgcgtttggc atcttcttct ggtgctggaa caagaggtag
    27721 acgagtgggt ccagcttcaa atcccatata gttaagaatt gccttaactg gagcaggact
    27781 tggataagag aagagagcat taaccttagg aatgaattta cgctgaattg ctgcggcttt
    27841 cttcatatcg ctttctgcaa tggcagtaaa catctcgtgc atttcatccc catttgtatg
    27901 agaggcaaca gaaataaccc catccgcccc aaggttcatg gcatggaaag catctccatc
    27961 ctcacctgta taaatcaaga actcttcagg cttgtgctca atcaagtaag ccatattagc
    28021 caagctagta cattctttga caccgataat atttggatgg tcagccaagc gaagcatggt
    28081 ttctggagtc aattcgacaa ctacacgccc tggaatgtta tagataataa ttggtaggtc
    28141 agaagcatct gcaatagtct taaagtgctg atacatccct tcttgagaag gtttgttgta
    28201 gtaaggaaca atagcaagcc cagctgcgaa accaccaaat tccgctactt ctttgacaaa
    28261 ctcaatagag tcacgcgtat cattagtacc tacacccgca atcaaaggaa cgcgtccatt
    28321 gacaaccttt tgtacagccg caaacaactc caactcctca tcgtgggtca aagttggact
    28381 ctcagcagtc gttcctgcga gaagaattcc atccgtatga tgggccaata aatgctcaat
    28441 caaggctgga atagcatcaa agttaatgga accatcctca tggaaggggg taataaaggc
    28501 tgtaatgatt ttacattctt ttaaatcttg ataagacacg aaaacacctc tctatttcaa
    28561 agaaggagtt catctgaact cctaaacgat atgactattt taattcaaat ttcaattcgg
    28621 ctgttggacg aaccaatcca cgttcatgaa gagtttcagc aatctgaact gagttccaag
    28681 cagcaccttt gagaaggtta tctgaaacaa cccacatgtg aattcctttt tctgcatcca
    28741 agtctttacg gatacgacca acaaaggtat cacgcgaacc aactgcattg atagcttgag
    28801 gatagatttg atgagctaca tcatcttcaa gaacagcacc tgggaaggct gcgatagctg
    28861 cttttacttc ttcgattgga gccacttctt ttgtttcgat ataaacagac tcagagtgag
    28921 ctgacaagac tggaatacgc acacatgttg cagatactgc aatgctatca tcttccataa
    28981 ttttcttagt ttccttggtc atcttcatct cttcgtacgt gtaatcatta tcagtgaaaa
    29041 catcaatttg tggaagagcg ttaaaggcga taggataatg tttcttgtca ccacctgaag
    29101 gcaagatttc cgcatgcaaa tcacgtggtt tcacaccatc attcaaaacc tcacgaagtt
    29161 cacgttgtgt ctcaagaatt gctcccatac cagcacctga aacggcttga taagttgaaa
    29221 caatgatacg gtccaagccc catttttggc gaaccggctc aagagccacc atcatttgga
    29281 ttgttgaaca attagggcag gcaatgattc cgttgtgagc atcaagtgca tgagcattga
    29341 cctctggaac aaccaaagga acatctggat tttgacggaa ataagatgta ttatctacta
    29401 ctaccacgcc agcttttact gcgtatggtg catacttagc tgatgtagaa ctacctgctg
    29461 aaaagagagc aatatcaact ccttcaaaag ctgtttcagt cgtttcttca attgtaatat
    29521 cttgatcttt aaatttcaat gacttacctg ctgaacgtgc agaagcaagg taacgaattt
    29581 tatcgattgg aagtgttgat tcttccaaca tttttatcat ctgagcaccg acagcacctg
    29641 tcgcgccgac tacagcaact gtatatccca taaataacct ctttcggaat tttctaaaaa
    29701 tttctataat agaagtatta tactactttt tccatgaatt gcaaagcttt ttcatcattt
    29761 tttggaaaat aaaaatccca gtcgctagac tagggactaa gaggcatctt catgtgatga
    29821 gcaggttcac acaactcatc aaggtccgct cctgcgttat gacctcctta tgctcaatag
    29881 tagtccgaag actacctatc gactcatcgc atattctata ttactagaga tacttgattt
    29941 tgtcaataag aaattttttc gatcgagtat aacaaaaaac tctcgtattc aagagtttcc
    30001 ctatacatat catgctaatt gccgggattg aaccggcgac ctcatcctta ccatggatgc
    30061 gctctgccaa ctgagctaaa tcagcttact taagaagtat actatattca gaaaaacttg
    30121 tcaagtttcc ttagaaattt tccataggaa aaagccaggt aagaactacc tagcttatct
    30181 tcttctattt acttaaatca attcgacgac caattttacc aataataatc gccccaataa
    30241 tcaatgaagc aaattcaccg attcctgttg taaaccaagt aaggaagaat ggtaattctg
    30301 ctacaatatt taactctgca gcgatagtaa acatggaaat tgaaaagagg attgaaaaga
    30361 agaaatgatc ttttcgaatc aatccgttaa agaggtaatc cttgctatat tttgcaaaaa
    30421 gccaaacacc taaactgagg aatactaagg ttgaaccacc accaacaaag acatctagca
    30481 gtccgaagct aaagaaatta gcaatcatac aaccgatggt aactccgatg atgtacttag
    30541 gattgtaaaa agccataaag ttcatcattt ctgaaatacg aaactgataa gcaccatagc
    30601 tgatggcatt taggggcggt gtgacagtca aaacgacgta gatagcagcg acgattgcaa
    30661 tatctgcaac atcacgaata gttaattttt tcatcttttc tcctttggcg gttgcccgcg
    30721 tgtaatatgc ttggtgaaag aagctaagca ccaagggttg ctttattcaa ccctactagt
    30781 atagcacaat agcctgcttt atgctatact taacacatga aaattcctat tcaaaaattt
    30841 tttaacaatg aaatcttagc ctatctcttt tttggccttg cgacaactct agtttcgatt
    30901 ctctcacgac tagtcattta tcaactaagt catcaggaac tcctggctac tgccctagca
    30961 aatattatcg gtatcctatt tgcctttatc acaaatgata cgattgtatt taagcaaaaa
    31021 aagaaaaata gacttatccg tttagtgaaa ttttctcttg ctcgcctttc tacttttctg
    31081 ttagacttgt ttttaacttt tctctttgta acccaatttc ctcacattat agggcaattc
    31141 gtaactgaaa acattgataa gataaatgct attgaaacaa taattgcaca aatattcatt
    31201 attatcatca attatatctt gagcaaggcc tatattttta gaaaataatg ctccatttat
    31261 gagcctttta attgccttct ataatgattt aggatacaat gaaacacgaa acattgaaag
    31321 gaaaacagta tgttaaaaaa tctaaaatcg ttcttgcttc gaggaaatgt tattgacctt
    31381 gctgtcggtg ttgtaattgc ctctgctttt ggtgctatcg ttacttcact tgtaaacgac
    31441 attatcactc ctcttatttt aaatcccgct ttgaaagctg ctaaagttga acgtatcgct
    31501 caactttctt ggcatggagt cggctatggt aacttcttaa gtgctattat caattttatc
    31561 tttgtgggta ccgccctctt ctttattatc aagggcattg aaaaagcaca gaaactgact
    31621 ggcataaaga aagaaaaaac tgccgaaaaa aaaccaaccg aattggaagt ccttcaagaa
    31681 ataaaagctc tccttgagaa aaaataatcg attaaaagga tctagcgcaa agctaaatcc
    31741 ttttttcttt actctttggg taacttgcct gctttttcaa gcattttttt gatcagataa
    31801 ggcatcttaa cattctcccg cccttttttc tcaatcagtt ttttcacaaa ttctggcatt
    31861 tgtaaatctt cagattcagc taaaatgttt ttcgtctcgt ctgaaggaac taactcatca
    31921 aaggtctctt cttctgggag aaattcctta aactcttgat tttcattgac tctaactgta
    31981 ttgaccaaag catcaatcaa acgagaatct gtatttggca ttggtgaacg atggtagttt
    32041 accccaaatt cctggcataa gtcataacat tctacatcat tgtcaaacaa gacctcaata
    32101 tgctcactga tgaaactaat aggtacaaaa atataatggt ctggatgttc tgtctgttct
    32161 ctgagatact ccaaaacaaa ggatcaccaa agtccaaggc aaaaatgggc acactatggg
    32221 ctgaaaagat gactttaaaa ctgtcttgct ttacttcttc ttttaaaatc ttagcaattt
    32281 catctgccca atagtttaag agcacttctt cctgatacca gtccttaatg accaaaaatt
    32341 gaatttgttt gctttctaaa aatttttcat agcccatgac agagtagaaa gaataatggg
    32401 gctccaaaat caagcaaata cactgttcaa ttccgtctgc ttccatttga ccgatcacat
    32461 ctggaataaa gggactggaa aacttattag caaagtagac actgtattca ttccccagcc
    32521 tagcttctac caaggtaacc tcttgacggg taattttttg cagaggcgtg cctccaattc
    32581 gtacataatt atcatagaga gtctgaatct cgtggtcttg gggtctcacc ccacgacgaa
    32641 tatttgtgaa aaaatcagct acaccttcaa aggtaatctc ttctggtgaa ccgaaggtca
    32701 tcattaaaat tgcttttttc atgactgctt ccttgtgatg tttttatcaa gtttatttta
    32761 tcattaattc atcgataagt aaacgctaac atagggacat tctcaatctt ctgtcttttg
    32821 tttttctctt ctttctatga tacaatggaa aaaataaatt caaaaggagt ttttttatga
    32881 cttatccaaa tctcttggac cgcttcttaa cctacgttaa ggtcaacacg cgctctgatg
    32941 aacactctac tactactcca agtacacaga gtcaggttga cttcgcaaca aatgtcctaa
    33001 ttcctgaaat gaaacgtgtt ggactgcaaa atgtttacta tctaccgaat ggttttgcta
    33061 ttggaacctt gccagccaac gatccgtctt taacacgtaa gattggtttt atatcgcaca
    33121 tggatactgc tgattttaat gctgaaggag tcaatccaca ggtaattgaa aactacgatg
    33181 gtggtgtgat tgaactaggg aattctggtt tcaaactcga tccagctgac ttcaagagtc
    33241 ttgaaaaata tccaggacaa acgctcatca caacagatgg aacaaccttg ctaggtgctg
    33301 atgacaagtc aggaattgct gaaattatga cagccattga atatctaact gctcatcctg
    33361 aaattaagca ctgtgagatt cgtgttggtt ttggtccaga tgaagaaatc ggtgttggtg
    33421 ccaataaatt tgatgcagaa gattttgatg tggattttgc ctacactgtt gatggtggtc
    33481 cactaggtga acttcagtac gagactttct cagccgctgg tgctgaattg catttccaag
    33541 gccgtaatgt ccaccctggt actgccaaag ggcagatggt caatgccctt cagctagcaa
    33601 ttgattttca taatcaactt ccagaaaatg accgacctga gttaactgaa ggttaccaag
    33661 gtttttacca tctaatggat gtgacaggta gtgttgagga ggcgcgtgca agctacatca
    33721 ttcgtgattt tgaaaaagat gcctttgaag cgcgtaaagc atccatgcaa tctatcgctg
    33781 ataagatgaa tgcagaactt gggagctacc gtgtcactct caacttgaca gaccagtact
    33841 acaatatgaa agaagtcatt gaaaaagata tgactccaat taccattgct aaagccgtta
    33901 tggaagatct aggtatcacg cctattatcg aaccaatccg gggtggaaca gacggctcta
    33961 agatttcctt tatgggaatc ccaactccga atatctttgc aggtggcgaa aatatgcacg
    34021 gacgttttga atacgttagc cttcagacta tggaacgtgc agttgatacc atcattggca
    34081 tcgtagctta taaaggctaa aaagacgagg tagctcagct acttcgcctt tctttttatt
    34141 ctactggttt ttcttgattt ccagtagttg tagaagattc tgttgtttca ttttctgaag
    34201 ttgattcagc aggtttagaa tctcttgtat tgcttggttt gttttcgtcg ctagcaattt
    34261 caatgttaga ttctgcagtt gcgtttggtt ggttctcagc actggtgtta tcactatttg
    34321 cttcagcatt tcttgctgga cttgtttctt cacttgcgct agcttttgac tggatttgat
    34381 gattcaaaac tagaatagct tttgtcgatt caagtaaagc tgttttgtct ttactcttag
    34441 cagaaagttg atctaataat gcatccacct tatcaaagtc cgcatcagat ccattattac
    34501 tttctaaatt ttccttttct tgttgaaggg cgctagcgat acgagtcaag acatctttta
    34561 cctgactgtt tacttcatcc aagtctgcat cagccttgtt tgtggcagct tttagatttt
    34621 ctacttcttc tgccaaggat tgtctgattc cttcttcatg gatttgttcc aagagttgat
    34681 ttaccttgct caaaagactt tctacttctt ccttgctatc tgtcgcagat tattggttgc
    34741 catctaccat gtactcctaa aacaggagag ttataatcca agattacaag gccttacaga
    34801 aataagaaat ccagataaga caatgttcgt ccaagacgct attcgcttcg cacagcagca
    34861 cggattcaat atgctttaat tttaaagttt aggtgtcaag acctcttttt agtgtgccca
    34921 aaatttagag aagtaatcaa tcaactaact tttatttttt tcaaactttc agtaaactga
    34981 cctaaagcta actcaatctg tctttgtaga tgcttctgct atcagctaga agttgatcta
    35041 cttttgccaa gactgccttc tcatcaaaag ttccaggttg atagttggat tgcagggatg
    35101 gaatcttgtt tttcaaagcc gcttcatatc ccttagtttg aaccttgatg tagtgattgt
    35161 ggtcgccatg aggaatcaca aaaccttctg aatcttcact tataattcga ttggcatcaa
    35221 aaccatgacc atcttcttcc tcatgatgga catgtagtga cggattactt aatacagaac
    35281 tagaagaact tcctacctct tccgtgttag agtgtgatgg gggattgtta agagatgact
    35341 taggaatata gtgatagtga tccccatgtc ttactatata agcatcacct gtatctctga
    35401 caatatcatt agggttaaag acatatgtgg ctgctaattc acctgccgac aagtcactct
    35461 caggaatgaa atgatagtga ccaccatgtg gtactatagt agattgaaat agaatatgag
    35521 caaattgata aggggatttt aaagtaattt ctaacaatga tttagaaact atgatgtgct
    35581 attctaaatt caactcacta tatataacca tcatcggtag tataacgtcc ctgtaatttt
    35641 gctacagata cttctgcact agctccttta tcgtctttac catgttcttg tttttggcga
    35701 ttgatttcat cttttgttcg tacattttct gcatgagctt gatctttaag gtaaacataa
    35761 tactttccat ctaccttaat aatatatcct cccttaacct aactgacgat atcttgatct
    35821 ttcggctgat agttgggggc tttcattaat agctcttcac taaagagcgc atcaaaagga
    35881 actttaccat tatagtagtg ataatgatcg ccatgagaag ttacataacc ttgatctgta
    35941 atcttaataa caatttgttt tgcttgaatt ccttcttttt gactaaccta gtctggagtc
    36001 aaattttcag tcttcttagt gtctttatta ctgtttacat atgaaacacg atttttatct
    36061 gtattggcct gttagctatg ttggttcaga gcataaacac acagacttaa ggaaaggata
    36121 acaacagatc cagctgctat atatttcttt ttaaatttca taattacctc atttctataa
    36181 ttatttatat gatgtcttca ttattaaatg attaaataaa ttaattaacc aattaattaa
    36241 ctagtaaata ttccacctct ttttaagttg tatgtcaaga aattttatat attaataata
    36301 aaatgaaatt ctcccaaagt cagagtttta tttctaactt ttgagagaac ttcatttttg
    36361 attcagactt tttctactgc tattccttac gctatgagat cagataaatt cttttttatc
    36421 acttctccac ttggcaatct taattcaatc gttccatcca tattgaatat aacactatct
    36481 aagcctaatc cgtaactagc tgtaaatttt tctaattttt cttgtacagg atctactgct
    36541 ggagcttcct ctaatgctgg atctaacata gggtcactcc ccacattccc ttctggattc
    36601 aacattccat tatccgttga gttttctggt tttacaggtt tttcgtttgg tgcctctggt
    36661 aaagaatctg ctggtttatt ttctgttggt tggttctcaa ctgttccagt agatactttt
    36721 ccagtttcag atggtttatt ttcaccattt ccttgaggtg cttctcctgt aaaatctgcc
    36781 atattctttt taatgacttc tcccgatggt aaatataatt caattgttcc gtccatatta
    36841 aacaagacat tttctagctt catcccataa ctttcagcaa attttgctac tttttcttgt
    36901 acaggatcca ctgtaggaac ttcttctaac gttgaatcac tagtactgtt cccagtttca
    36961 ggaagctttt ctttttctac cttctcacta gtctttggtt cttctacctt ttcatcaagt
    37021 tttgagtttt cttgtgcttt attcctttta aattgtggta gaatacttgg tttatcagtt
    37081 tgattttctt tttccaagat aggtacttcc acaatataag tcgattgatt gtccaaataa
    37141 gcatttgcca tgaaggttac aggaatttta tttccggccg ttctggttgt tccttggttt
    37201 aatttcggaa tcggtaattt aatttcacca actttatagt tattttctaa ataagcattt
    37261 ccatgaaatt catcaaacac tctgactaaa gcatcagttc ctttaggcac tgcaaattga
    37321 gggttcactc ttaaataagt atcccctgca tggaaaggat agaaaatcgt ttgactggcc
    37381 attttgtaag ctaaagaggt tggaactgta aatgtaccat cataacttac ttctggataa
    37441 tcttttgaag cgatagtata cttaaatgtt tgtcctggta aataaggttg atctaattca
    37501 aagtttgcaa tattccctac tccttctcca aatactttac cagatacttt ctccaatact
    37561 tttccatctg gtgttattaa ttttactagc atattgatac ctaatttttt ttccaattca
    37621 ggcggaaaac taaaagaaac gcgtttttga ccattggcta gagtaaagtt ttgattatta
    37681 aacgtactat tttttaacaa attaacaaca ttcgttaatt cttctccagt ataaacttta
    37741 ttcccttctt ttttagcaac tccttcttcg ggtttaaaca gttcatagtt actgtgagaa
    37801 tgaccaattc caaccggttt atgttcatca atcggatctg catgatggtg atctccatgc
    37861 ggataaataa tcgcattttt ttctttattc acgacaatac tttcacgttt gacaccatat
    37921 tgtttcataa tgccagcaat tttttcttcg atttttttat ctaaatcttt catttctttg
    37981 gcattacctg gataatcctg ttcatgagat gacaaagaat ctaatccatt atgactagtt
    38041 ttaacttcct ctaaatgttt ttgcgcagcc ttaatttgct cttctgtcaa gtccttcttg
    38101 aagaaataat gattgtggtc tccgtgactc atgacaaaac ctgattcatc ttcagcgata
    38161 atacgattag catcaaatcc gtatccatct tcttcatgtt tctcatgtga agttcctgga
    38221 ttgattggaa gagatggaga aggtgttgct agactattgt ttggaagagt cggttgccca
    38281 atttgatttg attttggaat gtaatggaaa tgatcaccat gtcttacaat ataagctgta
    38341 gccgtttctt caacgatatc ttttggatta aaaatataac catcagatgc tgaagagagt
    38401 ttcttacttg tcgttaaaga agaaggattg cttgaaagac tgcctagact agacactact
    38461 tcattaggtt ttgcatttgt agaaactgta gaaccagttc cactgatagg caccattctg
    38521 gcaatctttt cttctaaggc agaaagcttg ctgtaaggaa taaagtggta atggtcgcca
    38581 tgcggaatcg caactccatt tggtgtacga ctgataatct tagcagggtc aaagaccagg
    38641 ccatctgatt cactgtaacg ttgggcgcta ggtgaatcat agagttcctt caaaagactc
    38701 tggagatttt cagatttatt tgctggcttg ctagttgatc cttttgctac agattgcgtg
    38761 ttattgtcac tagctgttga agaatagctt aactgactcg gttgcatatt ttttccagcc
    38821 agatgtgctt tagctgctgc taattcacta gcagataaat cgcttttggg aatgtagtga
    38881 tagtgacctc catgaggaac gatataagca ttacccgtat cttcgataat atcagctgga
    38941 ttaaagacat aaccatcatt tgtcgtatat cgtccctgag accttgctac agcaacatta
    39001 gagttaacct tctcattatc tttgacatgt tcttgttttt gacgattgat ttcatcttta
    39061 gttcgaacat tatcagcatg agctgcatct ttcaggtaga cataatattt tccatcgacc
    39121 ttgatgatat aaccaccctt gacttcattg acaatatcag cgtctttaag ttgatagttt
    39181 ggatccttca tcaagagttc ttcactaaag agggcatcat aaggaacttt cccattatag
    39241 taatgatagt ggtcaccgtg tgacgttaca tagccctgat ctgtaatttt gattacaatt
    39301 tgctcagcct gaattccttc tttctggcta acctggtctg gtgtcaagtt ttcacttttc
    39361 tgacttgact ggctgccatc cacataagag acacgattat tgtccttatt ttcctgcgaa
    39421 cgatgctggt ttagtgcata ggcacataga ctcaaggata cgataacagc tgatccagct
    39481 gctatatatt ttttactaaa tttcataaat ccctcatttc aataaatgat gaagtttttt
    39541 tctcaacttc ttttacttta ttaaatagtt ttctaaaccg attatttaac catttaatta
    39601 accagtaaat agtctactat ttaaaattac ttttgtcaag tttctgttac gtttttctaa
    39661 aaaagagaag taacacgaaa ggttacttct ccataaaata tgctccattc attttactac
    39721 tgtataggag ccggttgact ttcttttaac aaagccaaga gactatctac ttctgctgaa
    39781 atagtattat tatctttcgt tccgagaaga agactacttt ttagaccagt caatgtctcc
    39841 atagcatttt gtctaatact agaatctgtt actttttcta gcaaggcctc cgcctctgct
    39901 atcttagcgt taataacaga atgctctact tgaggaattt cagcctcatc tgtagtatct
    39961 tcagcttctt cctctgtctc ttccgtatca gtgcttggtt tataaagatt atctgctgaa
    40021 ggatttaaac cagcgtgatt ctctttttca tcagattcag ggtgagttgg ctcacttact
    40081 tcatcatgtt ccttatcttc ctcaggtttt tctgtctgag gtttctccgt ttgattggta
    40141 tcagcttgac catttttgtt tctttgaaca tggtcgctag cgttaccaaa accattatct
    40201 gaatgcggac gttcgtttgg atgttcgaca tagtacttga cagtcgccaa aagatcctca
    40261 agagtatacc ccttaggtgc ctcataaagg ccttcgtcaa accactcaaa tttgatgtta
    40321 tggtaatggt cataatgagg tatgattaaa ctaccgtttt tgacttctac agtatattga
    40381 agattgtaag gcacacgatc aagtggcacc ttcttagctg ctttcacgcg gttgtagata
    40441 gcttctgctc cttttgcctc agtatttcct gaatcctgat g
//
LOCUS       DAVBNZ010000014        38411 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000014 DAVBNZ010000000
VERSION     DAVBNZ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.014"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQ860_000771"
     CDS             complement(56..1066)
                     /locus_tag="VQ860_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET3119229.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNALESATIVKLT
                     RTLAIIPITIFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQ860_000772"
     CDS             1215..2384
                     /locus_tag="VQ860_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3119230.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKVVILNYPANPTGITYSREQLETLAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQTIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQ860_000773"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQ860_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET3119231.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQ860_000774"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQ860_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET3119232.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDIGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQ860_000775"
     CDS             4146..4379
                     /locus_tag="VQ860_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3119233.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            4425..4715
                     /locus_tag="VQ860_000776"
                     /pseudo
     CDS             4425..4715
                     /locus_tag="VQ860_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4918..5148
                     /gene="blpU"
                     /locus_tag="VQ860_000777"
     CDS             4918..5148
                     /gene="blpU"
                     /locus_tag="VQ860_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET3119234.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5863..8016
                     /locus_tag="VQ860_000778"
     CDS             5863..8016
                     /locus_tag="VQ860_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET3119235.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8029..9378
                     /locus_tag="VQ860_000779"
     CDS             8029..9378
                     /locus_tag="VQ860_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET3119236.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9548..10255
                     /locus_tag="VQ860_000780"
     CDS             9548..10255
                     /locus_tag="VQ860_000780"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET3119237.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10457..14182
                     /locus_tag="VQ860_000781"
     CDS             10457..14182
                     /locus_tag="VQ860_000781"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET3119238.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDVTELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMNWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNSYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14275..15717
                     /locus_tag="VQ860_000782"
     CDS             14275..15717
                     /locus_tag="VQ860_000782"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET3119239.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPSNLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15754..16776
                     /locus_tag="VQ860_000783"
     CDS             15754..16776
                     /locus_tag="VQ860_000783"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET3119240.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTESAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16773..17318
                     /gene="purN"
                     /locus_tag="VQ860_000784"
     CDS             16773..17318
                     /gene="purN"
                     /locus_tag="VQ860_000784"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET3119241.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYIKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYLEVVKALFTD"
     gene            17402..17911
                     /locus_tag="VQ860_000785"
     CDS             17402..17911
                     /locus_tag="VQ860_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3119242.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17936..19483
                     /gene="purH"
                     /locus_tag="VQ860_000786"
     CDS             17936..19483
                     /gene="purH"
                     /locus_tag="VQ860_000786"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET3119243.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAKYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWEYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19605..20867
                     /gene="purD"
                     /locus_tag="VQ860_000787"
     CDS             19605..20867
                     /gene="purD"
                     /locus_tag="VQ860_000787"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET3119244.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21270..21758
                     /gene="purE"
                     /locus_tag="VQ860_000788"
     CDS             21270..21758
                     /gene="purE"
                     /locus_tag="VQ860_000788"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET3119245.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTILPVIGVPVNSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDQSIATALADFAEEQGKIAEESSNE
                     LI"
     gene            21745..22836
                     /gene="purK"
                     /locus_tag="VQ860_000789"
     CDS             21745..22836
                     /gene="purK"
                     /locus_tag="VQ860_000789"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET3119246.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDVVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKIATGGYDGHGQNVIRSADD
                     LEEAYALADSAACVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPAIKLHAPAVMLNVLGQHVEAAEKYVTENPSTHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            22846..23073
                     /locus_tag="VQ860_000790"
     CDS             22846..23073
                     /locus_tag="VQ860_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET3119247.1"
                     /translation="MIQIIVNAFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            23136..24434
                     /gene="purB"
                     /locus_tag="VQ860_000791"
     CDS             23136..24434
                     /gene="purB"
                     /locus_tag="VQ860_000791"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET3119248.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24489..28424)
                     /gene="strH"
                     /locus_tag="VQ860_000792"
     CDS             complement(24489..28424)
                     /gene="strH"
                     /locus_tag="VQ860_000792"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3119249.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEVS
                     STPSDKAEVVTQTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDEA
                     KAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDL
                     HLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDL
                     INYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVA
                     FTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEK
                     FIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASS
                     KLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPI
                     IGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYT
                     AESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKRE
                     VEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTIT
                     ANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPG
                     HMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIF
                     NFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYED
                     KDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGF
                     LKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFAD
                     HNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLV
                     ANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQ
                     ENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGL
                     APTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGK
                     EVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAE
                     ESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(28740..29456)
                     /locus_tag="VQ860_000793"
     CDS             complement(28740..29456)
                     /locus_tag="VQ860_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3119250.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29804..31591
                     /locus_tag="VQ860_000794"
     CDS             29804..31591
                     /locus_tag="VQ860_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET3119251.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31588..32064
                     /locus_tag="VQ860_000795"
     CDS             31588..32064
                     /locus_tag="VQ860_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3119252.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32092..32997
                     /locus_tag="VQ860_000796"
     CDS             32092..32997
                     /locus_tag="VQ860_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3119253.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32984..33799
                     /locus_tag="VQ860_000797"
     CDS             32984..33799
                     /locus_tag="VQ860_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3119254.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33806..34210
                     /locus_tag="VQ860_000798"
     CDS             33806..34210
                     /locus_tag="VQ860_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3119255.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34509..35675
                     /locus_tag="VQ860_000799"
     CDS             34509..35675
                     /locus_tag="VQ860_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET3119256.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35791..36828
                     /locus_tag="VQ860_000800"
     CDS             35791..36828
                     /locus_tag="VQ860_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET3119257.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37035..37889
                     /locus_tag="VQ860_000801"
     CDS             37035..37889
                     /locus_tag="VQ860_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3119258.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTCIRLAR"
     gene            38039..38279
                     /locus_tag="VQ860_000802"
                     /pseudo
     CDS             38039..38279
                     /locus_tag="VQ860_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
BASE COUNT        10750 a         7406 c         9116 g        11139 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtattaga
       61 aaatgccgat aagggtctgc ataccaaggc tggtgaggat gatggcaatc cagcagacgg
      121 ctccgagaac aatggatttt ccactggatt tgaccatagc gaccagatta gttttgagac
      181 cgatggcact catggccatg ataatgagga atttagagag ttgtttgaga ggggtaaaga
      241 aactactaga cacaccgaga gaggtcagaa gggtggttag gagcgatgca aggatgaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaagcc ttgcttattt ttttgctcgc
      361 gactttgcca gtaggagaga aagatagtga tggggatgat agctagggtg cgcgtgagtt
      421 tgacaatggt tgcggattcg agggcattgg tctggtagag actgtcccaa gcgctagctg
      481 tggcggttac agaggaagta tcattgaccg cagttcctgc aaagagggcg aagccgtcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggagatggct tgggctactt ccttttcctt agcatggata acaggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaatcaag gtagccagtt
      721 ttgtatccag ggcaaagaag cgctggaaga ggtaggcaac aatcaaggct attgaaatgg
      781 tggaaaggat gacagggagt gaagattgcc caactgcgaa gacttgagag atattgagac
      841 caaaaccaag caagataacg gcatactgga gcaatttctt ggaactaaag gtcaatccag
      901 catccagttg tttataagac gagagaaagg gatgtaggag catgcccata aaaatcgcaa
      961 aaacgggtgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcagac caagatgcct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 agaatctgtt accattatag acctgtaaag aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcgggaggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggcta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ctagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaatcttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggt ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga gaccttggca gctgttttac
     1801 gcaagtatga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccagac tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcgaccttca
     1981 cagcccagtt aatcaagagt caccagtact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaacgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggctgctgg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct gggcttatgt cgactttgcc gactgtagat
     3541 gggaagggat ttgacatgct agacctcggt gccaatgcgg aaaatacagc ccagcacctc
     3601 catcaatacg cggttctagg atccttctat gctaaaaatg ttcgtggcat tgcgcaacca
     3661 cgtgttggct tgctcaataa cggaacagag agtagcaagg gcgatccgct tcgtaaggaa
     3721 acttatgaat tactagtggc tgatgaaagt ttgaacttta tcggaaatgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacaac tcaattattc agatattggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aagaaattga ccaactccaa aacgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaactccacg taaatccagc aaactcaagc cgctaacagt tgaagataaa gcctgtaatc
     4561 atgcgctatc taaggagaga agcaaggttg agaatatctt tgccaaagta aaaacgttta
     4621 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga
     4681 ttgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct aatagtaaaa
     4741 aagtgattag aaaacatctt ttttaaaaat agagatgatt ttgaaacaaa aaagctaatt
     4801 caagacgttt ctatgccaat tcaagatttg gatgaaaaaa attaatagat actgttatac
     4861 taaacttgtc aagtttgtaa caagacaaat attaaaaata aaaaagaggt attcgttatg
     4921 aatacaaaaa agatgtcaca atttgaaatt atggatactg agatgcttgc ttgcgttgaa
     4981 ggtggcggat gcaattgggg agattttgcc aaagcaggtg ttggaggagg agcagtacga
     5041 ggtcttcagc taggaattaa aacaagaaca tggcaaggtg cagcaactgg tgctgcggga
     5101 ggagctatac ttggaggtgt ggcctatgca gcgacatgtt ggtggtaatt atggatttta
     5161 aaagttttat tattggttta gtagttggta tatttggtcc ttatatggat gatttaatta
     5221 gaaaaaaatt tttaaagtct tcggagaaga aaacagaaaa atctgttaaa aaataatcaa
     5281 aactataaat gatgaatctg aatcaaaatt attttgcgca tgtaaatagg agtcttatag
     5341 taacgagtca aaaaaggagt aactatgaat cgtaatttag aacggtgtta tctattctga
     5401 ctaggaatag atcataccag aggtagctta gaaatagcag agacattaga aattgaagta
     5461 ataaatagga tgtcgtaagt gttactatca atgatttatt tgtttcaagc ttgtctaggg
     5521 tgacagtaaa aaatcaattt cctttcaata gcatattttt agtgggcagt actcttgttc
     5581 tgcctatttt tttatccaaa aagtgcagtt gggagggaga taggctcatt tgggaaggaa
     5641 gtccagtttt tgtttagtga ttggggtaag atagttgtta tcagatgagt ttatactctt
     5701 cgaaaatcaa attcaaacca cgtcaacgtc gccttgccgt atatatgtga ctgacttcgt
     5761 cagtcctatc tacaacctca aaacagtgtt ttgagcagcc tgcggctagt ttcctagttt
     5821 gctctttgat tttcattgag tattagggaa aaggagatga atatgaaatt tgggaaacgt
     5881 cactatcgtc cgcaagtgga tcagatggac tgcggtgtag cttcattagc catggttttt
     5941 ggctactatg gtagttatta ttttttggct cacttgcgag aattggctaa gacgaccatg
     6001 gatgggacga cggctttggg cttggtcaag gtggcagagg agattggttt tgagacgcga
     6061 gccattaagg cggatatgac gctttttgac ttgccggatt tgacttttcc ttttgttgcc
     6121 catgtgctta aggaagggaa attgctccac tactatgtgg tgactgggca ggataaggat
     6181 agcattcata ttgccgatcc agatcccggg gtgaagttga ctaaactgcc acgtgagcgt
     6241 tttgaggaag aatggacagg agtgactctt tttatggcac ctagtccaga ctataagcct
     6301 tataaggaac aaaaaaatgg tctgctctct tttatcccta tattagtgaa gcagcgtggc
     6361 ttgattgcca atatcgtttt ggcaacactc ttggtaaccg ggattaacat tgtgggttct
     6421 tattatctgc agtctatcat tgatacctat gtgccagatc agatgcgttc gacactaggg
     6481 attatttcta ttgggctagt catcgtctac atcctccagc aaatcttgtc ttacgctcag
     6541 gagtatctct tgcttgtttt ggggcaacgc ttgtcgattg acgtgatttt gtcctatatc
     6601 aagcatgttt ttcacctccc tatgtccttc tttgcgacac gcaggacagg ggagatcgtg
     6661 tctcgtttta cagatgctaa cagtatcatc gatgcgctgg cttcgaccat cctttcgatt
     6721 ttcctagatg tgtcaacggt tgtcattatt tcccttgttc tattttcaca aaataccaat
     6781 ctctttttca tgactttatt ggcgcttcct atctacacag tgattatctt tgcctttatg
     6841 aagccgtttg aaaagatgaa tcgggatacc atggaagcca atgcggttct gtcttcttct
     6901 atcattgagg acatcaacgg tattgagact atcaagtcct tgaccagtga aagtcagcgt
     6961 taccaaaaaa ttgacaagga atttgtggat tatctgaaga aatcctttac ctatagtcga
     7021 gcagagagtc agcaaaaggc tctgaaaaag gttgcccatc tcttgcttaa tgtcggcatt
     7081 ctctggatgg gggctgttct ggtcatggat ggcaagatga gtttggggca gttgattacc
     7141 tataatacct tgctggttta ctttaccaat cctttggaaa atatcatcaa tctgcaaacc
     7201 aagcttcaga cagcgcaggt tgccaataac cgtctaaatg aagtgtatct agtagcttct
     7261 gagtttgagg agaagaaaac agttgaggat ttgagcttga tgaagggaga gatgaccttc
     7321 aagcaggttc attacaagta tggctatggt cgagacgtct tgtcggatat caatttaacc
     7381 gttccccaag ggtctaaggt ggcttttgtg gggatttcag ggtcaggtaa gacgactttg
     7441 gccaagatga tggttaattt ttacgaccca agtcaagggg agattagtct gggtggtgtc
     7501 aatctcaatc agattgataa aaaagccctg cgccagtaca tcaactatct gcctcaacag
     7561 ccctatgtct ttaacggaac gattttggag aatcttcttt tgggagccaa ggaggggacg
     7621 acacaggaag atatcttacg ggcggtcgaa ttggcagaga ttcgagagga tatcgagcgc
     7681 atgccactga attaccagac agaattgact tcggatgggg cagggatttc aggtggtcaa
     7741 cgtcagagaa tcgctttggc gcgtgctctc ttgacagatg cgccggtctt gattttggat
     7801 gaggcgacta gcagtttgga tattttgaca gagaagcgga ttgtcgataa tctcatggct
     7861 ttggacaaga ccttgatttt cattgctcac cgcttgacta ttgctgagcg gacagagaag
     7921 gtagttgtct tggatcaggg caagattgtc gaagaaggaa agcatgctga tttgcttgca
     7981 cagggtggct tttacgccca tttggtcaat agctagaaag aggagaggat gaaaccagaa
     8041 tttttagaaa gtgcggagtt ttataatcgt cgttaccata atttttccag tagtgtgatt
     8101 gtacccatgg cccttctgct cgtgttttta cttggctttg caactgttgc agagaaggag
     8161 atgagtttgt ccactagagc tactgtcgaa cctagtcgta ttcttgcaaa tatccagtca
     8221 actagcaaca atcgtattct tgtcaatcat ttggaagaaa ataagctggt taagaagggg
     8281 gatcttttgg ttcaatacca agaaggggca gagggtgtcc aagcggagtc ctatgccagt
     8341 cagttggaca tgctaaagga tcaaaaaaag caattggagt atctgcaaaa gagcctgcaa
     8401 gaaggggaga accactttcc agaggaggat aagtttggct accaagccac ctttcgcgac
     8461 tacatcagtc aagcaggcag tcttagggct agtacatcgc aacaaaatga gaccatcgcg
     8521 tcccagaatg cagcagctag ccaaacccaa gccgaaatcg gcaacctcat cagtcaaaca
     8581 gaggctaaaa ttcgcgatta ccagacagct aagtcagcta ttgaaacagg tgcttccttg
     8641 gccggtcaga atctagccta ctctttttac cagtcctaca agtctcaggg cgaggaaaat
     8701 ccccaaacta aggttcaggc agttgcacag gttgaagcac agatttctca gttagaatct
     8761 agtcttgcta cttaccgtgt ccagtatgca ggttcaggta cccagcaagc ctatgcgtca
     8821 gggttaagca gtcaattgga atcccttaaa tcccaacact tggcaaaggt tggtcaggaa
     8881 ttgacccttc tagcccagaa aatcttggag gcagagtcag gtaagaaggt acagggaaat
     8941 cttttagaca aggggaaaat tacggcgagt gaggatgggg tgcttcatct taatcctgag
     9001 accagtgatt ctagcatggt tgcagaaggt gccctactag cccaacttta tccatctttg
     9061 gaaagagaag ggaaagccaa actcacagcc tatctaagtt caaaagatgt agcaagaatc
     9121 aaggtcggtg attctgttcg ctatactacg actcatgatg ccgggaatca acttttccta
     9181 gattctacta ttacaagtat tgatgcgaca gctactaaga ctgagaaagg gaatttcttt
     9241 aaaatcgagg cggagactaa tctaacttcg gagcaggctg aaaaacttag gtacggggtg
     9301 gaaggccgct tgcagatgat tacgggcaag aaaagttatc tacgttatta tttggatcaa
     9361 tttttgaaca aagagtaatg ttcgtgtttt tagagttaaa taatttttaa actgtgagaa
     9421 agattcttct tgcagttttt tctttacaat ttttgaaaaa tatctactat ttattcggtt
     9481 aaattcttgt gttttttggt tttttgtggt aaaatgtgct caagtaatac gaaaggcgaa
     9541 ctttaaaatg tcaaaacaat tgatctattc gggaaaagct aaagatatct atacaactga
     9601 ggatgaaaat cttattattt caacttacaa ggaccaggcg actgctttca atggtgtcaa
     9661 gaaggagcag attgcaggta agggagtctt gaataatcag atctcatctt ttatttttga
     9721 gaaattaaat gcggctggtg tggcgactca ctttgtggag aaactttcag acacggaaca
     9781 actcaataaa aaggttaaga ttattccttt ggaagtcgtg ctccgcaact atactgctgg
     9841 ttccttttca aaacgttttg gtgtggatga aggaatcgcc ttggagactc cgattgtcga
     9901 attttactac aaaaatgatg atttggatga tccatttatc aatgatgagc atgtgaaatt
     9961 cctacagatt gcggatgacc agcagattgc ctacttgaag gaagaaacgc gtcgtatcaa
    10021 tgaactattg aaagtctggt ttgctgagat tgggcttaaa ttgattgact ttaagctaga
    10081 gttcggtttt gacaaggatg gcaagattat cttggcagac gaattttcac cagataactg
    10141 ccgcttgtgg gatgctgatg gcaaccacat ggataaggat gttttccgta gaggattggg
    10201 agaactaacc gacgtttatg agattgtttg ggaaaagttg caggaattga aataatctgt
    10261 ttgcaatgga aaaccttcgt ctctcaacta aaaggactca ggctgaaaag gtcccccaga
    10321 ccttttcact ctgtagagaa ctaggtgaac taaccgatgt ttacgaaatt gtctaggaaa
    10381 agttgcaggg tttaaaataa caacctcaag gctgtttggg aatattgcaa gagctgaaat
    10441 aaaggaataa gaattgatgg ataaacgtat ttttgttgaa aaaaaggctg attttcaggt
    10501 caagtcagag agtttggtta gagagctcca gcacaacttg ggactgtcaa gcttgaaaag
    10561 tattcgtatt gtgcaagtat atgatgtatt tgacttggct gaggacttgt ttgcacctgc
    10621 agagaagcac attttctctg agcaggtaac cgaccatgtt ttagatgaag tatctgtgca
    10681 ggcggatctt gctaactatg ctttctttgc cattgaaagt ctaccagggc agtttgacca
    10741 gcgtgcagct tcgtcacagg aagccttgct tttgttggga agttcgagtg acgtgacagt
    10801 caacacagcc caactttact tggtgaataa agatattgat gtgactgagt tggaagctgt
    10861 caaaaactac ctgctcaatc cagttgattc tcgtttcaag gatatcacga cagggattgc
    10921 caagcaggag ttttcagagt cagacaagac cattccaaaa ttgactttct ttgaaagcta
    10981 tacagcagaa gactttgctc gctacaaggc cgaacaaggg atggccatgg aagtggatga
    11041 tttgctcttt atccaagact actttaagtc aatcgggcgc gtgccaactg agactgaact
    11101 caaggttttg gacacttact ggtctgacca ctgccgtcat acgacttttg agacagagtt
    11161 gaaacacatc gacttttcag cttctaaatt tcaaaagcaa ttgcagtcaa cctatgacaa
    11221 gtatattgcc atgcgcgagg aattaggtcg gtctgaaaaa ccacaaacct tgatggatat
    11281 ggcgactatt ttcggtcgtt atgagcgtgc taatggacga ttggatgata tggaagtctc
    11341 tgacgaaatc aatgcctgct cagttgaaat tgaagtggac gttgatggtg tcaaggaacc
    11401 ttggctcctc atgtttaaaa atgaaaccca caaccatcca acagaaattg agccatttgg
    11461 tggagcggct acctgtatcg gtggagctat tcgtgatccg ttgtcaggcc gttcctatgt
    11521 ttaccaagcc atgcgtattt caggtgctgg tgatattaca gcaccgattt cggaaactcg
    11581 tgctgggaaa ttgccacaac aagtcatttc taaaacagca gctcatggtt attcttcata
    11641 tggtaaccag attgggcttg ccacaaccta cgttcgtgaa tacttccacc caggctttgt
    11701 agctaaacgt atggaacttg gtgccgttgt tggtgcggct cccaagggca atgttgtccg
    11761 tgaaaaacct gaagcaggtg atgtgatcat ccttctcgga ggcaaaacag gtcgtgatgg
    11821 tgtcggtggt gcgacgggct cttctaaggt tcaaacagtt gagtctgtag agactgctgg
    11881 tgctgaggtt caaaaaggaa atgccatcga agaacgcaag attcagcgcc tcttccgtaa
    11941 tggcaatgtc actcgtctga tcaagaagtc caatgacttt ggggcaggcg gcgtctgtgt
    12001 ggctatcggt gaattggcag acggtcttga aatcgacctc aacaaggtgc ctcttaaata
    12061 ccagggcttg aatggtacag aaattgccat ctctgaatca caagaacgga tggcggtcgt
    12121 ggttcgtcct gaagatgtgg atgccttcgt tgccgaatgt aacaaagaaa atattgatgc
    12181 tgttgtggtg gcgacagtaa ctgaaaaacc aaatcttgtc atgaactgga atggtgagac
    12241 aatcgttgac ttggagcgtc gtttccttga caccaatggt gtgcgcgtgg ttgtcgatgc
    12301 caaagttgtg gacaaggatg tcaaactccc agaagagcgt caaacatctg ctgaaacact
    12361 ggaatcagat acccttacgg ttctatctga cctcaaccat gcaagtcaaa aaggattaca
    12421 gactgtcttt gactgctctg ttggacgctc aacggttaat cacccacttg gtggtcgtta
    12481 ccaactcaca ccaactgagg catctgtgca gaaattgcca gttcaacacg gtgtgactca
    12541 tactgcgtcg gtcattgctc aaggtttcaa ctcatatgta gctgaatggt ctccatacca
    12601 cggtgctgct tatgcggtta tcgaagcaac tgctcgtttg gtggctgctg gtgccaactg
    12661 gtctaaggct cgtttctctt accaagaata tttcgagcgg atggacaagc aagcagagcg
    12721 ttttggtcag ccagtagccg cccttctagg ctctattgaa gctcagattc aacttggctt
    12781 gccatctatc ggtggtaagg actccatgtc tggtaccttt gaagaattga ccgttccgcc
    12841 aaccttggtt gcctttgggg tgacgacggc agatagccgt aaggtgctct ctccagaatt
    12901 taaagctgtt ggggaaaata tctactacat cccaggtcaa gccctctctg cagagattga
    12961 ttttgacttg attaagaaaa attttgctca gtttgaagca agccaagctg accataaagt
    13021 gacatctgca tcagctgtca aatacggtgg tgtagttgaa agtttggctc ttgctacctt
    13081 tggaaactat attggtgcag aggtgacctt gcctgaactt aaaacagctt tgacagctca
    13141 attaggcggc tttgtcttca catctcctga agaaattgct ggagtagaga agattggaca
    13201 aacgaaagca gactttacac tgactgtcaa cggtgtgaag ctagatggac acaagcttga
    13261 cagtgcattt caagggacat tggaagaagt ttacccaaca gaatttaccc aagcgaaaga
    13321 actagaagaa gtaccagctg tggcatcaga tgttgtgatt aaagccaaag aaaaggttga
    13381 aaaacctgtg gtttacatcc cagtctttcc aggaaccaac tcagaatatg attcagctaa
    13441 ggccttcgaa aaagaaggtg cagaggtcaa tttggtgcca ttcgtgacct tgaatgaaga
    13501 agctattgtc aagtcagttg aaactatggt tgacaatatc gacaagacta atattctctt
    13561 ctttgccggt ggattctcgg ctgcggatga accagatggt tcagctaagt ttatcgtcaa
    13621 tatcctgctt aatgaaaaag tgcgtgtggc tattgatagc tttatcgccc gtggtggctt
    13681 gattatcggt atttgtaatg gattccaagc cttagtcaaa tcgggtctcc taccatacgg
    13741 aaactttgaa gatgctaaca gtactagtcc aaccctcttc tacaatgatg ccaaccaaca
    13801 cgtggccaag atggtggaaa ctcgcattgc caataccaac tcaccatggt tggctggtgt
    13861 gcaagtgggc gatatccacg ctattcctgt ttcgcacggt gaagggaagt ttgtcgtgac
    13921 ggctgaggaa tttgcagagc tccgtgacaa tggacaaatt ttcagccaat acgttgactt
    13981 taacggtaaa ccaagtatgg attctaagta caatccgaat ggttctgtcc atgccatcga
    14041 aggaattacc agcaagaatg gtcaaatcat cggtaagatg ggccactcag aacgttatga
    14101 ggatggtctt ttccaaaata tcccaggcaa taaagaccaa cacctgttcg catcagcggt
    14161 taaacatttc actggaaaat aagacttaca gattttctaa tagatagtat cagtaatgta
    14221 aaagtcatgt aaatctagct cttgatgatt acaaatgaaa attaggtata aaaaatgaca
    14281 tacgaagtaa aatctcttaa tgaagaatgt ggtgttttcg gtatttgggg acatccagat
    14341 gctgctaagt tgacctactt tggactccac agtcttcaac accgtggtca ggagggggca
    14401 ggaatcctct ccaacgatca aggacaactg aagcgccatc gtgacatggg gcttttatca
    14461 gaagttttca gaaatccatc taatttggat aaattgacag gagctggtgc gattgggcat
    14521 gtgcgttatg cgactgctgg cgaagcttct gttgataaca tccaaccctt cctcttccgt
    14581 tttcacgata tgcagtttgg tttggctcat aatggaaatc tgaccaatgc agcctctctc
    14641 aagaaagaac tggaacaaag aggagcaatt ttcagcgcga cttcggactc tgaaatcttg
    14701 gctcacctca ttcgtcgcag tcataatcct agcctgatgg gcaaaatcaa ggaagcgctc
    14761 agccttgtca aaggtggttt tgcctatatc ttgctgtttg aggacaagtt gattgcggct
    14821 cttgacccta atggctttcg tccgctttct atcgggaaaa tggccaacgg agcggtggtt
    14881 gtttcctctg aaacctgtgc ttttgaggtc attggtgccg agtggatttg tgatttgaag
    14941 ccaggtgaga ttgtgatcat tgatgacgag ggcattcagt atgacagcta tacagatgat
    15001 acccagttgg cgatttgttc tatggagtat atctactttg cccgccctga ttctaatatc
    15061 cacggtgtca atgtccatac ggcacgtaag agaatgggag cgcaattggc gcgagaattt
    15121 aagcatgagg cagatattgt agttggtgtg cccaattctt ccctaagcgc ggctatggga
    15181 tttgcggaag aatcaggctt accaaatgaa atgggtctga tcaaaaacca atacacccag
    15241 cgaactttta tccaaccgac tcaagaattg cgggagcaag gagtgcggat gaaactgtct
    15301 gctgtttcgg gtgttgtcaa aggcaaacgt gtggtcatgg tggatgattc cattgtacgt
    15361 ggaacaacct ctcgtcgtat cgttcagctc ttgaaagaag cgggtgcgac tgaggttcac
    15421 gttgccattg gaagtcctgc actagcgtat ccatgtttct acgggattga tatccagacc
    15481 cgtcaggagc tgattgcagc caatcatacg gtcgaagaaa ctcgccaaat cattggtgcg
    15541 gacagtctga cttatctttc aattgatggc ttgattgagt cgattggtat cgaaacagat
    15601 gcgccgaacg gtggtctctg tgtcgcttac tttgacggtg actacccaac gcctctctat
    15661 gactacgaag aagactatcg tagaagtttg gaagaaaaga ccagttttta caagtaggcg
    15721 acagattctc cattaaagaa aaggaaaaaa taaatgacaa ataaaaatgc atatgcccag
    15781 tcgggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa gcacgtggcc
    15841 cgtacggaga gtgcaggtgt catgggagct cttggtggct ttggtggtat gtttgatctt
    15901 tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt cggaaccaag
    15961 ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg tgtggccatg
    16021 tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga ctacgtagcg
    16081 acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc agaaggttgt
    16141 gtgcaggctg gtgctgccct catcggtggg gaaacggctg aaatgccggg catgtacggc
    16201 gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt
    16261 gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag tgggattcac
    16321 tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta
    16381 ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg tatctatgtc
    16441 aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca catcacaggt
    16501 ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc tgaaattgat
    16561 gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg tcagattaaa
    16621 cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc ggtcagccct
    16681 gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat tggtcgcatc
    16741 gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg
    16801 gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt gtcttttcag
    16861 accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg tcctatgctt
    16921 ttgaactcaa ggagtttgag agcaaggcag actacgaagc agcccttgtc gaactcttgg
    16981 aagaacacca gattgacttg gtttgcctag caggctacat aaaaatcgtt ggaccaacct
    17041 tattgtcggc ttatgaaggt cggattgtca atattcatcc agcctacttg ccagaatttc
    17101 caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct ggtgtgacca
    17161 ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt cgtgtgccac
    17221 gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca gagtacaggt
    17281 tgtatctgga agtagtgaag gctctattta cagattgact ttttgatgat tcatatgata
    17341 tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt
    17401 aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga tgttattaac
    17461 ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt tcttagctcc
    17521 aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa aaattgtttt
    17581 tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt tccctttgat
    17641 aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta gtttattgtt
    17701 tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt tgactttaaa
    17761 tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag tgttcaaatc
    17821 acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg cttatcttgt
    17881 tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga atataatgac
    17941 taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg cccaagaact
    18001 caaaaaactt ggttgggaga ttatctcaac aggtggaact aaggttgccc ttgataatgc
    18061 tggggtggat accattgcta tcgatgatgt gactggtttc ccagaaatga tggacggtcg
    18121 tgtgaagacc ctccacccaa atatccacgg agggcttctc gctcgtcgtg acttggatag
    18181 ccacttggaa gcggctaagg acaacaagat tgagctcatt gaccttgtgg tggtcaacct
    18241 ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg cagttgaaaa
    18301 tatcgatatt ggtgggccat ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac
    18361 agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag caaacggcga
    18421 aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca cagcggctta
    18481 tgacgccttg attgcaaaat acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact
    18541 cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc aacaagacgc
    18601 ggacttttac cagaaagctt tgcctacaga ttactccatt gcttcagcca aacagctcaa
    18661 cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc gtatcatccg
    18721 tgacttcaaa gatagtccaa ccgttgtggc tctcaaacac atgaatccat gtggaattgg
    18781 tcaagctgat gacatcgaga ctgcttggga atacgcttat gagtctgacc cagtgtctat
    18841 ctttggtgga attgtcgtcc tcaaccgtga ggtggatgct gcgacagctg agaagatgca
    18901 cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc tagccatttt
    18961 gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag
    19021 cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt
    19081 ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa ccgagacaga
    19141 agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggcattat
    19201 cgtgaccaac gaccacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc
    19261 tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc ttgcttcaga
    19321 tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat
    19381 catccagccc ggtggctcag tccgtgacca agaatctatc gaagccgctg acaagtatgg
    19441 cttgaccatg gtcttcacag gagtgagaca ttttagacat taagaagata aaagggaaga
    19501 aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt
    19561 ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctgcttgttg
    19621 tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtgg
    19681 aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg gaattggtaa
    19741 atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat gatgttgctt
    19801 ggacctttat cggcccagat gatgcccttg ctgctggtat cgtggatgat tttaaccaag
    19861 ctgggcttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg tccaaggatt
    19921 ttgccaagga aatcatggtc aaatatggtg tttcgacagc agcctatggc acattttcag
    19981 attttgagga agcaaaggcc tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg
    20041 atggcttggc gcttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag
    20101 ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg
    20161 aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt gataagttct
    20221 acatcatgcc aacggctcag gaccacaaac gtgcctacga tggcgacaaa gggcctaaca
    20281 cgggtggtat gggtgcctat gcgccagttc cacacttacc acagagtgta gttgatacag
    20341 cggttgacac cattgtcaag ccagttctag aagggatgat taaagaaggt cgcccttatc
    20401 tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc atcgagttca
    20461 acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc tctgactttg
    20521 ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcacgtgg acggacaagg
    20581 gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagattat tcaaagggtg
    20641 ttgagttgcc agtcaaaacc gatggtgaca tcattaccta ctatgcaggg gctaagtttg
    20701 cggaaaatag cagagcgctg ctctcaaacg gcggacgagt ttatatgctc gttaccacag
    20761 cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa caaaaaatag
    20821 aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata
    20881 acgcgacgca gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa
    20941 tgttctggtc agggggaaac tttgagacct taggctcaaa gtttaggaat gaaaccgaag
    21001 gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa
    21061 atacgttaat ggtcgtatgg tttgcgagcg ttagcgagct aatatggagc aattaccgcc
    21121 gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa gaccttgggt
    21181 ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga
    21241 ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct
    21301 caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag
    21361 cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc aaacatgcag
    21421 aagaagcccg tagccgtggc atcaagatca tcatcgcagg tgctggtggc gcagcccatt
    21481 tgccaggtat ggtcgctgct aaaacaatcc ttccagtcat tggtgtgcca gtcaactctc
    21541 gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg
    21601 ttgcgaccat ggctatcggt gaagcaggtg cgacaaatgc ggccctcttc gctctccgtc
    21661 tcctctcagt agaggatcag tctatcgcga cagcattggc agatttcgca gaagaacaag
    21721 gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc
    21781 ggtcaactgg gtcagatgat ggccatttct gctatctaca tggggcacaa ggttatcgcg
    21841 ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt ggcaccttat
    21901 aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac ttacgagttt
    21961 gaaaatgtcg acgctgacgg tttggatgtc gttatcaagg atggacaact ccctcaagga
    22021 acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag
    22081 gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc
    22141 gacttgtcga aaaactatgt ccttaagatc gcaacaggtg gttatgatgg acacgggcaa
    22201 aatgtcattc gttcagcaga cgatttggaa gaagcctatg cattagccga ctcagcagct
    22261 tgtgtcttgg aagaatttgt caattttgac cttgagattt ctgtcatcgt gtcaggaaat
    22321 gggaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct
    22381 aagaccatcg taccagcccg tatttctgaa agtctagcag acaaggctaa agctatggca
    22441 gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgaca
    22501 gctgatgaca tcattgtcaa tgagattgct ccacgaccac acaactcagg ccactactct
    22561 attgaagcct gtgacttttc acaatttgac acgcatatat taggtgttct gggagcacca
    22621 ttgccagcca tcaaactaca tgcgcctgcc gtcatgctta acgttctcgg ccagcatgtt
    22681 gaggccgctg aaaaatatgt cacagaaaat ccaagcaccc acctccacat gtatggtaaa
    22741 atagaagcaa agcataatcg taagatggga catgtgactt tgtttagtga tgtaccggat
    22801 agtgtggaag agtttgggga agggattgat ttttaggaca agtctatgat acaaattatc
    22861 gttaatgcat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt gtatgctagt
    22921 gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata ccccgaaaat
    22981 tatttagcta tctatgatgt accgctggat acggatttga atacactaga tcattacccg
    23041 tctgtgttta ttggaaaaga ggagtttgag tagaaatctt ggtttaccta gatagcttat
    23101 tcccaacagc ttaagaagaa aggaaagatt aacacatgat caaccgttac tctcgccctg
    23161 agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag gtggaaatcc
    23221 tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg gctttgattc
    23281 gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag acgcgccacg
    23341 atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc aagtgggttc
    23401 actatgggtt aacttctacc gacgtggtgg atactgccta tggttacctc tacaagcagg
    23461 ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct gacaaggcca
    23521 aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct gagccgacaa
    23581 cttttggtct taaattggca acttggtata gcgaaatgaa acgcaatatc gagcgcttcg
    23641 agcatgcggc tgctggtgta gaagctggta agatttctgg tgcggttggg aactttgcca
    23701 atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt gcccaagaaa
    23761 tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt cttgccagca
    23821 ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa tctgagcaac
    23881 gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg cctcacaaac
    23941 gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt ggtcacatga
    24001 ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac tcatcagctg
    24061 agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac cgttttggaa
    24121 atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg aactcgactt
    24181 ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc atgacccgtg
    24241 agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac caagtagact
    24301 ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa gaagaaatcg
    24361 atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt gaacgtcttg
    24421 gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt attttttatc
    24481 gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt ggacatgagt
    24541 cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt tttctctgtt
    24601 accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc agttgatgga
    24661 gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc ttgtccgttt
    24721 tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac ggcttcctgt
    24781 gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt gctcacagag
    24841 tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt tcctttgagt
    24901 aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg gatatccagt
    24961 ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg agttacagga
    25021 gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc aaggactgtt
    25081 tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc acctttgact
    25141 cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt cttgataact
    25201 tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac attggcagcc
    25261 acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc ttgaagagcg
    25321 gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt gaggttgtaa
    25381 tttagagctg ttttagctgc gtcaagggcc tcaagacttt ctttactata tccttctaag
    25441 tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg gaagtagtct
    25501 ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt gtactcagcg
    25561 cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc tacttcagga
    25621 tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat agctttcttg
    25681 aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc accgttggta
    25741 ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt atatccccac
    25801 cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc gtccttgtct
    25861 tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt ggccatagct
    25921 gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt gaggtagtac
    25981 cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt gaaaatcttt
    26041 gttttacctg caaagaagtc catgtattta ccgataaggg cttttacaaa gttcatcgct
    26101 tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc ttgaggattt
    26161 ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg actgttaata
    26221 gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt tacttctgcc
    26281 tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc gataatagct
    26341 tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat atcatcgagt
    26401 agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc gagctcactg
    26461 gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc agcatcgatt
    26521 gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc ttcttttaga
    26581 gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat ggcttgatca
    26641 atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc tttttcagct
    26701 tcttttacgg ccgtgacgct ttctgcagta taacggttca ggtcttttgg tacctcgtta
    26761 agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc atttgcaaaa
    26821 tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt gtcagcccaa
    26881 gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg tacagaagtg
    26941 attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc ttggccatca
    27001 gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg gtgacctttt
    27061 tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt ccacatagaa
    27121 acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta gataccgtcg
    27181 ttaaaagcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc attggcgtag
    27241 gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta tttatcagct
    27301 tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc aagtccgatg
    27361 ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag ggcttttgta
    27421 aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt cccaaaatag
    27481 ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc atccatgtgt
    27541 ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata gttaatcaga
    27601 tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata atcatttgta
    27661 cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt agctgtgatg
    27721 ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg taaatcagtg
    27781 tagccataat gtttcgcttt atcgatgatt tccttgagtt gttctggtga gaaatattta
    27841 cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac agttgcagca
    27901 cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc atctttttta
    27961 gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac ctctttcgct
    28021 tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt ttcagcagaa
    28081 gtttgagtta ccacctctgc tttatcacta ggagttgaac taacttcctc ttgtggtttt
    28141 tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt ttctacagtt
    28201 tttggagctt ctggttgaag ctctgcttta ggtgtttcct cagtccgatt ttcggatgat
    28261 tgaggggaat cagaaactgt atggatggtc ggttggtttt ctgtagtagt agtaactcca
    28321 tcggctgcaa cagtctgtgc ttggaaggca aatccaatta gaacagaagc tgctcctaca
    28381 gcgtatttac gaatagaaaa acgctgttgt ttttcatgtt tcattgcaaa acctcctgat
    28441 tgcattgtta tattgatagc gattatataa atcaacgcct ttattttatt tcttatatta
    28501 acgagagtca agaggagatg acaaaaaact ataataagta taaaaaaata taaaatttaa
    28561 gcttaagatt tcagattggt cggaaaaaat acgtatatat atctagtata atttttggtt
    28621 ctatttctat aaaatattcc acaaattata gaatcttcca aaaataggta agcgctacct
    28681 ttttggtgtg gtataataag catagaaaaa gcccgagcga ttaggctcag gctttcttct
    28741 tagtgatcac ggtcacatga gatgaattta atcttgtagt aatcagatcg tttgtaagtt
    28801 tcactgtatt ctaaaacttg gccagttgat tcgagtttgg tgattttagt ttgtaggaca
    28861 gtagggaatt gttcatcgac tccgaggact gaagccgcat gttctggagt tggaaagact
    28921 atttcgttga tttcttcaaa gtgttcatca ttcatgtgaa tgtggtagtc taacttgaaa
    28981 cgattataga tagaactata gtattcaagg tttggataat ttgcgttgat atattgttct
    29041 gggatgtagg atgtatggta gatataaacg acaccgtttg attcgcggat acgttcaatc
    29101 ttgtagtaga attgatcgcc gcgtagaccc aatttttcca ggtaaacaag cttgtttccg
    29161 cgttcaattg aaagaacagt taccttatca tctttagcat tgaagagttc aatatctgaa
    29221 aactctacaa gcttgtgttt gcgtgcacgt gaaacgaagg ttccttttcc ttgttggcgg
    29281 acaatatagc catctttggc aaggtcgttt aaggcgcgaa caactgtgat agagctgaca
    29341 tcgtacattg aaatgagttc tgcttcagta taaaatttat ctccactgct aaactgccca
    29401 gagatgattt tattttttaa ttcgtctttt atgtattgat atttgggaat tgccatattt
    29461 ttacctctat tttccttctc catagaaaat tttaccataa aagcgaaaaa aatagtagtc
    29521 ttttgaataa aaaattagaa taatagtttg aaaaattaag ctatataggg attgatcata
    29581 ttttataaat gtattctata caaaattatt ttaggtccta tattccagat ttaaagagcg
    29641 tttgaaatgg gtctaaaaat gtttgaaact aattgaatgt gtgtataata gtaaaaatgc
    29701 agtaaatatc ccgacaattt ctattgacag ttcaaacaga ttggtttata attaatataa
    29761 caacaaatga aagcgcaaac tttcgcggtc ggaaggtagt tttatgacac gatttgagat
    29821 acgagatgat ttctatctcg atggaaaatc atttaagatt ttatctggtg ccattcatta
    29881 ttttagggtt cctccagagg attggtatca ttcgctctat aacttgaagg ctcttggttt
    29941 taatacggta gagacttatg ttgcttggaa tttacacgag cctcgtgaag gtgagtttca
    30001 ttttgaaggt gatctggatt tagagaaatt tctccaaata gcgcaggatt tgggtctcta
    30061 cgcaattgtg cgtccgtctc catttatctg tgcggaatgg gaattcggtg gcttaccagc
    30121 ttggctcttg accaagaaca tgcgaattcg ctcatctgac ccagcatata tcgaggcagt
    30181 tggtcgctac tatgatcagt tattgccaag actggtgcct cgtttgttgg acaatggtgg
    30241 caatattctc atgatgcagg ttgaaaatga gtatggttct tacggagaag ataaggctta
    30301 cctgagagcg attcgacagc taatggaaga gtgtggcgta acctgtcccc tctttacatc
    30361 agatggtcca tggcgagcta ctctgaaagc tggaacctta attgaagagg acctctttgt
    30421 aacaggaaac tttggttcta aggcacctta caacttttcg cagatgcagg aattctttga
    30481 tgaacatggt aagaaatggc cactcatgtg tatggagttc tgggatggtt ggttcaatcg
    30541 ctggaaagaa ccgattatca cacgggatcc taaggaattg gcagatgcag ttcgagaggt
    30601 tttggaacaa ggctctatca atctttacat gttccacggt ggtacaaact ttggtttcat
    30661 gaatggttgc tcagctcgag gaactttgga cctgccacaa gttacgtctt atgattacga
    30721 tgcccttctg gatgaagaag gaaatccaac tgctaaatat cttgcagtca agaagatgat
    30781 ggcaacacat ttttcagagt atccgcagtt ggaaccactc tacaaagaga gtatggagtt
    30841 ggatgctatt ccactagttg aaaaagtttc tttgtttgaa accttagata gcttgtcaag
    30901 tcctgtagaa agtctctatc ctcaaaagat ggaggagctg ggacaaagtt atggctacct
    30961 actttatcga acagaaacaa actgggatgc agaagaagaa agacttcgta tcattgatgg
    31021 tcgagatagg gcccagctgt atgtcgatgg tcagtgggtt aaaactcaat atcagacaga
    31081 gattggggaa gatatttttt atcaaggtaa aaagaaaggg ctatctaggt tagatatctt
    31141 gatagaaaat atggggcgtg tcaactatgg gcataagttc ttagcggata cgcaacgtaa
    31201 gggaattcgg acaggggtct gtaaggatct gcatttctta ctaaactgga aacactatcc
    31261 actcccacta gacaatcctg agaaaattga tttttcaaaa ggatggactc aaggacaacc
    31321 agccttttac gcttatgact ttacagtcga agagccaaaa gatacttacc tagacttgtc
    31381 tgagtttggt aagggggttg cctttgtcaa tgggcagaat ctaggacgtt tttggaacgt
    31441 tggcccaact ctctcacttt atatccctca tagctatctc aaggaaggtg ccaaccgcat
    31501 cattatcttt gaaacagaag gtcaatataa agaagagatt catttaactc gtaaacctac
    31561 actaaaacat ataaaggggg aaaacttatg acaattgtag gatgccgtat tgatggacgt
    31621 ttgatccacg gacaagtagc caatctttgg gctggaaaac taaatgtttc acgcattatg
    31681 gttgtagacg acgaagttgt caacaacgat attgaaaaga gtggtttgaa acttgcgaca
    31741 ccaccaggtg tgaaattgag tattttgcca gttgagaaag ctgcagccaa tattcttgct
    31801 ggcaaatacg atagccaacg tctctttatc gtggctcgta aaccagaccg cttccttggt
    31861 ttggtagaag caggtgtacc acttgaaacc cttaatgttg ggaatatgtc tcaaacacca
    31921 gaaactcgtt ctattacacg ttctatcaac gtagtagaca aggatgtgga agacttccac
    31981 aaactggcag aaaaaggtgt taaacttact gctcagatgg ttccaaatga tccaatttca
    32041 gactttttga gcttattaaa ataggaaaaa aatttttagg aggtcattgt tatgatacaa
    32101 tggtggcaaa ttttacttct cactttgtac tcagcttatc aaatctgtga tgagttgacg
    32161 atcgtttcat ctgcaggttc ccctgtattt gctggtttca ttactggttt aatcatggga
    32221 gatgtgacta ctggtttact tatcggtggt aacttgcaac tgttcgttct tggggttggt
    32281 accttcggtg gtgcttctcg tatcgacgca acttctggtg cggttcttgc gacagccttc
    32341 tctgtttcac aaggaattga tgcaccgctt gccattacta caatcgctgt accagtagca
    32401 gctctcttga cttacttcga cgttcttggt cgtatgacta ctaccttctt cgctcaccgt
    32461 gtggatgctg caatcgaacg ctttgactat aaaggtattg aacgcaacta cttgcttggt
    32521 gcgattccgt gggctctatc tcgtgccctt ccagtcttct ttgcccttgc ttttggtggt
    32581 gcctttgtac aatcagtagt agacttcgtt gaagcctaca aatgggttgc agatggcttg
    32641 acacttgcag gacgtatgct tccaggtctt ggatttgcaa tcttgcttcg ttaccttcca
    32701 gttaaacgta accttcacta ccttgctatg ggatttggtt tgacagctat gttgactgtt
    32761 ctttactcat atgtaacagg tcttggtggc gctgttgctg gtatcgtagg tactcttcct
    32821 gctgaagttg ctgaaaaaat tggtttcgtg aacaacttca aaggtttgtc tatgattggt
    32881 atttctatcg taggtatttt ccttgcagtg cttcacttca aaaatagcca aaaagtagct
    32941 gtagcagcac cttctacacc atcagaaagt ggggaaatcg aagatgacga attctaatta
    33001 caaacttaca aaagaagatt ttaatcaaat caacaaacgt agcttgttta ctttccaatt
    33061 aggttggaac tacgaacgta tgcaagcttc tggttacctt tacatgatct tgcctcagtt
    33121 gcgtaaaatg tatggtgatg gaactcctga attgaaagaa atgatgaaag ttcatactca
    33181 attcttcaat acttcaccat tcttccatac cattatcgct ggttttgacc ttgccatgga
    33241 agaaaaagat ggtgtaggtt caaaagacgc cgttaacggt atcaagacag gtttgatggg
    33301 accattcgct cctcttgggg atacaatctt tggttcactt gtacctgcta tcatggggtc
    33361 agtcgcagca actatggcta tcgctggcca accttggggg atcttccttt ggattgcagt
    33421 tgcagtagcg tatgacatct tccgttggaa acagttggaa tttgcttaca aagaaggggt
    33481 taaccttatc aacaacatgc aaagtacctt gacagctttg attgacgctg catctgtact
    33541 tggtgtcttc atgatgggtg ctcttgtagc aacagtgatt aactttgaaa tttcttacaa
    33601 gttgccaatc ggtgaaaaga tgattgattt ccaagacatc ttgaaccaaa tcttcccacg
    33661 tttgcttcca gcaatcttta ctgcctttat cttctggttg cttggtaaga aaggtatgaa
    33721 ctctactaaa gctatcggta ttattatcgt acttgctttg gctctttctg cccttggtca
    33781 ctttgcactt ggaatgtaat tccttatgac taaatcatta attttggtga gccatggtcg
    33841 cttctgtgag gagcttagag gtagcacaga aatgattatg ggcccacaag acaacattta
    33901 cacagtagct cttcttccag aagatggccc agaagaattt actgctaaat ttgaagctgt
    33961 tattgaagga ttggatgatt tcctagtctt tgcggatctt ctcggtggga caccttgtaa
    34021 tgtggtgagt cgcttgatca tggaaggtcg tgatattgac ctttacgcag ggatgaatct
    34081 tccaatggtg attgaattta tcaatgcgag ccttacaggc gcagatgcgg actacaagag
    34141 ccgtgctgca gaaagcattg tgaaagttaa tgacctgtta gcgggcttcg atgatgacga
    34201 agatgaataa tactcttcga aaatctcttc aaactacgtc aacgtcgcct tgccgtaggt
    34261 atatgttact gacttcgtca gtcttatccg gcaacctcaa aacggtgttt tgagctgact
    34321 tcgtcagtct tatccggcaa cctcaaagca gtgctttgag cagcctgcgg ctagtttcct
    34381 acagatttta gttggaactc gattcaattc atgtgacaac gtgaaaatcg ttagagcatt
    34441 ttatatagaa tatacatggg aatgtagctt actcccattc ccatatttaa tagaaaaaga
    34501 ggaactcaat gctacattat acaaaagaag acttgctcga attgggtgca gaaatcacta
    34561 cgcgtgaaat ctaccaacag cctgatgtat ggagagaagc ttttgaattt tatcaagcaa
    34621 aacgtgaaga aattgcagcc ttcctacaag aaatcgctga taaacatgac tatattaagg
    34681 ttatcttgac aggtgctggg acttctgctt atgtgggaga taccttgcta ccttatttta
    34741 aggaagtcta tgacgaacgc aaatggaatt tcaatgctat tgcgacaaca gatatcgttg
    34801 ccaatccagc aacctatttg aaaaaagatg tggcaactgt ccttgtgtct tttgctcgta
    34861 gtgggaactc gcctgaaagt gtggcgactg ttgatttggc caaatccttg gtggatgagc
    34921 tttatcaagt gacgattact tgtgcagcag atggtaaatt ggctcttcaa gctcacggtg
    34981 atgaccgtaa tctcttgctc ttgcaaccag ctgtctctaa tgatgctgga tttgccatga
    35041 cttctagctt tacgtctatg atgttgacag ctctcttggt ctttgatcct acagaatttg
    35101 ctgttaagtc tgaacgtttt gaagttgtat ctagtcttgc ccgtaaagtt ttagacaagg
    35161 cagaagatgt caaagagctt gttgatttag actttaaccg tgtcatctat ctaggcgctg
    35221 gtcctttctt tggacttgct catgaagctc agctcaagat tttggaatta actgctggtc
    35281 aagttgcgac catgtatgaa agcccagttg gcttccgtca cggtccaaaa tctcttatca
    35341 acgacaatac agttgttttg gtctttggta caacgacaga ctacactcgt aagtatgact
    35401 tggacttggt tcgtgaagtt gctggtgacc agattgctcg tcgtgttgtg cttttgagtg
    35461 atcaagcttt tggtcttgaa aatgtcaaag aagtggccct tggttgtggc ggtgtcttga
    35521 atgatattta ccgtgtcttc ccttacatcg tttatgccca actctttgcc ctattgactt
    35581 cactcaaggt agaaaataaa ccagatacac cgtctcctac aggtacagta aaccgtgtag
    35641 tacaaggtgt cataattcac gaatatcaaa agtaagacag tgtttatgaa ttcttgacaa
    35701 gaggatttgt aaattatcag ataaaccata gattgtcagt acgctttcta tggtttgttt
    35761 gcttgagaga aatagtaaaa ggagaacaga atgaaagcat acacagagcg tgtatttgga
    35821 aatgttgagg gcgaggatgt cttggcctat cgatttgaga cagacggtgg ctaccaactt
    35881 gaggttatga cttatggcgc gaccatcttg cgctatgtcg cacctgacaa ggctggaaat
    35941 tttgccaatg ttatcttggg atttgatgac tttgatagtt atgtaggcaa tagtcccaag
    36001 catggagcaa gtgtaggtcc tgtagcgggt cgtattgcag gtgcgacctt tgagctcaat
    36061 ggtaagacct atgaccttga ggttaataat gctagcaact gtaatcacag tggttcaact
    36121 ggttgggatt ccagcttgtt tgaagttgaa gaagtaagcg atcatggctt gactctctac
    36181 acagagcgta cagatgggac aggagggttc cctggaaatc tcaagatttg gatcagttat
    36241 cacttggaag aaactggtgc ctatgaaatc agctacaagg taacgaccga tcaggatacg
    36301 ctggtcaatc caaccaacca cagctatttc aacttgtctg gtgatttcac gcagacgatt
    36361 gaccgtcatg tcttccaact aaacacagag ggcatttact caatcgctcc tgacggtgtt
    36421 cctgccaaaa ctccagaagc caaccgtgat gtggtcaaac acgtctacaa tggtaccttg
    36481 ttgaaggata tctttgcaga agaagatgag caaatccagc tggcatcagg tttggatcat
    36541 ccatttgccc ttcctgcagg ccatgacaat gctggattcc tttatgacca aaattcaggt
    36601 cgcttcctgc ttttcaagac agaagctcct tgctttgtgg tctacacagc aaactttgtg
    36661 gatgaaagtg tcatcatagg aggtcagcca atgctacagc acaatgggat tgctcttgaa
    36721 gcgcaagctt taccagatgc cattcacagt gaccttaaag gccaagtcat tcttaaggct
    36781 ggtcaaacct tcaccagtaa gacacgttat gaacttgttg tgaaataaaa aagctggtca
    36841 aaaagtcttt aaaattaaaa taacgcatat tgtcaggtga tgaaaagttt gatactatgc
    36901 gttttgttat gaaatgattt actttatctt atcctgaaat ggtgttattt ttgagttatc
    36961 tggcttgact ttcttgatgg aaattatata atagttgtaa caataataat tacaacgaga
    37021 aaagaggacc atttatgacc tatgaataca agagtcacat ttatttggca gagacagttt
    37081 taaatgtaaa ggatttggcc agtcaaacag ccttttatca gcaagttatt ggtttagaaa
    37141 tcttatctca aactgagaca gagtccattc taggccttgg tggaaaagtc ttggtacagc
    37201 tgattcaagc acaagagagc ggagaagtga gggaacatta tggtctttac catttggcca
    37261 ttctcttacc cacacgcaag gctttggctg atgtcttgaa acacctgaca gatttacaga
    37321 ttcctcttgt cggcggtgca gaccatggtt acagtgaagc tatttacttg gaagatttgg
    37381 agggaaatgg cattgaactc tatcgagata agccagtttc cacatgggat attcgagaag
    37441 atggacgcat tatcggagtg acggaggctc ttgcggcgca ggacatttat gagttggggg
    37501 aaagagtaga gccctttatc ctggcagaag gtacgagaat ggggcatatt catctttcag
    37561 tcaaggatag tcgaaagtcc agccagtttt atcaaaaggt gttagggcta gaggataaat
    37621 tcagtgtgcc tagcgctagt tggattgcgg ctggagatta ccatcatcat ttagcagtta
    37681 acgaatgggg aggaaaaggt ctggcttcgc gtaagcaagg cttaccaggt ttagcctact
    37741 atgtcatcga agtcgcacat aaaaaagaac tgttaacgat tgcccaacga gcacaagaag
    37801 ttgacgcacc aatcaaatgg atgacatcga gccaattgga aatcacagac tcagatggca
    37861 tcgtgacctg tattcgttta gcaaggtaaa attaggaatt tttaataagt tataagtatt
    37921 gctagtttgc tttttgaacg gtctttggta acagaactgc gtgagctgga tgggtgagaa
    37981 ttttgacaaa gaagctgatt agagatataa tgaagaaaaa tcgagcaagg aaaaagaaat
    38041 gacaaattca aagtatatta ctcgtttgaa acgttcagag ggccagttgc gtgggattca
    38101 aaagatgatt gaaggagatc gtgacgcaac tgacagcagt gagatctagt gtagagcgcg
    38161 tgattgagat gataattacc gaaaatctta ctgaatgtat caatcagcca ctagatgatt
    38221 ctgaagctca aaaggaacgc ctagaaaagg ctatccgata cttgattaaa cggaaataaa
    38281 tgaatgtttt gagacgatat gtgcaaaggt ctattaacta ttagaatagt ttaatgtgag
    38341 tcaaaagaag ttgtaaaaaa tctttaaaat taaaaaaacg catagtatca ggtgttgaat
    38401 gtactgaccc c
//
LOCUS       DAVBNZ010000015        37863 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000015 DAVBNZ010000000
VERSION     DAVBNZ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.015"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..381
                     /locus_tag="VQ860_000803"
     CDS             <1..381
                     /locus_tag="VQ860_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3119259.1"
                     /translation="NLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHR
                     FLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIIDYIDY
                     YNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(426..1067)
                     /gene="plsY"
                     /locus_tag="VQ860_000804"
     CDS             complement(426..1067)
                     /gene="plsY"
                     /locus_tag="VQ860_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET3119260.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1203..3146
                     /gene="parE"
                     /locus_tag="VQ860_000805"
     CDS             1203..3146
                     /gene="parE"
                     /locus_tag="VQ860_000805"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET3119261.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3566..6037
                     /gene="parC"
                     /locus_tag="VQ860_000806"
     CDS             3566..6037
                     /gene="parC"
                     /locus_tag="VQ860_000806"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET3119262.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6169..7191
                     /locus_tag="VQ860_000807"
     CDS             6169..7191
                     /locus_tag="VQ860_000807"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET3119263.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7247..7951
                     /locus_tag="VQ860_000808"
     CDS             7247..7951
                     /locus_tag="VQ860_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3119264.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNGTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8016..8705
                     /locus_tag="VQ860_000809"
     CDS             8016..8705
                     /locus_tag="VQ860_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET3119265.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8702..9625
                     /locus_tag="VQ860_000810"
     CDS             8702..9625
                     /locus_tag="VQ860_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET3119266.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9640..10284
                     /gene="pcp"
                     /locus_tag="VQ860_000811"
     CDS             9640..10284
                     /gene="pcp"
                     /locus_tag="VQ860_000811"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3119267.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10452..10682
                     /locus_tag="VQ860_000812"
     CDS             10452..10682
                     /locus_tag="VQ860_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET3119268.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIVELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10732..10812
                     /locus_tag="VQ860_000813"
     tRNA            10732..10812
                     /locus_tag="VQ860_000813"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10766..10768,aa:Tyr,seq:gta)
     gene            10822..10893
                     /locus_tag="VQ860_000814"
     tRNA            10822..10893
                     /locus_tag="VQ860_000814"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10854..10856,aa:Gln,seq:ttg)
     gene            11055..12257
                     /gene="rpsA"
                     /locus_tag="VQ860_000815"
     CDS             11055..12257
                     /gene="rpsA"
                     /locus_tag="VQ860_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET3119269.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12343..12840
                     /locus_tag="VQ860_000816"
     CDS             12343..12840
                     /locus_tag="VQ860_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET3119270.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12840..14495
                     /gene="dnaX"
                     /locus_tag="VQ860_000817"
     CDS             12840..14495
                     /gene="dnaX"
                     /locus_tag="VQ860_000817"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET3119271.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14523..14717
                     /locus_tag="VQ860_000818"
     CDS             14523..14717
                     /locus_tag="VQ860_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET3119272.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14867..15637
                     /gene="sufC"
                     /locus_tag="VQ860_000819"
     CDS             14867..15637
                     /gene="sufC"
                     /locus_tag="VQ860_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET3119273.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15665..16927
                     /gene="sufD"
                     /locus_tag="VQ860_000820"
     CDS             15665..16927
                     /gene="sufD"
                     /locus_tag="VQ860_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET3119274.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIAHSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16938..18164
                     /locus_tag="VQ860_000821"
     CDS             16938..18164
                     /locus_tag="VQ860_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3119275.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVSATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18151..18591
                     /locus_tag="VQ860_000822"
     CDS             18151..18591
                     /locus_tag="VQ860_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET3119276.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18645..20057
                     /gene="sufB"
                     /locus_tag="VQ860_000823"
     CDS             18645..20057
                     /gene="sufB"
                     /locus_tag="VQ860_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET3119277.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20256..21497)
                     /locus_tag="VQ860_000824"
     CDS             complement(20256..21497)
                     /locus_tag="VQ860_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET3119278.1"
                     /translation="MKKIFLTLLTVSLLGGVSTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21600..22709
                     /locus_tag="VQ860_000825"
     CDS             21600..22709
                     /locus_tag="VQ860_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3119279.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23355..23702
                     /gene="ssrA"
                     /locus_tag="VQ860_000826"
     tmRNA           23355..23702
                     /gene="ssrA"
                     /locus_tag="VQ860_000826"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23885..23972)
                     /locus_tag="VQ860_000827"
     tRNA            complement(23885..23972)
                     /locus_tag="VQ860_000827"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23936..23938),aa:Ser,seq:gga)
     gene            24134..24874
                     /locus_tag="VQ860_000828"
     CDS             24134..24874
                     /locus_tag="VQ860_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3119280.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24871..25782
                     /gene="pfkB"
                     /locus_tag="VQ860_000829"
     CDS             24871..25782
                     /gene="pfkB"
                     /locus_tag="VQ860_000829"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET3119281.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25779..27731
                     /locus_tag="VQ860_000830"
     CDS             25779..27731
                     /locus_tag="VQ860_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3119282.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27895..30120
                     /locus_tag="VQ860_000831"
     CDS             27895..30120
                     /locus_tag="VQ860_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3119283.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30273..30701)
                     /locus_tag="VQ860_000832"
     CDS             complement(30273..30701)
                     /locus_tag="VQ860_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119284.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            30839..31981
                     /locus_tag="VQ860_000833"
     CDS             30839..31981
                     /locus_tag="VQ860_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3119285.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31990..33204
                     /gene="thiI"
                     /locus_tag="VQ860_000834"
     CDS             31990..33204
                     /gene="thiI"
                     /locus_tag="VQ860_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET3119286.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33339..34163
                     /locus_tag="VQ860_000835"
     CDS             33339..34163
                     /locus_tag="VQ860_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3119287.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            34176..35342
                     /locus_tag="VQ860_000836"
     CDS             34176..35342
                     /locus_tag="VQ860_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3119288.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            35850..37343
                     /locus_tag="VQ860_000837"
     CDS             35850..37343
                     /locus_tag="VQ860_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3119289.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37356..>37863
                     /locus_tag="VQ860_000838"
     CDS             37356..>37863
                     /locus_tag="VQ860_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3119290.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLL"
BASE COUNT        11456 a         6884 c         8388 g        11135 t
ORIGIN      
        1 aatctttcaa cttcacccaa cttagaacaa gtacaaacaa tgttggaaca ggcattcaca
       61 gagaagcact acgagaatac gattctccat agtgaccaag gctggcaata tcaacacgat
      121 tcttatcatc ggttcttaga gagtaaggga attcaagcat ccatgtcacg caagggaaac
      181 agccaagaca atggtatgat ggagtccttc tttgggattc tgaaatcgga aatgttttac
      241 ggttatgaga agtcgtttca gtcgcttaag caattggaac aagccattat agactatatt
      301 gattactaca acaacaagag aattaaggta aaactaaaag gacttagccc tgtgcaatac
      361 agaactaaat ccttcggata aattaattgt ctaacttttg gggggcagtt cacagaactg
      421 gcattttatt ttttaggatc ttgatgggtt aggttcaatc cccaagggac caaattttca
      481 gttttatttt tgatacgagc tatattgtcc ttatgacgaa tgataatcaa actagcaagt
      541 gctaagataa tagcgatgaa gagagagtca tagttactca ggataaaacc aaaaagtgga
      601 aagagcagaa ccccgataac agccgcgatc gatgctgtga cactagacag tgaaatcata
      661 ctgccaagat agagagctcc aaagaagata atcgcaaggt agagacagaa gataggcgca
      721 aatccgaaaa ttactccagc actggttgcg acagccttac cacctttaaa tcctgcaaag
      781 atagggaagg tatggccgat aacagccaaa agtccaaaga tgagaggaga aacgccttgt
      841 agatgaaaaa taatcggaag cagcgttgct agggttcctt tgaaaaagtc aatcacaaag
      901 gttgccatac cagctttctt acctaaaatg cggaaggtat tggtcgttcc agtgttacca
      961 gaaccatgct cgcgtagatt gatttgaaag aatacttgtc caatccagag accagatgga
     1021 atcgaaccca gcagataggc taggattaat aaaactattg taatcatact cctattatat
     1081 catgaattgg gaaagaaaag cagagaatct ctgctaaaat tgtcacatcg gagaaagaaa
     1141 aattttgcaa aatccttgga aaacctgtag aatagtaaag atgaacgaat aggaggttcc
     1201 ttgtgtcaaa aaaggaaatc aatattaaca attataatga tgatgctatt caggtgctag
     1261 aagggttgga tgcggtccga aaacgtccag ggatgtatat tggatcgacc gatggcgctg
     1321 gtcttcatca cctagtttgg gaaatcgttg ataatgcagt cgatgaagcc ttgtctgggt
     1381 ttggtgatcg tatcgatgta accatcaata aagacggtag tctaacggtt caagaccatg
     1441 gacgtgggat gccgacaggt atgcacgcta tgggaattcc aactgttgag gttatcttta
     1501 ccattcttca tgccggaggg aaattcggtc aaggtggcta taagacatca ggtggacttc
     1561 acggagtggg ttcttccgtt gttaacgccc tttctagctg gttagaagtt gaaattaccc
     1621 gtgatggcgc agtttacaag caacgtttcg aaaatggtgg aaaacctgtc acgactttga
     1681 agaaaatcgg tacagcaccc aagtctaaaa caggcaccaa agttactttt atgcctgacg
     1741 cgactatatt ttctacgaca gatttcaagt acaataccat ttcagagcgc cttaatgaat
     1801 cagcctttct cttgaaaaat gtgaccttgt ctttaacgga caagcgaaca gatgaagcga
     1861 ttgagttcca ctatgagaat ggagtacaag attttgtttc ttatctcaac gaagataagg
     1921 aaatcttgac gccagttctt tactttgaag gggaagacaa tggttttcaa gtggaagtag
     1981 ccctccagta caatgacgga ttctcagata acattctatc ctttgtcaat aacgttcgca
     2041 ccaaggacgg tggaacgcac gagacaggac tcaagtctgc cattaccaag gtcatgaatg
     2101 actatgcacg taaaacaggt cttctcaagg aaaaagataa aaaccttgaa ggttcagact
     2161 atcgtgaggg actagcggcc gttctttcta tcttagttcc tgaagaacac ttgcagtttg
     2221 aaggacagac caaggataaa ctaggaagcc ccctagctcg cccagttgtg gatggaatag
     2281 tggctgataa gttgaccttt ttccttatgg aaaatgggga attagcttct aacctcatcc
     2341 gcaaggctat caaggcccgt gatgctcgtg aagcagcacg taaggcgcgt gatgagagcc
     2401 gaaatgggaa gaaaaacaag aaagataagg gcttgttgtc tgggaaattg accccagccc
     2461 aatctaagaa tcctgctaag aatgaactct atctagttga gggggactct gccggtggtt
     2521 ctgccaaaca aggtcgtgac cgcaagttcc aggctattct acctcttcgt ggtaaggtta
     2581 tcaatacagc caaggccaag atggcggata tcctcaaaaa tgaagagatc aataccatga
     2641 tttataccat tggtgcgggt gttggagcag acttctctat tgaagatgcc aactatgata
     2701 agatcattat catgaccgat gcggataccg acggtgccca tatccagacc ttgctcttga
     2761 catttttcta ccgttacatg cgtccgctag tcgaggcagg tcatgtctat attgccctcc
     2821 cacctcttta caagatgtcc aaaggtaaag gaaagaaaga agaagtggcc tacgcttgga
     2881 cggacggaga actagaagaa ctccgtaaac agttcggtaa aggcgctacc ctccaacgat
     2941 acaaaggact tggtgagatg aatgcggacc agctctggga aacaaccatg aacccagaaa
     3001 cacgtaccct catccgtgtc acaattgaag atttagcgcg cgccgaacgc cgcgtcaatg
     3061 ttctcatggg agataaggta gaaccacgcc gtaaatggat tgaagataat gtcaagttta
     3121 cgctagaaga agcgacagtg ttttaatgaa agaaaataat atgttagtaa actggaaatt
     3181 agagtcggat gtgaatgact atgtgaaaaa gcagtttgaa aatcttggtt tgaaaaaatt
     3241 gcaggattat taatgaagaa tctgctatga gtgcttatct caaagaggcg cttaagggag
     3301 cggctaagac acaaactaag actaattttg gaaaaccaga ttttcatatt gaaaaataca
     3361 aacaggatag tttggttact tatcgtaact gaacacggga ggaattcccg taaaatatct
     3421 tttactgcat aaaaacctac tctacattct ttgaaaggag ttgaacacgc cctagatact
     3481 gtgtgaaaaa gataaattct cttgtgagtt tgcttacttc aagaattttc tattttcact
     3541 tggtatttta tgggctttgt atcttatgtc taacattcaa aacatgtccc tggaggacat
     3601 catgggagag cgctttggtc gctactccaa gtacattatt caagaccggg ctttgccaga
     3661 tattcgtgat gggttgaagc cggttcagcg ccgtattctt tattctatga ataaggatag
     3721 caatactttt gacaagagct accgtaagtc ggccaagtca gtcgggaaca tcatggggaa
     3781 tttccaccca cacggggatt cttctatcta tgatgccatg gttcgtatgt cacagaactg
     3841 gaaaaatcgt gagattctag ttgaaatgca cggtaataac ggttctatgg acggagatcc
     3901 tcctgcggct atgcgttata ctgaggcacg tttgtctgaa attgcaggtt accttcttca
     3961 ggatatcgag aaaaatacag ttccttttgc atggaacttt gacgatacgg agaaagaacc
     4021 aacggtcttg ccagcagcct ttccaaacct cttggtcaat ggttcgactg ggatttcggc
     4081 tggttatgcc acagacattc ctccccataa tttagctgag gtcatagatg ctgcagttta
     4141 catgattgac cacccaactg caaagattga taaactcatg gaattcttgc ctggaccaga
     4201 cttccctaca ggggctatta ttcagggtcg tgatgaaatc aagaaagctt atgagactgg
     4261 gaaagggcgc gtggttgttc gttccaagac tgaaattgaa aagctaaaag gtggtaagga
     4321 acaaatcgtt attactgaga ttccttatga aatcaataag gccaatctag tcaagaaaat
     4381 cgatgatgtt cgtgttaata acaaggtagc tgggattgct gaggttcgtg atgagtctga
     4441 ccgtgatggt cttcgtatcg ctatcgaact taagaaagac gctaatactg agcttgttct
     4501 caactactta tttaagtaca ccgacctaca aatcaactac aactttaata tggtggcgat
     4561 tgacaatttc acacctcgtc aggttgggat tgttccaatc ctgtctagct acatcgctca
     4621 ccgtcgagaa gtgattttgg cgcgttcacg ctttgacaaa gaaaaggctg agaaacgtct
     4681 ccatatcgtc gaaggtttga ttcgtgtgat ttcgattttg gatgaagtca ttgctcttat
     4741 ccgtgcttct gagaataagg cggacgccaa ggaaaacctc aaagttagct atgattttac
     4801 ggaagaacag gctgaggcta tcgtaacttt gcaactgtac cgtttgacca ataccgatgt
     4861 ggttgtcttg caggaagaag aagcagagct tcgtgagaag attgctatgc tggcggctat
     4921 tatcggtgat gaaaggacta tgtacaatct catgaagaaa gaacttcgtg aggtcaagaa
     4981 gaaatttgca actcctcgtt tgagttcttt agaagacact gcgaaagcaa ttgagattga
     5041 tacagctagt cttatcgctg aggaagatac ctacgtcagc gtgaccaagg caggttacat
     5101 caagcgtacc agtccacgtt cctttgcggc ttccaccttg gaagaaattg gcaagcgtga
     5161 tgatgaccgt ttgatttttg ttcaatctgc caagacaacc cagcacctct tgatgttcac
     5221 aagtcttgga aatgtcatct acagaccaat ccatgagttg gcagatattc gttggaagga
     5281 catcggagag catctgagcc aaaccatcac aaactttgaa acgaatgaag aaatccttta
     5341 tgtggaagta ctggatcagt ttgacgatgc gacaacctac tttgcagtga ctcgccttgg
     5401 tcaaatcaaa cgggtagagc gaaaagaatt cactccatgg cggacctata gatctaagtc
     5461 tgtcaagtat gctaagctca aagacgatac agatcagatt gtagcagtgg ctccgattaa
     5521 actagatgat gttgtcttgg ttagtcaaaa tggttatgcc ctgcgtttca atatcgaaga
     5581 ggttccggtt gtcggtgcta aggcagcagg tgtcaaggct atgaatttga aagaagatga
     5641 tgtcctccaa tctggcttta tctgtaatac ttcgtccttc tacctcttga cccagcgtgg
     5701 aagcttgaaa cgtgtttcta ttgaggaaat tctagcaacc agccgtgcca aacgaggatt
     5761 acaagtcttg cgtgagttga aaaacaaacc gcatcgtgtc ttcttggcag gagcagttgc
     5821 agagcaagga tttgttggcg atttcttcag tacggaagtg gatgtgaacg accaaactct
     5881 gcttgtccaa tccaataaag gaacaatcta tgaaagccga ttgcaagact tgaacttgtc
     5941 agaacgcact agcaatggaa gcttcatttc tgacacgatt tcagatgaag aagtttttga
     6001 cgcttatctt caggaagtag ttactgaaga taaataagtg aaatgaagaa tcagttctaa
     6061 gagctggttt ttattggaga aattttctga aaattacaaa atatacttgc tattttagaa
     6121 aaatagtgta gaatataaga aataggtttt tagaataagg agtggaatat gacagtaacg
     6181 attgattggg aaaacctcgg tttttcctat atgaaattac cttatcgcta tcttgctcat
     6241 ttcaaaaatg gacaatggga tcaaggagag cttacagagg atgcaacttt gcatatttca
     6301 gagtcttctc caagtcttca ctatggacaa caagcatttg aaggtttgaa agcttatcgt
     6361 actaaggatg gcagtgttca actgttccgt cctgatgaaa atgctaaacg tctgcaacgt
     6421 acatgtgacc gtctcttgat gccacaagtt ccgacagaca tgtttgtaga agcttgtaaa
     6481 gcagttgtcc gtgcgaatga agaatacgta ccaccatacg gaacaggtgg aaccttatat
     6541 cttcgccctc ttttgattgg tgtcggagat attatcgggg taaaaccggc agaagagtac
     6601 attttcacca tctttgctat gccagttgga aattacttta aaggtggttt ggtcccaacc
     6661 aacttcttga ttcaggatga gtacgaccgt gcagcaccaa atggtacagg tgcggctaag
     6721 gttggtggaa actatgctgc aagtctctta ccaggaaaaa tggccaagtc acgtcatttc
     6781 tcagatgtta tctatctgga cccatcaact catacaaaga ttgaagaagt cggatcagct
     6841 aacttctttg gaattacagc tgataatgaa tttgtaacac cattgagtcc atctatcttg
     6901 ccatctatta ccaagtattc cttgctttat ttggcagaac atcgcttggg attaactcct
     6961 attgagggtg atgttccaat tgataatctt gaccgttttg tagaggcagg tgcctgtggt
     7021 acagcagcgg ttatttctcc aattggaggt attcaacatg gtgatgattt ccatgtattc
     7081 tatagtgaaa cagaagtagg tcctgtgacg cgtaaattat ataatgaatt gacgggtatt
     7141 cagtttggcg atattgaagc gccagaaggt tggattgtaa aagtagatta aaataaacca
     7201 aaggagattt tttatgaaat agaaaaagtg gctcttaaca gcaggagtgg tcctgagcac
     7261 gtcagctatt ttagtggctt gtggaaaaac tgataaagaa gcagatgcac cgacaacatt
     7321 ttcttatgtc tatgcagtag atccagcatc attgggctac agtatagcga ctcgaacatc
     7381 gaggacagac gttattggaa atgttattga tggtttgatg gaaaatgata aatacggcaa
     7441 tgttgctcct tctcaaaaag actatgattt gaacggtaca ggatgggctc caagctatca
     7501 agatccagcg tcttacttga atattatgga tccaaaatct ggttctgcca tgaaacacct
     7561 tggcattacg aaaggaaaag ataaggatgt tgtagctaaa cctggtttgg ataaatataa
     7621 gaaattgtta gaagatgctg tttctgagac cactgaccta gagaagagat atgaaaaata
     7681 tgccaaagct caagcttggt cgacagatag ttcattattg atgccaacag cttcatctgg
     7741 tggttttcca gttgtaagta acgtagtacc attctcaaaa ccatactcac aagttggtat
     7801 taagggggaa ccatatatct ttaaaggaat gaaattgcaa aaagatattg ttacaacaaa
     7861 agaatataac gaggttttta aaaaatggca aaaagaaaaa ttggaatcca atagcaaata
     7921 ccaaaaagaa ctagaaaaat acattaaata aggaatggta ttgatcttga taaaattttt
     7981 aaaatactgt cattttgaat ataaaggagt ttgatatgga gtggattaga ttaataggaa
     8041 tagcaatcat tgttgtgggt tttattttaa aatttgatac aattgcaaca gtagtcttag
     8101 ctggtttggt tacagcttta gtttcaggtg tttctctcgt tgaatttttg gagattttgg
     8161 gaaaagaatt tagcaatcag cgagtgctca cgatttttat ggttaccttg cctcttgtgg
     8221 ggctgtcaga aacctttgga ctcaagcaac gatcaatcga tttgattcga aagattaaag
     8281 gtctgacagt tggaaacttc tatacagttt atttctttat tcgagagtta gctggtttct
     8341 tttcaattcg tctaggagga caccctcagt ttgtcagacc tttggttcaa cctatgggag
     8401 aagcagctgc agagtctcaa ttaggtagaa agttaacaga ggttgaagat gagacaataa
     8461 aagcgcgtgc ggctgcgaat gaaaattttg gaaatttctt tgctcaaaat acgtttgtag
     8521 gtgctggggg agtcctcttg atagggggaa cattagatca gttaggctat gaaagcaatt
     8581 atgcagggat tgcttctaca tctattattg ttgctgttat aacacttatt gtagtgggga
     8641 tttacaatta tttatttgat aaaaaattga tatcaaaaaa gactagggga ggagaacaaa
     8701 aatgacagag ttggcaaagc aactattaga gttgacctat attgtgattg gttgtcaatt
     8761 tctccataca gcctattgta gttataaaga taaaacaaac ccagttcgac ttgggacatc
     8821 tgcattttgg actctattgt ctattacgtt tataggtggt tcctatatgc caaatatgag
     8881 tattggtatt attgtaatcc tattatcgct gttaacattg tttaagcaag tccgtatcgg
     8941 aaccttgcca tccttagatg aaatgaaagc caatattgaa tctaacaggt tgaaaaataa
     9001 aatttttatt ccagttatgc tgatggcaat acttgcgttg gtcttagcgc aaatgattcc
     9061 agaatttagc aagatttcga ttagccttgc cgccttgttt gctacaattt ctgttcttgt
     9121 gattaccaat agtcacccta agagtctgtt atcagaaaat aatcgaatga ctcagcaagt
     9181 ttcaacaagt ggtattgttc ctcaattatt aggggctttg ggggctattt ttactgtagc
     9241 aggtgttggt gatgttatct ctcatctgat tagcggtatt gttccttcag atagtcgctt
     9301 tataggagtt ttggcttatg ttcttggaat ggttctattc acaatgatta tgggaaatgc
     9361 ttttgcagca ttcaccgtta ttacagcagg tgttggagtt ccctttgtat ttgctctggg
     9421 agctaatcca attgtggctg gtgctcttgc catgacagca ggttattgtg ggaccttatt
     9481 gaccccaatg gctgctaatt ttaacgctct accagcagca ttgatggata tgaaagatca
     9541 gaatggcgtt ataaaggctc aagcaggtgt tgctctagta atgattgtta ttcacatatt
     9601 cttaatgtac tttctcgcat tttagtaaag gaaaataaaa tgaaaatatt ggttacaggt
     9661 tttaatcctt ttggaggtga aaagattaat ccagctttgg aggctgtaaa attattacca
     9721 tctgagatta atggggctga agttcgctgg gtagaaattc caacggtttt ttataagtcg
     9781 tcagaagttt tagaggcaga aatattacga tatcaaccag atgctgtact ttgtattgga
     9841 caagcaggcg gcaggaccgg cttaacacct gaacgagtgg ctattaatca agatgatgct
     9901 cgcatacctg ataacgaagg caatcaacca attgatacac cgattcgtat tgatggagca
     9961 tcggcctatt ttagtagttt acctatcaaa gcgatggtac aagctatcaa aaaacaggga
    10021 cttccggcag ttgtatccaa tagtgcagga acctttgttt gcaatcattt gatgtaccaa
    10081 gctctttatt tagtggataa aaaattccct aatatgagag caggtttcat gcatattcca
    10141 tatatgatgg aacaagtagt aaataagccg aatactgcag gaatgagtct atgtgatatt
    10201 gtaagaggca tagaggtagc tattgaagct attgtagact acaaagataa ggatttgcag
    10261 ttagtaggcg gtgagactca ctgataacct aaaaaggata gtcaattatg cttgtttact
    10321 aactattaac tatgctaaat caattgaggt tgtttacata aaactctata tcagagaagc
    10381 ctgatataga gttttttctt gctagtttta ggattttctt gtaaaataga aaaagtgaag
    10441 agaggtatga aatgagcaag aaagataaaa aaatcgaaat tcaagtagcg gatgccaaag
    10501 ttaatgttgg taaagacagt tttgaaggtt atacattgac tatcggtaaa aaagttatcg
    10561 gagaaattgt cgaattagac ggacaatttg ccattataaa gaatgggaat gtcgatagtt
    10621 tttataaaaa attggaaaaa gctgtggaaa ttttgattga aaattataat ttagcaaaat
    10681 aagtcttgtt tttttgaaat tttcatgata taatagtcca tgttgattgt aggagagata
    10741 gcgaagaggc taaacgcggc ggactgtaaa tccgctcctt cgggttcggg ggttcgaatc
    10801 cctctctctc catttcatta atggggtata gccaagcggt aaggcaaggg actttgactc
    10861 cctcatgcgt tggttcgaat ccagctaccc cagttcttag gtaataatca agataaaaag
    10921 caaaatatct tagggtattt tatttttata attgaaagac gtgaatgata tgaacatgtc
    10981 cttgcgggtg cttaggaaaa aaattataag tatgtcaagt ttaagaaaaa cttgattgtt
    11041 ggaggatttt ttagatgaac gaatttgaag atttgctaaa tagcgttagt caagttgaga
    11101 ctggtgatgt tgttagtgct gaagtattga cagttgatgc gactcaagct aacgttgcaa
    11161 tctctggaac tggtgttgaa ggtgtcttga ctcttcgcga attgacaaac gatcgtgatg
    11221 cagatatcaa tgactttgtt aaagtaggag aagtattgga tgttcttgta cttcgtcaag
    11281 tagttggtaa agatactgat acagttacat accttgtatc taaaaaacgc cttgaagctc
    11341 gcaaagcatg ggacaaactt gttggtcgcg aagaagaagt tgttactgtt aaaggaacgc
    11401 gtgccgttaa aggtggactt tcagtagaat ttgaaggtgt tcgtggattt atcccagctt
    11461 caatgttgga tactcgtttc gtacgtaacg ctgagcgttt tgtaggtcaa gaatttgata
    11521 ctaaaatcaa agaagttaac gctaaagaaa accgcttcat cctttcacgt cgtgaagttg
    11581 ttgaagcagc tactgcagca gctcgcgctg aagtattcgg taaattggct gttggtgatg
    11641 ttgtaactgg taaagttgct cgtatcacaa gcttcggcgc tttcatcgac cttggtggtg
    11701 ttgacggatt ggttcacttg actgaattgt cacatgaacg taacgtatca ccaaaatcag
    11761 ttgtaactgt tggtgaagaa attgaagtga aaatccttga tcttaacgaa gaagaaggac
    11821 gtgtatcact ttcacttaaa gcaacagtac caggaccatg ggatggcgtt gagcaaaaat
    11881 tggctaaagg tgatgtagta gaaggaacag ttaaacgttt gactgacttc ggtgcatttg
    11941 ttgaagtatt gccaggtatc gatggacttg ttcacgtatc acaaatttca cacaagcgga
    12001 ttgaaaatcc aaaagaagct cttaaagttg gtcaagaagt tcaagttaaa gttcttgaag
    12061 ttaacgcaga tgcagaacgc gtgtcacttt ctattaaagc tcttgaagaa cgtccagccc
    12121 aagaagaagg acaaaaagaa gaaaaacgtg ctgctcgtcc acgtcgtcca agacgtcaag
    12181 aaaagcgtga tttcgaactt ccagaaacac aaacaggatt ttcaatggct gatttgtttg
    12241 gtgatatcga actttaatca aattgaaaat tcacaaaatc ctttgtttac taaacaaggg
    12301 atttttcttt tgtctctgct ccttttttga tataatagtt ctatgttaaa atcagaaaaa
    12361 caatcacgtt atcaaatgtt aaatgaagaa ttgtccttcc tattggaagg cgaaaccaat
    12421 gttttggcta atctttccaa cgccagtgct cttataaaat cacgttttcc taataccgta
    12481 tttgcaggct tttatttgtt cgatggaaag gaattggttt taggtccctt ccaaggaggt
    12541 gtttcctgca tccgtattgc actaggcaag ggtgtttgtg gtgaggcagc tcactttcag
    12601 gaaactgtta ttgttggaga tgtgacgacc tatctcaact atatttcttg tgatagtcta
    12661 gctaaaagtg aaattgtggt gccgatgatg aagaatggtc agttacttgg agttctggat
    12721 ctggattctt cagagattga ggattacgat gctatggatc gagattattt ggaacaattt
    12781 gtcgctattt tgcttgaaaa gacaacatgg gactttacga tgtttgagga aaaatcttaa
    12841 tgtatcaagc actttatcga aaatatagaa gtcaaaactt ctcccagtta gttggtcaag
    12901 aagttgtggc taagactctt aaacaagcgg tggagcaaga gaaaataagt cacgcttatc
    12961 ttttttctgg tcctcgtgga acgggaaaaa ccagtgttgc taaaatcttt gccaaggcta
    13021 tgaactgtcc caatcaagtg ggtggcgaac cttgcaataa ctgctatatt tgtcaagcag
    13081 tgacggacgg tagtttagaa gatgtcattg aaatggatgc agcttctaat aatggggtag
    13141 atgaaattcg cgaaattcgt gataaatcta cctatgcgcc tagccttgct cgttataagg
    13201 tttatatcat agatgaggtt cacatgctgt ctacaggggc ttttaatgcc ctcctaaaga
    13261 cgctggaaga accaacacag aatgtagtct ttattttggc cactactgaa ttgcacaaga
    13321 ttcctgctac tattctatcc cgtgtgcaac gttttgagtt taaatcaatt aagacacagg
    13381 atattaagga acatattcac tatatcttag aaaaagaaaa tatcagttct gaaccagagg
    13441 ctgtggaaat cattgccaga cgggcggaag gtggaatgcg ggacgccttg tctattttgg
    13501 atcaagccct gagtttgaca cagggaaatg agctgacgac tgctatctct gaagaaatta
    13561 ctggcaccat tagcctatca gccttggatg attatgtggc ggccttgtct caacaggatg
    13621 ttcccaaagc tttgtcttgc ttgaatcttc tttttgacaa tggtaagagc atgactcgtt
    13681 ttgtgaccga tcttttgcac tatttaagag acttgttaat tgttcaaaca gggggagaaa
    13741 atactcatca tagttcagtc tttgtagaaa atttggcact tcctcaaaaa aatctgtttg
    13801 aaatgattcg cttagcaaca gtgaatttag cagatattaa gtctagtttg cagcccaaga
    13861 tttatgctga aatgatgacc gtccgtttgg cggaaatcaa gcccgaacca gctctatcag
    13921 gagcggttga aaatgaaatt gctacgctga gacaggaagt tgcccgtctc aaacaagagc
    13981 tttctaatgc aggtgcggtt cctaaacaag ttgcaccagc tcctagtcga ccagctacgg
    14041 gcaaaacagt ctatcgtgtc gatcgcaata aagtgcaatc tatcttacaa gaggccgtcg
    14101 aaaatcctga tttagcacgt caaaatctaa ttcgtttgca gaatgcctgg ggagaggtaa
    14161 ttgaaagtct aggtgggccg gacaaggctc tgctagttgg ttctcaaccg gttgctgcca
    14221 atgaacacca tgctattctt gcttttgagt ctaacttcaa tgctggtcaa actatgaaac
    14281 gagacaatct caataccatg tttggtaata tcctcagtca ggcggcaggt ttttcacctg
    14341 agattttagc tatttccatg gaggaatgga aagaagttcg cgcagccttt tcagccaaag
    14401 ccaaatcttc tcaaactgaa aaagaagtag aagaaagcct gattccagaa ggatttgaat
    14461 ttttggctga taaagtgaag gtagaggaag actaaagaaa gatttcatga tacaataagt
    14521 ttatgaataa acaacaattt attattatgg cgctatttac agctgctgag acctattttt
    14581 tcaatgaagc ctggatgact ggccgctata ttatggcagc cttttgggca attttactct
    14641 ttagaaattt ccgagtcagt tatgtgatgg gtaaaattgt tgatgtcatc gatcagcatt
    14701 ttaataggaa agactagccc tcagcttcca gacaaaatca aagcctttta ggcttttttt
    14761 tgttatacta gaaaagtata tttatagaat ttttgctcta tttctgggga aatcagacgt
    14821 ttttctagta agtactgtaa aagttttgaa aaagaaagga actatcatgt cagtaataga
    14881 gatcaaagat cttcacgttg agattgaagg aaaagaaatt ttaaaagggg ttaacctgac
    14941 cctgaaaaca ggagaaattg ccgctatcat gggaccaaat ggtacaggta aatcgactct
    15001 ttctgccgct atcatgggaa atccaaacta tgaagtaact aaaggtgaag ttttgtttga
    15061 tggcgtaaac atccttgagt tggaagtgga tgagcgtgcg cgtatgggac ttttccttgc
    15121 tatgcaatac ccatcagaaa tccctggaat taccaatgct gagtttcttc gtgccgctat
    15181 gaatgcgggt aaagaagatg atgagaagat ttcagttcgt gagtttatta ctaagctaga
    15241 tgaaaaaatg gaattgctca acatgaaaga agaaatggca gagcgttacc tcaacgaagg
    15301 cttctctggt ggtgagaaaa aacgcaatga aattcttcaa cttttgatgt tggagccaac
    15361 atttgctctt ttggacgaga ttgactcagg tcttgatatt gacgctctta aagttgtgtc
    15421 taaaggtgtc aatgccatgc gtggtgaagg ttttggtgct atgatcatca ctcactacca
    15481 acgtcttttg aactatatca cacctgatgt ggtacacgtg atgatggaag gtcgtgttgt
    15541 cctttctggt ggtccagaat tggctgcgcg tttggaacgt gaaggatacg caaaattagc
    15601 tgaagaactt ggctacgact acaaggaaga attgtaattt cctcgtatct tttaggagaa
    15661 gtaaatgact agagaaaata ttaaactttt ttcagaaatg cacgctgaac caagctggtt
    15721 ggctgatctc cgtcaaaaag cttttgacaa gattgagact ttggaattac cagttattga
    15781 gcgtgtcaaa ttccaccgtt ggaatctggg tgatggaacg attacagaaa atgagccatc
    15841 agcaaatgtt ccagatttca cagctttaga tcatcacttg aagttggtgc aagtaggaac
    15901 tcaaactgtt ttcgaacaaa ctccagttga gttagctgaa cagggtgttg tcttcacaga
    15961 ctttcactca gctttagaag aaattccaga gctgatcgaa gaattcttca tgtcatctgt
    16021 taagtatgat gatgacaagt tggcggctta ccacacagct tactttaaca gtggtgctgt
    16081 actctatatt ccagataacg tagaaatcac agagccaatt gaaggaattt tctaccaaga
    16141 tagcgatagc aatgtgccgt ttaacaagca tattatgatt atcgctggta aaaattctaa
    16201 gattagttat ctggagcgtt tagagtcacg cggtgaagga agtgacaaag caactgccaa
    16261 tatcacagtg gaagtgattg cacattctgg tgcgcaagtc aagtttgctg ctatcgaccg
    16321 tctaggtgaa aacgtcactg cctacattag ccgtcgtggt aaattaggca acgatgcaag
    16381 tattgactgg gctatcggtg tcatgaacga aggaaatgtc gttgctgatt ttgatagtga
    16441 cttgattggt aatggtagct atgctgacct caaggttgta gctctttcaa gtggtcgtca
    16501 ggtacaaggg attgatactc gtgtaactaa ctatggctgc aactctatcg gaaatatcct
    16561 acaacatggg gttatccttg aaaaagcaac tttgactttc aatggtatcg gccacatcat
    16621 caagggtgct aagggagcag atgcccaaca agagagccgt gttctcatgc tttcagacca
    16681 agcgcgttca gatgctaacc caattctttt gattgatgaa aatgatgtca ctgcaggaca
    16741 cgcagcgtct atcggacaag ttgatccaga agacatgtat tacctcatga gtcgtggatt
    16801 ggataaggca actgcagagc gtttggttgt tcgtggtttc cttggatctg ttatcgtgga
    16861 gattccagtc aaggaagttc gtgatgaaat gattgcaact atcgaagaga aattgtcaaa
    16921 acgctaaggg gaagcctatg ttagatgtag aagcgattcg caaggatttt ccaattttag
    16981 atcagattgt caatgatgaa cctctggtct atctggacaa tgctgcgacg acacaaaaac
    17041 cactagtagt tctgaaagct attaacagtt actatgagca ggacaatgcc aatgttcacc
    17101 gtggtgtcca taccttagcg gaacgagcga cagcttctta tgaagctgct cgtgaaacca
    17161 ttcgtaagtt tattaatgca ggctctacaa aggaagttct ctttaccaga ggaacgacaa
    17221 ccagccttaa ctgggtggca cgctttgctg aggaaattct cactgaggga gaccaggtct
    17281 tgatttcagt aatggaacac cattctaata tcattccatg gcaggaagct tgtcgaaaga
    17341 ctggagcaga gcttgtctat gtctatctta aagacggtgc cttggatatg gaggatttgc
    17401 gagctaaatt gactgataag gttaaatttg tttccctagc tcatgcctcc aatgttcttg
    17461 gtgtggtcaa tccgatcaag gaaatcactc aattagccca ccaagttggg gcaatcatgg
    17521 tagtggatgg tgctcaatct acacctcata tgaagattga tgtccaggac ttggatctgg
    17581 actttttcgc cttttcgggt cacaagatgg ctggtccgac tggtatcggt gtcctttacg
    17641 gcaaagaaaa gtatcttgag caaatgtctc cagtagaatt tggcggcgag atgattgatt
    17701 ttgtctacga gcaatccgct agttggaagg aattgccttg gaaatttgag gctggaacgc
    17761 caaatatggc aggagctatt ggacttgcga ctgcagttga ttatctggaa aagattggta
    17821 tggatgccgt tgaagctcat gaacaggaat tgattgcgta cgtctatcca aaactgcagg
    17881 caattgaggg attgaccatt tacggttctc aggatttggc tcaacgttcg ggtgttattg
    17941 cctttaacct aggtgatctc catcctcacg atcttgcgac ggctctggat tatgaaggag
    18001 tggctgttcg tgctggtcac cattgtgcgc aacccttgct tcagtatttg gaagtctcag
    18061 caacagctcg tgcaagtttt tatatctata ataccaaggc agattgcgac aaactagtcg
    18121 atgccctaca aaagacaaag gagtttttca atggcacttt ctaaactaga tagcctttat
    18181 atggcagtgg tagcagacca ttcgaaaaat ccacatcacc aagggaagtt agaagacgct
    18241 gagcaaatca gtctcaacaa tccgacttgt ggagatgtca tcaatctctc tgtcaagttt
    18301 gatgcagagg accgtttgga agatattgct tttctaaatt caggatgcac gatttcaact
    18361 gcttctgcta gtatgatgac agatgccgtt ttaggaaaaa ccaaacaaga aattttagaa
    18421 ctggcgacta ttttttctga aatggttcaa gggcaaaaag atgagcgtca agaccaactt
    18481 ggagacgcgg cattcttgtc aggtgttgcc aaattccctc aaagaatcaa gtgtgcaacc
    18541 ctagcttgga atgcccttaa gaaaacaatt gaaaatcaag aaaaacagta agacaagttt
    18601 cttttgtctt atgaattatt agaaatgaag aaagaaagga tattatggct gaagaaagag
    18661 tagaaccaaa accaattgac cttggtgaat ataaatttgg tttccatgac gatgtagagc
    18721 ctgtcttatc gacaggaaaa ggactcaacg aaggtgttat tcgtgaatta tctgctgcta
    18781 agggtgagcc tgagtggatg ttggagttcc gtttgaagtc ttatgaaacc ttcaaaaaaa
    18841 tgcccatgca aacttgggga gcagacttgt cagagattga ctttgatgac ttaatctact
    18901 accaaaaacc atctgacaaa ccagcccgtt cttgggatga tgtacctgaa aagattaaag
    18961 aaacctttga acgtatcggg attccagaag ctgaacgtgc ttatttagca ggggcttctg
    19021 cccagtacga gtcagaagtg gtttaccaca acatgaagga agagttccaa aaattaggta
    19081 ttatctttac agatacagat tccgcactca aggaataccc agacttattt aatcaatact
    19141 ttgcgaagtt ggtaccgccg acagataaca agttggcagc cctcaactca gcagtatggt
    19201 cgggtggaac ttttatctac gtgccaaaag gtgtcaaggt agatattcca cttcaaactt
    19261 atttccgtat caataacgaa aatataggtc agttcgaacg taccttgatt atcgttgatg
    19321 agggagcaag cgtccactac gtagaaggat gtacagcacc aacatattca agcaatagct
    19381 tacacgctgc cattgtagaa atttttgctt tggacggagc ttatatgcgt tatacaacta
    19441 tccaaaactg gtctgataac gtctataact tggtaacaaa gcgtgctaag gctcaaaagg
    19501 atgccactgt tgagtggatt gatggaaact tgggtgccaa aacgactatg aaatatccat
    19561 ctgtttacct tgatggagaa ggagcgcgtg gtaccatgct ctctatcgcc tttgctaatg
    19621 cagggcaaca ccaagacacg ggtgctaaga tgattcacaa tgctccacat accagctcgt
    19681 ctattgtgtc taaatccatc gctaaaggtg gaggaaaggt tgactaccgt ggacaagtca
    19741 cctttaacaa gaactctaag aaatctgttt cccacattga atgtgatacc attatcatgg
    19801 atgacttgtc agcatcagat actattccat ttaatgaaat tcacaactcg caagtggctt
    19861 tggaacacga agccaaagta tctaagattt cagaagagca attgtattat ctcatgagcc
    19921 gtggattgtc agaatctgag gcaactgaaa tgattgtcat gggatttgta gaacccttta
    19981 caaaagaact tccaatggaa tacgcagttg agctgaaccg cttgattagc tatgaaatgg
    20041 agggatcagt tggataaaat ttgattttat actcttcgaa aatctcttca aaccacgtca
    20101 gcatcgcctt atcgtatgta tggttactga cttcgtcagt ttcatctaca acctcaaaac
    20161 agtgttttga gcaacctgcg gctagcttcc tagtttgttc tttgattttg aagatgaact
    20221 tgtatcaaaa aatcgcggtt taaaatcgcg attttttata atttctcgtt aacaaagcgg
    20281 acaaactgat tccaccaaac ttttaagaag aaggcttttt caattttctt gtctgctacc
    20341 atttcgaaac tagggcgctc tgtggtgatg taaccttgac caatcaagtc cttgtcttca
    20401 taagtcaaat ggccaaccac tgttccagct tcaagtggtg ctgggattgc tttggaatca
    20461 ggtgtgaatt gaacagattg agaagattga ttcccaacac gttcgattag atagatatcc
    20521 tctggagcca ctgcagttac tgtatcttct tttccatctt gtacaggggc tttgctatct
    20581 tgataggcat cgccttgttg aacgattttg cgaagtgtaa atgtagaaga aatataatcc
    20641 attagggaag atgtagctgt aaatcgagcg taaggattat tgtcttgatg atctgcattt
    20701 aaaacaactg tgatgactct catgcctttt tcgacagtag taccaacaaa agactctcca
    20761 gccttatctg ttgttcctgt ttttagccca tcaaaaccac cacggtaagc aggcatacct
    20821 tctaacatgt agttggttga agtgattgtc atcccagcaa aagtagaaga aggttttttg
    20881 gtgatttcta agacttgtgg gtattttttg atgaggttgc gagcaacgat agcgacatca
    20941 taagcactaa gcttattttc ctcatctttt ttagaacctg ggtaaatgtt atcccctaga
    21001 gtttcattgt taagacctgt cgtattgaca acagtggcat cctgaattcc ccattccaag
    21061 agttttgccc gcatcatatc gacgaaatct ttttctgagc cagcaatttt ctcagctagg
    21121 gcaatagcgg cgctgttggc actagatacc agagttgctt caagcaactc ttcgacagta
    21181 taattacggg cctccatagg aatattactg gcttcagaat ttgtcgtcaa ttgataagga
    21241 taatcagaaa tatctacagg agtggagagg gtaatacttc cgttttccaa agcttcatag
    21301 actagataaa cagtaatcaa ttttgttatg gaagcaattt cgacaggttg cgttgcatcc
    21361 ttctcataga gaattttacc agtatttgcc tcaacagcaa tcgcatgttt agcggcaatg
    21421 gtaaaatctt gagcaacagc agtagaaaca ccccctaaaa gagagacagt taacaaagtt
    21481 aaaaatattt ttttcatagt agtcttattc tatcataaag aaaaaaaata ttcttgcttt
    21541 aataattcat ctgttaagct ttttgaaaat atggtaaaat aaagtgaggg aggtaactca
    21601 tgtttcgtag aaataaatta tttttttgga ccacagaaat tttactctta accatcatct
    21661 tttacctatg gagacagatg ggatctttga ttaacccttt tgttagcgtg cttaatacaa
    21721 ttatgattcc atttttatta gggggctttc tttattattt gacaaaccct attgttactt
    21781 tcttaaataa agtctgtaaa ctcaatcgtt tgcttggtat tttaattacc ttgtgtactt
    21841 tggtctgggg aatggtcata ggtgttgtct atctcttacc tattttgatt aatcagttat
    21901 ctagtttgat tatatctagt caaactattt atagtcgagt acaagactta atcatagact
    21961 tatctaatta tcctgcgctc cagaatttgg atgtagaagc tacaattcag cagttaaact
    22021 tatcctatgt tgatattctt caaaatatcc taaatagcgt atcaaatagt gtggggagcg
    22081 tcttgtcagc tcttatcagt actgttttga ttttgattat gactccagtt tttttggttt
    22141 atttcttatt agatggacat aaattcttgc ccatgcttga aagaacgatt ctaaagaggg
    22201 atcgcttgca tattgcaggc ttattaaaga atttaaatgc gacgattgct cgctatatta
    22261 gtggagtttc gattgacgca atcattatag gttgtttggc ttatattggc tatagtatta
    22321 ttggtttaaa atatgcttta gtttttgcca ttttttctgg tgtagccaat ttaattcctt
    22381 atgtggggcc aagtattggt ttgattccta tgatcatcgc aaatatattc actgatcccc
    22441 atagactgct gattgcagtg atttatatgc ttgttgttca gcaggtagat ggcaatatct
    22501 tatatcctcg aattgtagga agtgttatga aggttcatcc aatcacgatt ttagttttac
    22561 ttttgttgtc aagcaatatc tatggtgtag ttggaatgat tgtcgcagtg ccaacctatt
    22621 ctatcttgaa agaaatttct aagttcttat cccgtttgta tgaaaatcat aaaataatga
    22681 aagaacgaga aagagaatta gctaagtaaa agtcaggaga accctgattt ttctttactg
    22741 gaagtggcct ttagattaga agactgaaaa taagttaaag tcttaaacta attttcacag
    22801 ctaagaatag tagaagttaa tctgataaaa atcgaaaaaa ccagtggaat tccgtgtcag
    22861 ggtaagttcc actggttttc atagtctatt aaagttcgaa tgaaacctat ttatagtata
    22921 ttgaaactag aatagtacac ctctaattct aaaacattgt tagaaatcga tttgactgtc
    22981 ctgatctatt cgtcctattc ttatttcatt ttactatatt ttggtgcaat aagtgaaaag
    23041 tagtccgaat aatataagga ttgattttat agtttttaaa ctcaaatgaa ttaaaataaa
    23101 gagagtacga aaattctcat ctgaaagtat tttagaataa ttctcttcgt gaatttcttc
    23161 aaaacagata gcttcatctt aggtatgtgt taattggatt tcgtaagctc tatttacaat
    23221 cgtaaagtta tgcactgaaa aagttgtagt tagtcttcca gtttgctaaa tttctcgaat
    23281 agtatctttt ttaggtatgt gatttctttt tgcatttttg agttagataa ggtataatgg
    23341 ttttattgtc ttttggggtc gttacggatt cgacaggcat tatgaggcat attttgcgac
    23401 tcgtgtggcg acgtaaacgc tcagttaaat ataactgcaa aaaataacac ttcttacgct
    23461 ctagctgcct aaaaaccagc aggcgtgacc cgatttggat tgctcgtgtt caatgacagg
    23521 tcttattatt agcgagatac gattaagcct tgtctagcgg cttgataaga gattgataga
    23581 ctcgcagttt ctagacttga gttatgtgtc gaggggctgt taaaataata cataacctat
    23641 ggttgtagac aaatatgttg gcaggtgttt ggacgtgggt tcgactccca ccggctccat
    23701 tattcctttg cattcttttg cattccttgg taaaacgttg ttaaatcaac gttttttatt
    23761 tttatctttg gtattccttt gcattctttt gctaaaaagg gagtcacaaa cagaccctat
    23821 tttaaaaaaa ggatagaaaa aaggatacaa catttgtcgc atcctaaaaa taatcttttt
    23881 tcgacggaag acatgggatt cgaacccacg cacgctatta cacgcctacc gcgtttccaa
    23941 cacggcctct taagcctctt gagtaatctt ccaatactta ctcaaatagt ctaccataaa
    24001 ggctcttatc ttgcaataaa aattctagaa ataagaaaaa tgatagattt tgaaagaaaa
    24061 tgataaaaaa tgcttgactt caaaagaaag tatgatagaa tgaatagtgt aaacgataac
    24121 aggaggtgat tcggtgttaa aaacagagcg gaagcaactg attttagagg agttaaatca
    24181 acatcatgta gtttctctag aaaaattagt tagtttgcta gaaacgtcag aatcaacggt
    24241 tcgaagagac ttggatgagt tggaagcgga aaacaagctt cgtcgtgtgc atggtggagc
    24301 agaactcccc cactccttac aggaagaaga aaccattcaa gaaaaatcgg tcaaaaacct
    24361 tcaagaaaag aagttgctgg ctcagaaagc agcctctctc attaaagaaa aagatgtcat
    24421 ctttatcgat gctggaacaa caactgcttt tttgattcat gaattggtca ataagaatgt
    24481 tacagttgtg accaactcca ttcaccatgc cgctcagttg gttgaaaagc agattccaac
    24541 tgtcatggtt ggaggaaacg tcaagacggc gacagatgct agtatcgggg gcgttgctct
    24601 taaccagatt aaccaattgc actttgaccg tgcctttatc ggaatgaatg gtgttgacga
    24661 tggctattat acgactcctg atatggagga gggagctgtg aaaagagcta ttttggagaa
    24721 tgccaagcag acctacgtct tggtggattc gtcaaaaatt ggacaaactt gctttgccaa
    24781 ggtagcacca ctcaaacgcg ctatcgttat cactagtcaa gggcatgagc tcttgcaggt
    24841 tattaaggag aaaacggagg taatagaagt atgatttata cagtcacact caatccatcc
    24901 attgactata tcgttcgttt ggaccaagtc aaagttggta gtgtaaatcg tatggacagt
    24961 gatgataagt ttgctggtgg gaaaggaatc aatgtcagcc gtgtcttgaa acgtttgaat
    25021 ataccaaata cagcgacggg atttatcggt ggctttactg gtaaatttat cacagatact
    25081 ttagcagagg aagaaatcga gacacgtttt gtccaggtgg cagaagatac tcgtatcaat
    25141 gttaaaatca aagcagacca agaaacagaa atcaacggaa cgggtccaac tgttgaaccg
    25201 gttcagctag aagaattgaa agctatttta tctagtctga cagcagaaga tacagttgtc
    25261 tttgcaggtt caagtgctaa aaatctaggc aatgttatct ataaggattt gatttccttg
    25321 acgcgccaga ctggtgcgca agtggtctgt gactttgaag gacagacctt aattgatagt
    25381 ttggactacc agcctcttct tgtaaaacca aacaatcatg aacttggagc gatttttggg
    25441 gttaaactcg aaagtttaga tgaaattgag aaatacgctc gtgagttact ggctaagggt
    25501 gctcaaaatg ttattatctc tatggctggt gatggcgccc ttcttgtcac atctgaggga
    25561 gcttacttcg ctaaaccaat caaaggaaca gtcaaaaatt cagttggagc tggtgattct
    25621 atggttgctg gattcacagg tgaatttgtc aaatcaaaag acgcagtaga agccttcaaa
    25681 tggggagtgg cttgcggaac ggcaactacc ttctcagatg acttggcaac ggcggaattt
    25741 attaaagaaa catatggaaa agttgaggta gaaaaaagat gaaaattcaa gacctattga
    25801 gaaaagatgt catgttgcta gatttgcagg caactgaaaa aacagctgtc atcgacgaga
    25861 tgattaaaaa tttgacagag cacggttatg taacagattt tgaaacattt aaagaaggaa
    25921 ttttggcgcg tgaagctttg acttctactg gtttgggtga tggaatcgca atgcctcaca
    25981 gcaaaaacgc tgctgtcaaa gaagcgacag ttctatttgc taagtcaaat aagggtgttg
    26041 actacgagag cttggatgga caagcaactg acctcttctt catgattgca gctccagaag
    26101 gtgccaatga tactcacttg gcagccttgg cagaattgtc tcaatacttg atgaaagacg
    26161 gttttgcaga caaacttcgt caagcaacat ctgcagacca agttatcgaa ctttttgacc
    26221 aagcttcaga aaaaactgag gaacttgttc aagcacctgc taatgactct ggtgacttta
    26281 tcgtagctgt tacagcttgt acaacaggta ttgcccacac ttacatggcc caagaagccc
    26341 ttcaaaaagt agctgctgaa atgggggttg gtatcaaggt cgaaaccaac ggtgctagcg
    26401 gtgttggaaa tcaactaact gcagaagata tccgtaaggc taaagctatt atcattgcag
    26461 cagacaaggc cgttgaaatg gatcgatttg atggaaaacc attgatcaat cgtccagttg
    26521 ctgacggtat ccgtaagaca gaagagctaa ttaacttggc tctttcagga gatactgaag
    26581 tctaccgtgc cgctaatggt gccaaagctg caacagcctc taacgaaaaa caaagccttg
    26641 gtggtgcctt gtacaaacac ttgatgagtg gtgtatctca aatgttacca ttcgttatcg
    26701 gtggtggtat catgattgcc cttgccttct tgattgacgg tgctttgggt gttccaaatg
    26761 aaaaccttgg caatcttggt tcttaccatg agttagcttc tatgttcatg aaaattggtg
    26821 gagctgcctt tggtttgatg cttccagtct ttgcgggtta tgttgcctac tctattgctg
    26881 aaaaaccggg tttggtagca ggtttcgtgg ctggtgctat tgccaaagaa ggttttgcct
    26941 ttggtaaaat tccttatgcc gcaggtggtg aagcaacttc aactcttgca ggtgtctcat
    27001 ctggtttcct aggtgccctt gttggtggat ttatcgcagg tgccttggtt cttgccatca
    27061 agaaatacgt taaagttcct cgttcactcg aaggtgctaa atcaatcctt ctattgccac
    27121 ttcttggaac aatcttgaca ggatttgtta tgctagctgt gaatatccca atggctgcaa
    27181 tcaacactgc tatgaatgac ttcctaggcg gtcttggagg aggttcagct gtccttcttg
    27241 gtatcgtcct tggtggaatg atggctgttg acatgggtgg accagttaat aaagcagctt
    27301 atgtctttgg tacaggtacg cttgcagcaa ctgtttcttc aggtggttct gtagccatgg
    27361 cagcagttat ggctggagga atggtgccac cacttgcaat ctttgtcgca actcttcttt
    27421 tcaaagataa atttactaag gaagaacgta actctggttt gacaaacatc atcatgggct
    27481 tgtcatttat cactgaggga gcgattccat ttggtgccgc tgacccagct cgtgcgattc
    27541 caagcttcat ccttggttca gcagtagcag gtggactcgt tggtcttact ggtatcaaac
    27601 tcatggcgcc acacggagga atcttcgtta tcgcccttac ttcaaatgct ctcctttacc
    27661 tcgtttctgt cttggtagga gcaatcgtaa gtggtgtggt ttatggttac ctacgcaaac
    27721 cacaagcata aaaaatagaa aaatgaaaag attggaccgt ttggtgcagt ctttttctct
    27781 tcccgaaatg cctgtgaaat atggtataat agaagaatgg caaacaagaa tacaagtaca
    27841 acaagacgga gaccgtctaa agcagaactg gaaagaaaag aagcgattca acgaatgttg
    27901 atttcgttag gaattgcgat tttattgatt ttcgcagcct tcaaattagg ggctgcaggt
    27961 ataacccttt ataatttaat tcgcttgcta gtgggtagcc tagcttatct ggcgatattc
    28021 ggcctattaa tctatctctt ctttttcaag tggatacgaa aacaggaagg actcttatct
    28081 ggctttttca ccatatttgc tggcttactc ttgatttttg aggcctactt ggtttggaaa
    28141 tatggtttgg acaagtccgt tctaaaaggg accatggctc aggttgtgac agatctgact
    28201 ggttttcgaa cgactagctt tgctggaggg ggcttgatcg gggtcgctct ttatattcca
    28261 acagcctttc tcttttcaaa tatcggaact tactttattg gttctatctt gattttagtg
    28321 ggttctctcc tagtcagccc ttggtctgtt tacgatattg ctgaattttt cagtagaggc
    28381 tttgccaaat ggtgggaagg gcacgagcgt cgaaaagagg aacgctttgt caaacaagaa
    28441 gaaaaagctc gccaaaaggc tgagaaagag gctagattag aacaagaaga gactgaaaaa
    28501 gccttactcg atttgcctcc tgttgatatg gaaacgggtg aaattctgac agaggaagct
    28561 gttcaaaatc ttccacctat tccagaagaa aagtgggtgg aaccagaaat catcctgcct
    28621 caagctgaac ttaaattccc tgaacaggaa gatgactcag atgacgaaga tgttcaggtc
    28681 gatttttcag ccaaagaagc ccttgaatac aaacttccaa gcttacaact ctttgcacca
    28741 gataaaccaa aagatcagtc taaagagaag aaaattgtca gagaaaatat caaaatctta
    28801 gaagcaacct ttgctagctt tggtattaag gtaacagttg aacgggccga aattgggcca
    28861 tcagtgacca agtatgaagt caagccggct gttggtgtaa gggtcaaccg catttccaat
    28921 ctatcagatg acctcgctct agccttggct gccaaagatg tccggattga agcaccaatc
    28981 cctgggaaat ccctaatcgg aattgaagtg cccaactccg atattgccac tgtatctttc
    29041 cgagaactat gggaacaatc gcaaacgaaa gcagaaaatt tcttggaaat tcctttaggg
    29101 aaggctgtta atggaaccgc aagagctttt gacctttcta aaatgcccca cttgctagtt
    29161 gcaggttcaa cgggttcagg gaagtcagta gcagttaacg gcattattgc tagcattctc
    29221 atgaaggcga gaccagatca agttaaattt atgatggtcg atcccaagat ggttgagtta
    29281 tctgtttaca atgatattcc ccacctcttg attccagtcg tgaccaatcc acgcaaagcc
    29341 agcaaggctc tgcaaaaggt tgtggatgaa atggaaaacc gttatgaact ctttgccaag
    29401 gtgggagttc ggaatattgc aggttttaat gccaaggtag aagagttcaa ttcccagtct
    29461 gagtacaagc aaattccgct accattcatt gtcgtgattg tggatgagtt ggctgacctc
    29521 atgatggtgg ccagcaagga agtggaagat gctatcatcc gtcttgggca gaaggcgcgt
    29581 gctgcaggta tccacatgat tcttgcaact cagcgtccat ctgttgatgt catctctggt
    29641 ttgattaagg ccaatgttcc atctcgtgta gcatttgcgg tttcatcagg aacagactcc
    29701 cgtacgattt tggatgaaaa tggagcagaa aaacttcttg gtcgaggaga catgctcttt
    29761 aaaccgattg atgaaaatca tccagttcgt ctccaaggct cctttatctc ggatgacgat
    29821 gttgagcgca ttgtgaactt catcaagact caggcagatg cagactacga tgagagtttt
    29881 gatccaggtg aggtttctga aaatgaagga gaattttcgg atggagatgc tggtggtgat
    29941 ccgctttttg aagaagctaa gtctttggtt atcgaaacac agaaagccag tgcgtctatg
    30001 attcagcgtc gtttatcagt tggatttaac cgtgcgaccc gtctcatgga agaactggag
    30061 atagcaggtg tcatcggtcc agctgaaggt accaaacctc gaaaagtgtt acaacaataa
    30121 aaaaatagct tctttccaag tttggaggga agctattttt ctggctattg attactttta
    30181 tactcttcgc aaatctcttc aaaccacgtc agcttcgcct tgccgtactc aagtactgtc
    30241 tacggctagc ttcctagttt gctctttgat tttcattgag tattattttc tgaagttgga
    30301 gtattgggct gtttttcatt ttcagtggca ggtttacttg tagcaggtgt agtagagtcc
    30361 tgagttgctg ttttctgatc ttcttttttc tcttccttga cgctagattt tggcgtttct
    30421 tcttgttgtg ttttttcttg agaagtgtta ttttccttat ttggagtagt attttcctga
    30481 ggggattctt tttgaatttc tttgacaaag gttgtcgtct ggcttgtcgt aggttctttt
    30541 ttagtatttt tattattatt atccaaggcg ttcatgatcg tgatacccgc ggtaatcaaa
    30601 ccaaggatac taccgatagt agtaatggtt ttttgaaaaa cagtaaagcc ttttttgata
    30661 tgttctgttt tcggttttga agttctacga tagttagaca tacattctct cctttgatta
    30721 tgatttatta tactctgttt ctttaaaaaa atcttaaaaa aagagaaatt gccctttctt
    30781 gtcgcaggct ccgtttcatg atacaataga aggagtgatt ttagaaagcg tgagaaacat
    30841 gatttacttt gataattcgg cgacgaccag gccctatcca gaagcccttg aaacctatat
    30901 gcaggtggct tcaaaaattt taggaaatcc atctagtctc catcgtttgg gagaccaggc
    30961 aacacgaatt ttagatgctt cccgtcaaca gattgcagat ttaatcggta agaaaagtga
    31021 tgaaatcttc tttacatctg gtgggacaga aggggataac tggatcatca agggagtagc
    31081 atttgaaaaa gcccagtttg gcaagcacat catcgtatca gccattgaac atccagcagt
    31141 taaggaatca gccctctggt tgaaagctca aggttttgaa gtggattttg ctccagttga
    31201 taacaaagga tttgtggatg ttgaggcgct agaagatttg ataagacctg atacgaccct
    31261 cgtttccatc atggctgtga acaatgaaat cggctctatc caacctattg aggctatttc
    31321 agaattcttg gcagacaagc caactatttc cttccacgtt gatgcggttc aggcgcttgc
    31381 caagattccg actgaaaagt atctgacaga acgagtggat ttcgcgactt tctctggtca
    31441 caagttccac ggaatccgtg gtgttggttt tatctatatc aagtctggca agaagattac
    31501 gcctctttta acaggtggtg gtcaggaacg tgattaccgt tcgacaactg aaaatgtggc
    31561 aggaattgca gcgaccgcta aggctctccg tttatctatg gaaaagctag atatctttag
    31621 gagcaagact gggcagatga aggcagtgat tcgtcaagca cttctggact atccggatat
    31681 atttgtcttt tcagatgagg aagacttcgc ccctcatatt ctgacttttg gaatcaaggg
    31741 tgttcgtggt gaggtcattg ttcacgcctt tgaagactat gatattttca tctcaacgac
    31801 ctcggcttgt tcgtccaagg ctgggaaacc agccggaacc ctgattgcta tgggagtgga
    31861 caaggataag gctcagtcag ctgtgcgtct tagtctagac cttgaaaatg atatgagtca
    31921 ggtcgagcag ttcttgacca agctaaaatt aatttacaat caaactagaa aagtaagata
    31981 ggagcattca tgcagtattc agaaattatg attcgctacg gtgagctgtc aaccaagggc
    32041 aaaaatcgta tgcgtttcat caataaactt cgcaataata tttcagacgt tttgtctatc
    32101 tatccccaag ttaaggtaac agcagatcgc gaccgtgccc acgcttacct caatggagca
    32161 gattacacag cagtagcaga atcgctcaaa caagtatttg gaattcaaaa cttttcccct
    32221 gtttataagg ttgaaaaatc tgtagaagtt ctgaagtctg ctgtccaaga gattatgcag
    32281 gacatctaca aggaaggcat gacctttaaa atctctagca agcgtagcga ccacaccttt
    32341 gaattggaca gtcgtgaact caaccaaacg cttggagggg ctgtattcga agccattcca
    32401 aacgtacaag ctcaaatgaa aagtcctgac atcaatcttc aggtggagat acgtgaagaa
    32461 gcagcctatc tttcttatga aaccgttcga ggggcaggtg gattaccagt gggaacttct
    32521 ggtaagggca tgctcatgtt gtcaggggga atcgattccc ctgtagctgg ctatctagcg
    32581 cttaaacgag gggtagatat agaggcagtt cactttgcca gcccacctta cacgagtcct
    32641 ggtgctctta aaaaagccca agatttgacc cgtaaattaa ccaaatttgg gggaaatatc
    32701 cagtttatcg aagttccttt tacagagatt caagaggaaa tcaaagccaa agcgccagaa
    32761 gcctacctta tgaccttgac gcgtcgtttt atgatgcgta ttactgaccg tattcgtgag
    32821 gtacgaaatg gtttagttat catcaatggg gaaagtctag gtcaagtagc cagccaaacc
    32881 cttgaaagta tgaaggctat caatgctgtt accaacactc ccatcattcg tcctgtggtt
    32941 accatggaca agttggaaat cattgacatc gcccaggaaa tcgatacctt tgacatttca
    33001 atccaaccgt ttgaagactg ttgtactatt tttgcaccag atcgtccaaa aacaaatcct
    33061 aaaattaaga atgcggagca gtacgaagcg cgtatggatg ttgaaggctt ggttgagcga
    33121 gcagtggctg gaatcatgat tactgaaatc acacctcaag ccgaaaaaga tgaagttgat
    33181 gacttgattg acaatctgct ctaattcaga aaatccaaaa gaatagcgaa aatcagtaaa
    33241 aaaagttagt tttttctcta aaaacaggta aaaaactaac tttttttatt tttatgatat
    33301 aatgatataa aattttgaat atagagagtt ttctgacaat gaatcaatcc tacttttatc
    33361 taaaaatgaa agaacacaaa ctcaaggttc cttatacagg taaggagcgc cgtgtacgta
    33421 ttcttcttcc taaagattat gagaaagata cagaccgttc ctatcctgtt gtatactttc
    33481 atgacgggca aaatgttttt aatagcaaag agtctttcat tggacattca tggaagatta
    33541 tcccagctat caaacgaaat ccggatatca gtcgcatgat tgtcgttgct attgacaatg
    33601 atggtatggg gaggatgaat gagtatgcgg cttggaagtt ccaagaatct cctatcccag
    33661 agcagcagtt tggtggtaag ggtgtggagt atgctgagtt tgtcatggag gtggtcaagc
    33721 cttttatcaa gcacaaaaca ggttggtttg atggcatgat gacgacaggt tgctctatgg
    33781 gagcctatca tgcactcaat ttcttcctcc agcatccaga tgtctttacc aaagtgattg
    33841 ctctcagtgg tgtttacgac gcacgtttct ttgtcggcga ttactacaac gatgatgcta
    33901 tttaccaaaa ctcgccagta gattatattt ggaaccaaaa cgatggctgg tttattgacc
    33961 gttaccgtca ggcagagatt gtgctgtgta cggggcttgg agcctgggaa caagatggtt
    34021 taccatcctt ttacaagctc aaagaagcct ttgaccagaa acaaattcca gcctggtttg
    34081 ctgaatgggg acatgatgtc gcccacgact gggaatggtg gcgtaaacaa atgccttatt
    34141 tcctcggtaa tctctattta taaaaggagt tacctatgaa ttaccttgtt atttctccct
    34201 actatccaca aaactttcaa cagtttacca tcgaactagc taataaaggc atcacagtct
    34261 tgggaattgg tcaagagtct tacgagcaat tggatgagcc cttgcgcaat agcttgaccg
    34321 agtattttcg tgttgataat cttgagaaca tagatgaagt caaacgtgca gttgcttttc
    34381 tcttttataa acatggtcca attgaccgca tcgagtctca caatgaatac tggcttgagc
    34441 tagacgcaac actcagagaa caattcaatg tttttggtgc caaaccagag gatctcaaaa
    34501 agacgaaata taagtctgaa atgaagaaac ttttcaaaaa agcaggtgtt cctgtggtac
    34561 ctggagctgt tatcaagacg gaagcagatg ttgatcaagc agtgaaagaa atcggtcttc
    34621 caatgattgc caaacctgat aatggagtgg gagcagccgc aacctttaaa cttgagacag
    34681 aagacgatat caatcacttc aagcaagaat gggaccattc aaccctttat ttctttgaaa
    34741 aatttgtcac ttccagcgaa atctgtacct ttgacgggct cgtggacaag gatggaaaga
    34801 ttgtcttctc aacaaccttt gactacgcct atacaccgct tgacctcatg atttataaga
    34861 tggacaattc ttattatgtg ctcaaggata tggatcctaa actgcgcaag tatggggaag
    34921 caattgtcaa agaatttggt atgaaagaac ggtttttcca tattgagttc ttccgtgagg
    34981 gggacgatta tattaccatc gagtacaata accgccctgc aggtggtttt accattgatg
    35041 tttataactt tgctcattcc ttggaccttt atcgtggcta tgcagctatt gtcgcaggag
    35101 aggagttccc ggcgtcagac tttgaaactc agtattgttt ggctacttct cgccgtgcaa
    35161 atgctcacta tgtttattca gaagaggatt tgcttgccaa atatagccag cagttcaagg
    35221 ttaaaaaagt catgccagct gccttcgcgg aacttcaagg agattacctg tatatgctga
    35281 caactccgag tcgacaagaa atggatcaga tgattgctga tttcggacaa cgtcaagaat
    35341 aagaactatc ggattaagga aattcactcc cttaatcctt ttgttttgtc tggtaaaaaa
    35401 taagagcatc ctaacaaggt agctatcata aaacttgttc gataactatt tgaagcagga
    35461 ttaggtggct agaaattgaa ttttaacatt tcaatttagt catagtattg tgttttcgta
    35521 tccttaaatc agctaaaagg atccatgacg acacctatac gatatagttt tcaggatacc
    35581 aaaccagtct attaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt
    35641 tgctcaaaac actgttttga ggttgtggat agaactgaca gagtcagtat catataccta
    35701 cggcaaggtg aagctgacgt ggtttgaaga gattttcgaa gagtataaaa tattcaggtg
    35761 acgcatagat atagttaatt gaagctttgt ttgaaatctg ataaaataat gatattacta
    35821 agttttaaaa actaaagaaa agggaagata tgattacagg cgaattaaaa aataaaatcg
    35881 atcagctgtg ggaaattctt tggacagaag gaaacgcaaa tcctttaaca aatattgaac
    35941 agttgactta tctcttattt atgaaagatt tggatagtgt cgagcttgga cgtgaaagtg
    36001 atgctgaatt tctagggatt ccttatgagg gagtttttcc aaaagataaa cctgaatacc
    36061 gttggtcaac ttttaaaaat ataggagatg ctcaggaagt ttatcgttta atgactcagg
    36121 agatttttcc gtttattaaa aatctcaagg gggatacaga tgatacagcc ttttcacgat
    36181 atatgcgaga agctattttt caaataaata aacctgctac gcttcaaaag gcaatttcta
    36241 tcttagatgt ttttccaact aggggattag atgtagattt tgataatgac aaacaaagta
    36301 ttactgatat cggagatatc tatgaatatc tgttatcaaa attgtcgacc gcaggtaaaa
    36361 atggacagtt ccgtacacct cgtcacatca tcgatatgat ggttgagttg atgcaaccga
    36421 ctatcaaaga tatcatctca gatcccgcta tgggttctgc tggcttctta gtatctgcta
    36481 gccgttactt aaagcgtaag aaagatgaat gggaaaccaa tacagataat atcaatcatt
    36541 ttcataatca gatgtttcat ggaaatgata cggatacgac tatgttgaga cttggggcga
    36601 tgaacatgat gctacatgga gtagaaaatc cacaaatcag ttaccttgac tcgctgtctc
    36661 aagataatga agaagccgat aaatatactt tggttttagc aaatcctcct tttaagggct
    36721 cacttgacta caattcaacc tctaatgacc ttcttgcaac cgtaaaaacc aaaaaaacag
    36781 aattactctt tctttctctt ttcttgcgaa ctttaaaacc aggtggacga gcagcagtta
    36841 tcgtacctga tggtgtcctt tttggttcgt ctaaagctca taaaggaatt cgtcaggaaa
    36901 ttgtagagaa tcataagctt gatgctgtaa tctcaatgcc tagtggtgtg ttcaagcctt
    36961 atgctggagt ttcaactgcc attctcatct ttacaaaaac tggtaatggt ggtactgaca
    37021 aagtctggtt ttacgatatg aaagcggatg gtttaagttt ggatgataag cgacaaccga
    37081 ttagcgacaa tgatattcca gatattatcg aacgctttca tcatcttgaa aaagaagcag
    37141 aacgtcagag aacggatcaa tctttctttg ttccagttgc tgagataaag gaaaatgatt
    37201 atgatttgtc tatcaataaa tataaagaga ttgagtatga aaaagttgag tatgaaccaa
    37261 cagaggtcat cttaaagaaa atcaatgatt tagaaaaaga aattcaagct ggcttggctg
    37321 aattagaaaa attactcaag tagggaggtg gctgtatgaa aaaagtgaag ttgggggaag
    37381 tcttatctct aaaaaaaggc aagaaagcca ctgtacttgc tgaacaaaca actctaagcc
    37441 aacgttatat tcaaatagat gatttaagaa ataataataa tttaaaattc actgaaagtt
    37501 taaatatgac tgaagcactc ccagatgata ttctgatagc atgggatgga gctaatgcag
    37561 gaacagttgg ttatggatta tcgggagctg ttggtagtac aattacggtc ttaaaaaaga
    37621 atgagcgata caaagaaaaa attatatcag attacttggg agtctttttg gaaagtaaat
    37681 cgcagtattt acgagaacat tcaacaggtg caacaattcc tcatttaaac aagaatatat
    37741 tacttgattt acaattagaa ttgctaggta tcgaagaaca agagaacatt atctgtattc
    37801 ttaatacgat taaagggctt attactaaaa gaaaattgca gttagatgaa ctaaacttgc
    37861 tcg
//
LOCUS       DAVBNZ010000016        35498 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000016 DAVBNZ010000000
VERSION     DAVBNZ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.016"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(1..175)
                     /locus_tag="VQ860_000839"
                     /pseudo
     CDS             complement(1..175)
                     /locus_tag="VQ860_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            161..646
                     /locus_tag="VQ860_000840"
     CDS             161..646
                     /locus_tag="VQ860_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET3119291.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            730..1437
                     /locus_tag="VQ860_000841"
     CDS             730..1437
                     /locus_tag="VQ860_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3119292.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGKQEGDDSDNIADNSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1438..2769
                     /locus_tag="VQ860_000842"
     CDS             1438..2769
                     /locus_tag="VQ860_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET3119293.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2936..3811
                     /locus_tag="VQ860_000843"
     CDS             2936..3811
                     /locus_tag="VQ860_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET3119294.1"
                     /translation="MKFKKILTLAAIGLSGFGLVACGNQSSTSKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3929..4792
                     /gene="pstC"
                     /locus_tag="VQ860_000844"
     CDS             3929..4792
                     /gene="pstC"
                     /locus_tag="VQ860_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3119295.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4785..5600
                     /gene="pstA"
                     /locus_tag="VQ860_000845"
     CDS             4785..5600
                     /gene="pstA"
                     /locus_tag="VQ860_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3119296.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5602..6354
                     /gene="pstB"
                     /locus_tag="VQ860_000846"
     CDS             5602..6354
                     /gene="pstB"
                     /locus_tag="VQ860_000846"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3119297.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6369..7019
                     /gene="phoU"
                     /locus_tag="VQ860_000847"
     CDS             6369..7019
                     /gene="phoU"
                     /locus_tag="VQ860_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3119298.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            7087..7512
                     /locus_tag="VQ860_000848"
     CDS             7087..7512
                     /locus_tag="VQ860_000848"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3119299.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(7686..8066)
                     /locus_tag="VQ860_000849"
     CDS             complement(7686..8066)
                     /locus_tag="VQ860_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3119300.1"
                     /translation="MREFGEKIKRLRLAIKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            8278..9294
                     /locus_tag="VQ860_000850"
     CDS             8278..9294
                     /locus_tag="VQ860_000850"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3119301.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9316..10215
                     /gene="galU"
                     /locus_tag="VQ860_000851"
     CDS             9316..10215
                     /gene="galU"
                     /locus_tag="VQ860_000851"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET3119302.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            10633..11565
                     /locus_tag="VQ860_000852"
     CDS             10633..11565
                     /locus_tag="VQ860_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119303.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDDKFKDKATLENNVKEINKQIDFIKKVDETFKQKKLDE
                     TVKSLTDIADKFQKQIDVLKKEEEQKASDKAKEDKKKEESTSSQSSNSSSQASSSSFS
                     SYSGNSDYAPEQTYTADNSQSYSGSTGGDNSNYKAPAATDNGGNDGYILGHVTGADGS
                     QRDFYFNRSNGDVRDTSGNHVGNFGGGITDFRQR"
     gene            complement(11668..12345)
                     /locus_tag="VQ860_000853"
     CDS             complement(11668..12345)
                     /locus_tag="VQ860_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET3119304.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGL"
     gene            complement(12329..12868)
                     /locus_tag="VQ860_000854"
     CDS             complement(12329..12868)
                     /locus_tag="VQ860_000854"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET3119305.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVVYDPQQLVKTAFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(12880..14010)
                     /locus_tag="VQ860_000855"
     CDS             complement(12880..14010)
                     /locus_tag="VQ860_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET3119306.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFVGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITETAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(14078..14776)
                     /gene="dapD"
                     /locus_tag="VQ860_000856"
     CDS             complement(14078..14776)
                     /gene="dapD"
                     /locus_tag="VQ860_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET3119307.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGSVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(15006..15917)
                     /locus_tag="VQ860_000857"
     CDS             complement(15006..15917)
                     /locus_tag="VQ860_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3119308.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSIVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(15982..18447)
                     /locus_tag="VQ860_000858"
     CDS             complement(15982..18447)
                     /locus_tag="VQ860_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3119309.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYSLLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            18589..19845
                     /locus_tag="VQ860_000859"
     CDS             18589..19845
                     /locus_tag="VQ860_000859"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET3119310.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(19923..21986)
                     /locus_tag="VQ860_000860"
     CDS             complement(19923..21986)
                     /locus_tag="VQ860_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3119311.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGSGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLTRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(21988..22266)
                     /locus_tag="VQ860_000861"
     CDS             complement(21988..22266)
                     /locus_tag="VQ860_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119312.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            22418..23266
                     /locus_tag="VQ860_000862"
     CDS             22418..23266
                     /locus_tag="VQ860_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3119313.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            23888..24460
                     /locus_tag="VQ860_000863"
     CDS             23888..24460
                     /locus_tag="VQ860_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119314.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(25504..27762)
                     /gene="glgP"
                     /locus_tag="VQ860_000864"
     CDS             complement(25504..27762)
                     /gene="glgP"
                     /locus_tag="VQ860_000864"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET3119315.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVCSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(27788..29305)
                     /gene="malQ"
                     /locus_tag="VQ860_000865"
     CDS             complement(27788..29305)
                     /gene="malQ"
                     /locus_tag="VQ860_000865"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET3119316.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGYVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            29855..31126
                     /locus_tag="VQ860_000866"
     CDS             29855..31126
                     /locus_tag="VQ860_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3119317.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKITLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            31237..32529
                     /locus_tag="VQ860_000867"
     CDS             31237..32529
                     /locus_tag="VQ860_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3119318.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            32531..33373
                     /locus_tag="VQ860_000868"
     CDS             32531..33373
                     /locus_tag="VQ860_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3119319.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            33626..34426
                     /locus_tag="VQ860_000869"
     CDS             33626..34426
                     /locus_tag="VQ860_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET3119320.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQTPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            34436..35422
                     /locus_tag="VQ860_000870"
     CDS             34436..35422
                     /locus_tag="VQ860_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3119321.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNGNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
BASE COUNT        10859 a         7492 c         6675 g        10472 t
ORIGIN      
        1 cttcatagcg tggcatttct ttttaccaga atcattcgct aattcttctt ttagggcgat
       61 tgatttgtac ttccgtcgca tcaatcatta ccgtgtcctc agaactgaga ggagttcttg
      121 aaatcgtaaa accactttga acaagagtta cttcaaccca ttggctccga cggataaaga
      181 agacttgata agaactctag agttagctcc ccatgttgaa ggtggctatt ttagacaaac
      241 aaaaaaagct tcagacacta taaaccttgc tggtaaggga agggcgcttt ataccagtat
      301 ttatttctta ttagaagaaa cgaatccttc acattttcac cgattgacag cagatgaaat
      361 ctggtatttt catgcagaat ccccacttac tgttcacatg attacagcag atggtcacta
      421 cgaagcagtc actttaggcc tggacatatc caaagggcaa caacttcact actgtgttcc
      481 taagggcact atttggggat caacagttga taaggatgat gctctggttt cttgtcttgt
      541 tgctcctggt tttgaatttg aggattttga attatttgaa agggtagatc tactggcgac
      601 ctatccagag cacaaggaga tgattgagcg tttgaccaga tactagtctt tataagcaaa
      661 tttaatctga tttagcaatg ttaggatttc tgataattgt gttataatgt taccaatagg
      721 agataataga tgacaaaaca agtcttatta gtggatgatg aagaacacat tctgaaattg
      781 cttgactacc atttaagtaa ggaaggcttt tctactcaat tggtaacaaa tggacggaag
      841 gccttagctt tggcagaaac agaacccttt gattttatct tgcttgatat catgttacca
      901 caattagatg gcatagaagt ttgtaagcgg ctgagagcca aaggcgtcaa aactccaatt
      961 atgatggttt ctgcgaaaag tgatgaattt gataaggttt tggccttgga attaggggct
     1021 gatgactacc tgaccaagcc ttttagccct agagaattac tggcgcgtgt caaggctgtc
     1081 ctcaggcgaa ctaaaggaaa acaagaagga gatgattcag ataatatcgc tgacaattct
     1141 tggctatttg ggaccttgaa agtataccct gagcgtcatg aagtctacaa ggcgaataag
     1201 ttactgagtt tgaccccaaa agaatttgaa ctcttgctct atcttatgaa acatcccaac
     1261 atgacactga ctagagagcg tcttttggaa cgtatctggg ggtatgactt tgggcaggaa
     1321 acacgtttgg tggacgttca tattggtaag ttgagggaaa aaattgaaga caatcctaaa
     1381 gcccctcaat ttattcgaac cattcggggt tatggttata agttcaagga gttatagatg
     1441 aaacgctacc ttcaattttg gctagtcaat ctaagtgtta gcctcattct gattgcaggg
     1501 atggcattaa cttggatcag taaaggcatc ggtctctttc ttctagccct ttctttggga
     1561 ctaggtggct actggctctt ttgcctttgg aaatgggaag ttgcttttga gaccttgcac
     1621 caacctctct tgaccagtag tgaatacttt ttagaaaaag ggcaagaaga cttaaagtct
     1681 ttggctcagt atgtgtctgg cctaaaaacc aaagtctccc aacaggatca gcaatacaag
     1741 gacctagccg aaacaatgga ggttcttctg tcgcacctaa ccatggggac gtttttagtt
     1801 tccgctcaag gtcagatgtt attatccagt cgctctctgc ctcattattt tcccgatgtg
     1861 gacggcgaca taagttcact tgatgacctc aaacggatgg atattcggaa tttagttcac
     1921 caagcctttg atcaaaaaac aaggttaaaa caagaagtaa gtgggtttca tgagggtgac
     1981 ttgattttag aagtgacagc agttcccgtt tttagcccca cccaatctgt ggaagctgtg
     2041 ctcgtcttgc tatatgattt aacaacgatt agaacttatg aaaagttaaa tttagccttt
     2101 gtctcaaatg cctcccatga attgaggaca ccagttactt cgattaaggg ctttgctgaa
     2161 accattaagg ggatgtcagc tgaagaagaa gcgctcaagg atgactttct agacattatt
     2221 tacaaagaaa gcttgcgtct tgagcatatt gttgagcatc ttcttacctt atctaaggct
     2281 caacaaatgc ctatacaatg gacgaccctt tctttggcag aatttgtaca ggatttgact
     2341 caaagcttgc aacctcagct caagaagaag gatttacagc taaaggtgca ggtgccagat
     2401 gatgtcaccc tcgtatcaga tagtcaatta ctttcccaaa tcttactcaa tcttttatcc
     2461 aatgccatcc gttacactga acaaggggga aaaattgagg tcaagaccca aaaggtgaac
     2521 gaaggcatta agatttctgt atcagataca gggattggta ttagtcaatt agagcaggat
     2581 cgtatttttg aacgttttta ccgagttaat aaaggtcgaa gcagacaaac tggtggcact
     2641 ggtcttggcc ttgccattgt caaagaactc agtcaattat taggtggcca agtcacggtg
     2701 acgagtcagc ttggcagagg cagttgcttc acgatttttc ttcctaacca atctttcgca
     2761 caggactaat aatttttaaa gctattttta ggagcagcca tttttcaaaa gtggcttttt
     2821 ttgattcttt acacaatctt tacatgaatc agggataaac ctttacaaag acttgttaga
     2881 ctataaatgt agtaagccta cacaagaaaa atacatagag ataaaggtga ttattatgaa
     2941 attcaaaaaa atacttactc ttgcagccat tggcttatca ggatttgggc ttgttgcctg
     3001 tggcaatcag tcatctactt ccaaacagtc agcttcagga acgattgagg tgatttcacg
     3061 agaaaatggc tctgggacac ggggtgcctt cacagaaatc acagggattc tcaaaaaaga
     3121 cggtgataaa aaaattgaca acactgccaa aacagctgtg attcaaaata gtacagaagg
     3181 tgttctctca gcagttcaag ggaatgctaa tgctatcggc tacatctcct tgggatcttt
     3241 aacgaaatct gtcaaggctt tagagattga tggtgtcaag gctagtcgag acacagtttt
     3301 agatggtgaa taccctcttc aacgtccctt caacattgtt tggtcttcta atctttccaa
     3361 gctaggtcaa gattttatca gctttatcca ctccaaacaa ggtcaacaag tggtcacaga
     3421 taataaattt attgaagcta aaactgaaac cacagaatat acaagccaac acttatcagg
     3481 caagttgtct gttgtaggtt ccacttcagt atcttcttta atggaaaaat tagcagaagc
     3541 ttataaaaaa gaaaatccag aagttacgat tgatattacc tctaatgggt cttcagcagg
     3601 tattaccgct gttaaggaga aaaccgctga tattggtatg gtttctaggg aattaactcc
     3661 tgaagaaggt aagagtctca cccatgatgc tattgcttta gacggtattg ctgttgtggt
     3721 caataatgac aataaggcaa gccaagtcag tatggctgaa cttgcagacg tttttagtgg
     3781 caaattaacc acctgggaca agattaaata aaatgtttgc tccataaatc tctaaagaga
     3841 tgcagacgtt tcatcgtaca ataagataaa gaaggcaagt agggaggtgt cgtatctccc
     3901 ttactttctt cactagaaag gacaagatgt gacaaaacaa gccttcaaag aagcagtttt
     3961 tagggcaatt tttttcatga gtgcaacagt agctgttgta gctattttgc taatctgttt
     4021 ctttattttt agtaatggct tacctttcat ggctaactac ggctttgccc gttttttatt
     4081 aggcagtgat tggtcgccaa cgaacattcc ggcaagctat ggtattttac caatgatcgt
     4141 tggttcctta ttaattacct taggagcgat tgtgattggg gtgccaacag gcatcttgac
     4201 atcggtgttt atggtttatt attgtccaaa gcccgtctat ggcttcttaa aatcagctat
     4261 caacttgatg gcagccattc catctattgt ttatggtttt ttcggcctac aattattggt
     4321 gccttggatt agaacctttt taggaaatgg catgagtgtc ctaaccgctt cgttactatt
     4381 aggaataatg attttgccaa ccattatcag tttgtcagaa tctgctatcc gaacagttcc
     4441 caaaacgtat tattctggta gcttggctct aggagctagt catgaacgga gtatttttag
     4501 tgtcatcttg ccagctgcga gatctggtat tttatcagca gttattttag gaatcggtcg
     4561 cgcagtaggt gaaaccatgg cagttatttt ggtggcaggc aaccagccaa ttattccaag
     4621 tggactcttt tcaggaacca gaaccttaac aaccaatatt gttctggaaa tggcttacgc
     4681 atcaggtcag catagggaag cccttattgc aacctcagca gttctctttt tccttattct
     4741 cttgattaat gcctactttg cctacttgaa aggaaaatca tcttatgagt aaatacctgc
     4801 taaaacttct cgtttattgt ttttcagctt taacctttgg ctctctcttt ttaatcattg
     4861 gttttatcct catcaaaggc ttacctcatc taagtctatc cctcttttct tggacttata
     4921 cttctgagaa catttccctt atgccagcga ttatttccac cgttattctg gtttttggtg
     4981 ctcttctttt agctttgccc atagggattt ttgctggttt ttatcttgtg gaatatacaa
     5041 aaaaagattc cctttgtgtt aaaatcatgc gattggcctc agataccttg tctgggattc
     5101 cttccattgt ttttggtctg tttggcatgc tcttctttgt agtcttctta ggttttcaat
     5161 actctctgtt atcaggaatc ttaacctcag ttatcatggt gttgccagtc attattcgct
     5221 caacagaaga agccctttta tctgttagtg atagcatgcg tcaagcaagt tatggacttg
     5281 gggcaggtaa gttacggact gtttttagaa ttgttctacc agttgccatg ccaggtattt
     5341 tagctggagt gatactagct attggccgta tcgttggtga aacagctgcc ctcatgtata
     5401 cattaggtac ctctaccaat acgccaagta gtctcatgtc ttcaggccgt tctctagccc
     5461 tacatatgta tatgctgtca agtgaggggc tacatgtcaa tgaagcctat gctaccggcg
     5521 tgattttaat tattactgtt ttaatgataa atactctatc aagcttatta tctcggaaac
     5581 ttgtgaaagg agcttcctag tatgggaaca ttttcagtca gacacctaga cttattttac
     5641 ggggattttc aagccttaaa aaatatttcg attcaattac cagaaagaca gattactgcc
     5701 ttgataggcc catctggttg tggcaaatca acttttctaa aaacccttaa ccggatgaac
     5761 gatttggttc cttcttgcca tattgaaggc caagtcctct tagatgagca agatatttat
     5821 agtagcaaat tcaaccttaa tcagctacgt aagcgtgtag ggatggtttt tcaacagcct
     5881 aatccctttg ccatgtctat ctatgataac gtggcttatg gcccaaggac acatggtatt
     5941 cgagacaaaa aacaattaga tgccttagtg gagaaatctt taaaaggggc agccatttgg
     6001 gaagaagtca aagatgatct taaaaagagt gccatgtcct tatctggcgg tcagcagcaa
     6061 cgcctttgca ttgcgcgagc tttagcagta gaacctgata ttctgttaat ggatgagccg
     6121 acttcagcct tagaccctat ctccacttta aaaattgaag acctcattca gcaactaaaa
     6181 aaagattata cgattatcat tgttacccat aacatgcaac aagcttcacg tatttcagat
     6241 aaaactgctt ttttcttaac aggagaaatt tgcgaatttg gagataccgt tgacgtgttt
     6301 accaatccaa aagatcagcg cacagaagac tatatttcag gacggttcgg ataaggaagg
     6361 aaaaacctat gagaaatcaa tttgacttag aattgcatga attagaacaa tcctttttag
     6421 gactagggca acttgtcctt gaaacagctt caaaagcctt actggcctta gcctccaaag
     6481 acaaggagat ggcagagcta attatcaata aggatcatgc tatcaaccaa ggtcaaagcg
     6541 ctatcgaatt gacctgtgcc cgtttgttgg ccttgcagca gccacaagtg tctgaccttc
     6601 gatttgtgat tagcatcatg tcttcttgtt cagaccttga acgtatggga gaccatatgg
     6661 caggcattgc caaagctgtt ttgcaactaa aagaaaatca actagcccct gacgaagaac
     6721 agttacacca aatgggtaaa ttatccctca gcatgctatc cgatttattg gttgcctttc
     6781 ctttgcacca agcctcaaaa gctattagta ttgctcaaaa agatgaacag attgaccaat
     6841 attattatgc cttatcaaag gaaatcattg gacttatgaa agaccaagaa acctcaattc
     6901 ccaatggaac acaatacctt tatatcatag ggcatctgga acgcttcgct gattacattg
     6961 ctaacatttg tgaacgccta gtctacctag aaacaggaga actagtggat ttgaattaat
     7021 tcaactaatc cttaaaagag aagagtacga ttaagtgctc ttttttatgg ttgtaaaaaa
     7081 gttcatttga ccaatttaag cagtgtagat agtgaggagc tgtttcaatt ctatcgtgaa
     7141 cgagggaatg ctgaaaactt tatcaaagaa aggaaagcag gattctttgg ggataagaca
     7201 gatagttcga ccatgattaa gaatgaagta cgtatgatga tgggctgtct ggcttataat
     7261 ctctacctct ttttaaagca gctagctggt gatgaagtaa aggccttgac tatcaagcgt
     7321 tttcgacgtc tcttccttca tattgccgga aaatatgtct ctactgctag acgacatatt
     7381 ctcaaattct caagtctata tgcctattca aaacagtttc aagccttatt tgatacaatc
     7441 tgccagataa atctgatact ccctgttcca tatagagcta gagggcaggg gaaaacatgc
     7501 ctaacagaat aagtcacctt attttaaaaa tcgagcatca aaccaaggga ggagtctgcc
     7561 cttttttagg aaaaaatcaa gacaaatctc ctcaattatg tctctaacat cagaaattaa
     7621 gcaaaatcac cagaaggaca gtatttcaac tagcttttct ggtaattttt gaactgtgta
     7681 gttcgttagt gccagatatg aataatttgg gatgataaat ctttcttcct caggtagcct
     7741 atcataatac tcttcaaaaa tcttatcaaa acactctctt tcttttgggc gatagtttca
     7801 tcttcgtatg taggagtcct catcaagaaa tacttcaatt ctaggtattc cttatccaac
     7861 tctatataac ttggcatcaa cttgtaatcc tcaaccccca aacgttcagc gatatatttt
     7921 aactttgtta gtgttggtct ggattctcca ttttcaattc taattaattg acggatactt
     7981 aattcagact catcaccaca aaattctgaa cgactgattt ttatagccaa acgtaatctt
     8041 ttaatttttt cgccaaactc tcgcaaccta caagaacctc ctgagttgtt tacctctatt
     8101 ataagcatat actgaatcaa actatctatc agatttcttc tcactttaac taaagactaa
     8161 gagtttatcc cttcatctcg gtctttgtgt atttttccac cataccccag taatgcaagt
     8221 gcaaaatcct ctagaatatg atagaataat ggaaagaact ctatcaagga ggaaatcatg
     8281 gaaaaacaaa ccgtcgccgt cttggggcct ggttcttggg gaactgccct ttcacaagtc
     8341 ttaaatgaca atggacacga ggtacgtatt tggggaaatc ttcccgagca aatcaatgaa
     8401 attaatacct atcatactaa caagcactac tttaaagatg tcgttctaga tgaaaatatc
     8461 attgcctaca ccgacttagc agaaacattg aaagatgtgg atgcgatttt gtttgttgtc
     8521 ccaacaaaag tgacacgact tgttgcccaa caagttgcac aaaccttgga ccataaggct
     8581 atcatcatgc acgcttcaaa gggattagaa cctgatagcc ataaacgatt atcaactatc
     8641 cttgaagaag aaattcctga acagctccgc agtgatattg tcgttgtttc agggcctagt
     8701 catgcggaag aaaccattgt gcgtgaccta actttaatca ctgctgcttc taaagattta
     8761 caaacagctc aatacgttca ggagctattt agtaatcact acttccgact ttataccaat
     8821 acggatgtta tcggggttga aactgctggt gctcttaaaa atattattgc tgtcggtgct
     8881 ggagctttac atggtcttgg atttggtgat aatgctaagg cagccatcat cgctcgaggt
     8941 ttagcagaaa tcacccgcct aggggtagca ctcggggcca gtccattgac ctatagcggc
     9001 ttatctggtg tgggagattt gatcgtaacg ggaacttcca tccactctcg taactggaga
     9061 gctggagatg ctctcggacg aggagaatcc ctagctgata tagaagctaa tatgggcatg
     9121 gtaatcgaag gaatttcaac gactcgagca gcctatgaac tagcccaaga acttggagtc
     9181 tatatgccca ttacacaggc tatttaccaa gttatttatc acggaaccaa tatcaaagat
     9241 gccatttatg acatcatgaa caatgaattt aaagcagaaa atgagtggtc ttaaccctct
     9301 atagaaagga tttttatgac atcaaaagtt agaaaggcag tcatccctgc tgctggacta
     9361 ggaactcgat ttttaccagc aaccaaggcc cttgccaaag aaatgttgcc aatcgtagac
     9421 aaaccaacta tccagtttat cgtggaagag gctctcaaat caggtattga agatattcta
     9481 gttgtcactg gtaaatcaaa acgttctatt gaggaccact ttgattcaaa cttcgaattg
     9541 gaatataacc tcaaagaaaa agggaaaaca gatcttttga agctagttga tgaaacaact
     9601 ggcatgcgtc tgcattttat ccgccaaact catccacgcg gtctcggaga tgctgttttg
     9661 caagccaagg ctttcgtcgg aaatgaacct tttgtcgtta tgcttggtga tgacttgatg
     9721 gatatcacag acgaaaaggc tgttccactt accaaacaac tcatggatga ctacgagcgt
     9781 acccacgcgt ctactatcgc tgtcatgcca gtccctcatg acgaagtatc tgcttacggg
     9841 gttattgctc cgcaaggcga aggaaaagat ggtctttaca gtgttgaaac ctttgttgaa
     9901 aaaccagctc cagaggacgc tcctagcgac cttgctatta tcggacgcta cctcctcacg
     9961 cctgaaattt ttgagattct cgaaaagcaa gctccaggtg caggaaatga aattcagctg
    10021 acagatgcaa tcgacaccct caataaaaca caacgtgtat ttgctcgtga gttcaaaggg
    10081 gctcgttacg atgtcggaga caagtttggc ttcatgaaaa catccatcga ctacgccctc
    10141 aaacacccac aagtcaaaga tgatttgaag aattacctca tccaacttgg aaaagaattg
    10201 actgagaagg aataacaaaa tcatttatat aaagattagc cacacataaa ttaagtaaat
    10261 tctctacttg aatctaccta tttaataaaa actaatgaaa acgctatact tgtatttgtt
    10321 ttttcattaa aataagagta gaataaatta gtatagtaaa acaaaaaagc accgaatcgg
    10381 tgcgcacttt ttcaagttgt gtacggacaa agccttattt taactttgct atgttgtttc
    10441 gaatggttcc aaaataataa ataattttaa atttgactta actgttggag tagtcatggt
    10501 taaattaaat caaccgagcc gaacataagt tgtttaattt tgtggaagct attaataaaa
    10561 atataataag ggagaaagat aggtgtaatt ttaattttaa agtaattgcg gacactatca
    10621 aagtaaaaga ttatggagaa caaatttgta gaatttatcg aaaacaataa aaaagtaatc
    10681 atttcatcag ttgcagttgg tgttgtattg gtattagggt ttggatggta ttcatataac
    10741 caacaacaag cagaacaaca agcaaaaatt gtacaattag aaaaagatag caaatcagac
    10801 aaagaacaag ttgataaact atttgaatca tttgatgcat cttcagatga atctatttct
    10861 aaattaaaag aactatctga aacttcactt aaaaccgatg caggtaaaga ctatcttaat
    10921 aacaaagtca aagaatcatc taaagcaatt gtagattttc atttgcaaaa aggtttggct
    10981 tatgatgtta aagattcaga tgacaaattt aaagataaag caaccttaga aaataatgta
    11041 aaagaaatca ataaacaaat tgattttatc aagaaagttg atgaaacttt caaacaaaaa
    11101 aaattggatg aaactgtaaa atctcttaca gatattgcag acaaattcca aaaacaaatt
    11161 gatgttctga agaaagaaga agaacaaaaa gcatctgaca aagctaaaga agataagaag
    11221 aaagaagaat caacttcatc tcaatcttca aatagttcat ctcaagcatc aagcagttct
    11281 tttagttcat attctggtaa ttcagattat gctccagaac aaacatacac agctgataat
    11341 agccaatctt attcaggttc aactggtgga gacaatagta actataaagc accagctgct
    11401 acagacaacg gaggaaatga tggctatatt cttgggcacg taactggtgc agatggatcg
    11461 caaagagatt tttattttaa ccgttcaaac ggagatgttc gtgatacaag cggcaatcac
    11521 gtaggaaact ttggaggggg cattacagat tttagacaac gttaataact attttagggc
    11581 tgtgttgttt cgaatggttc caaaacacat taaaagctac tcatttttta agtagctttt
    11641 ttcttattca agtttacata ttagttgtca caaccccatt cccttgtaga aaagcaaaat
    11701 ggcgagtcct acgaacaaga ctaccgctcc taatctctgg ctggtattat acatccgttt
    11761 ttctcctcta actggaaaga taactgctag aaatgcgcca ccaactgcac caccgatatg
    11821 gcctgctagg ctgattcctg gaatcagaac acttccaata atgttaacca caaaaagtgt
    11881 cagataggat tgccctagct gttggatata aggattgcga gttgcatagc gaagaacaat
    11941 aatcgcggca aatagcccat aaagagaggt agaggcgcct gctgctaagg atttaggact
    12001 aaatacaaaa acaaagagat tgcccatcat tcctgataag agatagagaa aaaagaactg
    12061 cttagagccg aaaatctcct ctacctgcct tccaagataa taaagtgaaa gcatattaac
    12121 aatgaaatgt tcccacccaa tatgaacaaa aatggcagac aagagacgcc aaacctgctc
    12181 gggaaagagg cgaatagctg gcccatacat ggctccaaat cgaaataatg tatctgccct
    12241 gtcaaagttt ccgcctgcag tgaccaacat tagtaaaaat accaaggccg tcactaagag
    12301 gaagaaactc gtcacagggt aacgtctatc aaagatttcc ttcatcaatt aatacctcct
    12361 gaacaggaat atcatggttt tcaggtataa agtcctgaat ttgacaagga tatatcgtac
    12421 tcaaagtacg accagaaaaa tgttccaaat agcggtcata atagcctcca ccgtatccta
    12481 tccgatatcc tttcgtcgta aaagccagac caggaacatg aatcaaatca atctgagatg
    12541 catccaccac ttccacatct ccctgtggct ccagtaaggc aaaggcagtt tttaccaact
    12601 gttgcggatc atagaccaca aactccatgc gccccttggg ataagttttg ggtattaaaa
    12661 ccttcttgcc gtccttcagc gcctgctcaa tcagttcccg cgtttgaaac tcatgagaaa
    12721 aagagaggta ggttgcgatg accttggctt cttggtagaa gggatggtgt aaaagccgct
    12781 cggttaaagc ttggtctata gcctgttttt gctcttgaga tatagccttc atttcatgca
    12841 agacttgctt gcgtaattcc gatttcatag acaagccctc tattctgctg ccttcttttt
    12901 caggaaacta gacaccgcag ccaccccaat agctaagact tcttccttag gactcatttg
    12961 agggtgatga agagcgtagg gactatcgat acccagccaa aacatcacgc catcaacctt
    13021 tgaaaggaga taaccaaagt cctcgcctgt catagcaggt tcgatatcaa tcaactcgat
    13081 tccgtctttt tcgtcaaaga agtccatcag ttcacgcgcc aaggctggat tgttctcaac
    13141 aggtaggtat ccaccttgtt tgagttccac ttcgacttcc atatcaaagg cagctgcaac
    13201 cccttctgca actgttttta ccctcttttg caccaagaga ctcatgtcct gtgtcaaggc
    13261 acgaatagtt ccatgtaaaa aagctgtttc tgtgatgaca ttgttggtgg ttccagcttg
    13321 aaaaacgccg aaggtcacca ctgctccctc gattgggttg acattgcggc taacaactga
    13381 ctgcacttgg gtcacaaagt aactagccgc taccaaggcg tcattggctt catgaggaaa
    13441 agctgcgtgg ccacctttgc ctttgaaacg gatcttcacc tcgcaagttc ctacaaagag
    13501 tgtatgagta ttagtcgcaa tctggccgac tttcaaatct ggacgaacat ggagaccata
    13561 gaattggttt ggcaaccaat ctccaaaagc accgtcctca tacatgagca taccaccagc
    13621 ttcattttct tcagcaggct gaaatagaaa gagcagatta ttcttgggtt gctcctcaag
    13681 ggcgcgctca agacagccta aggcaatggt catatgaaaa tcatgaccac aggcatgcat
    13741 gcgaccttgg tgttgagaag caaaaggtag acctgtttgt tcgacgatag gcaggccatc
    13801 aatatctgtc cgccaaccaa tggttcgctc cggctgactt ccctgcaggt agaccaaaat
    13861 ccctgtccgc caagtacgaa tttgaacaaa atccttgccc gtagtcaatt tctcaatcac
    13921 atccagcaaa taagcctgag tcttgaactc ctccaagcca atctctggta tctggtgtaa
    13981 atctcgtcta gtctgaatca aatctaacat ctatctgtcc tccgatatag cagaaagagg
    14041 ctggaaaaag ggttccgcct cttttttact tttacaatta caaggtacga agcgcatcct
    14101 ctagcgctgt tttttgttgg gtttgggcat caatttcttt gatgatacga gctggaacac
    14161 ctgctactac cacgttttct gggacatctt gggtaacgat agctcctgca gcgacaactg
    14221 aaccactacc gatttggact ccttcgataa ccactgcatt agcaccgata agaacattgt
    14281 ctccgacacg gactggttca gcactagctg gctcaatcac acctgccaaa actgcacctg
    14341 caccaacgtg gctatttttt ccaacgatgg cacggccacc aaggatggca cccatgtcaa
    14401 tcatggttcc agcaccgatt tcagcaccga tattgataac agatcccatc atgataacag
    14461 cattgtcacc aatttccacc tggtcacgga taatagcacc tggctcgata cgagcgttga
    14521 tagcacgctt atctagcaaa ggaactgcag aattacgagc atcttgctcg acaacataat
    14581 cttgattttc taccaaacct tcaagaagcg gagccacgtc cttccagtct ccgaatagga
    14641 catttcctag tttgacaaca gagctaggca cagcagttgc gagttgcccc tcaaaggtta
    14701 ctttgacact ggttttcttt tcagcattgg cgataaattg gataatttct tgagcgttca
    14761 tttttgtagc agtcataggt gcctcctggt tcgttataat gatacctatt ctaccaaaaa
    14821 aggcctcaaa tttgaaacct ttttgtctgt ttttaggtat gattttttag ggatgtgaga
    14881 taaaacgtgc tgtcggtaaa agcaagcccc taccgataca acctaaaaac actcttcaca
    14941 actatctccc cgtgttttat tgactattct agtatagcac acttttagaa ttaagaaaag
    15001 actttttatc tactttcttt cgcttcttct atagacaaaa atatcatggg taaaataatc
    15061 aaggctatag ctagaaggag ggaccaatcc actactaatc ctaagaacaa aacactcaag
    15121 agagcagaag agagaggttc actggcactg ataacggcaa ccaccaaagg agaaaccaag
    15181 gacacagcct tcatggaaat gaaaaaagca aaagccgttc caaagaaagc gataatgagg
    15241 caaatcaaga tactccaaat atcaagagta aaggaaagct gataaaccgg cgagaggaca
    15301 ttgctaaaca aacctgccaa aatcatcccc cacccaaccg taggaacaaa accataacgc
    15361 ttagcaaaag gttggggcaa gataacatta aacataacac ccatggcact cagcaaacct
    15421 gttataagag ctagcggcgt catggataac tgagagagat ctccctttgt cgccatcaag
    15481 caaacaccca gcatggcaac caaaacatag aaaacagcgc tttttgacgc tcgtttttga
    15541 taaaccaagc gattgtaaaa gaggataaag acagggctaa taaactgtaa aatagttgct
    15601 gtcgtagcat ttgagtattc tacacagaga tagaaaaaat actggactga aaaaatcccc
    15661 aaaatagcat aggctaaaaa gggcaggtaa tttttcttgt ctcgccaaat atctagcact
    15721 tgcgatttta attgtattgc agaccaaatg agtacaatac tccctgccag tgtcaaacgc
    15781 atagaggtaa tccagcccga agacacctga taatgagtaa agaagtactc tcctaaaatt
    15841 ccacagattc cccatattaa gccggatagg agcgaataaa tttttccgtt aacaatcttt
    15901 ttctgatact gattcatacc cttattgtaa cacgaaagga aaaaagtggc aatccattga
    15961 ttggccactt catttagaga attatcgtct cgcccttgaa gaagaaggtc gtgtagtact
    16021 tgagttactg ctatcgctag aactactact tgaactgctg gagctggatg gagttggtag
    16081 actccccaca atactagacc aagcattctg ataatccgca tcacttccgc caatagcaaa
    16141 gcgataactt gtcgctggcg ctcctgactt attagcccaa tagctggtaa cagtcgaacc
    16201 tgtgacctct acctcttttc cttcaacaga aaccttccct ggtttttgac ctgttgattt
    16261 caagacttcc gatttcacta cactaggatc taaagcaaag cgctcgttcc cccaaatgct
    16321 tggggaagct tgctgaatcg catttactag atgagccatg taattagagt tattagaata
    16381 acctgctcta cgtgacaatg aatgattatc atcatgccca atccagccac ctagggttaa
    16441 tctaggtgtc gaaagcatga gccacatatt ttcgtcttgg ttggttgtac cagtcttccc
    16501 aatccaatct gcattagcca gagtaggatt taaagaagtc aggttagact tgaaggttgt
    16561 tgtcacacga gaggatagaa cttctcgtag caatccctgc ataatcgtcg cagtagcttt
    16621 tgaatagact tgaaccggtt tatcctgata ctcatacacc actctaccat ctgctgcttc
    16681 aatctttgaa atcacatgct tctgatgata aactccatta ttagctaagg tctgatagcc
    16741 attggtatgc tgggcaactg tgacttcaat accaccaccc attggcaagc tctcaatacc
    16801 gtactcagga atctcgtaac ccatcttttc catataaccc ttgacatcaa caccattttc
    16861 acggagcaga ctataggtcc agtaagcagg gatattccat gagtagttca gagcttctcc
    16921 caaggtcatc attcctgttc ccttgctatt agcatacata atcggattgc cattagcaaa
    16981 gtttgttgga tagttagata gaatcgtttc acttcccatc aagccctggt caatagcaat
    17041 accgtaggcc agcaagggct tggtagtaga agctggcgaa cgtttggtat caaaggcatg
    17101 attattttga ttttcttgat aattacgacc acctacaaag cctagaatag cacctgtttg
    17161 gttgtccatc aagacattcc ctacttctac acgacctgtt ccatcgtcta aaagatagcc
    17221 ataatcagca accgcacttt gcatggcaga atgaattttc tgatctatgg tagtagtaat
    17281 cttataacca ccattttcaa tttccttggc tgccaaatct cgataaaact tctgagttgc
    17341 ctcatttttc aactccttag cggagacatt gtctctctga gctagatagt catacatacg
    17401 ttcttgagct tctgccaaag ttgtaaagta taaatagtct cgtgaaattc ctgtaaccgt
    17461 gcccgatggt aaaaagtcct gtttaaggtc ataatccttg tactgagaat actcgtcttt
    17521 gcttaatgca cctgtacgat acatactgta aagaactgcc ttagcccgtc ttaagccaat
    17581 ttctaggtct tcatcactct tcaactcccc agtattttca taaggagagt aagtaatggg
    17641 actctgtgga agtcctgcta aaaatgctgc ttgaggaaca gtcaactgac tggcatctac
    17701 accgaaaatt ccctcagctg cttgccgagc ccctgcaata ttctgtccct tattatttcg
    17761 gccaaaggga gccacattga gataggtcgt taaaatctca tctttattca tggcgcgttc
    17821 caaggcaaga gcatccacaa tctctgccgc cttacgagcc aaggtcggcg catccccaac
    17881 cacctgctgt ttaattagtt gctgggtcaa ggttgaaccc ccactagagg aacccaaacc
    17941 tacaaatttc cccaaggtcg cacgaatcac cgccttgggt actacaccct tatgttcttt
    18001 aaagtgttca tcttctgtcg caatgatagc cttcttcaga ttttccgaaa tttgctcaga
    18061 tgagatagaa gtgcgcaaca aatcactctc tatggaagca atcaccgtcc cgtccgaata
    18121 ggtaatctct gaaatagaag agatgtcctt gacctgattc accaattctt ctgtctgagg
    18181 cacccgaacc ttgtcaaata aggccactcc gtaccccaaa gcaatcccag ctcccaacat
    18241 tcctcctaga aaaccgagta caaagagtaa gttaaataag gcttttatac tcagtaaaat
    18301 agctgggaaa atggctgact tatctaaggt tttagatttt ttggtacttg aacctttctt
    18361 gccaggtcta gctgattttt tatttttttg tttttgctgg aaaaattcca gcatttttcg
    18421 ttttaattca tttaattgat tttgcatgga tttcctcact ttatctatta taccacaaaa
    18481 gggaaatttt caataaaata gccactttct tccctattct gctaggctat tgcccaagtt
    18541 tgtgatacaa taggtagaaa caataatttt aaaaaggaga aaaaacacat gcacattttt
    18601 gatgagctaa aagagcgtgg tttgatattt caaacgactg atgaagaagc tttgcgtaaa
    18661 gccctagaag aaggtcaagt ttcttattat actggctacg atccaactgc tgacagcctt
    18721 cacctaggcc accttgtcgc aatcttgaca agtcgtcgct tgcaactagc aggtcacaaa
    18781 ccttatgcgc tcgttggcgg tgctacaggt ctcatcggag atccgtcctt caaagatgct
    18841 gaacgtagtc tccaaacaaa agacacagta gatggctggg tcaagtctat ccaaggacaa
    18901 ctttctcgtt ttcttgactt tgaaaatggc gaaaacaagg ctgtcatggt caacaactac
    18961 gactggtttg gcagcatcag cttcattgac ttcctccgtg atattggaaa atacttcacg
    19021 gtcaactaca tgatgagtaa ggaatctgta aaaaaacgaa tcgaaacagg aatttcttac
    19081 actgagttcg cttaccaaat catgcaaggg tacgacttct tcgtccttaa ccaagaccat
    19141 aatgtcactc ttcaaatcgg tggttctgac cagtggggaa atatgacagc tggtaccgaa
    19201 ttgcttcgtc gtaaagcgga caagactggt cacgttatca ctgttccact aatcacagat
    19261 gcaactggta agaaatttgg taaatcagaa ggaaatgccg tctggctcaa tcccgaaaag
    19321 acttctccat acgaaatgta ccaattctgg atgaacgtga tggacgctga cgctgttcgc
    19381 ttcttgaaaa tctttacttt cttgtcactt gatgagattg aagatattcg taaacaattt
    19441 gaagcagcgc cacacgaacg cttggctcaa aaagtcttgg ctcgtgaagt tgttacactt
    19501 gttcacggag aagaagccta caaagaagca cttaacatca ctgagcaact ctttgcagga
    19561 aacatcaaaa acctttctgt caaagagctc aaacaaggac ttcgtggtgt gccaaactac
    19621 caagtacagg cagacgaaaa caacaatatc gtggaactgc tcgtctcatc tggtatagtt
    19681 aactcaaaac gccaagcccg tgaagacgtc caaaacggag ccatctacgt aaacggcgac
    19741 cgcatccaag agcttgacta tgtcttgagt gacgctgata agttagagaa tgaactgact
    19801 gttatccgtc gtgggaagaa aaaatacttt gtattgactt actaaactat tcaacattta
    19861 tctataaaca aaggagttag cctcgagaaa ggtaactcct ttttgctgtt aataactctc
    19921 atctatctat ttttaataga caggctacgc aggacaatgc gcaaggttgt tagattatgt
    19981 aagatagaga gatttgaagg actgagccaa ttaaataagc cgaagccaat caaactacta
    20041 tttacgacaa cggtatcttg aatatttttc ttgatgagtg tttgcaaaga tgatgataac
    20101 gaatccaact cttggaagaa atccaaacga ttatctaaca ataagatatc actcatctgc
    20161 ttagaaatat ctgcactctc attcatcacc acaccgatat ctgatagagt taaagccgct
    20221 gagtcattca atccatctcc aaccatcaaa atagtgtgac ctgctttctg cagtttctct
    20281 actaactcaa atttcccatc aggtttcaag tctgtataga cctgatcaaa gggcaaatct
    20341 ttgactaatt cctctgtcct agtcaaggtg tctcctgttg ccagaatcaa ttttttcccc
    20401 tgtgccttaa gtttatccaa ggctgttttt gcttcttttc tcaaaggagt atgaatgcag
    20461 aacattccaa tcaattcatt ttgataagcc aagaataaga gattgtagtg actcttgtac
    20521 tcttcaatta aagcattttg ttctgaactg atatgaatct gctcatcctg catcaagaca
    20581 taattcccaa taagaactgg ttggccatct atatgagatt tgatcccctt gcttgcgata
    20641 tattggagtt tcccatgcat ttcctcatgt tcaattccct ctatctcagc ttgcttgacg
    20701 atggcattag caataggatg ataaatgtgt tcctcaagac aggcactgat tctgagaata
    20761 tcttcctcac tatagtctcc aaaaggtaac accttttcaa ctataggata actagttgtg
    20821 attgttcctg tcttatcaaa caagaaagta tcaacttcca gatatttctc cagaacatct
    20881 ccatccttaa tcaccatttc acggttcaac ccttccttga taactgtcaa ataagctaca
    20941 ggagtagaga ttttcaaagc gcaggagaaa tcgaccaata ggaaagaaat agccttagaa
    21001 aaagaacctg tcaataggta agtcagccca gaccccaaga aattatattt gacgacttta
    21061 tccgccatct tgatgaaata gcgttgtttc gttttcttgt tttcttcaga tttcttcatc
    21121 aactcaatca gctgtaaaat acggctgttc atctgattat ctgttacacg aatgcgtaac
    21181 tctccagttt ctaatactgt atttgcacaa accaaatcag actctctttt ttcaactgga
    21241 aaactctctc ctgtcaagga actttcgttg accataccta aacctgaaac tacttgtcca
    21301 tcaaacagaa tttcatttcc ttgagataag atcaagacat ctcctatttg aacatcggaa
    21361 ctcttgatac taacaaccgt atcgccctgt actaggaata catcgctctc ttttgcaaga
    21421 agactctgtt ctaaatctgt tgcagttttt ttcaaggacc actgatctaa atgattcccc
    21481 aaatcaagca taaacatgat attgctagct gtcttggatt ggttcataaa caaggacaat
    21541 aaaatagccg aacagtccaa gacttccatc gttagttcct tacgcgctag tgtttgatag
    21601 gcttctctaa tataacccaa agcctgataa caagtccata tatagcgaat aggatacggc
    21661 acaaaactac gaaaaagtac acgcttaacc gctgcacctg aaacaataga ataagcactc
    21721 tcttctctac gaatgggaag agtcatcaac tcagaaactt tccctttatc aattcttttt
    21781 aaaaaggctt ctgcattatc taatacagaa aagccttctt ttatgcgtag agtaaagtgc
    21841 tgttgatcca tgtaaaactg gatagactca atcccctttt catctctcgc caaggaacga
    21901 agatagtctt gaatatccaa ggtaagtgaa aaagaagatg atagtcggat atgttggtat
    21961 cctctatgta gcactttaaa agacatatta ttcacctata aggctatcta attgctcttc
    22021 ttttttctct tgctcgtaca aatatttggc atcttgcaag acatcgtctc catgttgctt
    22081 cacaacagaa acagatgcat ctagctcgtc tttcaacttg taagccttag ccaaagcttt
    22141 agaataacct tttttagctt ccttacttgc taagattttc aaaccaaggg taccaaatgc
    22201 gacaccaccc aaaaataatg aagatttttt cgcaactttt gcaacggtta atacttcttt
    22261 taacatactt atttcctcct tatcattatt atatagcaat ttagatataa aagcaatttc
    22321 attctataaa ttggagaatt agttttattt ctactgaatc tcccatctac ttattcctaa
    22381 agttgctttc atttgcctct tttgatacac ttaaactatg aatacaaatc tcaagcccaa
    22441 acttcagcgt tttgcttctg cgactgcctt tgcctgtcct atctgtcaag aaaatctgac
    22501 tctgttagag actaatttca agtgctgcaa ccgtcattct tttgacttgg cgaaatttgg
    22561 ctatgtcaat ctagcacctc aaatcaagca atctgctaac tatgacaagg aaaattttca
    22621 aaaccgtcaa caaatcctag aagccggctt ttaccaagct atcttagatg ctgtatctga
    22681 cttgcttgca agctcaaaaa ctaccacaac aattttggat atcggttgtg gtgaaggatt
    22741 ctattctcgc aaactacaag aaagtcactc tgaaaaaact ttctatgcct ttgacatctc
    22801 caaagattca gtccaaatcg ctgctaaaag tgaacccaac tgggcagtca attggttcgt
    22861 tggcgacttg gcacgacttc ctataaaaga cgctaacatg gatattctgc ttgatatctt
    22921 ctcacctgcc aactatggag aatttcgtcg cgttttatcc aaagacggta tcttgataaa
    22981 ggttatccca actgaaaatc acctcaaaga aatccgtcaa agagtacagg accagctgac
    23041 aaacaaggag tattctaacc aagatatcaa ggagcatttc caggaacact ttaccatcct
    23101 atctagtcaa actgcctctc tgactaagac tatcacagca gaacaactcc aagccctact
    23161 cagtatgact cctctcctct ttcacgttga ccagagcaag attgactgga gccaactgac
    23221 agagattacc atcgaagcag agattttggt tgggaaagca ttctaaacta gacttcccaa
    23281 aggtataaaa cttaccgaaa atcttcaata ttataaaaac gcataagaac aggtacacaa
    23341 accttaatct tatgcgtttt gttatagttt ccatacacat taaggggaaa tagttgaaat
    23401 cagttctctt aataaccatt gaataccata tactacattt accccaaata tgatataggc
    23461 cgtataaatc aagtatttcg atttttcccg cctcaaagaa tagatcttat acaaaataaa
    23521 taaatttaaa ataataaata atagagacaa aatcttcctc caaaatcaat attaaaagta
    23581 gccagtcaat catagttcta atctttattt tcgattcgaa attacaaact tatcaatgaa
    23641 caataagtga tataaggcca gtaccagacc ccaaacgcta ccacgaaaag agaattcttg
    23701 atgattgaga gtaaacaaat catggttacc aatatagagg caggtcaaaa taacaaataa
    23761 aatccaaaat aaatccgtcc atttatattt tgaaaaatat ttttttaaca taatagcata
    23821 tttttttgac tataataaca gtatatgata aaatgtaagc agatacaaat aaaaaggaga
    23881 aaagctcatg aacaaattaa tgaaatttat ttcggttttt ttgacgtcaa ttgtgttaat
    23941 tgtatcagcg attccaagtg tttcagctgt atacgcttct gaacaagtat cacaaattga
    24001 aacaaatatg gaacttcaac ctgtcacttc tctaacagaa gaacaaatca atacacttgc
    24061 aaacgaaatc caatcttttc atccagacgt ctcacaacaa tggatcaaag aagtaattaa
    24121 ccgacaatta caaggcgatt atacaatccc acctacatac tctccattta gagcagcttg
    24181 gcaaggtatt acagttaatc aaatgggtgc tctattagat actgcaatag ctttagcatt
    24241 aggaggaact actgcaggcc ttgcaaatct aattaaagta aaaggaaaac atgcagcaaa
    24301 aagtgctatt cgttcagcaa tttctagata tctaggtagt tggtttgtaa atgatgttgc
    24361 tttagaattc gctatgaatt tattatcacc ggggacttat ttagcacaat tatgggataa
    24421 aaatgatgcc attcctaaca acggaaggat taacttttaa tcatgagata tacaataaaa
    24481 ttaattgggt ataacgtatt ttcgttgttt atattcttta tcttatcaat gttgtttaaa
    24541 gttcccttta ggtggtggat cagcattgca atgacgactt cgtcgtacat tgtatataat
    24601 tacttaaaga aaaagagaga aaaggaatga tcttatacca gatcattcct tttctgcttt
    24661 ctgtaaatcc ctcggagtgt gtttggcgct ttgatacgaa gtgtcaaagc tgtataaacg
    24721 ttactatttc caaaaaagta acagaaaatt cctgctttgt aggactgctt tgggtgagta
    24781 atagacatgt cgactcaccc tatctcctga tggcgaaaag aatttagcaa tggtgcaagt
    24841 tgttctgaac tcgagaaaaa acatgccgaa atcgaagaaa agcgtgcaga acttgaagcg
    24901 aagaagcaag aaatgttgaa tcgcttggat aaatagaatt tagaaaacag aaaaactaaa
    24961 aagaatgtag ggtttatttc cctacattct taaaataact tagtacataa atgacaatgc
    25021 tgccactgcc gtcaatattg caaaaactat tttccaaatt tttttatttt ttccaaaaat
    25081 cttatcaggt aacaagctta ttacaagaaa ggtaataaac aacaccaatt taagtgtgta
    25141 tatcataaaa acaccttctt tcctacaatt atattataat actttatgta agcgaataca
    25201 agagatgtga ggtaaccaac tacgaaaaaa tataaggctg aagacagtaa aaaccagcat
    25261 ttaaagcctt cactgtatct aggatttccc tatttttaga caagattgac ccaaatccac
    25321 agcatttaaa aaagcgaatt tcaatcgaaa ctcgcttttt tacaaaatgt attagtataa
    25381 atttgtatct tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc
    25441 tcaaagcacc gctttgaggt tgcagataaa gctgacgtgg tttgaagaga ttttcgaaga
    25501 gtattagttc aagtgccaga tgtcttcatt atactgagcg attgtacggt cagatgagaa
    25561 gaatcctgct ttagaaatgt taacgatgac tttatccaac catgcgtcac ggtcttcgta
    25621 gtcagcaagc atttgctctt tgactttgat gtagtcttcc aagtcaagaa gagtcatgaa
    25681 ccagtctttg ttgatcaatt cattgtaaag acgttccaag cgctctttgt ttccagctgc
    25741 aagaactgca tcactaacga tgaagtcaac caatggtttg atagcttcac gagcgtagaa
    25801 ttcgcttgat ttgtaagctg cttttgcgta aaggtcgata acagtttctg aatcttcacc
    25861 gaagatgtag atgttttctt ctccaaccaa ctcagcgatt tccacgttag caccgtccat
    25921 agtaccaagt gtcaaagctc cgttcaacat gaatttcatg ttaccagtac ctgaagcttc
    25981 tttagaagca agtgaaattt gttctgagat atcacatgct gggataagga aacttgctgc
    26041 agtaacgttg tagttttcaa ccataactac ttgcaagtgt ggagctactg ctggatcgtt
    26101 agcaataact tctgacatgc aaaggattaa atggataatg tcttgagcga ttgtgtaggc
    26161 tggagctgct ttaccaccaa agaagattgt gattggacga gcagggatgt taccagcttt
    26221 gatgtcaagg tatttgtgga tcacgtacaa agcgttcatt tgttggcgtt tgtactcgtg
    26281 aagacgtttg atttggatat caaagataga atttgaattg atttccacac cttggtgttc
    26341 tttcaagtga cgagccaatt tacgtttgtt gtgagccttg atgctttcca atttttcttt
    26401 gacagctgct ttgtcttcat aagacaaaag tttttcaagc tcatctgctt catggtgcca
    26461 accatctcca agaatctcat ctaagtagtg agacaatctt gggttagcat gcataagcca
    26521 acgacggaaa gtgataccgt ttgttttgtt gttgaacttt tctgggtaaa ggtcgtagaa
    26581 ggctttcaac tcagaatttt tcaagatttc agtatggagt gctgcaaccc cgttaacact
    26641 gtatccgtag tggatatcca tgtgagccat gtgaacacgt ccgctctcat cgatgatttg
    26701 aacagctgga tctttgtact ctgccttcac acgacggtcc aattcttcga tgattggtac
    26761 caagtgagga accacttctt gcaagaattc aagaggccat ttttcaagcg cttcagcaag
    26821 gattgtgtgg ttagtgtagg cagtcatgct acgaacaatt gagattgctt cgtcaagctc
    26881 gataccacgt gcagttaaaa gacgaatcaa ttcaggaatc accattgatg ggtgagtatc
    26941 gttgatttgg acaactgcgt agtcagcaag gtcatgcaag ttgcttcctt tttcgattgc
    27001 ttcgtcgatg atcaattgcg caccgtttga aaccatgaag tattgttgga agatacggag
    27061 caattcacct tgacggtcac tatcatctgg gtaaaggaag agagtcaagt tgcgagcgat
    27121 atctgtcttg tcaaagttga taccatcttt aataatagaa gaatcaactg aatccaagtc
    27181 aaacaaacgc aagcggtttt tagtcgctgt ttcataacca gtaacatcaa tatcgtaaag
    27241 agttgatgtc aaagtaaagt ctgcaaatgg tacttggtag ctacggcttg agcaaaccaa
    27301 ccagttttgc tctgtcaacc atgcatttgg aattgtttct tgttggttgt ttttaagaac
    27361 ttgttggaaa agaccaaagt ggtagttaag accaacaccg tcaccattca aaccaagagt
    27421 agcaattgag tcgataaagc aggcagccaa acgtcccaaa ccaccattac caagagatgg
    27481 ttccaattca acttcttcaa cttcgatcaa gtctttacct gcagctgcaa gttctttttt
    27541 aacatcgtcg taaagaccaa ggttaatcaa gttgtttgac aagagtttac caatcaagaa
    27601 ctcagctgag atgtagtaaa cttttttctt accagtgttg actggttttt ggctgcttgc
    27661 aagcttgctg tagttaagaa gagcaaggta aagctcttca ttgctacatt ctgcaatggt
    27721 tttattgtaa cgattttgta caaattcttg tagtgataac atgtttagtt gtctcctgat
    27781 tattgtctta tttctttaaa tctaccaaat tttcattaat tcggcgataa attgttgtca
    27841 agtcaagcaa accttcctcg acagctggtg tcaattgatc ttcagtcata cgccaagacc
    27901 agtttccacc aagggtagat gggaagttca tacgagctgc ctcatccaat tctagtaaat
    27961 cttgcatagt cgcaattgcc ataaagctaa ctgatgaaaa tactgtacga agcatagcgt
    28021 gtaccactgt ttcgtattct ttacggttcg tgtaacgagc catgtactca cgagtcgcat
    28081 catcaatctc attacggtac caaccaagaa ccgtattgtt atcgtgtgtt cctgtgtaca
    28141 taactgagtt agcaggtgcc aagtgtgggc tatcaatgct ttcgtcttct gggttgaagg
    28201 caaattgaag aatcttcatt cctgggaagc cagtacgttc acgcaattcg atcacttcat
    28261 ctgtcatgaa gccaaggtct tctgcgatga tgtttagctc accaagttct tccttaacgg
    28321 ctgcaaaaag cttgtagcct ggacctttca cccactcacc aggtgctgct gtatcggaac
    28381 cagcagggat ttcccaataa gattcgaagc cacggaagtg gtcgatacga acgatatcgt
    28441 agattttgaa gctttcacgc aagcgttcaa tccaccattt gtagccgtct ttgtccattg
    28501 cttcccagtc atagattggg ttaccccaaa gctgaccagt tacagaaaac tcatctggtg
    28561 gacatcctgc gatacaagta gccttaccat tgacatctgt tttgaagaga tgtggatttg
    28621 cccacatatc acttgaatct tccgctacgt agattggcat gtccccaacg atttcgatgt
    28681 ggttgtcgtt agcgtaagct ttcaatttca accattgttg gaagaagaag tattgagtca
    28741 cacggtggta aaccaacttg tctgccaatt gctcacgata gctttcaagt gctgaagctt
    28801 tacgagcacg agcatctgca tctggccatt cagtccaagc aagattgtca aaatgctctt
    28861 tgatagccat atactcagca aagagctcaa gccatgattg gttgtcttga gcaaatttct
    28921 caaaatcttt aacatatccg acttcaaaga aacgcttcac cgctttttct aaaagaggac
    28981 gacgtgcata gtagatttta gcatagtcaa cttcagacgc atcgctacca aagtcaactc
    29041 cttcaaggtc acttgcttcc aacaaacctt gctccaccaa gatatctaaa tcgataaaat
    29101 gagtgtttcc tgcgaaggct gagaaagatt ggtaaggaga atccccgtaa ctagttgctc
    29161 ctaatggaag gatttgccag taacgttgtt ttgtacggac caagaaatca acgaagtcgt
    29221 aagcactttg accaaatgat ccgattccgt aagctcctgg aagagaagag atgtgcatca
    29281 acacaccact ttgacgtttt ttcataatag cacctcgtgt gttaaaataa tggaacgttg
    29341 cgtatttttc agacgcaaac gtttgcgtta cttataagta tactcctttt caagcataat
    29401 tgcaagcgtt tttaaaaaac ttttttgatt atttttaagg agactaactc attttagcaa
    29461 agataactta aaactatcta atcctaaggt ttgactctca cgagacagta tacaaagtac
    29521 aaaacctcct tagggagctt gaatttatat gcaacaaagc acaaacgtct atagaaaata
    29581 gatatagatt agaaataggg aggtagcccc tcctgatttc cctctttaga cagattccat
    29641 atatttttat taaaaatact gtattcttat ctatttcata cttttcttct attaaaatgc
    29701 aaaattatgc tatcaaatca agcttaaaaa ttttttaaaa tttttacaaa aaatacttgc
    29761 aaccgttttc tatttatgct atactaagct cataaaggaa aacgtttgcg tttccttatc
    29821 aataaaactt gctattcttt gggaggaata cactatgtca tctaaattta tgaagagcac
    29881 tgcggtgctt ggaactgtta cacttgctag cttgctcttg gtagcttgcg gaagcaaaac
    29941 tgctgataag cctgctgatt ctggttcatc tgaagtcaaa gaactcactg tatatgtaga
    30001 cgagggatat aagagctata ttgaagaggt tgctaaagct tatgaaaaag aagctggagt
    30061 aaaaatcact cttaaaactg gtgatgctct aggaggtctt gataaacttt ctcttgacaa
    30121 ccaatctggt aatgtccctg atgttatgat ggctccatac gaccgtgtag gtagccttgg
    30181 ttctgacgga caactttcag aagtgaaatt gagcgatggt gctaaaacag acgacacaac
    30241 taaatctctt gtaacagctg ctaatggtaa agtttacggt gctcctgccg ttatcgagtc
    30301 acttgttatg tactacaaca aagacttggt gaaagatgct ccaaaaacat ttgctgactt
    30361 ggaaaacctt gctaaagata gcaaatacgc attcgctggt gaagatggta aaactactgc
    30421 cttcctagct gactggacaa acttctacta tacatatgga cttcttgccg gtaacggtgc
    30481 ttacgtcttt ggccaaaacg gtaaagacgc taaagacatc ggtcttgcaa acgacggttc
    30541 tatcgcaggt atcaactacg ctaaatcttg gtacgaaaaa tggcctaaag gtatgcaaga
    30601 tacagaaggt gctggaaact taatccaaac tcaattccaa gaaggtaaaa cagctgctat
    30661 catcgacgga ccttggaaag ctcaagcctt taaagatgct aaagtaaact acggagttgc
    30721 aactatccca actcttccaa atggaaaaga atatgctgca ttcggtggtg gtaaagcttg
    30781 ggtcattcct caagccgtta agaaccttga agcttctcaa aaatttgtag acttccttgt
    30841 tgcaactgaa caacaaaaag tattatatga taagactaac gaaatcccag ctaatactga
    30901 ggctcgttca tacgctgaag gtaaaaacga tgagttgaca acagctgtta tcaaacagtt
    30961 caagaacact caaccactgc caaacatctc tcaaatgtct gcagtttggg atccagcgaa
    31021 aaatatgctc tttgatgctg taagtggtca aaaagatgct aaaacagctg ctaacgatgc
    31081 tgtaacattg atcaaagaaa caatcaaaca aaaatttggt gaataaaaaa tttgttcaag
    31141 gggggtggaa atcaaatccc cctttgaatt tatcaataga gacacaaata atttagcttt
    31201 cttataaaaa agtagtatcc tatgaaagga gttaatatgg aaaagcaaca acctagtaaa
    31261 gcagccctgc tgtctatcat tcctgggtta ggacagattt acaataaaca aaaagccaaa
    31321 ggttttatct tccttggtgt aaccatcgta tttgtccttt acttcctagc acttgcaacc
    31381 cctgaattga gcaacctcat cactcttggt gacaaaccag gtcgtgataa ttccctcttt
    31441 atgctgattc gtggtgcctt ccatctaatc tttgtaatcg tttatgtact cttttatttc
    31501 tcaaatatca aagatgcaca tacgattgca aaacgcatta acaatggaat tccagttcca
    31561 cgcacactca aagacatgat caaagggatt tatgaaaatg gcttccctta cctcttgatc
    31621 attccatctt atgttgccat gaccttcgcg attatcttcc cagttatcgt aaccttgatg
    31681 atcgccttta ccaactacga cttccaacac ttgccaccaa acaagttgtt ggactgggtt
    31741 ggtttgacca actttacaaa catttggagc ttgagtacct tccgttctgc ctttggttct
    31801 gttctttctt ggactatcat ttgggctttg gcagcttcta ctttacaaat cgtaattggt
    31861 atcttcacag ctatcattgc caaccaacca tttatcaaag gaaaacgtat ctttggtgtt
    31921 attttccttc ttccttgggc tgtcccagcc ttcatcacta tcttgacatt ctcaaacatg
    31981 tttaacgata gtgtcggtgc tatcaacact caagtattgc caatcttggc taaattcctt
    32041 cctttccttg atggagctct tattccttgg aaaacagacc caacttggac taagattgcc
    32101 ttgattatga tgcaaggttg gctcggattc ccatacatct acgttttgac tttgggtatc
    32161 ttgcaatcta ttcctaacga cctttacgaa gcagcttata ttgacggtgc caacgcttgg
    32221 caaaaattcc gcaacatcac tttcccaatg attttggctg ttgcggcacc tactttgatt
    32281 agccaataca ccttcaactt taacaacttc tctatcatgt acctcttcaa tggtggagga
    32341 cctggtagtg tcggaggtgg agctggttca accgatatct tgatctcatg gatctaccgt
    32401 ttgacaacag gtacatctcc tcaatactca atggcggcag ctgttacctt gattatctct
    32461 atcattgtca tctcaatctc tatgatcgca ttcaagaaac tacacgcatt tgatatggag
    32521 gacgtctaag atgaataact caattaaact caaacgtaga ctgactcaaa gccttactta
    32581 cctttacctg attggtctat caattgtaat tatctatcca ctgttgatta ccattatgtc
    32641 agcctttaaa gcaggtaacg tctcagcctt taaactagat actaatatcg acctcaattt
    32701 tgataacttt aaaggcctct tcactgaaac cttgtacggt acttggtacc tcaacacttt
    32761 gattatcgcc ttaattacca tggctgttca aacaagtatc atcgtacttg ctggttatgc
    32821 ttacagccgt tacaacttct tggctcgtaa acaaagtttg gtcttcttct tgatcatcca
    32881 aatggtgcca actatggccg ctttgacagc cttcttcgtt atggcgctta tgttgaacgc
    32941 ccttaaccac aactggttcc tcatcttcct ctacgttggt ggtggtatcc cgatgaatgc
    33001 ttggctcatg aaaggctact tcgatacagt gccaatgtct ttagacgaat ctgcaaaact
    33061 agacggtgca ggacacttcc gccgcttctg gcaaattgtt ctaccacttg ttcgcccaat
    33121 ggttgccgta caagctctct gggccttcat gggacctttc ggggactaca tcctctctag
    33181 tttcttgctt cgtgagaaag aatactttac tgttgccgta ggtctccaaa ccttcgttaa
    33241 caatgcgaaa aacttgaaga ttgcctactt ctcagcaggt gctatcctca tcgcccttcc
    33301 aatctgtatt ctcttcttct tcctacaaaa gaactttgtt tcaggactta caagtggtgg
    33361 cgacaaggga taatttatcc ccgccaccct ttttcatttt atactcttcg aaaatctctt
    33421 caaaccacgt cagctttatc tccaacctca aagttgtgct ttgagcaacc tgtggctagt
    33481 ttgcactttg attttcattg attattagca attgtcactg taaataatat ccttgtagca
    33541 agcaattttt ctcctagact tgaaataaag cgcatttctc tatataataa tactcatata
    33601 gaaaacacct tttagaaaga tacctatgct tccatatcca ttttcctatt tttcaagtat
    33661 ttgggggttt cgtaagcccc tgtccaaacg tttcgagctc aactggtttc aacttctctt
    33721 taccagtatc ttccttatca gcttgtctat ggtacccatt gctatccaaa acagctccca
    33781 ggagacctat ccgctagaaa cttttatcga taatgtctat gaacctctga caaatgaggt
    33841 tgtccaggat ctctctgaac atgctacaat tgtcgatggc acattaactt atactggaac
    33901 agctagtcaa accccttctg ttgtgattgg tccaagtcaa atcaaggaat tacctaagga
    33961 cttgcaactg catttcgata caaatgagct agtcatcagc aaggaaagca aggagctgac
    34021 ccgcatctct taccgagcca ttcagactga gagtttcaaa agcaaagaca gcttgaccca
    34081 agcaatttct aaagactggt accaacaaaa tcgtgtctat atcagcctct tcctagttct
    34141 cggtgcgagc ttcctctttg gtttgaattt ctttatcgtc tctctaggag ctagtcttct
    34201 cctttatatc actaagaaat cacgcctctt ttcatttaga acctttaaag agtgctatca
    34261 ctttatcttg aactgtttag gattgccgac tctgattaca cttattttgg gattatttgg
    34321 ccaaaatatg acaaccctga ttactgtaca aaatattctt tttgttctgt atctggtcac
    34381 tatcttttat aaaacacatt tccgtgatcc aaattaccat aaataggaga tttttatgcc
    34441 cgttacgatt aaagacgtgg ccaaggctgc tggtgtttcg ccttcaaccg taacccgtgt
    34501 tattcaaaat aaatcaacca ttagcgacga aacaaaaaaa cgcgttcgca aagctatgaa
    34561 ggaactcaac taccacccaa acctcaacgc tcgtagcttg gtaagcagct atactcaggt
    34621 tatcggatta gttcttcctg atgactcaga cgccttctac cagaatcctt tctttccatc
    34681 ggttctacgt ggcatctctc aagtcgcatc tgaaaaccac tatgccattc agatagcaac
    34741 agggaaagat gagaaggagc gtctcaacgc tatttcacaa atggtctacg gcaagcgtgt
    34801 agatgggcta atctttctct atgcccaaga agaagaccct ctcgtaaaac tcgtcgcaga
    34861 agaacagttc cccttcctta tcttaggtaa atctctatct cctttcatcc cacttgtcga
    34921 caacggcaat gttcaagctg gttttgatgc gactgaatat ttcatcaaaa aaggctgcaa
    34981 acgcattgcc tttatcggag gaagtaaaaa gctcttcgtg accaaagacc gtttaacagg
    35041 ctatgaacag gcgcttaaac attacaaact taccactgac aacaatcgca tctactttgc
    35101 cgacgagttt ctggaagaaa agggctataa atttagcaag cgattattca agcacgatcc
    35161 acaaattgat gctatcatca caaccgatag cctcctagct gaaggtgttt gtaactatat
    35221 tgccaaacac cagctggatg tccctgttct cagctttgac tcggttaatc ccaagctcaa
    35281 cttggcagcc tatgtcgata tcaatagttt agagcttggt cgtgtttccc ttgaaactat
    35341 tctccagatt attaatgata ataaaaacaa taaacaaatt tgttaccgtc aattgatcgc
    35401 ccacaaaatt atcgaaaaat aagagactgg gcaaagagtc gttaaaagca aaaacgcata
    35461 ctatcaggta ttgaaaaaac ttgatactat gcgtttta
//
LOCUS       DAVBNZ010000017        34124 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000017 DAVBNZ010000000
VERSION     DAVBNZ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.017"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(21..833)
                     /locus_tag="VQ860_000871"
     CDS             complement(21..833)
                     /locus_tag="VQ860_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3119322.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            1023..2441
                     /locus_tag="VQ860_000872"
     CDS             1023..2441
                     /locus_tag="VQ860_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET3119323.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            2494..3201
                     /locus_tag="VQ860_000873"
     CDS             2494..3201
                     /locus_tag="VQ860_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3119324.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGISIVVLVLFIIGARKTQLASFNFSFFRTKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            3297..4277
                     /gene="folP"
                     /locus_tag="VQ860_000874"
     CDS             3297..4277
                     /gene="folP"
                     /locus_tag="VQ860_000874"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET3119325.1"
                     /translation="MMKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFVLEQ
                     ALQQARKLIAEGASMLDIGGESTRPRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTRKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQTFTEKELADFETLPIEEMMEAFFERALARAAEAGIAPENILLDPGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            4279..5601
                     /locus_tag="VQ860_000875"
     CDS             4279..5601
                     /locus_tag="VQ860_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3119326.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLALLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLDQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            5582..6136
                     /gene="folE"
                     /locus_tag="VQ860_000876"
     CDS             5582..6136
                     /gene="folE"
                     /locus_tag="VQ860_000876"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET3119327.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIESEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            6179..6991
                     /gene="folK"
                     /locus_tag="VQ860_000877"
     CDS             6179..6991
                     /gene="folK"
                     /locus_tag="VQ860_000877"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET3119328.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(7036..7353)
                     /locus_tag="VQ860_000878"
     CDS             complement(7036..7353)
                     /locus_tag="VQ860_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET3119329.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            7710..8156
                     /gene="rplM"
                     /locus_tag="VQ860_000879"
     CDS             7710..8156
                     /gene="rplM"
                     /locus_tag="VQ860_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET3119330.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ860_000880"
     CDS             8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ860_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET3119331.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(8829..9251)
                     /locus_tag="VQ860_000881"
     CDS             complement(8829..9251)
                     /locus_tag="VQ860_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3119332.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            9398..9574
                     /locus_tag="VQ860_000882"
     CDS             9398..9574
                     /locus_tag="VQ860_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119333.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            9976..12189
                     /locus_tag="VQ860_000883"
     CDS             9976..12189
                     /locus_tag="VQ860_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HET3119334.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12411..12887)
                     /locus_tag="VQ860_000884"
     CDS             complement(12411..12887)
                     /locus_tag="VQ860_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET3119335.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            13110..16313
                     /locus_tag="VQ860_000885"
     CDS             13110..16313
                     /locus_tag="VQ860_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET3119336.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSSWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKGGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKKLESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ860_000886"
                     /pseudo
     CDS             16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ860_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17456..18085)
                     /locus_tag="VQ860_000887"
     CDS             complement(17456..18085)
                     /locus_tag="VQ860_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET3119337.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(18095..19096)
                     /locus_tag="VQ860_000888"
     CDS             complement(18095..19096)
                     /locus_tag="VQ860_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET3119338.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(19127..19768)
                     /locus_tag="VQ860_000889"
     CDS             complement(19127..19768)
                     /locus_tag="VQ860_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET3119339.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(19787..20602)
                     /locus_tag="VQ860_000890"
     CDS             complement(19787..20602)
                     /locus_tag="VQ860_000890"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET3119340.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIKAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEIGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            20873..21307
                     /locus_tag="VQ860_000891"
     CDS             20873..21307
                     /locus_tag="VQ860_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3119341.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            21319..22509
                     /locus_tag="VQ860_000892"
     CDS             21319..22509
                     /locus_tag="VQ860_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET3119342.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEYYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22520..23011
                     /locus_tag="VQ860_000893"
     CDS             22520..23011
                     /locus_tag="VQ860_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3119343.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            23026..23805
                     /locus_tag="VQ860_000894"
     CDS             23026..23805
                     /locus_tag="VQ860_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3119344.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            23792..24610
                     /locus_tag="VQ860_000895"
     CDS             23792..24610
                     /locus_tag="VQ860_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3119345.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            24610..24903
                     /locus_tag="VQ860_000896"
     CDS             24610..24903
                     /locus_tag="VQ860_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3119346.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            24925..26826
                     /locus_tag="VQ860_000897"
     CDS             24925..26826
                     /locus_tag="VQ860_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET3119347.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALIQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            26886..27887
                     /locus_tag="VQ860_000898"
     CDS             26886..27887
                     /locus_tag="VQ860_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3119348.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(27997..28332)
                     /locus_tag="VQ860_000899"
     CDS             complement(27997..28332)
                     /locus_tag="VQ860_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119349.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLSNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28343..28585)
                     /locus_tag="VQ860_000900"
     CDS             complement(28343..28585)
                     /locus_tag="VQ860_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119350.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28596..29138)
                     /locus_tag="VQ860_000901"
     CDS             complement(28596..29138)
                     /locus_tag="VQ860_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET3119351.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQKVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYLGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(29154..29348)
                     /locus_tag="VQ860_000902"
     CDS             complement(29154..29348)
                     /locus_tag="VQ860_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3119352.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ860_000903"
     CDS             29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ860_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET3119353.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ860_000904"
     CDS             30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ860_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET3119354.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ860_000905"
     CDS             30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ860_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET3119355.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            33051..34031
                     /locus_tag="VQ860_000906"
     CDS             33051..34031
                     /locus_tag="VQ860_000906"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET3119356.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGIIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
BASE COUNT        10306 a         6070 c         7606 g        10142 t
ORIGIN      
        1 tcattgagta tcagtatagg ttataagaat aagtcttgta gggttttggc aaccccatct
       61 tggtcgttgg taagggaaat ttgctcatct gcataaggga gtagctctgg attggcattt
      121 ttcatggcat aacccttccc agcaaaagcg agcatttcgg tatcattgtg ttcatctcca
      181 aaggcaatca aatctttttt gtcacgattc attatcttga gcaagtagtc caaagcaaag
      241 gccttgttga caccttttgg ggtacattca aggatattga gcggacctcc ccaggtattg
      301 atagaaagtt gatgctggta gaaggcgttc atgtcttttg ccaaggcata tttgtcactg
      361 gctctggtct gcaagaggat acagttaggg tccttggtca ccaattcagg ctggaattga
      421 tcttcaggct ggaaagcttc tacaccaaat agtttgggat tggcaatttc ttcattggga
      481 tttgtaatgt agaatttttt acgatattct ccagcgataa aatcggcttg aatgtcctct
      541 gaacgttgaa ccatatctag cagatatttt ttgtctacag tcaaacactt ttcaaaatcc
      601 caaacttggt ctggtaaatg agtaagggat ccgttgaagt taatcatagg agtgtctaag
      661 cccagttcac ggtaaaaatc ttttgacata cggtaagggc gacctgtcgt aataataacc
      721 tgatggcctt tttcagcaac ttttttgatg gtttttttgg taaagtcaga aatttgactg
      781 tctgagttga gcagggttcc atccaggtca actgcaataa tttttttcgt catatggacc
      841 tttctagtgt gttttcagat aagatgtctt ctattataac agaaagcagg cagaaaagca
      901 gattccaaac aaaaaatgaa attggattaa tttcttaaac aaatcaaaca aagacattga
      961 aaaagtgaat gataaatgat ataattctat tattgttcgt aaaaattaaa aggagattga
     1021 tgatggacaa attatttaaa ctaaaagaga acggtacaga cgttcgtaca gaggttctcg
     1081 ctggtttaac aactttcttt gcaatgagct atattctctt tgtaaaccca caaatacttt
     1141 cacaaacagg aatgcctgct cagggcgtct tcctagcgac gattattggt gcagtagcgg
     1201 gtaccctgat gatggctttt tatgctaact taccttatgc ccaagcgcca ggtatgggac
     1261 tcaatgcctt ctttaccttt acagttgtat tcgggcttgg ttattcttgg caagaagccc
     1321 tagctatggt cttcatctgt gggattattt cattgattat taccttgaca aatgttcgta
     1381 aaatgatcat tgaatcgatt cccaatgctc ttcgctcagc tatttcagct ggtatcggtg
     1441 tcttccttgc ctatgtaggg attaagaatg ctggactttt gaaattcacg attgatccag
     1501 gcaactatac tgttgtagga gaaggggctg acaaagctca agcaacgatt gcagcaaact
     1561 cttcagcagt tccaggattg gtcagcttta ataatccagc tgttttagtg gctcttgcag
     1621 gacttgccat tactatcttc tttgtcatca aagggattaa agggggaatt attctctcta
     1681 tcttgacaac aactgttctt gctattgcag ttggtttggt tgatttgtct agtatcgatt
     1741 ttgctaataa ccatgttggt gcagcttttg aagatttgaa gacaatcttt ggtgcagctc
     1801 ttggttcaga aggattggga gctttggttt cagatacagc tcgcttgcct gaaactctga
     1861 tggccattct tgccttctca ttgacagata tttttgacac aattggtacc ttgatcggta
     1921 caggtgaaaa agttggtatc gtagcgacaa atggtgaaaa tcaccaatca gccaaattgg
     1981 ataaggctct ttactctgat ttgattggaa cgacagtcgg tgccattgca ggtacttcaa
     2041 acgtaacgac ttatgttgag tctgctgctg gtatcggtgc tggtggacgt actggtttga
     2101 cagccttggt tgtagctatc tgttttgcga tttcaagctt ctttagccca cttctagcga
     2161 tcgtaccaac agcggctaca gctccaatct tgattatcgt tgggattatg atgcttggta
     2221 gcttgaaaaa tatccattgg gatgatatgt ctgaagcagt tcctgccttc ttcacatcta
     2281 tctttatggg attcagctac tctatcactc aagggattgc agttggtttc ttgacttaca
     2341 ctttgactaa gcttgttaaa ggtcaagtta aagatgttca tgtcatgatt tggattttgg
     2401 atgccttgtt tatccttaac tacatcagca tggccttata atagaatgac ccagggggat
     2461 ttcccccctt ttttaataca aaggagatag gtgatgaaag agaaaaatat gtggaaagaa
     2521 ttgttgaatc gtgcaggctg gattttggtc tttttacttg ccgtcctttt atatcaggtt
     2581 cccctagtgg ttacctctat tttgacttta aaagaagtag ccctgctaca gtcagggctg
     2641 atagttactg gtatttctat tgtggttctg gtgctattta ttattggagc tcgtaaaacg
     2701 caattggcaa gttttaattt ttcttttttt agaactaagg atttggcacg tttgggcttg
     2761 agttatttag tcattatctg ttcaaatata cttggttcta tcttgttgca actgtcaaat
     2821 gagacgacaa cagctaacca gtctcagatt aacgatatgg ttcagaatag ttctctgatt
     2881 tctagcttct tcttgctagc cttgcttgct ccaatttgtg aggaaatctt gtgccgtggg
     2941 attgttccta aaaagatttt ccgaggcaag gagaacttgg gatttgtagt cggtacgatt
     3001 gtgtttgctt tattgcatca accaagtaat ttaccttctt tattgattta tggaggtatg
     3061 tcgacagttc tatcttggac ggcctacaag acccaacgtt tggaaatgtc gatcttgctt
     3121 cacatgattg ttaatgggat tgctttctgt ttgttggctc ttgtggtgat tatgagtcgg
     3181 acattaggaa tttctgttta aaagttttta tgtaggaacc gacctctttc tactgggaaa
     3241 aagatgaatg caatcgtgtc catctttttc tttttatggt aaaatagaga aataatatga
     3301 tgaaaagcct tgagggagtg accgatatgt caagtaaagc taatcatgca aagacagcta
     3361 tttgcggaat tatcaatgta accccagatt ccttttcgga tggtggtcaa ttttttgttc
     3421 ttgagcaagc gctccagcag gctcgtaaat tgatagcaga aggagccagc atgctagata
     3481 tcggcggtga atcgactcgg cctcggccgg gaagtagcta tgttgagata gaagaggaaa
     3541 tccagcgtgt tgttccagtg attaaagcga ttcgcaagga aagtgatgtc ctcatctcta
     3601 ttgatactcg gaagagtcag gtggcagagg ctgctttggc tgctggtgcc aatctagtca
     3661 atgatatcac tggtcttatg ggtgatgaga aaatggccca tgtggttgct aaggctggtg
     3721 cgaaagtagt cattatgttt aacccagtta tggctcggcc tcagcatcct agttcgctta
     3781 tcttccctca ttttggtttt ggtcaaacct ttacagaaaa agagttagct gactttgaaa
     3841 cattgccaat cgaagaaatg atggaggctt tctttgaacg agcactagcg agagcggcag
     3901 aagctggtat tgcaccagaa aatatcctgt tggatccagg aattggcttt ggtctgacca
     3961 agaaagaaaa tctgcttctt ttacgggacc tggataaact acatcagaag ggctatccaa
     4021 tctttctcgg agtgtcgcgc aagcgatttg tcatcaatat cctagaggag aatggttttg
     4081 aagtcaatcc tgagacagag cttggtttcc gaaatcggga cacggcttcg gctcatgtaa
     4141 ctagtatcgc tgcgagacag ggtgtagaag tggtgcgcgt gcatgacgta gctagtcaca
     4201 ggatggcagt tgaaattgcc tctgccattc gtctggctga tgaagcggaa aatttagatt
     4261 taaaacaata taaataagat gaaagaaatt gaaaacaatc agtggattgc taactaccgg
     4321 acggatcaac cgcattttgg cttggaacga atggtggaac tgttagcttt gcgtggcaat
     4381 ccccatctca aactcaaggt cctccatatc ggagggacta acggcaaggg ctcgactatt
     4441 gcttttttga aaaagatgct agaaaagcta gggctgagag ttggcgtgtt tagctcgccc
     4501 tatctcattc attacacaga ccagattagc atcaatgggg aatcgatctc agaagcgagg
     4561 ctagaagctc tcatggcaga ttatcagtct ttgctggagg gagaagcggt cgccaattta
     4621 cagggcacaa ccgagtttga gattatcaca gccctggcct atgactactt tgcctcagag
     4681 caagtagatg tggccatcat ggaagttggc atgggtggac ttttggatag taccaatgtc
     4741 tgtcagccca ttttgacagg aattacaact attggcttgg atcatgtggc cctacttggt
     4801 gacaccttgg aggccatagc agagcagaag gcaggtatta tcaaacaagg gatgcccttg
     4861 gtaacagggc gtattgctcc agaagccttg actgtgattg accgcattgc ggaagggaaa
     4921 gatgcgccga gacttgccta cgggacagat tatcaggttc gtcatcaaga aagtgtggtg
     4981 acaggggaag tctttgacta tacaagtgct gtcagacaag gtcgcttcca gactagcctg
     5041 cttggtttgt accaaataga gaatgctggg atggccatag ctttacttga tactttttgt
     5101 caagaagatg gtcgagagct agcaagcaat gactttcttg gtcaagcctt ggaagaaaca
     5161 agttggccag ggcgtttgga aatcgtgtca agagatccct tgatgatttt ggatggagcc
     5221 cacaatcccc atgctatcaa ggccttgttg gtaaccttgc aagaacgttt tgcagattat
     5281 cataaggaaa tcctcttcac ttgtatcaaa accaaggcct tggaggatat gttggccttg
     5341 ttgggagcca tgccagatac cgagcttact ctaacacatt ttgcggatag tcgggcgacg
     5401 gatgaaagcg tgctgaaaga ggcagctaag tctagaaatc tcagctacca agattggcat
     5461 gattttctag atcagaattt gacagataaa aaagaagaga aacaaacagt taggattgtc
     5521 acaggttcct tgtatttctt gagccaagtg agggcctatc tgatggagag gaagaacgag
     5581 aatggataca caaaagattg aagcagctgt aaaaatgatt atcgaggctg taggagagaa
     5641 cgctaatcgc gagggcttgc aggaaacacc tgctcgtgta gcccgtatgt atcaagagat
     5701 tttttcaggt cttggtcaaa cagcagagga acatttgtca aaatcctttg aaattattga
     5761 cgataatatg gtggtagaaa aggatatctt tttccatacc atgtgtgaac accacttctt
     5821 gccattttat ggtagagcgc acattgccta cattccagat ggtcgtgtgg caggcttgtc
     5881 taagctagcc cgtacggttg aagtttattc gaaaaaacca caaattcaag aacgtttgaa
     5941 tatcgaagtg gccgatgcct tgatggacta tctaggtgct aaaggagcct ttgttgtcat
     6001 tgagtcggaa catatgtgta tgagtatgcg tggtgttaga aaaccaggca ctgcaacctt
     6061 gacgacagta gctcgtggtt tatttgaaac agataaggac ctccgcgacc aagcttatcg
     6121 tttaatgggg ctataaaaag aatccgcttc aagcggattt ttctagaaag gaatcattat
     6181 ggatcaactg cagattaagg atttggaaat gtttgcctat catggtcttt ttcctagtga
     6241 gaaagaattg gggcagaaat ttgtcgtttc agccatccta tcctatgata tgaccaaggc
     6301 agctacagac ttggatttaa cagcctctgt ccattacgga gaattgtgtc agcagtggac
     6361 gacttggttt caggaaacga gtgaggattt gattgaaacg gtagcctata aactggtgga
     6421 acgtaccttt gagtcttatc ctcttgtcca agaaatgaag ttggaactga aaaaaccttg
     6481 ggcaccggtg catttgtcac tagatacttg ctcggtaacc attcatcgcc gcaagcaacg
     6541 agcctttatc gccctaggaa gcaatatggg agataagcaa gcaaacttga agcaagccat
     6601 tgacaaactg cgagctcgtg gcatccatat tctcaaagag tccagtgtct tagcgacgga
     6661 gccttggggt ggagtggagc aggatagctt tgccaatcaa gtggttgagg tggaaacctg
     6721 gctaccagca caagacttgt tagaaacctt gttagccatt gagtcagagc tgggacgggt
     6781 gagagaagtg cattggggac ctcgtttgat tgatttggac ttgctctttg tggaggacca
     6841 gatcctttat acagacgacc tcatattgcc tcatccttac atagcggaac gcctttttgt
     6901 ccttgagtcc ttacaggaaa ttgcgcctca ttttatccat ccgatattaa aacaaccgat
     6961 ccgcaacttg tatgatgctt tgaaaaaata gaaaaactct agttttcagt tacttgcaac
     7021 tgaaggctag agtttttaaa ataggtcatt ttcttctggg aggaggatag tttctctacc
     7081 gtccatgtct aaaaccagta ctcttggggg ataacgaggg tcgaaaggat ggttaaagtc
     7141 aaaatcaatg gctgtaggga ggtgttgact tgaaaagtgg aaggtaatct ttccttggtt
     7201 attaagcaat tgaaactcga gttcttcttc caattcaaag acatttttta agaaatgatc
     7261 gatgatatac caaaaagagt caatgatgtc atcaggcaag ctggtaacaa tgccaaaact
     7321 agcagaccgc atgtgggtat tggtaaaagc catatctctg tcccctttct tttcccttat
     7381 catacagcaa ataggattaa aaatcaagaa aaggtgattt tttgaaaagg attttaacta
     7441 cagggaaaaa gaaggaaaaa aattcccaaa aatctaccga agttaatagg taaattccca
     7501 aattaacttg attatataac tttcagttac tttgagaagt taccgaaaaa tatttttcat
     7561 atctattgac ttttaggggt gaaatttggt atgatagtag gcggtattgt ttaccccatt
     7621 tgaaaggccc cggaaccttc caaatacttt tcgatgggaa ggaacaccca tcaccgtaaa
     7681 caaaaatcga actatatata ggagaaatca tgaacaaaac aacatttatg gctaaaccag
     7741 gccaagttga acgtaaatgg tacgtagttg acgcaactga tgtaccactt ggacgtcttt
     7801 ctgcagtagt tgctagcgta cttcgcggaa aaaacaaacc aacatttaca ccacacactg
     7861 atacaggtga cttcgtgatt gttatcaatg ctgaaaaagt taaattgact ggtaaaaaag
     7921 caactgataa aatctactac actcactcaa accacccagg tggattgaaa caaatctctg
     7981 caggtgaact tcgttctaaa aatgcagtac gtttgattga gaaatcagtt aaaggtatgc
     8041 ttccacacaa tacacttgga cgcgctcaag gtatgaagtt gaaagtattt gttggagctg
     8101 agcacactca cgctgcacaa caaccagaag ttcttgacat ttcaggactt atctaaggaa
     8161 aggaacaata aagtatgtca caagcacaat atgcaggtac tggacgtcgt aaaaacgctg
     8221 ttgcacgcgt tcgccttgtt ccaggaactg gtaaaatcac tgttaacaaa aaagatgttg
     8281 aagagtacat cccacacgct gaccttcgtc ttgtcatcaa ccaaccattc gcagttactt
     8341 caactgtagg ttcatacgac gttttcgtta acgttatagg tggtggatac gctggtcaat
     8401 caggagctat ccgtcacggt atcgctcgtg cccttcttca agtagaccca gacttccgcg
     8461 attcattgaa acgcgcagga cttcttacac gtgactcacg taaagttgaa cgtaagaaac
     8521 caggtcttaa gaaagctcgt aaagcatcac aatttagtaa acgttaattc gaaagaatta
     8581 ctatacttat acagagcacc tttcggggtg ttcttttttt atactttctt actaaattgg
     8641 tgcaattgac acagttgttg cgactttagt cgcttacaaa tgtggctgca acctgacaag
     8701 gtcagttgcc tcaaaacgtt aatcaataca attatatcaa cgtttcaaag cactcaagag
     8761 tttacctcat gggtgctttt tttatgtttt ttgaaaaagt tcacctcaaa gtttacctta
     8821 ttttcacctt attgttttag agactgtaag gcaaattcac cgacggccat agggactaca
     8881 ttagaagtat tgacataaat ctgtgttgta cctgtgtcgc tatgtattag agcttcagaa
     8941 atggcttcta agctcattcc tgcttgttta gcgagcgttg ctccggtatg acgtagtttg
     9001 tgtggcgtag cgtgtgtaag ctctgggtgt cgttttctga tagttttcat cttattattg
     9061 agatagtcag aatgtaaagg tttattgata ttgcctttgg tatctatgta agtaaagatg
     9121 aattgttctg gattactgat gataccaaac tttgccagtt catatttttg ttgttttttc
     9181 catgaagtca gaagttgaag taagtcatta gaaatagaga aaatgggaaa tgtttccaca
     9241 ataaaacgca tattatcaga tggttaatgc gttttatatt tgggtttgag gcttataaaa
     9301 taggataagc gtactgaaaa cttagatatg acaaacaaaa taaaattttt aaaagctaca
     9361 gagaaacatg gtataatgta tctaaaggag gtagcatatg tccttagata tagataaaga
     9421 aaagatgaca atcatgggaa tagcttttga aaaccgatcc gtttttaaga gtgtttggta
     9481 tgctttaagt acaaatatga ttgaaggatg gcgacctacg gttagtgatg ttgaaaaatt
     9541 acgagatgaa gctcttgctc tggggatgac ttaatgaagc gcaactgtta tgaatcttat
     9601 gactatgttg atccggataa tttatatacc gatccgggtt cttcagttct aagaaataag
     9661 caggaaggaa aaaagcacgc gagcttgaat atcgtatgat tgctagtaag agtttgaaat
     9721 tatttatcaa tcctatctta gttaatagtt taaaagtagt ttgtttcaca actgcataag
     9781 cttagaaaag ttgaaaagtg ataactcttt aataaactct tggtttgtta aaagatattt
     9841 tgtccactac atttttttca attgactatt atttgtcata gatataacag atagaacatt
     9901 gcattcagaa taatgaaaaa cgcatcaaaa atggtgcgtt ctgtttttat gctaccataa
     9961 aaggaggaaa acaaattgaa aatttttaag ggagagtttt atcgaatctc tgtattaaca
    10021 gacaagctag taaggttaga atactctcga actggaaatt ttgaggatag aacgacacaa
    10081 cttatctata atagagattt tggccaagtt tcgttagatt atatcgagac atcaaatgta
    10141 ctagatatta tgacggacta ttttcatctg cactttaata aaggagaatt taacgccgaa
    10201 aatttattta tagaattaaa aggaaatttt gccgtatatg gtagtcgctg gtattttggt
    10261 gaatctattg aaacgttaaa aggaacagct cggactctgg ataaggcaga tggagcaatc
    10321 tcgttagaag atggaattat tagccgaaat ggtatagcct tattggatga ttctcaagga
    10381 tttatttggg atgaacaatc tggttatatt gagagagaaa atcaaattga cctgtatttc
    10441 tttgcctatg ggcatgatta tagaggagca atcagagact tttaccattt gactggttca
    10501 acacccttgt tgccaagata tgctttaggc aattggtgga gtagatattg gccttatacg
    10561 tcggatgaat acttggattt aatagacaga tttgaaacag agaaaattcc attatctatc
    10621 ggtgtgttag atatggattg gcatataact gacattccag ctcgttttgg aagtggctgg
    10681 acaggatata gttggaatag aaacttaata ccaaatccag aacagttatt gcaacaactt
    10741 catgatagaa agttaaaact ctccttaaat gtccatcctg ctgatgggat acgggcttat
    10801 gaagaagctt atcctcaaat cgcaaaacgg ttggggttaa atgtagaact agaagaacct
    10861 gctatttttg atttttttaa tccctctttt agggaagcct actttaaaga tgttcattat
    10921 gagctagaaa agcagggagt agatttttgg tggattgact ggcaacaagg gacacaaggt
    10981 atgctagatc cactttggct tttaaaccat tatcactatc aggatagttg taaaaatgca
    11041 gaaggtggtt tgattttatc aagatatgca ggtcctggta gtcaccgcta ccctgttggt
    11101 ttttcagggg acactattat tagttggaat tccttaagat ttcaacccta ttttacagcg
    11161 acagcatcta atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg
    11221 gattatgacg aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact
    11281 cgattacata gttctagaag tccttttaat agtaaagaac cttggttctt ttcagaaaca
    11341 acatctaaga ttatgaagaa ataccttcgt ttgagacatc agatgattcc ctatctatat
    11401 accatgaatg taaagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc
    11461 tatccagaga atgatgagag ctataatgtt ccaaaccaat acttttttgg aacagaactg
    11521 atggtggctc ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta
    11581 tggttccctg aaggtgaatg gtatgacttc ttttcagaga aaaaatacac aggtggtgtg
    11641 aagttaagtg tttataggga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc
    11701 attcccttgg ttggttctga gataggtatg ggtgttgatt tacctgaggt tgtagattgg
    11761 tatgtattcc cagggaaaca acattctttt gaaatgcttg aagatcaaaa tggtcaaaga
    11821 tataaaacaa gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga
    11881 gattctagta tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatgtg
    11941 tctataattg aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa
    12001 aggacatctt taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa
    12061 ttaaaagata gattgttaaa tcaattcatc aatgccaaaa actctcatga cttaatgaat
    12121 atcttgcatc atcaggataa ggaattgaga gggcgtttgt tggaaatgat atttactagc
    12181 caaaactaat tgaaataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg
    12241 tattcgttat cactggtcac attgaaattg tgaaataagc acctacaaca tagactttac
    12301 aacacttcat gtttcatatc atggggtgtt tttctattta agtcaaagcc aatcaaaaaa
    12361 tctcactatt catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga
    12421 gtttgtatcg cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact
    12481 tgcccatctc gaccgatgag aaacttagcg aaattccatt cgactcgttt tcctagtggg
    12541 ccagatttct ggtcttttaa ccagacatag agagggtctg cttccttacc gttgacctta
    12601 atcttggcaa aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc
    12661 tctgcgctgc cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcgaag
    12721 ccctgatctt gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaacca
    12781 catccagtag cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt
    12841 gcttggttgt tttggttcaa aacggaaaaa tcataaagtg aagtcatgag ggcctctttt
    12901 ctttttctac attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg
    12961 aagaataagc cctcaatatg atagaaatcg tttacaaata actttaaaaa tggtatgatt
    13021 taactaaacc ggtttactta gttgctataa atctctaatt tgagatttag ttcctattga
    13081 ttttacaata tgtttattgg agtgtataca tgcaaacaaa aacaaagaag ctcattgtga
    13141 gtttgtcttc acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg
    13201 aagaaacgac tacgaatacc attcagcaaa gccagaagga agttcagtat cagcaaaggg
    13261 atacaaaaaa tttagttgaa aatggtgatt ttggtcagac ggaggacgga agcagttcgt
    13321 ggacaggaag caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag
    13381 atgcctcaac tcgagtcatt gaggctaagg atggggctat cactatctca agccatgaga
    13441 aattaagggc agcgcttcac cgtatggttc ctattgaagt taagaaaaag tataaactgc
    13501 gtttcaagat taaaacagat aataaagtcg ggattgccaa agttcgtatc attgaggaaa
    13561 gtggtaagga caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga
    13621 ccattgaagc agactatagc ccgactttag atgttgataa aatcaagctg gagttattct
    13681 atgaaacagg aactgggact gtttccttta aggatattga gctggtagag gtagcagccc
    13741 agctttctga ggattctcaa acagataaac agcttgagga aaagattgat ttaccaattg
    13801 gaaaaaaaca tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg
    13861 cttcagtcaa aaatggaatt ttagaacctc ttaagggagg gacaaccaat gtcattgtca
    13921 gtaaagatgg caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggata
    13981 catacacaga ccgtttggat gactggaatg gcatcattgc tgggaatcaa tactatgatt
    14041 ctaaaaatga acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc
    14101 tatccagtat ttcaagtcag gcggaccgca cctatttgtg ggaaaaattt tcaaattata
    14161 aaacgtctgc aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga
    14221 ccaatccttc ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca
    14281 tggaatggat gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg
    14341 attatgaaat cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact
    14401 tctctgatga ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg
    14461 aacatttccg aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata
    14521 tgggaagagt aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta
    14581 ccattcgctc gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag
    14641 atggatccta tatcgaccac accaatgttg cctatacggg tgcttatggg aatgttttga
    14701 ttgatggcct gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag
    14761 ataaaatgca aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg
    14821 gagagctgat ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg
    14881 tggccgcagt agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa
    14941 ccaaacaacg tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg
    15001 tctttaagaa tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg
    15061 caggagtcgc aagtgttcca agaccaagtt acctatctgc ctttaacaag atggataaaa
    15121 cagccatgta caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta
    15181 ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatggga
    15241 tgttctatct ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta
    15301 atccatataa gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag
    15361 gtaaagtttt accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag
    15421 caaccatgga tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc
    15481 tgaaggataa gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg
    15541 caactacaat tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg
    15601 ataaagaagc ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt
    15661 tagaatcgtc cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca
    15721 gtatgagtaa ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca
    15781 aggaagttga aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt
    15841 atggctatat gctcatccct aacgtgggtc gtgccacctt caatcaaatg ataaaaaagt
    15901 tagaaagtag cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gccaaacaag
    15961 gagtttgggg cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag
    16021 ttttgaaacg tggagtctat accattcgaa aagaagggga tgaatataag attgcctact
    16081 ataatcctga aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag
    16141 cagctcagcc acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc
    16201 attcggatca aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag
    16261 ggttcttgct acttggggca ttttatctat tccgtagagg aaagaacaac taatttgttc
    16321 atcatctaga tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat
    16381 atcttcggat ttttctttta aaaaagataa gttgatactt atctttttta cttcattatg
    16441 tgactatagc gttttgaaac tagaatagga cgttataact actaaaagat ttctataaat
    16501 tcatttgatt ttcctaatca atttgttcgt atcctatttc actccactat attagtccgt
    16561 ctcgctccgt gaggtgcgag acaaaacaac cacccgctat gcgggtgcgc gtcgaaggtt
    16621 ataccaaaaa aactctaaac gcgatacaat aaaggtgttc aatccaattg taaagcgaaa
    16681 ggagaaaaaa tatggcacaa aaggctcata gtttatctca cacaaagtgg aggtgttcta
    16741 tcacattgtg ttcaccccta agtatagacg aaaagtcatc tataatcaat atagaagtag
    16801 tttaggcgaa atatttcatc gcttgtgtag ttataaaggt gttgaaatga tcgagggtca
    16861 cttaatgcca gaccatgtac acatgttagt cagtattccg tcgaggctaa gtgtttcaag
    16921 ttttatgggg tatttaaaag gcaaaagtgc actcatgatg tttgacaaac acgccaatct
    16981 caagtacaag tttgggaatc ggcatttctg ggcggaaggt tattatgtaa gtccagtagg
    17041 gcttaatgaa gccacactta agaaatatag tcaagattaa agaaattatc cagtggatga
    17101 tttcttcacg agtatgaaaa tttgagaact agtaaagtat gatatatagt aaaatgaaat
    17161 aagaacagga caaaatcgat caggacagtc aaatcgattt ttaacaatgt tttagaagta
    17221 gaggtgtact attccagttt caatctacta tagcactaga taaattgagt gtaaaagaat
    17281 atgaggatcc ctttagggat agtggtaagt aataccaaag tatcttaaag aggcaagtga
    17341 cgagtcaaga gcaataaggc ttgaacaacg tgaaagccag cgtctttagg cgctggctgg
    17401 taatttgagc ttatagctct gggataaacc acccgtttga cgggtggtta tgattttatc
    17461 tgagtgtaat atactgttgg gcaatctcgc tgatgcggtc aaagttgcct tgggaagcga
    17521 gtttattgag ttcgccacca attccaacgg catctgcacc agcagcgaac cattgaggga
    17581 tgttgtttag gccgactcct ccggttacca ttacggaaac ttgtgggatc ggtgccttga
    17641 ctgcagagat atatgctgga ctgagagtac tacctgggaa gagtttgatg atttcactac
    17701 cggcttcaag tgcagtcgtg atctctgtga gggtaataca gcctggaatg tacggtgtgc
    17761 tgtagagatt gcacattttc gcagtttcag catggaaaga tggagaaaca acgtaatttg
    17821 ctccggctag aatggcatct ctagcagtta cggcatcaag cacagtacct gcaccgatac
    17881 aaacactctg atcgtcctga tacaagtcta caagttcctt gatgatttgc cctgcatact
    17941 gattggtata ggcgatttca atagctttga taccgccctt gatacaagca atcgaggctt
    18001 gcagtccttc ttcctttgta tttcctcgaa tgacagcgac aattttctgt ttttttagtt
    18061 caataatcgt atctgatttg gtcatgtaat tctcctaacg aatgatatct tgtgcatttg
    18121 ccagtaaatt ttcaatacta gttgcggaag tggagagatg gtctcctgga agagtgcatt
    18181 tgagagttgc gctcgcaact gcaaagtcaa tggtagtttt tagggaggaa tgatggagta
    18241 gttggtaaag ggcaccagat ataaaggcat ccccgctacc aattcgttga tagactgcag
    18301 tttttagttg gacagactct tcaaatagtt cttctagagc ataggcttga tagacatttt
    18361 tgtcttgctc atcactagag cggagggtat ggaaaatggc cttgaaacca taggcttctt
    18421 ttaaaagtcg catgcgattt tccacctctt ctaggctagc actgtctctt ggaaacatct
    18481 ctagattttg gtcatcaatc atgagaggat caataccgaa gcaatagtca gtaaaacgtg
    18541 caaacttaga aaattcatac ttggcttcta ggactgaaat catctttgtt ctcagattga
    18601 gatccattga aacgacaatt cctcggcgct tggcttcttc caagagtagg agaaggatcg
    18661 cacggacctc ttgaccgata gctacggtga ttccactaaa atgaaaatgg ctaatcccct
    18721 gaaagagaga atccatatct agcatgtttg gccgaatctg gctgatactc gtatgcttac
    18781 gatcgtagaa aacttcactt tgacgacaac caaagccgtt ctccaaatag tagaggccga
    18841 ttcgatcgcc aagccgacag attgaactgg tatcgatttg gtgctgtttc aagaatgtga
    18901 gaaaacgatc tccaatctcg ttggcaggga gtgcggtaaa gactttcgtt gagataccca
    18961 gggcttgcaa attacaagcg atgttaattt ctgatccgcc aaaataagtc gaactggcaa
    19021 catgatcgcc gatactggtg gcatctaatg gtgagattcg aattaatggt tcgccaaaca
    19081 gtaatatttt cgtcatccat tagttccttt ctggtttaga atagctttac ttagctaata
    19141 cttctttcaa ataagcagcg acttcatcat cttggcagtt ttcaaagaag tattcttgga
    19201 agtatttgcc agagatggtg tctttgagga agtcttggtc gattgtttta aggatggtca
    19261 tcaaatcatt gtgggtgatt tgtttcacct cgtttaagat acgagcgttg cgttgttcag
    19321 ggattacacg ttctcttggg tagccaccgc ccatttcttc agcaaataag cgttcaaaca
    19381 tcaatttgag ggtcagttct gccccccagc caaatccttt ggcataaggg atagacaagg
    19441 cgttaccacc attgatttga gaataaaggt aagcgtcagt tgggtccact gctagaccac
    19501 agacaacacc agggaagctg tttaaagcaa gcatagcccc tacacccgta ccacagccgg
    19561 taacaacaaa gtcaactgcc tttgtattta aaaggatggc agccattagt ccgttctgca
    19621 cataagttaa ttgactttct ccttcttctc cacgcatacc atagttaaat aattggtagt
    19681 cttttttatc tgtcgcttct tttagactat cgtaaataat gtgattcttg ctagcttgac
    19741 tattttcatt gattaatgcg attttcataa gatcttcttt ctatttttac tcaggttgtt
    19801 ttccgatgta ggctaagata ccgccatcta catataggat gtggccattg acaaaattgc
    19861 tggcatcact agcgagaaag acagcagggc ccatcaaatc ttcaggattt ccccaacgtg
    19921 cagcaggtgt ttttgcaatg atgaactggt caaatgggtg gcgagaacca tcttcttgca
    19981 actcacgaag aggtgctgtt tgaggagtgg caatataacc cggtccaatt ccgttacatt
    20041 ggatattggc tccaccgtat tcagacgcaa tgttgcgggt caacattttc aagccccctt
    20101 tagcagcagc ataagcgcta actgtttcac gtcccagttc gctcatcatc gaacaaatat
    20161 tgataatctt tccatgccct ttctttatca tagaaggaat aactgccttt gaaacgataa
    20221 atggtgcgtt taagtcaata tcgatgacct tacggaaatc agcggcgctc atttcgcaca
    20281 ttggaactcg gcggataata ccagcgttat taacgaggat gtcaatgaca ccaatctctt
    20341 gttcgatttg cttgaccatg gcttggatac cgtcctcgtc tgtcacgtca cagacatatc
    20401 catgggcttc gatgccaact tcacgataag ctttaatccc tttattgacc agatcttgat
    20461 tgatatcgtt aaagacaata gtagcgccgg cttcagcgta ggatttggca atagcaaatc
    20521 caattccata agaagcgccg gtgatgaggg caatttttcc ttttaaagaa aactgctcaa
    20581 ttgagaatga tgtatttgtc atttgatact tcctttcaaa tttgttaaga cttctctata
    20641 accaaattat attctagtaa accggttttg tcaataaata aatattttta tttataaaaa
    20701 gatttatttt ccttaaaaat ggaatatttt gaaatttctg tctattaaaa tgattaaaaa
    20761 gataatgaaa gcgctaatat ttttttaaaa aaactattga caagataaaa ataaaggatt
    20821 acaatgggga atataaagta aaccggtaaa cctaaacaag aaaggagaaa agatgaaaat
    20881 tgtacttgta gggcatggac attttgctac agggatttat agttctttac aattgattgc
    20941 aggcaatcaa gaaaatgtgg aggcaattga ctttgtggaa ggaatgtcag cagatgaact
    21001 caagcaaaaa atcttacttg caatttcaaa tgaagaagaa gttttaatcc taagtgatct
    21061 cttgggagga tcgccattca aggtttcttc taccataatg ggagaaaatc cagccaaaac
    21121 aatgaatgtt ctctcgggtt tgaacttagc catgttaatg gaagcagtct ttgctagaat
    21181 ggctcatagc tttgatgagg ttgttaataa atcagtagtg gcggcccagg gcggagtcgt
    21241 aaatggtaaa gaattgtttt caacggatgc agaggaagag gaagaagatt tcgaatcggg
    21301 tatttaaagg gtaaaagaat gataaaaaag gttacgattg aaaaaataaa atcgcctgag
    21361 cgcttcttag aagtaccact tctgacgaaa gaagaagtcg gccaggcaat cgataaggtt
    21421 attcggcagt tagaactcaa ccttgactat ttcaaggaag atttcccgac gccagctacc
    21481 tttgataatg tctatccaat catggataac acggaatgga ccaatggttt ctggacagga
    21541 gaactgtggt tggcttatga atacagtcaa caggatgcat ttaaaaacat cgctcataaa
    21601 aatgttcttt ctttcctgga tcgtgtcaat aagagagtag aattggatca ccatgatctc
    21661 ggcttcttgt acacaccgtc ttgtatggct gaatataaga taaatggaga tggagaggct
    21721 agagaagcag ccttgaaagc tgcagataag ttgattgaac gctatcaaga aaaaggtggt
    21781 tttattcaag cttggggaga cttgggcaag aaagagcatt accgtttgat tatcgactgc
    21841 ttgctcaata tccaactctt attctttgct tatcaagaaa caggcgatca aaaatactac
    21901 gatattgcag aaagccattt ctatgcttca gctaataatg taatccgtga tgacgcttcg
    21961 tccttccaca ccttctattt tgatcctgag acaggtcaac cctttaaagg tgtaacgaga
    22021 caagggtata gtgatgattc atgctgggca cgtggtcaat catggggagt ctatggtatt
    22081 cctttgactt atcgtcactt aaaagacgag tcctgctttg acttgtttaa gggtgtgacc
    22141 aattatttct tgaatcgtct gccaaaagat catgtgtctt attgggattt gatttttaat
    22201 gatggtagtg atcaatcacg agattcttca gcaacagcta tcgccgtctg tgggattcat
    22261 gaaatgctaa aacatctccc agaggtggat gctgacaaag atatttataa acatgctatg
    22321 catgccatgc ttcgttcctt gatcgaatat tatgcaaatg atcaatttac ccctggtggg
    22381 acaagtctcc tccacggtgt gtactcatgg cattcaggta aaggagtgga tgaaggcaat
    22441 atctggggtg actactatta cctagaagcc cttatccgtt tctacaaaga ctggaaccta
    22501 tattggtagg aggagaaata tgacaatgcc aaatattatt atgacccgta tcgatgaacg
    22561 gttgattcat ggacaaggac aactttgggt aaaataccta ggttgtaata cggtcattgt
    22621 tgccaatgac gaagtaagca cggacaagat gcaacaaact ctgatgaaaa cagttgtgcc
    22681 agactcagtt gccatgcgtt tcttcccttt gcaaaaggtg attgatatca ttcacaaggc
    22741 taatcctgct caaacgatct ttatcgttgt aaaggatgta aaggacgctt taaccttggt
    22801 agaaggtggt gtccctatca aagaaatcaa tattgggaac attcacaatg cccctggtaa
    22861 agagcaagtg acacgctcca tcttcctggg tgaagaggac aaggcagccc tcaaggaatt
    22921 aagccaaact catcaagtaa catttaatac gaaaacaact ccaacaggaa atgatggagc
    22981 tgttcaagtc aacattatgg actatattta aaagaggaga tcgttatgtc gattaatgta
    23041 tttcaagcga ttttaattgg attatggaca gctttctgtt ttagtggaat gctgttagga
    23101 atttacacca atagatgtat tgttctgtca tttggtgtcg gaattattct aggtgatctg
    23161 cctactgctc ttgcaatggg agctattggt gaattggctt atatgggatt cggtgttggt
    23221 gctggaggta ctgttccacc aaacccaatc ggacctggta tctttggtac cttgatggct
    23281 atcactagtg ctggtaaagt cagtccagaa gcggctcttg ccctctctac tccgattgct
    23341 gtggcgattc aattcttaca aactttcgcc tacactgtac gtgctggtgc gcctgaaacg
    23401 gcgatgaagc acttgaaaaa ccataatttg aagaaattca agttcactct aaatgcaaca
    23461 atttggttgt ttgcctttat tggatttacc ttgggttgct tgggtgccct ttcaatggat
    23521 accttgttga aactcgtaga ctacattcca ccggtattac ttacaggttt gacagttgct
    23581 ggtaaaatgc tcccagctat cggttttgcg atgatcttgt cagtgatggc taagaaagag
    23641 ttgattccct ttgtcttgtt gggatatgtt tgtgcagctt atctaaacat cccaacaatt
    23701 ggtattgcaa ttgtaggtac tatctttgct ttgattgaat tttataacaa gccaaaaaca
    23761 gcggatcatg tggtagagga ggaagcacac gatgactgga tctaacaaat taacaaaacg
    23821 tgattatctt aaaacgtctt tgcgggcatt cttttgtcaa aatggattta actatagtaa
    23881 ctatcaaggg ttgggatatg ccaatgtaat gtatcctgct ttgaaaaaac actatggaga
    23941 ggatcaggaa ggtttctacc aagccttgga agaaaactgt gaattctata ataccaatcc
    24001 acacttcctg ccttttatta ccagcttgca ccttgtaatg ttggaaaatg gccgtccggc
    24061 aaaagaaaca cgtagcatca agatggcctt gatgggacca ttggcaggta ttggggattc
    24121 tctttctcaa ttctgtttag ctccattgtt ctcaaccatc gcagcttcgt ttgctcaaga
    24181 aggcttggtt gtcggtccaa tcttgttctt ccttgcgatg aatacgattt taacagcgat
    24241 taaattgtca actggtctgt atggatacaa actaggaaca actgtgattg ataaactaag
    24301 cgaacagatg gcaacgattt ctcgtattgc caatattatc ggtgtaaccg taattgctgg
    24361 tttggcagcg acatctgtta agattatggt gccgattacc tttgctgcag gggaagttaa
    24421 agcagacgct aaacaaagta tcgtaagtat tcagggaatg cttgataagg ttgctccagc
    24481 tcttctacca gccctattta cacttttagt ttactacttg atcaaagaaa agaaatggac
    24541 aacatataaa ctcgttattt taacagttat catcggaatt atcggaagct ggcttaagat
    24601 tatagcttaa tggatacaac attgttttat ggaatagtga ttgtcttggc agtgagtccc
    24661 cttttactgt caagctttca ttctattcgt cagcaaaagt tgcttcgcaa acagatggag
    24721 caacgacaag agtatttagc ttctttaaca tctggtgatg aagtgttgtt attgtctgga
    24781 attcatggaa aaatcatttc tatcaaagat gacttggtct ccttgcagat tgcaaaaggt
    24841 gtggtcatct atgtagaaaa ggaaagtgta atgggaaaga caaaagaact gctttttaag
    24901 tagttctttt tctggtaata gataatgaaa gaagaaagaa gacaattttt tgaaagagtc
    24961 gatggaaacc aatgtcgtga ttatatcttg tcccactgtt caaaagacta tgagaaagtc
    25021 aagagttccc ttgaacgctt gatggacaat cgttttatgt ttgatagtcc ttgggatatg
    25081 gagccttgtt caaaaatcca tcaaatccag ccgatggtat gggatcaagt atttgaagat
    25141 gatccagaat ggtcttatat gctcaatcga caagaatatc tcttgcagtt tatgataggg
    25201 tatctggtag aaggagataa ggactatatt caaaagtgca agttctttct atttgattgg
    25261 attgagcagg tgagagaatt ttctcctcaa tccttgatga ctagaacctt ggatacgggt
    25321 attcgttcct ttacttggtt gaaactactc ttgctcctct tgaaatttga cttgctagag
    25381 gagaaagaac tagagaaaat tttggtcagt ctagaaaagc agattgactt tatgaaaagc
    25441 tactatcgcg ccaagtacac ccttagtaac tgggggattt tacaaacaat tccgatgctt
    25501 gctatctatc atttcttttc agataagatg gacctagaag aagcttacca ttttgcttca
    25561 gaggagttga aacagcaaat tgagacacag attttaggag atggaagcca gtttgaacag
    25621 tcgattctct atcatgtaga ggtttataaa gccttgctgg atttgtgtct cttgcttcca
    25681 gacttgcaag atagttacca agagttgctg gaaaagatgg cgacctatat tcaaatgatg
    25741 acaggcttag atggacggac tttggctttt ggtgatagcg attctacaga aacgacagaa
    25801 atgttgagcc tgtctgctgt ggttttgaac aaggaagacc ttcttaacgg tctggatgtt
    25861 aaagtcgatt tgcttagcct cttgttcctg gggcgagaaa aggtcaagcg actgcaggaa
    25921 tttgaaagga gagcttggca gcctaagtcc atgatctttg aagactctgg acatgtctgc
    25981 attaaggatg aacatcgtta tctatttttc aaaaatggtc cgctaggaag tgcccatagc
    26041 catagtgacg agaatagttt ttgcttacag tatcaaggcc aacctatttt catagatgct
    26101 gggcgttatt cttatcggga gatatatgaa cgttatctct taaagagtgc ttggagtcat
    26161 tcgacctgca ttgtagatgg gaaagctccg gaaagaatca cgggatcctg ggaatatgaa
    26221 tactatcctc actccctgtt ttgtcaccat aaagaaaggg agggagtgca ttatattgag
    26281 ggggcttatt ggtcagcaga acctgatttg ccttatcttc acaagagaaa aatcctcatg
    26341 ttggtagagg atgtctggct cttggtagat gacatcaggt gtcaaggtca gcatgaggcg
    26401 ttgattcagt ttatccttga caaggatgtg acctatcaag atgggaaaat caatcagttg
    26461 agactatgga gtgaagttga ttttgatttg gaagatacca tcatttctcc taaatacaat
    26521 gagcttgaaa gaagtagcaa gctcaccaag cgccaattct ttgagaatca gatgctggat
    26581 tataccatca ttgcgcatga gagttttgaa atcatccgtc attctgtcta ccagacagat
    26641 gatcgtgaag tggaaaatgc tctggctttt gaagtgaaaa atgacgaaac agacaagctg
    26701 attctgttat taagcgagga tattggtgta ggtgaaaaat tgtgcctcgt tgacggaaca
    26761 aaaatgcgtg gaaaatgtct agtatatgat aaaataaatg agagaatgat tcgcttgcag
    26821 tgctagaaat aggcattttg aatagtgaat atgttataat aagtattagt aggaggtgtt
    26881 ttagattgga gaagaaactg accataaaag acattgcgga aatggctcag acctcgaaaa
    26941 caaccgtgtc attttaccta aacgggaaat atgaaaaaat gtcccaagag acacgtgaaa
    27001 agattgaaaa agttattcat gaaacaaatt acaaaccgag cattgttgcg cgtagcttaa
    27061 actccaaacg aacaaaatta atcggtgttt tgatcggtga tattaccaac agtttctcaa
    27121 accaaattgt taagggaatt gaggatatcg ccagccagaa tggctaccag gtaatgatag
    27181 gaaatagtaa ttacagccaa gagagtgagg accggtatat tgaaagcatg cttctcttgg
    27241 gagtagacgg ctttattatt cagccgacct ctaatttccg aaaatattct cgtatcatcg
    27301 atgagaaaaa gaagaaaatg gtcttttttg atagtcagct ctatgaacac cggactagct
    27361 gggttaaaac caataactat gatgccgttt atgacatgac ccagtcctgt atcgaaaaag
    27421 gttatgagca ttttctcttg attacagcgg atacgagtcg tttgagtact cggattgagc
    27481 gggcaagtgg ttttgtggat gctttaacag atgctaatat gcgtcacgcc agtctaacca
    27541 ttgaagataa gcatacgaat ttggaacaaa ttaaggaatt tttacaaaaa gaaatcgatc
    27601 ccgatgaaaa aactctggta tttatcccta actgttgggc cctacctcta gtctttaccg
    27661 ttatcaaaga gttgaattat aacttgccac aagttgggtt gattggtttt gacaatacgg
    27721 agtggacttg cttttcttct ccaagtgttt cgacgctggt tcagccctcc tttgaggaag
    27781 gacaacaggc tacaaagatt ttgattgacc agattgaagg ccgcaatcaa gaagaaaggc
    27841 aacaagtctt ggattgtagt gtgaattgga aagagtcgac tttctaaaat gaaggaaaat
    27901 gacttgcaat ctctgttaag aaataaaata atcccaccta gaacaagcta ggtgggatta
    27961 tttgcctatg aaatgagaaa ttatgggagc aagctcctaa atcaactgtt tttgatctac
    28021 ttctttaact acttgataaa agttatagaa gtaggccaaa cttgaaatga tggttacgac
    28081 taggaatatt gaaaatttcc attggacagg gttgcttaaa agttgtggaa aggatatgag
    28141 gagaaagaag agggctgcgt tgaggacagg tatccgtttt gattgtattt tctcaagtcc
    28201 tttattgagc gcaggaagaa agaggagtag gagtagtaaa actgtatgag aaacagctcc
    28261 tgaaataagg gcgaagaaaa ggaaaatact gataaaaaca tgaatgatca gtagtctagc
    28321 tagtgatttc ataaggcacc tcctaatcct ggtctttttt agctcttgca atacgaagtg
    28381 agtcgacaat atgtatcatc actccgaaaa agaaagctcc cagtatagtt ttaaaaatat
    28441 gttttgtatt tagaagagaa ctgataaaat ttggattttc acttgttagg gtatcaatga
    28501 gtggaattat aaaaaatatc actgttccat aaattgaacc tgctttcaga ccaggataac
    28561 gtaactgttt cttttctttt ttcatgagtt tcctcctaat cctcatcttg atttttctta
    28621 gtttttgcaa tgcgacggga gatgaggaac tgtatgctcg ctccgaagaa aatagaaccg
    28681 agaatgcttg atacaccatt tcttatagtg agaagagaat gaaaatagtc ctgaccttca
    28741 tctatgagta tactgagaag aggagttata aaaaacatcc atagaccaaa gaacaaacct
    28801 gctttaagac ctaggtagtg tagttgcttg ctttctttct cattcagcat atctggttca
    28861 atgactgtga tgcctgtttt tttcatttgg taggtgacat agccagcagc gatgagggca
    28921 atcactaaaa tcagaggagg atagattaga gccacttttt gagggtattt ataggccaga
    28981 aggagtggaa taagatttcc gaaaatcatc agataaaaga ggatgataaa gacttggttc
    29041 ccaatactat cggcctcacg ccgtttgtat tcgtcaaggg gaccagaaat accgtatgtg
    29101 cgtttgatca gtttttcagt gaaggtttct tttttcatga gtttgctcct tttttaaaaa
    29161 tcttcctccc aaaagagact gttgaggtca gtttggaggc tgcgggcgag attgagacag
    29221 agttccaagg ttggattgta cttgtcgttt tcaatcatat tgatagtctg tctcgagaca
    29281 ccgatatcct tggcgagttc gagctgggaa atacccaatt ccttgcgaaa ttctttcaca
    29341 cgattcatct gatctccttt ttgatttatg tcgtatatat ttgactttat tatagtcttt
    29401 taaacataaa gtgtcaagta tttttgacat attttttgaa gaaatagtag tctccttgtc
    29461 ctatttgtct gacaagtgca agctggtcgg atttgtggta aaatagataa gatatgacaa
    29521 aagaatttca tcatgtaacg gtcttactcc acgaaacgat tgatatgctt gacgtaaaac
    29581 ctgacggtat ctacgttgat gcgactttgg gcggagcagg acatagcgag tatttattaa
    29641 gtaaattaag tgaaaaaggc catctctatg cctttgacca ggatcagaat gccattgaca
    29701 atgcgcaaaa acgcttggca ccttacattg agaagggaat ggtgaccttt atcaaggata
    29761 acttccgtca tttacaggca cgtttgcgcg aagctggtgt tcaggaaatt gatggaattt
    29821 gttatgactt gggagtgtct agtcctcaat tggaccagcg tgagcgtggt ttttcttata
    29881 aaaaggatgc gccactggac atgcggatga atcaggatgc tagtctgaca gcctatgaag
    29941 tggttaatca ctatgactat catgatttgg ttcgtatttt cttcaaatac ggtgaggata
    30001 aattctctaa acagattgcg cgtaagattg agcaagcgcg tgaagtgaag ccgattgaga
    30061 caacgactga gttagcagag attatcaagt tggtcaaacc tgccaaggaa ctcaagaaga
    30121 agggtcatcc tgctaagcag attttccagg ctattcgaat tgaagtcaat gatgaactgg
    30181 gggcggcaga tgagtccatc cagcaggcta tggatatgtt ggctctggat ggtagaattt
    30241 cagtgattac ctttcattcc ttagaagacc gcttgaccaa gcaattgttc aaggaagctt
    30301 caacagttga agttccaaaa ggcttgcctt tcatcccaga tgatctcaag cccaagatgg
    30361 aattggtgtc ccgtaagcca atcttgccaa gtgcggaaga gttagaagcc aataaccgct
    30421 cgcactcagc caagttgcgc gtggccagaa aaattcacaa gtaagaggga aaaagatggc
    30481 agaaaaaatg gaaaaaacag gtcaaatact acagatgcaa cttaaacggt tttcgcgtgt
    30541 ggaaaaagct ttttactttt ccattgctgt aaccactctt attgtagcca ttagtattat
    30601 ttttatgcag accaagctct tgcaagtgca gaatgatttg acaaaaatca atgcgcagat
    30661 agaggaaaag aagaccgaat tggacgatgc caagcaagag gtcaatgaac tattacgtgc
    30721 agaacgtttg aaagaaattg ccaattcaca cgatttgcaa ttaaacaatg aaaatattag
    30781 aatagcggag taagatatga agtggacaaa aagagtaatc cgttatgcga ccaaaaatcg
    30841 gaaatcgccg gctgaaaaca gacgcagagt tggaaaaagt ctgagtttat tatctgtctt
    30901 tgtttttgcc atttttttag tcaattttgc ggtcattatt gggacaggca ctcgctttgg
    30961 aacagattta gcgaaggaag ctaagaaggt tcatcaaacc acccgtacag ttcctgccaa
    31021 acgtgggact atttatgacc gaaatggagt cccgattgct gaggatgcaa cctcctataa
    31081 tgtctatgcg gtcattgatg agaactataa gtcagcaacg ggtaagattc tttacgtaga
    31141 aaaaacacaa tttaacaagg ttgcagaggt ctttcataag tatctggaca tggaagaatc
    31201 ctatgtaaga gagcaactct cgcaacctaa tctcaagcaa gtttcctttg gagcaaaggg
    31261 aaatgggatt acctatgcca atatgatgtc tatcaaaaaa gaattggaag ctgcagaggt
    31321 caaggggatt gattttacaa ccagtcccaa tcgtagttac ccaaacggac aatttgcttc
    31381 tagttttatc ggtctagctc agctccatga aaatgaagat ggaagcaaga gcttgctggg
    31441 aacctctgga atggagagtt ccttgaacag tattcttgca gggacagacg gcattattac
    31501 ctatgaaaag gatcgtctgg gtaatattgt acccggaaca gaacaagttt cccaacgaac
    31561 gatggacggt aaggatgttt atacaaccat ttccagcccc ctccagtcct ttatggaaac
    31621 ccagatggat gcttttcaag agaaggtaaa aggaaagtac atgacagcga ctttggtcag
    31681 tgctaaaaca ggggaaattc tggcaacaac gcaacgaccg acctttgatg cagatacaaa
    31741 agaaggcatt acagaggact ttgtttggcg tgatatcctt taccaaagta actatgagcc
    31801 aggttccact atgaaagtga tgatgttggc tgctgctatt gataataata cctttccagg
    31861 aggagaagtc tttaatagta gtgagttaaa aattgcagat gccacgattc gagattggga
    31921 cgttaatgaa ggattgactg gtggcagaat gatgactttt tctcaaggtt ttgcacactc
    31981 aagtaacgtt gggatgactc tccttgagca aaagatggga gatgctacct ggcttgatta
    32041 tcttaatcgt tttaaatttg gagttccgac ccgtttcggt ttgacggatg agtatgctgg
    32101 tcagcttcct gcggataata ttgtcaacat tgcgcaaagc tcatttggac aagggatttc
    32161 agtgacccag acacaaatga ttcgtgcctt tacagctatt gctaatgacg gtgtcatgct
    32221 ggagcctaaa tttattagtg ccatttatga tccaaatgat caaactgctc ggaaatctca
    32281 aaaagaaatt gtgggaaatc ctgtttctaa agatgcagct agtctaactc ggactaacat
    32341 ggttttggta gggacggatc cggtttatgg aaccatgtat aaccacagca caggcaagcc
    32401 aactgtaact gttcctgggc aaaatgtagc cctcaagtct ggtacggctc agattgctga
    32461 cgagaaaaat ggtggttatc tagtcggggt aaccgactat attttctcgg ctgtatcgat
    32521 gagtccggct gaaaatcctg attttatctt gtatgtgacg gtccaacaac ctgaacatta
    32581 ttcaggtatt cagttgggag aatttgccaa tcctatcttg gagcgggctt cagctatgaa
    32641 agactctctc aatcttcaaa caacagctaa agctttggag caagtaagtc aacaaagtcc
    32701 ttatcctatg cctagtgtca aggatatttc acctggtgat ttagcagaag aattgcgtcg
    32761 caatcttgta caacccatcg ttgtgggaac aggaacgaag attaaaaaca gttctgctga
    32821 agaagggaag aatcttgccc cgaaccagca agtccttatc ttatctgata aagcagagga
    32881 agttccagat atgtatggtt ggacaaagga gactgctgag acctttgcta agtggctcaa
    32941 tatagaactt gaatttcaag gttcgggctc tactgtgcag aagcaagatg ttcgtgctaa
    33001 cacagctatc aaggacatta aaaaaattac attaacttta ggagactaat atgtttattt
    33061 ccatcagtgc tggaattgtg acatttttac taactttagt aggaattccg gcctttatcc
    33121 aattttatag aaaggcgcaa attacaggcc agcagatgca tgaagatgtc aaacagcatc
    33181 aggcaaaagc tgggactcct acaatgggag gtttggtttt cttgattact tctgttttgg
    33241 ttgctttctt tttcgcccta tttagtagcc aattcagcaa taatgtggga atgattttgt
    33301 tcatattagt cttgtatggc ttggtcggat ttttagatga ctttctcaag gtctttcgta
    33361 aaatcaatga ggggcttaat cctaagcaaa aattagctct tcagcttcta ggtggaatta
    33421 tcttctatct tttctatgag cgtgggggcg atatcctgtc tgtctttggt tatccagttc
    33481 atttgggatt tttctatatt ttcttcgctc ttttctggct agtcggtttt tcaaacgcag
    33541 taaacttgac agacggtgtt gacggtttag ctagtatttc cgttgtgatt agtttgtctg
    33601 cctatggagt tattgcctat gtgcaaggtc agatggatat tcttctagtg attcttgcca
    33661 tgattggtgg tttgctcggt ttcttcatct ttaaccataa gcctgccaag gtctttatgg
    33721 gtgatgtggg aagtttggcc ctaggtggga tgctggcagc tatctctatg gctctccacc
    33781 aagaatggac tctcttgatt atcggaattg tatatgtttt tgaaacaact tctgttatga
    33841 tgcaagtcag ttatttcaaa ctgacaggtg gtaaacgtat tttccgtatg acgcctgtac
    33901 atcaccattt tgagcttggg ggattgtctg gtaaaggaaa tccttggagc gagtggaagg
    33961 ttgacttctt cttttgggga gtgggacttc tagcaagtct cctgacccta gcaattttgt
    34021 atttaatgta agaatggcat cctgatgttt cagggtgttt ttgtatttaa atacacaatg
    34081 aaaatcaaag aacaaactag aaagctaact ttaggctgct caaa
//
LOCUS       DAVBNZ010000018        33505 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000018 DAVBNZ010000000
VERSION     DAVBNZ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33505
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.018"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            252..512
                     /locus_tag="VQ860_000907"
     CDS             252..512
                     /locus_tag="VQ860_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119357.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            466..686
                     /locus_tag="VQ860_000908"
                     /pseudo
     CDS             466..686
                     /locus_tag="VQ860_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1005..1934
                     /locus_tag="VQ860_000909"
     CDS             1005..1934
                     /locus_tag="VQ860_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3119358.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            1948..2871
                     /locus_tag="VQ860_000910"
     CDS             1948..2871
                     /locus_tag="VQ860_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3119359.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            2955..4430
                     /locus_tag="VQ860_000911"
     CDS             2955..4430
                     /locus_tag="VQ860_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET3119360.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            4702..5688
                     /locus_tag="VQ860_000912"
     CDS             4702..5688
                     /locus_tag="VQ860_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET3119361.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            5810..6670
                     /locus_tag="VQ860_000913"
     CDS             5810..6670
                     /locus_tag="VQ860_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET3119362.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(6847..7911)
                     /locus_tag="VQ860_000914"
     CDS             complement(6847..7911)
                     /locus_tag="VQ860_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119363.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(7974..8885)
                     /locus_tag="VQ860_000915"
     CDS             complement(7974..8885)
                     /locus_tag="VQ860_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET3119364.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILNQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(8878..9471)
                     /locus_tag="VQ860_000916"
     CDS             complement(8878..9471)
                     /locus_tag="VQ860_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET3119365.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            complement(9458..9784)
                     /locus_tag="VQ860_000917"
     CDS             complement(9458..9784)
                     /locus_tag="VQ860_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3119366.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            complement(9923..11089)
                     /locus_tag="VQ860_000918"
     CDS             complement(9923..11089)
                     /locus_tag="VQ860_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET3119367.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            11147..12286
                     /locus_tag="VQ860_000919"
     CDS             11147..12286
                     /locus_tag="VQ860_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3119368.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            12354..14204
                     /locus_tag="VQ860_000920"
     CDS             12354..14204
                     /locus_tag="VQ860_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3119369.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSAFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(14383..14481)
                     /locus_tag="VQ860_000921"
                     /pseudo
     CDS             complement(14383..14481)
                     /locus_tag="VQ860_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(14507..15139)
                     /locus_tag="VQ860_000922"
     CDS             complement(14507..15139)
                     /locus_tag="VQ860_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3119370.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(15161..16033)
                     /gene="sdaAA"
                     /locus_tag="VQ860_000923"
     CDS             complement(15161..16033)
                     /gene="sdaAA"
                     /locus_tag="VQ860_000923"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET3119371.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(16042..16713)
                     /gene="sdaAB"
                     /locus_tag="VQ860_000924"
     CDS             complement(16042..16713)
                     /gene="sdaAB"
                     /locus_tag="VQ860_000924"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET3119372.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            16955..17527
                     /locus_tag="VQ860_000925"
     CDS             16955..17527
                     /locus_tag="VQ860_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3119373.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(17579..17899)
                     /locus_tag="VQ860_000926"
     CDS             complement(17579..17899)
                     /locus_tag="VQ860_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3119374.1"
                     /translation="MQRLEVYKNYQHLYDLQIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            18324..18608
                     /locus_tag="VQ860_000927"
     CDS             18324..18608
                     /locus_tag="VQ860_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3119375.1"
                     /translation="MRKLVKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSGNFG
                     YSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            18663..20771
                     /locus_tag="VQ860_000928"
     CDS             18663..20771
                     /locus_tag="VQ860_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3119376.1"
                     /translation="MKKISHLCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     VLASRMEKRSLVELLKGGIL"
     gene            20768..21409
                     /locus_tag="VQ860_000929"
     CDS             20768..21409
                     /locus_tag="VQ860_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119377.1"
                     /translation="MIELENITKTIGGKVILDHLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSSTLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            21616..22422
                     /locus_tag="VQ860_000930"
     CDS             21616..22422
                     /locus_tag="VQ860_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3119378.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            22388..22858
                     /locus_tag="VQ860_000931"
     CDS             22388..22858
                     /locus_tag="VQ860_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HET3119379.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYIIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(23148..23468)
                     /locus_tag="VQ860_000932"
     CDS             complement(23148..23468)
                     /locus_tag="VQ860_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3119380.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKFIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            24232..24612
                     /locus_tag="VQ860_000933"
     CDS             24232..24612
                     /locus_tag="VQ860_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HET3119381.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            24986..26044
                     /locus_tag="VQ860_000934"
     CDS             24986..26044
                     /locus_tag="VQ860_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119382.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILIFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKR"
     gene            26359..27335
                     /locus_tag="VQ860_000935"
                     /pseudo
     CDS             26359..27335
                     /locus_tag="VQ860_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            27712..28086
                     /locus_tag="VQ860_000936"
     CDS             27712..28086
                     /locus_tag="VQ860_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET3119383.1"
                     /translation="MELVLPNNYVALEQEEMMYFDGGFSIPRWPVATAINIAFNDVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGN
                     AITTIWANNDVNRRDPNLNALW"
     gene            28294..29196
                     /locus_tag="VQ860_000937"
     CDS             28294..29196
                     /locus_tag="VQ860_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119384.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            29252..29605
                     /locus_tag="VQ860_000938"
     CDS             29252..29605
                     /locus_tag="VQ860_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET3119385.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGEAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYYIGYGVLNRGCDIN
                     GNPYPWDGFISATVK"
     gene            29602..30330
                     /locus_tag="VQ860_000939"
     CDS             29602..30330
                     /locus_tag="VQ860_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119386.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            31462..31701
                     /locus_tag="VQ860_000940"
     CDS             31462..31701
                     /locus_tag="VQ860_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119387.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     DLHKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            32251..>33505
                     /locus_tag="VQ860_000941"
     CDS             32251..>33505
                     /locus_tag="VQ860_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET3119388.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVASQSKAEK
                     DYDAAKRDAENAKKALEEAKRAQKKYEDDQKKTEEKAKKEKEASKEEQAANLKYQQEL
                     VKYASEKDSVKKAKILKEVEEAEKEHKKKRAEFEKVRSEVIPSAEELKKTRQKAEEAK
                     AKEAELIKKVEEAEKKVTEAKQKLDAERAKEVALQAKIAELENEVYRLETELKGIDES
                     DSEDYVKEGLRAPLQSELDAKRTKLSTLEELSDKIDELDAEIAKLEKNVEYFKKTDAE
                     QTEQYLAAAEKDLADKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPAPAPKPEKTDDQQAEEDYARRSEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAP
                     KTGWKQENGMWYFYNTDGSMATGWLQ"
BASE COUNT        10513 a         5570 c         6958 g        10464 t
ORIGIN      
        1 cacatctact tctaaaacat tgttagaaat cgatttgact gtcctgatcg atttgtcctg
       61 ttcttgtttc attttactat agaacgattt gaaggcgttt atgatattta gctgtacgag
      121 agtcttttaa aagtgttttg atagtttgga tttcttcttt agttgatttc atatcactgt
      181 tatataatgc tttttgattt tagtctagta ttagtaagca gactcaaacc ttagaaaatc
      241 ttttgagatc attgacaggt gtatcgaatc ctaccacaga ttcagcacgt ctggttttgg
      301 cagaggctaa gaaagctttt gcagatgata gtttgacaga gcaaggttta cgtgatattt
      361 tgcaaacagt caaagatgcc attgcttccc tagagtccat taaggaaagc cagtcagcaa
      421 ctaaggatgg aggacaaaca gcgggcaaag aaacagcagg agaagatgag tctgcaaatc
      481 aaactcaaga aattagccaa ggaattaagt aaacttctta aagactcaaa ccttgaaaca
      541 gtagataagg atgtccttga aaactctcaa aaagaacttc aaaaagcagt tttgttcttg
      601 gcagatgaaa aagctctgag catactgaag cagaggtgat tgataatctt aaagaggtta
      661 ttgctaagtt gaaagcaaac gcctaataac atattaaaaa tctccagatt aggaactatc
      721 tctgagttcc ctagtctgga gatttttcag tataccccgt tgttggatgc ttataacaga
      781 gtgacgccat cactgggcta atagagataa aataaacaat tgatttagga catttgtttg
      841 atagtggtga taaagtttta aatctgctac ataatttgtg gagttttttc tataattagg
      901 agtttaacct aacctgcaaa taggagtata ctaataatgt aatcgttatc aaaagtctaa
      961 aaaagaattt ttagatggat atcaaaataa aaagggagga aattatgaaa aagttttcaa
     1021 aaacattgag agacaactgg atctttctct tgatggtttt gccagggaca ctctggttga
     1081 ttctattctt ttacattcca gtatttggga acgtggttgc cttcaaagac taccacatga
     1141 ccagtaatgg tttcatagat agtatcataa atagtaaatg ggtcggactc gataatttca
     1201 gattcttatt tagttcaaga gacgccttta ttatcacacg aaatactgtc ctctacaatc
     1261 ttggctttat ctttctaggt ttagttgtat ctgtagggat tgccattatc ctcagcgagc
     1321 tccgttctaa gagaatggtg aagattttcc aaacttctat gttgttccct tacttcttgt
     1381 cttgggttat catcagtttc tttacagatg ccttcctaaa tattgataaa ggggtgttca
     1441 atcatctatt ggaaagtctt ggtctcaaag aagtcaattt ttacgctgac ctgggcatct
     1501 ggccctatct cctacttttc ctaggtattt ggaaaggctt tggatatagc agtgtcatgt
     1561 actatgcgac gatcatggga attgatccaa cctactacga agcagcgaca gtggacggag
     1621 ctagcaagtg gcaacgtatt cgcaacgtaa ccattcctca gttgactccg cttgtaactg
     1681 tattgaccat ccttgcagtc ggaaatatct tccgcgcaga ctttggtctc ttctatcaaa
     1741 tcccacacaa tgctggtcag ctttacaatg taaccaacgt tttggacgta tatgtcttta
     1801 atggtttgac tcagacagca gatatcggta tggctgcagc agccggtctt taccaatccg
     1861 ttgttggttt gattctggtt atcctatcaa acttgcttgc aagacgagtc gatccaaact
     1921 cagctttgtt ctagaaagga ggagaatatg gcaaaaaaga aaattaaaaa agaaaaaatt
     1981 gataatgtcg gcattcactc cttcagtaag aaagcagata tcttcttcag tatcatttcg
     2041 ggtttgattg ccctctcttg tatcctacct tttgtattcg ttatcattat ttcagtgaca
     2101 gacgagaaaa gcctcctcca atacggctat agcttcttcc catcccaatt tggcttagac
     2161 ggttttgagt ttttggcaca gtttaaggat aaaatcctac aagccctctt catctctgtc
     2221 tttgtaaccg tagttgggac attgacaaat gtctttatca caacaaccta tgcctacgct
     2281 atttcacgga caacctttaa gtatcgcaga ttttttacca tcttcgtcct tctcagtatg
     2341 ttgttcaacg ctggtttggt accaggttat atcatggtga cccgtgtact tcagcttggt
     2401 gacactgttt gggccttgat tgttccaatg cttctctcac cattcaatat catcttgatg
     2461 cgttccttct tcaagaagac cattccagaa gccattctcg aatcggctcg tatcgatggt
     2521 gccagtgagg cccggatttt cttccaaatc tgtttgccat tgtcactacc aggtatcgca
     2581 accatcacgc ttttgacagc tcttggtttc tggaatgact ggttcaacgc ccttctttac
     2641 atcaagagtg ataacttgta tccattgcaa tatttgctca tgcaaatcca acaaaatatg
     2701 gactacattg ccaaagcggt cggcttgact ggtcaactgg gagttgctct accgaaagaa
     2761 acaggtcgta tggccatggt tgtggtagca acccttccaa tcgcgatttt gtatccattc
     2821 ttccaacgct actttgtaaa aggtttgact atcggtggtg tgaaagaata gcacttgttt
     2881 ccaaacttcc cttgcgtgaa gttaagatca ttacattgtt tataagttta aaaataaaaa
     2941 aaggagtttt tatcatgaaa aactggaaaa aatatgcttt tgcatctgct agtgtagttg
     3001 ctttggctgc aggtcttgct gcttgtggca acttgacagg taacagcaaa aaagctgctg
     3061 attcaggtga caaacctgtt atcaaaatgt accaaatcgg tgacaaacca gataacttgg
     3121 atgaattgtt agcaaatgcc aacaaaatca tcgaagaaaa agttggtgct aaattggata
     3181 tccaatacct tggctggggt gactatggta agaaaatgtc agttatcaca tcatctggtg
     3241 aaaactatga tatcgccttt gcagataact atattgtaaa tgctcaaaaa ggtgcttatg
     3301 ctgacttgac agaattgtac aaaaaagaag gtaaagacct ttacaaggca cttgatccag
     3361 cttatatcaa gggtaatact gtaaatggta agatttacgc tgtaccagtt gcagccaacg
     3421 tagcatcatc tcaaaacttt gccttcaacg gaactctcct tgccaaatat ggtatcgata
     3481 tttcaggtgt tacttcttac gaaactcttg agccagtctt gaaacaaatc aaagaaaaag
     3541 ctccagacgt agtaccattt gctattggta aagttttcat cccatctgat aactttgact
     3601 acccagtagc aaacggtctt ccattcgtta ttgaccttga aggcgatact actaaagttg
     3661 taaaccgtta cgaagtacct cgtttcaaag aacacttgaa gactcttcac aaattctatg
     3721 aagctggcta cattccaaaa gacgtcgcaa caagcgatac ttcctttgac cttcaacaag
     3781 atacttggtt cgttcgtgaa gaaacagtag gaccagctga ctacggtaac agcttgcttt
     3841 cacgtgttgc caacaaagat atccaaatca aaccaattac taacttcatc aagaaaaacc
     3901 aaacaacaca agttgctaac tttgtcatct caaacaactc taagaacaaa gaaaaatcaa
     3961 tggaaatctt gaacctcttg aatacgaatc cagaactctt gaacggtctt gtttacggtc
     4021 cagaaggcaa gaactgggaa aaaattgaag gtaaagaaaa ccgtgttcgc gttcttgatg
     4081 gctacaaagg aaacactcac atgggtggat ggaacactgg taacaactgg atcctttaca
     4141 tcaacgaaaa cgttacagac caacaaatcg aaaattctaa gaaagaattg gcagaagcta
     4201 aagaatctcc agcgcttgga tttatcttca atactgacaa tgtgaaatct gaaatctcag
     4261 ctattgctaa cacaatgcaa caatttgata cagctatcaa cactggtact gtagacccag
     4321 ataaagcgat tccagaattg atggaaaaat tgaaatctga aggtgcctac gaaaaagtat
     4381 tgaacgaaat gcaaaaacaa tacgatgaat tcttgaaaaa caaaaaataa tcagctaaat
     4441 tgatttcgtg tattcattcc taactcctaa aataagaatc actgctttcc tcaggttggt
     4501 ctgggggaga cagtggtttt tttggcacaa ggatatagat atccatgttt tctcttgtcc
     4561 ttattttaac cattcaggaa atttcgagaa ccctctacaa tttccagtca aataaattgc
     4621 attcgttttc tcaagcaggt atactagtgt agataaataa aaaatttaga aaatttaaga
     4681 atagaaaaga gaacaaatct tatggcaaaa gatattcgtg tcttacttta ctacctttat
     4741 actccaattg aaaatgcaga gcaatttgct gcagaccact tggctttctg taaatcaatc
     4801 ggtcttaaag gccgtatcct agtcgctgac gagggaatta acggaacagt ttcaggtgac
     4861 tatgaaacaa ctcaaaaata catggactac gttcacagcc ttccaggaat ggaagaactc
     4921 tggttcaaga ttgacgaaga aagtgaacaa gccttcaaga agatgtttgt tcgctacaag
     4981 aaagaaattg tccaccttgg tttggaagac aacgactttg acaatgacat caacccactt
     5041 gaaacaacag gtgcttactt gtctccaaaa gagttcaaag aagcgcttct tgataaagat
     5101 accgttgtcc ttgacacacg taatgattat gagtatgacc taggacattt ccgtggggct
     5161 attcgcccag atattcgcaa cttccgtgag ttaccacaat gggtccgtga taacaaggaa
     5221 aaattcatgg acaagcgtgt cgtggtttac tgtacaggtg gcgttcgctg tgagaaattc
     5281 tcaggctgga tggttcgtga aggttacaaa gatgtcggcc aattgcacgg aggaatcgca
     5341 acttacggta aagacccaga agttcaaggt gagctttggg atgggaaaat gtacgtcttt
     5401 gacgagcgta ttgccgttga tgtcaaccat gtcaacccaa ctatcgtagg gaaagactgg
     5461 tttgatggaa caccatgtga acgttatgtc aactgtggaa atccattctg taaccgtcgt
     5521 atcttgacat cagaagaaaa tgaagacaag taccttcgtg gatgctcaca cgagtgccgt
     5581 gttcacccac gtaaccgcta tgtttcaaaa aatgaattga cacaagctga agtgattgag
     5641 cgcctagccg ctatcggtga aagcttggat caagcagcta ctgtataaga tcaaacagtc
     5701 ctcaggggct gtttttctat gctttgtact caaaaatcta aagtttgttt ctgtatcttt
     5761 cagaaaaata aggtatactg tatgtaaacg atttcaaagg agtccagtta tggcaaaaac
     5821 attttttatt ccaaataaac agagcatttt aggagaacaa gagattttga atgccaagtc
     5881 gatcttggcc ttgctagacg gtttggagtc acatagctat gatgtagtct atctccgtca
     5941 gcctcttaat cgtctcgagt atattgagtg tgcgatagtg gggcaatcac aatttctttt
     6001 taaggtcagt tatgctgatg gtcaaaaggc ttaccgtgtc gatcttcctg acctactaac
     6061 aaagacagac tggcagatta tcaagtcatt tttagatgct ttgcttgctt atacagggac
     6121 tgatattgaa gggctagatg gttttgattt tgaagcttat ttccaagcaa gtattcaagc
     6181 ctatctagca gaccctgtag ctcgttttac gatttgccaa ggaattttta atcctatttt
     6241 ctttagtcgt gagaacttga aaagcttttt agaggcagat ggcttggctc agtttgaagc
     6301 gcgtgtgcgt gcggttcaag agacagatgc ctactttgcg agagtttcct tctatcagga
     6361 tggagaagga aaagtgcatg gcgtttacca tctagctcaa ggagtcaaga cagttttacc
     6421 gagagaaccg tttgttcctg cagcctatat tgagcaattg gtggataagg aagtgcagtg
     6481 ggagattgac ttggttcaaa tcacaggaga tggctctaaa ccagaagact atgaagccat
     6541 tgcccgcttg gactatgcaa aattcttaga ggtattaccc ctatcttttt accaccaact
     6601 agacgccaat caaatagaag tgcaacccat attagacaaa gattttaaag cattagcaca
     6661 agaagagtaa agcagaagca ggtcaatcga cttgcttttt tgaaatagaa aaatcctgcc
     6721 atgaaagaca ggattgctac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag
     6781 gctgtacttg agtacggtaa ggcgaagctg acgtggtttg aatttgattt tcgaagagta
     6841 tgaagtttaa agaaaggcca agatacgaag ataatctcca atcagtgcca cttcagctac
     6901 aaagaagagg aggataataa ctccgttcac aaggacagac aagaataatt gatagaagga
     6961 gtcggtttca cttgcttgac ttggtcttgt aatgatatgg agactggcaa gcagaatgat
     7021 tccaatgcta atcacacaca agagggctgt aaatcgtagg ctatcaaaga aagcaaagaa
     7081 actagcaata gcagtgagga agattggaat tgctaagagt tgactatatt gttggagaac
     7141 cttgtctagc gtccagtcct tttcctggtg gataaatcgt ctcacaacga aactacccaa
     7201 gaggaatgaa aagaagaaga gtgttgtcgc tactaggata gagatgatag aaaaaagagt
     7261 taaaggagct agctgctcag ggaagcgact gttaatgctt gctatatgtc catagtaagc
     7321 atgtttgatg tgatagatac taaagaaaaa ggaagatgca gaaaacagaa tgagcaagag
     7381 aaaggctgtg taactgtgtg tgatacttgt ttccaactta cttgtaggag atttgatcgc
     7441 ttccactagc caagaccaaa aatcaagcac ttgctctttc catttatccc tagattttgg
     7501 agcttggtcg gggatataag gactttctaa agatttactg ataagaagtg gctctttcgt
     7561 ggttgctttt tgctgaggaa gagcttcttg gctctcttca gctatagtga ctttttctgt
     7621 ttctttagaa aggtctggct cttcttcagt agaattagat gccttctttt cttctatttc
     7681 tgttctcgct tcactgtctt caggagcttc aattttctct tcttgctggc tttccaattc
     7741 gacttcagct tgagggactt cctcctctaa ctgagtattt ttttcaattg gtgtatcgag
     7801 atcggctatc gtttcttcag ccttgtctgc aacctcttga gcttgctctt caggcttgtt
     7861 cttgcttgtt gtttttacaa aatcattact ttcaaaccat tcttgtttca tggtagaacc
     7921 tcctttttag ttagataaat atgcttccat agtagcagat gtaagcgttt ttgtcaacgt
     7981 ctgcttggtg tggatattag atcaatatta tcatcagatc tcgcaatgag ttgatccttg
     8041 acatcggttt tttcagtttt gtaagggttg cttaattccg tacctcttga ttcaggcttt
     8101 tctcttgtga attggaagat agaaccatag ttgcttgaga tgtcccagtt aattcgttgg
     8161 ctttctttct ggtttaggat gattctgaga taatctttgg cagtcagttc aaccttgcca
     8221 tggacttgga tattttcagc gtggaagtga ttctctgttg actctagctg actatctgta
     8281 agaactgtat caaagatatt aacgatattg ggcgttgtga gtttactgtt tttgatacga
     8341 cttccttcaa ttcggaggat atagctgttt gtattgaggg tcgcattttc aaggctagca
     8401 tttatgatgg tggtttgtcc gcgattggct gagatgttga tcccttttag agttctccct
     8461 tttggtagct ggagaataac ttcttcaaaa cgactagagt agctacttgc gatatgaaga
     8521 atcccaccaa ttccagaaga gagaaacgga gtttcagaca gtttcttatc agtgagactc
     8581 agagttctat cgttctgatt ggtgataaga tcatggtgag cagaaagaga tggatggtaa
     8641 gaaatgtgga tttgatcatc gaaagagtct gtgatggtga gcgcgtgttg gtggagagta
     8701 atttctaggt tttcgacttc cttgccaaag gttagctttt ccgtacggct atcatagata
     8761 ggttctttgg acatggaaag taggctttta atcccgtcag attggatacc tacaaaaaga
     8821 aggataaagc cgataacggt agtcaccaca ccaaagatga gaaatccttt tgtccattta
     8881 cgcatgctgg ttacctctct ttcttttttt aagaacaaat tgtaccaggc gaacaatgag
     8941 tagaccgaag aagcgagcta cataggaaat gcctagtaaa actagcgaag aagcaccgat
     9001 agccagtaaa ccagaaccaa aaatcaagat aaaggctgat ttggcttggg cgaggacagt
     9061 gaaactttca actaaaaata ggaatccgcc gatgataccc agtatggaaa ctgcaaagaa
     9121 agccagaatg acagtcaaag cggctacaag gattgcgaac agggtcacga ggatggcgat
     9181 tcccagagga atgccgatag gtgctgcaag gagggctaac aaggcgatat gtaaaatttg
     9241 tcggttattt ttttgagcgg gtgcttcatt gattttttta tcgagaagat tggatagaac
     9301 ttcgtgggcc gcttctttgg gagttcccaa actagcgatg agttcttctt ctccttcgac
     9361 tccagcatcg tcaaagagct ctctgaaata gtccatggct tcgatacggt cagcttcagg
     9421 tagtttcttg agatagagtt ctagctgagt caggtattca gttcttgtca tggcggatac
     9481 tcccttctat gatgccattg atggtgtctg tatagagtgc ccattcatct tttagggtca
     9541 agagctgctc tataccaccg tttgtcaagg agtagtattt gcgcatgcga ccttggaact
     9601 ctctagaata ggttgtcaga aagctattgc cttccaattt tttgagaatg ggatagagtg
     9661 tggattcttt gatattagcg atcagcttaa tggtttggct aatctcataa ccataagaat
     9721 caccctgctc cagtacggcc aagatgagaa attcaatcaa ggcagaggat gttggaaagt
     9781 acatgggaaa cctccttttc taatgtgtaa gatttttata tataattttt ctacacatac
     9841 attgtacatc taaaagaaag ccctgtcaag agaaatgtgt aaaattttta tatataaaaa
     9901 acttctagct aaaactagaa gtttaaagga tcttatccgc tctgtccact gtaaagaggg
     9961 ccacagtcat caggatatcg atgagcaaga gggcagctac agctggtacc caagagtgga
    10021 ataggtcaaa actgtaacca aagagggttg gcccaaaggc tgctaggata tagcctcctg
    10081 tttgagatag gccggacaat tgggctgtct tttcaggggc gcttgtcttg agtgaaaagt
    10141 tgaccatgag ataagggaag agggcgctgg ttgcggttcc gatgaggaga tggatggcaa
    10201 gccagtaaat gaaattattg attgggaaaa agagcatgga aatgccgacc acaccagcta
    10261 gtgaaaccag agtgagcatg agctgacggt tgcgagtaga taaactggtt gtcaggcttg
    10321 ggatggtcat tgaaaaagga atgctaatca gagataagat agaagtcagc aagccagctt
    10381 cgtgactgga tagacctgca tggatagaca tggtaggtaa ccaggtcatg gcggtgtaaa
    10441 agatcaagga ttgaaaacct gaaaagataa taattgccca aacctgttta ttacgcatga
    10501 cctttatttg acttttttgt ttggtttgtg gagctagtct atgattatag cggtgatttg
    10561 ggagccagac caaaaaagtt gctagacaga gtaacgtgag gaggaggata agtcctttcc
    10621 aagaactggc ttgtgtaatg ggcacagcta gataggaagc cagagccgtt gcaatcccca
    10681 tagacgttac atataaggtg gtcagaaaac caattttctt tggttgattg gcttggataa
    10741 gactaggaag caggacattg atgactgcga cacttgcccc aaccatcaag gttcctagat
    10801 agagcagggg cagattgatt agtcgaataa gtgagccgat ggtcaagaag aagaggctgt
    10861 aggtgaagag atgctccaag ccgattttct gagccagtcg ggtagaaaat ggtgaaaaga
    10921 gggtaaacat aaggagaggc aggctggtca agacaccaag cgaactaact tctacctcca
    10981 gaccttgcga aatatttccc aaaataatgg gtaaaacagt aaaaggagtt cgcaaggaaa
    11041 caccaatcag gataatacct ggaacaaaaa agagtgattg ctttttcata taatatctct
    11101 tctagctgat tttaataaca gcttatttta aggctttttc actataatgt caagtaaggt
    11161 ttctggcttt caagataaaa atggaaaagt cttgaaaatt atgatagaat ggtggaaggg
    11221 aaaattcagg agagtagtag tgactcaaaa tgttgaaagt cttctcgtat ccattgtaat
    11281 cagtgcatac aatgaagaaa aatatctgcc tggtctaatt gaagacttaa aaaatcaaac
    11341 ctatcctaaa gagaatattg aaattctatt tataaatgct atgtccacag atgggaccac
    11401 agctatcatt cagcaattta taaaagaaga tgcagagttt aactcaatta gattgtataa
    11461 caatcctaag aaaaatcaag ctagtggttt taacctggga gttaagcatt ctgtaggggg
    11521 ccttatttta aaaattgatg ctcattcaaa agttactgag agttttgtaa tgaacaatgt
    11581 ggctgttatt caacaaggtg aatttgtctg tggagggcct agaccgacga ttgtcaaagg
    11641 aaaaggaaaa tgggcagaga ccttgcatct tgttgaggaa aatatgtttg gcagtagcat
    11701 tgccaattat cgaaatagtt ccgaggatag atatgtttct tctatttttc atgggatgta
    11761 taaacgagag gttttccaga aggttggttt agtaaatgag caacttggcc gaactgaaga
    11821 taatgatatt cattatagaa ttcgagaaca tggttataaa atccgctata gcccaagtat
    11881 tctatcttat cagtatattc gaccaacatt caagaaaatg ctgcatcaaa agtattcaaa
    11941 tggtttgtgg attggcttga caagtcatgt tcagtttaag tgtttatcat tatttcatta
    12001 tgttccttgt ttatttgttt tgagtcttgt gtttagtcta gcattgttac cgatcacatt
    12061 cgtattcata actttactat taggtgccta ttttctactt ttatcattac tgtcattact
    12121 cactttgctg actttattaa aacataaaaa tggatttcta attgtgatgc cctttctttt
    12181 attttccatt cactttgctt atggccttgg gacgattgta ggtttaatta gaggatttaa
    12241 atggaagaag gagtacaagg gaacagtaat ttatttggaa aaataagcca aataaattaa
    12301 aatgtgctat aataacaata tagtagaact attttaagga ggagtaaatt tctatgaata
    12361 aaaaactcac agattatgtg attgatctgg tggaaatttt aaataaacaa caaaagcagg
    12421 ttttctgggg aatatttgat attttcagta tggtggtttc catcattgta tcttatattt
    12481 tattttatgg gctgattaat ccagcacctg ttgactacat tatctatacg agtttggcct
    12541 tcctgttcta tcaattgatg gttgattttt ggggcttgag cgcgagtatt agtcgttaca
    12601 gcaagattac ggatttcatg aaaatctttt ttggtgtgac tgctagcagt gtcttgtcat
    12661 atagtatctg ttatgccttc ttgccactct tctccatccg ttttatcatt ctctttatct
    12721 tgttgagtgc cttcttgatt ttattgccac ggattacttg gcagttaatc tactccagac
    12781 gcaaaaaagg tagtggtgat ggagaacacc gtcggacctt cttgattggt gccggtgatg
    12841 gtggggctct ctttatggat agttaccaac atccaaccag tgaattagaa ctggtcggta
    12901 ttttggataa ggattctaag aaaaagggtc aaaaacttgg tggtattcct gttttgggct
    12961 cttatgacaa tctgcctgaa ttagccaaac gccatcaaat cgagcgtgtc atcgttgcga
    13021 ttccgtcgct ggatccgtca gaatatgagc gtatcttgca gatgtgtaat aagctgggtg
    13081 tcaaatgtta caagatgcct aaggttgaaa ctgttgttca gggccttcac caagcaggta
    13141 ctggcttcca aaaaattgat attacggacc ttttgggtcg tcaggaaatc cgtcttgacg
    13201 aatcgcgtct gggtgcagaa ctgacaggta agaccatctt agtcacagga gctggaggtt
    13261 caatcggttc tgaaatctgt cgtcaagtta gtcgcttcaa tcctgaacgc attgtcttgc
    13321 tcggtcatgg ggaaaactca atctaccttg tttatcatga attgattcgt aagttccaag
    13381 ggattgatta tgtacctgtg attgcggaca ttcaagacta tgatcgtttg ttgcaagtct
    13441 ttgagcagta caaacctgct attgtttatc atgcggcagc ccacaagcat gttcctatga
    13501 tggagcgcaa tccaaaagaa gccttcaaaa acaatatccg tggaacttac aatgttgcta
    13561 gagccgttga tgaagccaag gtgcctaaga tggttatgat ttcgacagat aaggcagtca
    13621 atccaccaaa tgttatggga gcaaccaagc gcgtggcgga gttgattgtc actggcttta
    13681 accaacgtag ccaatcaacc tactgtgcag ttcgttttgg gaatgttctt ggtagccgtg
    13741 gtagtgtcat tccagtcttt gaacgtcaga ttgctgaagg tgggcctgta acggtgacag
    13801 acttccgcat gacccgttac tttatgacca ttccagaagc tagccgtctg gttatccatg
    13861 ctggtgctta tgccaaagat ggggaagtct ttatccttga tatgggcaaa ccagtcaaga
    13921 tttatgactt ggccaagaag atggtgcttc taagtggcca cactgaaagt gaaattccaa
    13981 tcgttgaagt tggaatccgc ccaggtgaaa aactctacga agaactcttg gtatcaaccg
    14041 aactcgttga taatcaagtt atggataaga ttttcgttgg taaggttaat gtcatgcctt
    14101 tagaatccat caatcaaaag attggagagt tccgcactct cagtggagat gagttgaagc
    14161 aagctattat cgcctttgct aatcaaacaa cccacattga ataaaaaaga aaaacgcata
    14221 ttatcaagtt aaataacctt ggtaatatgc gttttattat gtagagactt atactcttcg
    14281 aaaatctctt caaatcacgt caacgtcgcc ttgccgtata tggttactga cttcgtcagt
    14341 tctatccaca acctcaaaac agtgttttga gctgacttcg tcagttccat ctacaacctt
    14401 aaaacagtgt tttgagcagc ccgcagctag tttcctagtt tgctctttga ttttcattga
    14461 gtattacttc attttcttct gaaatagagt tgtcgcccag tctatgctat tgaaaatacg
    14521 ccaaaacttc taagggtttg tgagcgatat aatcaggttg atagtttagt agatctgctt
    14581 gctctccaaa tccccaagtg acggccaatt tctgaatacc tgtttctcga gctcccagca
    14641 tatcaaactt ggtatctccg atgatgatgg cttgttctgg tgctagttga tgtgtctgta
    14701 aggcttggtg aatgacatct gccttatggg gtgcttcagg gctagaacca taaataccat
    14761 caaagaaatg atggatttcc aagtttttgg ccatgtcttg agcagtagat gtattctttg
    14821 tcgtggtgat gtagagtgga taactgctcg ataactcctc aagcaagtct ataatctgag
    14881 gaaagagttg agcttcatag atgccttttg ccttatagta agaacgatat atctgcatgg
    14941 cttcagaaat ttggtctttg gacaggcagg tcgcaaaact actttcgaga ggtggtccca
    15001 taaaaccacg aatagttttg gcatcagggc taggcacccc cagctcttta aaagtatagg
    15061 taaaggcatt gtgaatcccg atagaactat caacgagggt tccatccaaa tcgaaaaaaa
    15121 tcgctgtgat agaggtcatg gtttctccta tttgataagc ttattctccg aaaatctctt
    15181 tttggaggcg acgaccagta ggggtggtag cgagtccacc ttcagctgtt tcacgaaagg
    15241 cagttggcat gcttgctcct acttggtaca tggcatcgat cacttcatcc acagggattt
    15301 tagattcgat acctgccaag gccatgtctg ctgcgatgaa agcaaagcta gctcccatgg
    15361 cattacgttt gacacaggga acttcgacca aacctgcaac agggtcacag atgaggccta
    15421 gcatattttt aatgacaaag gcaatagctt gactggcctg ataaggtgtt ccacctgcag
    15481 ccagagtcaa ggcggcagca ctcatagcag aggctgaacc aacttcagct tgacacccac
    15541 cctcagcacc tgagatggag gcattgtttg cgatgactag tccaaaggca ccagcagcaa
    15601 agaggaaatc caattgttgc tcgtggctga ggtctaattt ttcaatagca gcagtgagaa
    15661 cggaagggag acaaccggca cttcctgcgg taggagtagc gcagaccaag cccattttag
    15721 cattgtgttc attgactgcg atagcatttc gggcagcaga gagaatcgtg taatctgata
    15781 aagttttttc gtttttgatg tagtgatcca atttggcagc atctccacct gtcaggccac
    15841 tacgagattt attttcattg aggccaagtt ggacagaggc tttcataact tccagattgc
    15901 gttccatgag aaggaagact tcttcacgtt cgcgaccggt caattcaaac tctgttgtaa
    15961 tcatgagttc tgcgacattt ccttgaaagt ccagatctgc ttgctcgacc aattctttga
    16021 tagaataaaa catgcttcct cctatttaaa gaaattgaca ttgtggagat gagggatttt
    16081 tcgaatttct tcgatagcct catcacagtt gcgactgtca acttcgataa tcataatggc
    16141 tttttcacca gctttttcac gagtgacatt catctgggcg atattgatac catagcggga
    16201 aagcgcctct gtaacaaggg caatcatacc tggaatatct tgatgaacga tgatgatagt
    16261 cggtgtattc atattgagag agacggcaaa accattgagt tcggttacct gaatatttcc
    16321 tccaccgata gaaataccag tcacgctgat ggtcttgtgg gcatttttaa cagtaatttt
    16381 agtggtgtta gggtgagggg cattgctgtc tttctgaatg gtccagacaa tcttgatacc
    16441 acgcttgtgg gcaatttcca gactatttgg aatttcagga tcatctgtat ccattcctaa
    16501 aatacctgca acaagggcta ggtctgttcc gtgaccacga taggtcttgg caaatgagtt
    16561 aaaaagttgg aattcaactt ctgtcggagt atcatcaaaa atggaagaga caatcttccc
    16621 aatacgaaca gcaccagcgg tatggctact agatgggcca atcataactg gtccgatgat
    16681 atcaaagaca gattgaaaac gaagtgattt catcagtttc cccttataaa aattcttatc
    16741 tctattatat caaagaatga ggggcttggc tttaattgtg gatgaaaacc tttctaatac
    16801 ctcaaatagc ataaaaatag tatcttttat gacaaaaaac accttattta gggaaataaa
    16861 aaataatttt gtaatatttc tacataaaag tgtcaagaaa cggtaatatt taaagggtat
    16921 gatagaacta tagaaagaag gagaattttc gaatatgaaa tcaataacta aaaagattaa
    16981 agcaactctt gcaggagtag ctgccttgtt tgcagtattt tctccatcat ttgtatctgc
    17041 tcaagaatca tcaacttaca ctgttaaaga aggtgataca ctttcagaaa tcgctgaaac
    17101 tcacaacaca acagttgaaa aattggcaga aaacaaccac attgataaca ttcatttgat
    17161 ttatgttgat caagagttgg ttatcgatgg ccctgtagcg cctgttgcaa caccagcgcc
    17221 agctacttat gcggcaccag ccgctcaaga tgaaactgtt tcagctccag tagtaagtga
    17281 aacagttgtt tcaactgtaa gcggatctga agcagaagcc aaagaatgga tcgctcaaaa
    17341 agaatcaggt ggtagctata cagctacaaa tggacgttat atcggacgtt accaattaac
    17401 agattcatac ctgaacggtg actactcagc tgaaaaccaa gaacgtgtag cagatgccta
    17461 cgttgcagga cgttacggtt catggactgc tgctaaaaac ttctggctta acaatggctg
    17521 gtattaagaa ctaacgaaca aataatatgt aaagagtcga ggaaatccct cggctttttt
    17581 atctttcctt cgcttggtaa tagatctcta cttctttttt gagatgagac agcatagaag
    17641 tttcctcggt tagctccaga agggagaacc ctttttggat aagtttagaa tcgtctgtac
    17701 aaatcccaat acggacatag cagatagcca gcctatcgta gcttttctta ttcttggcgt
    17761 cctctagtaa agtgtagcag atttgcttac acatgttttt atcttgattg tatagataga
    17821 gtgtggaaag gttgagcagg attgctattt gcaagtcata taaatgttga tagtttttat
    17881 agacttctaa gcgttgcaag attttctcgg attattgaca aataaacgga cattctgata
    17941 gacgattgcc ctagcggctt agtgtaaact ttacaaattt ggcttgtaat ttttttataa
    18001 aattcacttc agttacttga cagttattat attttcactt attatataga taaaaggatg
    18061 agatgggagt ttaaaaattt gaaagcgcta tccatattgt ttattggact gattcttgag
    18121 taatagttag agtgtgctta atactactct ggttgttcaa ggacctgata cagaagcgca
    18181 ccattctctc ggttaagagt aagttcgttg ttaaaaaatg aaatgagata gaaggaaggt
    18241 gagtccaatg gactacgata cttgttgata aattactata gctgttttta cggaagagct
    18301 ctcgataata ggagaaataa atcatgagaa aattagttaa aattggtgtt gcatctttaa
    18361 tggtatgtag tatacttgct tctacaagtg ttttggcagt atgggttgat ggtggtcaat
    18421 ggaactatgg agtaggatgg tcaggaaatt ttggttattc tgattattta cattctactc
    18481 gctctcatac agcaactgtt aaagatggaa ataaattctc taaggatcgt gcagaagctg
    18541 aggcatgggc tcgggcttca atcttcaaat tcccaccaac gggaatggaa tatttctatg
    18601 gattttaatt aaaattctcc ctcccctttt ggagagggag tttcttcacg ggaggtatct
    18661 ctatgaaaaa aatcagtcat ctttgtatgt tactcctgct tctgtgtacc actttttttg
    18721 tttttaatgt aaactataca cgagaagtgg ttcggattca agaaatggga aagactgtag
    18781 attctttgga tttgtatttg aaagatatta acgaacctgc agcgtctgtt cttcgatttt
    18841 ttgaggatgt atcaaaggag tataaagtct ccatcatcaa aacagacagt ggtgatgagg
    18901 tggtcaagtc tggtgttttt gataaagata ccttccccta ccaagagttt gggatttctt
    18961 ctcttgattt taccacagat ggtgaaggag tctatagtaa taaagaaatt tccaataaac
    19021 ttggtacgat tccgaccttt ctaaaagcca aacctattca gcttatgact tttcaaacct
    19081 atatcaagga tacatctcgt agtttaaatg gtcgctatac gataacttct acacaagaga
    19141 tggacaagga taggattgta cagaaatgga gcgatttttt caagatagac caggctacct
    19201 tgctagagcc gacctacaaa agtgcagtgg aagtcataaa tcgagatttg cttttatctg
    19261 ccattgtttt tgtcttggct attttgcttc ttgtgttagt gacagtgtat caaccgatga
    19321 tggagatgaa aagagttggg gtacaaaaat tacttggttt tcaagatagg gctgttttag
    19381 ctgatgttgt aaaaggcaac ctttacctcc tcctaggtgg ggctcttgtg atcaatctag
    19441 gcgtgttttt cttgcttgat tataagccaa aagatttgtt tcctatgctg tggttgtctc
    19501 attttttgct gttgcagctt tatctcttta tcagttggtt gacttacctc ttaatccaaa
    19561 aaatgacaat cagctctctg ctgaaaggtt tttcatcttt caaatttggt ctactcttta
    19621 attatttgat gaaaattgga actaccattt tactgacagt cttgctagtt ggggtaggaa
    19681 aaagtttgga gcaagaaaac aaagagttgg attaccagaa acagtggatc agccaaggaa
    19741 attatctgac cttagaaact ttccaactca atgataactt gtggcaagag cagttggcag
    19801 gctcagggaa ggcattggat tatttctatc gattttatca ggatttggta gaaaaaacgc
    19861 aggcgggcta tgtgcagagt agcagtcttc ctgtaaaaaa ttttgtccaa tcagaacaga
    19921 ttcagcaata tcagttaaca gatacggtgg atgtttacta tgccaatcgc aattttctaa
    19981 agagcaaggg attcaagcta ccagataccg gtattaaaaa agttattttg atgccagcaa
    20041 gtacgaaagg tgaagaagat aaaaatcagc tcttggggaa gttaattgcc tttcattcga
    20101 tgaagtatga agagcagcaa aaacgaacga tagaggagat ggatgtcgag attgcctatt
    20161 atgaaggaga ttggtcattt ttcccatata gtgataagcg aaaggaaaat ctctccaatc
    20221 caattattag cttggtcaat gattctgata tgatgtggga tgagaaagcc tccctgtcaa
    20281 caactggctt aaataatccg attaaaattg aaaatacggt tcaacatcaa aaagagatta
    20341 cagagttagt tgagaaattg tcagatggaa attatttaaa attttcatct attcaagcca
    20401 ttcaacaaga gaaagtggat tcttatcgag atgctgttcg gaattttaac ctactctttg
    20461 ctttgtttgg tctccttagc atgatgattt cctacttctt actagtaata actttcttat
    20521 tgaagcgcag ggatatcatt accaagaagt ttatggggtg gaaactggtc gatcgctacc
    20581 gtcctctcct cgttctgctc ttgctgggct atagtttccc tcttctagtc ttgattttct
    20641 ttgcccatgc gttcttgcca cttctgctgt ttgcaggctt tacatgtttg gatatactat
    20701 ttgtgctagt cttggcttct aggatggaga aaagaagtct agtagagtta ttgaaagggg
    20761 gcatcttatg attgagttgg aaaatattac caaaaccatt gggggaaaag tgattttgga
    20821 tcacttgtct ctcaggattg atcaggggga tttggtagct attgttggaa aaagtggtag
    20881 tgggaagtcg accttgttaa atttattagg tttgatagat ggtgattata gtggacggta
    20941 tgagattttt ggtcagacaa atctagcggt caattctgct aagtcgcaaa caataatccg
    21001 tgaacatatc tcttatctgt ttcaaaattt tgccctgatt gatgatgaaa cggtcgagta
    21061 caatctcatg ctggcgctga aatatgtgaa attgtctaag aaagacaagc tcaaaaaggt
    21121 ggaagagatt ttagagagag taggtttgtc atctactttg catcaaaagg tttccgagtt
    21181 gtctggtggc gaacaacaac gaattgcagt tgctagagcc atcttaaaac ccagccagct
    21241 gattttagcc gatgaaccaa caggttcgct agatcctgaa aatagagatt tggtcttgaa
    21301 gtttctctta gagatgaatc gcgaggggaa aacagtcatt attgtgaccc acgatgctta
    21361 tgtagcccaa caatgtcatc ggatcattga attgggcgag gggaaatgag tttgttcagc
    21421 tctttttgac tgactgaata ctcatgtttt tcagagagga atagcataaa tacgcctaga
    21481 aatgacattt ttatgtagta tttctaggtt tttttgtttc aaattgaaaa tttttccaat
    21541 ttaggcttga caaaggatga agataggtat attatttata caaccaaaaa gaataaacat
    21601 aaaggagact ttgttatgaa taagatgaag aaggtgttga tgacgatgtt tggtttagtg
    21661 atgctccccc tactatttgc ttgtagcaac aatcaatcgg ctggaattga agccatcaag
    21721 tccaaaggaa aattggttgt agccctcaat ccagattttg ctccatttga ataccaaaaa
    21781 gtggttgatg ggaaaaatca gattgtgggt tcagatatcg aattagccaa ggctatcgca
    21841 acagaactag gtgtcgaatt ggaactatct cccatgagtt ttgataatgt actggctagt
    21901 gttcaatcag gaaaagccga ccttgccata tcaggtgttt ctaagacaga tgaacggagc
    21961 aaggtgtttg acttttccat tccctactat actgcaaaaa ataaactcat tgtcaaaaaa
    22021 tctgacttga ctacttatca gtctgtaaac gacttggcgc agaaaaaggt tggagcgcag
    22081 aaaggttcga ttcaagagac gatggcgaaa gatttgctac aaaattcttc cctcgtatct
    22141 ctgcctaaaa atgggaattt aatcacagat ttaaaatcag gacaagtgga tgccgttatc
    22201 tttgaagaac ctgtttccaa gggatttgtg gaaaataatc ctgatttagc aatcgcagac
    22261 ctcaattttg aaaaagagca agatgattcc tacgcggtag ccatgaaaaa agatagcaag
    22321 gaattgaaag aggcagtcga taaaaccatt caaaagttga aggagtctgg ggaattagac
    22381 aaactcattg aggatgcctt taaagcatcc attgaaaaat agaaagaagg aaaagaacat
    22441 gagtaaagaa aaagtaattt tggcctattc tggcggtttg gacacatcag ttgctattac
    22501 ctggttaaag aaagactatg atgttgtttc agtttgtatg gatgtgggtg aagggaaaga
    22561 cttagacttc atccatgata aggctctcaa ggttggggca gtcgaatctt atatcattga
    22621 tgtcaaggac gaatttgcta cagattatgt gctagtggct cttcagtcac atgcctatta
    22681 tgaacaaaag taccccttgg tatctgcctt gagccgccct cttatttcta aaaaattagt
    22741 tgaaatagcg catcagacag gagcgactac aattgctcat ggctgtaccg gtaaggggaa
    22801 tgaccaagtc gaataccaga ttgcagtcgc taagaaagcg aatgaagcta aaaagtgatg
    22861 gagtgatggg ttcagaataa gaggttggtc gattggtagt ctctttcttg tcgttgaaaa
    22921 agtgagatat attgactttt gaaaaaaatg tcataattga gttgggataa acgtaaaagt
    22981 catactttct cgttaaatcg ttcggcgatt catggtgaca tggacacata gtagtaaaca
    23041 cactatgtgg cttggcagag ctaaaaactt ctggcttaac aatggctggt attaagaact
    23101 aacgaacaaa taatatgtaa agagtcgagg aaatccctcg acttttttta taatttcttt
    23161 ggttgataat gggtctctac ttcttttttg agatgagaca gcatagaagt ttcctcggtc
    23221 agctctagga gtgagaaccc tttttggata aatttagaat cgtctgtaca aatcccaata
    23281 cggacatagc agatagccag cctatcgtag cttttcttat tcttggcgtc ctctagtaaa
    23341 gtgtagcaga tttgcttaca catgttttta tcttgattgt atagatagag tgtggaaagg
    23401 ttgagcagga ttgctattcg caagtcatat aaatgttgat agtttttata gacttctaag
    23461 cgttgcaaga ttttctcgga ttattgacaa ataaacggac attctgatag acgattgccc
    23521 tagcggctta gtgtaaactt tacaaatttg gcttgtaatt tttttataaa attcacttca
    23581 gatacttgac agttattata ttttcgctta tgcttattat atagataaaa ggacgggata
    23641 ggagtttaaa aatttgaaag cgctatccat aataataacg cataattttc tccttttcgt
    23701 gaaaaaagtt aacgtaattt taaaatgagc ttaataagag gtactatgta ggtagaaaat
    23761 aaagatagga gaaaaagtat gaataaaaaa atattttgta ttctggtatg tattatatca
    23821 ttgattagtc tagctataat ctttccatgg ggctggtcga tataatgtaa gggagcttga
    23881 gttgttagtg gaggataaaa tgttaagagt aatagtagtt attcaatctt tagtaataat
    23941 actgcttgct gttgctttat tattatctcg gaaaaacttt gattcgttaa atgttgttct
    24001 tataatgatg atcgtatcac aattgttgtt attagtatat ttgataaaat cagggaatca
    24061 gtgattagct gttatttgaa ttaagtaaac tgttaagctt caagcagtaa ctggttttaa
    24121 atatttaaaa taagataaag gaaggaagtc taatttaggt aactaaacaa agcctgcgat
    24181 cacttgttag gaaactatcc taaccatgct taataaaaaa ggagaaaata aatggaactc
    24241 gtattaccaa ataattatgt tgctcttgag caagaagaga tgatgtatct tgatgggggt
    24301 ggtgttggtc gtaactggtg gaatagtaga ggtagttttg caacagtttt ggatgtaggt
    24361 ttggccatct atagtggtgg tgcaacaatt tattctgctt atgcgataaa aaaagctatc
    24421 tcagctaata gaggggctat tacgagaaca ttacgtagtt taataattaa acatgtaggt
    24481 agtgcagctg gccatttagt caatactgca ctaaacgttg cactaactgt tactggattt
    24541 tcactaggtg gagcaatcgc atatggggct gattgggctg acggtagctt agatggttat
    24601 atttttgctt aaaatgaaac atttttttgc aggaattggt gaaattcatt ttttgttatt
    24661 tttattatat ctaagcatgt ctgctagtcc aattattgga ctagtgattg gatatactaa
    24721 aataaatcta ataaattcta ttattatagc tcttggtatg atattggcat taattttggt
    24781 attatcaaga gtgtatagaa aatattttta tagagacgat gatgactaaa gtttttatca
    24841 ataatttggg ctccttgtca actgtagtgg gttgaagaaa agctaacgtc tggggaaggg
    24901 gttaaagctt tgctttatca aatattgact tacagagttg ctctattgta ttgatgtatt
    24961 cttagtaaat aatatggtgt tttgaatgaa agatgatcag aaatatttat tagcgggact
    25021 ttattcgctt ctagttgcaa tattttattt tccattgatt gagtccaagg ggatttttgt
    25081 aagtatattg atggcggttt tacttttata tttaatatac ttcattggaa cagtcattca
    25141 tattgtgata attaagttta taagaaaaaa atcttttaag tatttggttc tatatccatt
    25201 tacttatgat gggagctgga gatttcaacc tataaactta ctctactttc cagaaatggt
    25261 gagagatgtc attccgatta atttagttca agaatattgc caaggacaac cttacgggct
    25321 gttaaaaaag atgctgaaaa gaattcgatt gtcacgagag atagctttac tcctggctac
    25381 cattatcgtc tattttttta cgcatagaat tctacctctt tcagtattta cgttcatgtt
    25441 ttcttacata ttgatatttg cacaatctta tttgggtggt aatactgctt ggattggaaa
    25501 tagaagatta ataatagatg atgaatttga aaaaatcttg ctttcaaaaa gttatataaa
    25561 agaaatatca tctgcacgat actcggaata cttgacatgt gaatacaaaa accttacacc
    25621 aatcatattg ttagctattt ttgaaaattt acttgactcc tacttgcttc agaatcagag
    25681 tgaggttgac ttagatattt tttataaagt tttacctttg ctttataaag aaaaatatac
    25741 tatgggattc aattactttg taagtttaaa ttatttacta tataaggttg gatttttggg
    25801 aatcatttac gataatgaag cattaggaga tttgtcaaaa caatatttaa acagaaatat
    25861 ttcggaatta caagatggtt ctttcgaggg cggtatacaa gatgctgttg cctctaaaca
    25921 aatagtagtt ataaatgaat ttatagcttg tttaaattcc agatgcatgc catcccaata
    25981 tgatagattt ttttataaag atagacctta tattttttcc agaaagagtc ctattaagag
    26041 gtgaaaattt gttacatttg gattaacaag tgtcctaggg attagaaata actctagtat
    26101 agctagatat ttttgagtaa ctagaaatat cattaggcta cccatatgat tgccagaaaa
    26161 gatggctgat gaatcttatt tatactgttg cagtaggcgt tgtctaggat aaataagcta
    26221 tcttgatggg ggagattgga ataattttag tagaaacatt aaaggattat gggcaagtag
    26281 cacaggatta ggtgatgcaa tgtgctaagt tggcttggtg ttagcagtag tattatttaa
    26341 caatggaaag tagactaaat gaaaaataaa cgttattttt ttgacacaat tttaatgatt
    26401 ttactactta taagcacgat attttgtgtc agcccagtat ttataaaatt ggacatctta
    26461 ggaactccct ctcatgccat cttaaccttt gtattggcga taccgttatt ctatattttg
    26521 tctcaatgct tacatacttt gctattacta gtttcctcaa tcttttgtaa attaagacca
    26581 atttattttt attttatatt tgtgatcatt ataggagcta ggaaatacta tcgaattctc
    26641 tttcaccaac taatgggatt tagtccagga atagcagtgt tttataagga gagtcaaaca
    26701 actaagaatc tgtttaaatt ttactacttc ttgtacttta caacactaat ttcatactat
    26761 tttttcttta cttttgtgta tgacaaaccg ttgcttttgc ctcttattcc attttctatt
    26821 atcatagcat tagtacaaaa actttataga attgagaatc agcaattatt tctgttaaaa
    26881 tcaaaggtac taacaatact ggaatctaag aagaattgtg agtttaatct tcaggattat
    26941 catgaaattt ggaaattgca atcaaaatct gagttgccat gcgtggcttt atcttatatc
    27001 agtttgatca agccatatct ttcagagagc gtgcgtgaac aaattgattt attagaagtt
    27061 aagcgattta aaaaaataaa tcatccaata tcactttatg gtatgttgga tgttataaaa
    27121 ttaaatctat atttacggca ttataatgaa aaaataaata tgaatcaatg ttaaagaaaa
    27181 ttttagaggt aagaccagac tttgttttaa tcgagcagaa tattgatgat agtttaaata
    27241 gctcgcaacc attatcttta tctttagcta tttcagaaat ccaacttttg cttgaagtgt
    27301 atatagggat caaacatgtt tcaattagga gataaaacta gaataacatt tgctattata
    27361 ggggcaagtt gcatattagt cagtatgtat cttatacctc tcattaacac ggataataaa
    27421 ttttgggaaa tacttttatt tataataggt gtattgctaa ttggaattgc gttactaagt
    27481 caaaaaaaat aaattttgaa atagtattag tgagttcgca atcatttatt gctagtggtt
    27541 tagaactgtt aagtttcaag caataattgg ttttaaacct taggtaacct ataaaaacaa
    27601 ataaggtaga gaaaggatat cttatttagg taactaagta ctataaacac agtcgacaat
    27661 cacttgttag gaaaccatcc taactatgct taataaaaaa ggagaaaata aatggaactc
    27721 gtattaccaa ataattatgt tgctcttgag caagaagaga tgatgtattt tgatggggga
    27781 ttttctattc cgagatggcc tgttgcaaca gccattaata tagcttttaa tgatgtctta
    27841 ggtggaggag caatcagtct agttagaaat tatattcgta attatggttt gcggcgagtt
    27901 acaagcgcaa ttgctggagc agctgcaaga tatgttgggg tacgagttgc aaatagagtg
    27961 gcaggatttg cactgtctgc tattaatgga tttgcagctt ggatgtcaat tggcaatgct
    28021 attacaacaa tctgggccaa taatgatgta aataggagag acccaaattt aaacgccttg
    28081 tggtaactag atatgggtat taaaatggaa aaaatttttg ttattatttt ttttgtatgt
    28141 ctatttatat catccataac ttttttagcc tatgattttg ttagcgaaga aataaaaaag
    28201 ttgattattt ggatgaatgt cgtttttttg attttaatca tagcaatgat aatttatcca
    28261 aaattaagaa aatgataagg acactgtaaa attatgatac gtaaactaat cattttttta
    28321 ttaatgctcc ctctttttgt cttgtggcta gagttgcatg tcctagtgaa taacttacta
    28381 ttgaatctag aatctcccct tgattttgtg attagtatga gtcttgcttt ctgtagtttg
    28441 attttatcaa aaatagtttt agacatacta tacgcattga aagatttgta caagaaagaa
    28501 gctcttatta cgatttttcc ttttattttt ataggcagga agaaagtaaa tgtgaggttc
    28561 tcgccctatt tttcattcca tcgtaaaagt ttgtcgcctg atgatttaag atctaggatt
    28621 atatggagtt ttattcttga aattgctatt atcctagtat ttattttaaa aattcctttt
    28681 gcaatcatca tgcttactac aatatttttc tggactataa tggatatcaa tcatctcgtt
    28741 tttaataaga cggaatttct ttttaatcaa aacaaatggc aaaaagaaga ttcgtttgaa
    28801 agtgatttga cgaaaacgtt aaaggataag atacaaaaat cagagctaag ttattctgac
    28861 ttaatgtctc ttcagctgta tgatgcgatg aaccaatcca cctttttaac ggatagtgaa
    28921 ctttttgagg atattttgaa aaaaatcgaa gattctcata acacccttct gtgtacaggt
    28981 cttgtcgagt tactgctgta tgaaatttct attagtaaca ataacaactg gcaagaaaag
    29041 gttgataaaa ttagaataca gctcatcaga atcaatcaat tagatttttt ctattataca
    29101 agttggttaa ggcaaaattt tgatttctgt atgaatagag agtatcataa aatgaaatct
    29161 cggaaattat tactgagtaa taaaaagata gtttaagttc gtcctatttg taaaacaaat
    29221 gaaacaattt caactaagga ggagaaaaca aatggaactt gtattaccaa ataattatgt
    29281 tgtgattgat gaagaagaaa tgatgtatct tgatggggaa gcttatttaa gcaagcgtgc
    29341 ttgtcaagga atttgcgcag ctttagctat gagttcagga acttttatag cattagctgg
    29401 agctgcagtt ttaaccaaaa aactaataaa ctatattaag gttggaggtc ttggaggctg
    29461 gcttattggt gcagcagcag gtgtattggc tacagcagca gggaaaatag cttactatat
    29521 tggatatggt gttcttaata gaggttgtga tattaacggg aacccttatc cttgggatgg
    29581 attcatatct gcgacagtaa aatgagtaat gtagataaga ttcgaaaaat acacattatc
    29641 gtatgttgga tgtatatatt tttatcattc agggcgatta taaatgacac ggagtatttt
    29701 ttgcttattt ttttagcttt tatctactca atagtatcac tacctctata ttctgtgaaa
    29761 aataaaatag tatctatctg tctagccata aattcgattc tgttaatgag tttccccatt
    29821 ttaatcaata agtttttccc agaaagtttt ttgacttata ccgtattaat aagtgttttt
    29881 attacagagt tgataatttt tcatttaatt gggaaagatt ttgatattaa attgactaac
    29941 gaatataaga aaattagtca gtttagaagc aaggtgtctc aatctccttg gataaaatat
    30001 ttagagattt ctagttttat attaactata tttccatcta ttctttatgg tacagttgat
    30061 aatcatgtac tgactcttat ctttttgata aaaatttgtg cagataccac gataaaattt
    30121 ttattcatca gattatttga cacaagtact ttaatgaaga ggagaatatt ttttcttttc
    30181 gcattggatg ttatagctta cttattttta ggatatcttt tagtgattca aaaagcaggc
    30241 tatttgtttt cggttttact tcttttttct aatttttcag ttccatttat caaagaaaag
    30301 gaattcgaat tatttaaaaa tagcaagtaa tagaaacata ggttaaatct tagaacggct
    30361 taaaatcaga tatgataaag ggaaatagtc ttatctaggt aactaagtgc tacaaacaca
    30421 atcgaggatc acttgttagg attacatttt aatcatgctt aataagaatg gagaattcct
    30481 atggggattg tattactctg aagtttcgaa taccttagtt ctcgtgattt tgagctattc
    30541 taggtttaga atccttcaga atgtaaaatt ttaagcagtc aaagacttag aatagcccga
    30601 aaacatttat tttatagcaa ttctaggctt agaattgctc atatatatgt atttgagctg
    30661 ctcgatagtt aggatagctc tattctgaga aatctgagct atcaatgctt cagaatagta
    30721 ttcgccaatg gtttttattg aagaggtgat tgttttatga tagtctaaaa taaaactgat
    30781 ttaatagagt aaatggagaa tcgttacatg aaacattttt ttgcaggaat tggtgagata
    30841 aaacttgttg gctacttatt gtatatatgt gtaggactag ctcctctttt tcatatatat
    30901 gtcataggtt cggaactgag ttttgtgaaa atagtgttat ctattttggg agttatattt
    30961 gtaagtatgt taactattgc tcgaatttat cggacttttc tataaagaat agtttggact
    31021 tgaactgtat ctaaaaacag aggttagtcg attatcagcc tctttcttgt cgttgaaaag
    31081 agtgagatat attgactttt gaaaaaagat gtcataattg agttgggata aatctaaaaa
    31141 taatatagta gattgaatct ggaatagtcc gttatgactg ttaaaatatt tctagaaatt
    31201 aatttgactt tcctaatcga tttgttcata tcttgtttca atctactata ctttctcgtt
    31261 aaaccgttcg gcaattcatg gtgacatgga cacatagtag taagcacact atgtggcttg
    31321 gcagatctaa aaactgttcc cttgcgataa gcctaataag cacaacatag ggagttagag
    31381 aagccgactc taatcaacca ctttgggcag tagtgagaac tgccccgtgc tttttatttt
    31441 gagaaaatat ggagtttgtc gttgaaatta cttgattgta ttttggatta tcaagaaaga
    31501 ttcaatggaa aaacatgtca agtatcaacg aattataagt atttagagac tttcaaagtg
    31561 aatttttgct tgactgattt acatcattta tttgacttac acaaaatcac acgagattat
    31621 gctagtcaaa caaaacctgc tattcaagct ggtgttttta ttttagaaga ttttagaaat
    31681 atcctatgta caatgatgta atcgaaagga tatctttatg tgagtttatc ggcgatatct
    31741 tctatatcta agctagcaag ttgttgcatc gtagctaagg atttatctaa aaatactatg
    31801 aaattggacg tcatattttt tgaggataaa aataaaagat ccgcagtttt aggtttacga
    31861 agagacaaaa gcggagtatt taaaccagtt actctacatt ttacaagcgc taagaaatat
    31921 gctaaagttc gtaaaacaga tgtgaaagaa atgaaatggc tataaagatt gtccgcaggc
    31981 ttaagcttgc gttttttgtt gtttaacgaa attaaaaaac aagctctctc atcggaaatg
    32041 tttttatagg aatgaaggaa gatgatgcta tgtttaaaaa gagaatcgaa aagggcaaaa
    32101 gtagtgtctt tatctttttg gagtagaagc ttatgatata gaaatttgta ataaaaatgt
    32161 aatataaaac atttgacaaa tatttacggg gggagtatac ttaatataag tatagtctaa
    32221 aaatgactat cagaaaagag gtaaatttag atgaataaga aaaaaatgat tttaacaagt
    32281 ctagccagcg tcgctatctt aggggctggt tttgttgcgt ctcagcctac tgttgtaaga
    32341 gcagaagaag cccccgtagc tagtcagtct aaagctgaaa aagactatga tgcagcgaag
    32401 agagacgctg agaatgcgaa aaaagcttta gaagaagcaa aacgtgcgca gaaaaaatat
    32461 gaggatgatc agaagaaaac tgaggagaaa gcgaaaaaag agaaagaagc ttctaaagag
    32521 gaacaagctg caaatctgaa atatcaacaa gagttggtta aatatgctag tgaaaaagat
    32581 tcagtaaaaa aagctaaaat tctgaaagaa gtggaggaag ctgagaaaga gcataagaaa
    32641 aaacgagcag aatttgagaa agttagatca gaggtaattc ctagcgcgga agagttaaaa
    32701 aagactagac aaaaagcaga agaggctaaa gcaaaagaag cagaacttat taaaaaagta
    32761 gaagaagctg agaaaaaagt tactgaagcc aaacaaaaat tggatgctga acgtgctaaa
    32821 gaagttgctc ttcaagccaa aatcgctgag ttggaaaatg aagtttatag actagaaaca
    32881 gaactcaaag ggattgatga atctgactca gaagattatg ttaaagaagg tctccgtgct
    32941 cctcttcaat ctgaattgga tgccaaacga actaaactat caacacttga agagttgagt
    33001 gataagattg atgagttaga cgctgaaatt gcaaaacttg aaaaaaatgt agaatatttc
    33061 aaaaaaaccg atgctgagca aactgaacaa taccttgctg cagctgaaaa agacttagct
    33121 gataaaaaag ctgaattgga gaaaactgaa gctgacctta agaaagcagt taatgagcca
    33181 gaaaaaccag ctgaagaaac tccagctcca gcaccaaaac cagagcaacc agctgaacaa
    33241 ccaaaaccag cgccggctcc tcaaccagct ccagcaccaa aaccagaaaa aacagatgat
    33301 caacaagctg aagaagacta tgctcgtaga tcagaagaag aatataaccg cttgccccaa
    33361 cagcaaccgc caaaagcaga aaaaccagct ccagcaccaa aaccagagca accagttcct
    33421 gcaccaaaaa caggctggaa acaagaaaac ggtatgtggt acttctacaa tactgatggt
    33481 tcaatggcga caggatggct ccaaa
//
LOCUS       DAVBNZ010000019        32119 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000019 DAVBNZ010000000
VERSION     DAVBNZ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.019"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(181..1359)
                     /locus_tag="VQ860_000942"
     CDS             complement(181..1359)
                     /locus_tag="VQ860_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3119389.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            1639..2901
                     /locus_tag="VQ860_000943"
     CDS             1639..2901
                     /locus_tag="VQ860_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3119390.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWSVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDSGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            2904..3800
                     /locus_tag="VQ860_000944"
     CDS             2904..3800
                     /locus_tag="VQ860_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET3119391.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            3815..4132
                     /locus_tag="VQ860_000945"
     CDS             3815..4132
                     /locus_tag="VQ860_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3119392.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            4149..4465
                     /locus_tag="VQ860_000946"
                     /pseudo
     CDS             4149..4465
                     /locus_tag="VQ860_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
     gene            4475..5077
                     /locus_tag="VQ860_000947"
     CDS             4475..5077
                     /locus_tag="VQ860_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3119393.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGRKGGISSSCWGSVVVTSSERLLETSLR"
     gene            4983..5609
                     /locus_tag="VQ860_000948"
                     /pseudo
     CDS             4983..5609
                     /locus_tag="VQ860_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
     gene            5624..6394
                     /locus_tag="VQ860_000949"
     CDS             5624..6394
                     /locus_tag="VQ860_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET3119394.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(6672..6959)
                     /locus_tag="VQ860_000950"
     CDS             complement(6672..6959)
                     /locus_tag="VQ860_000950"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3119395.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            7163..7435
                     /locus_tag="VQ860_000951"
                     /pseudo
     CDS             7163..7435
                     /locus_tag="VQ860_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7545..7748)
                     /locus_tag="VQ860_000952"
     CDS             complement(7545..7748)
                     /locus_tag="VQ860_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3119396.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7779..8387)
                     /locus_tag="VQ860_000953"
     CDS             complement(7779..8387)
                     /locus_tag="VQ860_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3119397.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(8426..8596)
                     /locus_tag="VQ860_000954"
     CDS             complement(8426..8596)
                     /locus_tag="VQ860_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET3119398.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ860_000955"
     CDS             complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ860_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET3119399.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(9258..9422)
                     /locus_tag="VQ860_000956"
     CDS             complement(9258..9422)
                     /locus_tag="VQ860_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3119400.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIIGAAIVI
                     TVVSFFTGRK"
     gene            9865..11346
                     /locus_tag="VQ860_000957"
     CDS             9865..11346
                     /locus_tag="VQ860_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3119401.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            11708..12703
                     /locus_tag="VQ860_000958"
     CDS             11708..12703
                     /locus_tag="VQ860_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3119402.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            12830..14140
                     /locus_tag="VQ860_000959"
     CDS             12830..14140
                     /locus_tag="VQ860_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3119403.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            14236..15138
                     /locus_tag="VQ860_000960"
     CDS             14236..15138
                     /locus_tag="VQ860_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3119404.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMINLVQRRVLKEDD"
     gene            15140..15985
                     /locus_tag="VQ860_000961"
     CDS             15140..15985
                     /locus_tag="VQ860_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3119405.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            15995..17314
                     /locus_tag="VQ860_000962"
     CDS             15995..17314
                     /locus_tag="VQ860_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3119406.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(17524..17596)
                     /locus_tag="VQ860_000963"
     tRNA            complement(17524..17596)
                     /locus_tag="VQ860_000963"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17561..17563),aa:Lys,seq:ctt)
     gene            complement(17861..19132)
                     /locus_tag="VQ860_000964"
     CDS             complement(17861..19132)
                     /locus_tag="VQ860_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET3119407.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            19402..19641
                     /locus_tag="VQ860_000965"
     CDS             19402..19641
                     /locus_tag="VQ860_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119408.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            19806..19985
                     /locus_tag="VQ860_000966"
     CDS             19806..19985
                     /locus_tag="VQ860_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119409.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            20122..20300
                     /locus_tag="VQ860_000967"
                     /pseudo
     CDS             20122..20300
                     /locus_tag="VQ860_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            20337..20789
                     /locus_tag="VQ860_000968"
     CDS             20337..20789
                     /locus_tag="VQ860_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET3119410.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            21080..21550
                     /locus_tag="VQ860_000969"
     CDS             21080..21550
                     /locus_tag="VQ860_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET3119411.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            21569..22657
                     /locus_tag="VQ860_000970"
     CDS             21569..22657
                     /locus_tag="VQ860_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET3119412.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            22638..23066
                     /locus_tag="VQ860_000971"
     CDS             22638..23066
                     /locus_tag="VQ860_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3119413.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            23201..24154
                     /locus_tag="VQ860_000972"
     CDS             23201..24154
                     /locus_tag="VQ860_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET3119414.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SIFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            24156..24899
                     /locus_tag="VQ860_000973"
     CDS             24156..24899
                     /locus_tag="VQ860_000973"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET3119415.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            24910..26706
                     /gene="pepF"
                     /locus_tag="VQ860_000974"
     CDS             24910..26706
                     /gene="pepF"
                     /locus_tag="VQ860_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3119416.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(26766..27443)
                     /locus_tag="VQ860_000975"
     CDS             complement(26766..27443)
                     /locus_tag="VQ860_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3119417.1"
                     /translation="MKPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            27690..28460
                     /locus_tag="VQ860_000976"
     CDS             27690..28460
                     /locus_tag="VQ860_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119418.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGDGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFWGLTGTEKEDLHV"
     gene            28453..29217
                     /locus_tag="VQ860_000977"
     CDS             28453..29217
                     /locus_tag="VQ860_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3119419.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            29641..30432
                     /locus_tag="VQ860_000978"
     CDS             29641..30432
                     /locus_tag="VQ860_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET3119420.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALVYANLLSVDANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLKEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVD
                     FPIEEREDFYKFSNFRTCLLEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            30543..31211
                     /locus_tag="VQ860_000979"
     CDS             30543..31211
                     /locus_tag="VQ860_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET3119421.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(31465..31998)
                     /gene="queF"
                     /locus_tag="VQ860_000980"
     CDS             complement(31465..31998)
                     /gene="queF"
                     /locus_tag="VQ860_000980"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET3119422.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         9733 a         5259 c         6723 g        10404 t
ORIGIN      
        1 gatcgattcg tcctgttatt atttcatttc actatacatt atgaaaaagg ggagatagga
       61 gtataattcc aaatataaag aaagcgaaca aaacagaatt ctgattttca gaaaacaggt
      121 ttattcgctt tttatgatat actccctctt tttagcctat ttattaaatg taatagaaaa
      181 ttaagaatgt agaattgtat gatacaaaca aagtgcaata gctgagtgtg cggctgtaaa
      241 atcattgtaa ggttcaataa tgacttcagg taggcgatta tagagcagtt tgggtttgta
      301 gttcatttca ctatatagtt tttggatgat gtgttgattt gttagtaaag gactatgtag
      361 gtagattttt tgagagtcaa tcatcatact gatatttaaa atggtttgac taagatagag
      421 taaggcttga tggataagtg tgattattcc agtgtcacct aattgataag cggttaaaat
      481 aacttggata tcaatatcat cggcattttt gactaaacta ggaagtagag aatagggaga
      541 ttgatgatat agaatttttg attttttgat taaccaagat tctccagcaa aagtttgtaa
      601 gcatcccttg cgcccgcagc tacattcttc tccctcagat gaaacaactg tatgccctat
      661 ttctccaatc attagatttc ctttcccata aatgtttccg tcgtagatat aagaacagtg
      721 catacctcta gcaaaatgaa aataagcaaa attagggtca ttctgttggc gactaaatag
      781 gcgtttacct atagccatac agttaacatt gttagagaaa aacaaaggct tatcaaagtg
      841 ggattgaatc atttctaagt cgatatgttg ccataaagga ttgtttgttg ttattttata
      901 atcatctaaa tagcgaccag gtagcgcgat tccaattgct tctatttcat aatcagagca
      961 gttatttaag aattgcttta gtgtctggtt aatgagttga tttccctttt cttggattaa
     1021 ctgtttagta acaatttctt tctcttcctt taagatattt cctagattat ctcctaaagc
     1081 aaaagtgaaa tgtttttcag atagttcaca accaatgtag taaaatcgtt tagcttgaat
     1141 gtctagcagg attttttttc tccctacgct tgtatcgtgt tcgtcttcac caagttctaa
     1201 gagaatattt tctttaatca gatcatttgt gatactgcta gttgttgcag gtgttattcc
     1261 tgttttagta gcgatttcaa ttcgtgaaat gggacctaat gtgtaaactg tttccagtat
     1321 tttagctctt agttgtaatt gtttcttaga taaggtcata ttagttttct tcctagttgt
     1381 cagattctta aaatcctatg attttttgct atggataaat gtagatgtta atctttttaa
     1441 gcttttcatt acttactggt ctctttttat tatatattga taataaaaaa taatcaaatg
     1501 tttacacaaa tccttgacaa ggctttctta tagttgtaaa atataaataa caaaagataa
     1561 tcaaataaca acttgacgtc aaaaaataaa gataattgat aacttttgat aataaaatat
     1621 atttaagagg aaaaggttat ggaaaaatta ttacaagaaa agttacttcc agtagcggct
     1681 agattgggta ataataaagc gttggtttct attcgagacg gtattactct aactatacct
     1741 ttattgttga taggttcatt actaatggtt attgcaagtt ttcctattcc aggatgggaa
     1801 aaatatctgg gtgatattgg tgttgctgac tatttatgga agggtgttga tagtagtttt
     1861 ggattacttg gtcttgtagc tagttttggt atcgcttact ttatggctag acaatacaaa
     1921 gttgatggta ttcctgctgg tattgtgtca ttatcatctt ttattacagt tacgcctttc
     1981 attagaggag aggctggagc aggaatgcct accgctttca tggcatcaaa aggtttattt
     2041 gttgctatga ttttaggatt gattaatggc tatatctacc aatggtttat aaatcataat
     2101 atacagataa aaatgccgga tggtgttcca ccagcagtat ctaaaagctt tagtgccatt
     2161 attcctggtg cagtgactat tgttggttgg ttgattgttt atgcaacttt agataaatta
     2221 agtttaccta atcttcatga aattgctcaa gtagctttgg gaggtccact tggactttta
     2281 ggaaataatg ttattggtct tcttatctta attttcctta atagtagttt ttggtctgta
     2341 ggattacacg gaggaaatgt tgttaatgca gttatgaaac cgttatggtt agctaatcta
     2401 gatgcaaata aagtagctta tcaaactgga gaaactcttc caaatatttt tactagcgta
     2461 tttatggata attttgtatt cataggtggc ggtggtgcaa ccataggttt agttcttgcg
     2521 ttaggatatt tagcacataa gaagaaagct agtaaacaac taaaaacttt ggcacctata
     2581 actgttatac ctggattatt taatataaat gaaccagcaa tgtttggcgt tcctattgtt
     2641 ttgaacattt tgttactagt tccatttatc ttagctccaa tgtttaactt actagtagcg
     2701 tggggagcaa tggcatcagg tttggttccg ctaacttata cagattcagg ttggactatg
     2761 ccacctgtta taagtggttt acttgctaca ggaagtattt ctggttcatt attacaaatt
     2821 gtattgattg ttttggatgt cttactttat ttaccatttg taatagctat tgaaaaacgg
     2881 tttaagttat tggaggattg agaatgaaac gtttaattag tgcaaatcca tctgagatat
     2941 tacagatgaa tgctgaagaa ttaaaacaaa gtattttagc aagtgaaggt agagttgttc
     3001 tatctgaaaa tgtagttact cgtgagacat ttgttgggga tataactaat tctgaaattg
     3061 ctagagcttt tggagctgat atgattttat tgaattgtgt tgatgttttt gagcctaaaa
     3121 tttatgcttt ggatagttca ggtgatgatg ttattcatcg cttacaccag cttgttgctt
     3181 gtccaattgg tgtaaatttg gaaccgattg acccatctgc aaagatgcta gaggaaacac
     3241 aggaaattgt tgcaggtcgt gttgctagtg ttgaaacatt gaatcgaata gaggagttag
     3301 gttttgactt tgtctgtttg actggaaatc ctggaacagg agttagcaat cgagaaatca
     3361 ttaaggctgt tcaaactgct aaggaaaact tttctggttt gattattgca ggtaagatgc
     3421 acggggcagg agtgaatgag cctgtggcag agctttctgt cgcagagcaa ttgttggaag
     3481 caggtgcgga tgtgatactt gttccagcag ttggaaccgt tccagccttt catgaccaag
     3541 agttgcgtga agtcgttgat ctcgttcata gtaagggtgg tcttgtattg agtgctattg
     3601 gtactagcca agaaacatct gatacagata ctattaagga aattgcactt agaaataaaa
     3661 tttgtggagt tgatattcaa catataggtg acgcaggata tgggggactg gcaacagtcg
     3721 ataatattta tgcattgagc aaggcaatta gaggagtgag acatacagta tctcgcttgg
     3781 ctaggtcagt aaataggtga taaaggagta agctatggct aaagtaacaa ttatgttagc
     3841 atgtgcagca ggtatgagta caagtctgct agtgacaaag atgcaaaagg cagcagaaga
     3901 taaggggttg gatgcagaaa tttttgcagt tccagctcct gaagcagaag aaattgtagc
     3961 aacaaaagaa gtaaatgtgt tgcttttagg cccccaagtt cgctatttac taggggactt
     4021 tcaagaaaaa ctaaaagata gacagattcc tgtggcggtt attccgatga cagattacgg
     4081 aatgatgaat ggttctaaag ttttagattt agctgaaagt ttattagact aagattgagg
     4141 agaatgttat ggatgaaagt aatttagaat ctgtaatggg gctaattatg tatggtggag
     4201 atgccaaaag taatgctatg gaggctattc aggcagcaaa aaaagggatt tctctaaagc
     4261 caatcgaaga ttagctgatg cgaatgctgc cttattacag gcgcataagg ctcaaacaga
     4321 aatgttgaca agagaggcac aggggggaaa aacatcaatt agcctcttga tggtacacgc
     4381 gcaagatcat ttaatgacga gtctgacttt tgttgacttg gcgaaagaag tggtagaagt
     4441 atacgaacga tttgaaaaaa attaggagtt tggtatgaat acaatgttgg ataaaatgca
     4501 agaaaaactt tctccaattg caatgaaagt tgggaatcag aagtttttag ttgctttacg
     4561 tgattcattt gtggggacta tgcctgttat tatgacaggt tccattgctt tgttattaaa
     4621 tgcttttcta gtggatttac cacaacaatt tcacctagaa agtattacga aaacctttca
     4681 gtggcttgtt gacatcaata atttggtatt caagggaagt ataccaattg tttccttgtt
     4741 gttcatctat tgcttgggag tgaatatcgc taagatttac aaggttgata cagtttctgc
     4801 tggtttggta tcacttgctt cgtttgtcat ttcgattgga agtacagtta caaagagttt
     4861 ccctttggca aatgtaggag atgtgaaatt agatcagatc ttacaaggaa ttgataatct
     4921 agcatttgat ggtaaaaatc tgatggtaac tattgggaat gtgattccag gaaaccatat
     4981 taatgccaga ggcagaaagg gagggatatc ctcatcctgc tggggctccg tggtggttac
     5041 aagttccgaa cgcttgctgg aaacatccct acggtgagaa tagtaatcta gtgggtttag
     5101 aagaccatcc agtagttcat gttgctttag aagatgcatt ggctttctgt aattggagcg
     5161 gaatgtcttt accgactgaa gcacagtggg aatatgctgc tagaggagga agacaatctg
     5221 aatatccttg gggagatact cttttagaag gtggatatta tcatgccaat acttggcaag
     5281 gaagatttcc ttatgaaaat actgtctcag atggatttat aggaacggct cctgtctatg
     5341 aatttttacc taatgatttt ggtctatatc aaatgattgg gaatgtttgg gaatggtgtc
     5401 gcaatccgag atatacctta ttagctagtt ttaatgaaga tgactatgag ttgccaaaat
     5461 atgggataca agatgaggag tatgctatca gaggaggttc ctttttatgt cattgttctt
     5521 attgtaatcg ataccgagta gctgctagaa atggatgtat ttctacttcc actagtagcc
     5581 atctaggttt tagatgtttg aaagaatagg atggacttaa aaagtggttg agattattta
     5641 ttttctaatc attataatag ctagtggatt gggttctata tcaggcatgg gtggtggaat
     5701 tataattaag ccacttatgg atagttttgg gtaccattcg gtcagtgata ttgcttttta
     5761 ttctagtttc tctgttttta taatggcgat tatttcaaca atcaaaagat tttcacaaag
     5821 taaagagata aaatggagat tgatttttac ggtatccttt tcttctgttt taggaggatt
     5881 tctaggtcat cttatttttc aagttttgtt atctcaatta tcagtacggc tagtatccat
     5941 tgttcaaatg attttactat ttgtgatgct acttgtatca tttgttttaa cagattttaa
     6001 aaaaacttat caatttgata agataggatt ctatatgatt tgtggtcttc tattgggctt
     6061 aatttctagt tttttaggga ttggtggtgg tccgctcaat gtatctttat tgatggtgtt
     6121 tttttctatt tcgataaaag aagcaacgat gtattctctt gcaattattt tcttttccca
     6181 gctgtctcat ttggctacaa ttgttgtggt tacaggttta aatcagtatc atttagcacc
     6241 tgttccagtt atttttcttg cttctatatg cggaggggta ttggggacgg ttgtatcaaa
     6301 agtcttacct gaaaattggg taagatactg ttttaaaggg atgttattct ttgtcatggg
     6361 aatgacttta tataatttat ttcatatttt gtaaggtcag tgtgaaaata tttaaataga
     6421 cttcctgtaa aaactggatt taacgccctc catttgtcaa attaagctag acagtcttac
     6481 caactcagaa aatatctgat gaggtatttg gtatccaaag gatttaggtg ggatgtgatt
     6541 tcttgaggct gggaaaaagt ctttaaaatt aaaaaatgca taatatcagg tgttggaaaa
     6601 actttgatac tatgcgtttt attgtgggaa tatttatttc attttctcct gaaattgagt
     6661 ttttgtccag cctaaaattc ttgactgact tcgttgaaat ctgtctgctt tggcaagtca
     6721 tgacacctta aaagtctatt tgaatgttcg ttgagacacc gctgtcttga acatcctaga
     6781 ttcgcaaaaa agctctcact atcgtgatga ttggaaatat ctttccattt tgaaaactct
     6841 tttccacagt caaacgtaat agatttaaag aggttcacta gaaattgtgc cagccaccct
     6901 tggatggatt ctgccatatc ctttgcctta cgactcttgg tcttcaaact gacaatcaat
     6961 tgactatacc tgttcgctca caaataggag agaactgttt acgaaaatct aatgaatatg
     7021 ccacaagaac attataccgc aacgtgtact atttttggtt cattttacta tagaaactat
     7081 tgaagaacct gtacgaaaat atatcatgaa aaagggtaga tagaaagcaa acagccttga
     7141 aatcaatgtt gactgcgatt atgaacctga atcagcccct caaaagggac tgtatatgaa
     7201 tgaacgttac cagtgtttaa aaactaaaga atatcaggca cttttatctt ccaagggtag
     7261 acaaattttc gctaaacgta agattgatat gaaatctgtc tttgggcaga taaaggtttg
     7321 tttgggttat aagagatgtc atctgagagg gaagcgtcaa gtgagaattg acatgggatt
     7381 cgtactcatg gccaacaacc tgctgaaata taataagaga aagaggcaaa attaaaaagc
     7441 tagagttccg caattgggaa tccctagctt tttgttttct gagaatcatc ttgactcaga
     7501 ctcttttgac taatgttact aaaaagataa agtaactttt aaccttattt atcgtcgcca
     7561 ctcaacatgt ttttaacacc ttctacagca ccttctacag cgtctttggc atcttcggcg
     7621 acttctttta ctttagaaac aactttttca gctgctcctt ctttttccat tttttcatca
     7681 ccgatggctt tcccaacacc ttctttaata gaacctttag cttgatttaa tttttcttct
     7741 actgacatga taatttctcc tgttatattt attttatctt agtttacacg agtgttttcg
     7801 tgagatacta caccatttgc tgcaccttta acagcttcta caccttcgct aactttttct
     7861 tgaacagttg agaaaccaga tccaagacca gatttagctt tttcgaattg ttctgaagtg
     7921 aattctcctg ttgattcagc aacgtcagat acgcgatctt gaaggcttac tgagtctgct
     7981 tcatgctgtt ctttagtttt gatgtcgaca acgtttacgt tgatttcaac aatttccaag
     8041 tcagtcattt tagcaacttc tgaagatacg atttctctga tttctgaata taaagctgga
     8101 acattttttt ggtactcaac aataacgttt aagtcaactg caacttgtgt tttaccaact
     8161 tctacgttaa caccacttgt tacgtcatcg ctgttaacga ttttttcttt aagatttgag
     8221 aagaaaccac catcgattcc caaaagacct gaaacgtttt ctagtgaaag accaatgatt
     8281 ttttggataa ctttatcttc gtaagtaagt tcccctttga tttcgtgagc tacaacagta
     8341 gcatctttct tttctacgtt agtgtttgtg tttttttcgt ttgacatatg aaactccttt
     8401 aattaaatta gtaattttta tttttttatt tatctatata gtttttttcg atatataatc
     8461 cagctgcaac tcccagtgct cctaaaatca atacaaatat tgttttgaag aagccaaagg
     8521 agacaatcaa acaagccaga aatacgccta tgagaccagc gataattgga tatcgatatt
     8581 gtttaagcca ttccattttt tacttcctta cttcacacga ctaacagtct ttttgttttg
     8641 aggttttggt tggtaatttt ttactgcaac ttcaagtttt acttgacgct caataccaaa
     8701 aaactgcttc aatccattag ttatttcatt ttgaattatt tggcatctgt cagcgatgtt
     8761 gtctgaagga agaattttac cttctacatg aacgaaacat ttattttttc gtaaatttac
     8821 atgaacagtt gggttcttga tcaatctatg atcactcacc aaacttctaa caaaaccttc
     8881 gattgccgaa ttctttaatt ttaatgtatc gtttttagtt tcaagttgga tttccaagta
     8941 acgtttagga taaaacatca caactaaaat ggataataaa actaaagttg atagaaccac
     9001 tgtcccccaa aagacatatc tagcaagata gaattcaact acggagttct gtctccagct
     9061 aagtagatga atacctagat cactaacttg atgataatct atcaaaacag gaaggaaaat
     9121 tgtcaagatt aaaatacaga aaataatgaa acatattttc tttgcttttg acatatacaa
     9181 tcctttcgat ttaacattta aactattttt cccgtcattg atttaaaaat agtttgctaa
     9241 ctttactggc gaaaagttta ctttctacct gtaaagaatg acactacagt aatcacaatc
     9301 gctgcaccta taatagatgg gagcaaagcc attccagcga ttgatggacc ccaactacct
     9361 aaaagagatt gtcctgcata tgccccgact aaaccagcga atacatttgc gatgattccc
     9421 atagaactac ttttttagtg attttacctg ccaagagacc aataagacct ccagcaataa
     9481 ttgatcacaa cactgcctac cctccttttt tattttaata tcaaaaaatc aatttctttg
     9541 attaatacta ttatataact ttaatataga aaagtcaatt atttcgattg ttattattat
     9601 ataattttaa aaaatcaaat tctttaattg ttgctattat ataattttta aaattaaaaa
     9661 tataatcttt agacttgaat ttgattctgt attcacgccc tcaatagacg gtaaaataag
     9721 aaaattgttt atatattgtc tccgtagtgt tattatacga aataaaagat tttaggaaaa
     9781 gtcgttatat catgctatac ctattctttg tggtataatt gcaagaggtt taatccgata
     9841 atttataaag agagaaagat attcatgaga gatttattat ctaaaaaaag tcataggcaa
     9901 ttagaattat tagaattatt atttgaacat aaacgttggt ttcatcgttc tgaactagca
     9961 gagttattaa attgtacaga acgtgcagtc aaagatgatc tatcccatgt taaatctgct
    10021 tttcctgact tgatttttca ttcttctact aatggtatac gcattattaa taccgatgat
    10081 agtgatattg aaatggttta ccatcatttc tttaaacatt caactcattt ttcgatttta
    10141 gaattcatct tctttaatga aggttgtcaa gctgagagta tttgtaaaga attttatatc
    10201 agttcatctt cgctctatcg tattattagc caaatcaata aagtgattaa aaggcaattt
    10261 caatttgaag tcagtctgac ccctgttcaa atcattggaa atgagagaga cattcgttac
    10321 ttttttgcac aatatttttc agaaaaatat tatttcctag aatggccatt tgaaaatttt
    10381 tcatcagagc cactatctca attgttagaa ttggtttata aggaaacaag ctttccaatg
    10441 aatttgtcaa cgcatagaat gctaaagttg ctcctagtta cgaacctata tagaataaag
    10501 tttggtcatt ttatggaagt agataaagat tcttttaacg accaaagttt ggatttttta
    10561 atgcaggcag aaggaataga aggtgttgct cagagttttg aatcagaata caatatctct
    10621 ttagatgaag aagttgtttg ccaattattt gtgtcttact ttcaaaaaat gtttttcata
    10681 gatgaaagtc tctttatgaa atgcgtaaaa aaggatagtt atgttgaaaa atcttaccat
    10741 ctattgagtg attttattga tcagatttca gtcaagtatc agattgaaat ggagaataag
    10801 gataatctga tttggcatct gcataatacc gcacatctgt atcgtcaaga gttgtttact
    10861 gagtttattt tatttgatca aaaagggaat acaatcagga actttcaaaa tatttttcca
    10921 aaatttgttt cagatataaa aaaagagctt tctcactatt tagagactct tgaggtttgt
    10981 tctagttcaa tgatggtaaa tcatctatct tataccttca tcactcatac caaacatttg
    11041 gtgattaatt tgctacaaaa tcagcctaaa ctaaaggttt tagttatgag taattttgat
    11101 cagtatcatg caaaattcgt tgcagagaca ctttcttatt actgtagcaa taattttgaa
    11161 ctggaagttt ggactgaatt agaattatca aaggaatctt tagaagattc accttatgat
    11221 atcattattt ctaattttat tattcctcct attgaaaata agagactcat ctattcaaat
    11281 aatataaaca cggtctcact catatacttg ttaaatgcca tgatgtttat tcgattagat
    11341 gagtaaccaa aaataacaaa aaaacgctat ttcgcgtttg aactgtacct caaaagttag
    11401 acagaaaaaa tctaattttt ggggtgtttt tgttaagaaa agaccttcaa tcatttaagc
    11461 aaaatgtaca tctagattta tagccctcta aaactcttgc tttttttgta gaagatacga
    11521 aaaaagccat aaaaccaagg cttttcctgt tttatgtaga tgtttacaca tgaaaattga
    11581 agtattttca aaagctaatt ggagtgattt tattcatgat gggataaatg atctggccaa
    11641 aaatgattga gaaatagttg cttaaaaagc atttgcatga tactatatat tgaaaggagg
    11701 tgataatatg gtagaacaaa gaaaatcaat taccatgaaa gatgttgctt tagaagcagg
    11761 agttagtgtt ggaactgttt cacgtgtaat taataaagaa aaaggcatta aagaagtaac
    11821 tttaaggaaa gttcaaaggg ctataaaaac attggactat atccctgata attatgctcg
    11881 aggtatgaaa aagaatagaa cagaaactat cgctttgatt attccgagca tatggcatcc
    11941 atttttttcg gagtttgcct atcatgttga gaaagagtta ttaaaatata attataaatt
    12001 atttatttgt aacgctgata gcgattcaca aaatgaaatc gaatatatcg aaatgttgaa
    12061 acaaaataaa gtggatggaa ttattggtat tacatattct gatattgaca aatatatttt
    12121 atctgattta ccgtttgtaa gtatagatag acatttttcg gaaaatgtat gctatgttac
    12181 ttcagcaaat tacaaaggag gacaaactgc agcagaggaa ctggttagaa gggataataa
    12241 gcaccttgct tttattggtt caattaatat gtatgagaat gagactatac tcagaagtaa
    12301 aggattcaga gaaaaagcta aggaattagg agtagatgtc tataattttg aaatgaaaga
    12361 acctttaata aatcctgaag atcagataag aatttttttg caatctcata aagaaattga
    12421 tggtatattt acaataaatg atatgatggc tctgagagtt attagtgtta tgaaagaact
    12481 ggggaaaata gcacctgatg attaccagat aattgggttt gatggtttaa aaacttctgt
    12541 cgatcaatct tatctagtgt ctacaatagt tcaagatatt ggtatgatgg caaaagaatc
    12601 tgttgcaatg atactgaaaa tgattaagcg agaagagatt ctagaaaaac gaatcgtaat
    12661 tcccacatat ttttggggag ataaaacaac aaaaaaaatt taaaaagcgc ttgacaatta
    12721 atgaaagcgc tgttataata taatcaacaa atgaaacgtt tcaaaaatag gctagaagct
    12781 tgtttaaaaa ataaataaaa aatgaaacgt ttcaaaaagg aggaaaatga tgcgtaaagg
    12841 tacaatgtta tctgttgttg cggggctatc gttagctata cttgcaggtt gtagtggagg
    12901 aactaactca aaacaagcga gttcttcaaa tgatattaaa gtctgggtac aattctctga
    12961 cgaaacaaat gaaggaaaag cttggcaaaa agttgttgat aactttaatc aatcaggaaa
    13021 aagtaagtac aaggttgtaa ctgagtatat tcctcgtagt ggtagtggtg gaggatatga
    13081 agacaaggtt aatgctgcta ttacgactaa tagtcttcca gatgttatta cccttgatgg
    13141 accaaatacg gcagcttatg caaaatctaa agtaattact ccgctagatg attatctaaa
    13201 agataataat atggatgatg ttttggacag tattaaacaa cagggaactt ataatgggaa
    13261 attctatgca tttggatttt ctgaatcgaa tgttggtgtt tattacaata aaaaaatgtt
    13321 caaagaggcc ggaattgcgg aatcagagct tccaacgcta gaaaagccat ggacatggga
    13381 cgaatttaat acgattgcta aaaaattgaa agatcattat aacaaaccag caattgattt
    13441 tcgtattaat tcaaacgatg aaatgttgcc atatgcttat atgccgttga tttggtcaaa
    13501 taatggttct gtcgtaaacg aagatggaac aaaggcagaa ggatacttca actccaaaga
    13561 gagtgtagaa gcagttcaat tcattcaaaa tcttgtaaaa gaaggctata caactgttag
    13621 tccagtcgaa aaaggttttg aaacaggaga gtatccaatg cttttgagtg gttcttggac
    13681 gattgctgac atgaatacaa actacaaaga tattgatttt ggtatccttc cttacccagt
    13741 atctagtaag acgaaaaaat tagtatcccc ttcaggtagt tggcaattag ctgtgacgac
    13801 aaaatctgat aaaaaagagg ccgcatctga atttgttaaa tttgctacaa atacagaatc
    13861 aagtgaaatt attagcttgg ggaattcggt ccttccaatt cgtaaatcta caattgaaaa
    13921 tatcaaagat aaagtatccg aaccaatgcg tttcttgatg gaacaaaatt caaaaacagc
    13981 tcatgctcgc ccagttgttg tagcatatcc tcaggtttct cgagcttttc aacaagcaat
    14041 gcaagatatt agctattatg aagaaaatcc aaatgtgcaa aaagtcttgg atactcgtac
    14101 aaaagaaatg caaactgcta ttgatcagtc actcaaataa tctgtaaaaa agaaggtgga
    14161 aggaaaatgt ttggaactac cttccccttt cttgttaata gcctagtttg atatatatga
    14221 ttaaaggaga tggatatgag taaagaaact gttgtggata caaaaagacg tgaaaaaata
    14281 aaggataaca tattaggtta tagtttttta gctccagctt taattttatt aggtatcttt
    14341 ttagtaattc cagttggaat ggtcatttat tacgctttta cagattatta tttgttgaca
    14401 ccagatgaaa gaaaatttgt tggacttgaa aattttattc gattaacaaa agatccgatt
    14461 ttcttaaaga gcttcttgaa tactttgaaa tttgttgttt ggattattcc agttcaattg
    14521 ggagcggcct taggaatggc tttgattgtc aataaaaagc gaaaaggaaa tatgtttttt
    14581 aaagtggctt tttttgctcc agttgtcatg tccttggtag ttatttctat tctttggctt
    14641 tatcttttaa atccaaatag tggcttattg aatgctattt taaataaggt aggtattgct
    14701 tctcaacctt tcttgactag tcctaaacaa gctatgtatg caattgtttt tgtttctgct
    14761 tggcagggtg caggttatca gatgctttta tttttaggag gaatgcagaa tattccacaa
    14821 gatgtctatg aagctgctga attagatgga ttctcaaaat gggctcagtt tcgttatatc
    14881 acgatgcccc tactaaaacc aacagccctg tttgtattgt taacaacttt aatttctgct
    14941 tttaagctga ttgtacaacc aatggttatg acgcaaggtg ggccattaaa ctcaacaatt
    15001 actatggtgt actatattta tcaacaaggt tttactgatc gtcttgtagg atattctagc
    15061 tcaatcgctt tagtatttac aacgttaatt ggtatgatta acttagtaca acgtcgcgtt
    15121 ctgaaggagg atgactaaga tgaaacgatt taaaccaaca acaatcttag aatatattct
    15181 gttaacttta ttggcaggac tcttcctttt tcctatggtt tggatggtag tttcagctat
    15241 gaagccagaa gcggatgttt ataaaaattt gactagttgg caagccttct taccaagttt
    15301 aaatcccgct gattggttta aaccttatca ggaagtattt gagcgcttta gtatttttac
    15361 atatctaggg aacagcattt tttatgctgg aacgtttgct attggttcta ttattgtcaa
    15421 tgcactggcc ggtttcgctt ttgcaaaagt caatttttca ggtaagaaaa ttttatttgg
    15481 tttcttactt gctttactta ttattccagt ggaaactgtg ttaattccac aatttaccat
    15541 tatcaattcc ttaggtttgg tcaataatcg tcttgcagtt attattccag gattggcgag
    15601 tgtatttaat atttacttat ttaggaattt ctttattgca attccagaag agattcttga
    15661 gtctgcaaag atggacggag caagtatcgt tagaattttc tttagaatta tgcttccaat
    15721 gtctaaacct gcagttgcta cagttggtgt tttatcattt atttcaagct ggaatgatta
    15781 tatctggcca ttgatggttt tgacagattc ttctaaattt tcaatgcagg ttgcaattac
    15841 aactattaat acaactcaac cagtttatat caatcaggta atggctgtat taactatttc
    15901 aacgattccg ttgattttgg tctatgtagt cgctcagaaa tatattgttc aaggtctggg
    15961 tggttccgga actggaataa aataggatat acttatgata aataaaacat ttacagtaga
    16021 aaaagccaat cgttttatag cagaaaataa acatctcgtt aatactcaat ataagcctga
    16081 agaacatttt tcagctgaga ttggttggat caatgatcca aatggatttg tctattttcg
    16141 tggagaatac catctctttt atcaattcta tccatatgat agtgtttggg ggcctatgca
    16201 ctggggacat gctaaaagta aggacttggt gacttgggag cacttgccag tggcacttgc
    16261 tcctgatcaa gattatgacc gaaatggttg tttctcaggc tctgccattg tcaaggatga
    16321 tcgcctctgg ctcatgtaca ctgggcatat cgaagaaaaa accggtgtcc gccaagtgca
    16381 aaatatggca ttttcagatg acgggattca ctttgaaaag atttcccaaa atccagttgc
    16441 aactggatca gacttgccag atgagttgat tgctgctgat ttccgtgatc caaaactctt
    16501 tgaaaaagat ggacgctatt actccgtagt agctgccaaa cacaagaata atgtgggctg
    16561 tatcgttcta ctagggtccg ataacctagt agaatggcag ttcgaatcca tctttttaaa
    16621 aggggtagaa caccaaggct ttatgtggga atgcccagat tacttcgagt tagatgggaa
    16681 agattgcctt attatgtcac ccatgcgtta tcagcgtgag ggagactcat atcataacat
    16741 caactcatcg cttttgttca cgggtaaggt agattgggga gaaaaatgtt ttatcccaga
    16801 atcagttcaa gaaattgatc atggccaaga cttctatgcg cctcaaacat tgttggacga
    16861 tcaaaatcgt cgtatcctga ttgcttggat gcagacatgg gggcgtaccc ttccaaccca
    16921 tgaccaagaa cacaagtggg catgtgccat gactttacct agaattctaa gattggaaga
    16981 tggcaaacta agacaattcc ctgttaaaaa aggccaatat caaatccaaa tagataaaga
    17041 ttgtcattac cacttaggaa atgatacaga ttatcttgaa tttggttatg acagtaatgt
    17101 gcagcaagtt tacattgatc gtagccatct tattcaaaaa attctaggtg aagaagaaca
    17161 ggacactagt cgacggtatg tagatattga agctaaagaa ttggaagttg ttctagataa
    17221 aaattccatc gagatttttg tcaatcaagg tgaagcaagc ttgactgcaa cttattactt
    17281 aacggtgcca gctgagctat cacgaattga ttaaaaatta agttatttct cctaaagaaa
    17341 aagttctctt tctaaaatag tggaaagagg actttttgtg ttttgggtat ataagcttag
    17401 tttatggtat ttgtaaaatt ggtgttggat tatgatttaa actagttttc taaagaattt
    17461 gaaaaaaatt ttatttaagc aaaaaaagcc ctatattata agacttttcc tgttgtattt
    17521 atatgccccc tacagggatc gaacctgtga cccacggatt aagagtccgc tgctctgcca
    17581 gctgagctaa ggaggcaaag aaaaaagctg tattggtgcc gaaacttcac ggtttgtatt
    17641 gaacccgcgc aattaagcag gtgggcaact cgctctaact gaagctgttt ccgtgtgaga
    17701 cggcctacat gctgttagaa gacttttgtt tccctaataa tacaaaaaat agtcggtcaa
    17761 cacttaagtg tgaagtcgta caccacagcg tttctatatt tatatgatac cactttttta
    17821 aaaaaaatca agaggaaagt gcaatttttt gaaaaggatt tcagattttt cgcaaatggt
    17881 cgatagcttc ctttctttga gccaaagccc gttcatattt accagtatct tctgcttgga
    17941 aatagtgatg attacgaatt ttttctggca gatagtcttg ctttacccaa tttccaggat
    18001 agttgtgtgg atagagatag tcttgggcat tccccagttc cttgcttcca ctgtagtgcc
    18061 catcacgtag gtgtcgcgga ataggcaagt gccctgatgt tttgaggtca gcaagtgcct
    18121 tatccatagc tacataggct gagttggatt ttggagaaag ggccaaatca atcacgacat
    18181 tggcaatgag aatgcgggct tcggggaaac caatcctttg tgcagcatcc agagcagtca
    18241 cggtatgaat ctgggcctca ggattggcta agccgatatc ttcataggcg ataacagtca
    18301 agcgacgagc gagactaggc agatccccag cctcaatcaa gcgggcagta tagtggagac
    18361 tggcatccac atctgagcca cgaatagact tttgcagggc agatagaaca tcatagtgac
    18421 cgtctccatc cttgtccata gtgatgtagc ttctctgaag actattttcc atgatgtcta
    18481 aggtgatgtg gcgaatgccc tcgtcattct caggggtaga tagaacagcc aagtccagtg
    18541 agttaaaggc agagcgaagg tctccgtttg tagaggttgc gatgaaatcc agcgcatcct
    18601 catctagttc tattggaaaa tcaaaaccac gttcagggtt acttagagct atctgcaggg
    18661 cctctttgac gtcttggtta gacagaggtt ccaactcgaa aatttgaaca cggctacgaa
    18721 tggcaggagt gacagagaag aaaggatttt cagtcgttgc tccaatcatg atgaccagtc
    18781 cactttccaa gagaggcaag aggaagtctt gcttggtctt atctagtcga tgaatttcgt
    18841 ctagcaatag gacgagacca ccagaaaatt tagcttcttc cgagatttct tgcagtcgct
    18901 ttttactatc aactgtcgca ttgaaagttc gaaaggcata cttggtcgtt ccagcgatgg
    18961 cagaggcaat actggttttg ccgattcccg gagggccata tagaatcatg gaggacaggc
    19021 ggttggcttc caccatgcgg cggatgattt ttccaggtcc gaccagatgc tcctgaccga
    19081 tgacctggtc gatggtttta gggcgcatgc gaagcgcgag attgtctggc atagcagtcc
    19141 tttctaacgt ggatttgagt agaatgactc atctactata tcttactatg tccattctag
    19201 cctattagtt gtgatatttc aatggttttg taataatcag ggagtgagat agaatctttt
    19261 ttactattta atttaatgag gagaggtatc agcatgagag atttgatttt ccttaaagct
    19321 caaaatagga tagttgagcc taaagaagtg gaagtgctga cttgagaaat aatattgctg
    19381 aatgtcattg tatgaactat aatgaaaaga gaggtgataa gcaatggaaa tgatggacca
    19441 agtcaggaaa ttttgatttt tacaaaacaa attcgtcatt ggattcttag tgatcaagtt
    19501 atttcaggga aaagaaaact tttcttccgg gaagatactc caaaagagat tttagatttg
    19561 tacgaaaaca ttaaatctaa acttgatttt gcttaccaag aagttcattc taataatggg
    19621 ttgaaaaaat atgaaaaata gaataattga tgtttttgaa gtagtaaatc gcctccttgt
    19681 aataactgtt gaaaatcctg atttcgaaga cttgagagtt aatcatactc aatgaaaatc
    19741 aaagagcaaa ctaggaaact agccgcaggc tgtacttgag tacggtaagg cgacgttgac
    19801 gtggtttgaa tttgattttc gaagagtatc agtttgtaaa aattggagat aaaaaatata
    19861 gagtacgcag tgttcctatg attcattcaa ctccgcctca atctgtctta gatcgagata
    19921 cttttacaat tgactataca gatgatgaat tgctcgataa agaagcagtt tttactactc
    19981 attagaaaaa taggtatgaa taaattggct tcccttagaa ccacatctag gggcttttat
    20041 gtataataga ataataagta tcactccttt acaatacgtg taacacgtgt tataatggtg
    20101 ttgtcaggag gtaaaagcgc tatgcctatg acacaaaaag agatggttaa actccttacg
    20161 gcccatggtt gataaagact agaggcggta aaggttccca tattaaaatc gagaagcaag
    20221 gggaaagacc tatcacaatc cctcatggtg agctgaataa gtacactgaa agagggataa
    20281 gaaagcaagc tgggttgtaa aattcagtcc ctgctttttg atatggaggt agtgaaatgt
    20341 tagttacgta tccagcttta ttttattatg acgacacaga cggaacagaa gcgacttatt
    20401 ttgtccattt cccagatttt gaatactcag ctacacaagg agaggggatt tctgaggctt
    20461 tggctatggg gtcggagtgg ctagggataa ctgttgcaga tttgatagag agtgatggag
    20521 agttacctca gccatcagat atcaatagct tgtctttaat tgataatgat ccttttaaag
    20581 atgatgaaga tttcgtgtca acctatgacc ttgataaatc ttttatttct atggtatctg
    20641 ttgatgtatc agaataccta ggaagtcagg aacccattaa aaagactttg accataccaa
    20701 aatgggcaga taagttggga cgagaaatgg gacttaactt ttctcagact ttgacagacg
    20761 ctattgcaga taagaaagtt caagcctaag attaagcgtg gtatcgtggt aatagtcaat
    20821 aaaaaagcac gtccacttgt gctagttact cgcctattga ttttatagat ttattagccc
    20881 tttcgagggc tttttatatt gatttttatg agaaatgaag aaatcagact tttaagaaaa
    20941 tcactgatac caagggttta aatgaggtaa tatggtataa ttaggacata aaataatttt
    21001 gtggtaagat ggtagtatct attttagcat atttccgagc aatcggggcg attaaagagt
    21061 cgcatagaaa gaggacaaaa tggcaacata cggattttta gatgttttag aggaagagtt
    21121 ggacaagaac tttccctttg actttgagat tagctgggac aaacgcaacc atgcggtaga
    21181 agtgagtttt ctattggaag cgcaaaatgc tgcaggtgtg gagatggtgg atgaagacgg
    21241 agaggtttca tcagatgaca ttctttttga ggaagcggtc cttttctaca atcctgccaa
    21301 gtcaaccgtc aatgcagaag actatttaac ggttatccct tatctaccta aaaaaggatt
    21361 ttctcgcgag tttttagctt attttgccct tttcctcaaa gatactgcgg aggttgggct
    21421 agataccctc atggactttt tggaagatcc agaagcagag gaatttgtta tggaatggaa
    21481 tcaagaagtc tttgaagaag gaaaagttgg cttggaagag ggagaatttt atccttatcc
    21541 aagatactag gagttggttg gaggtgttat gaagaaaatt gggacttatt tggtttatgt
    21601 gctagctgtt gtctttatta tgctagcttt tgcttgtgga acaatcgcat ttgcagagtt
    21661 ggggtattcc gcagttttag cctttacttt tggttatgcc ttcgctcttc taagcatgta
    21721 tttaatcttt attcttcatg agctgggtca tgctttttgt ggctacttga caggctatcg
    21781 gctggtggct tttggattag gacattttat tttgaccaaa aagtcaggca ggtttcatct
    21841 tagtagaaca gccattctga aaaatgttgg tgctcaatac attggtttaa aagaggatga
    21901 aagcgatcaa agaatcatcc tgatgctttc aggaggcttg atggttcatc tcggcttgat
    21961 attattggcg atagtgtttg gctttttgac aagaagctgg tattttgcag ggacttggat
    22021 ttttcttaat ttatctttct tcctaaataa cattttgcca gtcgacatca ccgatggagc
    22081 aaaaatttgg gaattactac aacaccctga aaataccaaa tacgcctacc tggtattgag
    22141 acattctgct caaactttgc tggctcctca agaatatgat ttgaaagact ttgttcaagc
    22201 agttcctgag gatgcacgag ggagttttgc ggatggtgta ttaggtatgc aaggtgaagt
    22261 ttccattttg gaagggaagg aagaagtagc taaacagcag tttcaagcat tacttgagag
    22321 gacaactact ccgatgatgc agacagttgc ccaactatcc ctgcttcata tcgccttgtt
    22381 ggaaggagat tttgagcaag cggagcaata tgctagtatt cgacaggtca aatcgtttct
    22441 gtctctcaaa ctgtccaatc ttcaagtgat acaagcctgg tatcaattaa aggtgaagaa
    22501 agatgtagat cgaactcgta aggctctcaa gattgctaga cagaaaatgg atagtagtcg
    22561 aatgttgagg gacgagaaac gctattatga aaacttgtta gcagagctgg aaaaggaaat
    22621 gttagaagga actgaagatg gaactagaaa tttctgattt ccaaggttgc aagattgccc
    22681 tcttttgtgg ggataagcta ctgacgattt tgcgtgatga caaggacgat atcccttgtc
    22741 ccaacatgtg ggagttgcca ggtggtggcc gtgaagggga cgaaagccct tttgaatgcg
    22801 ctcggcgtga agtttatgag gaactgggaa ttcatttaga tgaagactgt ctgctttgga
    22861 gcaagattta tcctagcgta atttttaaag gcaagaaatc ggtctttatg gttggtcagc
    22921 taagacaaga acaatttgac aatatcatct tcggagatga aggacagggc tatcagctga
    22981 tgaatgttga ggaatttctt agttccagtc aagttgtgcc tcagttgcaa gagagattaa
    23041 aagattattt aaaagtaagt gattagaaag gatggttcag ttaaatttct aaactgaacc
    23101 cgccctaaac actgtgccaa aaagataaac ttctcttaga cacaagcgtc ttcagagaat
    23161 ttcctatttt ggttttgtgt tttacgggct tggtatctta atgatggaaa catggcaaga
    23221 gttaaaagtt acagtgaagc gtgagggaga ggagttggtt tccaatctct tgattgagct
    23281 gggagcgcaa ggtgttgcga ttgaagacag tatggactat gtgggaaatg ttgaccgctt
    23341 cggcgagatt ttcccagagg tcgagcagca agaagaaatc gtagtgacag cctactaccc
    23401 tgacacggtg gatgtgacag tggttgaggc ggacttgcag gctcgcatat cagaattgac
    23461 ggattttatg gatttgggag agttaaaaat aggtacgact gccttggctg aggaagactg
    23521 ggcagataac tggaagaaat actatgagcc agctcgtatc actcatgatt tgaccatcgt
    23581 tccctcttgg acagactatg aggcgactgc gggagaaaaa attatcaagc tggatcctgg
    23641 catggctttt ggtacgggaa cccacccaac taccaagatg agcatttttg ccttggaaca
    23701 ggttcttcgt ggtggcgaaa cggtgctaga tgtgggaact ggttcagggg ttctctctat
    23761 tgccagctcg cttctggggg ctaaagaaat tttcgcctat gacctggatg atgtggcagt
    23821 tcgtgtggct caggaaaata ttgagctcaa ccctggaatg gaaaatatcc atgtagcggc
    23881 aggcgatttg cttaaaggcg tggagattga agcagatgtc atcgtggcaa acatcttggc
    23941 ggatatcctc attcatctga cagaggatgc ttatcgcttg gttaaggatg aaggttacct
    24001 gatcatgagt ggcattatca aggataagtg ggacatggtg cgcgagttgg ctgaatcagc
    24061 tggatttttc ctcgaaactc acatggttca aggggaatgg aatgcctgtg tctttaagaa
    24121 aaccaaggat atctctggtg tgattggagg ctagcatgca gcagtatttt gtaaaaggca
    24181 gtgctatctc tcctgtcact atcgagaaca aggaaaccag taagcatatg tttcaggtta
    24241 tgcgcttgaa agaagaggat gaggttacct tagtctttga tgatggcatc aagcgcttgg
    24301 cgcgcgtgct ggatatggaa aatcgtcagt ttgagttggt ccaagaatta aatgacaatg
    24361 tggaactacc agttcaagtg accatcgcat ctggatttcc caagggagac aagctggagt
    24421 tcatcgctca aaaagtaacc gaactgggtg ctagccaaat ctgggccttt cctgcagact
    24481 ggtcagttgc caagtgggat ggcaagaaat tgggtaaaaa agttgaaaaa ctagaaaaaa
    24541 ttgcccttgg agcagccgag caaagcaagc gtaatattgt accaagtatt aaacttttcg
    24601 agaaaaaagc agattttcta actcagctgg accagtttga ctctatcata gtagcctatg
    24661 aagaatcagg taaagaagga gaagccgctg cgcttctgca agcagtcact ggtcttgaaa
    24721 caggagccaa actgctcttt atctttggtc cagaaggcgg tctctcacct gcagaaatcg
    24781 aaagttttga agctaaggga gccgttttgg taggcctagg tcctcgtatt ttgcgagcag
    24841 aaacagcacc gctttacgcc ttatcagccc ttagtgtttt agtagaatta gagaaataag
    24901 aggaagaaaa tggaacaaaa acaccgttca gaatttccag agaaggaact ctgggactta
    24961 acagccctat accaagaccg tgaggatttc ttgcgtgcaa tcgagaaagc tcgcgaagac
    25021 atcaaccagt ttagccgtga ttacaagggc aatcttcaca cttttgagga tttcgagaag
    25081 gcctttgcgg aattggaaca gatctacatt cagatgagcc atattggcaa ctatgctttt
    25141 atgcctcaga cgacggacta tagcaatgac gaatttgcca atattgccca agctgggatg
    25201 gaatttgaaa cagctgccag cgtagccttg accttctttg acgatgcctt ggtggcagca
    25261 gacgaggaag tcttggaccg tttgggtaaa ttgccacatt taacagctgc cattcgtcag
    25321 gctaaaatca aaaaagccca ctacttaggg gcagatgtgg agaaggcctt gacaaatctc
    25381 ggtgaagttt tctatagtcc gcaggacatt tatactaaga tgcgagctgg ggattttgaa
    25441 atggctgact ttgaagccca tggcaagacc tataaaaaca gctttgtcac ctatgagaat
    25501 ttctaccaaa atcacgagga tgctgaggtt cgtgagaaat ccttccgttc cttctcagag
    25561 ggacttcgta agcaccaaaa tacggctgca gcagcctatc tggctcaggt caagtctgaa
    25621 aaactcttgg ctgatatgaa gggatatgac tctgtctttg actatcttct agctgaacaa
    25681 gaagtggacc gtgtcatgtt tgatcgccag attgacctca tcatgaagga ctttgcacca
    25741 gtcgctcaga gatacctcaa gcatgttgcc aaggtaaatg gtcttgaaaa gatgaccttt
    25801 gcagactgga aattggactt ggacagcgcc ctcaatcctg aagtgactat tgacgatgcc
    25861 tatgatttgg tcatgaagtc ggtagaacct ttggggcaag aatattgtca ggaagttgct
    25921 cgttaccaag aagagcgctg ggtggacttt gctgctaaca gtggcaagga ttccggtggt
    25981 tatgcagcgg acccatatcg cgtacaccct tatgtactca tgagctggac aggccgtttg
    26041 agcgatgtct ataccttgat tcatgaaatc gggcattctg gtcaattcat cttttcagac
    26101 aatcaccaaa gctatttcaa cgcccacatg tcgacctatt atgttgaagc accgtcgacc
    26161 ttcaatgaat tgctactcag tgattactta gagaaccagt ctaatgaccc acgtcaaaaa
    26221 cgcttcgctc tggctcatcg cttgacagac acctacttcc ataatttcat cacccacctc
    26281 ttggaagccg ccttccagcg taaggtgtat acattgattg aagaaggaga aaccttcgga
    26341 gcaagcaaac tcaacagcat tatgaaggaa gttttgacag atttttgggg cgatgccatt
    26401 gaaatcgacg acgatgcagc tttgacttgg atgcgccaag ctcactacta tatgggcttg
    26461 tatagttaca cttactctgc tggtcttgtc atctcgacag ctggttacct tcatcttaaa
    26521 aactcagaaa ctggagctga agactggctc aatctcctca aatcaggtgg tagcaagaca
    26581 ccacttgagt cagccatgat tatcggtgct gatatttcaa cagacaaacc actccgtgat
    26641 accatccaat tcttgtctga cacagttgac cagattatcg cctacagtgc tgagttgggg
    26701 gagtaagggg atagagaggt tgttatagaa tgggtatgga cagttatttg cttaaaagtc
    26761 catgtttaaa tcccccattc cttttcgagg aattctttgc ccttctctgt aatggtaagt
    26821 gaacgtggcg tttgtgcagg gatgaccaat tgtttttcac tgaaaaattc taaaagagca
    26881 ttgccgagag ctccgccgac atgattttta cgttcgctcc aatccaaaca tttagggcaa
    26941 aatttccgtt ttttcttttt caattcatcc gtatcaatgt gtaattttct ttggaaataa
    27001 gacttcccag cttcagtgag ttggaagtct ttttctgatt cgctgaggag attttcttgc
    27061 aagagataat tggtaatgga aatgccaagc tcaccagcaa tatggtcata gcaggtgcga
    27121 gcgaccttta attccttttt gtgaatgtgt tgtttataac ttttgacatc acgctgagga
    27181 gagtagaagc tgagaaattc cagcatttct gcaatggcag cactttttaa agaataataa
    27241 tgaaaacgtc cataggtttg tagagtggtt acctgcgctt cggtaagtaa tttgaggtga
    27301 tagctgacag tatgttgctt gattttggta aagctggcaa tttcgttaac cgtgtgagct
    27361 tttccatcca ttagaatatc taaaatgtgc atccgagaag ggtctgataa gagttttgtg
    27421 atgatgaaaa tatctggttt cataaaaatt ttctccaaat ttcatatatc gatgattttc
    27481 tatcttttat tatactataa ttaaagcaca agaaaaatag attttaaaaa tgttttacta
    27541 gagaatattt taaattttat tgtctgagtt taaatggagg taaaattaca aaagtaattg
    27601 cagcagtatc cacagttgaa ggacgttaat cttaagatta cattctcaac attttttcaa
    27661 aagtgagatg aattaacaaa gtatccaaca tgctctattt gtgggggaaa gaaagagtga
    27721 agaagttaag tgttaaaaat ctaaaaaagc aatatggttc ttatgaagct gtcaagggaa
    27781 ttagctttga attgggagac ggagagtgtt tgggtatctt gggaatcaac ggtgctggca
    27841 aaacatccac tttaaagatg atttactcac tgacctcaat ttcctcagga gagattgata
    27901 tcttggggca aaatattgaa accaatcgtc gtaagagtaa atcttgtctg ggtattgtag
    27961 ggcaggagga tatgctggac atgaccttga atgtttatga taatcttttt gctcacggtc
    28021 tatgttatgg tatctcatct gtcgaactta ggaagagaat cgattctctc ttggattttg
    28081 ttcaactgag caaacatgcg caaaagatgg tgaatcagct gtcgggtggg atgcgacgac
    28141 gtcttgtctt ggcaagagct ctcatcaatc ggcctgatat tatcatttta gatgaaccga
    28201 cagttggttt agacattcaa tcccgcaata ttatttggga taaacttttg gaattgaagg
    28261 aattaggtgt ttctatcatt attacttccc actatatgaa tgagattgaa tatttgacag
    28321 atagggtgct gatgctccac caagggacta tcaaagaaga aggaactgta gaagacttgc
    28381 tcatcaagta tgatgctgac aaccttgaga cgcttttttg ggggttgact gggacagaga
    28441 aggaggactt gcatgtttaa gttatcattt cactccatcg gacacgttgt ggtacgcaac
    28501 tacatgagtt ttagaaattt atttaaaatt tcaattgtcc ccaaccttat cgaccccctc
    28561 ttttatcttt tagcaatggg atttggagtt ggtgcttatt tgacgcatgt taacggtatg
    28621 ctctaccgtg attttgtcat tacaggttta attgctgcga ctgccatgtc tgcggccacc
    28681 gcagaaacaa cggtcaatgc ctttatccag tataagattg aaaagactta tgatgctatg
    28741 ttgatgacgc caatcaatac gaatgatatt gtggtaggtc aggctatctg ggcaggtatt
    28801 cgtgcagtga ttttcggtgg gattttttgg ctgatttcca tgcttatcac agcgcatttt
    28861 catgtcttga tgttattgat tcctctgatt ttatttatag tgggttattt gtttggtgtt
    28921 ttgggactaa tctttaccta cttggcgccg tctagggaat ttctgaatta ctacaatgtt
    28981 ttggtaatcc gtcctcttta tatgttttca gataccttct ttcccattac ttccttgccc
    29041 ccaatacttg gtgatttgac ttggttttct cccttgtatc acgctacccg catgattcgt
    29101 attatatggg gaggtgaggt gacaggtttg tatcttcatc ttatctggtt gatagccttg
    29161 gcgctcttga taacggtgct tcctatgtat atgttacatc gtagatatta tagatagtct
    29221 aattatttgt gatgttgtag tcatattcta atttatacta aacgttattc gaatttggac
    29281 aggtatggga actgtgccta tcaatattgt aatttatgga agttgaaata gtacggttca
    29341 gtttttaaat attgttagaa attgttttaa attccctaat caatttgtat agtttttatt
    29401 tcactttatt ataactagtt tttcgcaatt tttgagacag gaatgtgatt tttgtgataa
    29461 ggttctatca ttacaagttt atttgttgta atatggaata aatcatttat atatcttttc
    29521 agaaatatgc tgtttctctg aatataaatg tctttttctt tttaacttaa ttttacaaat
    29581 tggtaaggtc atttaagact gcctttttga acagttgcta gaaatgtaga ggtattgacc
    29641 atgtatcaag atttactaag aaaaatagca gaagaaaaac caaattataa ccaggaggaa
    29701 atccagtggt tgcttgatca tttgggagat ccttctccag aaattcgtga tgatcttgtt
    29761 tttacaagct ttgctagagg gattcaggaa gagctattta cacaggagca atttcatttc
    29821 attgctgagg tggtcttagc tgatggaggg ttagataaag agattgataa ggtaggcttg
    29881 tcaacacttg aacgttcttt tagggcactt gtttatgcaa atctcttgtc tgtagatgct
    29941 aaccagcaat cggtttttta tcagggatta caatcagaaa ttcgtaatgt ccttttaaat
    30001 caaggcttgc actatctttc aaaagaaaag gatacaacag gtttctcaag tcagtatggt
    30061 tgggttcacg cttttgcaca tggagccgat ttactgaaag aggtggtttg tcatccagac
    30121 tttcctaaaa acagagttca tgaagtattt gatatacttg gccaactatt taaaagaatg
    30181 tcgattcgct ttacagatga tgaggattgg cgtttagcaa gagtgatcta tgaacctatt
    30241 ttacaaggga agttagcgca agaacaagta gcttcttgga taaaaactgt tgattttccg
    30301 atagaagaaa gggaggattt ttacaaattt tccaacttca gaacctgtct gttggaagtc
    30361 tatgtccaac ttgaccagag aaatagttta caagatgagt tgaaagaagc tatccagtct
    30421 tttcaatact agagattagc taatagttct atgattttca aaaaatttcc aatcaatttt
    30481 cttgaaaccc tttcctactt ttgatagact agtatctagt ttttgaaaaa aggagaaaga
    30541 aaatgaaaaa atttgttgct gagttaatcg gtacgttcat gcttgtattc gtcgggacag
    30601 gagctgttgt ttttggaaat ggtcttgatg gccttggtca ccttggaatc gcctttgcct
    30661 ttggtttggc aatcgtggtg gcagcctact caatcggaac tgtttcaggt gctcacttga
    30721 atccggctgt ttcgattgct atgtttgtaa acaaacgttt gtcatcttca gaacttgtaa
    30781 actacatcct tggtcaggtt gttggagctt tcatcgcttc tggcgcagtc ttcttcctct
    30841 tgggtaattc aggtatgtca actgctagtc ttggtgaaaa tgccttggca aacggtgtca
    30901 ctgtctttgg tggtttcttg tttgaagtca tcgcaacttt cttgtttgtc ttagttatca
    30961 tgactgtgac ttcagaaagt aagggcaatg gcgcgattgc tggtttggta atcggtttgt
    31021 cattgatggc gatgattctt gtcggattga agattactgg actttcagta aacccagctc
    31081 gtagcttggc accagctgtc ttggtaggcg gcgcagccct tcaacaagtt tggattttca
    31141 tccttgcacc aatcgctggt ggagttcttg cagcccttgt tgcaaaaaat ttccttggaa
    31201 cagaagaata attgaaactc aaaaagcctt gctcctcatc ttgaggaaca gggctttttc
    31261 gtatgatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgtc ctaggtatgg
    31321 ttactgactt cgtcagttct atctgcaacc tcaaaacagt gttttaagct gacttcgtca
    31381 gttctatctg caacctcaaa cactgctttg agtaacctgc ggctaacttc ctagtttgct
    31441 ctttgatttt cattgagtat gactttagcg gttgtcaatt ttctctggat aaaggtcgtg
    31501 ttggaagagg cgttgttctg ccaagccctc atacttagtt ccttgcttac cgtagttata
    31561 gtaggggtcg attgaaatgc caccgcgcgg agtgaatttt ccccagactt ctaaatagcg
    31621 agggtctagc aagttgacca agtctttccc gatggtgttg atacagtttt cgtggaaatc
    31681 tccgtgattt cggtagctaa atagatatag tttgagggat tttgactcga cacagagctt
    31741 gtcaggaatg taggaaatat gaatcgtcgc aaagtctggc tgagcagtga tttgtcccag
    31801 cagagacata tcgaggatat ggtgacgaat gccctgttcc ttagcgattt ctctagtaat
    31861 ttgaatttcg aggtgatgac gttggccgta ggcaaaggtg acagcttcga ctgtttcata
    31921 gtgttgcatg gcccagaaaa ggcaggttgt tgaatcttga ccaccactaa agacgaccaa
    31981 ggctgattga cgtttcatag tactccttcc aaaatgggaa atgttcagag cacgcaaaaa
    32041 gctcccatta gggagctaaa aaataccaaa tcgagttttt ttagcgatgg catatcccaa
    32101 acatcgtaat attctactt
//
LOCUS       DAVBNZ010000020        31122 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000020 DAVBNZ010000000
VERSION     DAVBNZ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31122
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.020"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..567
                     /locus_tag="VQ860_000981"
     CDS             <1..567
                     /locus_tag="VQ860_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3119423.1"
                     /translation="DSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLVTELSHLG
                     YNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPKLSYLSTLIRYEELYAINPN
                     QARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTTSAADVLH
                     ELLFGEWSQVEKEMLRVGEKRLNELLEK"
     gene            595..1752
                     /locus_tag="VQ860_000982"
     CDS             595..1752
                     /locus_tag="VQ860_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119424.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISKKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYS
                     DYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQV
                     VIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            2571..2930
                     /locus_tag="VQ860_000983"
     CDS             2571..2930
                     /locus_tag="VQ860_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119425.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIVE
                     VNQAQPLSREFCEKYMG"
     gene            3006..3304
                     /locus_tag="VQ860_000984"
                     /pseudo
     CDS             3006..3304
                     /locus_tag="VQ860_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480038.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
     gene            3291..5155
                     /locus_tag="VQ860_000985"
                     /pseudo
     CDS             3291..5155
                     /locus_tag="VQ860_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(5200..6052)
                     /locus_tag="VQ860_000986"
                     /pseudo
     CDS             complement(5200..6052)
                     /locus_tag="VQ860_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            6134..6205
                     /locus_tag="VQ860_000987"
     CDS             6134..6205
                     /locus_tag="VQ860_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET3119426.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
     gene            6309..7178
                     /locus_tag="VQ860_000988"
     CDS             6309..7178
                     /locus_tag="VQ860_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="HET3119427.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFHDEVKEINYLLQQYRDCLVTDS
                     GKDYTVIGKYDNL"
     gene            7165..7887
                     /locus_tag="VQ860_000989"
     CDS             7165..7887
                     /locus_tag="VQ860_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3119428.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            7884..8414
                     /locus_tag="VQ860_000990"
     CDS             7884..8414
                     /locus_tag="VQ860_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119429.1"
                     /translation="MIINTLGPTATDCFYAINRIKLKVDVIVLYDSFDSIVNCFDKLK
                     GQYILLPVAFESSIKNYSWKDFNFEYHKRIEIVDSFHSFTKGMVLIENCNYKINRAII
                     QPATEILMLNYLKKKSMDLRIDFTHSKVMANKKFLEEGYRFSIVSQETIINNDDIIIC
                     ETFSPEMIWCLYRVKG"
     gene            8418..9512
                     /locus_tag="VQ860_000991"
     CDS             8418..9512
                     /locus_tag="VQ860_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119430.1"
                     /translation="MFSEIIKKYDIVTLKDSGFLRGDWFIGSALMAHDYESLKEGIYF
                     YPQETIWTRILDLEYINPYWEIYNQTYNFLLVNKQDSLAMNFLTSLLREIEVISSKTL
                     DFVVITSNEHLIRNLIDRDYYIITKEIPFFIENSKVGNYFKIFVKNGGQFIPIIDCTE
                     FKIQSKKYFEININKFYLKLLDYFLHGEIPEKFKFFGNTSNFNIESLFLEFIDSQENI
                     RVVSLLDCLIQLSSKNIEISGNYKGHTVKKILKKFALYSVITKLDITKVNHLLRNDYI
                     YFLMKEIDNITKKYPKLIQKYPRDILSDRYGITNEVYRYLIGENLHIKINHKLDEVRY
                     FTDIPFIDTSLSIEEFDKIVSKILKIKVGG"
     gene            9515..10186
                     /locus_tag="VQ860_000992"
     CDS             9515..10186
                     /locus_tag="VQ860_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119431.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDVELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
     gene            10188..11216
                     /gene="galE"
                     /locus_tag="VQ860_000993"
     CDS             10188..11216
                     /gene="galE"
                     /locus_tag="VQ860_000993"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3119432.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVIES
                     IKQISKKSRNLHFYKIDLKNEEKLENVFKRHNFDGVIHFAGYKAVGESVVEPLKYYEN
                     NLLSTINILKLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYIEV
                     LLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLN
                     IFGVDYSTPDGTCIRDYVHVNDLADGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEI
                     LHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQ
                     KHPNGYDD"
     gene            11240..12484
                     /locus_tag="VQ860_000994"
     CDS             11240..12484
                     /locus_tag="VQ860_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HET3119433.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVGSITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQVLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMFVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            12534..12893
                     /locus_tag="VQ860_000995"
     CDS             12534..12893
                     /locus_tag="VQ860_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3119434.1"
                     /translation="MISRIGDIMFDFANNTFLAGLNPTSLSVVAIYQSLESMIGVLFN
                     LFGGVIADSFKRKKIIITTNILCGIACITLSFISQEKWLVYAIVITNVILAFMSAFSG
                     PSYKAFTKEIVKKDSIS"
     gene            12945..13697
                     /locus_tag="VQ860_000996"
     CDS             12945..13697
                     /locus_tag="VQ860_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3119435.1"
                     /translation="MIAIFLYKLLGIHGVLLLDGLSFLIAASLIFFITPVNEEVDTKE
                     NMTIRGIFDDLKIGFTYVYSHKQILTIIALSALVNFFLAAYNLLLPYSNQMFGSISSG
                     LYGTFLTAEAIGGFIGAILSGFINKSLSSKRLMLFLAYSGLMLMLTAPIYYMFRNVII
                     LAFTPALFSLFLSIFNIQFFSIVQRDVDNEFLGRVFGIIFTVAILFMPLGTVFFSVVL
                     NPNNTFNFFIIGVSITILSLIFSTLLKRYDRS"
     gene            14377..14598
                     /locus_tag="VQ860_000997"
     CDS             14377..14598
                     /locus_tag="VQ860_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3119436.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            15046..15348
                     /locus_tag="VQ860_000998"
                     /pseudo
     CDS             15046..15348
                     /locus_tag="VQ860_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            15504..16733
                     /locus_tag="VQ860_000999"
     CDS             15504..16733
                     /locus_tag="VQ860_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3119437.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            16753..19449
                     /gene="ppc"
                     /locus_tag="VQ860_001000"
     CDS             16753..19449
                     /gene="ppc"
                     /locus_tag="VQ860_001000"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET3119438.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    19532..19749
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            19862..20866
                     /locus_tag="VQ860_001001"
     CDS             19862..20866
                     /locus_tag="VQ860_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3119439.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            20935..21801
                     /locus_tag="VQ860_001002"
     CDS             20935..21801
                     /locus_tag="VQ860_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3119440.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            21798..22556
                     /locus_tag="VQ860_001003"
     CDS             21798..22556
                     /locus_tag="VQ860_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119441.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQVTIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            22646..24406
                     /gene="dnaG"
                     /locus_tag="VQ860_001004"
     CDS             22646..24406
                     /gene="dnaG"
                     /locus_tag="VQ860_001004"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET3119442.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKIIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            24409..25518
                     /gene="rpoD"
                     /locus_tag="VQ860_001005"
     CDS             24409..25518
                     /gene="rpoD"
                     /locus_tag="VQ860_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET3119443.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            25532..25861
                     /locus_tag="VQ860_001006"
     CDS             25532..25861
                     /locus_tag="VQ860_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3119444.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            25976..27019
                     /gene="cpoA"
                     /locus_tag="VQ860_001007"
     CDS             25976..27019
                     /gene="cpoA"
                     /locus_tag="VQ860_001007"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET3119445.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPATLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            27035..28360
                     /locus_tag="VQ860_001008"
     CDS             27035..28360
                     /locus_tag="VQ860_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3119446.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAISEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            28391..28567
                     /locus_tag="VQ860_001009"
     CDS             28391..28567
                     /locus_tag="VQ860_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3119447.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            28626..28760
                     /locus_tag="VQ860_001010"
     CDS             28626..28760
                     /locus_tag="VQ860_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET3119448.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            28824..30134
                     /gene="obgE"
                     /locus_tag="VQ860_001011"
     CDS             28824..30134
                     /gene="obgE"
                     /locus_tag="VQ860_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET3119449.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEETYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            30144..30302
                     /locus_tag="VQ860_001012"
     CDS             30144..30302
                     /locus_tag="VQ860_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119450.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT        10386 a         4729 c         6286 g         9721 t
ORIGIN      
        1 gatagttttc gttctcagca tccacactat ttagaactgc agcaagaata tggcaaagat
       61 agtgtagaat acaccaaaga ttttgcaggt aaaatggtag agtctttagt aacagaattg
      121 agtcatttgg gatacaatct tttgatagag ggaactttac gaacagttga tgttccaaag
      181 aaaacagcac aactcttgaa aaataaggga tatgaagtac aattagcctt gattgcgaca
      241 aagcctaagc tgtcctatct gagcactctt attcgatacg aagaactgta cgctatcaat
      301 ccaaatcaag cacgcgcaac accaaaagaa catcatgatt tcattgtaaa tcatctagtt
      361 gataatacac gacaattgga agaactagct atttttgaaa gaattcaaat ttaccaacga
      421 gatagaagtt gtgtatatga ttcaaaagaa aatacaactt cagcagcaga tgttcttcat
      481 gagttattgt ttggagagtg gagtcaggta gaaaaggaga tgttgagggt aggggaaaag
      541 agacttaatg aattacttga aaaataaaca attgatattt ttaggagagt agaaatgaga
      601 gggtttaata acaagataaa gtctgtttat caagaactaa caaattccaa agagaaattc
      661 ggtagctttc acaagacttt aattcatttg catacacctg tttcttatga ttacaagcta
      721 ttttctaatt ggactgcaac gaaatataga aaaattactg aagatgaact atatgatata
      781 ttttttgaaa ataagaaaat aaaagttgat aagacaattt tttttagtaa ttttgataag
      841 gttgtttttt ctagttcaaa agaatatatt agttttctta tgttagcaga ggcaatcata
      901 aaaaatggaa tagaaatagt tgtagtaact gatcataata ctaccaaagg tattaaaaag
      961 ttacaaatgg cagtctcaat cataatgaaa aattatccga tttatgatat acatcctcat
     1021 attttacatg gagtagaaat tagtgcagca gataaattgc atattgtatg tatatatgat
     1081 tatgaacaag aatcatgggt taatcaatgg ttaagtgaaa atattataag taagaaagat
     1141 ggaagttatc aacattcact gactataatg aaggatttca ataatcaaaa aatagttaac
     1201 tatattgctc atttcaatag ttatgacatt ttgaaaaaag gttctcactt atcaggtgca
     1261 tataaacgaa aaattttttc taaagaaaat acacgatttt tggagtttaa tattaactcg
     1321 aaagaatctt cgcaacaact tgatattctc tataaagaag ttggtgtatt aagtttggga
     1381 caaaaagttg tagccatgct tgatttttta ttagcatata gtgactattc taaagacttc
     1441 agaccattga ttattgatca gcctgaagac aatctagaca atcgttatat ttacaggcat
     1501 ttagttcagc agtttagaga tgtgaaagct caacgtcaaa ttattttagc aacacataat
     1561 gctacaattg taacaaattc tatgacagat caagttgtta ttatggagtc agatggagtt
     1621 aacggatgga ttgaatcaca gggatatgtt agtgaaaaat atataaaaaa tcatatcatc
     1681 aatcaattag agggaggaaa agattccttc aagcataaaa tgtctatata tgagacggct
     1741 ttatcagagt agagtcagaa aaagtaggtt agaaatttag cctacttttt tctttgttcg
     1801 acaggcatag tgtacatctg aggtccaagt cctctgtgga tatttgctgc agatgaaacc
     1861 aatagcgact cctaagcctg aatatcgtga tgtagggggg ataggaagga attagcgaaa
     1921 tcaaggttct acaaacagaa tcgtgacttg aagccatata tagcggatga ggaactctaa
     1981 aatccaaata ggtgtcgtaa cctatatacg taaattacga gagtaaacta ggaaagatgt
     2041 acggcttatt ccgtgagcgt ttaggacgta gtacaacgaa tcatgggagt cagctgaaca
     2101 catagtattg aagaaatttc tgtaatggaa atggagcgaa gaagtgaaca attaaatgaa
     2161 tacctctcta attaaatttg tcaattctaa ttcctggtat gaaaagacag tgacctaaaa
     2221 atgtaaacga tgggagctga tcataaatat aggacggtac atgcagtggt gttagagatt
     2281 agtccctact tgatttgtga taacttcccc aactttcttc tgctatactt ttctcaactt
     2341 ttaaaaatcc aactaagaat tttacctggg agtttggggg cgtagccacc aagttatctt
     2401 atggttagct gtcaaaactg gaaggttttg gttagctggc gatatgattt tttgggtatt
     2461 gtgaccacaa tgcctgagct cgcaaagacc gaacaaggac tttaagaaat ttcccgtatg
     2521 acacacgggg tcggggttta cccgagaaag gatgaaagtg aggaaaagag atgtctgaac
     2581 agtaccgtga cattcgaaaa gaggtaaatc taaccgcaga tgagctaaaa cagattgaaa
     2641 aaatgatgga ggttgataat tatcgtcact tttcaccatt cgtcagggat aaaattttga
     2701 tgactgatga caaacagtta gctgccaaag aatggttttc cctttggcag tctcaaaagt
     2761 ttgaacagat cagtcgagat gtgcatttgg ttttgattat cgcaagagag aatcatcaag
     2821 tgactcaaga gcacgtctca atcttattga cttgtgttca agaattaatt gtagaagtca
     2881 atcaagctca gccactcagt cgtgaattct gtgaaaaata tatgggatag gagactgcta
     2941 tggtttatcg ttatcgtact aatctaaaaa aatatttcta actgattcag aattgaatta
     3001 attaaatgat cgtattacta agagtcactg tcaaaatttc tcagtctacg ccagaaaagt
     3061 tttgcttaat cccaatatgt catttgtcac gattaacact gatacttatg aacagttagt
     3121 gtttgaattg aggaggattg gaaataacat caatcaaatt gcgcgtgcga ttaatcaaag
     3181 ccatctgatt tctcaggacc aattacaaga attgagtaaa ggagtcggag agttaattaa
     3241 ggaagtggac aaagaatttc aagtggaggt gaaaagactg aaggagtttc atggtagtta
     3301 ctaaatactt tgcgacgcac ggaaaaaaat atcgtaggcg tttgattaaa tatatcctca
     3361 atccagataa aacagataat ctaaaattag tatctgattt tggcatgagt aattacttag
     3421 attttcctag ccatgcagaa atggtagaaa tgtacaatgt taactttact aataacgaca
     3481 agttgtacga gtccagaaat gaccgacaag aaaaacacca acaaactatt catgcccatc
     3541 atctcatcca atcattttct cctgaagata atctgacacc tgaagaaatt aaccgcattg
     3601 gttatgagac catgatggaa ttgacaggag gtcgttttaa gtttatcgta gcaactcaca
     3661 cagacaaaga tcatgttcat aatcacatcc taattaacgc tattgaccgc aattcagata
     3721 aaaagttgat atggaactat gccttggaac gaaacctccg tatgatttca gaccgtattt
     3781 ctaaaatggc tggtgcaaaa attattgaga aacgttattc ctatcgagat tataaaaaat
     3841 ataaggaatc tagtcataaa tttgaattga aacaacgtct ttattttttg cttcagcaat
     3901 ctaaatcgtt tgatgatttt ttagagaaag caaagcagtt gcatgttcag attgatttta
     3961 gtcaaaagca tagccgtttt ttgatgacag atagaacgat gataaaacca attcgaggtc
     4021 gccaacttag taaacgagat ttatatgatg aagacttttt taaaacatat tttgccaaac
     4081 aagagattga aagtcattta gaatttttgt tgaaccgtgt caattcttta gaagagttaa
     4141 taacaaaagc aaaagaattg aatctaacca ttgacttaaa acaaaaaaat gtaactttta
     4201 tcctggaaga agataatcaa aagataagtt tgggtcataa aaaataagtg ataagaaatt
     4261 atatgatgtc aaattttttc aagattattt taaaaataag gaagtcgttg cttcagaagg
     4321 attagagaat ttataggaac agtaccatgc tttccaagaa gaacgagata aggataaagt
     4381 atccactgaa gagattgagg aagcctttga gatatttaag gaaaagagag atgctgttcg
     4441 tgaatttgaa gtggaacttg cagagaacca aatagagaag ctagttgatg agggaattta
     4501 tatcaaagtg tcttttggta ttaagcagag tggtcttatt ttcattccca attatcaatt
     4561 ggatactatg gaagaagaca atcagaaaaa atataaagtc tacattcgag aaacgtcttc
     4621 ttactttgtc tataataaag aaaacatgga taataattgt ttcatcaagg gtaggacctt
     4681 aatcagacaa ttgagcaacg atagccaaaa actcccctat agacgaccaa ctttaaaaag
     4741 tcttcaagag aagatttcta aaattaatct tatgattgaa ctatctaaca cgaacaaaca
     4801 ataccaagaa atcaaagatg agcttgtatt agaaattgca gagattgata tgcagctaga
     4861 agaaacccaa gaaaaaatcg ccaccttaaa caagatggcg gaagtcctta tcaatttgaa
     4921 gagtgaagat catgagacta gaaaattagc taagtatgat tttgaccaaa tgaacatgac
     4981 ggaatcaata atgttagatc gactcaatac ggatatttta aaattacaac aggaacttgg
     5041 taatgaaatt aataaatatg aggagatagc tagaagattg gatttgtttg tgaaaattat
     5101 taataccaat aaatttacag ttctaaaatt tcacgagaat gccttactag aataatatta
     5161 tttacgacta attagttaaa agatagagaa taatttcatt tattttttat ttactagttt
     5221 attaaaatgg tcagtatagt gtaattttaa cttgtattct cctaaaatat cgagaacttg
     5281 tatagcttgt ttcattgttt caataccact acttaattga cgtttaaatt catagtaacc
     5341 ggttgcatag agaaaaactg tctgttcata aaagtttaat tcattctcta acaatccctt
     5401 tatctcatta attaaataag agcaattaga aaattcttct ttatctatgc tgagaatgaa
     5461 acaatttata gctagctgag tgacaatccg cttatttgtt ttatttagag atgagtaaat
     5521 ataattattt aacatttctt tagttaagta agaagtagga gttgtagtta attgttcgta
     5581 cacagttacc taataaaata atctcataat aaccccattt ttcaacttta aagagataat
     5641 ctgctagttg aagtaattca tcatctgatg gaatgattct tgaatccatt gtgtgtaaaa
     5701 tggattttac cattgttttt tcaaaagaat ctaaagtgta atttgaggaa tccgaaagta
     5761 gagattgtat attattgatg ttttgtaatg aatattgttt acggatatac tgtattaagt
     5821 tggcaaatga ctcagttttt gtatagtctt catcgtgtaa aataagaaac tcatccaaag
     5881 taatgtgtaa tttgtctaaa atattgatca gtcggataca tgatatctct gactctccac
     5941 gttcaaatcg ggatatttgc gattttgaaa gatgctcatc agcaacagag catagactga
     6001 tttgtttgcc tttacgaact tttctaagtg tgatgccaag ttttgatttc atagtttttc
     6061 ccattttccc aacaaaaagt taacttagtt ttatttattg tacaataaat aaaaattgaa
     6121 aggaagtcta aatatgaaga aaatttcaaa atttttccca attttgatgc tagtgatgga
     6181 cattatcatt attgttggtg gttaaatcac ttaggtgtac acctaagtct ttagagtatc
     6241 taaagactat acttactagc taaaacatat ttaagttaaa tcgtaaaatt ttagagagtg
     6301 gtgagacttt gaaacataaa aaagtattaa ttatagggta tggtataatg actcggggta
     6361 tattaaaaat cctgaaacag tcgaaaaaat ataatatata cctatatagt aggcatctaa
     6421 attcaacaat aaatggaata atatttatta gagaagatga attacctgat gctataaatc
     6481 aggttgattt tataatcact tgttttagta atcatattga aacggataat ttcattaatg
     6541 agtttttatt aaatatacaa tcacttcgta aaaccatagt aattgatttt acaacctcca
     6601 ggattgattg cgttgaaaaa tttaaaaaaa ctgttgaaat taaaggggga tactatatag
     6661 aggctccttt cacaggaggt aagttaggaa gtaatagtgg tcaactatca atttttttac
     6721 atattgatga aggtgtaaac tataataaaa aggagttaat ggaattatta aaattaattt
     6781 caaaaaaaat atactttttt gaaaagagta cggaaccaac aaaattcaag ttaatttata
     6841 actcgtgggg agcgtatttg ctttactcta ttaagctatt caacccttta cagtatgatt
     6901 tttcaccaaa gtctctagag gtagcgaata caatcgtatg taatgatggt tggatgagtt
     6961 tagtatgcaa ctccaaatta gaacagatca atgatcaaga ttttgatgac atacacttta
     7021 gagtagaata tatggtaaaa gatttagaat atgctaattt ttcagtcttt catgatgaag
     7081 tgaaagaaat aaattattta ttacagcaat atagggattg cttagtaact gatagtggaa
     7141 aagattatac ggtaatagga aagtatgata acttatagga atgacttgct gtctaaagaa
     7201 ttagatatac taatttcatt ttttaaaaaa tgcgaggtag gaaaaatttc actcgttatt
     7261 actggttcct tggcaagagg taatccaaga atcaaggatg ggaaattaga atcggatatt
     7321 gatattctag ttatagtaga cagtattcag caattaatta gtataaaaaa gactttagag
     7381 ggaaggtttc actttgtaca taaaatttct ttgatttttt gtttgaagga aagaataaat
     7441 cgaagtcgtt atcgtggaat tattaatagt attagaagtg tagataatct tttagtagat
     7501 aatctgcata taaaaaatca aataatagaa gctttagact cacctaccaa tattgtggag
     7561 cagactcgct ctatgattca ggaattttgt tattattcat caaaatattt aatttcaaag
     7621 aataattatt tggaattaaa actagaaaag tattggaagg agattgcaac attaaatcat
     7681 atcgataaaa agataaaaca cctagatttt gaaagaatat ttgctgtttt aaaagaacac
     7741 aaaatacaaa ttttggattc aagtgaatat tttttccaaa atgtaaaaac ttctgagaat
     7801 atttatttag agatgaggga tttagtatct ttggaaaatc aaggattaga ctttgaacat
     7861 tgtattttga gcttggggga aagatgataa taaatacatt aggaccaact gcaacagatt
     7921 gtttttatgc aataaatcgt ataaaattaa aagtagatgt gattgtactg tatgatagtt
     7981 ttgatagtat agttaattgc tttgataaat taaaagggca atatatatta ttacctgtag
     8041 ctttcgagag tagtattaaa aattatagtt ggaaagattt caactttgaa tatcataagc
     8101 ggattgaaat tgtggattct tttcactctt ttactaaggg aatggttcta atcgagaatt
     8161 gtaattataa aattaatagg gcgattatcc aacctgcaac tgagattttg atgttaaact
     8221 atttaaagaa aaaaagtatg gatctgagga tagattttac ccatagtaaa gttatggcaa
     8281 ataaaaaatt tctggaagaa ggttatcgtt tttcaatagt aagccaagaa acgataatta
     8341 ataatgatga tattattatt tgtgaaactt tctctccaga aatgatttgg tgcttatata
     8401 gagtgaaagg atagaaaatg ttttctgaaa ttattaagaa atatgatatt gttacactga
     8461 aagatagtgg ttttttgaga ggtgattggt tcataggttc agcgttaatg gctcatgact
     8521 atgaaagcct taaggaaggg atatatttct atccccagga aacaatttgg acaagaatct
     8581 tggatttaga atatataaat ccgtattggg aaatatataa tcaaacttat aatttcttat
     8641 tagttaataa acaagattca ttagcaatga attttttaac tagtcttcta agagaaatag
     8701 aagttatttc gtctaaaaca ttagattttg ttgttattac ttcaaacgaa cacctaatta
     8761 ggaatttaat tgatagagac tattatatta ttacaaaaga gattccattt tttattgaaa
     8821 actcaaaagt tggaaattat tttaaaattt ttgtgaaaaa tggaggacag tttattccta
     8881 taattgactg tacggaattt aagattcagt ctaagaaata ttttgagata aatattaata
     8941 aattctacct gaaacttttg gattactttc ttcatggaga gattccagaa aaatttaaat
     9001 tttttggaaa tacctctaat ttcaatatag aaagcttgtt tctagaattt attgatagcc
     9061 aagaaaatat tcgagtagtt tccttgttgg attgtcttat tcaattatcc tctaaaaata
     9121 ttgaaatttc aggaaattat aaagggcaca cagtgaaaaa aatactaaaa aaattcgctt
     9181 tatactcagt aattaccaaa cttgatataa cgaaagtaaa tcatttattg agaaatgatt
     9241 atatctactt tttaatgaag gaaattgaca atattactaa aaaatatcca aagttaattc
     9301 aaaagtaccc tagagatatc ttgagtgata ggtatggaat aacaaatgaa gtatatagat
     9361 acttaatcgg agagaattta catataaaaa ttaatcataa attagatgag gttagatatt
     9421 ttacagatat tccatttatt gatacttcac tttctattga agagtttgac aaaatagttt
     9481 ctaaaatatt aaaaattaaa gtgggagggt aactatgata agattaccaa ataaatttaa
     9541 aggtaataat ataactctag aagttaaact aaataaagca gttgatgcta gtgtattata
     9601 cccagatgtt aagtctctag atcaagaatt gtatcgacaa ctacaatcag tagaatcatt
     9661 ctatcttacc ttttctgata tgtattcaga aattaatgaa aataatgaaa tcttatatac
     9721 agaaataatc tttaagatac ctctttgtat tggagaagat tattttaatt ttccggttgt
     9781 atcatatgtt tcaaatccct attcgttaat aagaggattt tatctaggtt ttcataagga
     9841 attggactgt aactatgtat ttgatgatgt agagcttcat ttttttaggg aagggatttg
     9901 tgaatttaac ttcgaattta aaaatcaaaa ttcaatcatt acagcagaat taccaaggga
     9961 gtataactat cccttgatct tgtttaataa ttccaatctg gttaatcaat atggaaaata
    10021 tactttgtta gacatagaca aatataaatt agagtctaga aagatttttg aatttccaga
    10081 aatttctatc ggtaactttc ttggaagtga agcaaaatca aatagggtaa tttttagcca
    10141 agataaattt caaattaatg gcataaagaa tatggaggta aattagcatg aaatcattat
    10201 taataacagg tggagcagga tacataggat cacatacggt tttggacttg ttagataata
    10261 attatgaagt aacaatcatt gatgatttga gtaactctaa gaaaaaagtt attgagtcta
    10321 ttaagcagat atccaagaag agtagaaatc ttcattttta taaaattgat ttaaaaaatg
    10381 aagaaaaatt ggaaaatgtt tttaagagac ataattttga tggagtaatt cattttgcag
    10441 ggtataaagc tgttggagaa tccgtggttg aaccattgaa gtattatgaa aataatttat
    10501 tatcaactat aaatatttta aaactaatga aaaaatataa ggtatttaat tttgtgttta
    10561 gttcatcagc tactgtatac gaaagtactc ctatcatgcc attctatgag actaatccat
    10621 taaaagcttc aaacccgtat gggagaacaa aacagtatat agaagtactt ttaaatgatt
    10681 tgtttatttc gaattcaaat tggaaaattg tttgtctgag gtattttaat ccattgggtg
    10741 cacatgaaag tggtgattta ggagaggatc caaatggaat tccgaataat cttgttcctt
    10801 acattacaca agttgcaatt ggaaaattac catatttaaa tatattcgga gttgattaca
    10861 gtactcctga tgggacttgt ataagggact atgttcacgt taacgattta gcagacggac
    10921 acagaaaagc attagagtat atttttaata cagatgaagg tttatatgaa gtaatcaatt
    10981 taggaagtgg tgttggtttt agtgtatttg aaatcctaca cagcttagag agtgtcatag
    11041 gctcgtatat tccatataag ataacttcaa ggagagcagg agatatggac gtttcaattg
    11101 cagatatttc aaaagcagaa gagctactgg gatggaagcc aaggtatgat attatgaaaa
    11161 tgtgccaaga tacgtggaaa tggcaacaga aacatccaaa tggatatgat gactaataat
    11221 tgaaaggatt gggattaaca tgcatatagt attatttaga tattctgcac gggttgttaa
    11281 actaaaatat ctgtataaca gaaatgtagt aattattgca cctgaggttc aaagaaaaaa
    11341 atatgaagat tatctagctg aaggaaataa tctacctaag gtcatttttt tagaagattt
    11401 tattctacca aatatcatct tagaaattag aaggataagt caaaatacag aagttgggag
    11461 tattacaacc ttgagtgagg aagacatgga tatagtaggt tttttgaatg atcattttgt
    11521 agaaaaaaat actcactctg tgtctaattt attatttaaa gacaaatact tcatgcgttc
    11581 atttttagtt ggagtagtaa atcaaccgta ttttaggctt ttagaatcag aaaatgattt
    11641 acgtgttttt tggaataatt gtaaatcttc tgctgcaatt ttaaaaccta gaaatgaagc
    11701 aggaagtaat ggaataaaaa aagtttaccc taacgagaaa attgattcag tgtattttga
    11761 aaaaaactat attatagagg aatacattga tatcgataac atgataacat gtgatggtta
    11821 ttcaattgga agtgagatta agcgatttta tgttcacgaa tatgaggaac tattgttcaa
    11881 taccttaagt tctagtggat attatcttgt aaggactagt tcgttatata atgatagtga
    11941 aaaaattgaa tacatagaaa aagcattgga agaatgtcgc aaagttttga atgttttttc
    12001 tatcaattct gaaataaccc cttttcattt tgaatggttc cttgaattat caactggtaa
    12061 aatagtcttt tgtgaagttg gaaaaagatt tggaggggga gatattcccc agttaattga
    12121 ggatagtcat ggagttgatg taattaaaga atattgggat attttgacta attcacaagt
    12181 attgaaaaaa ataaattttt ctaaagtgat ttctagacct gctaatatct cagcaacgtt
    12241 tgctttatat agaaagcaag gtaaggttat cgaggtacct gatgaaaaag aattggcttg
    12301 ggcaaaaaaa gtgtacatat ttattaaacc aaatacttac tataaagtat ctgaaaatgt
    12361 agtcgaaaat tcaatgtttg tccaatttaa ttgcaaaaat agttgtgaat ttgagaaaag
    12421 gttagatgaa cttaagcaca tatcacaaaa gtttaaatat gtgattactg attcgggaga
    12481 ataaaatgat tagagaagaa catcacaata ttctatccat tgtagctagt aggatgatat
    12541 ctcgaatcgg agatatcatg tttgatttcg ccaataatac ctttcttgct ggtcttaatc
    12601 caacatctct atcagtggtt gcaatttatc aatcattaga aagtatgata ggtgttctat
    12661 ttaatttatt tggtggagtt attgcagata gtttcaagcg gaaaaaaatt attattacta
    12721 caaatatctt atgtggtatt gcttgcataa ctctttcatt tatatcccaa gaaaaatggt
    12781 tggtttatgc gatagtcata acaaatgtca ttttggcttt tatgagtgct ttttcagggc
    12841 catcatacaa agcttttacg aaagaaattg taaaaaagga cagtatatca taacttaatt
    12901 cattgctaga aacaacaagt actgtgatta aagtaacaat tcctatgatt gcaattttct
    12961 tatataagtt acttggaata catggtgtgt tattactaga tggattatcg tttttaattg
    13021 ctgcctcact aattttcttc attactcctg taaatgagga ggtggataca aaagagaata
    13081 tgacgataag aggaatcttt gatgatttaa aaataggatt tacgtatgta tatagtcata
    13141 aacaaattct cactataatt gccctttcag cacttgttaa ctttttccta gcagcctata
    13201 atttgttgct gccatacagt aatcaaatgt ttggaagtat ttcaagtggg ctatatggaa
    13261 cctttttaac agccgaagcg attggtggct ttattggtgc gatattaagt ggatttatca
    13321 ataaatcctt gtcaagcaaa cgtttaatgc tctttttagc atattcaggt ttgatgttaa
    13381 tgctaacagc gccgatctat tatatgttcc gcaacgtcat tattttagcc tttactccag
    13441 cattatttag tctatttctt tccattttta atatccaatt tttctctatt gttcaaagag
    13501 acgtagataa tgagtttctt ggcagagtat ttggaatcat ctttacggta gctattcttt
    13561 ttatgccact aggtactgtt tttttctcag tagttttaaa tcctaacaat acttttaatt
    13621 tttttattat tggtgtatct attacgatat tatcgctaat atttagcacg ctattgaaga
    13681 ggtatgatag aagttgatag atgataaaaa atagctgata tagagaattt agagcgcctt
    13741 tggaatatat ttttggaatt taatcaatca cagttgaatg tgaagggcaa tcctttttag
    13801 aagaatacaa tcaagatacc attatgctat ttctttagtt cagttaaaat attgagaagt
    13861 attactttta ttgaaaaagc atcacaaagg actccaatta atttttaatg atttttctaa
    13921 tctaattttg tggttattga caaataaagt ctagttaatt gctttgaaat ccatggagtg
    13981 gtctatatac atctgttaat gcaacggaaa attttattga taagtagggg gtggctatta
    14041 ttcagctttt aggttctgaa agtaagagat tcacattaga aatatcatgt tgaccatttt
    14101 tcaatttgct ggttagtagt aatctggaca tcattaatcc cttccttaac aaaattatgt
    14161 gacttttgtt accggattac tgctgatttt ttaatagctt ataacatctt tagacggtta
    14221 atagattttg accgtctttc ttaatattgt cttacctata atagatatgc ttatgagata
    14281 tgtttaataa attaatttta gttcaaaatg tccagtttgg acactttgaa tgatttctta
    14341 gttttatata ttatactttt ctcaggagaa agctagatgt acagacgttt gagagatttg
    14401 agggaagatc acgatttgac ccaaaaacaa atagctaaaa tactttcgtt tacagactca
    14461 gcttatgcta aaattgaacg gggtgagcat acgttaacag cagatatatt ggtaactctc
    14521 tcaaactttt acgatgtcag tacagactac ctattgggat tgacggattt tcctgataaa
    14581 attcgcttta gaaaataatc tcctcaattt catagagtgt gaaaatgcga agattttttt
    14641 tatttgttct ttgacaattg aatagtccaa aatggtactt tcctcatttg tggagcagat
    14701 ttgaatggtt cgccatgata agagcgatat taaaaccatc aataaaatag agcgatactt
    14761 tatatgccat gatacaaatg atatacaatg atacttctga ccgttcaggc tgccaccgta
    14821 aaagagcagc aagtgaaatt cttatgatga cttcatcagt catgccatgt tgaatgtgtg
    14881 agtttgttag ataaacgcaa ttaatcctca aaaggttccc cgaacctttt gagttctaca
    14941 gacgcatcac gtggagtgtg taagcttgtt gctaaaagcg taaaaacctt ggaacgaaag
    15001 gaataataga cttcctgcga aacaaaaata taatacaata aaactatgaa tgatgaagca
    15061 agtaaacaat tgagcgatag ccgtttcaag atccttgtag gtgttcagcg cacgactttt
    15121 gaagagatgt tagcggtgtt aaaaacagct tatcaacgta aacgcgcaaa aggtggacga
    15181 aaaagcaaat taagcctaga cgatctcctt atggtaacta ttcaatacat gcgagaatag
    15241 cgcacttatg aacaaattgc ggctgatttt ggcattcacg aaagcaacat aattagtcgg
    15301 agtcaatgga ttgaagcaac tcttattcaa aatggtttta cgatttcaaa ttctgcctta
    15361 attctgtaaa aacagtaaaa ttcgaaggat tgtaaggtaa gagttttttt ctttctgaaa
    15421 aaatggtata atagcaatca aaactagaaa ataaaacgga atttggaaca gatttgtctg
    15481 tatcctagta gagtggtgat actatgaaga ttagtaagag gcacttatta aattattcca
    15541 tcttgattcc ctacttgctt ttatctattt tgggcttgat tgtggtctat tcgaccacca
    15601 gtgctatttt aattgaagaa ggcaagagcg ccttgcagtt ggttcgaaac caaggaatct
    15661 tttggattgt tagtttgata ctgattgcct taatttataa attgagacta gattttttga
    15721 gaaatgagcg actaatcatt ttagttatat taatagaaat gcttttattg ttcttggctc
    15781 gttttattgg tatttcagta aacggggcat acggttggat ttcggttgca ggagtaacta
    15841 ttcagccagc tgagtactta aaaatcatta ttatttggta tttagctcac cgattctcca
    15901 aacagcaaga agaaatagct acttatgatt ttcaagtttt gactcaaaat caatggcttc
    15961 cccgtgcttt taatgattgg cgattcgttc tcctagttct gattggaagt ttgggaattt
    16021 tccctgattt aggaaatgcg actattttag tcttggtttc cttgattatg tatacagtta
    16081 gtggaatcgc ttatcgctgg ttttcaacca ttctggcgct cgtatctgcc acttctgtct
    16141 ttgtcttgac cactatcagc ctaatcggtg ttgagacctt ttcaaaaatt ccagtatttg
    16201 gctatgtagc caagcgcttt agtgcctttt ttaatccttt tgccgatcgt gctgatgcag
    16261 gtcaccagtt agctaattct tattttgcca tggtcaatgg cggttggttt ggtctaggtc
    16321 ttggaaactc gattgaaaaa cgaggttatt tgccagaagc tcatacagac tttgtctttt
    16381 ctatcgtgat tgaagaattt ggctttgttg gtgccagtct tattttagct ctcttgtttt
    16441 tcatgatttt gcggattatc ttggtcggta tccgagcgga gaatcctttc aatgccatgg
    16501 ttgcactcgg tgtcggaggg atgatgttgg ttcaggtatt tgtcaatatc ggagggattt
    16561 cgggcttgat tccatctaca ggagtgactt tccccttctt atcccagggt ggaaatagtc
    16621 ttctagtctt atcagtggca gtagcctttg tcttaaatat tgatgccagt gaaaaacgcg
    16681 ctaaattgta ccgagaattg gaaaatcaac caatgaacct tctgttgaag taggataaag
    16741 aaaggatagt ttatgtctct tcaaaaatta gaaaattata gtaataaaag tgttgtgcaa
    16801 gaagaagtct tgattctaac agaattactg gaagatatta ctaaaaatat gcttgcccca
    16861 gagacctttg aaaaaataat acagttgaaa gaattatcaa cgcaggaaga ttatcaaggt
    16921 ctaaaccgtc tagtgactag cttatcaaat gatgaaatgg tctatatttc acgctatttc
    16981 tctatcttgc ctcttttgat taatatttca gaggatgtgg atttagctta tgaaatcaat
    17041 catcaaaata atattgatca ggactattta ggtaaattat ctacaacgat taaattggta
    17101 gcagaaaagg aaaatgccgt tgagatccta gaacacttga atgttgtccc tgttttgaca
    17161 gcccatccaa cacaagtgca acgcaaaagt atgttggatt taacaaatca tattcatagt
    17221 cttttgcgta aataccgtga tgttaagttg gggttgatca ataaagataa atggtacaat
    17281 gatttgcgtc gttacatcga aattatcatg cagacagaca tgattcgtga gaaaaaatta
    17341 aaagtgacta acgaaatcac gaatgctatg gaatattata acagctcctt tttgaaagct
    17401 gtacctcatt tgacgacgga gtataagcgc ttagcgcaag cgcatggtct gaatttaaaa
    17461 caggctaaac caatcaccat gggtatgtgg ataggtggtg accgtgatgg aaatccattt
    17521 gttacagcaa agaccttgaa gcagtctgca ctcactcagt gtgaagtcat catgaactac
    17581 tatgataaaa agatttacca actttatcgt gaattttctc tttcaactag cattgtcaac
    17641 gtcagcaagc aagtcagaga aatggctcgt caatccaagg ataactcgat ttaccgcgaa
    17701 aaagagcttt accgtcgtgc cttgtttgat attcaatcaa aaattcaggc aactaaaacc
    17761 tatctgattg aggatgaaga agttgggact cgttatgaaa ccgccaatga tttctacaag
    17821 gatttgattg ccattcgaga ttctctacta gaaaataagg gcgagtcctt gatttcaggt
    17881 gattttgtgg aattattgca ggcagtagag atatttggtt tttacttagc atcaattgat
    17941 atgcgacaag actctagcgt ctatgaagcc tgtgtggcag aactcttgaa atcagcagga
    18001 attcattctc gttatagcga gttgagcgaa gaagaaaagt gtgaccttct cttgaaagaa
    18061 ttagaagaag atccccgaat tctttctgcg actcacgcag aaaaatcaga attattagca
    18121 aaagaattag ctatttttaa gacggctcgt gttttgaaag ataagttggg agatgatgtc
    18181 atccgtcaga ccatcatttc acatgcaacc aacctttctg atatgctaga attagctatt
    18241 ctgttaaaag aagtaggact ggtggatacg gaaagggcgc gtgttcagat tgttcccctt
    18301 tttgaaacaa ttgaagactt ggatcattca gaggaaacaa tgagaaaata tctttctctt
    18361 agccttgcca aaaaatggat tgactcacga aataactacc aagaaatcat gcttggctac
    18421 tctgacagta ataaagatgg cggttacttg tcatcatgtt ggaccctcta caaggctcaa
    18481 caacaattga ctgctattgg agatgaattt ggcgttaagg ttaccttctt ccatggtcgt
    18541 ggtggtactg tcggtcgtgg tggtgggcca acctatgaag ccattacatc tcaaccgctc
    18601 aagtctatca aggatcgtat ccgtttgacg gagcagggtg aagtaattgg gaataaatac
    18661 ggtaacaaag acgccgctta ctataacctt gaaatgctag tatcggcagc tattaaccgt
    18721 atgattactc agaagaagag cgataccaat accccaaatc gttatgaagc cattatggat
    18781 caagtagtgg accgtagtta cgatatctac cgtgatttgg tctttggtaa tgagcatttc
    18841 tatgattatt tcttcgagtc aagtccaatc aaggctattt caagttttaa tattggttct
    18901 cgtccagccg ctcgtaagac tattactgaa atcggtggtt tgcgtgccat cccttgggta
    18961 ttctcatggt cacagagtcg tgttatgttc cctggatggt acggggttgg ttcaagcttc
    19021 aaggaattta tcaataaaaa tccagagaat attgctatct tacgagatat gtaccaaaat
    19081 tggcctttct tccaatcgct tctttcaaat gttgatatgg ttttgtcaaa atcaaatatg
    19141 aatattgctt ttgaatatgc taaactttgt gaagacgagc aagttaaggc catctatgag
    19201 attattttaa atgaatggca agttactaag aacgttatct tggctattga aggacatgac
    19261 gaactcttag ctgacaatcc atatctaaaa gctagtctgg attaccgtat gccttacttt
    19321 aatattctca actatattca gttagagttg attaaacgcc aacgtcgtgg agaattgtcc
    19381 agtgatcaag aacgattgat tcatatcacc atcaacggaa ttgcgacagg attgcgtaat
    19441 tcaggttgat aattttcaag agtgaatgct aaaagtgaat atcaaaaaaa ttctaataga
    19501 ctattgacaa gtagtttaaa aatgatataa tttaaccatt cagaaaagta atcatacaaa
    19561 ctttttagag agtctgtggt agctgaaaac agataagtgg cgatgatgaa aattgggctg
    19621 aatgctattt agaatttgaa attataaaaa ttcggtaagc acaccttaca gtgcatctcg
    19681 ttattgcgag actgagcgat agggaaattc cctataattg aggtggtacc gcgcatcgac
    19741 gtcctcacac aagttttttg tgtgaggatt tttttgatgg aggttagtat ggaaagaaaa
    19801 cgatggcgtc gcttgtttag ataagtgaaa tatgttaaag gaaataaaaa ggagaaacag
    19861 aatgaaaaat aaacgtttaa ttggaattat tgctgcatta gcagtcttag tagcaggaag
    19921 cttgatttat tcttcaatga ataaatcaga agctcagaat aataaggatg agaagaaaat
    19981 aactaagatt ggtgtgcttc aatttgtgag ccatccatcc cttgatttga tttataaagg
    20041 gatccaagat ggacttgcag aagaaggata taaagatgat caagttaaaa ttgattttat
    20101 gaactcagaa ggtgaccaaa gtaaggttgc gacaatgagt aaacaattgg ttgcaaatgg
    20161 gaatgacctt gtggttggta tcgcaacacc agcagcccaa gggttggcta gtgcaacaaa
    20221 agacctaccg gttatcatgg ccgctattac agacccaatt ggtgctaact tggttaaaga
    20281 tttgaaaaaa ccaggtggca acattacagg ggtatctgac cacaatccag ctcaacaaca
    20341 agttgaactc atcaaggctc tgacaccgaa tgtgaaaaca atcggagctc tttactcaag
    20401 tagcgaagac aattcaaaaa cacaggtcga agaatttaag gcttatgctg aaaaagcagg
    20461 tctgacagtg gaaacatttg cagttccttc aacaaatgaa attgcctcaa ctgtcactgt
    20521 tatgactagc aaggtagatg ctatttgggt tccaattgat aacaccattg catcaggatt
    20581 tccaacggtt gtctctagca atcaaagttc taagaaacca atttatccca gtgcgacagc
    20641 tatggtagaa gtaggtggtt tggcatcagt tgtaattgac caacatgacc ttggtgtggc
    20701 aacaggtaaa atgattgtgc aagtcttgaa aggtgcaaaa ccagccgata ccccagtcaa
    20761 tgtcttttca actggtaagt cagtcatcaa taaaaaaata gcacaagaac taggtattac
    20821 tatccctgag tctgttctca aagaagcagg acaagtcatc gaataaataa ggtagggagg
    20881 aggagactct tcccattttt taaaaagatg aatatagaaa ggattaaata aaatatgatt
    20941 gtttccatta tttctcaagg atttgtctgg gctattctag gtctgggaat ctttatgaca
    21001 tttaggattt taaactttcc agatatgacg acagaaggtt ccttccctct tgggggagct
    21061 gttgctgtca ctttgataac caaaggcgtg aacccatttt tagcgacact tgttgctgta
    21121 ggagcaggtt gtttggctgg aatggcagca ggccttcttt atacaaaagg gaagatccca
    21181 accttgctct cagggatttt ggtgatgact tcttgtcact caatcatgct cttgattatg
    21241 ggacgtgcga atttaggcct gcttggaacc aagcaaattc aggatgtttt gccttttgat
    21301 tcggatttga atcaactctt gacaggtctc atctttgtga gtattgttat tgctctcatg
    21361 ctctttttct tggacactaa actcggacaa gcctatattg ctacagggga taatcctgat
    21421 atggctagaa gtttcgggat tcatactgga cgcatggagc tcatgggctt ggtcttatca
    21481 aatggtgtga ttgcccttgc aggtgccctc attgctcagc aagaaggtta tgccgatgtg
    21541 tctcgaggga tcggggttat cgttgtgggg cttgcaagtt tgattattgg agaagttatt
    21601 ttcaagagtt tgagcttggc agagcgtttg gttactatcg ttgtaggttc tatcgcttat
    21661 caatttttag tgtgggcagt tatcgcactt ggctttaata caagttacct tcgtttatac
    21721 agtgccttga ttttagcagt ctgcctcatg attccaacat ttaagcaaac aatcttgaaa
    21781 ggagccaagt taagcaaatg acagcaattg tagaattaaa aaatgcaacc aaaatcgtta
    21841 aaaatggctt tgatgaagaa aagattattt taaatgatgt ttccttagaa atttttgaac
    21901 gggactttat cacgattttg ggcggaaatg gtgctggaaa atcaaccctc tttaacacta
    21961 tagcagggac cttatcacta actagtggaa ctatccgtat tttaggtgaa gatctcacta
    22021 agttttcacc cgagaagcgt gccaagtacc tgtctcgtgt cttccaagat ccaaagatgg
    22081 ggacagctcc ccgtatgacg gtcgctgaaa atcttttaat cgccaagttt cgtggtgaaa
    22141 agcgtggatt gttaccacga cgcttgacta gctataagga tgaatttcag gtaaccattg
    22201 aaaaagtagg aaatggtctt gagaaacact tgaatacacc gattgagttc ttatcaggtg
    22261 gacaaagaca ggctttgagt ctcttgatgg caaccttgaa gcgacctgaa ttactcctgt
    22321 tagatgagca tactgctgcc ctggatccaa agactagtgt tgctttgatg gaattgacag
    22381 atgaatttgt taagaaagat cagctaacag cccttatgat tactcatcat atggaagatg
    22441 ctctcaaata cggcaatcgc ttgattgtca tgaaagaagg acggattatc caagatttaa
    22501 accaagaaga aaaagcaaaa atgaaaatct ctgattatta tcaactcttt gaataaagta
    22561 gggaaaatga gtgaaatagt ttactttttt tctgaaataa agtatactat atatagtata
    22621 ctatgataac atggaggtat tgtgtatggt tgacaaacaa gtcattgaag aaatcaaaaa
    22681 caatgccaac attgtggaag tcataggaga tgtgatttct ttacaaaagg caggacggaa
    22741 ctatctaggg ctctgtcctt ttcatggcga aaaaacacca tctttcaacg ttgtagagga
    22801 taagcagttt tatcactgtt tcggttgtgg tcgctcaggt gatgtcttta agttcatcga
    22861 ggagtaccaa ggggttccct ttatagaggc agtccaaatc ttaggtcagc gtgttggaat
    22921 tgaggttgaa aaaccgcttt atagtgagca gaagtcagcc tcacctcacc aagctcttta
    22981 tgatatgcac gaagatgcag ccaaatttta ccatgctatt ctcatgacaa cgactatggg
    23041 agaagaggcc agaaattacc tttatcagcg gggtttgaca gatgaagtgc ttaaacattt
    23101 ttggattggt ttagcacctc cagaacgaaa ctatctctat caacgtttgt ctgatcagta
    23161 tcgtgaagag gatttactgg attcaggcct gttttatctc tcggatgcca atcaatttgt
    23221 agacaccttt cacaatcgca ttatgtttcc cctgacaaat gaccaaggaa agatcattgc
    23281 cttctcaggt cgtatctggc aaaaaacgga ttcacaaact tctaagtata aaaacagccg
    23341 atcgactgca atttttaaca aaagttacga attatatcat atggataggg caaaaaaatc
    23401 ttctggaaaa gctagtgaga tttacctgat ggaaggattc atggatgtta ttgcagccta
    23461 tcgggttgga atcgaaaatg ctgtggcgtc gatgggaacg gccttgagtc gagagcatgt
    23521 tgagcatctg aaaaggttaa ccaagaaatt ggttcttgtt tacgatggag ataaggctgg
    23581 gcaagccgcg atattgaaag cattggatga aattggtgat atgcctgtgc aaatcgtcag
    23641 catgcctgat aacttggatc ctgatgagta tctacaaaaa aatggtccag aagacttggc
    23701 ctatctatta acgaaaactc gtattagtcc gattgagttc tacattcatc agtacaaacc
    23761 tgaaaacagt gaaaatctgc aggctcagat tgagtttatt gaaaaaatag ctcccttgat
    23821 tgttaaagaa aagtccatcg ctgctcaaaa cagctatatt catattttag ctgacagtct
    23881 ggcgtccttt gattatgccc agattgagca gattgttaat gagagtcgtc aggtgcaaag
    23941 gcagaatcgc atggaaagaa tttccagacc gacgccaatc accatgcctg tcaccaagca
    24001 gttatcggct attatgaggg cagaagccca tctactctat cggatgatgg aatcccctct
    24061 tgttttgaac gattaccgtt tgcgagaaga ctttgcattt gctacacctg aatttcaggt
    24121 cttatatgac ttgcttggcc agtatggaaa tcttcctcca gaagttttag cagagcagac
    24181 agaggaagtt gaaagagctt ggtaccaagt tttagctcag gatttgcctg ctgagatatc
    24241 gccgcaggaa cttagtgaag tagagatgac tcgaaacaag gctctcttga atcaggacaa
    24301 tatgagaatc aaaaagaagg tgcaggaagc tagccatgta ggagatacag atacagccct
    24361 agaagaattg gaacgtttaa tttcccaaaa gagaagaatg gagtaataat ggcaacaaaa
    24421 caaaaagaag taacaacatt tgacgtacag gtagcagaat ttatccgtaa tcataagcaa
    24481 aaagggacag caacagatga tgaaatcaat gcaagtttgg ttattccttt taccttggac
    24541 gctgatggga ttgaagatct cttgcaacgg attcaggatg caggaatttc tatcacagat
    24601 aacgaaggaa atccaagtgc gcgtgttctt agcaatgaag aagaaccaga actcagcgat
    24661 gaggacttga ttgggtcaac ttctgctaag gtcaatgacc ctgtccgtat gtacttgaaa
    24721 gaaatagggg tcgttcctct cttgaccaat gaagaggaga aagagttggc actggctgtt
    24781 gaagctggtg atatcgaagc caaacaacgt cttgcggaag ccaatcttcg tttggttgtt
    24841 tccattgcca aacgctatgt cggtcgtggt atgcagttcc ttgacttgat tcaagaagga
    24901 aatatgggct tgatgaaggc ggttgacaag tttgactatt ctaaagggtt caagttttca
    24961 acttatgcaa cttggtggat tcgtcaggct atcactcgtg ctattgcgga ccaagctcgt
    25021 accatccgta tcccagttca catggttgaa actatcaata aattggttcg tgaacagcgg
    25081 aatctccttc aagaattggg gcaagatccg acaccagaac agattgctga acgaatggat
    25141 atgacacctg ataaggttcg tgaaatcttg aagattgccc aagaaccagt atctcttgaa
    25201 actcctatcg gtgaagagga cgatagccac ctcggagact ttatcgaaga tgaagtgatt
    25261 gaaaatccag tggattatac gactcgtatc gtcttgcgtg agcaattgga tgaaatctta
    25321 gatactctta cagaccgtga agaaaatgtt ctgcgtctac gttttggact agatgatgga
    25381 aaaatgcgca cacttgaaga tgtggggaaa gtctttaacg taactcgtga gcgtatccgt
    25441 cagattgaag caaaggcttt gagaaaacta cgccaaccaa gtcgtagcaa accgcttcgt
    25501 gattttattg aagactaaga gtgaggaaaa tatggcttat acagaagagc aaattgaaaa
    25561 catcaaaaca cggattttaa cagccttgga agaagtcatc gaccctgagt tgggaatcga
    25621 tattgtcaat cttggtttga tctatgagat tcgttttgac ggtgacacag ggcaaacaga
    25681 gattgacatg actttgacaa ctatgggttg tcccttagca gaccttttga cagaccagat
    25741 ttatgatgct atgatagagg ttccagaagt aacggatact gaggttaaat tagtctggta
    25801 tccagcctgg acagttgaaa aaatgagtcg ctatgcccgc attgccctag gcattaagta
    25861 aacatataaa agcatgtgag agactgttgg aaaagcgagg aaatttcccc acttttcctc
    25921 tagtctctcc tttcttttgc tgattttatt caaagaaaat gatataatag tagttatgga
    25981 gaaaaagaaa ttacgcatca atatgttgag ttcaagtgag aaagtagcag gacagggagt
    26041 ttcaggtgct taccgtgaat tagttcgtct tcttcaccgt gctgccaagg accaattgat
    26101 tgttacagaa aatcttccaa tcgaggcaga tgtgactcac tttcatacga ttgattttcc
    26161 ctattattta tcaaccttcc aaaagaaacg ctcagggaga aagattggct atgtgcattt
    26221 cttgccagct acacttgagg gaagtttgaa aattccattt ttcttaaagg gaattgtgaa
    26281 acgctatgta ttttcttttt acaaccggat ggagcacttg gttgtggtca atcctatgtt
    26341 tattgaggat ttggtagcag ctggtattcc acgtgaaaaa gtgacctata ttcctaactt
    26401 tgtcaacaag gaaaaatggc atcctctacc acaagaagag gtagttagac tgcgcacaga
    26461 tcttggtctt agtgacaatc agtttatcgt agtaggtgct gggcaagttc agaaacgtaa
    26521 agggattgat gactttatcc gtctggctga ggaattgcct cagattacct ttatctgggc
    26581 tggtggcttc tcttttggtg gtatgacaga tggttatgaa cactataaga aaattatgga
    26641 aaatccccct aaaaatttga tttttccagg cattgtatcg ccagagcgga tgcgcgaatt
    26701 gtatgctcta gcggatcttt tcttgttgcc tagttacaat gagctctttc ctatgactat
    26761 tttagaagct gcgagttgtg aggctcctat tatgttgcgt gatttagatc tctataaggt
    26821 gattttggag ggaaattatc gggcgacagc gggtagagaa gagatgaaag aggctatttt
    26881 ggaatatcaa gcaaatcctg ctaccttaaa agatctcaaa gaaaaggcta agaatatttc
    26941 cagagagtat tctgaagagc atctgttaca aatctggttg gacttttatg agaaacaagc
    27001 cgctttaggg agaaagtaaa aagtgaggta atctatgcga attggtttat ttacagatac
    27061 ctattttcct caggtttctg gtgttgcgac cagtattcga accttgaaaa cagaacttga
    27121 aaagcaggga catgctgttt ttatctttac gacgacagat aaggatgtca atcgctacga
    27181 agattggcaa attatccgca ttccaagtgt tcctttcttt gcttttaagg atcgtcgctt
    27241 tgcctaccga ggttttagca aggcacttga aattgctaaa cagtatcagc tagatattat
    27301 ccatactcag acagaatttt ctcttggcct gttggggatt tggattgcgc gtgaattgaa
    27361 aattccagtc atccatacct atcacaccca gtatgaagac tatgtccatt atattgctaa
    27421 ggggatgttg atccggccga gtatggtcaa gtatctggtt agaggtttcc tgcatgatgt
    27481 ggatggggtt atttgcccta gtgagattgt ccgtgacttg ctatctgatt ataaggtcaa
    27541 ggttgaaaaa cgggtcattc ctactggaat tgaattagcc aagtttgagc gtccggaaat
    27601 caagcaggaa aatttgaaag aactgcgtag taaactaggg attcaagatg gtgaaaagac
    27661 gttgcttagt ctttcgagaa tctcctatga aaaaaatatt caagcagttt tagtagcctt
    27721 tgctgatgtt ctgaaagagg aagacaaggt taaactggta gtagctgggg atggccctta
    27781 tctgaatgac ctcaaagagc aagcccagaa cctagagatt caagactcag tcatctttac
    27841 agggatgatt gctcctagtg agacggctct ttactataaa gcggcggatt tcttcatttc
    27901 ggcatcgaca agcgaaacgc aaggtttgac ctacttggaa agcttagcca gtggaacacc
    27961 tgtcattgct cacggaaatc cttatttgaa caacctcatc agtgataaaa tgtttggaac
    28021 cttgtactat ggagaacatg atttggctgg tgctatttcg gaagccctga ttgcaacacc
    28081 agacatgaat gagcatacct tatcagagaa attgtatgag atttcagctg agaactttgg
    28141 gaaacgagtg catgagtttt atctggatgc cattatttca aataacttcc agaaagattt
    28201 ggctaaagat gatacggtca gtcagcgtat ctttaagaca gttttgtatc ttccgcaaca
    28261 ggtggttgct gtacctgtaa aaggatctag acgcatgttg aaggcttcaa aaacacagtt
    28321 gatcagtatg agagactatt ggaaagacca tgaagaatag aaagaggaac agctatgaaa
    28381 aaaacaatta atgagaagcg gtcgtgataa aaagattgcg ggtgtttgtg ctggggtggc
    28441 ccattatctg gatatggatc cgactatcgt tcaagtcatt tggggtgttc ttacttgctg
    28501 ttacggagct ggaattgtag cttacattat tttatggatt atcgcaccag tagcaactga
    28561 ctattgaaaa ctagctcaat tcatgctaag ataatagaaa atagaatgta acgaaggaga
    28621 gaaaaatggc atttggagat aatggaaatc gtaaaaaaac tatgtttgag aaaataacct
    28681 tgtttatcgt gattatcatg ctagtagcaa gtttattggg aatttttgca actgcaattg
    28741 gtgccctcag taatctataa aatagattca agaaaattta gtgactggga tttcccagcc
    28801 cttttttaaa gtgagaagaa ataatgagta tgtttttaga tacagctaag attaaggtca
    28861 aggctggtaa tggtggcgat ggtatggttg cctttcgtcg tgaaaaatat gtccctaatg
    28921 gaggcccttg gggtggtgat ggtggtcgtg gaggcaatgt ggtcttcgtt gtagacgaag
    28981 gactacgtac cttgatggat tttcgctaca atcgtcattt caaggctgat tctggtgaaa
    29041 aagggatgac caaagggatg catggtcgtg gtgctgagga ccttagagtt cgagtaccac
    29101 aaggtacgac tgttcgtgat gcggagactg gcaaggtttt aacagatttg attgaacatg
    29161 ggcaagaatt tatcgttgcc cacggtggtc gtggtggacg tggaaatatt cgtttcgcga
    29221 caccaaaaaa tcctgcaccg gaaatctctg aaaatggaga accaggtcag gaacgtgagt
    29281 tacaattgga actaaaaatc ttggcagatg tcggtttagt aggattccca tctgtaggga
    29341 agtcaacact tttaagtgtt attacctcag ctaagcctaa aattggtgcc taccacttta
    29401 ccactattgt accaaattta ggtatggttc gcacccaatc aggtgaatcc tttgcagtag
    29461 ccgacttgcc aggtttgatt gaaggggcta gtcaaggtgt tggtttggga actcagttcc
    29521 tccgtcacat cgagcgtaca cgtgttatcc ttcacatcat tgatatgtca gctagcgaag
    29581 gccgtgatcc atatgaggat tacttagcta tcaataaaga gctggagtct tacaatcttc
    29641 gcctcatgga gcgtccacag attattgtag ctaataagat ggacatgcct gagagtcagg
    29701 aaaatcttga agaatttaag aaaaaattgg ctgaaaatta tgatgaattt gaagagttac
    29761 cagctatctt cccaatttct ggattgacca agcaaggtct ggcaacactt ttagatgcta
    29821 cagctgaatt gttagacaag acaccagaat ttttgctcta cgacgagtcc gatatggaag
    29881 aagaaactta ctatggattt gacgaagaag aaaaagcctt tgaaattagt cgtgatgacg
    29941 atgcgacatg ggtactttct ggtgaaaaac tcatgaaact ctttaatatg accaactttg
    30001 atcgtgatga atctgtcatg aaatttgccc gtcagcttcg tggtatgggg gttgatgaag
    30061 cccttcgtgc gcgtggagct aaagatgggg atttggtccg cattggtaaa tttgagtttg
    30121 aatttgtaga ctaggagact ggtatgggag ataaaccgat atctttccga gatgcggatg
    30181 gtaattttgt ttccgccgca gacgtttgga atgaaaagaa attggaagaa ctatttaatc
    30241 gtctcaatcc aaatcgtgcc ttgagattgg cacgaactaa aaaggaaaat ccatctcagt
    30301 aaagaagcta aaaaatcccg tgcctcatca gacacgggat tttgtggtac gacaggcatg
    30361 tatagcaaac tgaatctgga atagcacagc atatcttcta aaatattgtt ataaattgat
    30421 ttgaatttca aaattaaatt gtttgattct tatttcaatt tgttatagta tatctgatgt
    30481 caaagttctc ggcgagtcaa atagcgattc ccaagcctga ctatcgtgag gtagcggatt
    30541 aaaatggtct ggggatagac cgttttaagt ctgacgctgg aaataagaat tgtcagaaga
    30601 agggatagcg aaatcgtggc tctacgaaca ggaacgtgat aataaggcgt atatagcgga
    30661 taagagggcc tcaaactcta aagtccaaaa aggtagtcgt aacctatatg cgtaaatcac
    30721 gagagtaatt gaattcgtac taagattttc tattttcact gtaacctttt aacgtcctta
    30781 tatcttgtat acacgaggaa agatgtacga cttatcccgt gaggtctatc actataaaga
    30841 gaaaacgaca gatagaagtg atcctgagtc acggttatct ttaaaataga ttgtctgata
    30901 ggacggtatg tataaaacgc ttctgtgaac tgagagaagg gggagaagtt cttgctaaaa
    30961 tttagttgaa cagccgtatt ccgatactta gataagagat ctagtcttag ctcctactcg
    31021 gtttcagggg ataaaaaagg ggcaatagcg attcgagaaa gattatactc ttcgaaaatc
    31081 tcttcaaatc acgtcaatat cgccttgccg tacgtgtagg at
//
LOCUS       DAVBNZ010000021        30962 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000021 DAVBNZ010000000
VERSION     DAVBNZ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.021"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            289..2790
                     /locus_tag="VQ860_001013"
     CDS             289..2790
                     /locus_tag="VQ860_001013"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET3119451.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIIAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKVEIDGKEIVKVISVPNKLVNIVVK"
     gene            2984..3679
                     /locus_tag="VQ860_001014"
     CDS             2984..3679
                     /locus_tag="VQ860_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3119452.1"
                     /translation="MPVNEYGRMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            3691..4107
                     /locus_tag="VQ860_001015"
     CDS             3691..4107
                     /locus_tag="VQ860_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3119453.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(4922..5014)
                     /locus_tag="VQ860_001016"
     CDS             complement(4922..5014)
                     /locus_tag="VQ860_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET3119454.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ860_001017"
     CDS             5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ860_001017"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET3119455.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            6127..6699
                     /locus_tag="VQ860_001018"
     CDS             6127..6699
                     /locus_tag="VQ860_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET3119456.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            6930..7688
                     /locus_tag="VQ860_001019"
     CDS             6930..7688
                     /locus_tag="VQ860_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET3119457.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            7697..8500
                     /locus_tag="VQ860_001020"
     CDS             7697..8500
                     /locus_tag="VQ860_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET3119458.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            8522..9781
                     /gene="rseP"
                     /locus_tag="VQ860_001021"
     CDS             8522..9781
                     /gene="rseP"
                     /locus_tag="VQ860_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET3119459.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            9794..11647
                     /locus_tag="VQ860_001022"
     CDS             9794..11647
                     /locus_tag="VQ860_001022"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET3119460.1"
                     /translation="MKQSKIPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            11746..13125
                     /gene="bglA"
                     /locus_tag="VQ860_001023"
     CDS             11746..13125
                     /gene="bglA"
                     /locus_tag="VQ860_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET3119461.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            13318..15126
                     /gene="glmS"
                     /locus_tag="VQ860_001024"
     CDS             13318..15126
                     /gene="glmS"
                     /locus_tag="VQ860_001024"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET3119462.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(15264..15341)
                     /locus_tag="VQ860_001025"
                     /pseudo
     CDS             complement(15264..15341)
                     /locus_tag="VQ860_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            15398..16447
                     /locus_tag="VQ860_001026"
     CDS             15398..16447
                     /locus_tag="VQ860_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET3119463.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ860_001027"
     CDS             complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ860_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET3119464.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVQNESV
                     ENSSKKNIPVTPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ860_001028"
     CDS             20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ860_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET3119465.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ860_001029"
     CDS             21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ860_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET3119466.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            22062..24143
                     /gene="fusA"
                     /locus_tag="VQ860_001030"
     CDS             22062..24143
                     /gene="fusA"
                     /locus_tag="VQ860_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET3119467.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLVEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            24247..28638
                     /locus_tag="VQ860_001031"
     CDS             24247..28638
                     /locus_tag="VQ860_001031"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET3119468.1"
                     /translation="MSNSFEILMNQLGIPVEMRQHPALTQADIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKVLSQDFSNQLLQAYYREAFSEGP
                     CASQSFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEDAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQTKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDVQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVERDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGYPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDAVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKNLIEIGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPNKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            28740..29003
                     /locus_tag="VQ860_001032"
     CDS             28740..29003
                     /locus_tag="VQ860_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET3119469.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            28996..29274
                     /locus_tag="VQ860_001033"
     CDS             28996..29274
                     /locus_tag="VQ860_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET3119470.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            29295..29447
                     /locus_tag="VQ860_001034"
     CDS             29295..29447
                     /locus_tag="VQ860_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119471.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            29469..30710
                     /locus_tag="VQ860_001035"
     CDS             29469..30710
                     /locus_tag="VQ860_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET3119472.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            30720..30950
                     /locus_tag="VQ860_001036"
     CDS             30720..30950
                     /locus_tag="VQ860_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3119473.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
BASE COUNT         8792 a         5924 c         7248 g         8998 t
ORIGIN      
        1 gttcttcata aatcaaaaag cgacataggt agtcggctat ttattgtgaa tacattaatt
       61 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcttc
      121 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
      181 catagtcatc aaaattaatg agatacagta tacagttttt cctttaaaca catttcaaat
      241 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttac
      301 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
      361 acaggaacag atgcatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
      421 ggagctggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
      481 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
      541 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
      601 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
      661 gtcaacacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
      721 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
      781 gccattgcca atgaagaagt gcttcctgac ggaacttctg aacgtggagg ctatccagtt
      841 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
      901 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
      961 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
     1021 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtttt ggctcctgaa
     1081 catgaattag tagatgccat cacaagcaca gagcaagcag aagcagtagc agactacaaa
     1141 caccaagcca gccttaagtc agacttggct cgtaccgacc ttgccaaaga aaaaactggt
     1201 gtatggactg gtgcttatgc catcaatcct gtcaatggta aggaaattcc aatctggatt
     1261 gcggattacg ttcttgctag ctatggtaca ggtgcggtaa tggctgtgcc tgcccacgat
     1321 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
     1381 ggaaatgttg aagaagctgc ctacacagaa gatggccttc acgttaattc agacttccta
     1441 gatggactca acaaagaaga cgctattgcc aagattgtgg cttgcttgga agaaaaaggc
     1501 tgtggacaag agaaggtaac ctaccgtctc cgcgactggc tctttagccg tcaacgttac
     1561 tggggtgagc caatcccaat cattcattgg gaagatggaa cttcaacagc tgtccctgaa
     1621 agtgaattgc cacttgtctt gcctgtaacc aaggatatcc gtccctcagg tactggtgaa
     1681 agtccactag ctaacttgac agactggctt gaagtgactc gtgaagatgg tgtcaaaggt
     1741 cgtcgtgaaa caaatactat gccacaatgg gcaggttcaa gctggtacta cctccgctat
     1801 attgacccac acaatactga gaaattggct gacgaggatc tgctcaaaca atggttgcca
     1861 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta cgctcgtttc
     1921 tggcataaat tcctctatga cctcggtgtt gttccaacta aggaaccatt ccaaaaactc
     1981 tttaaccaag ggatgatttt gggaacaagc tatcgtgacc accgtggggc tcttgtggcg
     2041 actgacaagg ttgaaaaacg tgatggttct ttcttccatg tggaaacagg ggaagagttg
     2101 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgtcaaccc agacgatgtg
     2161 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgttcatggg cccacttgat
     2221 gcttcaatcg cttggtcaga agaaggtctg gaaggaagtc gtaaattcct tgaccgtgtt
     2281 tatcgtttga ttacaagtaa ggaaattatt gcggaaaaca atggtgctct tgacaaggtt
     2341 tataacgaaa ccgttaaagc tgtcacagag caaatcgaat cattgaaatt caacacagct
     2401 attgcccaac ttatggtctt tgtcaacgcc gctaacaagg aagacaagct ctatgtggac
     2461 tatgccaaag gatttatcca attgattgcg ccatttgcac ctcacttggc agaagaactt
     2521 tggcaaactg ttgcagcaac aggtgaatca atctcttacg tagcttggcc aacatgggat
     2581 gaaagtaaat tggttgaaga cgaaatcgaa atcgtcgtcc aaatcaaagg taaagtccgt
     2641 gccaaactca tggttgctaa agacctgtca cgtgaagaat tgcaagaaat tgctcttgct
     2701 gatgaaaaag tcaaggtaga aattgacggt aaggaaatcg tgaaagtgat tagtgtacca
     2761 aataaattgg ttaatattgt tgtaaaataa ccaatttatt tgctgatttc caacctcaaa
     2821 cagtttccca aactgtttga gccaactaaa ctcgttaata tcgttgtgaa ataaggtagg
     2881 aatccttcag agtagaatct ggaggatttt ttgaatcttc ttatgaaagt atggtatact
     2941 atgggcaact ataaagtttg aaaagtgaaa aaaggagaaa gctatgccag taaatgaata
     3001 tggtcgaatg attggggagt caatggaagg ttatacacca ggtgaactgc cttctattga
     3061 tttcttagaa gggcgttatg ctaggataga ggctctttca gtggaaaagc atgcggagga
     3121 tttgctagct gtttatgggc ctgatacgcc tcaggagatg tggacctacc tttttcagga
     3181 gccagtagca gatatggggg agctggttag ccttttacat cagatgttgg ctcgtaagga
     3241 ccgtttttac tatgcaatca tagacaaggc gactggtaag gctttgggat ctttttctct
     3301 catgcgcatt gaccagaata accgagtaat agaagtcgga gcagtcactt tttctccaga
     3361 gctaaggggt acacggatag gaactgaagc tcagtatctc ctagctcgct atgtttttga
     3421 ggagctaaac tatcgtcgct acgagtggaa atgcgatgcc ttaaatctgc catccagacg
     3481 agctgcggag cgtttgagct ttatttatga aggaaccttc cgtcaggcag tggtttataa
     3541 gggacgtacg agagatacgg attggttgtc tatgattgat aaggactggc ctcaagtcaa
     3601 agatcgtttg gaaacatggt tgcgtcctga aaattttgat aaaaatggac agcagtacaa
     3661 gagcttgaga gaactttaag aggtgttgag atgattacta ttaaaaagca agaaattgtc
     3721 aagctagagg atgttttaca tctctatcag gctgtcggtt ggacaaatta tacccatcaa
     3781 ccagagatgc tggagcaggc cttatctcat tcattagtaa tttatctggc acttgatggt
     3841 gatgctgtgg tgggcttgat tcgtttggtt ggagatggat tctcatcagt attggttcag
     3901 gatttaatcg ttttaccaat ctatcagcgt caaggaattg gtagtgcctt gatgaaagag
     3961 gctttagagg attacaaaga tgcctatcaa gtccagctgg tgacagaaga gacagaaaga
     4021 accttgggct tctatcgttc tatgggcttt gaaatcttat ccacctataa ttgtataggg
     4081 atgacttgga tgaatcgtaa aaaataacaa aacttgtttt ttcttaagca aaatttaagg
     4141 atggtctagt attatatagt cattaaataa agacctccta actttattta ataaaatcct
     4201 aaactttttt catcacaatc tcctaatgaa gccacccaat caggtggctt ttttgcgtgg
     4261 tgaggtgctg gtgatagaaa ttttttgcaa aatagtaaaa ttttagaaaa gttaagctag
     4321 ttttaagttt cgtcttgtat catgtagtta ttaaataaag acctcctaac tttatttaat
     4381 aaaatcctaa acttttcttt ttcataataa tctcccttaa ctccacccaa tcaggtggag
     4441 ttttttagct ctatttcagg cttttgggga ctattctaaa aataattttt cgatattttt
     4501 cggtattttt cggattttgg tcggggaatt ggcggggact tttttagcga atataactaa
     4561 gaaataggtc tgtggtcgct tcagctagtt caaactcaat ttgattgtaa gtgactgtta
     4621 attgaagaac tggaactact gtaataatga ttttgcttgt ctagtagtgg cgtattaaat
     4681 gaaaagtgac atgtaagatt gtctcttcgt ttacgaaatc aaaatttcta tgaaattgat
     4741 agaatcccta acgttctctt aatcttaacc gtcttgtcgt acagcggttg aagaaaatgt
     4801 aaacctttga caaaattcgt gaactatggg ataataaaaa ggaattgagt actagttcta
     4861 tatcataggc tagaaaagac cccaagctca cgaccaaata agcttgaggt cttttttgac
     4921 actatttgtc cttgtttagc catttatcga ctatacgaag aacgacaccg accacaattg
     4981 gtccgatgat agttttgagt actaattcca tcatgggcta tctcacctcc tttcgtaggc
     5041 ggtgtagaag tgtcgtagaa tattatacca cataagtgct aaacttagga gtcacccaat
     5101 caggtggctt ttttgtttgt ggcttggttt tttgatataa tagagccatg agtagaattt
     5161 tagataatga gataatgggg gatgaggagt tagtagaacg cacgctccgt cctcagtatt
     5221 tacgtgaata tatcggacag gataaggtca aggaccagct acaaatcttt attgaagctg
     5281 ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt tgggcctcca ggtctcggga
     5341 aaacgaccat ggcctttgtt attgccaacg aactgggagt caatcttaag cagacgtcgg
     5401 gtccagtcat tgaaaaagcc ggagatctgg tagctatttt gaatgagtta gagcctgggg
     5461 atgtactttt tattgatgag atccatcgtt tgccaatgtc agtggaagag gtgctttata
     5521 gtgctatgga ggacttctac atagatatta tgattggggc tggtgagggt agtcgtagtg
     5581 ttcatttgga gttaccacct tttaccttga ttggtgcgac gactcgggct ggtatgctct
     5641 ccaatccgct acgggcacgt tttgggatta caggccatat ggagtattat gcccatgctg
     5701 acttgacaga aattgtcgag cggacggcag atatttttga gatggaaatc actcatgagg
     5761 cagcatctga gttggcccta cgtagtcgtg ggacccctcg tattgccaat cgtctcctca
     5821 agcgcgtgcg cgattttgcc cagataatgg ggaatggggt aattgatgat attattaccg
     5881 ataaggcttt gactatgctg gatgttgacc atgaaggttt ggactatgtg gatcaaaaaa
     5941 tccttcgtac catgattgag atgtacagtg gaggacctgt tggtctagga actctttctg
     6001 tgaatatcgc cgaagagcgt gagacagttg aagatatgta tgagccttac ttgattcaaa
     6061 aaggttttat catgcggaca cggtctggac gggtggcgac tgctaaggca tatgagcact
     6121 taggttatga atacagtgaa aaataagcaa gaaatcttag aggcttttag agaaaatcca
     6181 gatatgatgg ccattctgac gatcatccga gaccttggtc tgaaagactc gtggttggca
     6241 gcaggttctg tcagaaattt catttggaat cttttgtcag acaaatcccc ttttgatcat
     6301 gaaacagata tagatgtgat tttctttgat ccagattttt cttatgagga aaccttatta
     6361 ctggagaaaa agctgcgaga ggattttcct cagtaccagt gggaattgaa aaatcaggtc
     6421 tatatgcatc agcacagtcc tcacactgct tcctatacca gttctcgtga tgctatgagt
     6481 aagtatccag aacggtgtac gacagttgga ctgcgcttga atgaagaatc agattttgaa
     6541 ctctatgcac cttatggttt ggaggatatt ttgaattttc aagttcgtcc aactcctcat
     6601 ttcttagaaa atgaagaccg aatggaactc tatcaaacac gtttatccaa gaaaaattgg
     6661 caggagaaat ggaaaaattt gatttttaaa aatacttaag gaaactttaa gctagggagt
     6721 gtacactaag ttcataagtt aagaagacct taacttaaac tcctaaaact ttttcataat
     6781 aatctcccta taaaaataaa gtcgcccaat caggcggctt atttttttga aaaatgggct
     6841 tggtgcctga gaataaatag cttagtgata gaagaaaatg gggaaatatg gtataataaa
     6901 acgatagatt tttgaatagg aataagatca tgtttggatt ttttaagaaa gataaggctg
     6961 tggaagtaga ggttccgaca caggttcctg ctcatatcgg catcatcatg gatggcaatg
     7021 gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg acataaggcg ggcatggaag
     7081 cattgcaaac cgtgaccaag gcagccaaca aactgggcgt caaggttatt acggtctatg
     7141 ctttttctac ggaaaactgg acccgtccag atcaggaagt caagtttatc atgaacttgc
     7201 cagtagagtt ttatgataat tatgtcccgg aactacatgc gaataatgtt aagattcaaa
     7261 tgattgggga gacagaccgc ctgcctaagc aaacctttga agctttaacc aaggctgagg
     7321 aattgactaa gaacaacaca ggattgattc ttaattttgc tcttaactat ggtggacgtg
     7381 ctgagattac acaggcgctt aagttgattt cccaggatgt tttagatgcc aaaatcaacc
     7441 caggtgacat cacagaggaa ttgattggta actatctctt tactcagcat ttgcctaagg
     7501 acttacgaga cccagacttg attatccgta ctagtggaga attacgtttg agcaatttcc
     7561 ttccatggca gggagcctat agtgagcttt attttacgga caccttatgg cctgattttg
     7621 acgaagcggc cttgcaggaa gctattcttg cctataatcg tcgtcatcgc cgatttggag
     7681 gagtttagga ggaaatatga cccaggattt acagaaaaga accttgtttg cagggattgc
     7741 cctggctatt ttcctaccaa ttttaatgat tgggggcctc ttgcttcaga tagcaatcgg
     7801 aatcatagcc atgctagcca tgcatgaact tttgaagatg agaggtctag agaccatgac
     7861 gatggagggc ctcttgaccc tctttgcaac ctttgcattg accattccct tggagaatta
     7921 cctgactttt ttgccagttg atgggaatgt ggttgcctat agtgttttga tttcaatcat
     7981 gttaggaacg accgttttta gcaagtctta tacgattgag gatgcggttt tccctcttgc
     8041 tatgagcttc tacgtgggct ttggatttaa tgctttacta gatgctcgtg ttgcaggttt
     8101 ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca gacagtggtg cctatcttgt
     8161 tgggatgaac tatgggaaac gaaagttagc accaagggta tcgcctaata aaacccttga
     8221 gggtgccttg ggtggtattt taggagcaat tttagtaacc attatcttta tgatagttga
     8281 cagtacagtt gctcttccat atggaattta caagatgtca gtctttgcta ttttctttag
     8341 cattgctgga caatttggtg atttactaga aagttcgatc aaacgtcatt ttggtgttaa
     8401 ggattctggg aaatttatcc ctggacatgg tggtgttttg gatcgtttcg atagtatgtt
     8461 gcttgtattt ccaatcatgc acttatttgg actcttttaa tcaaaagacg gaggaaacgc
     8521 tatgctcgga attttaacct ttattctggt tttcgggatt attgtagtgg tgcacgagtt
     8581 cgggcacttc tactttgcca agaaatcagg gattttagta cgtgaatttg ccatcggtat
     8641 gggacctaaa atttttgctc acattggtaa ggatggaacg gcctatacca ttcgaatctt
     8701 gcctctgggt ggctatgtcc gcatggccgg ttggggtgat gatacaactg aaatcaagac
     8761 aggaacgcct gttagtttga cacttgctga tgatggtaag gttaaacgca tcaatctctc
     8821 aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg acccagtttg attttgaaga
     8881 caagctcttt atcaaaggat tggttctgga agaagaaaaa acatttgcag tggatcacga
     8941 tgcaacggtt gtggaagcag atggtactga ggttcggatt gcacctttag atgttcaata
     9001 tcaaaatgcg actatctggg gcaaactgat taccaatttt gcaggtccta tgaacaattt
     9061 tatcttaggt gtcgttgttt tttgggtttt aatctttatg cagggtggtg tcagagatgt
     9121 tgataccaat cagttccata tcatgcccca aggtgccttg gccaaggtag gagtaccaga
     9181 aacggcacaa attaccaaga ttggctcaca tgaggttagc aactgggaaa gcttgatcca
     9241 agctgtggaa acagaaacca aagataagac ggcaccgact ttggatgtga ctatttctga
     9301 aaaggggagt gacaaacaag tcactgttac acccgaagat agtcaaggtc gttaccttct
     9361 aggtgttcaa ccgggggtta agtcagattt tctatccatg tttgtaggtg gttttacaac
     9421 tgctgctgac tcagctctcc gaattctctc agctctgaaa aatctgattt tccaaccgga
     9481 tttgaacaag ttgggtggac ctgttgctat ctttaaggca agtagtgatg ctgctaaaaa
     9541 tggaattgaa aatatcttgt acttcttggc aatgatttcc atcaatattg ggatttttaa
     9601 tcttattccg attccagcct tggatggtgg taagattgtg ctcaatatcc tagaagccat
     9661 ccgccgcaaa ccattgaaac aagaaattga aacctatgtc accttggccg gagtggtcat
     9721 catggttgtc ttgatgattg ctgtgacttg gaatgacatt atgcgactct tttttagata
     9781 atcgaggaat attatgaaac aaagtaaaat acctatccca acgcttcgcg aaatgccaag
     9841 cgatgctcaa gttatcagcc atgctcttat gttgcgtgct ggttatgttc gccaagtttc
     9901 agcaggtgtt tattcttatc taccacttgc caaccgtgtg attgaaaaag ctaaaaacat
     9961 catgcgccaa gaattcgaaa agattggtgc tgttgagatg ttggctcctg cccttcttag
    10021 tgcagaattg tggcgtgaat caggtcgtta cgaaacctat ggtgaagacc tttacaaact
    10081 aaaaaaccgt gaaaaatcag actttatctt aggtccaact cacgaagaaa cctttacagc
    10141 tattgtccgt gattctgtta aatcttacaa gcaattgcca ctcaaccttt atcaaattca
    10201 gcccaagtat cgtgatgaaa aacgcccacg taatggactt cttcgtacac gtgagtttat
    10261 catgaaggat gcttatagtt tccacgctaa ctatgatagt ttggatagtg tttatgatga
    10321 gtacaaagca gcctatgagc gtattttcac tcgtagtggt ttagacttca aggctattat
    10381 tggtgacggt ggagccatgg gtggtaagga tagccaagaa tttatggcca ttacatctgc
    10441 tcgtacagac cttgaccgct gggttgtctt ggacaagtca gttgcctcat ttgacgaaat
    10501 tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc aaatggatag tctctggtga
    10561 agataccatt gcttactcaa gtgagtctag ctatgcagct aacttagaaa tggcaacaaa
    10621 cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa gttactcgtg ttgcaacgcc
    10681 agatgttaaa tcaattgatg aagttgcagc tttcctcaat gttccagaag aacaaacgat
    10741 taaaaccctc ttctacattg cagatggtga gcttgttgca gcccttctag ttggaaatga
    10801 ccaactcaac gaagtcaagt tgaaaaacca cttaggagca gatttctttg acgttgctag
    10861 cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt tcacttggac cagttggttt
    10921 gccagagaat attaaaatta ttgcagatcg taaggtgcaa gatgttcgca atgcagttgt
    10981 cggtgctaac gaagatggct accacttgac tggtgtgaac ccaggccgtg attttacttc
    11041 agaatatgtg gatatccgtg aagttcgtga gggtgaaatt tccccagatg gacaaggtgt
    11101 ccttaatttt gcgcgtggta ttgagatcgg tcatattttc aaactcggaa ctcgctattc
    11161 agcaagcatg ggagcagatg tcttggatga aaatggtcgt gctgtgccaa tcatcatggg
    11221 atgttacggt atcggtgtca gccgtcttct ttcagcagtg atggagcaac acgctcgcct
    11281 ctttgttaac aaaacgccaa aaggtgaata ccgttacgct tggggaatca atttccctaa
    11341 agaattggca ccatttgatg tgcatttgat tactgtcaat gtcaaggatg aagaagcgca
    11401 agccttgaca gaaaaacttg aagcaagctt gatgggagct ggttatgaag tcttgacaga
    11461 tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt gacttgattg gtcttccaat
    11521 ccgtatcact gttggtaaaa aagcggccga tggcattgta gaagttaaga tcaaggcaac
    11581 tggtgacacc attgaggttc atgcagataa cgtgcttgaa acgcttgaaa tcctaagcaa
    11641 gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat gtaactagtt tttaccttgt
    11701 tttttctgta taatgggaga aatgagtaga taaagaggta aatgtatgct aagatttcca
    11761 aaggattttg tctggggatc ctctacttct ggaccgcaga cagaaggacg tgtagctggt
    11821 gacggtaagg gagacaatct ctgggattac tggttccaag tggagccaaa tcgttactat
    11881 aatgggattg gttcagataa gacatcgact ttttatgaaa attgggagcg ggatattgag
    11941 cttttgttag agactggtca cacagccttt cggacttcta ttcagtggtc acggattttt
    12001 ccacaaggct gtggaaaagt caaccctcaa ggtgtggatt tttatcgtaa ggtctttgag
    12061 gctattaagg ctaaaggaat tcgtctgtta gtcaatctct atcattttga tttacctttt
    12121 gcccttcaag aggatggtga tggttgggaa aataaggcga cagtctcagc ctatgaagac
    12181 tatgctcgtt tttgttttga gacttatgga gatttagtgg atcaatggat tacctttaac
    12241 gagcccatcg ttcctgtaga atttggttat ttttatgatg cccattatcc acataaggtg
    12301 gatgcagagg cagctgttaa ggtagcctat catacacaat tggccagcag ccgggctgtt
    12361 aaggcttgcc atgaactttt gcctgattcc aagattggga ttgtcctcaa cttgacaccg
    12421 gcttatccac gtagccagca tcctgctgat gtcaaggcag ctcgtattgc ggcccttttt
    12481 caggcccaat ctttcttaga tccatctgtc ttggggactt atccacagga gttggtagaa
    12541 atcttgcatg aacacggtct tttacctgat gctacagagg aagagttgga actcattcgt
    12601 gataatacgg tggacttcct tggtgtgaac tactatcaac ctttgcgtgt tatggctcct
    12661 cgatttgcta agcatccaga gagtccactc ttaccagaac atttttacga gccttatgtg
    12721 atgcctggac gtaaaatcaa ttctcaccgt ggttgggaga tttatgagca agggatttat
    12781 gacatcgccc aaaatatcaa ggaaaattat ggcaatattg agtggatgtt gactgagaat
    12841 ggtatgggtg ttgaagggga agaaaaattc cgtcaagatg gaatgattca agatgattac
    12901 cgtattgact ttgtaaaagg tcatcttcgt gaacttcacc gtgccattga agatggtgcc
    12961 aactgtaagg gctacttgat ttggaccttt attgactgct ggtcatggct caacagctat
    13021 aaaaatcgct atggtttggt cgaattagac ttggaaacgc aagaacgtcg tctgaagaaa
    13081 tcaggccact ggttcaaaga attaagcgat aataatggat tttaaaaagg actctgactg
    13141 attatcccaa tcggtcagag tttttatgct tacaggagct taatttgaac tataccaatt
    13201 tttactcttg acaagtgaaa gaaacaagta tatactgttt ttgctgattc tataaaagat
    13261 gaattagact ataccaattt taaggagaaa gcacagcttg cctgtgtcgt atatactatg
    13321 tgtggaattg ttggtgttgt tggaaacaca aatgcaactg atattttgat tcaagggctt
    13381 gaaaagcttg aataccgtgg ctatgattct gcgggaattt ttgtcctaga tggtgctgat
    13441 aaccatttag tgaaggcggt tggtcgtatt gcagaattgt ctgccaagac agctggtgtt
    13501 gagggaacaa ctggtatcgg acatactcgt tgggctactc acggaaaacc aactgaggac
    13561 aatgctcacc cacaccgctc tgagacagaa cgctttgtct tggtgcataa tggggtgatt
    13621 gagaactatc ttgaaatcaa ggaagaatac cttgcaggtc accacttcaa ggggcagaca
    13681 gatactgaaa tagccgttca tttgattgga aaatttgcgg aagaagaagg gctctcagtt
    13741 cttgaagcct tcaaaaaagc ccttcacatc atccgtggtt cttatgcctt tgccttggtt
    13801 gactcacaag atcctgaagt catctacgta gctaaaaata aatcaccact tttgattggt
    13861 cttggagaag gctataacat ggtctgctca gacgccatgg ctatgattcg tgaaactaac
    13921 caatacatgg aaatccatga ccaagagttg gtaatcgtca aggctgatag tgtggaagtt
    13981 caagactatg atggaaatcg tcgtgagcgt gctagctaca ctgctgaact tgacttgtca
    14041 gatatcggta agggaactta cccttactac atgctcaagg aaattgacga gcaaccaact
    14101 gttatgcgga aactcatcca agcctacaca gatgaggctg gtcaagttgt cgtagaccca
    14161 gatatcatta aggctgttca agacgcagac cgcatctaca tccttgcagc tggaacatct
    14221 taccatgcag gatttgcttc taagaaaatg ttggaagaat tgacagatac accagttgaa
    14281 cttggaatct catctgagtg gggctacggt atgccacttc tcagcaagaa accactcttc
    14341 atctttatca gccaatctgg tgaaacagcg gatagtcgtc aagttttggt caaggctaat
    14401 gaaatgggaa ttccaagctt aacagtgaca aacgttccag gttcaaccct ctcacgtgaa
    14461 gccaactata ccatgctcct tcacgcaggt cctgaaattg ccgtggcatc aactaaagcc
    14521 tatacagcgc aaatcgcagc ccttgccttc cttgcaaaag cagtcggaga agcaaatggt
    14581 aatgctaaag cgcaagcctt tgacctggtt catgaattgt caatcgtagc tcagtctatc
    14641 gaatcaactc tttcagagaa agaaaccatt gaagccaagg ttcgtgaact tcttgaaaca
    14701 actcgtaacg ccttttacat cggacgtggt caagattact acgtagccat ggaagcaagt
    14761 ctcaaactca aagagatttc ttatatccag tgtgaaggct ttgctgcagg agaactcaag
    14821 cacggaacca ttgccttgat tgaagaagga acgcctgttt tggctctctt gtcagatcca
    14881 gttcttgcca atcatactcg tggaaatatc caagaggtcg cagcccgtgg tgccaaagtc
    14941 ctcactatcg cagaagagaa tgtagccaaa gataccgacg atatcgtcct tacgaccgta
    15001 catccatacc tctcaccaat ttcaatggtc gtaccaacgc aattagtcgc ttactttgca
    15061 accctccacc gtggcctcga tgtggacaaa ccacgtaacc ttgccaagtc agtaacggta
    15121 gaataagcta aaaaagtcta gttatctagg cctttttctt gtgagcaaat tggttgcttg
    15181 tactcaagat tcgtgttata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
    15241 ccgtaggtat ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca ctgttttgag
    15301 cagcctgcag ctagcttcct agtttgctct ttgattttca ttgagtatta gaataatttt
    15361 tcaaattgaa gtacagagat agataaggag aatcacaatg gtagaattgg gaatttcaac
    15421 atttggggaa ataacggagc ttgaagggac tggacaaact tacagtcatg ctgaacgcat
    15481 tcgccagttg gtggcagaga ttgagctggc tgacaaggtt ggtttggatg tatatgggat
    15541 tggtgagcac catcgggcgg attttgcagt atcagcccca gagattgttc tggccgctgg
    15601 ggcagtcaat accaagaaaa tccgtttgac cagtgcagtc agcattctgt caagcatgga
    15661 cccgattcgt ttgttccaac agtatgccac tatcgatgct ttgtcaaatg gacgagcgga
    15721 gattatggct ggaaggggct ctttcacgga atctttccct ctgtttggtt atgacttgaa
    15781 agactacgac tctctttttg atgagaaatt agacttgctt cagttagtca atgaaaagac
    15841 caagttagac tggcaaggtc gattgactca aacgattgct ggtaaagaag tttatcctcg
    15901 tccagttcag gacaaattgc ccttgtggat agctacaggt ggtcatgtcg aatcaacagt
    15961 gaagattgct caggctggtc taccgattgt atatgctatt attggtggta atccacgtta
    16021 ttttaaaaag ttgattcagg cttatcgtga gattggaagc gaagcgggtc atgctgacaa
    16081 agacttgaaa gtgggagccc attcttgggg gtggattgcg gaagatggtg agcaggcggt
    16141 gaaagattat ttccatccga ctaagcaagt ggtggatgct atttccaaag accgtccgca
    16201 ctggcaggaa ttgcgttatg agcaatattt ggagcaggta gggccaaatg gcgccatgtt
    16261 tgttggcaat ccagatcagg tggccgaaaa attgattcgc atgatagagg atttaggatt
    16321 ggaccgcttc atgcttcatc taccgcttgg ttctatgcct catgaccagg ttctgagagc
    16381 tattgaactc ttcggaacac aagttgcacc caaagtacga gcttattttg ctatgaaaga
    16441 ggcttaataa aaaatcctaa tcaagtttat taggacaaca aatattgtac gaaaattaat
    16501 cccccgagct ataatgcttg ggggattttt ctataggagg gctagtttag ttctcttttt
    16561 tattttttag taagaaaccg agaccaagga gcgcaaggag gctgattcct gcaaatagga
    16621 gtttgttttc gtttttgatt cctgtatttg gaagttcagc ttgtttatct ggggttacag
    16681 gtatattttt cttgctagag ttttctaccg attcgttttg aaccgcttct tttacagatg
    16741 atgcttgtgc ttcttgtgct ggttgttcag cttgtgaatc agctgtagct tggctaggtt
    16801 tattttccgc atcagctact ttggcatctg gtttagtaga atcaggtcta gcttctggag
    16861 ctgggtcttg atgttcaggc ttggaagggg ttgagtctgg tttctcttct gcagttgact
    16921 catggctagt tccattttga gagactcgaa gaacagtagc tgtaagggca ttcaatttca
    16981 agcctttttc agtccattca agtcctttcg ggttggcaat tccgactgat cctgcttggt
    17041 tttcatctgc caaaacttcc gcatttctta gatgtgcaaa ggcagttccc aaattaaatt
    17101 cgcgagcttt ttcatccgca ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga
    17161 tttggtagcc aatcactaca tcctcttttt ccacaccatt ttggcctggg acagtgatga
    17221 ggtggacacg gtctttgata tcttggagac tcttaagtcg gaaggcatct gtagattgac
    17281 gaagggcaat caaacctttc atatagtcac ggctcttgac attttcagga taagctttac
    17341 catctgtagc cttagtccag tcaaacttgt tgactgcgtc gctagaatcg taagaatcat
    17401 ggatgaagta aggatagtca aatgggttgc cgtccttatc acgcaacaag tgagatttgt
    17461 ttggaacctt atcctctgct actggagtct tgtaggctgg gtcacggaat tgtttagtac
    17521 gtccatattc ctgaccggag tggataaatg gagttccttg agctgtcaag accatgagat
    17581 ttccaagtcg taaacgacgg tggatttcag catagttctc agccttgctt gggtcttttt
    17641 tgatagactg ggcaatgatg tcaaagaggg tcaagttatc atgggctgcg atgtattgga
    17701 tgacatctcc agggctgtca gcttcaaagt tagttggctg agcaatgaga tttttaaaga
    17761 tagtgttaac atcacgcttg ccacctgtga taaaggcagg ttgaccttcg tttggataac
    17821 cagatttgag gttgttacgg atgtcatctg aaaagacagc gacagtatcg gtatgtttca
    17881 tccaatcttg gtcagcagct ttagtaggca tgttttcatc accggcatag gttctccaac
    17941 cttcgcctaa catgattaga tttggattga gggcgcgtgc agccttgtaa gcttcttcga
    18001 tagaagcggc gtcatggtct cccatcatat cgaaacggaa tccatccact ttgtaggtat
    18061 caactaggta tttgatagag tcaactagga ggcgtttggt catatggtgg gttgtcccca
    18121 agcgtccacc accaaagcta gttcgaggtg tgccatcggc atccataaag tggtagtagt
    18181 ttggctctag gtcttcaaag atatcgactt tggctgtgtg gttataaacg acatctagga
    18241 tagctcccat accacgtttg tggatttcgt tgatgaggtt tttaaattct gcgattcgtt
    18301 tttctggatt cttaggatcg cttgagtaca taccagtcaa ggagaagtag ttttgagggt
    18361 catatcccca gttgtagttg ctgttgcttg aagcatagtc agacaagcgt tcatggtttt
    18421 tcaattcatt gacaaagtag taagacaaga ctggaaggag ctggatatgg gttacaccca
    18481 agtctttgag atagtctagt ttttcaatga aggcttcaaa agtcccaaat ggtttggtca
    18541 agtcttttgc aatggcagga tctgaagtga agtcacgcac atgagcttcg tagataacgg
    18601 cgtcttcacg agtcttgaaa ttgtgaatct taccataagt caagtcttga ggtccgagtt
    18661 tagctggatc tacaaaggcg gctttagcca ctttatgggc atcgtcaatc ttggcatcgt
    18721 cgctattcca agcagcaaga gatttagcgt aaggatcgag tgcaagaaca gttttacctt
    18781 gacgctcgat ttggtattga taatagtagc cagtgaaatc tgtgattccg agtttgtttg
    18841 tgctgtctag agtttgtttc caagttcctc tttccccttt ttcgagagcg acagttccaa
    18901 ctactttgtc agggtcattc ttgtcgtaga caacaacaga aaccttatca gcacttggtg
    18961 accaaagggt caaatcaact tgttttcctt cttcttttag gtcagctccc agtttgccat
    19021 catagctgta tgtctcatct ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat
    19081 tgtagctaac agtataagga tgttttgtgt cagagaaatc tccgctgtag gtcactttct
    19141 taccagcttc atcgattgca acatcggtaa tagttacctt gtttcctagg tgattagtga
    19201 tgttggagtg tttgaggata tcttcttttt tagcaccgac aagtgttgaa aagctacttt
    19261 caatgctaga agtgcctacg tgttgggctc ctgtcatacg gatatcatgg acatagtatg
    19321 gatttgtgta aatcgattca tcatcgtctt ttaggaaaat ttggctatga tttttcaaat
    19381 ctgtgaactt ataattttct ttacggattt tcacgtcgtc tccttgtttg ctctcatcta
    19441 gtaataaaaa tccaaattct cttgcggctt cattaagagg aatgtcgata tagcggccat
    19501 atttgcctgt agccgtaaag tctgttccgt caggccattg agcgctactt ggatttttta
    19561 catctcccca gtaccagaga gatttcttgt catagttgcc atctgtgcgg tagtagttga
    19621 cgcgaacagt tcctgcaggc tgtggctcgt aagagaaaac cttgtaatct tggtctaacc
    19681 aagcttcgtt catttttgga actagttttt ctacagattt atcgccggtt agattttttc
    19741 cagctgtatt gttgatgagg aagctaattt tcttggcttg ttctcccttt aatttgacat
    19801 ctaggtaata gccgtagtca tctttcttgg catccttgaa ggacaaagct ccgtttggcc
    19861 agttttcaga tggtttttca acatcgtccc aagtccatag tccttgagca tccttgtttt
    19921 cttcaggaag ttttttgaca tggatacgga agtagttatc ttcgatgggc tcttctgcct
    19981 tagtttcagt tgttactgga ctagtagaag tagttggctc tgttgcaggt ttttcttctg
    20041 ttttctctag ggaagcgttt gcatttctag gtgaagaaat atcactttcg ttcttaccag
    20101 agccagctgc tgtatcagta agaggttggg caagggtggt tgtatttctg ttgttgggtt
    20161 cgttagtggt tggtgtactt tcgtcggatg agatagttgg tgtagccatg gcaagcaaga
    20221 caaggcttgc gccgataagg acagaaccag ttccattttt gagggaacgg atgctgtaga
    20281 ccattttttt ctcagtgtga gatggtgttt ttctcataat gattctccaa tcaataaatt
    20341 tctatatcag tatagcatgt agtaaaacaa tatgcaagcg ttttctttga tttgtgaaaa
    20401 aaattcctac ttttgagaag ttttctgtac tattttatat atcagtataa atgacggaga
    20461 taaaaatgtc acataagcca agccgtatta ttaggaagat gatgtgttcc cagctatttt
    20521 tattcagaaa ttgatctcta acattaccaa taaaaatgaa aaatatcttg acaagcaagg
    20581 gaaaattttg ttacaataat agacggtact ttttactttt ggtctctcaa gagtgtacag
    20641 ggacgtgctg acaaatgttg caaaagtaca cacagatgat atctgtcacc aagtgtatca
    20701 tcaccaaaaa taaaaaaaca caggagaatg tagatgccta caattaacca attggttcgc
    20761 aaaccgcgta aatcaaaagt agaaaaatct aaatcaccag ctttgaacgt tggttacaat
    20821 agtcataaaa aagttcaaac aaacgtttct tcaccacaaa aacgtggtgt tgcaactcgt
    20881 gttggaacaa tgacacctaa aaaacctaac tcagcccttc gtaaattcgc tcgtgtacgt
    20941 ttgagcaacc ttatcgaagt tactgcctac atcccaggta tcggacacaa cttgcaagag
    21001 cacagcgtgg tgcttcttcg cggtggacgt gtaaaagacc ttccaggggt acgttaccat
    21061 atcgtccgtg gtgcacttga tactgcaggt gttaacgatc gtaaacaagg ccgttctaaa
    21121 tacggtacta aacgtccaaa agcataagga aaggggataa agagaaatga gtcgtaaaaa
    21181 tagagctcca aaacgtgacg tattgccaga tccgctatac aattcacaac tagttactcg
    21241 tcttatcaac cgcgttatgc ttgatggtaa acgtggtact gctgcttcaa tcgtttacgg
    21301 tgcttttgag caaatcaaag aagctactgg caacgatgca cttgaagtat ttgaaacagc
    21361 tatggaaaac atcatgcctg tacttgaagt acgtgcacgt cgtgttggtg gttctaacta
    21421 ccaagtccca gttgaagttc gtccagaacg tcgtacaaca cttggacttc gttggttggt
    21481 aacaatcgct cgtcttcgtg gtgaacacac aatgcaagac cgtcttgcaa aagaaatctt
    21541 ggatgctgct aacaacactg gtgcagcagt taagaaacgt gaagatactc accgtatggc
    21601 tgaagctaac cgtgcattcg cacacttccg ttggtaagat aggatgcgaa agcgttaaga
    21661 aagtcccaga gaaaataggg aatcgaagca ggttgcggtt gcaaccaatg agattcatct
    21721 ttttctccag acttttagct tgagctcaac taaatcatga tgctaggcac ggtaaggatg
    21781 caaggtgaaa ataggaaact gacgcagtat tcaacgaata caaggagttt tatctttttc
    21841 acgcagcatc ccgttccagc tcacatcggc taactaactt tagcctgggt tcaaattagc
    21901 taaatcgatt agtattagct ataactcagc ttaccatctc gtaagttgaa accaacaata
    21961 gcatgaaaac attgagaacg ggtaggtcct gcctatccgt ttttattaaa atcgtgttat
    22021 aatagaatag aaatcaaaaa taaataggag aaacaaacct catggcacgc gaattttcac
    22081 ttgaaaaaac tcgtaatatc ggtatcatgg ctcacgtcga tgccggtaaa acaacaacta
    22141 ctgagcgtat tctttactac actggtaaaa tccacaaaat cggtgaaact cacgaaggtg
    22201 cgtcacaaat ggactggatg gagcaagagc aagaacgtgg tatcacgatc acatctgctg
    22261 cgacaacagc tcaatggaac aaccaccgcg taaacatcat cgacacacca ggacacgtgg
    22321 acttcacaat cgaagtacaa cgttctcttc gtgtattgga tggtgcggtt accgttcttg
    22381 actcacaatc aggtgttgaa cctcaaactg aaacagtttg gcgtcaagca actgagtacg
    22441 gagttccacg tatcgtattt gccaacaaaa tggacaaaat cggtgctgac ttcctttact
    22501 ctgtaagcac acttcacgat cgccttcaag caaatgcaca cccaatccaa ttgccaatcg
    22561 gttctgaaga tgacttccgt ggtatcattg acttgatcaa gatgaaagct gaaatctata
    22621 ctaacgacct tggtacggat atccttgaag aagacatccc agctgaatac cttgaccaag
    22681 ctcaagaata ccgtgaaaaa ttggttgaag cagttgctga aactgacgaa gaattgatga
    22741 tgaaatacct cgaaggtgaa gaaattacta acgaagaatt gaaagctggt atccgtaaag
    22801 cgactattaa cgttgaattc ttcccagtat tgtgtggttc agccttcaag aacaaaggtg
    22861 ttcaattgat gcttgatgcg gttattgact accttccaag cccacttgac atcccagcaa
    22921 tcaaaggtat taacccagat acagatgctg aagaaactcg tccagcatct gacgaagagc
    22981 catttgcagc tcttgccttc aagatcatga ctgacccatt cgtaggtcgt ttgacattct
    23041 tccgtgttta ctcaggtgtt cttcaatcag gttcatacgt attgaacact tctaaaggta
    23101 aacgtgaacg tatcggacgt attcttcaaa tgcacgctaa cagccgtcaa gaaattgaaa
    23161 ctgtttactc aggtgatatc gctgctgccg ttggtttgaa agatactaca actggtgact
    23221 cattgacaga tgaaaaagct aaaatcatcc ttgagtcaat caatgttcca gaaccagtta
    23281 tccaattgat ggttgagcca aaatctaaag ctgaccaaga caagatgggt atcgcccttc
    23341 aaaaattggc tgaagaagat ccaacattcc gcgttgaaac aaacgttgaa actggtgaaa
    23401 cagttatctc tggtatgggt gagcttcacc ttgacgtcct tgttgaccgt atgcgtcgtg
    23461 agttcaaagt tgaagcgaac gtgggtgctc ctcaagtatc ttaccgtgaa acattccgcg
    23521 cttctactca agcacgtgga ttcttcaaac gtcagtctgg tggtaaaggt caattcggtg
    23581 atgtatggat tgaatttact ccaaacgaag aaggtaaagg attcgaattt gaaaacgcaa
    23641 tcgtcggtgg tgtggttcct cgtgaattta tcccagcagt tgaaaaaggt ttggtagaat
    23701 ctatggctaa cggtgttctt gcaggttacc caatggttga cgttaaagct aaactttacg
    23761 atggttcata ccacgatgtc gactcatctg aaactgcctt caagattgcg gcttcacttg
    23821 ctcttaaaga agctgctaaa tcagcacaac cagcgatcct tgagccaatg atgcttgtaa
    23881 caatcactgt tccagaagaa aaccttggtg atgttatggg tcacgtaact gctcgtcgtg
    23941 gacgtgtaga tggtatggaa gcacatggta acagccaaat cgttcgtgct tacgttccac
    24001 tcgctgaaat gttcggttac gcaacagttc ttcgttctgc atctcaagga cgtggtacat
    24061 tcatgatggt atttgaccac tacgaagatg tacctaagtc agtacaagaa gaaatcatta
    24121 agaaaaacaa aggtgaagac taatcagtcc tcactctaga aggaagtcac ttagtggctt
    24181 ccttttgtct ttagaaaata cctctaaata tggtaaaata gtagaagaat aatgtgagga
    24241 aaatgaatgt caaatagttt tgaaattttg atgaatcaat tggggatacc tgttgaaatg
    24301 agacagcatc ctgctttaac acaggcagat attgagcgag tcgtggttca taaaattagt
    24361 aaggtatggg agtttcattt cgtattttct aatattttac cgattgaaat ctttttagaa
    24421 ttaaagaaag ggctgagtga ggaattttct aagacaggca ataaagctgt tttcgaaatc
    24481 aaggttctgt ctcaagattt ttcaaatcaa ctcttgcagg cttattatag agaagctttt
    24541 tctgagggtc catgtgctag tcaaagtttt aagtctcttt atcaaaattt gcaagttcgt
    24601 gctgagggga atcaactctt tattgaagga tctgaggcga ttgataagga acactttaag
    24661 aaaaatcacc ttcctaattt agcaaaacaa cttgaaaagt ttggttttcc aacttttaac
    24721 tgtcaggtcg agaagaatga tgtgctgacc caagagcagg aagatgcctt ccatgctgaa
    24781 aatgagcaga ttgttcaagc ggccaatgag gaagcgctcc gtgctatgga acaactagaa
    24841 cagatggcgc cacctccagc ggaagagaaa ccagcctttg attttcaaac gaaaaaagct
    24901 gcagctaaac ccaagctaga taaggcggag attactccta tgatcgaagt gacgacggag
    24961 gaaaatcgtc tggtctttga aggggttgtg tttgatgtgg agcaaaaagt gaccagaaca
    25021 gggcgtgttt tgatcaactt taaaatgacg gactacactt caagtttttc gatgcaaaag
    25081 tgggtaaaaa atgaggaaga ggctcagaaa tttgatctca tcaagaagaa ttcttggctc
    25141 cgagttcgtg ggaatgtgga gatgaataac ttcacacgcg atttgactat gaatgtgcag
    25201 gatgtgcagg aagttgttca ctatgagcgg aaggatttga tgccagaagg tgagcgtcgg
    25261 gttgagtttc acgctcatac taacatgtcg actatggatg ctctaccaga ggttgaagaa
    25321 atcgttgcta cagctgctaa gtggggacac aaagcagttg ctatcaccga ccacgggaat
    25381 gttcaatcct tcccacacgg ctataaggcg gctaagaaag cgggaatcca gctaatctat
    25441 gggatggaag ccaatatcgt ggaggaccgt gtccctatcg tctataacga agtggagagg
    25501 gacttgtcag aagcgaccta cgtggtcttt gacgtggaaa cgacgggtct atcagccatc
    25561 tataatgatt tgattcaggt tgcggcctct aagatgtaca aggggaatgt cattgctgaa
    25621 tttgatgaat ttatcaatcc tgggtatccc ttgtcagctt ttactactga gttgactgga
    25681 attacagatg atcacgtcaa aaatgccaaa ccactagaac aagttctgca agaattccaa
    25741 gaattctgca aggatacggt cctagttgcc cacaatgcga cctttgacgt tggctttatg
    25801 aatgccaact atgagcgtca tggtcttcct aaaattagcc agccagttat tgatacgctg
    25861 gagtttgcta gaaacctcta tcctgagtat aaacgtcatg gtttggggcc tttgactaag
    25921 cgttttggtg tggctttgga acatcaccac atggccaatt acgatgcgga agctactggt
    25981 cgtctgctct ttatttttat caaagaagta gcagaaaaac atggagtgac cgatctagct
    26041 agactcaaca ttgatttgat tagtccagat tcttataaaa aagctcggat caagcatgcg
    26101 actatttatg tcaagaatca ggtaggtcta aaaaatatct ttaagctagt ttctttgtcc
    26161 aatactaagt actttgaagg ggtgccacga attccgagaa cagttctaga tgcccatcgg
    26221 gaaggtttga ttttaggttc agcttgctct gaaggtgaag tttttgatgc ggttgtttcc
    26281 caaggtgtgg atgcggcggt tgaggtggcc aagtattatg actttatcga ggtcatgcca
    26341 ccagctatct atgctccctt gattgccaag gagcaggtca aggatatgga agaactccag
    26401 actattatca agaatttgat agagatcggc gaccgtcttg gcaagcccgt tttggctacg
    26461 ggaaatgtcc actatatcga accagaagaa gaaatttacc gtgaaattat cgtccgcagt
    26521 ttgggtcagg gggcgatgat taaccgaacc atcggtcatg gtgaacatgc ccaaccagca
    26581 ccacttccaa aggctcattt tagaacgact aatgagatgt tggatgaatt tgccttcttg
    26641 ggagaggaac tagcccggaa attggttatt gaaaacacca atgccttggc agaaatcttt
    26701 gaacccgttg aggtagttaa gggtgacttg tatacgcctt tcattgacaa ggctgaagaa
    26761 acagttgctg agttgaccta taagaaagct tttgagattt atggaaatcc gttgccagat
    26821 attgttgatt tgcgaattga aaaagaattg acttccattc tggggaatgg atttgctgtg
    26881 atttatctgg catcgcagat gctggttcaa cgttccaatg aacggggtta cctggtgggt
    26941 tctcgtgggt ctgtaggatc tagtttcgtt gcgactatga ttggtattac ggaggttaat
    27001 cctctctctc ctcactatgt ctgtggtcag tgtcaataca gcgagtttat caccgatggt
    27061 tcttatggtt caggttttga tatgcccaat aaggactgtc caaactgcgg tcacaaactc
    27121 agtaaaaacg gacaggatat tccgtttgag accttccttg gctttgatgg ggataaggtt
    27181 cctgatattg acttgaactt ctcgggagaa gatcagccta gcgcccactt ggatgtgcgt
    27241 gatatctttg gtgaagaata tgccttccgt gcgggaacgg ttggtacggt agctgccaag
    27301 actgcctatg gatttgtcaa gggttacgag cgagattatg gcaagtttta tcgtgatgca
    27361 gaagtagaac gcctcgctca aggagcggcg ggtgtcaagc ggacaacagg ccaacacccg
    27421 gggggaatcg ttgttattcc gaactacatg gatgtctacg attttacgcc tgtccagtat
    27481 ccagcagatg atgtcacggc tgaatggcag accactcact ttaacttcca cgatatcgat
    27541 gagaacgtcc tcaaactcga tgtactggga catgatgatc cgaccatgat tcgaaaactt
    27601 caggatttgt ctggtattga ccctaatgaa attcctatgg atgacgaagg cgtgatggca
    27661 ctcttttctg ggactgatgt gctaggggta acacctgaac aaattggaac gcctacgggt
    27721 atgttgggga ttccagagtt tggaacaaat ttcgtacgtg gaatggtaga cgaaacccat
    27781 ccgacaacct ttgcggaatt gcttcagctg tctggtctgt cccacggtac tgacgtttgg
    27841 ttggggaatg ctcaggatct gattaagcaa ggaatagcgg acctatcgac tgttatcggt
    27901 tgtcgggacg acatcatggt ttacctcatg catgcgggtc tggaacctaa gatggccttt
    27961 accattatgg aacgggtacg taagggtttg tggctaaaga tttcagaaga ggagagaaat
    28021 gactatatcg aagccatgaa ggccaataag gtgccagagt ggtatatcga atcctgtggg
    28081 aaaattaagt acatgttccc taaggcccat gcggcagcct acgttatgat ggccttgcgt
    28141 gtagcttact tcaaggttca ccatcctatt tattactact gtgcttactt ctccattcgt
    28201 gctaaggctt ttgatatcaa gaccatgggt gcgggcttgg aggtcatcaa gcgcagaatg
    28261 gaagaaatct ctgaaaaacg gaagaacaat gaagcctcta atgtggaaat cgatctctat
    28321 acaactcttg agattgtcaa tgagatgtgg gaacgaggtt tcaagtttgg caaattagat
    28381 ctctaccgta gtcaggcgac agagttcctc atcgacgggg atacccttat cccaccattt
    28441 gtagcaatgg atggtctggg agagaacgtt gccaagcaac tggtgcgggc gcgtgaagag
    28501 ggagaattcc tctctaaaac agaactacgc aagcgtggtg gactctcatc aaccttggtt
    28561 gaaaagatgg atgagatggg tattcttgga aatatgccag aggataacca gttgagtttg
    28621 tttgatgagt tgttttaaaa aattgcttaa taatctatta aaagaggcta acgtatatcc
    28681 aatagattta cattagcttt cttttttgtt aaaatagtct atggaaagag ggtgagagta
    28741 tgtcaaagat gagtataagc atccgtctgg atagtgaggt taaggagcag gcccaacagg
    28801 tgtttagtaa tctgggaatg gatatgacaa cagctattaa tattttcctt cgtcaggcaa
    28861 ttcaatatca gggattacct tttgatgtta gactagacga aaatcggaag ttgctccaag
    28921 cgttaacgga tttagaccaa aatcgtaata tgagccagtc ttttgaatca gtctcagatt
    28981 tgatggagga cttacgtgct taagattcgt tatcataaac agtttaaaaa agattttaag
    29041 ttggctatga agcgtggttt gaaggcagaa ttattagaag aagttttgaa ttttctggtt
    29101 caagaaaaag aacatcctgc cagatatcgt gatcattcat tgacggcatc caagcatttt
    29161 caaggagttc gtgaatgcca tacccagcca gattggcttt tggtttataa agtagacaag
    29221 tcggaattga ttttaaattt gctgaggaca ggcagtcaca gtgatttatt ttaatctatt
    29281 ttaagggggt tctcatgaaa ctaagaatat ttgcggaaga taagccggct aagaaggtat
    29341 ttgaatatca attagaactt gctgatcgta caattcttct atcgacagca ctcttgtcag
    29401 gtgctattgc tttagcagga atcttttctg ctttgagaga aaaataaaaa tagaaaagag
    29461 aaaacagaat ggttttacca aattttaaag aaaatctaga aaaatatgcg aaattgttgg
    29521 ttgcgaacgg aattaacgtg caacctggtc acactttggc tctttctatt gatgtggagc
    29581 aacgtgaatt ggcacatcta atcgtgaaag aagcttatgc cttgggtgcg catgaggtca
    29641 tcgttcagtg gacagatgat gtgattaacc gtgagaaatt cctccatgcc ccgatggagc
    29701 gtttggacaa tgtgccagaa tacaagattg ctgagatgaa ctatctcttg gagaacaagg
    29761 ctagccgtct tggagttcgt tcatctgatc caggtgcctt gaacggagtg gacgctgaca
    29821 agctttcagc ttctgctaaa gctatgggac ttgccatgaa gcctatgcgt atcgcaactc
    29881 aatctaacaa ggttagctgg actgtagcag ctgcagcagg acttgagtgg gctaagaaag
    29941 tcttcccaaa tgctgcgagc gacgaagaag cagttgattt cctttgggac caaattttca
    30001 aaacttgccg tgtctacgaa gcagatcctg ttaaggcttg ggaggaacat gcagccattc
    30061 tcaagagcaa ggccgatatg cttaataagg agcaattttc agcccttcac tacacagcgc
    30121 caggaacaga tttaacactt ggtttgccaa agaaccacgt ttgggaatca gctggtgctg
    30181 tcaatgcaca gggcgaagaa ttcttgccaa atatgccaac agaagaggtc ttcacagcgc
    30241 ctgacttccg tcgtgcagat ggttatgtca cttctacaaa accgcttagc tacaacggaa
    30301 atatcattga aggcattaag gtgaccttta aggatggaca aatcgtagat atcactgctg
    30361 agaagggtga tcaggttatg aaagaccttg tctttgaaaa tgcgggtgcg cgtgccttgg
    30421 gtgaatgtgc cttggtacca gatccaagtc caatttctca gtcaggcatt accttcttta
    30481 acaccctttt cgatgaaaat gcgtcaaacc acttggctat cggtgcagcc tatgcgacta
    30541 gcgttgttga tggagcggag atgagcgaag aggagcttga agctgcaggg cttaaccgtt
    30601 cagatgttca cgtagacttt atgattggtt ctaaccaaat ggatatcgat ggtattcgtg
    30661 aggatggaac gcgggtacct cttttccgta atgggaattg ggcaaattaa ggagataata
    30721 tgttaggaag tatgttcgtt ggtctcctag tgggattttt agcaggtgct atgaccaatc
    30781 gtggagagcg aatgggatgt tttggaaaaa tgtttctcgg ttggatcgga gcctttctag
    30841 gtcacttgct ctttggaact tgggggccag ttttatcagg aacagctatt atcccagcga
    30901 ttttaggagc catgattgtt ttagctattt tttggagacg aggaagttaa tttcctaaat
    30961 ct
//
LOCUS       DAVBNZ010000022        30091 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000022 DAVBNZ010000000
VERSION     DAVBNZ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30091
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.022"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(83..523)
                     /locus_tag="VQ860_001037"
     CDS             complement(83..523)
                     /locus_tag="VQ860_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3119474.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLNGRGPVWWVPFEEMTAETRQAKPDEIRLPAKQNMV"
     gene            complement(525..1562)
                     /locus_tag="VQ860_001038"
     CDS             complement(525..1562)
                     /locus_tag="VQ860_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET3119475.1"
                     /translation="MNQTVEYIKELTAIASPTGLTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(1660..2985)
                     /gene="brnQ"
                     /locus_tag="VQ860_001039"
     CDS             complement(1660..2985)
                     /gene="brnQ"
                     /locus_tag="VQ860_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET3119476.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVIGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(3156..3248)
                     /locus_tag="VQ860_001040"
     CDS             complement(3156..3248)
                     /locus_tag="VQ860_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3119477.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(3291..3443)
                     /locus_tag="VQ860_001041"
     CDS             complement(3291..3443)
                     /locus_tag="VQ860_001041"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3119478.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(3603..4181)
                     /locus_tag="VQ860_001042"
     CDS             complement(3603..4181)
                     /locus_tag="VQ860_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET3119479.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(4235..5635)
                     /gene="pepV"
                     /locus_tag="VQ860_001043"
     CDS             complement(4235..5635)
                     /gene="pepV"
                     /locus_tag="VQ860_001043"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET3119480.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(5648..6253)
                     /locus_tag="VQ860_001044"
     CDS             complement(5648..6253)
                     /locus_tag="VQ860_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET3119481.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            6424..7224
                     /locus_tag="VQ860_001045"
     CDS             6424..7224
                     /locus_tag="VQ860_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3119482.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(7406..8203)
                     /locus_tag="VQ860_001046"
     CDS             complement(7406..8203)
                     /locus_tag="VQ860_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3119483.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLDAETDVAVYGHVHKQLLRYGS
                     QGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKVAYDYEAELELAK
                     SKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDFL"
     gene            complement(8193..10037)
                     /gene="uvrC"
                     /locus_tag="VQ860_001047"
     CDS             complement(8193..10037)
                     /gene="uvrC"
                     /locus_tag="VQ860_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET3119484.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(10077..10778)
                     /locus_tag="VQ860_001048"
     CDS             complement(10077..10778)
                     /locus_tag="VQ860_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET3119485.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(10857..12089)
                     /gene="murN"
                     /locus_tag="VQ860_001049"
     CDS             complement(10857..12089)
                     /gene="murN"
                     /locus_tag="VQ860_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET3119486.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(12094..13314)
                     /gene="murM"
                     /locus_tag="VQ860_001050"
     CDS             complement(12094..13314)
                     /gene="murM"
                     /locus_tag="VQ860_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET3119487.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(13426..14205)
                     /locus_tag="VQ860_001051"
     CDS             complement(13426..14205)
                     /locus_tag="VQ860_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3119488.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(14274..15935)
                     /locus_tag="VQ860_001052"
     CDS             complement(14274..15935)
                     /locus_tag="VQ860_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3119489.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILHESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(16110..18332)
                     /gene="recJ"
                     /locus_tag="VQ860_001053"
     CDS             complement(16110..18332)
                     /gene="recJ"
                     /locus_tag="VQ860_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET3119490.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            18609..19367
                     /locus_tag="VQ860_001054"
     CDS             18609..19367
                     /locus_tag="VQ860_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3119491.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAILSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     LDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            19378..20172
                     /locus_tag="VQ860_001055"
     CDS             19378..20172
                     /locus_tag="VQ860_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3119492.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDHSILSGYTSKRTALLDDSFKPSD
                     YSIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            20185..20862
                     /locus_tag="VQ860_001056"
     CDS             20185..20862
                     /locus_tag="VQ860_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3119493.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            20872..21531
                     /locus_tag="VQ860_001057"
     CDS             20872..21531
                     /locus_tag="VQ860_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3119494.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            21768..22892
                     /locus_tag="VQ860_001058"
     CDS             21768..22892
                     /locus_tag="VQ860_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET3119495.1"
                     /translation="MEFSMKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSL
                     TFILATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNL
                     AIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFL
                     VGSYALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQF
                     AFLKIFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYG
                     HMIIEEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYNFRGDENAVYLDLLRNY
                     AQKNPNFELHLIDSTKDGYLNFEQKKCPNMQPSICVVLFL"
     gene            complement(23290..24171)
                     /locus_tag="VQ860_001059"
     CDS             complement(23290..24171)
                     /locus_tag="VQ860_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET3119496.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(24312..25640)
                     /gene="vncS"
                     /locus_tag="VQ860_001060"
     CDS             complement(24312..25640)
                     /gene="vncS"
                     /locus_tag="VQ860_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET3119497.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKNRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(25637..26293)
                     /gene="vncR"
                     /locus_tag="VQ860_001061"
     CDS             complement(25637..26293)
                     /gene="vncR"
                     /locus_tag="VQ860_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET3119498.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(26342..26425)
                     /gene="pep27"
                     /locus_tag="VQ860_001062"
     CDS             complement(26342..26425)
                     /gene="pep27"
                     /locus_tag="VQ860_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET3119499.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(26606..27985)
                     /gene="vex3"
                     /locus_tag="VQ860_001063"
     CDS             complement(26606..27985)
                     /gene="vex3"
                     /locus_tag="VQ860_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET3119500.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTAHAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(28037..28684)
                     /gene="vex2"
                     /locus_tag="VQ860_001064"
     CDS             complement(28037..28684)
                     /gene="vex2"
                     /locus_tag="VQ860_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET3119501.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(28697..29974)
                     /locus_tag="VQ860_001065"
     CDS             complement(28697..29974)
                     /locus_tag="VQ860_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3119502.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         8606 a         6917 c         5594 g         8974 t
ORIGIN      
        1 aaaagtggta cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact
       61 tgcttcatca ttcatagaac tactatacca tattttgttt cgcaggaagt ctgatctcat
      121 ccggttttgc ttgacgggtt tctgcggtca tttcttcaaa agggacccac cagactggcc
      181 cacgtccatt gagaccgtga ccattcatgt cacctgttcg tctaggaaac agatgccaat
      241 gaagatgggc atcgccattt cctagcagtt cgatattcat tttctcagca gcaaaggcct
      301 tggcaactgc ctcttggacc acactcattt cttctagaaa acggagtctt gtctcctttt
      361 tcaaatggtg caattccgtg acatgttcct tggctagaaa gagactatag cctgcaaaat
      421 actgatggtc tccaatcaca agatagcctg tttccaactc tttgacaaag tagggatttt
      481 ctcccttctt gatgagctca attctctggc aaataaggca catatcaatc tactaaattg
      541 cttctaagat aggcatcgac cattcgttct gttgcgacca ccgagtcaat atgagtgcgc
      601 tcataagaat gactagactc gatacccgca ccaagaaggg catgcttgac ctctgcccct
      661 gcagacatag ccgctgaagc atccgaacca taaaatggat agatgtccag cttaaaagga
      721 atatcttgct ctttagccaa ggcaaccaag tgttgacgga agtcatagtg ataaggacct
      781 gaagcatcct tgacacagat agatactgtg tactcatctg tctgctggtc atctcccata
      841 gctcccatat ccacagccag atattctact acctgagcag gaatgttaga attagcacca
      901 tgtcctactt cttcaaaaac tgaaaaagca aaatgagttg ttactggcaa ttcaatcttc
      961 tctttcttat aaatacgaag caggttgagc aaaatcgctg cgctgacctt atcatccaaa
     1021 tgacgagact tgataaaacc tgtatcagtc acaacagttc gtggatcgaa gctgataaaa
     1081 tcaccgacct caatcccaag agcacgagtt tctttttcat tgcttacttt tacatccaaa
     1141 cgcacttcca tattgtcctg cgtgcgttct gcagttcctg catccttgta gacatggcaa
     1201 gaagtttggt ggatgaggat ggttcctgat accttttgac ctgtgctagc cacatgaacg
     1261 gtacagtttt caccttcaat catgttccaa ggaaaaccac cgatacggtc caatttaaga
     1321 cgaccatctg gtttgacagc acgaacaata gcacccagcg tgtccacatg ggcagtcaca
     1381 tagcgatgtt gctcatcatt ttgacctttg atggtcacat tgacaccacc cttggctgtg
     1441 cgaactggct ggtaaccaaa accttctaga gtcttgacta aataattcga aatttcacga
     1501 gttaagcccg ttggcgatgc gatggctgtc agttctttga tatattctac tgtttgattc
     1561 atttcttcac ctctttcgct acctattata acacatttat catcggataa aaaaagaaaa
     1621 tcactcctgt agacttggct acaaaagtga tttaagtgat tattccattt caaaaacatc
     1681 gctttcttgc ttgtttggta gaaccaatga gagcaagatt ccaacaatgg ctggcaccaa
     1741 ccatgggaga gatgccttgg caaaaggaag aacgctaaca agatttgcaa gaaactcaac
     1801 cttaaacgag cttcctagta cgcttgcaat ggcaataact gtaaccacag caattgtcaa
     1861 ctgcatacct ggttttgaaa gggcaacaaa tttgttgaca atgacaatca taacgatagc
     1921 aatcgtgatt gggtacaaga taaccagtac tggaattgag tacttgataa tcgcatcaag
     1981 acccaaattg gcaatagcaa atccaatcaa ggtaaaggct gtcgcataaa ccttgtagct
     2041 gatttgtggg aagcgctcat taaagaactc agctgttgac acaatcaaac caacagtcgt
     2101 tgtgaagcag gttacggtaa ccatagctgc aaggaagagt tgagctgttg agccaaagat
     2161 ttcttgagtg gcttgtgaca agatgtaaac acctggtgtt ccacccttca tcgcttcagc
     2221 tggtactggg aaatgatttc caagaaaacc taaaccaatg taaagagcgc tgaaggcaag
     2281 ggcaacaacg ataccaataa cccaaatagt tgaaatgtat tctttcttac ttgaaaatcc
     2341 aagttgtttc aaggtttgaa ctgcgattac gctaaaggcc actgaggcaa gggcgtccaa
     2401 ggtattgtaa ccttctagga aacctgtacc aaaggcagaa gcttgataag cagctgaagc
     2461 agcttgagga cttgttccac catatttgat agctcccaga acgaccaaga taacaatcaa
     2521 aattgcaaag actggcgtta aaatacgtcc aatgcggtct aagatttttg atggattaag
     2581 cgaaatcaaa taggctgccg caaaatacag aaccgtaaat acaatcaagc caagtccttt
     2641 atttgcatcc gacaaaaggg ggctaatccc tacttcgtaa gctgttgtag cagtacgtgg
     2701 ggtagcaaag aatggaccga ttgacaagta aagaactgag aggtaaagag tcgcaaacca
     2761 aggcgctatc ttcgttgaaa tctcgtagat atatccttta ggatttagcg ttccaataat
     2821 aagggtcaag acggcgatac caacgcctga aaagacaaaa cctgcgatgg caggaagaaa
     2881 atgttctcca gatagagcac ctagagaagg cggaaaaatc aagttccccg caccaaaaaa
     2941 tattccaaac aggagcaaac ctgttagggt acctttttta gccataaaaa tctccttcat
     3001 atttataaaa tactgaccta gtataccacg attaggagtc tgaaaaaagc atcacgaggc
     3061 aaatattaaa tgttttcaat tttcttaaaa ataagaatta tctaaaaata aaactctcct
     3121 acccagtcca caccaagtag gagaaatgca aaattttaaa gttcttcaaa ggctaacatg
     3181 ccaccctgga cattgataac attataacct tgttctaaca ggaattggca agcacgcgcc
     3241 gatctcattc cagatttgca aataatataa tgcaagcgat ctttgtccaa ttaatcataa
     3301 ctatcagcca attgactaag cggtaggttg tgggcacatt ctaaatgaag agctgcaaac
     3361 tcatccactt ctctcacatc cactagagaa agctggtcgt tttggtaaag ctggtaaaat
     3421 gcgtcaaagg ctatttcttt cattcttttt cttctaatac tcttcgaaaa tctcttcaaa
     3481 ccacgtcagc gtcgccttac cgtgcgtatg ttaccgactt cgtcagtttt atctgcaacc
     3541 tcaaagctgt actttgagca gcctacgact agcttcctag tttgctcttt gattttcatt
     3601 gactataaaa tggttttaat tctttttttc aaatctggca ctacttctgc ctcaaaccaa
     3661 ggatttttgg ccatccagat ttgatttcgt ggtgatgggt gaactagcgg aaaataggct
     3721 ggcagatagt ctttatagtg tttcaccctc tccgttacct tcccactgat tttctcctgt
     3781 aaatagtagg cttgggcata ttgcccaatc aagagggtta actgaatatc aggcaattcc
     3841 tgtaagagct gcggatgcca tttttctgca aaacctgtac gaggcggaag atcacccgac
     3901 ttgccatgtc ctggaaagta gaaatccata ggcaaaacag caaaataacc tgaattgtaa
     3961 aaggtatctt catccacacc tagccagtcc cgcaagcggt caccactttt atctttccag
     4021 taaaggcctg cttcttgagt tttaagtccc ggagcctgac cgatgatatt gatgcgagca
     4081 gtttttggcg ctgcaaagag aggctcaatg ccacgctctg tatagctggc attctgtgaa
     4141 tccgccatga tagcctgttt gattctttcg atttgagaca tctactttcc ctccaaaaag
     4201 aagtccaagc ataagatctc agacttctat cgttttattt gatcaattcg taaatagctt
     4261 cggcataaat tgctgctgct cggaaaagat catccaaggc gataaattca ttggcttggt
     4321 gcatggtatc aatcgagtct gggaacatag caccgtaggc aactccgcgt tctagcaagc
     4381 gaccaaaggt tccaccaccg atgacttgtt catgaccttt aaggccagtt tgtttttcat
     4441 agatattcaa caaggtttgc acaagtggat cttccattgg cacatagtga ggcgtgtgac
     4501 cgtgttcaga caggctaaca gaaacaactg gcaagttttc aaggattgac ttgatttgtt
     4561 ctggacttgt tccttttgga tagcggatgt tgagggcaat ggtattatca gcacttgttt
     4621 catcgaagcg gaagacgccg gcattcatag aaagagcacc catcttttca tccacatgag
     4681 caatcttaag attttcaccc tcatgatcgt tcaagagaat tttacctgcg atgtcaaggt
     4741 agtctttggc tggaccagca aagccaaact ggctgaggaa gagggcaagg taagttgcgc
     4801 cattgacacc tgaagcaggc atagcaccgt gggctgattt accaatgatc gtcaccttgt
     4861 atttgccagc ttcttcttgg agttctcctc taagtttgtg ttctgcaaca aaggcatcta
     4921 gtttagcttg caagtcagcc aaatcacctg aaacgactgc tgttgctgat tctggtacca
     4981 tattttcacg taaaccacct gtaaagctgt gaagacgggc agcacctgta ttttctcctg
     5041 caaagtggag gtattccgtg atatttcctt tttcaccatt gatgattgga aattcagcat
     5101 ctggagagaa accgaaatct ggtttggcaa gtcctacgtg ctcaaagtag tagtccatgt
     5161 ctgcccagcc tgattcttcg tctgttccaa cgatgaagcg aactttctta gaagttggaa
     5221 gacccaattc tttgatgatt ttcaaaccat agtaacaagc tgttgtagga cccttatcgt
     5281 ccgaagcccc gcgcgcataa aggcgaccat ctttgatagt tggtgtgtaa ggatctgtgt
     5341 cccaaccgct accagcaggc accacatcca tatgggcaaa gattccgaga acttcttctc
     5401 catcaccaaa ctcaaaatgt cctgcgtagt tatcgacatt cttagttggg tagccatcgc
     5461 ggtctgcgat ttcaaggaat ttctccaagg cttttactgg accaggtcca aatggatgct
     5521 gggcatcagc cttgctatca tcacgttctg agttgatttc caaaaggcta aacaagtcag
     5581 ccaagaggtc ttctttgcgt ttttctactt ctgctgtaaa atcaattgct gtcatttttt
     5641 cttctttcta tcttttctcg atgatttcat ctactggcaa gcggtagctt ggttccaatt
     5701 tgtcgtctgt gtaacccact gtgatcaaga gttctgggcg gaaacggtct tcgatttcca
     5761 aaacttcatt aacttttgat ttgtcaaaac caaggataat attggaacca attccttggt
     5821 ctgtaagagc gagaaccaag ttcatagcaa ccaaacctgc attgagtgct aggtagtcgc
     5881 tgacttgttg ttcattgtag cgtgcaaatt cagctggcaa atttttcatg aagtattgaa
     5941 gttgctcttc agaaaagtta ttagcaccac caacacgggc aatcttacga gcacgtttgg
     6001 ctaagtccgt atctgtaaac aaggcaatgg ttacaggcgc tgatgatacc tgttcaaaat
     6061 tggaaccata agctaacttt gccagttcag catttttctc acgtaccacc acaaatttcc
     6121 aaggctggct gttgtgggcg cttggcgcca aggttgcaat ttcgatagcc gtacgcacat
     6181 cttttggatc aacaggctta tcagtaaaat gcttagtcgc atgacgtttt ttatttaatt
     6241 caagaaattt cataatcgat ttccttttct aattctactg cttccattct accataattt
     6301 gaaagagctt gcagggattt ttcatgatta agtttttcta tcacagacat aaaagatata
     6361 tattggttta tcaggaacat ttctgataaa ctagcaagta ctttacattt gaatggagac
     6421 agtatgaaaa aatttagcct attactagct atcctaccat ttttggttgc ctgtgggaat
     6481 caagctacac ccaaagagac tagcgctcaa aagacaatcg tccttgctac agctggcgac
     6541 gtgccaccgt ttgactacga agacaagggc aatctgacag gcttcgatat cgaagtttta
     6601 aaggcagtag atgaaaaact cagcgactac gagattcaat tccaaagaac cgcctgggag
     6661 agcatcttcc caggacttga ttctggtcac tatcaggctg cggccaataa cttgagttac
     6721 acaaaagagc gtgctgaaaa atacctttac tcgcttccaa tttccaacaa tcccctcgtc
     6781 cttgtcagca acaagaaaaa tcctttgact tctcttgacc agatcgctgg taaaacaaca
     6841 caagaggata ccggaacttc taacgctcaa ttcatcaata actggaatca gaaacacact
     6901 gataatcccg ctacaattaa tttttctggt gaggatattg gtaaacgaat cctagacctt
     6961 gctaacggag agtttgattt cctagttttt gacaaggtat ccgttcaaaa gattatcaag
     7021 gaccgtggtt tagacctctc agtcgttgat ttaccttctg cagatagccc cagcaattat
     7081 atcattttct caagcgacca aaaagagttt aaagagcaat ttgataaagc gctcaaagaa
     7141 ctctatcaag acggaaccct tgaaaaactc agcaatacct atctaggtgg ttcttacctc
     7201 ccagatcaat ctcagttaca ataacactct tcgaaaatct cttcaaacca cgtcagcttt
     7261 atctgcaacc tcaaagctgt gctttgagca acctacggct agcttcctag tttgctcttt
     7321 gattttcatt gagtataaga tatactaaaa gcgattggac cagccaatcg cttttttagt
     7381 ttgcattggc tattttagga aactcttaca aaaaatcaaa aaaattcttc acatcctcta
     7441 catacccatg cttttctatt aagctggcta ataattccag attgtgcccc tgatagttat
     7501 cgtcacgacg cagttcttca tacatttcga taaagggaag ccccttggac ttggccaatt
     7561 ctaactcagc ttcgtaatca taagcaactt tacgaaattg gatattgagt aattccccat
     7621 cttcaacttc tatcacggca tactgggcac ggtgattttt taacgcctcc caattaaaat
     7681 agggcatgcc aatcgaccct ggattgatga tttgttgccc ttgacttcca taacgaagca
     7741 actgcttgtg aacatgacca taaactgcca cgtccgtttc cgcatctagc aagtcaccac
     7801 catagttttt gtcaggtaaa ttatgagaga tagaaaagcg caatccgtca atttctttct
     7861 tttccagcaa aggcaagctt cgtagccaga caatcgttgc aggatccatt cgctccatca
     7921 aatactgtgt catacgcaag agctgaactt cctgtgggtc ttctaagcca tattgcccat
     7981 ctaaagcctc aaggacacga tcatcccaat tgcctcgaac acttgctgtg ataggaaggt
     8041 cctttagcag ggcgactaag tcatttgcgc ctggaccagg aagaaaaata tctcccagaa
     8101 gccaatattc actggcccct tgatttttag catctgcaat cactgcttct agcgccgtcg
     8161 cattgccatg aacatctgat aaaattgcga ttttatggtt cattgtggtt tccttccgtt
     8221 tggtaatcta ctctttcttc tgctacttga ggcaaggctt ctccctgcgg gttcaacttt
     8281 ctttgcacag cctctgcaac gactctaggt accccaactt cgacaatctc atccacactg
     8341 gcttccttga ttttggtcaa agacttgaaa tgcctcatga gattttgctt gcgtttaggt
     8401 cccagaccat caatcccatc caattgagat gagaaagaat ttttggagcg cagttggcgg
     8461 tggaaagtga tagcaaagcg gtgcacctca tcttggatgc gttggaggag gaaaaattcc
     8521 tgagaattgc gagacaagtc caccacctca agcggatctc caaagagcaa ttcatgggtt
     8581 tggtgcttat cattcttttg cagcccagca attggaatat ccaagcccag ttcctcttgg
     8641 ataacctgct tagcgatatt gacttgacct tgccccccat caatcacaat caaatctgga
     8701 ggagtcaaag cctcacgctg tactcgacca tagcgtctgc gaatgacctc tctcatgctg
     8761 gcatagtcgt ctggtccaac aaccgttttt atcttgtact tacggtaatc cttcttactc
     8821 ggtttaccgt tgacaaagac caccatagcc gaaacagggc tagttcccat gatattagag
     8881 ttatcgaagg actcgatacg tactggggtc gggatttgga gcaaacgccc tagattttca
     8941 atagctcctt gagtcttttc gacagatttt tctagcagat tgaacttctg ctctagacta
     9001 acacgagcat tttttatggc tagattgacc agttgttttt tctctccacg ttgaggctta
     9061 agaatcttgg aatccaccaa ggccttgaca gcctcttcgt caatatcctg cggaatcagt
     9121 acctcattgg gaactagatg agatttttct tgatagaatt gtcctacata ggtcaaaaaa
     9181 tcctcatctg gatcattgaa gtaggggaag agattgacat cgcgctcgat aagcttaccc
     9241 tgacggacaa agaaaacctg cacacacatc cagcccttat ccacatagta gccaaagaca
     9301 tcgcgatttt gcaaatcttt cgccatgacc cgttgcttgg ttcgaagcgt tccaatagcc
     9361 tgaatcaggt cacggtattc cgccgcacgt tcaaactcca tactttgtgc tgctactgcc
     9421 attttactct tgagatcatc gatgattttg tcatcctgac ctttcagaaa atcagacacc
     9481 tcctgagcca tagacttgaa ataagcctca tccttcttac agatggtgtg ggccatacac
     9541 tggccgatat ggtaataaaa acagacctta gagggcgggt tggtacattt tcgaaaaggg
     9601 aaaatcctat ctagaagtcg cttgatttca ttggctgccc ccacatctgg ataagggcca
     9661 aaataaagac caccgtcctt tttgacctga cgagtaatga taagccgtgg atagcgctca
     9721 ttggtgattt tgatgaaagg ataggacttg tcatccttga gcatgatatt gtacttgggc
     9781 ttgttttcct tgatcaggtt gatttctagg agaagtgcct caatattaga ctccgtaaca
     9841 ataaattcaa aatccacaat ttcagacacc agagcctctg tcttggtatc atgacttcca
     9901 cgaaaatagg accgtactcg attacgcaga tttttagcct ttcctacata gataatggtg
     9961 ccatttttat ccttatgaat gtagcaacca gggctggtcg gcaagagctc tagttttgat
    10021 ttaatcaagt tgttcatagt tccattatag caaaaaaagt agggaaagat agtaccctac
    10081 tcactagtct catatatttt tcggaggttt gcaacatcct cttcctggat accataaaag
    10141 gaacctgctg gttgcatgac agacttctca tctgtatggt ccaagccaat cgcatgacct
    10201 aactcatgtt ctgccgtatg gacaaggcgt tcataggagt agccatagta tggattggac
    10261 aaataataat gattcaaccg caccgttacg gacaagaatt gccctgttaa gagattagtt
    10321 tgactttccg cctctcctgc cacaggagtg cctccgtcgt tcatctccgt agccgtaata
    10381 tccgccttac tagactcagt cacgagttca aagttaaaag caccagtttg attccagttc
    10441 tggattgctt ctaaataagc ctcttgaaag cgtgaatcca tctgcggatc caggtaaata
    10501 cgagcagagg cctgtgccca ccttccttca gaatgctggt gactatctgt ctggcttaac
    10561 ttaggcagtt gccctgtttt ctcccattgg tcaatacttt gttgaccaat ttttactgac
    10621 cgttctgctt gctttagcgc tccttgaaaa tccccgttca gataccagag aagtccgaaa
    10681 gcaagcacac ataagagcac aactatccaa accagacgcc aaaacaaacg ccacacaaaa
    10741 gaaaagaaag cccctatcaa acgaaaaagc cagcgcatgt ctctccacct ttctagcaaa
    10801 taagaattat tttactaaaa gaagctaaaa gaaatctaaa tactgacttt ttcatcttaa
    10861 cgtcctacta tttttttgag taactggata gctttgtatt ttaaaggcga tggatggtaa
    10921 cggaaagtac ccgctttgcg tacaatatag ccattaaaat tctgtttaaa acgcaaaaca
    10981 ccatcacttc catcaaaaat cccttgaatg cctaggaagt tgtatttagg tattccacgt
    11041 tttatgcttt ccaacataac atatttttga agcagggcag gggcatagaa cttattaaac
    11101 tcagtgtagg aaccactaaa gagataagtc gtttcctgag gcatataaac aaataaactc
    11161 ccagctaaaa caatatcttc ttctccatat ttttcaatca agtctcgcgc ttctgctttt
    11221 cgaacttcaa acgtttcaaa ttgactagaa tattctctca gttgattttg ttttttctca
    11281 gaatgaggat ttttactcaa atcaagtcgc aacttgtcca agttttcttc tagtttactt
    11341 tgttcacctt gcaatttgct catatagtcc gaaaaattta agcttgctat gagaaactcc
    11401 gcttgttctc caaaagtatc ataaaaatgc tcataatatt ctaaactttt atcactatat
    11461 tctctacgtt cagaggtttc ttttgttata ttcttaaaaa tcgatagttc ttcacgtttt
    11521 aactttttca accgaatgcc aaaggtttca gcctttttca ccaagggttt accctttttg
    11581 ctaaaacttt taagcaaact cttttcagtt aattcagtta aatctttata gtataaccaa
    11641 tctggttctc cacctgggta acctgttgtt aagccatcaa attgataacc taaatcagtc
    11701 aaaccttgaa taatactttt tttctcagca tctattggat taccttggct atcaaaagtt
    11761 tgataagttt cataaggttt tacaagcaac tctaatacac cattttgctt ggcatattct
    11821 tttaactctg cataaaaaac tggaagagca tcttgttggg tataaatcgg ccccgaattg
    11881 agttccatat gcagaccacc cagcatgggc aagctataaa ccagagctgc aacttgaatt
    11941 tctccttctt gtttcaaagc aagataaaca attcgagccc ctcttttttc tagcaaatcc
    12001 cccatctgga cagattgcat aaaggaacga gaagaaacct gatcagaata agtctgaaac
    12061 tcttctttcg tgagtgttgt tagtgccata tacttacttt ctatgttttt ttcttaatgt
    12121 tttacggaaa tcaagagcaa gtcttaacag aggatagaga ggatgagtgg gcattgtaaa
    12181 ttcacccaag tattcttcaa tcgttggatt aaatttttcc ttaaaatgat aaagtccacc
    12241 attgagagag ttttcaacac cacctaaatt ttgccaaacc atacctcgct caaaggcata
    12301 gcgagccgtt tcataccatg ttaaaattgg tgcattgtaa cgtttaaaat catcatccat
    12361 accagcatat atattgacag aggtagtacc aaattccaaa ctcaaagtag ccgctaaagg
    12421 aactctcgct tgacctacat ctatatattc ctgcaagaag gtcaattcct ctaacaaacg
    12481 ttctttttcc ttcttctgcg cttctacttt tgaaattcga gtcgactcag taaaggtctc
    12541 ttccaaggct ctattttttg ctaactgttc ttctaattct tgcgaacgtt tagaaacatc
    12601 caaggtggcc aaggtgatat aggccttgtc cttaaaatta tctaacaatt ttttataata
    12661 ggcttcattc ctcaaatgaa tctcttttcg cttctcagtt tttttcatca actccgaaaa
    12721 tgaatctaat agttccagtc caccatattg aatctcaagc cctttgtttc gtgctgttcg
    12781 aatagcctgt tttgttgact tggaaagttt atcttcttca aaattttcct tgtatatttt
    12841 cgcctgaata cgaggttgaa tggtgtctcc catttcctcc gtttttcctg accaccttac
    12901 tcccatttgt tgcaaactat caataatagc cagattttca ggaaattctg tcttttcctg
    12961 attgattaaa ctttgagata ggcaaatact tgggtcaaaa gtcacaaaaa ccgctctctt
    13021 actgcgagca taggacttaa tagactgaat gacaaaattc aagagttctt tatccccata
    13081 atccaatata ggtcctcttg ggatgtaaaa cattttatag cctagcggaa gagttctaat
    13141 caaaatacta gctgtcgcca gtaatttttc ttccctgtaa acaccaaact tctcatgttg
    13201 ccaattagac ttaacttcct cccaagcact actttgtaat acattggcta attcatgttc
    13261 tttgacaaac tgatcatatt ctaatgtggg aatgccaatt tgataacggt acatttccta
    13321 ctctctttcc tccagtattt tattactatt ctactacttt cgtttgaaaa gtctagtgaa
    13381 aacatatttt attttagttc tactccccct atgctgaagt tcaaactaag tcagtctctc
    13441 ttctaatttg aaatcaattg gtagggttgt taaaaaaact tccaattgtt tttcccagta
    13501 gtaccactcg tgagttccag cgctatggct ataggtcaca tcaaaaccta gttttttgag
    13561 atttttcact gcgagattat tggcttcgta caagaaatcc tgttcgccac accacgccca
    13621 aagtttggtc tttttatccg attttttagc cagactttca agagaatagg gactagttgt
    13681 ccagtcttta atctctccaa aaacacctct ccagtaggct ggacttccca gattttgact
    13741 ttcaggagaa aagttttgaa aactgagggc acctgaaaag ctagctgcat gagaaaaacg
    13801 atttgtcgca agagccagtt tgaagcagcc gtagcctccc atagaaagac cagcgataaa
    13861 ggtcttttca cgcttgctag tcatattagg gaagaagcgt ttcagaacct gtggcaattc
    13921 ctctgctaga gccgtgtagt agtcaaaacc atactgggta tcggtgtacc aaccattgct
    13981 ggtattgggc ataacaacga tgagattagt tcctcgaagc aagcgttcta cattggtccg
    14041 cttaagccaa ctattatgat ttccagacat cccgtgcaaa aggtacaaga cgggaatatc
    14101 ttcacactct ggttcttcca ctcgattggc atcagggtag aggacattca ccccccactc
    14161 catatccaat acttgtgagt aatactcgat tttcattact gccatgattt tctccttcta
    14221 tttttctata agaaaaagcc gaaactcgac tttctctctg tttatttcaa cgattatttt
    14281 gcttccatga ctactggtaa aatagctgga cgacgcttgg tttggtcaaa gagatacttg
    14341 gtcaaattat ctcgaacctt ccctttaaga tctgcccagt caaagtcatc tccttgaaga
    14401 tactcttcta ccgtttggtt aatcaattct gaactttcat ggagaatatc gcgactcttc
    14461 ttgagataaa caaatccgcg cgtatgaaca cgagccctag ccacaatttt cttctcacga
    14521 cggttgactg taatagccac gatgaaaatt ccatcctctg acaagacctt acggtcacga
    14581 agaacaacat ttccaacatc accaatggca ttcccatcaa tcaagatatc tcctgctgaa
    14641 accgatccag ctggaacaaa gtctccattc tcgtaagcca tggtcgtccc ctttttagga
    14701 atgaagatgt gttctggcaa catcccaact gccatggcag ccttagcgtg agcatccaac
    14761 tcacgatact ccccttggac agggaagagg tacttaggtt gcaaaagatt gatcatcagc
    14821 tgcaaatcac gcacatttcc gtgccctgat acatgtaaac tttgggtaat caatttgaca
    14881 accccacctg cctgataaat catattttcc acacgcgcaa caaaggcttc tttagcaata
    14941 gacggagccg tagcaatata gaccaggtcc ccatccttga tttctacata acgatggcga
    15001 ccaatcgaca tcttacgaag tccattgata ggttcaccca tacgacctgt ctcaagaata
    15061 atcaactcat ggtcttcaaa gcgagacata tctttaggct taatcaagag aatttcgttg
    15121 gctaaagaca acttcttaag acgaatcgct gtgcggacga tattttcaat atcaaatcct
    15181 gtcaagacga tacgtcgacc tgttttatcc gcagcgtcaa aaatctgctg aatacgagaa
    15241 agattactgg aaacagctgc aacgatgata cgaccttccc agtcagcaat agtttgggta
    15301 atttcatccc taacttcact ttcactagcc acctgaatat tgctgtctgc attggccgaa
    15361 tcactgagga gagccaggac gccgtcacga ccaatctctg ccaaacgagc aaaatcagtt
    15421 gcataagatt cactagccgt ttggtcaaat ttgaaatcac ctgtataaac gatgcttcct
    15481 tccgatgtct tcaagacaat tcccagactc tctggaacgg agtaagtcgt agggaagaag
    15541 gaaaccactg tcccaccaaa atcaatctcc gtattctcat caatgacatg gaaatcatta
    15601 aatttcttaa cggcatcatt tcctttgaca aagagctttg ccaactcaat ggtcaactca
    15661 gacccaaata caggaacttt agcctctgcc aagagataag gtagagcacc aatggcatcc
    15721 gcatgcccgt gggtcaagaa aaccccagca atacggtcgc tattttcaaa aaggtaatcc
    15781 atgtttggaa tcaccacatc gacccctaat tgttcatttt caggatattt taaccctaca
    15841 ttcaaaacaa aaatggactc tccaatttca gcaatgtaca tattttttcc attctcacgc
    15901 acaccaccaa gtgttgttaa actgatatta ctcatttttc ctccaaaatc ttagtttatc
    15961 ttgattatag ggcaactcta ccctcttatt ctaaaagttc taatactttc agccgaatct
    16021 tttcctacca ttataccatt tttttgatga ttttcaaaat gaaggtctgt tttcaaaaaa
    16081 gagttgattt cccaactctt tcctaacttc tactcttttt ccatcaaaaa atcataaatt
    16141 tcttgcaccg tacccagcgc catcatttct tggtctttaa cggtttgttt gagattttgg
    16201 taaatttgac tttctcctat ctcccgcttt ggcgcctctt tattgactgt catcacacca
    16261 tcttttatcg tcacaaagcc tagttcttca aatacttgaa tcatcttgac cagcaagatt
    16321 tgttgaatat taagatatgc agccaaatct ttcagcttgt agcgaatatc aaactctggg
    16381 aactggtaaa tagtcttgta caatttggca aactgatctc tagtcccata acctgtcaga
    16441 taataggcct tgtcaatatc atttttgaaa tagacagcag agaaatgctg ttcctgaaaa
    16501 atggtcttca gctgagtaat atcctctgga atgtttttta cgacaatagc ttcactagcc
    16561 gcaagatttg gcagttctcc aggaaaatcc aagactggaa caccttctgg caagactgca
    16621 ttttttccac gaatgttaaa aagttgaaca ccttccactc gcgcatccac catcatcaac
    16681 tggagggcag tttggccatt ccattggttg acagacaatt taaccgctaa ctctagattc
    16741 ttggtttgag aaaactctgt cgcccatctg ccttgaccaa aggctaccac ttcaaaactc
    16801 gcctcaccct tggaaatttt cagctttaga tgggcattac ctgcccccat agtacgagca
    16861 ctttcgacct gaaaattctt gatataaaaa ataggtttct gattatccat tccaaaagga
    16921 gctaaacgtt caaaactttt gaccgtttcc aagctaagtg cctccaaatc caactcttca
    16981 tctaggttta acttattctt gccaccagca tctgcacctt tttcacgaac ataatcttcc
    17041 aaaacctgag ataaatctga gagttgctca acttccagcg tcatacccgc tgcacctgca
    17101 tgacctccaa aggcgatgaa gaggtctcga tggggatcca gagcttcaaa aatatcgacc
    17161 gcttccacac tacgagcact gcccttggca cgaccgtctt ctatattaag aacaatgact
    17221 gtctgtccca attcttccaa taaacgacca gccacgattc ctagaacccc aggattccag
    17281 ccttccttgg ccaagacctg aaccttcttc tcaggatcca ccatggtctt ggcttcttca
    17341 tagatagact gaacgatttc cttgcgctct tcgtttttct ggtgaatcat aagggcaatc
    17401 tcatgcgctt cctcatcatc aaatccagtc aacaaatcaa tggcaggatt gggatcatcc
    17461 aagcgaccca aggcattcaa acgaggagca atctggaaac caaccgtttc ttctgttact
    17521 tcgttggcag caatcccagc catgtccagc atttcttgca gaccaatgcg ctgggtatga
    17581 cccaacattt ccagaccata ttgaactaag atacgatttt catccgtcag actcaccata
    17641 tctgcaatag ttccaatagc gaccaaatca agcaattcca cttgcacttc ttctaacagg
    17701 gcacaagcca acttgaaagc aactccacaa ccagccaaat atttaaaagg ataatccgca
    17761 tctggatgtt caggatggac aatagcataa gcatctggca gggtttcagg catggaatga
    17821 tggtctgtca caatgacatc tactcccata gactgagcca atgcaatagc ctcatgacca
    17881 gcaaccccat tgtccaccgt cacaatcaag gaaattcctt cttgctcgat aaagtattta
    17941 taaacactag cattagggcc atagccatcg gtaaaacgat ttggcaggta aactcggcac
    18001 tccgcaccaa gttgttccaa actttccttc acaatagaag ccgaagtcat gccatccgca
    18061 tcatagtctc cataaacgag aatattttcc ccttcttcaa tagcctgacg aatccgctcc
    18121 actgccttgt ccatatcatg gagcagataa gcatcatgta agtcctccaa ggaaggttct
    18181 aaaaacttct tcagactttc ttggtcctga atccctctct caaacaataa ccgagccacc
    18241 tcaggaccca gtccagcctt cttggctatc tttgtaaaat ccgcatcttc tacctgcagg
    18301 gcaaactgcc attcataagt aggtgttatc aaaaagacat ccactctttc taagaattct
    18361 attgcttcat tataacatga tttagacgtt ttctctatcc agattgcttt tttataacat
    18421 tttatagtat attgaaacta gaatagtaca cctctactta taaaatattg ttagaaatcg
    18481 atttgactgt cccgatcgat ttgtcctttt cttatttcac tatagtgaat tttttcagat
    18541 acggtttgac aagaacattc ttttattgta gaattgtgtt ataaaatcta atataaagga
    18601 gatctctcat ggctttagta gaatttaaaa acgtcgaaaa atattacgga gactaccacg
    18661 cactccgcaa catcaatctc cgttttgaaa aaggacaagt tgttgtcctg cttggacctt
    18721 ctggctctgg gaagtccact cttatccgta cgatcaatgg tttagaggct gttgacaaag
    18781 gaagtctcct agtcaatggg caccaagttg ctggtgccag ccagaaagat ttggtacctc
    18841 ttcgcaagga agtcggcatg gtttttcaac attttaacct ttatccacac aaaacggtgt
    18901 tagaaaacgt gacacttgcg cccattaaag ttctaggaat tgataaaaaa gaagctgaaa
    18961 aaaccgccca aaaatatctg gaatttgtaa atatgtggga caagaaagat tcctatcccg
    19021 ccatactatc tggtggacaa aaacagcgga tcgccatcgc tcgtggtctt gctatgcatc
    19081 cggaactcct cctctttgat gaaccaacat ctgctcttga tcctgagact atcggagatg
    19141 ttctagcagt tatgcagaaa ctggcgcatg atgggatgaa catgatcatc gttacccacg
    19201 aaatgggctt tgctcgagag gttgcggacc gcattatctt tatggccgac ggagaagttt
    19261 tattagatac gacagatgtc gataactttt ttgacaatcc aagcaaacct cgtgcccaac
    19321 aattcctcag caaaattatc aaccacgaaa gtgacaaagt caaataagga ggcgcctatg
    19381 aaaaaaaaat tctttttatc agcattattg attagccttt tcggccttgc tgctgccaaa
    19441 ccagtccagg ctgatactag tatcgcagac attcaaaaaa gaggcgaact ggttgtcggt
    19501 gtcaaacaag acgttcccaa ttttggttac aaagatccca agaccggtac ttattctggt
    19561 atcgaaaccg acttggccaa gatggtagct gatgaactca aggtcaagat tcgctatgtg
    19621 ccggttacag cacaaacccg cggccccctt ctagacaatg aacaggtcga tatggatatc
    19681 gcgaccttta ccatcacgga cgaacgcaaa aaactctaca actttaccag tccctactac
    19741 acagacgctt ctggattttt ggtcaataaa tctgccaaaa tcaaaaagat tgaggaccta
    19801 aacggcaaaa ccatcggagt cgcccaaggt tctatcaccc aacgcctgat tactgaactg
    19861 ggtaaaaaga aaggtctgaa gtttaaattc gtcgaacttg gttcctaccc agaattgatt
    19921 acttccctgc acgctcatcg tatcgatgcc ttttccgttg accactctat tctatctggc
    19981 tacactagta aacggacagc actactagat gatagtttca agccatctga ctacagtatt
    20041 gttaccaaga aatcaaatac agagctcaac gactatcttg ataacttggt tactaaatgg
    20101 agcaaggatg gtagtttgca gaaactttat gaccgttaca agctcaaacc atctagtcat
    20161 accgcagatt aaggaggata ccctatgaca gatttatcat cttggacagc ctattttcag
    20221 gattttggac aatttttcaa tggtttcctc tttactcttg ccctagcgat tggatccttt
    20281 atcctcgcca tggtcttagg aatcttcttt ggtgccatgt caaccagtaa acgtccaatt
    20341 ttacgcattt tagctcgcat cttcgtggaa ttttaccaaa acactcccct cttggtgcag
    20401 tttgttattg ttttttatgg cctacctctt atcagtgacc acatcatcat gattccaatt
    20461 tattggacag ccgttctctg cgtgggactc tatcacggcg cttatatcgc tgaggttatt
    20521 cgttcaggga ttcagtctat tcctagtggt cagatggagg ccgccttgtc gcaaggtttt
    20581 acctatatca gtgccatgcg cttgattatc ttgcctcagg ccttccgcat cattctccct
    20641 ccattgacca accaaattgt taacctcatc aagaacacat ctactgtagc tatcatctct
    20701 ggagtagact tgatgtttgt gactaagtct tggtcggctc tcaacggaaa ctatatccca
    20761 gcctttttag gtgctgctct tctctacttt gccctatgct tccctgttgc ccagtttggt
    20821 cgcaagatgg agcaagccaa taaaaaagcc tattcacttt aggaggttac tatggaatct
    20881 attttagaaa ttttaacccc agataaccta gtctttatct ttaaaggatt tggcttgacc
    20941 ctctatattt ctctgattgc catcatcctc tctactatca tcggtaccgt gcttgccgtc
    21001 atgcgaaatg gaaaaaatcc tatcttacgc attatttcca gtatttatat cgagtttgtg
    21061 cgcaacgttc ccaaccttct ctggattttt actatctttt tggtgttcaa aatgaaatcc
    21121 acaccagcag gtattacagc ctttactctc tttacatcag cagccttggc tgagattatt
    21181 cgaggcggtc tcaatgccgt agacaaggga caatacgaag caggaatgtc acaaggcttc
    21241 acctcagccc aaatcctcta ctacatcatt ctcccacaag ccatccgcaa aatgctacca
    21301 gccatcattt ctcagtttgt taccgtgatt aaggatacca gtctcctcta ctctgttatc
    21361 gccctacaag aactctttgg agccagccaa attctcatgg gccgttattt cgaaccagag
    21421 caggtcttca gtctttacat cctgattgcc ctcatctact tcagctttaa cctagcgatt
    21481 tctagcctgt ctcatatgct agccaaacgt tggcaacaag ctgcagaata atactcttcg
    21541 aaaatctctt caaaccacgt cagcttcacc ttgccgtact caagtacagc ctgcggctag
    21601 cttcctagtt tgctctttga ttttcattga gtataaacag ccactctcca gttcaattgg
    21661 agagtttttt gatgagagta gatatttata gacctcaatt tgacaccata cattttctat
    21721 gataaaatgt aacaaattca tttacaacaa atcgaaatct aaatgaaatg gaattttcta
    21781 tgaaatcagt caaaggacta ctctttatca tagctagttt tatcttgact cttttgactt
    21841 ggatgaacac ttctccccaa ttcatgattc caggactagc tttaacaagc ctatctctga
    21901 cttttatcct agccactcgt ctcccactac tagaaagctg gtttcacggt ttggagaagg
    21961 tctacaccgt ccacaaattc acagcctttc tctccatcat cctactaatc tttcataact
    22021 ttagtatggg cggtttgtgg ggctctcgct tagctgctca gtttggcaat cttgccatct
    22081 atatctttgc cagcatcatc cttgtcgcct atttaggcaa atacatccaa tacgaagctt
    22141 ggcgatggat tcaccgcctg gtttacctag cctatatttt aggactcttt cacatctaca
    22201 tgataatggg caatcgtctc cttacattta atcttctaag ttttcttgtt ggtagctatg
    22261 cccttttagg cttactagct ggtttttata tcatttttct atatcaaaag atttccttcc
    22321 cctatctagg aaaaattacc catctcaaac gcttaaatca cgatactaga gaaattcaaa
    22381 tccatcttag cagacctttc aactatcaat caggacaatt tgcctttcta aagattttcc
    22441 aagaaggctt tgaaagtgct ccgcatccct tttctatctc aggaggtcat ggtcaaactc
    22501 tttactttac tgttaaaaat tcaggcgacc ataccaataa tatctatgat aatcttcaag
    22561 ccggcagcaa agtaacccta gacagagctt acggacacat gatcatagaa gaaggacgag
    22621 aaaatcaggt ttggattgct ggaggtattg ggatcacccc cttcatctct tacatccgtg
    22681 aacatcctat tttagataaa caggttcact tctactataa cttccgtgga gatgaaaatg
    22741 cagtctacct agatttactc cgtaactatg ctcagaaaaa tcctaatttt gaactccatc
    22801 taatcgacag tacgaaagac ggctatctta attttgaaca aaaaaagtgc ccgaacatgc
    22861 aaccgtctat atgtgtggtc ctatttctat gatgaaggca cttgccaaac agattaagaa
    22921 acaaaatcca aaaacagagc ttatttacga aggattcaag ttcaaataag taatcatact
    22981 ctcctgggat ttcccaggag agttttttat agccaaatga aataagacct gaacgatgga
    23041 attttggcat tcaaatcaat tgataagaat attttatagt ggagtgaaat aggatacgaa
    23101 caaattgatt aggaaaatca aatgaattta tagaaatctt ttagcagtta tgttgtccta
    23161 ttctagtttc gaaacgctat agaagcagca ttgtgctagt ctagattcag tttactatac
    23221 taaaacgagt agcttggaat caaaaaaccc accctcacag gcaggtttta tctgtattat
    23281 tcagctagat tatgctttac cttctgaacc gaatacgtcg atacgttctt caaccgatgc
    23341 ttggatagct tttacaccgt cagccaagaa tttacgtggg tcgaagagtt ttttcttgtc
    23401 gtattctgct tcgtttgctt cgtagtcacg agcaaattta cgagttgcgt tagcgaatgc
    23461 gatttggcat tctgtgttaa cgttaacttt ggcaacacca agtttgatag ctgcttggat
    23521 ttgctcatca ggaatacctg atccaccgtg caatacgatt gggaatcctg gaagagcttc
    23581 tgtcaatttt tgcaagtggt caaggtcaag accttcccag tttactgggt aagggccgtg
    23641 gatgttaccg ataccagctg ccaagaagtc gataccagtt tcaaccattg ctttagcgtc
    23701 ttcgattgga gccaattcac ctttaccgat gattccgtct tcttcaccac cgatagtacc
    23761 aacttcagct tctactgaga tacctttagc gtgtgctttt tcaacaactt ctttagccaa
    23821 tttaaggttt tcttcaactg gaaggtgtga accgtcaaac atgattgaag tataaccaac
    23881 ttcgatacac tcaagtgcat cttcgtagtg accgtggtca aggtggatag ctactggtac
    23941 agtgataccc attgattcaa caaggttagc gatcaagttg cgagcaactt tgtaaccacc
    24001 catgtattta gcagcaccca ttgaagtttg gatcaaaact ggagcttttt tagcttctgc
    24061 tgcgcgcaag atagcttgag tccactcaag gttgtttgtg ttaaatccac caactgcata
    24121 accgttgtca cgggctgctt ggacaaattt ttctgctgaa acgattgcca ttttatcagg
    24181 cctcctgtat atttttatgg gtcatcccat ttacattgtt cattttatca ctttttgcca
    24241 aaaaaatcta gtttttcccg cagtttcgat tgattttctt ctaactccat ctatgtaaac
    24301 cctttctctc cctagtcttg gacgactttt ggaaaatcta taaagaaggt taaacgattc
    24361 tcctccatct cgaaacgata agctaatttt tcatgttcta atagactctt aaccacaaag
    24421 agccccatac cagacccctt gaccttgcga ctggcattgt cagaaaaaga ctgggctagt
    24481 ttttcttgtt cctctgagct acagctattt tcgataaaaa gttctccttc tctttctcca
    24541 attcgaacta agccacctgg aacagagtgc ttaatggcat tgctgatgag attagaaaga
    24601 atcaacttca taactgatgg gtttagataa gcctgctgat gggtcaaact attgtctatc
    24661 tggagctctc tttccttggc tagcaaggca taatctttga ccagattttg cgtcatctgg
    24721 aggaggtcaa ttgtttccct atcatctcgc aattcctgca cagaagagag ggaaagtatc
    24781 tgcagaacat ggtgattgag ttcatccaca atccccaagg caactcccag atactggtct
    24841 ctattcttat aacgaccgat attctctctc atattttcga ttaggatttt caaactagcc
    24901 agcggtgttt tcaattcatg agaagctcct cgtaggaatt cgaccttcat cttctccagc
    24961 tggagaatgg cttcattctt ttcatgcaag tccgcaataa cagtcaagag atgctggtag
    25021 aggctattga tttgttcctt gagattgcct atctcatcct tagaatccac gcgcaatcgc
    25081 acttgggaat ccaggtccat catccgacgg gtcacccgct tgatttccaa aatcggtgca
    25141 acaatagtcc gagcgtagat gtaggccacc aagagggaaa tcagaaagga ggccagcaag
    25201 gtatagggaa gaaactggag actgatttgc tccgcttcct tttgtaaatc catggaagct
    25261 agaaactgga gaatcatagt accaccgtct tgcgttttca cctcgcgctc ctcaataaag
    25321 agagaggttg tctggcggtc tgtgtccaga ggaagactgt ccttgacttc taacttgtcc
    25381 tcggtcatct cacctttgac ggtccccttg atatcactag tctgggaata caagtctaac
    25441 acttgctcga tactctgcct atctttccct tctagggact gggcaatggc tgttgccttt
    25501 tgaccaatgg tttcctgacg atgactcaga taagtcgaag gaaaaagaaa ataaatagct
    25561 aaatgaaggc agataaccag aacactaaat atcgagaagg tatagataaa tatctttgta
    25621 aataaacctg ttcgtttcat tttcgctcca atttataacc aacattgcgc acagtgagga
    25681 tacaatccaa gtctagcttt ttccgcaatt ccttgatata aacatcaata acacggtcaa
    25741 agggaacctc atctgtcgct ttccagacgg catcgataat ctgagaccga gtcaaggccc
    25801 ggccttcatt tttcactaga tagtccagaa tttccaactc tttggcattg ataggcactt
    25861 cttgacctgc gaggcttgca ctgtagcttt caaagtccac cttggtatcc ttgtaagaaa
    25921 agattcgtcc tgtatcgtag tagcgcttga aaatcgcgtc caccctcact tttaagaggg
    25981 agagggagaa aggtttttcc agatagccat ctgccaaaga ggcaaaggca ctcatcttgt
    26041 attcctcatc ctgaaaagct gtcaacatca agacaggaac ctgactggtt ttacgaatct
    26101 cagctaggac ttctaagccg ttaagcttgg gcatctggat atccagtaaa accagggcca
    26161 cctcatagct agaaaattgc tccagagctt cctgaccgtc cgctgcctca atagtttcat
    26221 agccacaatc cgtcaaataa tcactgaccc cctcacggat catctcttca tcttctacaa
    26281 ttaaaatttt catactttaa ctgctctcta ttttttattt ttcttagaat aaatacctac
    26341 tctattttct attatagtct cttgctggcc ttttgtctgt aagcaactga ccactagata
    26401 aaacgttgtg aaattccttt ctcataaatt ccataacttt agtatattat atttaagcac
    26461 taaagtacaa agaaagcaac tgaaagcaat gattttcacc actgctttca gatttatttt
    26521 gaattgttaa atagctattc ctatccacta ttcttgaata gaaacacaag atgcaatctt
    26581 tattccagac tcattttttt caaatttatt caccatccag caagagctct tttggttgtt
    26641 ttctaaggag attgcttgaa gcaagcgcca taacgagaac cactagaacc aaggcaagga
    26701 caaaaatgat gataaagtct gatgtctgaa tggaaatgtc taggctcgac aaggtcttgc
    26761 taaagccatc tacttctgca ccgccaccaa ggttagaggc ttgagccgcc ttactagcct
    26821 gtttggcaac acctgaagtc acattggcaa ggacagtgtt tccaattgca tgggcagtgt
    26881 aattagctag gaagtaagca gaaactagag cagggatagc aatcaagata gattcggtga
    26941 tgaattgacc caagatactt gcctgcttga gaccaataga gaggaggatt cccacttcct
    27001 tgcgacgggc attgatccaa agactgagca agagggcaag gagaaggact gagaagctca
    27061 agctacccca gaagaggagg ttggccatct tgtacatacc agagatagat tgctcaagag
    27121 ctgggtagtt agaggagctc ttgacgagtg tgtagctctt ccagttgata ccactgatgc
    27181 cattcaactc tttcataaca tcatccaagt tcttgtctgc tgttacaaag aaggttgcgt
    27241 ccccataaat ggctgtgtct tctgtgtatc cataaagttt tgcagcagtg tgaatgtctg
    27301 taatagctgt gttttcgtaa agttcttgtg agtaggttac tgctgactta ttatgaccat
    27361 caaagagtcc cttgattgtc acttcaactg tttccttggc tcctttttca ttatctgcat
    27421 cgtagatatt agagtccagt ttaaccttgt cccctacttt ccagccgtgt ttggctgcca
    27481 agtccttgtg caagaggatt ttatccttgt cgtcgttggt taagtgctct ccttcgacta
    27541 gtttataaga accagagaca aacttatctt ctttagagga gtcattgaca cctgtaatca
    27601 tcaagctact tccaaaacgt ttggcacgat cagcagtgag attcttcttg gtttctggcg
    27661 tttcaatcag gtcatatcca gtcaaatctc cgatagcgtt gatacgtttg acataagact
    27721 caatggcctt gttttcggtg atttttttga tgtcttcacc cttgatattc ccagcaccac
    27781 gaggcgttcc ttggttgacg cgacgattga tttgcatgga gaagctattg gtgatatttt
    27841 taaaggtctc ctgagaagcc ttggcagtag ctcccttgat tgacaagccg accaaactca
    27901 agctcgccat aaggagaata atcaggaaga tgacaatcga tttgaaaaac ttccttgtaa
    27961 cataggcaaa tgcgttgtgt aacatagatt ccctttctag attttgtttt aatcattcta
    28021 tcaaaataag ctcaaattat ttactagtat tgcgcgtttc agtcagtttc ttatccttta
    28081 attcaagtgt aatatctgac gcttgtgcca cttctttact gtgagttacg acaatcacac
    28141 atttacctgt tttctgggca agtgatttga gtagttcgac aatatctcca gcagttttag
    28201 gatccagatt tcctgttggc tcatcagcta gaataactgg agcttctgag accaaactgc
    28261 gagcaatggc aacacgttgc tgttgaccac ctgataactg gagaacattc cgcttaatct
    28321 ggctttcatc caaaccaagc tcaagaagtg tattcttgct tgcctttttg ttgaccaatt
    28381 ggatattttc cagcggagaa agataatcta tcaagttata attttgaaag accagggaaa
    28441 tatggtgcat gcgatggtaa gaatagccct tcttacgaat atcctctcct tgaaaaagga
    28501 tagaaccttc aacaggacta tctagaccag caagtaggga caagagtgtg gattttcctg
    28561 ctcctgactc cccaataata ctgtaaaatt ttccgggttc aaaattataa ttgatctgat
    28621 ataggactgc ttcagcagta ttcttataac ggtaggtaac atcttgtaat tgtaataaag
    28681 tcatgatttc tccttcttaa ctaatagatg ataaaatttc tttcggtgat tttctaaata
    28741 agaataggaa acaaagggct acagataagc aactaagcag aactagaaaa acataggatt
    28801 ctgcaaaaga taagatgcta gttgataaac tgcttgcttt ggctagtgta tcttgtaagc
    28861 ttacctgatc tccacttgct agtagagttt ggagtaggta agttgtgatt ccgtttcctg
    28921 caacaaatgc tggaagcaaa gctccaagag ataccaaaac tacctctaaa cagaattgta
    28981 ggaagatcga gctcttgcct tttccaagtg caagtaaaat ccccacttca tagacccgtt
    29041 ctctcaacca gagagacaaa accagaatta aggctccagc tcctgctatc aacatcccat
    29101 aaaggaagat ggtcaggaag gtttggaaag ttgcaactga gtctttgatt tgttcaaaag
    29161 ccttgttttc cttttcgact tggtagcctt gattttccaa ggccaagttt tctacctgct
    29221 tcatgagtcc gtccatttcc ttaggatttt ctacatagaa gcgtgctgca ctgacttgag
    29281 cttcactatt gcccaaaagg gtttggctac tttcataatc tgtaaagact tgattttcac
    29341 tgaagtcaga agacaagcct gtgaatttct cttgtttttt accagaaaag atgccgataa
    29401 tctcaaactc tactgtttgt ccttttccag attcagactg accagcatcc aagccaatct
    29461 tgtcatgaag tgaaagaccg ttcttcttag ccaattcttc gtggataagg attttcttgg
    29521 aatccccttt ttgaaggtgt cgcccttctt ttagattgaa agccgaactg gtaaaggtta
    29581 catccttgga tgaatcctca agagccgtta agctaaccaa gttattgtct gcagctgata
    29641 aatcatcacg ctccacgctc tgctcgccag tcactgcttc cttgtctttt agttttgcga
    29701 ccgtctcaag ttcaggagag acattttcca gccccttaat cttgcttaca gatgctaggt
    29761 ctgacaactt gaatgtctga ccattctcta tcttcttaat agaaaaagat gtattgagtg
    29821 atttataaag attgctttct actgttttgt tggacttcat cagagtcaaa caggctgaaa
    29881 ttccggccaa taagaccaat aaaatcagaa ataaaataaa acttctcagt cgctttctgc
    29941 tgacataagc ccaagatctt tggattggat tcatttgtca cctccatatt tgtaagacta
    30001 ttataaaacc caaatatgaa atgtttatga aatacgaaaa aaaatatcga gtaggggata
    30061 atctctagcc cctctcacac caccgtacgt g
//
LOCUS       DAVBNZ010000023        27949 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000023 DAVBNZ010000000
VERSION     DAVBNZ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27949
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.023"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ860_001066"
     CDS             complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ860_001066"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET3119503.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1995..2927)
                     /locus_tag="VQ860_001067"
     CDS             complement(1995..2927)
                     /locus_tag="VQ860_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET3119504.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDVVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSAVCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2924..3781)
                     /locus_tag="VQ860_001068"
     CDS             complement(2924..3781)
                     /locus_tag="VQ860_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3119505.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNSGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3785..5131)
                     /locus_tag="VQ860_001069"
     CDS             complement(3785..5131)
                     /locus_tag="VQ860_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3119506.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5144..5428)
                     /locus_tag="VQ860_001070"
     CDS             complement(5144..5428)
                     /locus_tag="VQ860_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3119507.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5432..7462)
                     /locus_tag="VQ860_001071"
     CDS             complement(5432..7462)
                     /locus_tag="VQ860_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET3119508.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7653..8660
                     /locus_tag="VQ860_001072"
     CDS             7653..8660
                     /locus_tag="VQ860_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3119509.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8663..8863
                     /locus_tag="VQ860_001073"
     CDS             8663..8863
                     /locus_tag="VQ860_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3119510.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ860_001074"
     CDS             9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ860_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET3119511.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ860_001075"
     CDS             9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ860_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3119512.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9784..11664)
                     /locus_tag="VQ860_001076"
     CDS             complement(9784..11664)
                     /locus_tag="VQ860_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3119513.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASMIY
                     TT"
     gene            complement(11658..12527)
                     /locus_tag="VQ860_001077"
     CDS             complement(11658..12527)
                     /locus_tag="VQ860_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3119514.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(12611..15256)
                     /locus_tag="VQ860_001078"
     CDS             complement(12611..15256)
                     /locus_tag="VQ860_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET3119515.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(15347..16627)
                     /locus_tag="VQ860_001079"
     CDS             complement(15347..16627)
                     /locus_tag="VQ860_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET3119516.1"
                     /translation="MIYSKEIVREWIDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            16798..18882
                     /locus_tag="VQ860_001080"
     CDS             16798..18882
                     /locus_tag="VQ860_001080"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET3119517.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QGGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADH
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(18922..20601)
                     /locus_tag="VQ860_001081"
     CDS             complement(18922..20601)
                     /locus_tag="VQ860_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET3119518.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGSLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            21357..22586
                     /gene="arcA"
                     /locus_tag="VQ860_001082"
     CDS             21357..22586
                     /gene="arcA"
                     /locus_tag="VQ860_001082"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET3119519.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            22644..23660
                     /gene="argF"
                     /locus_tag="VQ860_001083"
     CDS             22644..23660
                     /gene="argF"
                     /locus_tag="VQ860_001083"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET3119520.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            23825..24772
                     /gene="arcC"
                     /locus_tag="VQ860_001084"
     CDS             23825..24772
                     /gene="arcC"
                     /locus_tag="VQ860_001084"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET3119521.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            24983..26494
                     /locus_tag="VQ860_001085"
     CDS             24983..26494
                     /locus_tag="VQ860_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET3119522.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            26516..27847
                     /locus_tag="VQ860_001086"
     CDS             26516..27847
                     /locus_tag="VQ860_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET3119523.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQANMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKETGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEICIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         8235 a         6217 c         5365 g         8132 t
ORIGIN      
        1 aaccatacct acggcaaggc gacgttgacg tgatttgaag agattttcga gtatgagttt
       61 attttttacc tgacttgtcc atattccaga agtctgtcac ggctccgcgt gaagcagatg
      121 atacgatgtg ggcatattta ccgaggacac cacggctgta aagtggtggc aaggttgttt
      181 ctgccttgcg tttttcaagt tcttcttcgg atacggccat ggaaatttct ttggtatctt
      241 ggtcaaccgt aacgatatcg ccggtacgga gataggcaat tggtccacca tcctgagctt
      301 caggagcgat atgtccaaca accagaccat aagtaccacc agagaaacgt ccgtccgtca
      361 agagggccac cttatctccc tgacctttac caacaatcat tgaagaaagt gacagcatct
      421 caggcatacc aggaccacct ttaggtccaa caaaacgaac aacgactaca tcgccatcaa
      481 cgatttcatc tgtcagaacg gcctgaatcg catcttcttc tgagtcaaag accttagctg
      541 gcccaacgtg acgacgcact ttaacacctg ataccttggc aactgcaccg tcaggagcaa
      601 ggttcccgtt caagatgata agcggaccat ccgcacgttt tggattttca agtggcatga
      661 taactttttg gcctggagtc aagtctgcaa agtcagccaa gttttcagct acagtcttac
      721 cagtacatgt gatgcgatct ccgtgaagga aaccatttgc caacaagtac ttcataaccg
      781 cagggacacc accgacttcg tagaggtctt ggaagacata ctgaccagat ggtttcaagt
      841 cggccaagtg aggcacacgt tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat
      901 ttgcggcatg ggcaatggcg agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca
      961 tcgttacagt gatagcatct tcaaaggctt cacgagtcaa gatatctgat ggtttgagac
     1021 caagttccaa catcttaaca acagcacgtc ctgctgcttc gatatcttct ttcttatcag
     1081 ctgattcagc tgggtgagag gatgaccctg gcaaactcat ccctagaact tcgatagcag
     1141 ttgccatggt attagcagta tacataccac cacaaccacc agggccaggg caggcattac
     1201 attcaagacg tttcacgtcc tcagctgtca tgtcaccgtg gttccatttt ccgatacctt
     1261 caaagacaga aaccaagtcg atatctttac catcaagatt tcccggtgca atagttccac
     1321 cataggcgaa aatggctggg atatccatgt tggcaatagc aatcatagat ccaggcatgt
     1381 tcttgtcaca gccaccgata gcgacaaagg catcgacgtt gtgaccactc atagccgcct
     1441 cgatggagtc cgcgataatg tcacgagatg ttagagagaa acgcatacca ggcgttccca
     1501 tagcgatccc gtctgctacg gtaatggttc caaactgtac aggccaagcg cctgcagatt
     1561 tgacaccttc tttagccagt ttcccgaaat catgcaagtg aatgttacat ggtgtatttt
     1621 ctgcccaagt cgaaatcact cccacaatcg gtgtttcaaa gtccttatct gtcataccag
     1681 tcgcacgaag catagcacgg ttaggtgatt taaccatgct gtcataaatg ctactgcggt
     1741 gacgtttatc taattcagtc atcttatccc tcccatttca gtttttacta ttatagcaca
     1801 atttaaaggc aatgaacaga ataaaattct tgaattttca gaaaattcta tacgcatgtg
     1861 aaatatttaa aattaaaaac aacaaagcgg attagtgcac tttctgatga ctagaatatg
     1921 ctttttaatc cgctttcttt aaataacgta ctgtaatttt tacagaaatt ctttcaaata
     1981 agtgtattta acatctatct tgcattataa atttctagaa ccttctcttt tatattcgat
     2041 tcactcaaac catactcatt aagaagataa tccattttcc ctacttgacc aaatctttct
     2101 tgaacaccca tccgatgaat ttttgttatt ccatcatcag agaataattc acatacagca
     2161 ctgccaattc cacctatctg attgtggttt tctacagtaa atatagtttt tccacttaac
     2221 attgttttta tctgttctgg tatcggtttg attctaaata aatctatcac acctactgaa
     2281 taacctaatt tagacagttc atctgcaact cgaatacttg gagcaaccat tatgccagaa
     2341 gcaacgatta caacatcttc accatgcctt aactcaatgt agcctttaga aaaatcttct
     2401 ccaccttgat acacaggaac tggagctttt ctaattgttc gaatatattt tagtcctttt
     2461 aagtctaatg tctggttcaa tatttcacga aattggatat catcagttgc ttcaaaaatg
     2521 atcgatttag gaattaaacg taacaatcca atttcttcaa atggcatatg tgtcccacca
     2581 ttcatttctg cagttactcc tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat
     2641 ccaagagaaa taaataattg atcaaatact cttcgtgaag caaaaggacc aaatgtatga
     2701 agataaggtc taaacccctg aatagacaag cctgctgcaa ggccgaccat ttctgcttcc
     2761 ataatcccaa cattcacata acggtctcca aagtcctttt caagattatg agtagccatc
     2821 gaacttgaca aatcggcttc taagactact atatcagaat cactttgatt agcctctaaa
     2881 aggaagtctc tatatacatg ccgtaattct ttcgtacttc tcatcattct gtttcctcca
     2941 attcctgact taatctttct acaactgaag ttaacatttg tttctcctct acagtagggc
     3001 gaagatgatg attggatttc atttcttcca gctcttgaac cccttgacct ttaatagtat
     3061 ctaatacaat gcacttaggt gatgaattat ttgactgttt taattggaca atcccttcat
     3121 aaatttctct aatatctgaa cctttgaccc taatggattc aaatccaaat gctgaaaatt
     3181 tttctacgaa atcacctgaa ttacaaatat cctttgtaaa accatctaat tgttttttgt
     3241 tatcatcaac aaatacaatt aagttggata actgttgatg agaagcaaac tgtatagcct
     3301 cccaacattg tccctcattt aactcaccat ctccaacaat agcgtaagta taaaagggac
     3361 tctttcttat tctctgacca tatgcaagtc cagttgcaac actaattcct tgtcctaaag
     3421 agcccgttgt catatctatg cctggcgtta gatttctatc aggatgagac ggtaatttgg
     3481 ttccatttgt atttaaagaa tataagaatt ctttgtcaaa gaaaccattc aaatagagtg
     3541 tactgtatag agctggtcct ccatgacctt ttgataatat gaaataatct ctatctcgtg
     3601 ctgcaaatat ttctggagtc attggcatta tttcaccata aagcactgct aacacttcta
     3661 cgatagacaa acttcctccg taatgtccga atccaagatg attcaatgtt ctaagagtat
     3721 ttaatcggat gttagtcgca aattttctta acccatcttc tctattttta cttaaaatca
     3781 tcccttattc ctcctttgca gatggctttt taataaagga tactccaaac ataactgcta
     3841 aaataagaac aagaccaatc acaatgcctg cttgtgagcc aaattgattt aacattccta
     3901 aaataattcc tgatagacca aaatctgcat ctgagaaagt tgatccttgg aaaccaagtc
     3961 ctcccaaaac tggcattaaa aagactggaa gaaaactgat taaaatacct tgtaaaaatg
     4021 ctccaatagt ggctccacga acaccaccag atgcattccc aatgacacct gcagtcgctc
     4081 cacagaagaa atgaggcaca acgcctggta agataacaac cgttcctgaa gcaatcataa
     4141 ttgccatact tactaaacca ccaacaaaac tagagataaa tccaattaga actgcattgg
     4201 gtgcataagt ataaacaatc ggacaatcca aagcaggttt tgaattaggt acaagacgct
     4261 ctgaaatacc tttaaaggct ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa
     4321 taacaaatac ccctgctgca aattgacctg ctaattgtaa agcataaact agaccacttg
     4381 taccactact gatttctttt tctatatatt ctgaccctgc aaagatagct acaataatgt
     4441 aaataactgc catggataaa gtgatactaa cagtactatc acgtaaaaaa gctaaactct
     4501 ttggaaattt aatgtcctct gttgattttg atttgtcacc gataaggcta ccagtaaaac
     4561 cactcaacca atatcccaaa gaactgaaat gacctaaagc taccttgtca tttccagtta
     4621 attgaaccat atatttttgc acaaatgctg gggaaatact cataataata ccgagtgcta
     4681 atcctcctag taagataaga ggcaagctag taaagccagc aactgataaa atgaccgcaa
     4741 tcatacatgc catatataga gtgtggtgcc ctgttaaaaa aatatattta aatcgagtaa
     4801 aacgagcgat taagatattg aacaccatgc ctgcaaacat aatcattgca gtagctgagc
     4861 catatgttgt taaagctaca gctacaattg cttcattatt cggcacaacg ccagataaat
     4921 gaaaagcatg ctcaaacatg gtaccaaatg gatttaaaga attttgtaca attcctgcac
     4981 caccagatac aactaagaaa ccaacaaagg tcttaattcc acctttaata atatcaggta
     5041 atttcttctt ctgaagaact aatcctaaaa ttgcaattaa agctactaaa atagctggtg
     5101 tactaacaat atccaatatg aacttcatca tgacgctagc ctcctatata agtccttttt
     5161 cttcacaaag tttagtaatt aattctcgta gttcatccat atcaataata ctatttaaga
     5221 tacgaacatc tccaagatga ctagctgaat cagctagatc acgaccaaca atccaaatat
     5281 cagctgcatt tggatctgct ccacctaaat cataatgttc aacttctaca tccgaaacat
     5341 tcaaatcact caatacagat tcaatattca tctgtaccat aaaacttgaa cctaatcctg
     5401 aaccacaagc tgtaccaatt tttaacatta tctaatcctc ctgtttaatt atcattttaa
     5461 tgtcatcata gttttttgat gatattaaag tttgaacatg atttttatct cttaaaattg
     5521 ttgttaaatg tgacaaagcc tttaaatgac tctcattatc aatggctgca atacaaatca
     5581 acaatcttac ctcttgttct ggattatcca ataaataaat cggttcttcc aaaactaaca
     5641 ttgacattcc tatttcattc acaccttcat ctggccgagc gtgaggaatt gctactccct
     5701 tccctaaatt aataaaaggt ccaaactctt ctactttttg aatcattgcc tcagggtagt
     5761 tctcagttat cttatcttga tccaaaagcg gtttagctgc taaacgaatc gcctccttcc
     5821 atcctaattt ttgcgaacta acctgatagg tttctttggt aataagttgt tctagcactg
     5881 gtacaatttc ctttctatca tttttttgat aaagataatt ctttaacgcc aatcttaatt
     5941 ccaattcttg tgtaataatt ccatatcttt tgacaatatt caggatttgt tcaatctcaa
     6001 aatctccata ctctaaattc ggaaaatctt ttaacactag ttctactagt tgtattgctt
     6061 gctcttcagt catcataacc gaaactagat aatttggctt ttctgtctcc acctttatgg
     6121 tagaaaaaac catatcatag tcactactag ctttcacctg taaatcatca atctttgagg
     6181 ttcctataaa ctcaatttga ggaaataatg ctaatagatt ctcttttaac atcaatgaag
     6241 aactaacacc attaggacaa atgattgctg ctttatagca tttttgaggc aaagtatctg
     6301 ctttctttaa ataacctccg aaatggataa caaaatatgc tgtttcacta tcaggtatgg
     6361 gattgtcaat agcgtccatc aagggcatca aagaatcttt gactaattca aataaatcag
     6421 gataatgttc tttaacatgc aatacatatt catttgaact aggtaggccg aactttaatc
     6481 tatagtaagc cggtataagg tggcggcgaa gattttctct caatccttcc ctttgtttaa
     6541 aatgtaacaa agaaatatct tccattctac ttataatagc ctctgttaat tgattaaagt
     6601 aaaccggagc aacatctact tcaccttcaa agcaacttga taataaaact gtgatatagc
     6661 gataatcatc ctcagaaaac accgtatcta taattcccaa atcaaccact gtatccaata
     6721 aaatagtggt tatatcttga ataacaggag atactaatgt ctctgaaaga catactcttt
     6781 caacatccct ttgataccta cacagaatga atactaaacc gaaaaggcaa acttttaatt
     6841 gattaacaat aggtactagc tgtagcttct cataataatc tttaactacc tgatttatca
     6901 aatcataagt taatgaatac ccccaactgg ataaaacata atccaaaccc caaatcccta
     6961 tggaggattc cagcaactca ctaaccattt gaaaagctaa gcggtgctta ttccactctg
     7021 aaccgtgtaa agtataacct tttgctctac tgtaccctag ctccaaatca ttatctaaca
     7081 taatctttct taatgattga atatcagata aggttgtatt cttacttact ttcaaaaagt
     7141 cttggtaatg attattcgat ataaaatcta atcggcaaaa agtgtaaaga tagattaaag
     7201 ctaagcgagt cgactttggt aaaaccaatt catccgactt aataatatct gtcaaagact
     7261 gcttcgtacg atttgataaa ctatagcgac cttgcttttt atccagcact atccctttat
     7321 tagctagata aggcactaaa taatctattc cttctttgac ttcctttata ggtaagctca
     7381 ccttaacaga taattcatat aatgatagct cacaatgatc catcaaagtc atcaaaataa
     7441 ctagtgctct ataatcaaac atttctcttc ctttctaact acaattatag tgtaaaagtt
     7501 ataagaataa aagagtattt gagcacaata taatctcacc ttttaaaaga aattattggg
     7561 ctgaaagttt ttagtgatta ttttcaactt tctattgact tttaaaaaca aagtgatatc
     7621 atttagatat caaataatgg gaggtcattc ttatgactga aaaactaatc aattcaaaac
     7681 caaatggtgt attcgcattg attctcattg agttgacaat cgtacttggt atctttatat
     7741 ttataatggg tgttggttcg gaaaacattt ttggaattat tatcggacct ttactaatcg
     7801 taattgcagg tctagctcat gctggtttaa aagttgtcaa acctcaggaa gctctggttc
     7861 tgacactctt tggtaattat acaggtacca tcaaagaacc tggtttttac tttgtcaatc
     7921 ccttcagcgt agcagtcaac cctgcaaacc acactcgact tggacaaagt ggtgatgtta
     7981 gcacaaaatc tcctttttta ggagctaaat catcaaatga caatgatgta aatcttgaaa
     8041 ttggcaagaa acacatttcc ctcaaagtca tgaccttgag caattctcgt caaaaaatca
     8101 atgattgctt aggaaaccct gtagaaatcg gtatcgcggt aacttggaga gttgtcgata
     8161 ccgctaaggc agtcttcaac gttgataact acaaagaata tctttcattg caatgtgata
     8221 gcgccctccg taatattgtc cgcatctatc cttacgatgt gtctcctaat gtggatacta
     8281 cgggtgacgg gcaagcagat gaaggtagtc tccgtggctc tagcgaaatt gttgctaacc
     8341 gtattcgtga ggaaattcaa agtcgcgtag aagatgctgg cttggaaatc cttgaagcac
     8401 gtatcactta cctagcttat gctccagaaa ttgctgccgt tatgcttcaa cgccaacaag
     8461 catctgccat tattgatgca cggaagatga ttgtagatgg tgctgtagga atggttgaaa
     8521 tggcactaga acggctcaat gaaggggaat tggtagaact tgacgaagaa cgaaaagctg
     8581 ccatggtttc aaatctcctt gtcgttcttt gtggcaatca tgatgcacaa ccaattgtca
     8641 acacaggaag tctttactaa agatggctga agctaaaaaa aagcagatcc cccttcgact
     8701 ctcaacaaag ttatacgctg cactcgcatc atgggcagaa gacgactttc gttcagtcaa
     8761 tgggcaaatc gaatatctcc tcacagagtg tgtcaagcaa cggaaaaaag acggaaaata
     8821 cgtatcagaa accattgacg aaccatttga gattgatatt taacaccttc tcctgtctgc
     8881 cgtgtcggat aggagaattt tttcatcttt ttttgtcaag taactttact ttacaaaaaa
     8941 aatgtgttat cctagtatgg ttgatgaaaa tcagtagatt gaatcgaata taaataccta
     9001 aaggagaaat caaaatggca gtacctgcac gtcgcacttc aaaagcgaag aaaaacaaac
     9061 gtcgtacaca ctacaaagta acagctccat ctgtaaactt tgacgaaact actggagatt
     9121 actcacgttc tcaccgtgta tcacttaaag gatactacaa aggacgtaaa atcgctaaag
     9181 ctgcatcagc tgaataatag aagggagata ccatgcgcgt aaatattaca cttgaacaca
     9241 aagaatctgg tgaacgcttg taccttactt ctaaaaacaa acgtaacact ccagaccgcc
     9301 ttcaattgaa gaaatactca ccaaaacttc gcaaacacgt tgtgtttaca gaagtgaagt
     9361 aagcattcaa tacgaatcaa tacagaagaa aaacgcttga tcagcgtttt ttctttttgt
     9421 taatttcact atattgcaag ggaaatcatt cgaatgacta cattattgat aatatttgtt
     9481 aagccatcaa aagtaattaa catttcatag cgagtaatcc tatttaaact cgtcccacta
     9541 tctatttctt cttatctctg tgttataatc ccgactttat cataagtttg tctaactgta
     9601 gcatttgaaa ccagataatt cttctgtttc acgcgaaaca ccctgcgcca agcaaggtgt
     9661 tcttgttttt atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
     9721 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
     9781 gtattaagtc gtataaatca tcgaagctgt cgcaatggta tgccactggt tagctgtagt
     9841 tgctgcgaaa tccttgtctg cgtagaagtc agtaaatggt aggatttcaa cttccagctc
     9901 gtcgatgcgg tcaagctggc cagccagata aacctcgata cggctttctg ctcgtttgat
     9961 gcgttgcaag agtccgccca tacggatgtc aactgtatcc aaaccaaaga ccttgttttc
    10021 tttcagccat tggtgactaa agagggcatg gaagtcttca atttggcttc taagttctgg
    10081 taattcttgt ctggcgattt gttgtaaact ttctttatca tccgcttggt aggcctgacg
    10141 aatgcgtcgt cccacatcta ctttgctact taaaatagca ttcaactggg cctgagtttc
    10201 aaagagataa gcatagtttc cagctttttc tttaatgtta gcaagcgtct cagcagcctg
    10261 agcgaagtgt ggcttgtcct gttcaggtgt catgtgtcgg tcaagtatcg gacagagaac
    10321 atcctgataa aagacatagc ggttgggatt gatgccactg agattacctg gtaggtctgg
    10381 taagaggttg gcaagatcaa tctgcataaa atcctcaacc gttagaccag tattggtctt
    10441 gaaatgcgca gacaaactat ctaggtcatt gcgatagctg agttctgccc agatttgcaa
    10501 gcttggtagg atagagaact gggcagtttc accaccattg tctccccaac ccgttacgat
    10561 gacttcttta atctgattgg cacggcaggc tttattagcc tcgatagcca ctagacggct
    10621 aaaatggttg tgaggtgtaa agccaatcca cttccaagct ccccctgcaa atgcaaggtc
    10681 atggctaatc ttgtgatgat tgcggaaatt acggttgtat ttttcctcgc tatcctgata
    10741 ataatcccag taaaccagag tcacacggtc tttgagacgg tctaggtaga cacgagtttc
    10801 ctctggaatt tccacatcac ggtcgtactg gccatccgct gacatgagtt tgaagaacat
    10861 atcactccac atctggcagt ggaaaccata tttgtcagca atatccagca cgcgctccaa
    10921 gtgttggcac atgaggagac tacgatccac aacaccgttc aaaatcaggt agcgtcccaa
    10981 accaaccaag tgggcttcgt ccatcccgat attgaccttg cgagtcttca gtttagacaa
    11041 cgtggcaaac atgccatcaa tcaggtcata aaccttttct tcgccaatga gaagaatgtc
    11101 ctctacatca cggagctcct gcacttcctt gacaccccat ttgacaaagg ccgacaagtg
    11161 ggccaaggtc tggatgcatg gtacaaaggt catgtcaaac tgttgggcat aggcttcgat
    11221 ttcctgcaac tcctctgctg aataagctcc acggaaatag ccaaagtaag gctgcccttc
    11281 aatctggtaa gtgtcttcca tgtaaagctc aaaggttgag tagcccatga gagccaagac
    11341 ctcaatcatc tgcttggcag aagccacatt cagcaccgca tttcgagaac agtcaaccat
    11401 gtaagccaaa tcttcgtaag ctgcttgttc ctcaatctct actttatcag cttctgctag
    11461 aactgttacc aacaaggata aggcacgata aagttggtga ggtttgcggt aggtcaattg
    11521 atagtgacct tcctcaccct cgatagagat agaggcttgg tcagactgag tgacagccac
    11581 ttccacatct ggtagagaaa tgtgaccttt taaaacctca atagcttgcg tttgtttggg
    11641 actaagtcct gtaaatctta ccattgcttt tcctcctgta gccagttgac aagagcaccg
    11701 tagagattgg catctgcgtg ataggtgcag gcctggataa ctggtgcgac cgtgtattct
    11761 tcgtaggtat cgacaaagtt atcaacagcc ttcttgacat cttggataaa atctggattt
    11821 tgactgatag agccacccag actgatgaca tctggatcga tgagatactg gatattgagc
    11881 aagccttgcg ccagattgcg gttcatgcgc tcaatggctt cttgacaaag agcattacca
    11941 gctgcggcct cttggtaaat cttgcgaccg tcccaatcag tatgaccaga tttttcaatc
    12001 acgtatcgta ccatattccc agttgatgct agttgcgacc agttattaag tttttcagca
    12061 ggggcaaggg ttgtcatgta gccaaattct ccacccagac cgtggcgacc tcgatgaagt
    12121 ctaccattga taatcatggc tccgccaatc cctgtcccaa tcacgacaca ggctgcattt
    12181 tcaagctctg gatgagctag tagttcactg agtccaacgc agttggcatc attttctaaa
    12241 tggacaggta gctgataaga gctaagcgcc tcataccaag aaaagccatg gatgtagggc
    12301 accgcactga agccatcaat cacacctgtc tcttgattga ccgcacctgg aacgctcata
    12361 gcaatcccac tgtaatcctg ttctgacaag cgttgatcta gccacgctag taaatcctcc
    12421 aagttttcag gcgttgaaat acttgtctta tacagtattt tcccatcagg agtcagactg
    12481 gcaaacttaa tcccagtccc tccgatatca atcgttgcaa tggtcattgt ttttaccata
    12541 aaaaggggcg aatcagcagt tagttcttac tttttcgccc ctcctttctt ttgatgttta
    12601 ctttttgaaa ttaaatttct tcttttttga tgaattctgt acgaatctct tgtggatcca
    12661 atggtcctga atgaactgga tatggtcgct caagtaagtc aagaatggtt tgttgatgtt
    12721 ctgatatgcg cacattttct tgactcatat tatagtaacg gaagacatag ccttcttcat
    12781 tttccgccac tttaaaggct gttggacaaa cttgcggtat gctgagaaca gaatggctca
    12841 agaggctacc agtcgcaacc acgcttcctt cctgtctagc aagctgaagg ctggtaaacg
    12901 gtgtctgcaa ggctttggca cgacggaaag ctgaaaagcg ttcttgggct tggtggcatt
    12961 caagtgcaaa ctcgacttca aactcacgca agcattgtgc ttctggcgtt gggaagtagc
    13021 cccagtcacc tagctcacct gatgcacgca aaatggtcac ggcaatggtg ttatccccaa
    13081 ggatttcgta ttcattcaat cccttattgg atacagtcac ccctttttca tcgtcataca
    13141 gactgacaaa agcttgttgg tgttgaggat tttcaggatt ttcccatgaa gcagctggtt
    13201 tgtttggtcg tgtcaccacc tcatagatac tttcagaatc attgcttgga cgcgtgttat
    13261 gagtcttgac caagagacgg atacggtgat ccttggcagt gttagtaaag cgagtcttga
    13321 agcggatttg tggattgtca acgaagacag tcaactcagt ttccagagga atgtttgtca
    13381 attcttctga ccgtccagcc tcacgcttca taaactcgat gataccttgt tgctcttctt
    13441 ctagcttttc atccgcactg acaggcacgg tcaattcatg tttgagcaag attttagcat
    13501 agcgatctgt gttttccaag acctcgtggc ccttaagctc tgcaaagatt ggctctgttc
    13561 cttttggttg gaaatagata tactcgtttc cgatgtcccc acggtcttcg aagcggataa
    13621 agtcttcata ggcttcgtga gttgtcttgt catatactgt gatgttgtca tccacactca
    13681 ccgttacgaa tggtgtatca atcactccgt tttggtaaat accctcacgg tgttcttgtt
    13741 ttccttccag caattggaag gttgtccaag aaagcggcgc taggtgaact ggaatggtca
    13801 cgcgcacttg tcgagcaata cgagcttggc ggaacttgtc ttttggtaaa tcgtactcaa
    13861 aattagctcc gaggtcttcg attgtagcct ctacaggatg accatccaag tcctccacac
    13921 ggtaacttgg caagataaga gcagccatct ttttgtagcc ttctgttggg tgcaattcct
    13981 tgaaatcaca agtcgccaca tcaatcactg tgctgacagt atcgacctta tcatgcaagc
    14041 ctgtgttaat gacagtaaag agatagtcac tttgagcctt atccgtagca attttaccct
    14101 tccactcgtt gagcaaatta cttttaacaa agtttcctac ttggttgacc ttggcaaaac
    14161 gcgtttccat ctcgcggtga acttcgtcca cgctacagcc acagatacta tcatgtggcg
    14221 cattctgcaa aagtgttttc caagcatagg tcaactggtc cttgtggttg tgtccaccag
    14281 tgataatagt caagggttct accacttgct ctaggaggtt gctattttct tggaaggctt
    14341 gttttaggta aatgcgggat gaagaagtgt tggcaagtgt gtaccagcca tctgtttcct
    14401 gactggtcaa ctcgcctgta acagttgata agtgttcagg aagcgcacct tctacagctt
    14461 gaacatattc atcaaaagaa ctatgaacaa agattacatc tgggaagagt tcatttgcca
    14521 cacgaatggc ttcgctcaga tttttctgta caggctggtg gtcacagccg ttcatcatca
    14581 accattggtt ggtcgaagcg taggcacgca catctgacaa tttttgtttc cagaaggtca
    14641 aggcctcatc tttgtcaact gggatttcat tcccattact gtaccagtta gcaaagagaa
    14701 tacctaaaac acgactacca tccacaccct gccagtacat ttctgaaaac tgggatgtaa
    14761 actgctcatc ttcaaggact tggttgtcaa atccaatcgg cttcacacca cgaccaaagg
    14821 ccgccacgtg aatgcctgat ttttgaagaa tttgaggcgc ttgtcccata tttccaaagg
    14881 tatctggaaa gtagccaatc tgggttgatt taccccattt ggcagcttct tgttgaccaa
    14941 tcaaggtatt gcggacattg gcttcactgg agatcaagta gtcatcctgc aagatgtaaa
    15001 agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg gaccttgtcg cgattttcag
    15061 ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc atccaagtgg aaactcttga
    15121 actcagggtc attttcaaag agatcaaaga gattgtcaaa caattccacc aactgcatac
    15181 gatggctttc aaaaggcaag taccactcac ggtcccagtg actatgtgag ataatatgta
    15241 caacaacatt ttccatgaag taaaacctca ttctaaattt aaattttaac gttttaaatg
    15301 taaacttgtg attctgataa gaatcggttg agctaaagcg agccccttag cgaatatcca
    15361 agtaatccaa gaccaactca cagaacatca tgttagccca ggagaaccat tcacgagagt
    15421 agagggtcgg atcatctaca tgaaagcttt cgtgcatgac acctgtacca ccatcgcagg
    15481 caaccagctg atccagcaag aattttttct ctgccttatc tcttgttgtc aatccttgga
    15541 tagaaagggc gattggccag atatagcgat agaaggtatg agaacttccg agaccgctag
    15601 cgtattctcc ttggtagaaa tatggatttt cagagctcaa aatggtacga cgagtagctt
    15661 gatacacttc atcatcgacc gaacagtagc ccagataggg cgcagctagt agacttggta
    15721 catttggatc atccatgatg ctggcatttc ctaggccatc cacttcaaaa gcgtaaatct
    15781 tttcgccctt gctgttggtg gtgtaagcgt agtttttgat tccttcttgg atttcatcct
    15841 gaagacgctt ggcatcagca ataacactct ggctatcagc taggtttaat gctgcgaaga
    15901 tttcttgcac ataacccaag actactacag caaacatatt tgacggaatc aagtaactat
    15961 actgacagca gtcatcgctc ggacgaaagg ctgaccaagt catacctgtc actgcaaagt
    16021 caggtccaaa gccatcattt accaaggtgt cttccttacg gtccgtgtct cggacaaaac
    16081 gataaggaga gttcttgtgg tcttgttcca ccgtccacag atggagaatt tccttagtcg
    16141 ctgcgacaaa aatctcatca aactgactag tctcgccagt ctctttccag aggagataag
    16201 ccaactgcaa aggatagcaa agcgaatcca cctcatactt gcgctcccag atccagccgt
    16261 taaggtctgt gtggtcagtc tcgtggtgcc ctttccagtt ctcctcaatg ttgaaggagt
    16321 tagcataggg atccttgagt accaaggtca tctgacgttt gaccaaacct gcaatggtct
    16381 gacgcaggag ggcatctctt ttagctacat gaaggtaggg tctgagttgg gctgtcgaat
    16441 ctcgaagcca catggcagga atatccccag tcaagacaaa agttgaacca tcttctaaga
    16501 tttcaaccgt attgtccaag gtatcggtgt agcaacgctc gaaaacatcc acccactctg
    16561 gatggtcctt agcccgctct gctacttcat ctatccattc tctaacaatt tctttcgaat
    16621 aaatcatcgt gcaattccct ctttcaaaca agtttcatgt tcagtatata gcttttgaga
    16681 cagaaaatac atacacaaat gatagtcatt tttctacaaa atagttattt ttgaaactcc
    16741 ttttctaaag gccctctttt tctgatataa tgtagaaaaa cagctaaagg aaagactatg
    16801 aaaccactac ttgaaaccat cgatacccgc tttggtactg ctagcaagca tgccttctct
    16861 cggggaaata ccctgccata cacaggcgtg ccttttggga tgaattactt tgtgccccag
    16921 accagtgacc agggtggatc ttggtttttt gatccgcatc tgcctatctt tcaggggatt
    16981 cgattaactc accagcccag tccttggatt ggggactact cttggctcct tctgacacct
    17041 gtcaccagtc aactgggggg agacagcctc tttcaccgcc agtcttctta tgatatagat
    17101 aaagcttgct tccagcctca ctatttgaag ctcttttctc tgcgttatca gattgaaacc
    17161 cagctcacac cgacttgcta tggtgcttct attcgtttga atcaaaagca aggcaaagcc
    17221 ctctccctct atcttcacgc agcagatgaa ctgacagtag agcaagtaga taagcggact
    17281 cttgccctgc gacaagaagg taaaactgaa actaacaaaa attcgctaac gatgttcact
    17341 gccctgcaaa tgaacacgga tattcttgct atcagccaag aagctggaga ctggcgaatt
    17401 gacttagcaa gtagtcaaac cgagatgcaa ctagccactt ctttcatctc tccttctcaa
    17461 gctctaatca atctacctca agaagatttt gatagctgta aaacaagtgc ccaagcggat
    17521 tgggaaaatc tcctccatcg ttttgacatt atagagacag gagaggctga ccgaaccttc
    17581 tttgaccact gtctctacag actcttcctc ttcccacaga ctttttatga ggttgatgag
    17641 tcagggaaag ccatccacat ggatctggct actggtactg tcaagcctgg tgtcctcttt
    17701 agcaacaatg gtttctggga taccttccgc accaccttcc ccctctttgc ccttatcata
    17761 ccggagcact atcaacgctt tttagaaggt ttcctcaata gctaccgcga tactggtttc
    17821 cttccaaaat ggctggctcc agatgaacgg ggtatgatgc caggtacact gctagatggc
    17881 attatcgcag atagcgcctg taaggacatg gcccccgacc tagaaggaga actcttccaa
    17941 gccatgctcg aaacagccag caaagccgac catctcggca tcaatggccg ccacggacta
    18001 gcccaatacc aagaactagg ttacctctct accgaccacc atgaaagtgt tagccatact
    18061 ctagactatg cctatagtga cttttgtatc gccagctgtg ccaaaaaact agagaacata
    18121 gaaatcgctg aaacctacaa ggctgcttca caaaattacc gccagctatt tgacgctgag
    18181 acaggttaca tgcgagcacg agacaatcaa ggaaactttc accctgactt ctctccttat
    18241 agttgggggc gagactacgc tgaatgctct gccattcaag ctactttagg cgttctccac
    18301 gacatccctg gcttaatcca actgatgggt ggaaaagaaa cctttagcaa ctatcttttg
    18361 aaagcctgtc aagatgctcc cctctttgaa acaacaggct atggttatga aattcacgaa
    18421 atgagcgaga tggctactgc tccttttgga caaatagcca tttccaacca gcctagtttc
    18481 cacatccctt atctcttccg ctacagcgat taccctgact acactgccct tcttatcaag
    18541 acgctccgtc agaaagcttt tcacccaagt tgggaagcct atcctggaga tgaagacaat
    18601 ggtagtctct ctgcttggta catctggtca gctctcggat tttatccaac ctgtccagga
    18661 aaaccaagct atgacctcgg aatccctctc tttgaccatc tacgagtcta cctagctaaa
    18721 gaagataaat ggctggatat ccatactaaa caaaaccaca accattttaa ctttgtcaaa
    18781 gaatgccgac tgaacaaaac actcgtatca actattcaac accaagacct cttaaaagct
    18841 gaacaactaa ctttcaccct cagctggcta ccaagtcact aataaccaaa agaacctttg
    18901 catcgcgcaa aggttcttct tttatgaaac ttggacttga agttgatcca caagctgacc
    18961 atccaccgtt aggttcagat agaaatccaa ggttttatct cctgcgaaat acagggttgg
    19021 tagatgcaaa tcttttttgc tttcccctgc ttggaattga aggacataaa tctcgtcctg
    19081 ataggcgaca ccatggacac ctgtccccgg ttgaatcgaa atcttagctt ctaaaggacc
    19141 actacattct ctgcgcttaa ctgtaaaata ggcattttct ccctttgcca cagctaggct
    19201 tttttctgca aatgctagtt cctgaacaac ttcttttttt gataatccag gagttttata
    19261 aagggaaatc ttggtcaata caggaataga ttgtgcctcg gtaatcatca cgcgcacctt
    19321 ttgtgcctct actagcgaac ctcgcaagag gcgcttatga ccaactgtga agcccctgcc
    19381 aaattcctgc cagacaccat ccacctctac ttgcacatgg aaagcagaaa tacgttggcc
    19441 taacttcaaa tcttctctca actcaattac atcaaaagtt ttaggagaac ctaagtcgag
    19501 ttctaactgg atgggcaagt ctgcatcgtt tgcccaagag ctggtctcaa ggccgtctgt
    19561 caaatggcga caagcaaagt ctgcggaaag agctggacca gatacctcag ctcccagagc
    19621 caaatcttct ttatagagct cattgcgata ggtcgcaaat tcataaagtc gttcaatatc
    19681 ctttgcatca aagagcccag cttgattcgg cggaatatta agcaagagtg gagttcctcg
    19741 ccctactgag tgaaagtaga tttcgaccaa ctcctcgaga gacttaggat cctgatcctc
    19801 atggtagaac cagcctggac ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc
    19861 cgagggatcc ccgtgctgaa gatagttcag ctctgcttct gttcctagtt tatcaggatt
    19921 caccttttgc cacagtggat cacctgcata ccctcgttca ttgccaatcc agcggatact
    19981 ggtgccttct gttgaaaaaa tcaagcaatc gccctgcagg tcacgaatgg tttcaaacca
    20041 tttttcaaat tcataattaa ccttttgcgc gccctctcct ctggcaccat ccatccaaac
    20101 ctcagcgaac ttaccagcat tcccatagtt aggatttgat aagatttcct tcaactgagc
    20161 cagataatag gcattgtagt ccgcttctcg gtccacatga tagaggggac tatgggcatc
    20221 ccacggtgac aggtagaccc ccatatccat atcaaactct gtggcagctt gggatacttc
    20281 aaggagcaag tcgccctttc ctctcctcca aggactgacc ttaaccgaat aatctgtgtg
    20341 agctgtcgga taaaggacaa agccatcgtg gtgcttgacc accaaaatca actttttgaa
    20401 gcccgtttcc ttgagcacac gaacccactc acgcgcatcc aactgactcg ggttaaagcg
    20461 ctcaggatcc tcctgtccag tcccccattc ttggtcataa aaggtattag gaccgaagtg
    20521 gataaaagct gctagttcat ctcccagata agctagctga gtctgacttg gtaacggtcc
    20581 atgcggtttg attttcttca tcgttatata tctccttctt tagcaacttc tcttgttcac
    20641 aaggttatcc acaggttgtg gataataaac catgatctaa cagccagctc tttccaactc
    20701 caactggtag gctcaggatt ttgctcctca atattccctc ttcaaacagc tctgtcatat
    20761 ggttctgcta acacctctca gaatgctact ctccataatt attctcaggc ttctttcagg
    20821 tcattgtgtg aagaccattc actctccaga cttttccaca gattgtgaat aagtgattat
    20881 tctaaactat cacctcgtcg actataacaa aaaataaaaa gagggtcaat aagataatta
    20941 tctcttccta aatactcaga aaagattcta taatttgtac aattgaacaa gaaatgcttc
    21001 tccaaaatct atcttcaaaa gaatgttgca tctttttatc ctttcacaca aacatttctc
    21061 tttatacaga tccaagtgat aaccagatga taattggaca ctttttggtt atttgtgtat
    21121 tttttgaaaa attttttaaa aaaattttat atcctcttta atagaagttt atgaatttgt
    21181 atatatgtat tccatcctat gttatgtata ataacataaa attgtgctaa atatcataat
    21241 ttatattatt ttccgagaaa ttatagccat tgacattacc taggaattgc gttataacat
    21301 acatgtaagc ggtacccaaa atggtgccaa gtcaaaattt ttaaggagga aaatacatgt
    21361 cttcacatcc aattcaggtc ttctcagaaa ttgggaaact gaaaaaagtt atgttgcacc
    21421 gtccaggcaa ggagttagaa aacttgttgc cggactatct tgaaaggctt ctttttgatg
    21481 atattccttt cttggaagat gctcaaaaag aacatgatgc atttgcccaa gctcttcgcg
    21541 atgaaggaat tgaggttctc tacctagaac aactcgctgc tgaatcattg acctctccag
    21601 aaatccgcga tcaatttatc gaggaatact tagacgaagc caacatccgt gatcgtcaaa
    21661 ctaaggttgc tattcgtgaa ttgcttcacg gcatcaagga caaccaagaa ttggttgaaa
    21721 aaacaatggc tgggattcaa aaagttgaat tgccagaaat tcctgacgaa gctaaagatc
    21781 taactgactt agttgaatca gagtatccat ttgcaattga cccgatgcca aacctctatt
    21841 tcactcgcga cccatttgca acaattggaa acgccgtatc gcttaaccac atgtttgcag
    21901 acactcgtaa ccgtgaaaca ctctacggta agtatatctt caaataccac ccaatctatg
    21961 gcggaaaagt ggatttggtc tacaaccgtg aagaagatac gcgtatcgaa ggtggagacg
    22021 agctagttct ttctaaagac gtccttgcag taggtatctc tcaacgtaca gacgcagctt
    22081 ctatcgaaaa acttttggtc aacatcttca agaaaaatgt tggcttcaag aaagttttgg
    22141 cctttgaatt tgctaacaac cgtaaattca tgcacttgga tactgtcttc actatggtag
    22201 actatgacaa gttcactatt cacccagaaa tcgaaggcga ccttcacgtt tactcagtta
    22261 cttacgaaaa cgaaaaactt aaaattgttg aagagaaagg tgacttagct gaacttcttg
    22321 ctcaaaacct tggtgtagaa aaagttcatt tgattcgttg cggtggtggc aatatcgtag
    22381 cagctgcgcg tgaacaatgg aacgacggtt ctaacacttt gaccatcgca cctggtgtgg
    22441 tagttgttta tgaccgcaat accgtgacca ataagatttt ggaagaatac gggcttcgct
    22501 tgattaagat tcgcggaagt gaattggttc ggggccgtgg tggacctcgt tgtatgtcta
    22561 tgccatttga acgtgaagaa gtgtaatcgc tgttcggtat tcgtcaatag aaaatgtaaa
    22621 aaatagaaag aggaaataat aaaatgacaa attcagtatt ccaaggacgc agcttcttag
    22681 cagaaaaaga ctttacccgt gcagagttag aataccttat tggtctttca gctcacttga
    22741 aagatttgaa aaaacgcaat attcaacacc actaccttgc tggcaagaat atcgctctcc
    22801 tatttgaaaa aacatctact cgtactcgtg cagcctttac aactgcggct atcgaccttg
    22861 gtgctcaccc agaatacctc ggagcaaatg atattcagtt gggtaaaaaa gaatctactg
    22921 aagatactgc taaagtattg ggacgtatgt ttgacgggat tgaattccgc ggattcagcc
    22981 aacgtatggt tgaagaattg gcagaattct caggcgttcc agtatggaac ggtctaactg
    23041 acgaatggca cccaactcaa atgctcgctg actacttgac tgttcaagaa aacttcggtc
    23101 gcttggaagg cttgacattg gtatactgtg gtgatggacg taacaacgtt gccaacagct
    23161 tgctcgtaac aggtgctatc cttggtgtca atgttcacat cttctcacca aaagaactct
    23221 tcccagaaaa agaaatcgtt gaattggcag aaggatttgc taaagaaagt ggcgcacatg
    23281 ttctcatcac tgaagatgct gatgaagcag ttaaagatgc agacgttctt tacacagacg
    23341 tttgggtatc aatgggtgaa gaagacaaat tcgcagaacg tgtagctctt cttaaacctt
    23401 accaagtcaa tatggactta gttaaaaaag caggcaatga aaacttgatc ttcctacact
    23461 gcttgccagc attccacgat actcacactg tttatggtaa agacgttgct gaaaaatttg
    23521 gtgtagaaga aatggaagta acagacgaag tcttccgcag caagtacgct cgccacttcg
    23581 atcaagcaga aaaccgtatg cacactatca aagctgttat ggctgctaca cttggtaacc
    23641 tttatattcc taaagtataa ttttagataa taaaccgtct accaacagct atgagggctg
    23701 cgactaatag ctttagtccg gtcctctttt atataatggt aatctattat ttcttataaa
    23761 atatgtgaaa aatcattaaa ttgaaatcta aacgcattct attgagtgtg ataaaggaga
    23821 atttatggca aatcgtaaaa ttgtagtagc tttgggagga aatgcgattc tttcttctga
    23881 cccatcagca aaggctcaac aagaagcttt agttgaaaca gctaagcatc ttgtaaaatt
    23941 gattaaaaat ggagatgatt tgattatcac tcacggtaat ggacctcaag ttgggaatct
    24001 cttgctccaa catttggcat cagactctga aaagaaccct gccttcccac tcgactcact
    24061 tgtcgctatg acagaaggta gcatcggttt ctggttgaaa aatgctttgc aaaatgctct
    24121 cttggatgaa ggcatcgaaa aaaatgttgc ctctgttgta acgcaagttg tcgtagataa
    24181 aaatgatcca gcttttgtta acttgagtaa accaatcggt cctttctatt cagaagaaga
    24241 agcaaaagca gaagccgaaa agagcggagc gactttcaag gaagatgctg gccgtggctg
    24301 gcgtaaggtc gttgcctcac caaaacctgt tgacatcaaa gaaattgaaa ccatccgtac
    24361 tcttttaaat agtggtcaag tcgtcgtagc tgcaggtggt ggcggtattc ccgtcgtcaa
    24421 agaaaacaat ggacatttga ctggtgtcga agcggttatt gataaagact tcgcttccca
    24481 acgtttggca gaattggttg atgcagacct cttcatcgtt ttgacaggtg tagattatgt
    24541 atttgttaac tacaacaagc caaaccagga aaaattggaa catgtgaatg ttgcccagct
    24601 ggaagaatat atcaaacaag atcagtttgc accaggtagc atgcttccaa aagtagaagc
    24661 agctatcgct tttgtcaatg gtcgtccaga aggaaaagca gttattactt cccttgaaaa
    24721 tctaggcgcc ttgattgaat ctgaaagtgg aacaattatt gaaaaaggat aagttgtttt
    24781 actaataaga tgtattctat ttctagtatc tttatatcaa attagaaatt attcttgaaa
    24841 acatgtacaa tatttcaaaa gatattagtt ttttagactt taatatggta aaacaaatat
    24901 aaatagaaag cgttttctta aatgtttatt taagaaagta gttggttttt tacactttgt
    24961 tagacatcag gaggaaaaac aaatgagtga aaaagctaaa aaagggttta agatgccttc
    25021 atcttacacc gtattattga taatcattgc tattatggca gtactaactt ggtttatccc
    25081 tgcgggggcc tttatagaag gtatttacga gactcagcct caaaatccac aagggatttg
    25141 ggatgtcctc atggcaccga ttcgggctat gctaggtact catccagagg aaggttcgct
    25201 cattaaagaa acgagcgcag cgattgatgt agccttcttc atccttatgg ttggtggttt
    25261 ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg attgcctcta tcgtgaagaa
    25321 gtataagggc cgcgaaaaaa tgttaatttt ggtactaatg cctttgtttg ccctcggtgg
    25381 tacaacttat ggtatgggtg aagaaacaat ggccttctat ccactccttg tgccagttat
    25441 gatggccgtt ggttttgata gcctgactgg tgttgcaatt attttgctcg gttctcaaat
    25501 cggctgtttg gcatctactc tgaatccatt tgcgacaggt attgcttcag cgactgcggg
    25561 agttggtaca ggggacggta tcgtacttcg tctgatcttc tgggttacct tgactgctct
    25621 tagtacttgg tttgtttacc gttatgcgga taagattcaa aaagatccga ctaagtcact
    25681 ggtttatagt actcgcaaag aagatttgaa acactttaac gtagaagaat cttcatctgt
    25741 agaatctaca cttagcagca aacaaaaatc agttctcttc ttatttgtgt tgacattcat
    25801 cttgatggta ttgagcttca ttccatggac agaccttggc gttaccattt ttgatgactt
    25861 taatgcttgg ttgactggtc ttccagttat tggtaatatt gtcggttcat ctacttctgc
    25921 actaggtact tggtacttcc cagaaggcgc catgctcttt gcctttatgg gtatcctgat
    25981 tggtgttatt tatggtctta aagaagataa gattatctct tccttcatga atggtgctgc
    26041 tgacttgctc agtgttgcct tgatcgtagc gattgctcgt ggtattcaag ttatcatgaa
    26101 cgacggtatg attaccgata caatcctcaa ctggggtaaa gaaggcttga gcggtctatc
    26161 ttcacaagtc tttatcgttg taacttatat cttctatcta cctatgtcat tcttgatccc
    26221 atcttcatct ggtcttgcca gcgcaactat gggtatcatg gctccacttg gagaatttgt
    26281 aaatgtccgt cctagcttga ttatcactgc ttaccaatct gcttcaggtg tcttgaactt
    26341 gattgcacca acatctggta ttgtgatggg agctcttgca cttggacgta tcaacattgg
    26401 tacttggtgg aaattcatgg gcaaactcgt agtcgctatt attgtagtga ccatcgccct
    26461 tcttctcctt ggaaccttcc ttccattcct ataaaatagt gagtgaggtg attccatgaa
    26521 aatagatata acaaatcaag ttaaagatga atttcttata tcattaaaaa ccttgatttc
    26581 ctatccttca gtactcaatg aaggagaaaa tggaacacct tttggacaag caatccaaga
    26641 tgtcctagaa aaaactttag agatttgtcg agacataggt ttcactacct atcttgaccc
    26701 taaaggttat tacggatatg cagaaatcgg tcagggagca gagcttctgg ccattctctg
    26761 tcatttggat gttgttccat caggtgatga agcagattgg cagacaccgc catttgaagc
    26821 aactatcaaa gacggctggg tattcggacg tggtgtccaa gatgataaag gcccttcgct
    26881 cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt attcagttca aaaagcgcgt
    26941 acgctttatc tttggtaccg atgaggaaac cctctggcgc tgcatggcac gctacaatac
    27001 catcgaagaa caggccaaca tgggctttgc acctgactca tcttttcctc tgacctatgc
    27061 tgaaaaaggg cttctacagg tcaaacttca tggccctgga tcggatcaac tagagcttga
    27121 agtaggaggc gcctttaacg ttgtaccaga caaggccaac taccaaggtc ccctctatga
    27181 acaggtttgt aacggtctca aagaaactgg ttatgattac caatccactg aacaaaccgt
    27241 aacggttctc ggagtgccaa agcatgctaa ggatgctagt caaggtatca atgctgtcat
    27301 ccgactagct accattcttg ctcctctcca agaacaccct gctctcagtt ttcttgcaac
    27361 acaagcaggt caagacggca caggaagaca aatctttggt gatatagcag atgaaccttc
    27421 tggtcaccta tcctttaatg tcgcaggtct catgatcaat catgaacgtt ctgaaatctg
    27481 tattgacatt cggactcctg tcttagctga taaggaagaa ctagtagagt tgcttacaag
    27541 atgtgcacaa aactaccaac tccgctacga agagtttgac tatctagcgc ctctatacgt
    27601 cgcaaaagac agtaaactcg ttagcacact gatgcaaatc taccaagaaa agactggcga
    27661 taacagtcct gctatttcat ccggtggtgc cacttttgct cgcaccatgc caaattgtgt
    27721 agccttcggc gccttattcc caggagcgaa gcagacagaa catcaggcaa atgaatgtgc
    27781 cgttctagaa gatttgtacc gtgctatgga tatttatgcc gaagccgtct atcgacttgc
    27841 aacttaatca ggcaactgtt tctaccaaaa aaaatcgacc gattaatgaa ctgcacccca
    27901 aaagttagac agaataaatc taacttttgg ggtgttttat tatgaaatt
//
LOCUS       DAVBNZ010000024        27700 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000024 DAVBNZ010000000
VERSION     DAVBNZ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27700
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.024"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            389..1567
                     /locus_tag="VQ860_001087"
     CDS             389..1567
                     /locus_tag="VQ860_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3119524.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            1881..2012
                     /locus_tag="VQ860_001088"
     CDS             1881..2012
                     /locus_tag="VQ860_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET3119525.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2033..3583
                     /gene="dltA"
                     /locus_tag="VQ860_001089"
     CDS             2033..3583
                     /gene="dltA"
                     /locus_tag="VQ860_001089"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET3119526.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3580..4824
                     /gene="dltB"
                     /locus_tag="VQ860_001090"
     CDS             3580..4824
                     /gene="dltB"
                     /locus_tag="VQ860_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET3119527.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4838..5077
                     /gene="dltC"
                     /locus_tag="VQ860_001091"
     CDS             4838..5077
                     /gene="dltC"
                     /locus_tag="VQ860_001091"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET3119528.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5070..6338
                     /gene="dltD"
                     /locus_tag="VQ860_001092"
     CDS             5070..6338
                     /gene="dltD"
                     /locus_tag="VQ860_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET3119529.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6493..6933
                     /gene="adcR"
                     /locus_tag="VQ860_001093"
     CDS             6493..6933
                     /gene="adcR"
                     /locus_tag="VQ860_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET3119530.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            6933..7637
                     /locus_tag="VQ860_001094"
     CDS             6933..7637
                     /locus_tag="VQ860_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3119531.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7630..8436
                     /locus_tag="VQ860_001095"
     CDS             7630..8436
                     /locus_tag="VQ860_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3119532.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8446..9951
                     /gene="adcA"
                     /locus_tag="VQ860_001096"
     CDS             8446..9951
                     /gene="adcA"
                     /locus_tag="VQ860_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET3119533.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11113..11886)
                     /locus_tag="VQ860_001097"
     CDS             complement(11113..11886)
                     /locus_tag="VQ860_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3119534.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            12062..13465
                     /locus_tag="VQ860_001098"
     CDS             12062..13465
                     /locus_tag="VQ860_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET3119535.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13580..14218
                     /locus_tag="VQ860_001099"
     CDS             13580..14218
                     /locus_tag="VQ860_001099"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET3119536.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14230..14670
                     /locus_tag="VQ860_001100"
     CDS             14230..14670
                     /locus_tag="VQ860_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET3119537.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14663..15094
                     /locus_tag="VQ860_001101"
     CDS             14663..15094
                     /locus_tag="VQ860_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3119538.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            15085..15555
                     /locus_tag="VQ860_001102"
     CDS             15085..15555
                     /locus_tag="VQ860_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3119539.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15580..16353
                     /locus_tag="VQ860_001103"
     CDS             15580..16353
                     /locus_tag="VQ860_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3119540.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16350..17150
                     /locus_tag="VQ860_001104"
     CDS             16350..17150
                     /locus_tag="VQ860_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3119541.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17209..19503
                     /locus_tag="VQ860_001105"
     CDS             17209..19503
                     /locus_tag="VQ860_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3119542.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19513..22629
                     /locus_tag="VQ860_001106"
     CDS             19513..22629
                     /locus_tag="VQ860_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3119543.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            22686..24452
                     /locus_tag="VQ860_001107"
     CDS             22686..24452
                     /locus_tag="VQ860_001107"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET3119544.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHTQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            24598..25749
                     /locus_tag="VQ860_001108"
     CDS             24598..25749
                     /locus_tag="VQ860_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET3119545.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            25894..26778
                     /locus_tag="VQ860_001109"
     CDS             25894..26778
                     /locus_tag="VQ860_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3119546.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(26896..26973)
                     /locus_tag="VQ860_001110"
                     /pseudo
     CDS             complement(26896..26973)
                     /locus_tag="VQ860_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            27177..27429
                     /locus_tag="VQ860_001111"
                     /pseudo
     CDS             27177..27429
                     /locus_tag="VQ860_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            27417..>27700
                     /locus_tag="VQ860_001112"
     CDS             27417..>27700
                     /locus_tag="VQ860_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119547.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQISERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVA"
BASE COUNT         8690 a         4542 c         5875 g         8593 t
ORIGIN      
        1 actcccctga aatttatttt aattatgcaa atttcacgta tttttgatgc tgagacgacg
       61 atcctgggaa cttttcagat atttttttga ctatctaaat ctatcattag aaaagcttag
      121 agcgccaaag gatttgagcg tttttctgat ttttaagact ttttccagtc tctttttcga
      181 ttgaagatgt aattattcta ctaactaact aacttcttag tactagccaa caacgataat
      241 cataattcct cctaaaatta ggaataataa aggcaatagt ttttgttttt tcatgtaaaa
      301 aacctcactt ttgttttctg ctattttatg ctaaaatatt aaaaatcaaa tttaattcca
      361 aagtttgtaa ctaaaggggg agcgctacat gtctaattca tttgtcaagt tgttagtctc
      421 tcaattattt gcaaatttag cagatatttt ctttagagta acaatcattg ctaacatata
      481 cattatttca aaatcagtaa ttgccacatc actagttcct atcttaatag gaatatcctc
      541 ttttgttgcg agtcttttag ttccgttggt tactaaaagg ttagcgctaa atagggtttt
      601 atctttatct caatttggaa agactatatt attggcgata ctggtaggaa tgtttaccgt
      661 aatgcaatcc gtagcgcctt tggtgaccta tctatttgtt gttgcaattt ccatactaga
      721 tggttttgca gcacccgttt cctatgctat tgtgccacgc tatgcgaccg atttgggtaa
      781 ggctaattca gccttatcaa tgactggtga agctgttcaa ttgataggtt ggggattagg
      841 tggactcttg tttgcaacaa ttggtctgtt acctaccacg tttatcattt tagtcttgta
      901 tatcatttct agctttctga tgttatttct tcctaacgct gaagtggagg tgttagagtc
      961 agaaactaat cttgaaattt tgctcaaagg ttggaagtta gttgctagaa atcctagatt
     1021 aagacttttt gtatcagcaa atttattgga aattttttca aatacgattt gggtttcttc
     1081 cattatactt gtttttgtaa cggagttatt aaataaaacg gaaagttact ggggatattc
     1141 taatacagca tactctattg gtattataat tagtggctta attgctttta ggctatctga
     1201 aaagttcctt gctgctaaat gggaaagtat tctttttcct cttgtagcta tggcaatagt
     1261 gacactgact attctatatt ttccaaacgc acagatgttt ttattatttt cagctttagt
     1321 tggtatgtta tcgcaactaa aagaagttcc tgaaagtgta tttcttcagg aaacagtaga
     1381 ggaaaatcat ttagttaatg tctattccgt tcttgaagtg atttctacat tagcattttc
     1441 agtatttgtt ttgctaatga gctatattac tgagagtttt ggtattagca tcagtttttg
     1501 gctatcagcc atttgtctga tgatagaagc tattttaatt tatatcagac gagattattt
     1561 taaatgagag agtggttaaa aagtctttaa aaatcagaaa agcgcatagt atcaggtgtt
     1621 gaaaaaactt gatattgtgt gttttattat gggaagattt acttcattgt ctcctgaaat
     1681 ggagttttga ggcaggatca ctctatttga aaatatacat agaaaaactg tataatcctt
     1741 aaaataagct gaaatctatt ggaaacatac ggtaaacaat tgaaaagata ctatataaag
     1801 tggtacaatg gtagaaaaat aagctagtaa gaatcactct tattttagcg aaaaattaca
     1861 gaaatgaatg gtttttcttg atgaaacaga gaaaagaatt gtacctcttt cttggtcgga
     1921 cagccttgta ttttcttatc tttctagggc tgctttactt ctttagctat cttggtcagg
     1981 gtcaaggaag ctttatctat aatgaatttt aacttgaagg agaatcccta ttgtgtcaaa
     2041 taaaccaata gcagatatga ttgaaaccat tgagcatttt gctcagacac agcctagcta
     2101 tcctgtctat aatgttttgg ggcaggaaca cacttatggc gatttaaagg ctgattcgga
     2161 tagtttggct gcagtcattg accaactagg cttgcctgag aagtctcctg tggttgtttt
     2221 tggtggccaa gaatatgaaa tgttggcaac ctttgtagcg ctgactaagt caggtcatgc
     2281 ctacattcca attgatagcc attcggcctt ggagcgagtt tcagctattt tagaagtagc
     2341 agagccaagc ttgattattg ccatttcagc ctttcccttg gagcaggttt ctacaccaat
     2401 gataaatcta gctcaggttc aagaagcctt tgcccaaggg aataactatg aaatcacgca
     2461 tccagtcaag ggagatgata attactacat tatctttact tctggtacga ctggtaagcc
     2521 taagggagtg cagatttcac atgataatct cctcagcttt acaaactgga tgattacgga
     2581 taaggaattt gcgacaccga gtcgtccgca aatgctggca cagccacctt attcttttga
     2641 cttgtctgtc atgtattggg caccgacctt ggcacttggt ggtacgcttt tcactcttcc
     2701 ttcagtcatc actcaggact ttaagcaact ctttgcggct atcttttcat tgccaatcgc
     2761 tatctggaca tcaacaccat cctttgcaga tatggccatg ttgtctgaat acttcaacag
     2821 tgagaaaatg cctggaatca cgcatttcta ctttgatggt gaagaattga cggtcaaaac
     2881 agctcaaaaa ctgcgcgagc gtttcccaaa tgcccgtatc atcaatgctt acggcccaac
     2941 agaagcgaca gtagctctgt cagcagttgc cgtgacagac gagatgttag cgactctcaa
     3001 acgcctacca atcggctata ccaaggctga ttctccaacc tttatcattg acgaggaagg
     3061 aaataaactg ccaaatggtg agcagggaga aatcattgtt tctgggccag ctgtttcaaa
     3121 aggttatatg aacaatcctg aaaaaacagc agaagccttc tttgagtttg aagatctgcc
     3181 agcctatcac acaggcgatg tgggaaccat gacagatgag ggcttgcttc tctacggcgg
     3241 acgcatggac ttccagatta agtttaacgg ttaccgcatt gagttagaag atgtctctca
     3301 aaacctcaac aagtctcgct ttatcgaatc tgctgtcgca gtaccgcgct ataacaagga
     3361 ccacaaggta caaaatctat tggcttatgt catcttaaaa gacggtgttc gtgagcagtt
     3421 tgagcgagat atcgatatta ccaaggccat caaggaagac ctgacagaca tcatgatgtc
     3481 ctatatgatg ccatctaaat tcctttaccg agacagtttg ccactaactc caaatggaaa
     3541 gattgacatc aaaggattga ttaacgaggt gaataagaga tgatggagtt ttttcaacag
     3601 cttcctcatt tagagccata tggcaatcct cagtattttg tttatgtgat tgctgcaacc
     3661 ttgcccatct ttataggtct ctttttcaag aaacgctttg cctggtatga agtgttggta
     3721 agtctcttct ttattgtcac catgttggtg ggtggaaaga ccaatcaact agctgccttg
     3781 ggtatttacc tttgctggga aatattgctc ctgcttttct acaagcatta tcgaaaaagc
     3841 aaggatggca agtgggtctt ctacttagtt agttttctgt ccctacttcc gattatcttt
     3901 gtcaaggtgc aaccagctat caatggaacg cagtctttgc ttgggttctt gggaatttct
     3961 taccttacct ttcgttcggt tgggattgtc atcgagctga gagatggagt gattaaggat
     4021 tttaccctct gggaattcct ccgtttcctt ctcttcatgc caactttctc gagtggtcca
     4081 atcgatcgct ttaagcgatt taatgaaaat tatcaggcta ttcctgagcg agatgagttg
     4141 atggatatgc tggatgaatc tgtccgctat atcatgtggg gctttttgta taagtttatc
     4201 ctagctcatg ttttaggaga gaccttacta cctcctctga agaatttagc cttgcagtca
     4261 ggtggcttct ttaatctcta tgccttggca gttatgtata cttttggtct ggaactcttc
     4321 tttgactttg caggttattc tatgtttgct ttggccatct caaacttgat gggaatccgt
     4381 agccctatca actttaacaa gcccttttta tcaagggatt taaaggagtt ttggaatcgc
     4441 tggcatatga gtctgtcctt ctggttccgt gactttgtct ttatgcgaat ggtgatggtg
     4501 ttaaccagaa agaaagtctt taaaaatcgt aatgtaacct caagcatggc ctacattgta
     4561 aatatgctga ttatgggatt ttggcatggt gtgacctggt actatatcgc ctatggactc
     4621 tttcatggac taggcttggt catcaatgat gcctgggttc gcaagaaaaa aacgctcaat
     4681 aaggaacgga aaaaagcagg gaaggctgcc ctacctgaga atcgctggat tcagttgctt
     4741 ggcatggttg tcactttcca tgttgtcatg ttgtcattct taatcttttc tggattcttg
     4801 aataatctat ggtttaaaaa ataaaaggaa ataaaatatg gatatcaaat cagaagttat
     4861 tgaaattatt gatgagttgt ttatggaaga tgtttctgac atgatggatg aagatctttt
     4921 tgatgcaggt gtcttggata gtatgggaac ggttgagttg attgtggaga ttgagaaccg
     4981 ttttgacatt cgtgtccctg taacagagtt tggtcgtgac gactggaata cagctaataa
     5041 aatcatagct ggtattgtgg agctacaaaa tgcttaaacg cttatggatg atcttcggac
     5101 cggtcttgat cgctggtttg ttggtttttc tgctcatttt cttttatcct actgagatgc
     5161 atcataatct aggagctgaa aagcgttcag cagtggctac tactatcgat agttttaagg
     5221 agcgaagtca aaaagtcaga gcactatctg atccaaatgt gcgttttgtt cccttctttg
     5281 gctctagtga atggcttcgt tttgacggtg ctcatcctgc ggtattagct gagaaataca
     5341 atcgttccta ccgtccttat cttttaggac aggggggagc tgcatcgctt aaccaatatt
     5401 ttggaatgca acagatgtta ccacagctgg agaataaaca agttgtgtat gttatctcac
     5461 ctcagtggtt cagtaaaaat ggctatgatc cagcagcctt ccagcagtat tttaatggag
     5521 accagttgac tagttttctg aaacatcaat ctggggatca ggctagtcaa tatgcagcga
     5581 ctcgcttact gcaacagttc ccaaacgtag ctatgaagga cctggttcag aagttggcaa
     5641 gtaaagaaga attgtcgaca gcagacaatg aaatgattga attattggct cgttttaatg
     5701 aacgccaagc ttcctttttt ggtcagtttt cggttagagg ctatgttaac tacgataagc
     5761 atgtagctaa gtatttaaaa atcttgccag accagttttc ttatcaggca atagaagatg
     5821 ttgtcaaagc agatgctgaa aaaaatactt ccaataatga gatgggaatg gaaaattatt
     5881 tctataatga gcagatcaag aaggatttga agaaattaaa ggattctcag aaaagcttta
     5941 cctatctcaa gtcgccagag tataatgact tgcagttggt tttaacacag ttttctaaat
     6001 ctaaggtaaa cccgattttt atcattccac ctgttaataa aaaatggatg gactatgctg
     6061 gtctacgaga ggatatgtac caacaaacgg tgcagaagat tcgctaccag ttggaaagtc
     6121 aaggttttac caatatagca gatttttcta aggacggcgg ggagcctttc tttatgaagg
     6181 acaccattca ccttggttgg ttgggttggt tggcttttga caaggcagtt gatcctttcc
     6241 tatccaatcc cacaccagct ccgacttacc atctgaatga gcgctttttc agcaaagatt
     6301 gggcgactta tgatggagat gtcaaagaat ttcaatagat aatataatat agaagagttc
     6361 aagaatgaaa ctagttttca cgttttttct tgactctttt tttgcttgtg atataattaa
     6421 ctggtaaaca aaatgtcaaa gaatagtatt tttctcttaa aaaagagaag tctaaaagga
     6481 aaggagtcag atatgagaca gctagcaaag gatatcgatg cttttttgaa tgaggtgatt
     6541 ttgcaggcgg aaaatcagca tgaaatccta ataggtcatt gcactagcga ggtggccctg
     6601 accaatactc aggagcatat ccttatgctc ttgtcagagg aatctttaac aaattcagaa
     6661 ttggcccgtc gtctcaatgt cagtcaggcg gcagttacca aggccattaa gtctttggtc
     6721 aaggaaggga tgttggaaac atctaaagat tctaaagatg cgcgtgtgat tttttatcag
     6781 ttgactgact tggctcgtcc aatcgctgag gagcaccacc atcaccatga gcatacactt
     6841 ttaacctatg aacaagtggc gactcagttt actccaaatg aacaaaaagt gattcagcgg
     6901 tttttgactg ctttagtagg agaaatcaaa taatgagata tattacggta gaggatttgt
     6961 ccttctatta tgataaggag cctgttcttg aacatatcaa ttattgtgtt gatagtgggg
     7021 aatttgttac cttgactggg gaaaatggag cggctaagac gacgctcatc aaggctagtc
     7081 ttggaattct gcaaccacgc attggaaagg tggctatttc aaagacaaat acgcaaggta
     7141 agaaattgag aatagcctat cttcctcaac aaattgccag ttttaatgct ggttttccaa
     7201 gtacggtcta tgaatttgtc aagtcgggtc gctatccgag aaaaggctgg ttccgtcgtt
     7261 tgaatgctca tgatgaggag catatcaagg ctagtctgga ctcagttggc atgtgggaac
     7321 atcgagacaa acgcttgggg tctctatctg ggggacaaaa gcagcgagcg gtgattgcgc
     7381 gtatgtttgc ttctgaccct gatgtgttta tcctagacga gccgacaacg gggatggatg
     7441 caggaagtaa aaatgaattt tacgaactca tgcaccacag cgcccatcat catggcaagg
     7501 ctgttttgat gattacccat gaccctgaag aagttaagga ttatgcggat cgcaatattc
     7561 atctagtccg taaccaagac tcgccatggc gttgtttcaa tgttcatgag aatggccagg
     7621 aggtgggcca tgcttagttt attatcttac gactttatac aacgcgcctt tttggcggtt
     7681 attgctatga gtcttttctc accggtattg ggaaccttcc tcatcttgcg tcgtcagagt
     7741 ttgatgagtg atacccttag ccacgtctca ctttcaggtg tagcctttgg tctggttttg
     7801 gggatttctc caactgtttc tactattgcc attgtcttga ttgcggcggt ctttctggag
     7861 tatctccgta cggtttacaa gagctttatg gaaatcggga cagctatcct catgtcaaca
     7921 ggtctggctg tttctctgat tgtcatgagc aagggtaaaa gctcgagttc aatgagtttg
     7981 gaccaatatc tctttggttc gatcgtgact atcagtgaag aacaggtcat ttccctcttt
     8041 gtcattgcgg cggttgtttt gattttgacc tttctctttc ttcgtcctat gtatatctta
     8101 acttttgacg aagatacggc ctttgtggat ggcttgccag ttcgtaccat gtccattctt
     8161 tttaacatgg tgacaggggt ggctattgcc cttatgattc ctgcagcagg agctcttctg
     8221 gtatcgacca ttatggtctt gccagctagt attgccctgc gtctggggaa aaactttaaa
     8281 tcggttatgc tgcttgccag tgcgattggc tttttgggaa tggtagcagg actttacatt
     8341 tcctactatg cagaaacacc tgcaagtgca agtattacca ttatttttgt aactgtcttt
     8401 atactaatca gtttagtaag acgttttatc aaataggaga cgaacgtgaa aaaaattagc
     8461 ttattactag ccagtctatg tgccttgttt ttagtggctt gttccaatca aaaacaggca
     8521 gatggtaaac tcaatatcgt gacaaccttt taccctgtct atgaatttac caagcaagtc
     8581 gcaggagata cggctaatgt agaactccta atcggtgctg ggacagaacc tcatgaatac
     8641 gaaccatctg ccaaggcagt tgccaaaatc caagatgcag ataccttcgt ttatgaaaat
     8701 gaaaacatgg aaacatgggt acctaaattg ctagatacct tggataagaa aaaagtgaaa
     8761 accatcaagg cgacaggcga tatgttgctc ttgccaggtg gcaaggaaga agagggagac
     8821 catgaccatg gagaagaagg tcatcaccat gagtttgacc cccatgtttg gttatcacca
     8881 gttcgtgcca ttaaactagt agagcacatc cgcgacagct tgtcagcaga ttatcctgat
     8941 aaaaaagaga cctttgagaa gaatgcagct gcctatatcg aaaaattgca agccttggat
     9001 aaggcttacg cagaaggctt gtctcaagca aaacaaaaga gctttgtgac tcaacacgca
     9061 gcctttaact atcttgcctt ggactatgga ctcaaacaag tcgcaatctc aggactttct
     9121 ccagatgcag agccatcagc tgctcgcttg gcagaattga cagagtatgt caagaaaaat
     9181 aaaatcgcct atatctattt tgaagaaaat gcctcacaag cccttgctaa cacactttca
     9241 aaagaagcag gtgtcaaaac tgatgtcctc aatcctttag aaagtctgac agaagaggac
     9301 accaaggctg gagaaaacta catttccgtg atggagaaaa acctcaaggc tttgaaacaa
     9361 acaacagacc aagaaggccc agcaatcgaa cctgaaaagg cagaggatac caagacagtc
     9421 caaaatggtt acttcgagga tgcagctgtc aaggaccgca ccttgagtga ctatgcaggt
     9481 aactggcaat cagtttatcc tttccttgaa gacggcacgt ttgaccaagt ctttgactac
     9541 aaggctaagt tgactggtaa gatgacccag gctgagtaca aggcttacta tacaaaaggc
     9601 tatcagacag atgtgactaa gattaacatt actgataata ctatggaatt tgttcaaggt
     9661 ggacaaagca agaaatacac ttacaagtat gtcggtaaga aaattttgac ttacaagaaa
     9721 ggcaatcgtg gcgtgcgttt cctctttgaa gccacagatg ctgacgctgg acaattcaag
     9781 tatgttcagt ttagtgacca caatgttgcc ccagttaagg cagaacattt ccatatcttc
     9841 tttggaggca caagccaaga agccctcttt gaagaaatgg acaactggcc aacctactac
     9901 ccagataacc tatctggcca agaaatcgcc caagaaatgt tggcgcattg atgagaaatc
     9961 gactagttca taagagctag tcggtttttt gatactagat ggctaacttc attatagacc
    10021 tttcagaact ttaaacaata aataaaactc ttgaaatatc tgggcttata tgctagaatg
    10081 tagttagtgt ataaggttca ttagaacacc aaagccccta actagtgcca tagttaaggg
    10141 cttttttgac gtatcttagc gatttaacgg gtgtttatag gctagtcagt cggtctactt
    10201 cttaccatct agccatttgc agacgaaata caagataatt ccagctataa catctgctat
    10261 aatagtaaga gcaagctctg gtataaggct cattagtttc acctcctctc acgaacccat
    10321 aggaacgtaa tcggtaaccg atgacaaaag tattatatca cactaaattt agatcatcaa
    10381 cctcacttaa tgcttgaact attgtagatt atatgctaaa atgtagttaa ttgataaggt
    10441 tcattagaac accaaagccc ctaactatgg ccgtagttaa gggctttttt gacgtatctt
    10501 agcgatttaa cgggtgttta taggctagtc actcggtcta cttcttacta tctagccatc
    10561 tgcagacgaa atacaagata attccagcta taacatccgc tataatagta agagcgagct
    10621 ctatgataag gctcattagt ttcacctcct ctcacgaacc cataggaacg taatcggtaa
    10681 ccgatgacaa aaatagtata ccacaataca tttagatcat caaggtcact taattcttga
    10741 aatatagggt ctaggcgaca aagtctttaa aatcagaaaa acgcataata tcaggtgtgc
    10801 aaaaacttga tactatgcgt tttattgtgg gaaggtttac tccattttct cctgaaattg
    10861 agtttttgtc cagcctctgt ttttagggtt gctgagaaaa taatgtcatg tggtgaatat
    10921 ttgtaaatca gtcagcagac agaacgaata ctcttcgaaa atctcttcac atcatgtcag
    10981 cttcgtcttt ccgtatatat gtgactgact tcatcagttc tatctacaac ctcaaaacag
    11041 tgtttcgagc tgacttcatc agttttcaaa tctgtacttt gagcaagctg agactagctt
    11101 cctatttgat tttcattgaa tatcagaaac ccattctcca tcaaataatt cgactgcgtc
    11161 taataatttt tgatctggca cggtgtctga aataaaggtt gtgtatttgg agaggggatt
    11221 aattttaaaa aatccagtct tgtaaaattt agaactatca atcagtaaga tggtttcatg
    11281 ggctttgtca ataatattct tttttgaaat agcttggctg agagaagctt cataaacata
    11341 ttggtcatca atacctcttg ctgaacaaaa tgctaaatcg atattaaaat gatctaataa
    11401 agaattttcc ttatcatagt tgaccacgga acaggattga tgtttgacct cgccagatgt
    11461 gataaagatt ttggagctat ctttaacagt ttcagatagg gtttgtgcag tatgtaaacc
    11521 atttgtaaaa ataatcaaat tatcaagttc agaaagatag ggacaaagtt cgtagacagt
    11581 agtactggaa tccagataaa cacacatacc agaccgaata aagtctttag cgagactagc
    11641 gattagtctt ttttgcctag tactttctcc ttcccgtatt tgatgagaaa gttcaattgt
    11701 gttcatagag gacagggtca cgtatccgtg ctttcttttg ataagacctt gattttctaa
    11761 gaaaattaaa tcacgacgta aggtacttgt gctggagaaa gtgatttctg ccagctcttt
    11821 tacggcaatt ctttttttct ttttaataat ttcaatcaat tcaagtacac gttcatcttt
    11881 tatcataagc tcctcctaat ttatcatttc aactatatta tagcacaaat tggaggaatt
    11941 tgaattattt ttatgaatat tgggttaaca tttgaacatt attcaagtaa gcgttcacat
    12001 attgaaaaaa taaaacgtgg ggattataat aaagttaatc aaggacgaag agagaagaaa
    12061 aatggaagcg gttttagcaa tagatttagg tgcgacttct ggaagagcaa tcgttggtta
    12121 cctttctgaa aataaactag taatggaaga aataaatcgc ttttctaatc tacctattag
    12181 agtaaaaggg catttatctt gggatattga ctttctacta gctaaaattc ttgaaagtat
    12241 ccgcttggct aatactagtt acaagatttt atctatcggt attgacacat ggggagttga
    12301 ttttggactg attgataatg aaggtaagct gttattacaa cctgttcatt atcgtgatga
    12361 aagaacaaag ggagtgttaa aggaaatatc tgaaatgact gaattagaaa aactgtattc
    12421 agagacagga aatcagatta tggagataaa taccttgttt caactcttta aggcacgtca
    12481 agaatctcct gactctttct ataagaccaa taagattctt ttaatgccag atttgtttaa
    12541 ttatctcttg acaggtaagt ttgctacaga aaaaagcatt gcttcaacaa ctcaattatt
    12601 tgatcctagg agtcaaaact ggaatcagaa tatcttaaaa ctatttgaat tggattcatc
    12661 tttacttcct gagattgttt cagagggaaa tgttcttgga aggataaaaa aggagtatgg
    12721 tttaggcgat attcctgttg tgaatgtttg tagtcatgat acagcaagcg cgattgtctc
    12781 agtacctaag acagaaggta gtttatttat ttcatcaggt acttggtctt tggttggagt
    12841 ggaacttact tcaccgcttc ttactaccga atccttcagt tatggattta caaatgaagt
    12901 cggtaaagat ggagtgatta catttctgaa gaattgtaca gggttgtgga tcatagagga
    12961 actaagacgt tcatttgaac gaagagggaa agcctattct tttgatgata ttaggacaat
    13021 ggtggagaaa gaaaaagaaa atcttcctct gattgatact gaatcaactg aatttgcaac
    13081 agaatctgat atgcacaaga ctttgacaga atatctagct tatcatcatg aaactagaga
    13141 gtggacagat ggacaactat ttaagattgt ttatgaaagc ctagctgaaa cgtataggaa
    13201 agcgatagag ttactagaag aactaactca taaggtttat aagaggatat atgtgattgg
    13261 aggaggtgct agagccagtt actttaacca aatgattgct gatagaactg gtaaagaggt
    13321 tcttacaggt ttgactgagg ctacagctgt ggggaatatt gttgtgcagc tcatagctat
    13381 gggacaatta aaagggatgg aagaggctca ccatgttatt gaggagtttc tacaattaga
    13441 gagttattac tcccaaaaga attaaaaaga ttgagagttt gtaaatttgc ctccctcccc
    13501 cttcttagct tttgtgcagg aaggggggat aattggtgaa ttgaaaaata tttagtgttt
    13561 tgatatgagg aggacaagga tgtcagatgt aaaacaagaa ttaattaaat atggtaagaa
    13621 gctagtagaa acagatttga cgaaaggaac aggtgggaat ctcagcgttt tcgatcgtga
    13681 aaaacaattg atggcaatta ccccgtcggg tattgatttc tttgaaatca aagaatccga
    13741 tattgtagtg atggatatta atggaaatgt tgtagaggga gaacgcttgc catctagcga
    13801 atggtatatg catttgattc aatatcaaac tcgtgatgat atcgatgcaa ttatccatgc
    13861 tcatacaact tatgcaacag tattagcttg tctcagagaa ccacttccag cgagtcatta
    13921 tatgattgca gtggcaggga aagatgttcg ggtagctgag tatgcaacat atggcacgaa
    13981 agaattggct gtgaatgcag ctaaagcaat ggaaggtcgt agagcagttt tactagcgaa
    14041 tcatggaatt ttagcaggtg cacaaaattt attgaatgca tttaatattg ttgaagaagt
    14101 tgaatattgt gcaaaaattt attgtttagc taagaatttt ggagagccag tagttcttcc
    14161 tgatgaggag atggaattga tggcagaaaa atttaaaaca tacggtcaga gaaaataggg
    14221 aggatattaa tgttaaaaca tataccgaaa aatatttctc cagatttatt gaagacttta
    14281 atggaaatgg gacatggaga tgaaatagta ttagctgacg cgaattatcc ttctgcctca
    14341 tgtgcaaata agctaattcg ttgtgatggt gtaaatattc cagaattatt agattccatt
    14401 ctgtatttaa tgccattaga tagttacgtc gatagttcaa ttcagtttat gaacgttgtt
    14461 tcgggtgatg atattcctaa gatatggggt acctatagac agatgattga aggtcatggt
    14521 acagatctta aaacgattac ttatcttaga agagaagact tttatgaacg tagtaagaaa
    14581 gcttatgcta ttgttgctac aggagaaact tcactttatg ctaatattat ccttaagaaa
    14641 ggagtagttg ttgaaagaga aaatgtttaa tagaggaatt ttagttgcca gtcatggtaa
    14701 ttttgctagc ggagctctca tgaccgcaga aatgtttgtt ggtgagacaa caaatgatag
    14761 agttaggaca ttaggtttga tgcctggaga gaatattgta gagtttgaac attattttaa
    14821 aaatcaagta aatgaactgt tagactcaaa tcaagaggtt atcgttttga ctgacttgat
    14881 tggaggaagt cctaataatg tggctttgtc acggttttta aatttggatt cagttgatat
    14941 tgtaacaggg tttaatatcc ctctcctagt ggaattaata tcaagttatg attcaaaaat
    15001 caatttagaa gaaattgttc aaaatgctca aaatagtttg tttaatgtta aacaacaact
    15061 taacgtagag gaggaagagg atttatgtct atagagtttg ttcgtattga tgaccgtctg
    15121 gtacatggtc aagttgtcac tacgtggcta aaaaagtatg atattgagca agttatcatt
    15181 gttaatgatc gcatctcaga agataaaaca cgacaatcta ttttaaagat ttctgcaccg
    15241 gtaggtttaa aaattgtttt ctttagtgta aaacggtttg tggaagtttt aaactctgtg
    15301 ccaataaaaa agagaacaat gctgatatat acaaatccaa aagatgtgta tgattctatt
    15361 gaaggaaatt taaaattgga gtacctcaat gtaggacaga tgagtaaaac ggaggaaaat
    15421 gaaaaggtaa cgggaggtgt agctctaggt gaagaagaca aatattattt taagaaaata
    15481 gttgataagg gaacgagagt tgaaattcaa atggttccta atgataaagt tacaatgttg
    15541 gaaaaatttt tataaaaata atttaaggag gtacagtata tgctattcac acaagcatta
    15601 ctggtgacat tagttgggat tattgccact attgactata atggaccgtt atttatgatt
    15661 caccgtccct tagttacaag tgcaatggtt ggcttagtct taggagattt cacccaaggt
    15721 gttcttattg gttcagctct tgaattaact tggctcggtg taacaggtat tggaggttac
    15781 actccaccag atactatttc aggtgcgatt attggtactg catttggtat tttatctggt
    15841 caaggagaaa ctgctggtat cgctatagca gttccaattg cagttgctac ccaacagttg
    15901 gatgttcttg caaaaacttt agatgtttat tttgtgaaaa aagctgataa tgatgctaaa
    15961 aacggagatt attcaaagat cggtttttat cattattcaa gtttggtttt aatcacgtta
    16021 tttaaaattg taccaatttt cctagctatt atgcttggag gggaatatgt ggcagacttg
    16081 tttgctaagg ttccaccaat cgttatgcag ggacttaact ctgcaggtgc tttactacct
    16141 tcaattggtt ttggtatgct tttaaatatg atgctcaaga aaaatatgtg ggtattcttg
    16201 ttgattggat tcatttgttc tgtgtatgga ggaatgtcaa ccattgggat ctcactagtt
    16261 ggtattgcgg tagcatactt ctacgatatg attggaagta aaccacaaga aacaacttca
    16321 agtagtgatg ttgaggagga tcttgatcta tgatgaataa taaagtaact aaagttgaac
    16381 ttaaaaaagt tttcaaacga agttttatgt atggttcttc atggaactat gagagaatgc
    16441 agaacctagg ttttctatat acaattcttc cagtattgaa aaaactatac ccagacaaag
    16501 attcagcttc tcctgcaatg aaacgtcacc ttgagttttt caatactcat caaacagcgg
    16561 caccatttat tcttggagtt acttccgcta tggaagaaca agaaggaaat gaaggtgcag
    16621 cttcaattac tggtattaaa gttggcttga tggggccact ggctggtcta ggagatagtt
    16681 tgttctggct gacactagtt cctatctgtt ttagtattgg tgcgtcttat tctaaagacg
    16741 gcggtgcttt aggtatcttt atcgccttaa tattgtttaa tattattaat attcctgtta
    16801 aatatttcgg tttgaaatat gggtatacta agggttctag tcttatccaa gaaaataata
    16861 caaaaggaac attgaatcgc gttacgagta tggcgacagc attagggcta gtactagtgg
    16921 gtggtttgat tccatcaatg gttggtatta attttggatt agaatttaag cagggggaac
    16981 ttgttatttc tgttcaagaa atgattacaa aattaattcc aggatttatc cctatggctt
    17041 tgactttatt aatgtgtaaa ttaattagaa aaggaaagaa tccggttgta ctaatcttta
    17101 gtgttatggc tattggagtt atcctagttg ttttaggaat tttgaagtag tagaaagtgt
    17161 ggaggtggta tttgggatat cacctccatt ttggaagaga ggtaaagagt gaaattatgg
    17221 tataagaaag ctgccgcaaa ttggaatgaa gccttgccga ttgggaacgg tcatttaggt
    17281 ggtatgattt atggttcagc tacaaaagaa tgtattcaac taaacgatga gactatttgg
    17341 tatagaggaa agtcagatag aaataatcca gactcactat tgcatcttaa aaaaattcgg
    17401 gaatatcttt tagatggaga aattcagaaa gccgaagaat tgataaagtt aacaatgttt
    17461 gctaccccaa gagatcaaag ccactatgaa ttacttgggg aactttacat tgagcatata
    17521 gatattcagt cttgtgctct ttcattgtat gaaagagagc tagatttaga tacagctatt
    17581 tctaatgttg tgtttgagcc taatagttgt aatttacaaa taaaaagaga atattttacg
    17641 agttttaata agaatatttt atgttgccgt atagtgtcat cagttcaaaa cacattaaat
    17701 ttaaacatta atttgggtag aaataaacgg tttaatgacg aagtatctaa actggattca
    17761 agtacaattt taatgtcggc ctctgctgga ggtagaaaag gtgttcagtt taaagtagta
    17821 tgtcattcta aggttacgga tggtgaagta agtgtattgg gagagacaat agttattcgg
    17881 aatgctacag aggtatttct ttatctcaaa tcaatgacgg attattgggg aaatatagat
    17941 atttcttctc ttcagggaga atttagtagt attgattact ttacagaaaa agatgaacat
    18001 gtaaaaaaat atcaggagca atttaataga gttgatttta aactagacta tagtaaaggt
    18061 tgtcttagca ttccaacgaa tctacttctt gaaaacacta aaaagtatag taactacttg
    18121 actaacttgt tatttcatta tggaagatat ctgttaatat cgtctagtca accgaatggt
    18181 ttacctgcca atcttcaagg aatatggtgt gatgaattaa atccaatttg gggttctaaa
    18241 tatacgatta atattaatac tcaaatgaat tattggatgg taggtccatg tgatttacca
    18301 gaagtagaat atccattatt tgatatgctc gaaagaatga gagaaccggg aagactaacc
    18361 gctaagaaaa tgtatggagc tagaggtttt acagcacatc ataatacgga tggttttggc
    18421 gatacggctc cccaatctca tgccatgggg gctgcaattt gggtattaac tattccatgg
    18481 ttatgtactc atatttggga acactattta tatttccaag atgagcgtat tcttacggaa
    18541 cattttgaaa tgataaaaga agcatttctt ttctttgaag attatttatt tgaggtggat
    18601 ggctacttga tgacaggtcc aagtgtctca ccggaaaata aatatcgctt aaaaaatggt
    18661 attgaaggaa atgcttgtct atcatctaca attgataatc aaattttaag atatttttgt
    18721 gattcatgca ttggaattgc aaaacaatta ggagacaatt cggattttat tagtcgtgtg
    18781 aaggagttaa aaaagaaact acctaaaaca aaaataggta gtaatgggca aatccaagaa
    18841 tggttagaag attatgaaga agtagagcct gggcatagac acatttcacc tctatttggg
    18901 ctttatcctt ataatgagat tgatattcat aaaactccgg aattagcaga agcagctaaa
    18961 atcactatca ataggagatt atcaaacgct aactttttat cttcacagga gagggagcaa
    19021 gcgattaata attggttagt aagtggtttg catgctagta cacaaacagg ttggagtgct
    19081 gcatggctga ttcatttttt tgcgagacta tatcaaggtg aacctgctta taaccagatt
    19141 aatggtttgt taaataatgc gactcttggc aatttatttc ttgaccatcc accatttcaa
    19201 attgatggta atttaggttt ggtgagtgga atttgtgaat tattagtaca gagccatcat
    19261 aattggttat cactaattcc agctttacct tctgcttggt cagaaggaga agtgaaaggt
    19321 ttcagagtaa gaggaggata taaggtatcg tttgcttgga aaaatgggga tataacattc
    19381 ctaaaattgg aaggaggaaa caaagatcaa aaagtaagag taagaatata tggcaaaaat
    19441 actgatgtac aaaatattga attggtattt aattcagaaa aaattattga gttaaatttt
    19501 taggtataag tcatgaataa agaaaaaata aaaagaaaat taatcacaat actgtttgta
    19561 tgtattggga tgttatgttt tggattgtta gcaggagtta aggctgataa tcgtgttcaa
    19621 atgagaacga cgattaataa tgaatcgcca ttgttgcttt ctccgttgta tggcaatgat
    19681 aatggtaacg gattatggtg ggggaacaca ttgaagggag catgggaagc tattcctgaa
    19741 gatgtaaaac catatgcagc gattgaactt catcctgcaa aagtctgtaa accaacaagt
    19801 tgtattccac gagatacgaa agaattgaga gaatggtatg tcaagatgtt ggaggaagct
    19861 caaagtctaa acattccagt tttcttggtt attatgtcgg ctggagagcg taatacagtt
    19921 cctccagagt ggttagatga acaattccaa aagtatagtg tgttaaaagg tgttttaaat
    19981 attgagaatt attggattta caataaccag ttagctccgc atagtgctaa atatttggaa
    20041 gtttgtgcca aatatggagc gcattttatc tggcatgatc atgaaaaatg gttctgggaa
    20101 actattatga atgatccgac attctttgaa gcgagtcaaa aatatcataa aaatttggtg
    20161 ttggcaacta aaaatacgcc aataagagat gatgcgggta cagattctat cgttagtgga
    20221 ttttggttga gtggcttatg tgataactgg ggctcatcaa cagatacatg gaaatggtgg
    20281 gaaaaacatt atacaaacac atttgaaact ggaagagcta gggatatgag atcctatgca
    20341 tcggaaccag aatcaatgat tgctatggaa atgatgaatg tatatactgg gggaggcaca
    20401 gtttataatt ttgaatgtgc cgcgtataca tttatgacaa atgatgtacc aactccagca
    20461 tttactaaag gtattattcc tttctttaga catgctatac aaaatccagc tccaagtaag
    20521 gaagaagttg taaatagaac aaaagctgta ttttggaatg gagaaggtag gattagttca
    20581 ttaaacggat tttatcaagg actttattcg aatgatgaaa caatgccttt atataataat
    20641 gggagatatc atattcttcc tgtaatacat gagaaaattg ataaggaaaa gatttcatct
    20701 atattcccta atgcaaaaat tttgactaaa aatagtgagg aattgtctag taaagtcaac
    20761 tatttaaact cgctttatcc aaaactttat gaaggagatg ggtatgctca gcgtgtaggt
    20821 aattcctggt atatttataa tagtaatgct aatatcaata aaaatcagca agtaatgttg
    20881 cctatgtata ctaataatac aaagtcgtta tcgttagatt tgacgccaca tacttacgct
    20941 gttgttaaag aaaatccaaa taatttacat attttattga acaattacag gacagataag
    21001 acagctatgt gggcattatc aggaaatttt gatgcatcaa aaagttggaa gaaagaagaa
    21061 ttagagttag cgaactggat aagcaaaaat tattccatca atcctgtaga taatgacttt
    21121 aggacaacaa cacttacatt aaaagggcat actggtcata aacctcagat aaatataagt
    21181 ggcgataaaa atcattatac ttatacagaa aattgggatg agaataccca tgtttatacc
    21241 attacggtta atcataatgg aatggtagag atgtctataa atactgaagg gacaggccca
    21301 gtccctttcc caacaccaga taaatttaat gatggtaatt tgaatatagc atatgcaaaa
    21361 ccaacaacac aaagttctgt agattacaat ggagacccta atagagctgt ggatggtaac
    21421 agaaatggta attttaactc tggttcggta acacacacta gggcagataa tccctcttgg
    21481 tgggaagtcg atttgaaaaa aatggataaa gttgggcttg ttaaaattta taatcgcaca
    21541 gatgctgaga ctcaacgtct atctaatttt gatgtgattc tatatgacaa taatagaaac
    21601 gaagttgcta agaaacatgt taataatttg tcgggtgaat ctgttagtct agatttcaaa
    21661 gaaaaaggag caaggtatat taaagttaaa ttactaacga gtggagtgcc tttgagttta
    21721 gcagaagtag aggtttttag agaatcagat ggtaagcaat ctgaagagga tatagataaa
    21781 ataacagaag ataaagtagt ctctacaaat aaggtagcta ctcaaagttc aaccaattat
    21841 gagggtgtag ctgctttagc agttgatggt aataaagatg gagattacgg acatcattcg
    21901 gtgactcata ctaaggcaga ttctaacgct tggtggcagg tcgatctggg agaagagttt
    21961 acggtttcta aagttgatat ttataataga acagatgccg aacctcagcg tttatctaat
    22021 tttgatgtta tttttctatc ttcatcagga gaagaagttt ttagaagaca ttttgataaa
    22081 gtagttgatg gtttgttatc tttaaaagta ccttctgtag gggctaagct agtcaaaata
    22141 gaattaaaat cagcagctat tccgttaagt ttagcggaag ttgaagtcta tggttcaaag
    22201 agaactccga agaaactttc taatattgca ttaaccaaag aaactcgaca gagttcaacg
    22261 gattacaatg gtttttctcg tctagcagtt gatggaaata aaaacggaga ttatggtcat
    22321 cattcagtga ctcataccaa aggagattct ccttcatggt gggagataga tttagcacaa
    22381 accgaagaat tagaaaagtt aattatttat aatagaacag atgctgaaat tcagagatta
    22441 tcaaattttg atattattat atatgattca aataatcatg aagtttttaa acaacatatt
    22501 gacagtttag aaagcaataa tctatccata gacttaaaag ggctgaaggg aaaaaaggtt
    22561 agaatttctt tgagaaacgc aggaattcct ttaagtttgg cagaggtaga ggtttatact
    22621 tataagtaat tttaaaaatt atcatcggta gtatgaaaga aacagaaaaa taagaggaaa
    22681 atagtatgat tcaacatcca cgtattggga ttcgtccgac tattgatggt cgtcgtcaag
    22741 gtgtacgcga atcacttgaa gtacaaacaa tgaacatggc taaaagtgtg gcagatttga
    22801 tttcaagcac attgaaatat ccagatgggg aacctgtgga atgcgtgatt tctccatcta
    22861 ctattggccg tgtaccagag gctgcagctt cccatgagtt gttcaaaaaa tcaaatgttt
    22921 gcgcaacaat tacagttaca ccatgctggt gttatggtag tgaaactatg gatatgtctc
    22981 cagatattcc tcatgctatt tggggattta atgggacaga acgcccagga gctgtctatc
    23041 ttgcagctgt actagcttca catactcaaa aagggattcc agcctttggg atttatggta
    23101 gagatgttca ggaagctaat gatacagcta ttccagaaga tgtcaaagaa aaacttttac
    23161 gttatgcgcg ggcagctctt gcaactggct tgatgagaga cactgcttac ctatcaatgg
    23221 gtagtgtttc gatggggatt ggtggttcta ttgtaaatcc ggatttcttc caagaatact
    23281 taggaatgcg aaatgaatcg gtagatatga cggagttcac acgccgtatg gaccgtggta
    23341 tttacgaccc tgaagagttc gaacgtgcgc tcaaatgggt gaaagaaaac gtaaaagaag
    23401 gattcgacca taaccgtgaa gaccttgttt taagccgtga agaaaaagat agacaatggg
    23461 aatttgttat taagatgttc atgattggac gtgacttaat ggttggtaac ccaagacttg
    23521 ctgaacttgg ttttgaggaa gaagcagttg gtcaccatgc tttagtagct ggtttccaag
    23581 gtcaacgtca gtggacagac cattttccaa atggagattt tatggaaact ttcctcaata
    23641 ctcagtttga ctggaatggt attcgaaaac catttgtatt tgcgacagag aatgattcac
    23701 taaatggtgt gtctatgctc tttaattatc tattaacaaa tactccacaa atctttgctg
    23761 atgtgcgtac ttattggagt ccagaggctg ttgaacgtgt aacaggatat actttagagg
    23821 gtcgtgctgc agctggcttc ttacatctaa tcaactctgg ttcttgtaca ttagatggta
    23881 caggtcaagc tactcgagat ggcaaacctg ttatgaaacc attctgggag ttggatgaaa
    23941 gtgaagtgca ggctatgctt gaaaatacag acttcccacc agcaaaccgc gaatacttcc
    24001 gtggaggagg attctcaact cgtttcttga cgaaggggga tatgccagta acaatggtac
    24061 gtctcaatct tctaaaaggg gttggtccag tgctacaaat tgcagaaggt tatacacttg
    24121 aacttcctga agatgttcac catactttag ataatcgtac agatccagga tggccaacta
    24181 cttggtttgc tccacgtttg acaggaaaag gtgctttcaa gtctgtctat gacgtcatga
    24241 ataattgggg agctaatcac ggagccataa catatggaca cattggagca gacttgatta
    24301 ccttggcttc tatgttgaga attcctgtca atatgcataa tgtacctgag gaagatatct
    24361 ttagacctaa aaattggtcc ttatttggaa cagaagatct agaatcagca gactatcgtg
    24421 catgtcagtt gttgggacca ctacataaat aaaacttgtt tatataggag gtgaacttac
    24481 gtccctccta tccttttaaa aagatttgtt aaacaattca caaataattg aaaacgaata
    24541 caaaaagtaa tataatgatg ttaaatagat agcgcggagg cgcaggagga aaattatatg
    24601 gctacatttt atgttccggc agtcaacctt attggaaaag gtgttgtaaa tgaagtgggt
    24661 ccttatatca aggaacttgg ctataaaaag gcacttttgg tgacagataa gtacatcgaa
    24721 ggcagtgata ttttacctaa gactttaaaa ccactggata cagaaggaat cgaatatgtc
    24781 atctttagcg atgtagagcc aaaccctact tgtaagaatg tcacagatgg ggtagctgct
    24841 ttgcaagaac atggatgtga ttttatcatc agtcttggcg ggggttctcc acaggatgca
    24901 gctagttgta tttctatcat ggctacaaat ggtggaaaac cacaggatta tgaagggctt
    24961 cataagtctg ctaaaaaagg cttgccagtt gtggctatca atacaacggc aggaacttct
    25021 gcagaaatca ctattaacta tgtgattact gatgaagaac gcaaggttaa gatggtaatg
    25081 gttgacaaga atagccttgc tcttatctct gttaatgacc cggaactcat gctttccaaa
    25141 cctaaaggtc tgactgctgc tactggtatg gatgctctga ctcacgctgt tgaagctttg
    25201 gtaacacctg gtgcttatga tgtaaccaag aaactgtcta ttggtgctat tgagcttatc
    25261 aaggaatatc ttcctcgtgc tgtagaaaat ggacatgata ttgaagcgcg tgaaggtatg
    25321 gtcaatgcca tcttccttgg tggtatgagc tttaataatg ctggtcttgg ttatgttcac
    25381 tcaatggctc accaactcgg tgcagtatat aatttgccac atggtgtttg ctgtgccatg
    25441 ttgctaccag ttatagaacg tgaaaatgct aaacgtgtac cagaagcttt ccgcaatgtt
    25501 gccaaagcct tgggccttca tgtggaaggt aaatcagatc aagagtgtgc cgattatgcg
    25561 attgctgaga ttgagaagct ttctgagaca gtaggtattc ctaagaaatt gactgaactt
    25621 ggtattgaag aaaaagattt cgactttgaa tacctttcta agaatgcctt gattgatgcc
    25681 tgcgcaccag gaaatccatt tatgccaacc ttagaagaaa cgattgcctt ttataaagag
    25741 ttattttagc aagagattag acgacaatag gacaattcac ctctaattat tgacatttca
    25801 ggaaaaatcg cagtaaaaac ggcacagcct tctttaaatg tgctataata ctagaaaaat
    25861 acttgtggag gttccattat ggcaatattt ttcatgattt ttctgattgt ttgtgtgctc
    25921 ctattggtga tagtcacact gagtacagtt tatgtggttc gtcagcagtc ggtggcgatt
    25981 attgaacgct ttgggaaata ccaaaaggtt gctaatagcg gtattcatat tcgcttgcct
    26041 tttgggattg actcgattgc agcacggatt cagttgcgct tgttgcaaag tgatattgtg
    26101 gttgagacta agaccaagga caatgtgttc gttatgatga atgtagcgac tcagtaccgt
    26161 gtcaacgagc agagcgtgac agatgcttac tataaactca tacgtccaga atctcagatt
    26221 aaatcttata tcgaagatgc tcttcgctct tctgttccaa aattaacctt ggatgaattg
    26281 tttgagaaaa aagatgagat tgcccttgag gttcaacacc aagtagcaga agaaatgacc
    26341 acttacggct acattatcgt gaaaaccttg attaccaagg tcgaaccaga tgcagaagtt
    26401 aagcaatcta tgaatgaaat caatgcggcg caacgtaagc gggtcgcagc acaagaattg
    26461 gcggaagctg acaagattaa aattgtcact gcagctgaag ccgaagcaga aaaagaccgc
    26521 cttcatggtg tggggattgc ccaacaacgt aaggcgattg tggatggatt ggcagagtct
    26581 atcaccgaac tcaaggaagc caatgttggc atgacagaag aacaaatcat gtctatcctc
    26641 ttgaccaacc agtatttgga taccttgaat acctttgcct ctaaaggaaa tcaaaccatc
    26701 tttttaccaa atactccaaa tggtgtggat gatatccgta cacaaatctt gtcagccctt
    26761 cgcgctgaga agaaataata gactaatact cttcgaaaat ctcttcaaac tacgtcagcg
    26821 tcgtcttgcc gtatagatgt tactgacttc gtcagttcta tctgcaacct caaaacagtg
    26881 ttttgagctg acttcgtcag tcttatctac tacctcaaaa cggtgttttg agcaacctgt
    26941 ggctagtttc ctagtttgct ctttgatttt cattgagtat aaagagcttg gcaacaggct
    27001 ctttttgtat tgcgtttatt aagaaaaaca aaaaacatcg atatacattt aactaaaaat
    27061 tattgtatgt tatctccctt aattaggaat gataagggaa taactagaaa gatttgtgaa
    27121 tacaaactat ttctgatata caaaatatac agtaataatg aatgatggga gatgggatga
    27181 aagaatttca atttgagaga aagcagcgtt tttctttgag gaaatatgca ataggagctt
    27241 gttcggtctt gctaggaacg agtttatttt tttgctggta tgggtgctca gcctgtacag
    27301 gatacagaaa cgagttcagc actaatttca agtcattatt tggatgagca ggatttatct
    27361 gaaaagctga aatctgagtt gcaatggttt gaattagaaa acaagctttt gaacttatgg
    27421 gagcattagg ttactatgaa ggatttgttc cttatgtttc aaatcaatac aaaaaccaag
    27481 ctgaagaaga aggcaaaccg ctatctgata aatatatttt cgaaaaaatc ttaggaaaaa
    27541 catatgcagc cttcaaaaaa gatcaaattt ctgagcgtgt cgagaaatta ggtaagttaa
    27601 aacctattac aataaattac aacggaaaat cagaagtaat tgatagtaaa gaaaaattac
    27661 aagagcttat gaataaagcc gttaaagacg aagtggctca
//
LOCUS       DAVBNZ010000025        27402 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000025 DAVBNZ010000000
VERSION     DAVBNZ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.025"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(1..432)
                     /locus_tag="VQ860_001113"
                     /pseudo
     CDS             complement(1..432)
                     /locus_tag="VQ860_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(508..1284)
                     /locus_tag="VQ860_001114"
                     /pseudo
     CDS             complement(508..1284)
                     /locus_tag="VQ860_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1208..1402)
                     /locus_tag="VQ860_001115"
     CDS             complement(1208..1402)
                     /locus_tag="VQ860_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3119548.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
     gene            complement(1572..1922)
                     /gene="tnpB"
                     /locus_tag="VQ860_001116"
                     /pseudo
     CDS             complement(1572..1922)
                     /gene="tnpB"
                     /locus_tag="VQ860_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1903..2088)
                     /locus_tag="VQ860_001117"
     CDS             complement(1903..2088)
                     /locus_tag="VQ860_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119549.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2392..3954)
                     /gene="guaA"
                     /locus_tag="VQ860_001118"
     CDS             complement(2392..3954)
                     /gene="guaA"
                     /locus_tag="VQ860_001118"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET3119550.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIRDIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4096..4794
                     /locus_tag="VQ860_001119"
     CDS             4096..4794
                     /locus_tag="VQ860_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3119551.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4837..5733)
                     /locus_tag="VQ860_001120"
     CDS             complement(4837..5733)
                     /locus_tag="VQ860_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3119552.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSAFTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5742..6677)
                     /locus_tag="VQ860_001121"
     CDS             complement(5742..6677)
                     /locus_tag="VQ860_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET3119553.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGSVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDEKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6674..7399)
                     /locus_tag="VQ860_001122"
     CDS             complement(6674..7399)
                     /locus_tag="VQ860_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET3119554.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLVSISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(7483..8118)
                     /locus_tag="VQ860_001123"
     CDS             complement(7483..8118)
                     /locus_tag="VQ860_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET3119555.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8120..8947)
                     /locus_tag="VQ860_001124"
     CDS             complement(8120..8947)
                     /locus_tag="VQ860_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3119556.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8969..9304)
                     /locus_tag="VQ860_001125"
     CDS             complement(8969..9304)
                     /locus_tag="VQ860_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HET3119557.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9305..9836)
                     /locus_tag="VQ860_001126"
                     /pseudo
     CDS             complement(9305..9836)
                     /locus_tag="VQ860_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10467..11078
                     /locus_tag="VQ860_001127"
     CDS             10467..11078
                     /locus_tag="VQ860_001127"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3119558.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11123..11851
                     /gene="rlmB"
                     /locus_tag="VQ860_001128"
     CDS             11123..11851
                     /gene="rlmB"
                     /locus_tag="VQ860_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET3119559.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11890..12801)
                     /gene="trxB"
                     /locus_tag="VQ860_001129"
     CDS             complement(11890..12801)
                     /gene="trxB"
                     /locus_tag="VQ860_001129"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET3119560.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12867..13091)
                     /locus_tag="VQ860_001130"
     CDS             complement(12867..13091)
                     /locus_tag="VQ860_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET3119561.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13169..13912)
                     /locus_tag="VQ860_001131"
     CDS             complement(13169..13912)
                     /locus_tag="VQ860_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3119562.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13912..14712)
                     /locus_tag="VQ860_001132"
     CDS             complement(13912..14712)
                     /locus_tag="VQ860_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3119563.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14870..15226)
                     /locus_tag="VQ860_001133"
     CDS             complement(14870..15226)
                     /locus_tag="VQ860_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET3119564.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15239..15751)
                     /locus_tag="VQ860_001134"
     CDS             complement(15239..15751)
                     /locus_tag="VQ860_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET3119565.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15751..16245)
                     /locus_tag="VQ860_001135"
     CDS             complement(15751..16245)
                     /locus_tag="VQ860_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3119566.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16380..16826
                     /locus_tag="VQ860_001136"
     CDS             16380..16826
                     /locus_tag="VQ860_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET3119567.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16823..17470
                     /locus_tag="VQ860_001137"
     CDS             16823..17470
                     /locus_tag="VQ860_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET3119568.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17491..18072)
                     /gene="pdxT"
                     /locus_tag="VQ860_001138"
     CDS             complement(17491..18072)
                     /gene="pdxT"
                     /locus_tag="VQ860_001138"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET3119569.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18073..18948)
                     /gene="pdxS"
                     /locus_tag="VQ860_001139"
     CDS             complement(18073..18948)
                     /gene="pdxS"
                     /locus_tag="VQ860_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET3119570.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19100..20479)
                     /locus_tag="VQ860_001140"
     CDS             complement(19100..20479)
                     /locus_tag="VQ860_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET3119571.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20773..21696
                     /locus_tag="VQ860_001141"
     CDS             20773..21696
                     /locus_tag="VQ860_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET3119572.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21756..22361
                     /locus_tag="VQ860_001142"
     CDS             21756..22361
                     /locus_tag="VQ860_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3119573.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFSDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22380..23624
                     /locus_tag="VQ860_001143"
     CDS             22380..23624
                     /locus_tag="VQ860_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3119574.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23847..24104)
                     /locus_tag="VQ860_001144"
     CDS             complement(23847..24104)
                     /locus_tag="VQ860_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET3119575.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24146..26182)
                     /locus_tag="VQ860_001145"
     CDS             complement(24146..26182)
                     /locus_tag="VQ860_001145"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET3119576.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEYFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26442..27359)
                     /gene="glyQ"
                     /locus_tag="VQ860_001146"
     CDS             complement(26442..27359)
                     /gene="glyQ"
                     /locus_tag="VQ860_001146"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET3119577.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEILLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
BASE COUNT         8078 a         6147 c         4999 g         8178 t
ORIGIN      
        1 gctaaaagag tccactggac tcttttactc cgtcccataa ccaatgattt aatggcgcgt
       61 tcagctagat tattggaaag gaccagatgt ccgtctttta aaatggtctt aaaggtttct
      121 ttatacttga ggctgtattc aattgccctt cctagttttg aacctgctaa aactgactga
      181 cggcggcacc aagcaaagaa gtcttccatt aggggctgga cgtttctgta gtcgttcatc
      241 agctggcaaa gcctcccagt ctctttccaa ggcaaataac tggtcacgat aggctaaacc
      301 tttagctcct aaggatgatt tatctgcttg cttgggggtc gcttcaaaaa atttccttct
      361 cacatgcgcc caacatccaa caagttcagc ttcttccagt tgacgataag cttctagcgg
      421 ttcgcagttt accaagctta gcgtcgcctt gctcctaaac cttagactgc tatcgcatag
      481 gcagaactag aggactaaag ttctaagtta ctgccgcaac atatcacaat gcatatagcc
      541 agaataattt cctaggaatt cttgcactac cgaaccactc cgacgctgat catggtggta
      601 cagcgtaatc ccttgtttct cagctttccc agacaaaaaa gtccaatagt aagtcagctg
      661 actatcactt tctaagaccc gataagaggt ttcatctgca tgaagaagag cttgttctaa
      721 caacttttct cgtaaaaggt tataaaggga ctctaaatag tattgactcg ccttgatatg
      781 ccaattagca atttccttac gtgtgattgg taaacccatc ttagcccaat cttcttctta
      841 gcgataattg ggtaccttca gaataaactt ctgatggatg gtgtgagcga taatagaagc
      901 tgagccaagg ctatgcgcca aaggggcttt aggaatagga gctttcacga ttttatcact
      961 tggattattc ttactgcatg tttggcattt gtaagcgtgt tggatatgat tcactctttt
     1021 taattgcgca agaataaaga ccaattcttg tcgttgaagg ctcgctccaa tctcttttag
     1081 ctctccctga cagtcagggc aaatgcagtt ctctaagcga tgatgaactt cttctgaatc
     1141 aaattgggca agaatagctt gacgtttccc tttagctttc ttacgtttat aggtgatttc
     1201 ttctctttca actgggtaag tcagagtctt cttccatatt ttgttcctct tcaaaaagac
     1261 tgagttgtcc agatgggcaa acacttttct cagaggattt tccatagagc ttttgcgtta
     1321 gataagccac ttgttcacga agaagggcaa gttcattggt gagactatca attgtagcac
     1381 tctgttgttg aatgattttc aatcttctcc catagacttt cctccttatt tcctaacttt
     1441 attatatagt gtattgaatc tataacagta caccttgact gctaaaatat ttctataaat
     1501 taatttgact ttcctgatag agatgttcat atcttatttc aattcactat actaaaaaga
     1561 aagtcctcat ttcaatagaa atcacgactt tctgatgaat ttatttttgg agtgatagaa
     1621 aagcccttca taagccagtc tacttgttca ggtgtgagag ctttgacatc cttttctgta
     1681 ctgggtcaag tcagtctgcc gttctcaaag cgtttatata gtagccaaaa tccttgacca
     1741 tcccagtaaa gggctttaaa gcggtcttta cgtccaccac aaaagagaaa aacttgaccg
     1801 gagaaaggat ctaattcaaa gtgggtttta accagataag ccagtgaatc aatgccttgc
     1861 ctcatatccg ttttcccaca tacgagatag acctgcccta ggctagatag atgaattgtc
     1921 atagagcaac accttatcca aaagctgttc taccatttcg agattgagag attgaaaaaa
     1981 acttacttca agcttgccaa tacgaatttt aagcagaata tcatttctct ttttagaatc
     2041 aaaaggacga gattgtggaa tctctacagg aacaataggt tgtggcatta aaatatcctc
     2101 caatagtttt actttactaa tagtatacag gaggagctcc atgaatgata gataccttgt
     2161 tatgacgcgc ttaccatatt agaaagttgg ctctctaatt aaattaattc tcattatata
     2221 tatcaaaaga ccgcagtttg aaaactacgg tctaattttt tgtccaaatg taaaccactt
     2281 ggaactatta ttcaatttat tctttttagc aaatgttccc gttttaatcc cagttacagt
     2341 ttttaatcct ttgtaaccgt tgattttaca aagcttttaa tttttttgcg attactccca
     2401 ctcaactgtt gcaggtggtt tacttgtaat atcgtagacg atacggttaa catgatccac
     2461 ttcatttacg atacgtactg agattttttg aagtacttcc catggaattt tggcaaaatc
     2521 agcagtcata ccatcgatag aagtgatagc acggattgca atcgtgtagt catacgtacg
     2581 accgtcaccc ataacaccga ctgaacgaac gcctgtgtta acagtgaagt attgccaaat
     2641 atcgcggtca agtccagctt tagcgatttc ttcacgaaga atagcgtctg attcacgaac
     2701 ggtttcaagt ttctcttcag tgatttcacc catgacacgg atagcaagtc ctggtcctgg
     2761 gaatggttgg cgccatacga tatggtctgg cataccaagc tctgtaccaa gagcacgaac
     2821 ttcatccttg taaagagtat tgagtggttc aatcaattca aactgcatat cttctggaag
     2881 accacccacg ttgtggtgtg acttgatagt ttgagctgta tccgtaccag actcgataac
     2941 atctgtatat aaagtacctt gagcaaggaa tttcacatct ttgagcttgc ttgcttcgtc
     3001 atcgaataca tagacaaact cgttaccgat gattttacgt ttttgttcag gatcagaaac
     3061 gccagcaagt ttgtcaagga aacgtttagc agcgtctgct ttgacgatat tcaaaccaaa
     3121 cttaccaccg agcatgtcca taacttgatc agcttcgcct ttacgaagaa gaccgtggtc
     3181 cacgaagata cagatcaatt gatcgccaat cgctttttgg agaagaaccc caacgacaga
     3241 tgagtcaaca ccacctgata gaccaagaag gacacgttta tcaccgacgg tttcacgaat
     3301 ttttttgatc tgcatgtcaa tgaaattatc cattgaccag tcacctttag ccttacaaat
     3361 gttaagggca aagttacgaa ggatatcatt tccgtataca gaatgacgaa cttctgggtg
     3421 gaattggata ccgtaaatgt gtttatctgg gttttcgatg gctgcgtatg ggcagtcagc
     3481 tgatgtacct gtacgaacaa agtcagcagg aatctcagta accgcatcac catggctcat
     3541 caaaacagtc tgttcatcag gtgttgattc aaaaagcgct gatggtgtgt gagttagggt
     3601 tgattgaccg tattcacgat ttccagcatc acctgcagga acaacttttc ctccaagttt
     3661 atgggtcaat aactgcatac cataacagat tcccaaaatt ggaattccga gttcgaagat
     3721 ttctgggtca atatcaaatg aaccatcttc atatacagaa tttggaccac ctgatagaat
     3781 aattcctaca ggattgactt cacgaacttc agcagctgaa attttatggc tttttagttc
     3841 tgaaaaaaca ccaatatcac ggatacggcg tgaaatcagc tggttgtact ggctaccata
     3901 gtccaatacg atgatttttt ctacatcttg caaatcagtt gaaatgttgc tcatcttttt
     3961 cctttctcaa aagaaatatc ttttctcaat attctatcac aaataagggc gaattaccaa
     4021 ctaaacaagg cgaagtttga ctttttctag tttattgggg tacaatagag aaaagataga
     4081 aatgaagtga aaaatatgct acctgcttat atgaaaatcc atgatcagat aaaaaaggat
     4141 attgacgagc accgttgggc tattggtgag aggcttccca gtgaaagaga tttagctgag
     4201 cagtttgcgg tcagtcgcat gaccctccgc caagccgtat ctctattagt cgaagaaggc
     4261 gtcttagagc gccatgtagg aagcggcacc tttgtttcca gtactcgagt acaagaaaag
     4321 atgcgaggga caaccagttt tactgaaatt gtcaaatccc aaggtaaagt tccctctagc
     4381 cagctcattt cctacaaaaa aaccattccc aatgagcaag aagttgccaa gctaggaatt
     4441 tttccaacgg acaatattat ccgaatggag cgggtccgct atgccgacca agttccccta
     4501 gtttatgaag ttgcttctat tcctgaaaaa ttcattaagg actttaaaaa agaagaaatc
     4561 accagtcatt tcttccaaac cttgcaaaaa catggctatc gtatcggcaa atctcaacag
     4621 accatctatg ctcgccttgc taaagaaaag attgcccact atttggaagt tgaaaaagga
     4681 catgctattc ttggattgac ccaggtttcc tacctagaag atggtactgc ttttgaatac
     4741 gtaaaaagtc aatatgtagg cgaacgcttt gaattttatc ttgaaaataa ttagattacc
     4801 acgcaaaaac tctctgtcac ggacaaagag tcttttttat ttttctaaga ataaatcttt
     4861 caaagaaatc aaagttacag caaacaatat cattgccata ccaagaaaat caatgggata
     4921 aaattgttca ttcattatta agaaggcaaa gaaaatcgcc gatattggct caattgaagc
     4981 caacaagctt gacttgaccg gtcctatcag actggctcct ttaaggaaag ctgtataggc
     5041 aaagacagtc ccgataagga taatgcctgc aaacgcaagg agaaaatcaa gactagtcgg
     5101 gatatcggcc tgtagaaccc ctgtaaaagg aagagcgacc aaacctgcta tgaccattcc
     5161 cacaccaatg accaagctgc tcccccactt tttaatcaag gctatgggta aaatgatata
     5221 cagagcataa gtaaaggcag aaaagagacc ccagaacaga ccagcaggtg tcatggataa
     5281 ctggtccaac tgcccatgtg ttgcgatcag gaaggttcct ccgatggcga atatgatgga
     5341 aactatctct cccagtgtcg gtgccaccct atccttgata cagctataaa ttaaaattcc
     5401 gacaggacaa acatactgaa gcaccgtcgc tgttcccgca ttggtctcct gaatagcaga
     5461 cagataggcg aattggttga gaaaaagacc aatcagagca aaaataagaa gagacagcaa
     5521 actctttcta tcctttaaaa agaccagtat tttatccttt gcagtagcat aagccaagag
     5581 catgagaatt ccaccagcga ttaaaagacg caagttggtc aagaccagag ccgaaattcc
     5641 gtgtgccatt aggtattggc cactcgttcc tgacaacccc caagcaatac cagccacaac
     5701 tgttagtaaa gtccctttta aactatttga catgtctctc cttactcttc tttgcgaatc
     5761 aagttcatca cttgattgcg gtctaatatc cattgagctc tctcgtcctt ttcataggta
     5821 cgattcgata ggaaaatagt ggcttcttgc ttctgacgat tccacatgat aaaggtacct
     5881 gtatagcccg tatggtctag ccaatctcct tccaaattcc atgctaaaga acgttccttt
     5941 tcatccaaag gagaaaaatt ttgacttaag tctcttgcaa aatcatctgc taaatagtgt
     6001 tctaaaaaga tttgtaaatc ctttatagtc gaaaataaac cagcactccc agcatgtcta
     6061 cccaggagac gagccttggg atcatgcact atgcctgcct ctacacctct aactgttgga
     6121 acagcaagct caactgaccc aaacttggtt tccgtcattc cccaaggttt ccagacttga
     6181 tcctttaaaa tcacatccaa atcttgatta aaaattcttt ccaaaataaa gcccaacagc
     6241 aaaaaatgga catccgaata aagaaaggct ggctgacttc gtctgttgag atgaaacatc
     6301 gcttccttta attcaggggc tgttaaaaga tcacgattag gaataaaagg atcaaggtct
     6361 gttgcatgag tcaagagctg gcgaatagtg atgtctggat aatcactctc aggtaaaaaa
     6421 tctattacca gtctatcaat atctaattga cctatttccc acaagaaggt acaaactgtg
     6481 ccaaccccaa caaccttgct gacactagct aggtcataaa ctagtcctgc ctcagtctgc
     6541 aagccatgct ctgggtcact ctggcctaaa tagaactctg tccattgatt gtccttaaaa
     6601 tacgcaaaag aggctccggg ataaattcct gcctcgattt gttcttctat ttttttaata
     6661 atcttggtcc acttcatact tcttcaaacc acaattcaac attatttcta tctttacaaa
     6721 ggaagaattt ttcagactta ggaataaaat attcagtaga ctcaaacttc tggcgaagac
     6781 ttgctatgtc taattcattg accaagaact tgagcataga taagtcccag gtaaccgtat
     6841 tgtccacagt caaatcctgc ccctgagctg gaataaaatc aagggatgcc ccaatttcag
     6901 atgattccaa gaaactttcg atatcagttg ggagatgtaa ttccatagaa atctcaaatt
     6961 tacttaaaga aattgatacc aaatctgttt gaaattcagg cttttctcct acttctacta
     7021 gacttgctct gtcatcttcc gcatgaatca aaatcaaatc atcttctggt gagaaaattt
     7081 caaaagcgta gccattttga cctttatata atcgatgaat cgaatctgtt ttagataaga
     7141 ttccttcaat ttctaaggga ttttccacct tgacaatcaa tctagctagt ttttttcttc
     7201 cctctacctt acgagtacgc atactgggag cttcttctaa aaccagcttt tcaagacccg
     7261 tttggtcacc tagtgacaga aaggccgatt cttctaacaa ggccttcatt ccaagggttt
     7321 caatataaaa tgtttcattt aattttctat tattagcttt taaagtagga ataatccgta
     7381 caatctgatt tacattcata aattcctccg tcacttttta ttttaaagga ttttagaatt
     7441 ttttacaaga tattatgctc aaatttaaca ttatttagct atttagtaaa gatagtcttt
     7501 caaggctttt gacaaagcct gataaccagc aatactgagg tgcagtccat cagttgtata
     7561 ttcttttttg agttggcctg cttggtctgt caaacaatca aatactggca caaattccac
     7621 ctgcatatag gcagatgcaa gctcttgata ggcttgattc cagttctgaa ttttttcatt
     7681 cgagcggata tagactgcct gctggtactc ctctccctca ttgacaggca aaatggaaag
     7741 caatttaatc tctgtcaatg gataatcgcg agcaacggat tgaatgatag cttcgagatt
     7801 attgagagcc tcattcacag gaacatcctt tccgatatca tttgtcccaa tcagaagaaa
     7861 aattttatct actgctccac catatagatg agcatcaagg ttctctagta acagtcctgt
     7921 ctgatagcca cgaattcctc gattgacaat cgtctttgaa gtcccaaata gctcctgtag
     7981 aggataatac tcgacaatgg aatccccaat aaaaagaatg tttggttcta caacagaaat
     8041 gtgatttagg tgacgatact tagtttgaat tttttcttgt tcctttagga gccaattttc
     8101 taataactgt actgccactt cattctcctt tttctaacca gttttccaag acttgataaa
     8161 ctcctccttg gctgttggct ggtgctagag cagtcgccac agctttggct ttctcatcag
     8221 cattttccat cgcataggca attccagcca tttcaagcat ttcaacatca ttttcactat
     8281 caccaaaagc catgatttct tgggatttca agtcccagcg cttgagtaat tcctccaagc
     8341 cccatgcttt atgaatccca gcttggagga tatcaatgca accatagcca ctggatacag
     8401 ctcggacacg gccatcaaag agagcattga tttcttccaa aaccgaactc aaacgttcct
     8461 caccaacaac catgctcatc ttgagcacac caccaaagag gtcagatgtt aattcatcca
     8521 caaattgcat ccgttggtag aatttttcaa tcatttctgg agtcataaaa ctttcaagat
     8581 ctgtaaaaat cgtaccttcc ttgacaaaat cacccttcat ccccgttaca acaaactggt
     8641 cctgacacgc tcgacccttg aaatgagtca aagccttgtt gacaatggcg tcatcccatg
     8701 tctgagcctg aatcaattca ttgttttcaa aaatacgagc gccattagca acaaccagaa
     8761 ccactcgatc caccaaggga ctcagtagtt gtctcatgcg gtgaatttca ttgcccgtcg
     8821 caatgacaaa acgaatgccc ctttgatcca actgatctaa aatcttttcc aatcgtggga
     8881 gatcaagctg acctctagca tccagcaagg tcccatccat atctgtcgca attaccttaa
     8941 tcatcattta ctttcctctg gattcaagct aataccactt caatcccaca tgttcattca
     9001 tttctttata ggctgtatca attcgttcct tagtcgcttc atctaactgg tcacgatgac
     9061 tgccatcctc tataaaatct tccaaaatat aagtttggta atgatacaag ggatatcctt
     9121 ctggtgaaaa ggttcccttt ggtgttcgat tgacccaagt aggatgagct ttagctgttc
     9181 cgatagttgt ttttccatcc ttcttcttga tggtgacatc catgagaaca ccacgttcag
     9241 tccacttagc attctcttca tctcccatag attcaatccg ttgattggaa atgaagttcc
     9301 ccatttaata gacaatgagc ttcttatctc catctttttc caccgtttca gatggttcaa
     9361 caacgtgagg atgccctcca aagataatat ccgctcccca atcgatcatc ttgtgataaa
     9421 gagctttttg ttcttcagtt ggttccaatc gatactcaac acccatctga agcatgataa
     9481 tggtgatatc tgcttccttc tctgcccgtt caatttcaac cttcatctta tcttcgttta
     9541 aatctgaaag ataacgatta tagtcttcct gagaaatata ctgctcaatt ccattgaaac
     9601 cataggaata ggctaacaat gcaaccttga taccattcac ttccttaatg accagcggag
     9661 cctgaacacg tggttcgtgc gtataaactc cgattggagt gattccagct ttctcaataa
     9721 tatcggccgt tgaaataact ccctcaagtt gaaataactc cctcaagttg cgaatccaaa
     9781 atatgattat gagctaaatc cagcacatga taacctgcct ccttaatagc atccataact
     9841 tcagcaggag cattaaagag aagataaccc gctaaataat gatccttatt aatggttcct
     9901 tcaaaatcac caatagctaa atctgcttgc ttgagccaag gagtcacata ctcaaaattt
     9961 tcatgaaagt cataggtacc gtcttctttt ttagctgaaa agaaaagtcc atcgtggtag
    10021 agcaaatccc cgtgggccat aattctggca gttttttcct cttcctactc ctgagacttt
    10081 tgcttagtcc cctcttgaga aatagtatct cgtttttgac tagtcaaggg attccttgga
    10141 agctttcaaa caacaagacc aagcccttca taaaacgaaa agctaaacca ccctgatttc
    10201 gattttatct tctttgtatc ttcattctcc ctactttctt atgcaagcct tttcttttta
    10261 ttatatcaca gataagtatt tctttcacaa ttgaattgaa cttcccatct attttctata
    10321 aatcctaaat gccataatgc tttcaattct tgtcattttg tgatatcatg tagaggaaat
    10381 gaactaatcc acagtggctt atttcaagta taccacttgg gctttggcag tagctaactg
    10441 cactaaatat aatataagga gagaaaatgt ctgcaataga acgtattaca aaagctgctc
    10501 acttaattga tatgaacgat attatccgtg aagggaatcc tactctacgc gcgattgctg
    10561 aggaagtcac tttcccccta tctgaccagg aaatcatcct aggcgaaaag atgatgcaat
    10621 tccttaaaca ttcccaagac cctgtcatgg ctgaaaaaat gggactccgc ggtggtgttg
    10681 gactggctgc tccccagtta gatatctcaa aacgcattat cgctgttttg gtacctaata
    10741 ttgttgaaga aggcgaaact ccacaggaag cctacgattt ggaagccatt atgtacaatc
    10801 caaaaatcgt ctctcactct gttcaagatg ctgctcttgg cgaaggagaa ggttgcctgt
    10861 ctgttgaccg taacgtgcct ggctatgttg ttcgccatgc ccgcgttact gttgactact
    10921 ttgacaaaga tggagaaaaa caccgtatca aactcaaagg ctacaactcc attgttgttc
    10981 agcatgaaat tgaccacatt aacggtatca tgttttacga tcgcatcaat gaaaaagacc
    11041 catttgcagt taaagatggt ttactgattc ttgaataaag aaaatcccgt tgcaagacgg
    11101 ggttttgtgt tataatagag gcatgaaaac aaatgatatt gtctatggcg tccacgccgt
    11161 taccgaagcc ctccttgcaa atacaggaaa caaactctac ctccaagaag atctccgagg
    11221 taagaatgtt gagaaagtca aggaactagc tacagaaaag aaggtgtcca tttcttggac
    11281 atcaaaaaaa tctctctctg agattactga aggtgctgtt catcaaggtt ttgttctacg
    11341 agtgtctgaa tttgcctata gcgagctaga ttacatcctt gcaaaaacac gccaagaaga
    11401 aaatccactt ctattgattc tagatggtct aaccgatccc cataatctgg gttctatctt
    11461 gcgaacagcc gatgcgacca atgtttcagg tgtcatcatt cccaagcacc gtgctgtcgg
    11521 agtaactcct gtcgttgcca aaacagccac aggtgctatt gaacacgttc caattgcccg
    11581 agtgacaaac ctcagtcaaa ccttagataa actcaaggat gaaggcttct ggacctttgg
    11641 aacggatatg aacggtactc cttgccacaa gtggaataca aaagggaaaa tcgccctcat
    11701 catcggaaat gaaggaaaag gcatctctag caacatcaaa aaacaggtcg atgaaatgat
    11761 taccattccg atgaatggac atgttcaaag cctcaatgcc agtgttgctg cggccattct
    11821 catgtacgaa gtttttctaa atagactata aaaaagtttc cagtcatctg attggaaact
    11881 tttttataat taactatgtt ctgtgataaa cttgtaggct tcttgaccag cgatagctcc
    11941 atctccaact gctgttgtta cttggcgaag gtctttcaag cgaacatctc caactgcaaa
    12001 gataccgtcg actgcagtct tcatgtggct atcagtcaca atccagcctg cctgatcttg
    12061 gatattcaat tctttaacaa aatcgctaag agggtccaaa ccaacataga taaagacacc
    12121 accgaaggct tgctctgtca cttgacctgt tttcacattt tcaaaaacga cagattctac
    12181 tctgttttca cccttgattt ccttcactac agaatcccag ataaagctga ttttttcatt
    12241 cgcaaaggcg cgatcttgta aaaccttttg ggcacgaagt tggtcacgac ggtgaacaat
    12301 ggtaacagtc ttagcaaaac gagtcaagaa gagggcttct tcaacagctg aatctccacc
    12361 accaactacc aataaatctt ggtcacggaa gaaagcacca tcacacacag cacagtaaga
    12421 aacaccacga ctgttcagtt cttcttctcc aggcactccc aaaggacggt gtttagaacc
    12481 agttgctacg ataactgtac gtgtttcata tgtttggtca tcagtcatca ctttcttaaa
    12541 atcaccatgg tcttcgacat tttcaacata accataaatg tgctcaacac caagattttc
    12601 aagtggttca aacatctttt cagccaattc aggtccacta atattagcgt atcctgggta
    12661 attttcgata tcagatgtat tattcatctg accacctggc agaccacctt caatcaaagc
    12721 tacttttaga ttgcttcgag cagcatacaa ggccgcagtc atccctgcag gtccagcacc
    12781 gataataata gtatcgtaca tatagattcc ttctttcttg ttgtaactat ctttattcta
    12841 actctttctt gtcaatcacg caaggattat gccttgaaaa caagaattaa actcataacc
    12901 gcaaaggata atactgggac aaccaagact ccaatcataa tcatatcata gagatgggct
    12961 tggcgagccc tggctgtctt atcaactccc gacatggctc tcagaccaat ccaaatccct
    13021 aaaaaaatca gaacaaggat ggtggtcaag atcaaactct cgaaatataa agaaaatagt
    13081 tgcagtagca tgatttctct catttctatc ttttttaaag agtaaactca gctagtccaa
    13141 ctaactgagt tttcctttat ctattatatc aaatataagt ccgtttgtaa ctagcgaaga
    13201 attcttttgt ccgctcttct ttaggggtgt ggataatctc atccggagtt ccagactcga
    13261 tgattttccc cttatctaag aagagaattt tatccgcaac ttgggctaca aaggacatgt
    13321 catgactgac caaaatcatg gtctgacctg acttagcagc atctgcaata gacttttcta
    13381 cttcaccgac caattctggg tcaagggctg aagttggttc gtctaagagc aaaacatctg
    13441 gtttcatagc aagcgcacgc gctagggcaa cccgttgctt ctgtccacct gataaatggc
    13501 gaggataatg gttttcacgg tccgaaagcc caaccttagc caactcttcc ttggcaatct
    13561 tagtcgcttc ttggtcagat aatttcttga caacaaccaa gccttctttc acattatcaa
    13621 gtgctgttcg acgttcaaat aaattaaact gttggaaaac catagacaac ttacggcgta
    13681 gggcaaggat ttcttcttga gtgattttag aaaaatcaac tgaaaaacca tcaatctgaa
    13741 tagagccact gtcaggtgtt tcaagataat tgagactgcg aagaaaggtt gattttccag
    13801 ctcctgaaga accaatcaag gctacaactt cccctttttg aatatccaag ttcagatgat
    13861 ccaagacagt ctgtcctgaa aaggatttgc ttaaattcga aatcttaatc attaacgaag
    13921 gtctcctttc acatctgttt gcactgtatc aggtgcagaa atagccattt ttctctcgat
    13981 gaaacgaccg aggctttcaa ttccgatatt gactacccaa taaacaaggg caacagagat
    14041 gaagcgttca aaatagcgat aatcagctcc acctagaatc tgagcttggg caaagacttc
    14101 cacaacaccc gcactaaaag ctagagatgt tcccttggtc aaaccgatga gggaattaat
    14161 caaggttgga gtagctacca ccgctgcatt aggaataatc actcgtcgat aaacttgcgc
    14221 tcgggtcata cccagactgc gcgccgcctc aatctcacca ggattaactg agagaatggc
    14281 tgcacgaatg gtttcactag cataagctgc ctcattaaag gcaaaagcga caatcgcaaa
    14341 agctgcagct ggaatcgcat tgatattgag accagttccc cattgctgat tgagggcttt
    14401 caaagccaaa ggaattccgt agtaggtcaa catgagttgc accaaaatcg gtgtcccttt
    14461 taagaaacta acaaagaagg cctgcaaggg atataaaatc ttgacacgat tgatcttcac
    14521 aatggcaaaa agaagcgcca aaaccaagcc aaaaagggca ccaccaattg tcaacataat
    14581 tgttgttgga agttgttgga caattctagg gattccatca aagaccgaac gtaggctaaa
    14641 cagcttgcca tccggaatca attgcatcaa gttttggtac caatctgatg ctaaaatcgt
    14701 tgtaacattc ataaaaacat cctcttctga taatgattca ttctaccatg cttctgccgt
    14761 caatgaaatt atttgctacg gtcagataca gactttgtct acctactagt ttatcatact
    14821 ttgaaacagg gaagttatat attttatcta tcaaagagat agataaaaac tatttcagtc
    14881 ccagttcttc ataagatttt cgataaccga tttgcttaac agttccattt tctactaaaa
    14941 tgggccgttt taacaacata ccgtcacttg ctagcaactc agccgcttct tggtttgaca
    15001 aacttcctac cttatctttt agccctaatt cacggtattt gataccactg gtgttgaaaa
    15061 attgcttcaa ttcaaatcct gaggtttcta gccaattcaa aatgacttct tggctaggtg
    15121 tttcttccac gatatggacg gctttatagt ccacacctaa ttgatttaat tcttgttttg
    15181 cttttttaca agttgaacat ttggggtatt cgataaattc taacatgtgc ttctccttct
    15241 atttgtttat atctttaaaa tctacgcctt catgctccaa gagccaagct ttcttttcca
    15301 ctcctgcagc atagcctgtc agacgcttgc ctgctcccaa cacacgatga caaggtacta
    15361 ggatagacca aggattgcgt cccactgctc caccaattgc ttgagcagaa gccacttgca
    15421 ggtcttgagc aatttgtcca taggtcactg tctgaccata aggaatgccc tgtaaatagt
    15481 cccaaactct cttttcaaaa ttcgttccga ttggcgccaa gagcaagttg gataaatcct
    15541 gaggcttgcc tttaaagtaa tcatctaagc aagcaataac tgggtctaaa ataggatgac
    15601 taacaacttc ttctatcgtt tcatctccta gtcccctctc aaaatgcttc tgctcctgaa
    15661 cccaaattcc atacaaataa tggtcatcag ctacaagtga tagaatacca attggtgagg
    15721 agtagaggat ttttacatac ttcttttgca ttatttcttt aatttttgat aggccaagcg
    15781 ttcgccatct actggcacct taccaacttg tttaaaacca agtttttcaa aaatatgttg
    15841 cataaccttg ttttcagcat gcgtatctga gcgaaaatca agataatcaa aaccttcaat
    15901 caagccctct aagaaggttt gagcaactcc ttttccctgc acatctgctg ccacagcaat
    15961 acggtgaaag actagatact ctgactctcc agcttgccag tttccctcat aaatagcttc
    16021 ataggcctcc tctggactct tggtcacagc agcataggct agcagttctc cctcttccaa
    16081 ggctacgtag gcttgccctg agatgatatc atcgataata acatctgcat ttggatagcc
    16141 attttgccac tggttactac cagcatctgc taaacatttt ttggcatcct ctatcacctg
    16201 catgatggca tctacttcat ttggaaaagc taaacgaatt tccatctttt ttcctcattt
    16261 ctgactagtt tctcccatca tagcataatt taagtctttc tacaagcagt taaaacttga
    16321 ctttgtattt ttgttatttt ataatctagt tatcaaaact atataaaaag gagttgaaaa
    16381 tgaaaactac cttttcctac ccaaaatggg cagaaattcc aaacattaac ctctatctgg
    16441 accaggtttt gctctatgtc aatcaggtct gcgcccctat ctctcctaat aaagacaaag
    16501 gcctaacagc atctatggtc aacaattatg tgaaaaatgg ttacctgaca aagcctgaca
    16561 aaaaaaaata ccaacgccaa cagattgccc gtttgattgc tatcacaacc ctcaagtctg
    16621 tattttctat tcaagaaata gcccagacac ttaatactct acaaactcaa gcaagttcag
    16681 accaactcta cgatgctttt gtggactaca tgaaccaagg aattgaccca gctaacccta
    16741 ttatccaaac cagctgccaa accgttaaac tctatcatca aactctagac ttaatcgatc
    16801 atactcaaga ggaggtaatc caatgaacac tagtcttaaa ctcagcaaac aactcagttt
    16861 tggagaggag attgctaata gcgtgaccca tgctgtgggt gcagtcatca tgcttatctt
    16921 gctgcctatt tcatccatct atagttatga agcacacgga tttttatcct ctatcggcgt
    16981 ttccattttc gtcatcagtc tctttctcat gttcctatca tccaccattt atcactctat
    17041 ggcctatggt tcgacccaca aatatgtttt gcgaatcatt gaccattcta tgatttacgt
    17101 tgccattgcc ggctcataca cgcccgttgt cttgaccttg atgaataact ggtttggcta
    17161 tctgattatt gtcatccaat ggggaacgac catctttggt attctctata aaatctttgc
    17221 taaaaaggtc aatgagaaat ttagccttgc tctttacctg attatgggct ggttggttct
    17281 ggctatcatt cctgccatta tcagtcaaac gacacccgtt ttctggagtc tcatggtaac
    17341 tggcgggctc tgttatacag ttggagctgg attttatgcc aagaaaaaac cttatttcca
    17401 catgatttgg catctcttta tcctagctgc gtccgcactt caatacatcg ctattgttta
    17461 ttacatgtaa aaaagttgag aaattcaatc tcaacttttt tctttacaca tattgataaa
    17521 gtactggtgc aagcgcacat catcagtcaa ttctggatga aaagaactta ccaacatatt
    17581 tttttcttgg gctgcaacaa tttgattgtt cactgttgct aaaatttcta caccctcacc
    17641 aacactactg ataatcggac cacggataaa ggtcattgga atcttgccaa ctcccttaca
    17701 ttctgcttcc gtgtagaaac ttcctaattg gcgcccataa gcattacgct cgaccaccat
    17761 atccatagtt cctagatgac tctctttctg agaagtgatt tccttagcca gcaaaattaa
    17821 gcccgcacag gtcccaaaca ctggtaagcc agatagaatg gcttctcgga tgggaagtag
    17881 catgttctgg tcacgtaaga gcttgcccat ggttgtagac tcaccaccag gcaaaatcaa
    17941 acccgacaag tcactctgat cttgctgaaa atcatctaga tttctgagtt ctacactctc
    18001 gacacctaat tgatctagca cttttgcatg ttctgcaaag gccccttgca aggccaatat
    18061 tccgattttc atctattttc ctcgttcagc catgagaatt tggatttcat tttcattaat
    18121 accaaccatg gcttctccta aatcttcaga gatttgagct aggatttgag gattacggaa
    18181 gttagtcaca gccttaacaa tggcactcgc tcgtttaaca ggatctcctg acttgaaaat
    18241 acctgaaccg acaaagaccc cctctgcccc taattgcatc attaacgcag catctgctgg
    18301 cgttgcaaca cctccagcag cgaaatttac aactggcaat tttccatgtt catgaacata
    18361 ttggaccaat tctacaggga cttgcaaatc cttggcagca acataaagct cgtcctcacg
    18421 taagttttga atgcggcgaa tttcctgatt catcatacgc atatgacgaa cagcttggac
    18481 tatatcccct gtccctggtt ctcctttggt acgaatcatg gaagcacctt cagcgatacg
    18541 acgcaaggct tcacccaaat ccttagcacc acagacaaaa ggaacttgga attctttctt
    18601 gtccacatgg aaacggtcat cagctggaga tagaacttca ctctcgtcga tataatcaat
    18661 ttcaatagcc tctaaaatct gagcttcaac aaaatgcccg attctgacct tagccattac
    18721 tggaatacta accgcttctt ggatttcctt aatcatcttt gggtcgctca tgcgggaaac
    18781 tcctccagct gcacgaatat cagccggaat tcgttccaag gccatcacag ctgccgcacc
    18841 agcagcttct gcgatacgag cctgttcagg attctgcaca tccataataa caccaccctt
    18901 gagcatctgt gccaagtttt tatttagttc ataacgattt tcagtcattt gttttatcct
    18961 catcatttgt attggtagct accttttcat tttaagtcag aacagaatga agcacaagat
    19021 aaaaaaacta taattgtatg gggacagatt agctaaaaac tatctgacct taacttaagg
    19081 ccagatagct cattcatttt tatttttcag ccgtaagggc agccattgtg atgtagttgt
    19141 atggtttgtt gaagtgtggc aagaagaaga ggtctgtcaa tgccaattta tcaattgtca
    19201 catgctcttg gatagcaagt gagaacatgt ggattcccat gctaattgca atatcatgtg
    19261 aaaccatttg ggcaccaaga atttcacggc tatctttgtc aaagacaatc ttaattgcta
    19321 cttcatggtt gtcatgtttc atgaattctg gtttttgaag atcgttaaag cctgtttcag
    19381 ttgcgttgta accagcagct ttcgcttttt caagagtcaa accagttgaa accatgtgaa
    19441 gaccgtagat tgagatacca tttgaacctt gaacaccgat tccttccaat tcatgtccac
    19501 aagcattgta ggcaccaacg ataccagtgc gaacagcatt tgaagcaaga gcgatatagc
    19561 ttgtatcttt acgagcattg tcataaacag tcgcacagtc accaacagcg taaacgcctg
    19621 ggatagatgt ttcttgtttc ttgtctacaa ggaaggcacc gttgcggaag agttcgatct
    19681 taccatctgc aagggctgtg tttggacgga aaccaactgc aaggataacc atatccacgt
    19741 caaagctttc tttgtcagta atcaagcgtt caactttacc gtcaccttcg attgctttaa
    19801 cagtttgacc tagagccaag cggatgttgt gatcttccaa gttcttcgcc atcatttgtg
    19861 tgaagtcttt gtcatagtaa ccgttcaaga cagtatcaac gatatcaaca aggacaactt
    19921 cttttccaag acgttcaaag gcttcagcaa gttcaacacc gatgtaacca ccaccaacaa
    19981 cggcgatacg gtcgaggtgt tggctcttgt cagaaagttt attgataact tcttcagcat
    20041 tttggtacaa tttcacgaat tgtacgtttt caagagttgc tttaaattcg cggtttcctt
    20101 taacaatttc aacaccttcg attggtggca agattggtgt agaacctgta gcgaaaatca
    20161 atttttcgta tgattctttg tgctcttttc cttcaacttc cgctgtaact actttgttat
    20221 catagtcgat tgaaagaaca ggtgagttca tgtaaacttt agcaccttta gcttccaatt
    20281 tttctttatc agaatagaac aagccttcag caccgtcaat ttgttcacca atccaaagag
    20341 ccattccaca tcctaggaaa gagatgttag agttttggtc aaatacaaca atttcgttct
    20401 catttccaaa attatccaac atggtattga tacatgctgt accagcgtgg ttagcaccga
    20461 ctacaacgat tttactcata aaaatttcct gccttcattc taaatttacc ttactagtat
    20521 accatttacc gttagcgttt acaagggggg tactattatt tcagcatttt ttatcaaaaa
    20581 taattcccca tttatcctgt tttcaagcct catgaatttt atgagcatat ttcttgactt
    20641 tttccaaatt ttgtttgtga aaattctaac tttatggtat tataataaca tgaaaatgaa
    20701 atgtaagggc ttcaatttag atgattattt gatattacaa cttattttct ataagagaaa
    20761 ggagttggta gcttgactct tcgttcacat tctgaacggc taatggggac tactatcact
    20821 atttcattag tggatgagca agccgatatc tttctccaaa aatcctttga cttgctcaaa
    20881 gaacttgaat accgcttcaa cgccaatagt caagaatctg agttgatgga aatcaattat
    20941 caagcaggaa tagcccccgt cacggttcat ccagacctgt ttgagctgat ttcacttggg
    21001 ttagagcata gcctagcgct ctctagccac ctcaatatca gcattggtcc cttaattcaa
    21061 acctggcgta tcggtttttc agatgccaag gtcgcccagc ctcaagaaat tgaatcggtg
    21121 ctgcctctaa tcaatcctca tggtatcgag ttagattctt ctacttctac tgtgttttta
    21181 aaacagaaag gaatgaagat cgatctaggt tgtttagcca aaggatacag tgcggataag
    21241 gttgcccaat ttcttaggaa agagggggtg acttctgcct tgatcaatct gggagggaat
    21301 atcctgacca ttggaaaaaa tcaggcaaga ggggataacc catggcaaat cgggattcaa
    21361 gacccagcca atcctagggg aaatcattta atgaccatcc ctgttgtcaa taaatctgtc
    21421 gtgacttcag gcatttatga acgtcacctg accgtcgatg gacaagatta ccatcacatt
    21481 tttgacagtc aaacaggata tcctgttgaa acggaactag cgagtctaac aatcatctct
    21541 gataaatcag tcgatggcga aatctggacg actcgactct ttggagaaag acctgcttct
    21601 atcctctggc aagtcgaaag tttggagggc atcgaagtca tcctcatcga taaagaaggc
    21661 cacctaagct gttcttcagg aattcctact ctatagagac aactgtttca atggaatttt
    21721 aaaattgtat tatgtaaaaa gagaaaggaa atctcatgtt aaaacttatt gctattgttg
    21781 gaacaaattc aaaacgttct acaaaccgtc aattgcttca atacatgcaa aaacactttt
    21841 ctgacaaagc tgaaattgag cttgttgaaa tcaaggccat tcctgtcttc aacaaaccag
    21901 ctgacaagca agtacctgct gaaatattgg aaattgctgc taaaatcgaa gaggcagatg
    21961 gcgttattat cggtactcct gagtatgatc actctattcc agctgttttg atgagcgctc
    22021 ttgcttggtt gtcttatggt atttacccac ttttgaacaa accaatcatg attacaggtg
    22081 cttcttacgg tacgcttggt tcatctcgtg cccaattgca acttcgtcaa atcttgaatg
    22141 ctcctgaaat caaggcaaat gttcttccag atgaattctt gctctcacac tctcttcaag
    22201 catttaaccc aagtggcgac ttggttgacc ttgatgttat caagaaattg gatgccatct
    22261 ttgatgactt ccgtatcttt gtaaaaatca cagaaaaatt acgtaatgca caagaattac
    22321 ttcgcaaaga tgctgaagac tttgactggg aaaatttgta agataggaga ccaaaaagaa
    22381 tgaaatttgt tggacttgtt ggatcaaact acgatcaatc atataaccgt aagctcttgg
    22441 aatttatccg tcgctacttc aaactcaaat ttgaattaga agttcttgaa attgacgaag
    22501 ttccaatgtt taaccaagat gaaaaatggg atgaaagttt ccaattacgt tatttatata
    22561 acaaaattac tcgtgcagat ggtgttatca ttgctactcc tgagcataac cacactatct
    22621 cagcttcact caaatctgta cttgaatggc tttcatacga agttcatcca tttgaaaaca
    22681 agcctgttat gattgtgggt gcatcatact atgaccaagg aacatcacgt gctcaagttc
    22741 accttcgtaa aatccttgat gctccaggtg ttaatgccta cacgcttcca ggtaacgaat
    22801 tccttcttgg taaagctaag gaagcttttg ataacaacgg aaatatcacc aacgaaggca
    22861 ctgttaaatt ccttgaaact tgcttagata actttgttaa atacgtagga gtcgtttcga
    22921 aattgaaaaa accaaaacca atcgaatcag aagacttgga ttgtggaaaa ccaatcgcta
    22981 caaccatcac agaagttgac cctgacgatc cagaatgggt agaaaaagtt gcagcaatca
    23041 ctggtgctgt ttctggtgat acctatgtca aattggacca cggtatccta acagttaacc
    23101 aaattgatat gttcttgaaa gctatgccat ttgaattgac atacgctgac gacaacaacc
    23161 aattcctcta ctacaacaac gctcaccaag atccagacac tatgttcgct aaacgtgtac
    23221 cacctcaatc aggtagccgt atgtcgactg ttcatggttc tcttccacca gcacgtatga
    23281 agaacgtaga gtgggttatc ggaacacttc gcaacggaaa ccaagaatac gtccgtacga
    23341 tcgttccagg ttctcctgca ggtgttatca acactcacaa ctaccaagca atgtactatc
    23401 ctgatggatc atacgctggt atcaatgaaa tcgtctttaa cttccaacca tggcttgact
    23461 ggtacctaaa agagactggt caacgtttgg tgggtggtag cggaccattt gctcctgctg
    23521 ccggaggtca tggagacgcc gatgctactt ctggcgcttc tgattcaggg gatgctggag
    23581 gccacggtgg tgacgcagac gctacagccg gtgcaagtta ctaatgatag tttttaggaa
    23641 ccattatggt tcctttttta gcgaaaaaag actagcaaac acaaactgct agtctctttg
    23701 ttatcgtttc atctatcttt gttaaaagaa agagtactta tactcaatga aaatcaaaga
    23761 gcaaactagg aagctagccg caggctgtac ttaagtacgg caaggtgaag ctgacgtggt
    23821 ttgaatttga ttttcgaaga gtattattat gaatttgggt catcaagact acggccatgt
    23881 aatccttttt cacgttgtac ttggcgtagt ttttctggtg taacatcgtt tccttcttcg
    23941 tccacaattt tgattccttc aatgtggtga cgaacagcgc ggcgataacc ttcgatgtac
    24001 tcctcacgta gtttggcttg ttccactttt tcttctgatg ttaagccttc tgtttttttc
    24061 tttttagcaa gctcattgat acgagcaatt tttttcggat ccatttcttc tcctttgtaa
    24121 taagataaag tccgtttatc aaattttatt tagtgttaat ttggttaaaa caagcaaact
    24181 tagctgcttt cttggttagt tgtgacaaga ttgccaaacg attttgacgg acagcctgat
    24241 cttcagccat taccatagta ttttcaaaga aagcatcaat gactgggcta agcgcaaaga
    24301 gttgtttcaa ttgctgactt gcaggtcctg ataaaacgag tgtttctact gcttctgcca
    24361 aagctttttc ttggtcattc tcaaatagtg ctgaatcaac tgtagcaacc ccttctgcct
    24421 tctcagccag gttaaaggca cgagaaagtg attcaacaga tggtttaaaa tattcttcct
    24481 tgcttacttc tacgagagca cttgctgctt ccaacatatc tgccacaaca aagtttgaac
    24541 ctgcaagaac tgcttccttg atatcttttg gagtagagcc catcatctta tcaacacgag
    24601 ccttgataaa gtccataacc tctgctttat tttcataagt caaactgtca aatttcaatg
    24661 cataaaggct atcaatcagc tcatccatag caatgtgcca accaaaggca tccaagatac
    24721 gaaccacacc ttgagttgca cgacgaaggg cataagggtc attagaacct gatggaatca
    24781 atcctactga gaagaaactc aaaatcgtat ccaatttgtc tgcaatggct agaactgcgc
    24841 cgaccttgct ctctggaagt tctccttcag ctgatgtagg catgtagtgt tcacgaatag
    24901 cagctgccac cgctggagtt tcaccagcaa gaagggtgta tttttcaccc ataattcctt
    24961 ggagttcgtc aaattcacca accatacctg tcaataagtc aaacttgtaa atggctgctg
    25021 cacgagcaag gtcaactgtt tcatccactg acaaaccagc tttttctgcc aaaagtacag
    25081 tgatttgacc cgtacgaatc atgtgttcac gaagggaacc aatcttctca tggaaggtga
    25141 cattgtttaa tttttcaaca agatctgaaa tcaccaattt ttggtcttca cgccagaaga
    25201 attctccgtc ttccaagcgg gctaccaaga ctttttcatt tcctttaatg acatttttca
    25261 aacgctctgc gtttccgtta cgaacagaaa tgaagtttgg caagagtttt ccatcttgat
    25321 cacgaacaac aaagtaacgc tggtgttcct tcatagaagt caccaagact tcttctggaa
    25381 cttcaaggta tttagcatca aaacttccca tgaaggcagt tgggtattca accaaattca
    25441 agacttcatt cagcaaatcc gcatcaattt cgatacgtac accatgtttt gcctcaattt
    25501 ccttgatttg gtcaacaatc atttgctcac gttcacatgg atctgcgatt acaaactgct
    25561 tacgaaggtc ttcttcatag ctcaatgctg actgaatttt ggtttctttc cccaagaaac
    25621 gatggccacg gctcacacga cttcccttga tatcaaggaa atccaagtca aactcttgct
    25681 catccaagag aacagttaaa gtgtggacag gacgaatgta ttcaaagcta tttccagccc
    25741 agtgcatgct gacagggaaa gtcaatgact tcaagacatc tacaacacca ggaacaatgg
    25801 cttcaactgc ttgaccaact tcttccttag tgacatagac atattcttca cccttgattt
    25861 cacggaattc gatatcttca acagtcaagc cttttccacg gacaaatcct tgagctgctt
    25921 tggtaaagtt tccatcacta tccaaggcaa ttttctttgc tggtcccttg aaatcttctg
    25981 tcaaatcaga ctgtttgtct gataaaccag tcacacgaac agccaaacga cgtggtgttg
    26041 agaaggtttg aatggcttca aaagacaggc ggttttcctt gaggaaggct gccatttttt
    26101 cgcctagttg tttttcactt ggtgtgacaa cataggctgg taattcttca agaccgagtt
    26161 ctactaataa gttttttgtc atgttttttc ctttacattt tcttcaatct tttttgatat
    26221 gcaccttagg tactggggac gtcgctaact aactctgtga gtctgtatgg aaatccaatg
    26281 ctaaatttat caagatttcc aacaatctca tcaaagtgga tttagctgac tgatttttga
    26341 acctaaggtt tcaaaaatcc ccacataaca gtacggcggt gcatatacct ctagcaagtc
    26401 ttcgacttgc ctctaacgat tttagagtac agtattactc actattctgc gtcttctgct
    26461 aaaagtttaa ctcgtgtttc ttcatccaaa agtgggtaac ctaggcgttt gcgttctgca
    26521 acaaaggttt tggctacaac acgggccaag ttacggatac gagcgatata gcctgcacgc
    26581 tctgttacag atacggcacc acgcgcgtca agcagattaa aggtatgtga acatttgaga
    26641 acatagtcat aggcagggtg taccaagcct tcttctaatg cacgaccagc ttctttttca
    26701 aacttatcaa agttttcaag caaaatttct tggtccgaaa tttcaaatga atattttgag
    26761 tgctcatact caggctggat aaagatttct ccgtatttta caccatcagc ccactcgata
    26821 tcatagacag agtctacttc ttgaatgtaa gaagccaagc gctccaaacc ataggtaact
    26881 tccgcagtca cagggccagt tgccaatcca ccgacttgtt ggaaataagt gaactgagtg
    26941 atttccattc cgtcaagcca aacttcccaa ccaagaccag ctgaaccagt tgatgggttt
    27001 tcccagttgt cctcaacaaa acgaatatcg tgctccaaag gattgattcc caatttttcc
    27061 aaagactcaa ggtaaagttc ttggatattt gatggagaag gcttcatgac cacctggaat
    27121 tggtggtgtt ggtagagacg gttagggttt tccccataac gaccgtcagc aggacgacgt
    27181 gatggctcta cataagctgc attccatggc tcaggtccga tagcacgaag gaaagtgtaa
    27241 ggactcattg tccccgcacc tttttcattg tcataagcct gcataagcat acaaccttgg
    27301 tcattccaaa attgttgcaa agtcaaaata atttcttgaa atgttaattt cttagacatt
    27361 gtttactcct taataaaaaa tgatttcttg cgacacgagt ct
//
LOCUS       DAVBNZ010000026        26837 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000026 DAVBNZ010000000
VERSION     DAVBNZ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26837
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.026"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(1..446)
                     /locus_tag="VQ860_001147"
                     /pseudo
     CDS             complement(1..446)
                     /locus_tag="VQ860_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(508..957)
                     /locus_tag="VQ860_001148"
     CDS             complement(508..957)
                     /locus_tag="VQ860_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3119578.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(959..1717)
                     /locus_tag="VQ860_001149"
     CDS             complement(959..1717)
                     /locus_tag="VQ860_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3119579.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLVN"
     gene            complement(1832..3811)
                     /gene="pknB"
                     /locus_tag="VQ860_001150"
     CDS             complement(1832..3811)
                     /gene="pknB"
                     /locus_tag="VQ860_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET3119580.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3808..4548)
                     /locus_tag="VQ860_001151"
     CDS             complement(3808..4548)
                     /locus_tag="VQ860_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET3119581.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(4563..5876)
                     /gene="rsmB"
                     /locus_tag="VQ860_001152"
     CDS             complement(4563..5876)
                     /gene="rsmB"
                     /locus_tag="VQ860_001152"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET3119582.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSVYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIANIKRKNKRDSIAYSLPVWLVTKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANSSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5869..6804)
                     /locus_tag="VQ860_001153"
     CDS             complement(5869..6804)
                     /locus_tag="VQ860_001153"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET3119583.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6817..9213)
                     /locus_tag="VQ860_001154"
     CDS             complement(6817..9213)
                     /locus_tag="VQ860_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET3119584.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKTMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARIFRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9279..9593)
                     /locus_tag="VQ860_001155"
     CDS             complement(9279..9593)
                     /locus_tag="VQ860_001155"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET3119585.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9618..10244)
                     /gene="gmk"
                     /locus_tag="VQ860_001156"
     CDS             complement(9618..10244)
                     /gene="gmk"
                     /locus_tag="VQ860_001156"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET3119586.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10374..11987)
                     /locus_tag="VQ860_001157"
     CDS             complement(10374..11987)
                     /locus_tag="VQ860_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET3119587.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(12330..15077)
                     /locus_tag="VQ860_001158"
     CDS             complement(12330..15077)
                     /locus_tag="VQ860_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HET3119588.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILNSVTGDEKKII
                     EFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSANNHLFNAEFTVKNLYNF
                     LKLNCLCVEHYKIYKSIINRYLEILLLSYDNSYVNPDSSIFDRTSSWLKNLDLDDVKL
                     ILPNIDFKVVNLYFRNYSFGKIKVTEEAKDYLLNRITYLQERLEITEDENLRELKNML
                     IFLPLVDDIDIEKVIEILNNQTLYYNWSEEFRRIIKIVLDNMDVIDKDSLKSKIIGIV
                     NKHLNEILEKNFSLYNSVYPLYSQLLEYCSTDQETAIIVLEKFNTDILRIKYKNDDIK
                     NIIEYSDLICHLFKYFEKDIKDDILDTLKVYEESENIIYHKVIDLMSYNVYDFPQIQN
                     KIYHYLIKRINDKRVEGVKTFPDPREKSVSDLYNLSRKGYFSDFEILKDIEEDIRGLY
                     PEVDWTWFHDRSDDVIHRLLEHRTPNNIKTYFSKNEEDNKLINEYILKAFDEDKLILK
                     K"
     gene            complement(15424..16521)
                     /locus_tag="VQ860_001159"
     CDS             complement(15424..16521)
                     /locus_tag="VQ860_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3119589.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(16531..17277)
                     /locus_tag="VQ860_001160"
     CDS             complement(16531..17277)
                     /locus_tag="VQ860_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3119590.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYEILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(17380..17733)
                     /gene="rsfS"
                     /locus_tag="VQ860_001161"
     CDS             complement(17380..17733)
                     /gene="rsfS"
                     /locus_tag="VQ860_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET3119591.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHIEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(17746..18246)
                     /locus_tag="VQ860_001162"
     CDS             complement(17746..18246)
                     /locus_tag="VQ860_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3119592.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEECFADVL
                     DYKHIF"
     gene            complement(18247..18840)
                     /gene="yqeK"
                     /locus_tag="VQ860_001163"
     CDS             complement(18247..18840)
                     /gene="yqeK"
                     /locus_tag="VQ860_001163"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET3119593.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(18840..19469)
                     /locus_tag="VQ860_001164"
     CDS             complement(18840..19469)
                     /locus_tag="VQ860_001164"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET3119594.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(19521..19832)
                     /gene="yhbY"
                     /locus_tag="VQ860_001165"
     CDS             complement(19521..19832)
                     /gene="yhbY"
                     /locus_tag="VQ860_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET3119595.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(20046..21152)
                     /gene="yqeH"
                     /locus_tag="VQ860_001166"
     CDS             complement(20046..21152)
                     /gene="yqeH"
                     /locus_tag="VQ860_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET3119596.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKFEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(21155..21745)
                     /locus_tag="VQ860_001167"
     CDS             complement(21155..21745)
                     /locus_tag="VQ860_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET3119597.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(21697..22605)
                     /locus_tag="VQ860_001168"
     CDS             complement(21697..22605)
                     /locus_tag="VQ860_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3119598.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(22662..23222)
                     /locus_tag="VQ860_001169"
     CDS             complement(22662..23222)
                     /locus_tag="VQ860_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET3119599.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            23361..24569
                     /gene="sstT"
                     /locus_tag="VQ860_001170"
                     /pseudo
     CDS             23361..24569
                     /gene="sstT"
                     /locus_tag="VQ860_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            24637..25590
                     /locus_tag="VQ860_001171"
     CDS             24637..25590
                     /locus_tag="VQ860_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3119600.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            25733..26113
                     /locus_tag="VQ860_001172"
     CDS             25733..26113
                     /locus_tag="VQ860_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3119601.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            26212..26433
                     /locus_tag="VQ860_001173"
     CDS             26212..26433
                     /locus_tag="VQ860_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3119602.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            26450..26764
                     /gene="trxA"
                     /locus_tag="VQ860_001174"
     CDS             26450..26764
                     /gene="trxA"
                     /locus_tag="VQ860_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3119603.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
BASE COUNT         7488 a         6044 c         5017 g         8288 t
ORIGIN      
        1 ttagcggctt gagtttgctg gatttacgtg gaatttgtgc ttgaggatat atcttcatga
       61 gcccttgata atcactgtca gccaagattt taccagcttg tccgatattt ctgcgactca
      121 ttttgaacaa cttcatatca tgacaatagt tcacagtgat atccaaagaa acaattctcc
      181 cttgacttgt gacaatcgct tgagccttca tagcgtggca tttcttttta ccagaataat
      241 tcgctaattc tttttttagg gcgattgatt tttacttccg tcgcatcaat cattaccgtg
      301 tcctcagaac tgagaggagt tcttgaaatc gtaaaaccac tttgaacaag agttacttca
      361 acccattggc tccgacggag taagttgctt tcgtggatac caaaatcagc cgcaatttct
      421 tcataagttc gatattctcg cacatataga aagcgttgtt aatttattta tctcattttt
      481 cagaaaattc ttttatttct gtaaaatcta cgatactcga tgtgttttta tataatgata
      541 cagtctgaga atcactgttc cgctagccat tccaatagag attaccaaag ccaacatgac
      601 aaccaaggtc gcacttgcca gtgctttatt atagtcccct gtcacaaaaa aggcagttgt
      661 tcggtaggag agataacctg gaaccagcgg tgccaaaatg gccaagataa agaccacagc
      721 aggtgtctta taaagaatac ttaaaatctg gctgacacaa gaaccaataa tggctgcaat
      781 gaaggtagct acaatgacat tggtcggttc cttgagcaag agatagatta gccagacagt
      841 catgcccaaa atccctccag gtaagagcat agaccgttgc acattgagta cgattaaaaa
      901 agtgataatg gcaagaaaac ttgctactgc ttgtaataaa aaggttgtta gtgtcatatt
      961 agttcaccaa taccaaggcg acagaagttc ctgcccctaa agcgagggta atgagcaggg
     1021 attcaaacat cttactcata ccagagttta tgtggttggt cataatatca cggaccgcat
     1081 tggtcaaggc aatacctggt acaaacggca tgaccgcacc agctataatc aaatctgccg
     1141 ttgaaggaaa acctgtgtag cgagcccaaa actgggcaat tatcccaaag acaaaggctc
     1201 cagcaaaggc tgtcacaaag ggaattcgga taaatttttc cacatagagg gaaaaggcaa
     1261 aaccaaataa ggtcgccact cctgccccaa gtgcgtcgta gatatttccg ctaaacataa
     1321 ctgaaaagaa aggagcacta aaggtcgcag ccagagttac ctgcaactta gtatagggaa
     1381 ggggttgagc ttgcaaggcc gtcaattgct taaaggctgt ttctaaatca atctgccccc
     1441 caaccagctg acgagaaatc tggttcacat cgcagacttt ttcgatgtta taagaagagg
     1501 aggtcacgcg cttcatgcgc gaaatattgg tattttcaat agagaaaaag atagcggcag
     1561 gcatggcaag gacattgcaa tccacaatcc cctgcgaatg cgcgattcga atcatggtat
     1621 cttctacacg atggatttct gagccacttt taaggagaat agtccccgct agcataatca
     1681 catcaatgac ggcatttaat tcttttgatt cttccatgct ttcctccttt tatcaactcc
     1741 ctctattcta tcacaaatct ggactcaaaa aaaatctttg ccatgaaatc atgacaaaga
     1801 ttgattactc attttgatta tccatctact tttaaggagt agctgaagtt gttttaggtt
     1861 tgtagattga aatcttgact ctagtcttat tgaggtctac cttttcacct gctctaggac
     1921 tttgttcaac aaccatgcct tctgcactac ctgcaggcgc tgtcgtcact tctacaactt
     1981 ctatattagc ttccttaatc ccaacaattt gaatcaaatt gttcttagta aactccaagc
     2041 tggaaccaat gtaactcggc atggcaacac ttgtaacttt tttagctact gtcaagacaa
     2101 tttgagtagg tttactcaca tcataagtcg ttccggcacc tggactttgt ttcataatcg
     2161 ttcctggttc gctttcgctg gactcttctt cctctatctt aatcaaattc tcaggaacct
     2221 tcttctgctt gagttctgag attacttctg tagagttccg tccaatatag ttccctaatt
     2281 gaatcgtcgt agctttttta gctactgtca aaacaatttg agttgccttg ctcaagtcat
     2341 aggtcgtacc ttctggtaga ctttgcttca ggaccgttcc agcctcactc tcattcgact
     2401 cttcttcctc aattttaatc aaattatctg gaactttttt ctcttttaat tccgcgataa
     2461 catcagaaga tttccggccg acataattac taatttggaa ggattgtttg cctgatgaga
     2521 caaccagatt gattttcgtt ccttcttttc gaccagttcc agcgccagga tctgtacgga
     2581 taatccgccc ttcttccacc ttttcactag cctctgtctt ctcctcacca atctcaaaat
     2641 tggctttttt gagcgttgcc ttggcctctg caactgtctg acctgccaca tctggaatgg
     2701 caatggttgc aggagttctg gatagtatcc aaataagaga agctgccacc aatacaaggc
     2761 tggccaacaa aatcaggtaa cgcatcttaa atctatgttt tttcggtgct tgtggttggt
     2821 aagtttcctc tgtcacagcc tggcttgggt ttttgattga tttgtgttct gtctgcgctt
     2881 gaaccttagg aatagatgtc aaggtactct gagaaacctt cggcaaggtc ttggtatctg
     2941 ccttgctcgt ttcatcaaag attaacttac tttcatttct acgattgtag gacaagctac
     3001 tagacaagtc cacatacatc tctgaaaccg agcggtagcg attggtcaac tttttagcag
     3061 ttgccttgat aataacattt tctaaagcct gaggtacaga tggattttct gcaataacgg
     3121 acggcagggg tttctggaaa tgctggaggg caatggtcac cgcgctatcc ccgtcataag
     3181 ggatatggcc tgtcaacatc tcatagaaaa taatccccat ggcatagata tcactctgca
     3241 cagtcgcctt cgaaccacgc gcctgctctg gtgacaagta atgaactgag cccaacatcg
     3301 agttagtctg ggtcagactt gtctctgcaa aggctacagc aatcccaaag tctgtgacct
     3361 tggccgtccc atctggtgtc aaaaggatat tttgaggttt caagtccctg tgaacaattc
     3421 ctcgagtatg ggccaagcgc atagccaaga gaatttgtcc catgatacgg actgcttctt
     3481 cattagaaag aggataatgt tccttgatat agcgtttgag gtctagtcca gcaacatact
     3541 ccattgcaag atactgttga ccgtcttcct caccaatatc tgttatccga acgatatgag
     3601 gatggtctag atctgccata gctctcgctt cacgctgaaa acgagctaca gctatcgggt
     3661 ccgtctggta gttggtcctc agaaccttca ctgccacttc ttccccatct aagattaagt
     3721 ctttggctag gtagacatcc gccatacctc ctcgaccaat ctgtttgaca atccgatagc
     3781 gtccggcaaa aatcttgccg atttggatca ttctgcatcc tcctcgttca tagaaacaag
     3841 ggcaaccgta atgttgtcta aacctcctgc attgttagca aaacgaacaa gtgtctccgt
     3901 tttatctgct aaaggaatat cactggttac aatatcacga atctcactgc ctgaaatcat
     3961 gttggtcaag ccgtcactat tgagcaagag atagtcacct gactcaagga taactgtccc
     4021 aaaatcaggc tgaatttcat ctttttgccc aatagactgg gtgataatat ttttttgcgg
     4081 atgagcttct gcctcttctg gtgtcaattg accagccttg agcaattcat taaccaagga
     4141 atgatcgctc gtcaactgat ggtattcttc tccacgaatc aagccgatac gcgaatcacc
     4201 aatatgagca tagatagcct gattatcaat aatagcaagg acttccaaag tagttcccat
     4261 gcctctgtaa gcttcatcct gaccaagctg gtgaatcttt tgattttcaa tttctaggta
     4321 atgggcgaac cattcacgca cttcattgac tgtatcgatc tgggtatcaa cccaagctac
     4381 acccaggtct gtgaccgcca tttcactagc gatattccct gcacgatgac ctcccatccc
     4441 atcagctaaa ataatcatgg tacgtccagc tctattgaca tagtggttga catagtcttg
     4501 gttatttgtt cgtttctgac caacatctgt taataatgaa atttccatgt gtcagttcct
     4561 tcctaatccg atatcttgcg aaattgactg atgaagaatc catcacttcc atacaattca
     4621 ggtgtaatga ggatacagcc gtctttcatg atatccttac attcatgttc tagttttacc
     4681 tgctcgaact cgggatgact ctctaaaaag gccttaacga cttgaaaatt ctcctctgag
     4741 acgatagtgc aggtgctata agttattata ccacctttgc ctagtatttg acaaacacta
     4801 cctaatattt ctaactgaat ttcctgcaag gacgcgaaat ctgccgtttc tttattgtat
     4861 ttgatatctg gttttcggcg caaaagaccg attcctgaac aaggagcatc caccaaaatc
     4921 ttatcaaagg aatcctggtc aaaaaactca tgcacctttc tggcatccaa tttttgagtt
     4981 tgaacccgat cttcaactcc cagacgttgg gcattttctt gaattaaatc caacttgtgg
     5041 tcgtacaagt ccagagcagt aacctgacct gtcgtaagat aagaggctat atgggctgtt
     5101 ttcccacctg gagccgcaca ggcatcaagc actcgctcat caccttgtaa atcaagcgtc
     5161 ggagcaacca gctgactgga ctcatcttgg atggtaatgg ctccatccgc aaacaaatta
     5221 tgccctgcaa aatgcccttg ctccttaacc agaccagtgg ttgctaaaag ggaactattc
     5281 gcctccaaca aggcttggat ttcctctttt cgacttaggt ctgttacacg aatactagct
     5341 ttgtttcgca ctaacaagct ttcaaagatg gcttttgctc tctcctctcc gtattcttcc
     5401 ttgagtttgg taactagcca aactgggaga gaataggcaa tggagtcacg cttgtttttt
     5461 cgcttgatgt tagcaatatc tggccagcct tcacgcaaga tacggcgaag gacagcgttg
     5521 accaattttt cactgccttt tttacggagt ttggccaatt ccactgcttc attgaccaca
     5581 gcatgatctg gaatcttgtc caaatagcgg agttggtaga cactcatgag aagaaggaca
     5641 tagagccagc tgtctaactg gtctctgtct tcgataaagt gggataggta ccattccaga
     5701 gtcagtttac gggctaccgt tccatagact agctcggtca ctaagccctt gtctgctgca
     5761 gagagctgac tccccttgag gtgtttattt aaggcgatat ttgaatatgc ttggttcaca
     5821 aaaacatcct ctagcactgc tagagctaaa cttctagccg tttctacttt agtcaccaaa
     5881 tcgttctcct acagtcaatg tacgtccaac tccgttgagg aaggaagcaa tgtccatctt
     5941 aggcttacca gctggctgca cttgtttgag ggatagagcc ccttcagccg ttgcgacaat
     6001 caattctttc ttgccgatag agagaatctc acctggattt ccctgacctt ctactggtag
     6061 ggcttcataa atcttaaagc ggtcgccctt aaggaaagta tgggcaacag gccaggggtt
     6121 cattccacga atttggttaa agagttgacg attggttttg ttccagtcca gtttttcttc
     6181 ctctggcttt atatttggag agaaggtaac ctgactcgta tcctgcggtt caggtttgat
     6241 atcaccagca atataggcag gcagagtgtc caaaagcaaa tcacgaccaa ctagcgccaa
     6301 tttttcaaac aaggtgccaa cattgtcctc atctgtgatc ggaatgctgc gacgagaaat
     6361 catatctcct gcatccattt ccttaaccat ttccatgatg gtcacaccag cttcctcatc
     6421 cccttgaatc aaggcataat ggataggcgc accaccacgg tgtctaggaa ggagggaggc
     6481 atgaacgttg acagcaaagt ccatgctatc aaggagtttg cttgggagaa actgcccaaa
     6541 agcagcagtc acaattccat ctgctcctag cttcataagt tcttccatct ctggacttcc
     6601 agataatttt tcaggttggt agatagatag tcctgcttcc ttggcagcct gcttgactgg
     6661 ggtttcttgg ataacttttt tacgaccaac agcacggtct ggctgggtca caacggctag
     6721 aatttcgtaa cggtcatctg tcaaaagtcc ttttaagact gttgctgaaa agtcgggggt
     6781 ccccataaag attagttttg tcatatcttc tccttcttat aaaaattgct gcggctcatg
     6841 gtcaatgctg agacggagct cactattttc ccgttcttga gtcaaggcca agacctggtt
     6901 gagggtcggc cccagctcat cttctaaacg gtatttaatt aaaatctggt aatgatagag
     6961 gttgtgggta cgggcaatcg gttttggcgt tggccccaga atgggactgg tctctgacaa
     7021 gcctgaccgc aaaatgttca tgacttcata ggcacgtttg aaaacctctt cttctttctt
     7081 gtgagaaagg gtaataccaa tcgtgaaata gtaaggtgga tagccgagtt gtcgtctgat
     7141 tcccatttca taggcataaa agccttcgta atcttgatcc ttggcaaatc gaatagcata
     7201 gtgctgcgaa ttgtaggact gtatcaagac ttgacctgct ttttcagccc gacctgctcg
     7261 acctgctacc tgagtcaaga gctggaaggt tctctcagaa gaacggaaat caggcagatt
     7321 caaggccgta tccgcattta gaactccgac tagggtaaca ttgggaaaat ccaaaccctt
     7381 tgcaatcatc tgagtaccaa gtaaaatatc cgcttcccct cgcccaaact ggtcaagcaa
     7441 ggcttggtga ctgcctttct ttcgagtcgt atccacatcc atcctaaaaa tgcgagcttg
     7501 gggaaagagt tctgctagct catcataagc cttctgagtt cccgtcccat agtaacgaat
     7561 actgtggctc ttacagttag gacagacctg aggaatatcc ttcgagaaac cacaataatg
     7621 gcagttcata gtcttggtat ccatatgcaa ggtcagagaa atatcgcagt tgggacaagt
     7681 atccaccgtc ccacactccc gacacatgac aaagctagaa taaccacggc gattgagcat
     7741 gagaaccacc tgctcttttt taaccagacg gtcttggata gcctctagca aaggaggcgt
     7801 aaagtttgac gtctcatttt gtccgatata gtctcgaaag tcaatcactt gaacctcagg
     7861 gattgtagcc aaaggattgg cacgttgggt tagacgtaag tgttgataga cgcctttgcc
     7921 agcacgtgcc cggctctcta agctcggcgt tgcagatcca agtaccagag ttgcttgatt
     7981 atactgagcc cgtaaaatag ctacctctct ggcatggtaa cggggattgc tgtcctgctt
     8041 ataagccgct tcatgctctt catcaataat catgacaccc agatttttca gaggagcaaa
     8101 gatagcagat ctggcaccaa caacaacttg ggcatcgcca cgctccacct tgcgccattc
     8161 atcatacttt tcaccattgg ataatcctga gtgaagaatg gctaccttgt ccccaaaacg
     8221 tgctataaaa cgctcggtca tctgaggagt caaggaaatc tcaggtacca gcaaaatagc
     8281 tgtcttgccc ttatccaggg caccttggat aatctgcaag taaacctcgg tcttcccact
     8341 tcctgtaatc ccttgaagta gaaagggagg ttgagaactg ccaatagaac tcacaaccgc
     8401 atcacgcgcc tgtctttgtt ctggatttaa ctccaaaggt ctacttgctt caattccttc
     8461 aaaataagca gccgagcgtt gaacttcctt ttggactatg gtaacagcac cttgatccac
     8521 aaagaagttg acttgctctc gcgagtagga ctctaacaag ctagccaagg aagcgctctc
     8581 tggatgagac agcagataat ctctcagttc caactttttc ttggcacgtg tagaaatctc
     8641 aacaccttct aattgggcat ggtcaacctc ataccaagac tgggtcttga ccttcttttg
     8701 atcgactgcc tgatattcca gaccaagcag gccttttcta gtcaaacgca tcatttcagc
     8761 ttgcttggca aggtctagtg aagaaaaggc tagcgaatct tctgaaccaa acaggcgtac
     8821 tcgttcttcc tgactcaagc cttccagagg atagagaatc ttgtcatagc tagaattcag
     8881 aaatcctgga agcatggtct tgaggataga gattttgtag gagaagacag atttgcgtaa
     8941 ctcctcagcc agccagagtt gttctggcgt gagaacagga gaaaaatcca gcacctctgc
     9001 aatatctttt aaatcttgct ccatctcttc tccatctgat tgggactcca aaccaagaac
     9061 aatcccttga atcaggcgat tacccttacc aaaaggtaca tgaacccgca tcccaacttc
     9121 cagcattccc tcaaattcct ccggaatcct gtaactatag ggctggtccg tctgcatcaa
     9181 aggcacatct acgataatct tagctagggc catcttctca cctcctcctt gtcagtacat
     9241 tcttgcaata gaaaaaataa gattgagtcc ccccaacctt aaattttttc accatcttct
     9301 ttttctttag caatttgctc tttgattttc ttttcttctt cttctttgcg gcgtttctct
     9361 tcttcgatac ggcgacgcac tgcttcacgt tttccttctg gatctgggtg aattgtaacg
     9421 tttcctgatt cgatttcttc taaagcgcga agagttgatt tttcagactt gaaaccttga
     9481 gttgctgggg cacctgcttc caattcgtgg gcacgttttg cttccaagat tacgagtgaa
     9541 tattttgaag gaaccttgtc gagcaaggta tcaatagagg gttttaacat catttgcttg
     9601 tacctatttt ctaaatttta tcgggtagtt ggagattttg gtaacatctc ctgatagtga
     9661 ccaatgacac gatccacaca gaagtgttct gcttcaatca cacatttgac acgttcagca
     9721 gctaggggca cctgatcgtt gacaatcgca taatcatact cacgcatgag ggcaatttct
     9781 tccttggcct tttcgattcg ttgggcaatc acttctgcac tatctgttcc acgacctacc
     9841 aagcgatctt gcaattcatc caaatctggt ggtgtcagga agataaagac agcatctgga
     9901 acctttttct tgacctgaag agcaccctga acttcaattt caaggaaaac atcgattccc
     9961 ttgtccaagg tttcattgac ataggtcaga ggagttccat agtagttgcc gacatattct
    10021 gcgtattcca acatctgtcc ttgacgaatc agctcttcaa attcttcacg agtacggaag
    10081 aaatagtcaa caccgtccac ttctccagga cgttgtgcgc gtgtcgtcat cgatacagaa
    10141 tattgaaatt ggttttcaga actctcaaaa atctctcttc taaccgttcc ttttccaacc
    10201 cctgaaggac cagaaaaaac gattagtaag cctcggtctg ccattgtgtc tccttttagt
    10261 caatctgtga aataacattt ctctagaata atggcaaaaa gccagattat cctttacagt
    10321 ctttctatct agtgtaacaa aaaagcagta atttttcaac tgctctttct tatttattta
    10381 gcataatcta ctgcacgaag ctcgcgaatc acggttacct tgatatttcc tggataatcg
    10441 agattgtttt caattttctt acgaactttg tgagccaaga ttgtgacttt gtcgtccttg
    10501 atttttcctg gattgaccat gatacgaatt tcacgtcctg cttgaagggc aaagctagtt
    10561 tgcactcctt caaagccgtt agcaatttct tccaaatcat ggagacgctt gatgtagctt
    10621 tcaagagact cactacgagc acctggacgg gctgcgctca aggcatctgc tgcagcgacg
    10681 ataactgcta tcacgctctc agcttcaaca tctccgtggt gactagcaat cgtattcacc
    10741 acaactgggg gttccttgta cttacgggcc aattccatac cgatttcaac gtggctacct
    10801 tcaacctcat ggtcaatggc tttcccgata tcgtgaagga atccagcacg acgggcaaga
    10861 gccgcatttt caccaagttc gctcgccatg ataccagcca acttagcaac ctcaatcgaa
    10921 tggcgcaaaa cattttgtcc atatgaagta cggaactgca aacgtcccat aatcttcatc
    10981 aagtctggat gaaggtttgg cgcaccaatt tcataggcag cagcctcacc gtattcacga
    11041 atcttattgt caatctcttg acggtttttc tcaaccaact cttcgatacg agctggatgt
    11101 atacgaccat ctttgagcaa catttccata gtcatacggg caatctcacg acgaatcgga
    11161 tcaaatcctg acaaggtcac cacttctggt gtatcgtcga taatcacatc gacccctgtc
    11221 aaactttcaa aggtacgaat gttacgacct tcacgaccaa taatgcgtcc cttcatagta
    11281 tcgtctggca gatgaactgt tgagtttgtt gactccgcta catattcacc agcgatacgt
    11341 tgcatagctt gaaccaagat atccttggcc attttgtcag aacgttcctt gacctcttgc
    11401 tcagcttcgc gaatgcgact ggcaatctcc ctggtcaagt tttcctctgt ctgagccaag
    11461 ataatatctc gtgcttctgc ctgagacaga gcaccaatac gctctagttc tgcttctttt
    11521 tgtctttcga cttcctctaa ttgctcttca cgcgcatcaa ggtttttcgc tctatcagaa
    11581 atactttgtt ctttttgttc aagtgtttgt tctttactcg tcaaattgtc gtccttacgg
    11641 tcaaggctag tagctctctc tgtcaaacga ctttcgattt gtttgagttc ttgacgttct
    11701 gatttgaatt cagcgtccac ttcttcacgg tattttctgg cttcttcttt ggcctccaat
    11761 agtgcttctt ttttaagaga cttgctttca cgtttagctt cattaacaag taaatccgct
    11821 tcacgctcag cttgtccacg taaattagtt gcttcttgtt cagcatttaa aagcatcaac
    11881 tccgcagctt cctgagatga tttcatctta gctgagatgc tgacatatcc aatgactaaa
    11941 ccaatgatga cggcaaaaac agcaatcgca agcgacatga tctccatgtt tttacctcat
    12001 tttattgtta ttccgaatga catacattct tttacattct accataaaaa agtgattttc
    12061 acaaacctaa aatagaatat gttttgggga aattagtctg aattttagga ttacacttcc
    12121 ttggtttttt aaggagataa gtcagtgccg ctatcaaaaa gttccaccga atttctaccg
    12181 ctatggattt tctattgttg tgccaaatag tgttccacta gattcaaaca ttttgctttc
    12241 aagtctttga aaattcactt taggaaatca cagcttatct tcaagatcaa atttgtcata
    12301 aattaacttt tttatttagt tgtatcaatt tatttcttaa gtattaattt atcctcatcg
    12361 aaagctttta aaatatactc attaatcaat ttattatctt cttcattttt tgaaaaataa
    12421 gttttaatat tattgggagt tctatgttct agtagacgat ggataacatc atcacttcta
    12481 tcatggaacc aggtccaatc tacttcagga taaagtcctc gaatatcttc ttcaatatct
    12541 tttaaaatct caaaatcaga aaaatatcct tttctactta agttgtataa atctgataca
    12601 gacttttctc ttgggtctgg gaaagtttta accccctcaa ctcttttatc attaattctt
    12661 ttaatcaaat aatggtagat tttattttgt atctgaggaa aatcatagac attataactc
    12721 atcaaatcaa ttactttatg gtaaataata ttttctgatt cttcataaac ttttagagta
    12781 tctaaaatgt catctttaat atccttttca aaatacttaa ataagtgaca tatcaagtca
    12841 gaatattcta tgatattttt tatatcatca tttttatatt ttattcttaa aatatctgta
    12901 ttaaattttt cgagtactat tattgcagtt tcctgatcag ttgagcagta ttctagtaac
    12961 tgtgaataga gcggatacac tgaattatat aaagaaaaat ttttctccaa aatttcattt
    13021 aaatgtttat ttacaatccc aattatctta gatttcaatg aatctttatc aataacatcc
    13081 atattatcga ggacaatttt aataattctc ctaaattcct cgctccaatt ataatacagt
    13141 gtttgattat ttaaaatttc tattactttt tctatgtcaa tatcatcaac aaggggaaga
    13201 aaaattagca tatttttaag ctctcgaaga ttttcatctt cagtaatttc aagtctttct
    13261 tgaagataag taattcgatt caacaagtag tctttcgctt cctcagtaac ttttatttta
    13321 ccaaatgaat agtttctaaa atataaattt acaaccttaa aatctatatt cggaagaatt
    13381 aatttaacat catccaaatc aagattttta agccaagaag atgttctatc gaaaatactt
    13441 gagtcagggt ttacatatga attatcataa ctgagtaata atatttctaa atatctatta
    13501 atgattgatt tataaatctt ataatgttca acacataaac aatttaattt taaaaagtta
    13561 taaagatttt ttactgtaaa ctccgcatta aatagatgat tattagcaga ccatcctcct
    13621 cttctatagc tttcatgctc ttcacgaatt tcatcaaata attcattaat agtttctaat
    13681 tttctatata aaaaattgaa gttaaggatt gaatctctaa aaaattctat aatctttttc
    13741 tcatctcctg taaccgagtt aagaatttgt tctgttaatt cgcttaattc tccatcataa
    13801 agtggctctg cataactagg tgttttttcg tatctatcaa ttatttgaat ttgctgaaaa
    13861 ttaaattcac aaactaagaa attaaaatag tctttctgac gaaatgctat attagctagt
    13921 tctctaaatt ttgcttttgc taaagaatat tgtttttctt catacaactt aaaagcctta
    13981 cttaagaatc gattcccctt taaatcccta ggctcaccaa tctccatatc tagaaagcga
    14041 tttaataaag attttttaga taccataatt cgtaattctt catgaccatc aatttcaaat
    14101 cttaattgat catttccaaa ccagcaatac tcatcatccc agtttaaagc ccttttcttt
    14161 aaatcagaat atctagaaaa atctttcgca tcaataaaac taagtctatc taaaaaagcc
    14221 agttgattcc ataaatcatc agcattattt acatcttgac ttcggttttc tgatagaacc
    14281 tctaaaaaat cttttgtcct gcaatacaat ttgttctgtt tttctgatgt ctcctgacct
    14341 agattctctt cattagagat aatgaaaatt ccttgcttct tataatactc tcgaatgatc
    14401 atagacggtt cctcgggagt ataaaaataa gcatttttag catccaattt aaatgtattt
    14461 tgaatcattc taaaaattga attaaaagtc gaatcactta gagaataccc cacaaacaat
    14521 agagtatgat tcattatcaa tgactggatt aaagtagaaa tcattgggaa gttcaaatga
    14581 tagtctaaat aatcatcttc tttcaaaaca atatttttct tactgaagtc accatgcatt
    14641 ttaatcaagt atctttccga actcgtataa gggatgtctt tatcctcagc gactacattg
    14701 tactttaaca agccactttc aaattgactc tccagaagtg aatcatagtt tgtcgtaata
    14761 atatgttttg gtgcaatttt ttctattaat ttatgtaact catttggttt actcaatccc
    14821 ttcttaaaga aaatttcttc tatcttcttt gtgtactgat ttttcccaaa agtatcataa
    14881 taatactgag caattctcag tggactatct gttctttctt ctggtatgtt caattctttt
    14941 tttaatgatt gaatcaattc tccccaagtt ggtagattag aattagctga tattcctgca
    15001 ccaacaaaca aaactaagga attttcttta atagaattct ttatttgagt tatagataaa
    15061 ttataatttt cttccatatt ttaactatcc tacattagct tgtactacat aaatacaaat
    15121 tatccttata aatcttcttt tttattacat aatcttaaac aaaagtttat catggtttat
    15181 aaatataaaa atttatttgt cttttatatt caatttatga ttattaatat aaccagttct
    15241 cttcattata ccacaaaata acaagcataa agcggattca gagataaaga ttaaggttca
    15301 tatactaatt ttctttattg actttttgtc ttctgtatta gggagtttat cattttccaa
    15361 aaactttatc ttcaatttgt tatctaaaat ttctacaata aaaaagccta cctttcagta
    15421 gacttagttt gtttctattc taatcggcac tctgccaaaa ttttgctctg ctatacttgg
    15481 ctttcctagt tggtaaatct ggtcaacctt ttgagtcata gcatcccaag gttctttgcc
    15541 aattcggctg actagattga cctgtccttt cagagacttg agatgttgcc tgcctttttc
    15601 agtaaatcca aggacatgaa tggcttctgg caagacattt tctctagcct gtaccaaaat
    15661 ataggtcaat aggcgtctga cacgcgcctt ggtgtaacgt ttggtagtca ctaactcgac
    15721 caattcttcc acagactggg ctgttttaat agcttcttta atgcgcacag ccatttcttg
    15781 attgacctga tagatggtgg ttaggtcggg atttgacaag atttgatagc ggagcaaggg
    15841 aaaatagtct tcccagatca ccttactggc ctgctcaaat agggcaacag aaggcataaa
    15901 acgttctaag aaatcttggt ccttctgatg ttgacggagg gctgtcgccg aggcaaagtc
    15961 cacatcttta ttcacagaat ggtaacctgc cccctgacgc tgaatcggat gcagcttgat
    16021 atttcgtcct gcaaccgcct ttgcataggc cagagcaaga acatgattgg gggtattacc
    16081 tgaaaaatca agaccagcaa attccttcca catagcttgg gttttctggg gataggaaag
    16141 ggaatcaggc agatttttca caaatttctc catctcagca cctttctctg tgtataagtc
    16201 agcgattttc tggtaatcca gaacttcctc tgtcccaaaa actagactat caatgcccaa
    16261 gcgatccaag atatccacag ctccttgacc aaagaaatca gctgcctgaa cactgactaa
    16321 aaagggcaat tccactacca agtctgcgcc attttccagc gccatctggg cccttgtcca
    16381 cttatccaca atagcaggct ctccacgctg catgaaattc cctgacatgg caacaatttt
    16441 cagtccctct gcctgatcca gcaggtattt atggccatta tgaaaaggat tgaactccgc
    16501 gataatacct gttatggtca tgctaatctc ctacttctgc gccacaaaaa accaacgggt
    16561 gctagtttct gttggctcct tatcctcaaa gtctgcatag agtttgaagg acttgaatcc
    16621 agcctgttcc agcaagatct cataggtcaa gatctcatag gtcctctcct catgtacttc
    16681 atcgtggcga ctaaaggaac catcagcctc cttgataaag aaagtcagct catggacgat
    16741 ggagtgagga acttcgtcct catatgtatc ccaaagcatg gcaaaatctt ccgcattttc
    16801 atggtaggaa tagccaggga atacttcatc tgtctggtag gtcgagtgca cgtcaaagat
    16861 gaaaactccc tcttcattca gcgcattgta cacgtcctta aagacgtccc ctacttccac
    16921 ctcatcctgc atatagcaga tagagtccga ataacacgtg acaaaatcgt atttccctgc
    16981 cttggacaaa ttcagcatat taccttctat aaaagcaatc ttttgcttgg ctgaagttgc
    17041 tctcttctcc gcaatcttca acatatccgc actcaagtca agtccagtca catcaaaacc
    17101 agcctgagag aagcgcactg attgaattcc tgtcccacaa gccaattcca agagtttctt
    17161 tctctccttg gtcttaggca aatgacgcag agaaaaattc gtccatttgt cgtataaact
    17221 atcgtccatg accgcatcat agaccgccgc aaaggtttca taagtcgcca taatcatgat
    17281 actaagagct ccatggtaaa caccactagc cctttacctt tctatcaatt tttctaaaat
    17341 aagcaaagaa acccagttga ctacaactga gttcatcttc taagcaagag cttctgaaat
    17401 atctactgaa ttcgcctcat gccatagctt ctctagatta taatgggcac gcatttcttc
    17461 tgaaaagata tgcacgacaa cagcaccgag gtccagtaag acccagcctc cagctgcatc
    17521 gccttcgata tggctacctt taaagcctgc ttgagctact ttttcacgga tattagctgc
    17581 gatagcgtcc aactgacggc tattcattga gctagtgatg acaaagtagt ccgtcacact
    17641 agtcaaatct tgtacatcaa gtgcgaggat atcctccgca cgtttctcat cagccgcttt
    17701 cacgactagt tctagtaatt ctttttcgtt catttaatcc tctttttaga aaatatgttt
    17761 gtaatctaga acatctgcaa agcactcctc ccaaatgtcc tcataaaatt cattaatcgt
    17821 ttctgctgga atgtcatccc catcaaaggt tgtgacagca ccttctggaa caataagctg
    17881 atagccatat tcaaaggcaa ccttgacaga ggtatccaca caatattctg tctgcatacc
    17941 acataaaact aatttttcaa tcccctgttt atccaagtat tcttttaagc cagtttcttt
    18001 gaaaatactg ttatacttct tctgaaagac cttttcagca ggttttcgat ttaaaagcgc
    18061 agataactgc caatcttctg atgtttgagc ttcagaattc tcaatatgtt gaacatagat
    18121 aatttcaata ttcttgcttc tagcctggtt ttgtaaataa gaaatttttt ccaatagact
    18181 ttttgtctgg aacccagttt ctactaaaac attctgaaca tcaatgatta taaaagccgt
    18241 cttcatttag tcctctttca aatagtgcac aaaggcgtta taggtttcaa gggtttgggg
    18301 atagatgggg aatccctgat gagctagata ctccacggta cgagctgttt cgtaggccac
    18361 cgccttattg agcgatagac ttgcaatctc acgcgccaca tctactccag gaaaggctcg
    18421 attgtgctcg atatagtctg cgacgtagat gaccttatct aggtctgtca tttgaccagc
    18481 accgactgta tggacttcaa tggctcgcag gatttctgaa tcatgcaaat ccaaatcttc
    18541 ctgaattttg taaattccga ccataccatg ccagacatta ttaccccagt ttttgaggtc
    18601 gaaatctagc tgataacggt caatcaagtc tagaaattcc tgatctgaca actttttagc
    18661 atagtcatga agaagacctg ctagacttgc tttctcaaca tctacaccaa agcgctgagc
    18721 taactccata gcggcacgct ccacacctag acaatgggtt agacgtttct caggtagaag
    18781 ctctgccatt ttttccaaca aggcctcacg ggagcagttg atatagtctt gataggacat
    18841 cagtagagcc cctccttctc gatgtagtct agcactggct gaggtaggag aaagttgggt
    18901 ttccgacctt gggcaatgaa gtcccgcacc atgctggacg agatatccat gagcggtacg
    18961 tccacccaga taactggata ggaagtccct gccttgtagc gtggacgctg aacccccaca
    19021 aactgaacca tgtcaaccag ttcatcaatt cggtaccact taggcagata gtcaaccatg
    19081 tcggcaccga tgataaagta ataatccgta tctggatgtt gctctgtcaa gattttcatg
    19141 gtgtcgtagg tgtaggaaat acccttgcgc tccaactcaa tggtttcaat gactaggccg
    19201 tcaatcccct caattgccaa ctcaagcatc ttgagacgat ggtgttcagg gatggtttcc
    19261 tttttatcaa cgtgaggagg ttggtattca ggcatgagaa gaacttgatc cagtcccaac
    19321 tgttgccgta cttgatccgc aacaatgaga tgggcattgt gaacagggtt aaaattcccc
    19381 cctaaaatcc caacttgttt gcgttttttc tccttgattt ctggctccaa ctctaccttg
    19441 gtaaagggag tcaatagttc gattgtcata ggctagtccc ctttatttct ctataaaaac
    19501 agttatttgg agtttcggtc ttagatttct ttgactttct tagaaatctt gcgattttct
    19561 ttcttgctag attgtttaaa caaaatcaag atgcgtccta ttttttggac tgtatccaca
    19621 ccgatttctt cttccaaaat ttcagctact tcgtggatat tttcatctgt gttttgtaag
    19681 agagtaacct tgattaattc acgcgcatca agagcttgac ggacgctggt tttgatttgg
    19741 tcgttgagtc catttttccc gatttggatg ataggtttga gggtgtgtgc ctggctgttg
    19801 aggaaggcac gttgttttga tgttaatgac ataattttct tccttgtttt tggatagtta
    19861 ttttaggtgg tgagggacgg tcggaactaa ttttccaaag atttcatctt tgaaaaatgg
    19921 atttcctgac ctcacaattg agccttggtc tcaattgtgc cccttgccaa tctacagatt
    19981 ggcaatcaca ccacggcaat aactatcgct atatgagctc actttgttcg ctcagcgatt
    20041 ttgttttaaa taattgcttt tcgtgtgacg acggcgacgc cttctggtgc ccagacggcg
    20101 acttttgcta tgcctgttac acgaatccag cctaggcctg agatgactag gtctgtctta
    20161 tctttaatgg taaagacatg ctggactagc cttgggaaat cttctttttc cttgctattt
    20221 ggtggtgtca gaagagttcc caggtgctta tcgtagaaag cactagctcc ttcaaacttg
    20281 ctacgatgga gtttgagttc attatcaaag aaagcagtaa atccttgctt ttctcctgct
    20341 ataaagtcaa agcgtcccaa accacctaaa aatagggttt gctcaggatt aagctgatag
    20401 gtcttaggct tgatttcctt tttaggactg acatacttga ggtttttggc cgtcaagtag
    20461 tgagccatct ggtggcggtg gataattccc ggcgtatcgt aaatataaga tccgtcgtca
    20521 agcggaatct ctattttgtc caaggttgta cctgggaagc gtgaagtagt gatgacattc
    20581 tgatcacccg tgatttcttg gataatagca ttgattagag ttgattttcc aacgttggtc
    20641 acaccgacca catagacatc gcggccctta cggtagtgtt caatcttgtc aatgacttcc
    20701 ttaatggcat gtttattttg tgctgaagtt aggaccacat cgactggacg aagaccttct
    20761 tcatgggcac gtttcatgag ccactggcta atcttaccag acttaactga cttaggaagg
    20821 atatcttttt tatttcctac caagaggaca tcattgcccg agacgaaacg tggtaaacct
    20881 gggatgacag atccattaaa atcaaagata tcaatgacat tgaccactaa ggcatcactg
    20941 tctcccacct cgtgcaagag cttgaggaaa tcatcgttcg tcaactggac atctgtgatt
    21001 tcattgtagt ggcggagacg gaaacagcgt tggcaataga cttcgccagt ctccaaacct
    21061 ttttcaagtg ccgactgggg ggtaaaacca agaccagctt tatctgtcgt ctgaatggtt
    21121 gctccacaac caatacagag aatttcttcc atagttaaat tcctttttta tatgtaatcg
    21181 gtccgtactt ttcagtgatt tttctcataa cacgacgctc acgagttcgg ttaatctgcg
    21241 ttttgattga gtcatgttgg accaagggtt tgactaaaat tgaccgaatc cctgcacggt
    21301 gggctgctcg tatatctgtc atgagctggt cgccaaccat gaccacttcc tttttgtcat
    21361 agtggaattc cttcatagca cggtcaatac caaatgtgaa gggcttcaag gcccagtaaa
    21421 cgtaatcaat cccaaatttc tcaactgctc gttgaacgcg ttttttggtg ttatttgaca
    21481 ctacgataat gccaataccc gcgtcccgaa ggtcatgtag ccattgcttc atctctggcg
    21541 ttccatcagg gttgttccaa gcaatgaggg tattatccaa atcgaccaaa acagccttga
    21601 ttccctgcgc ctgcaggctt gggactgtca gatcatagac tgcttccaca gcaaaatctg
    21661 gtatataatt ttcaatcgcc attctggctc cttttcttaa ctttttttcg caattttcct
    21721 tagtaacaag gataaaacaa tccacaaacc tgcactagcc aaactgatat agagccaagc
    21781 atggggctca tctgttaaag gtaagggaac attcattccg aaaaagcctg tcacgactgc
    21841 caaaacagct agcaagactg aaatgatagt caaggttgtc aaattgtcat tcagattatt
    21901 gtttagaata ttgttgtaag aggctgaaag ctgctgtaaa atctgagaga ttaggtctgt
    21961 catggatacc agctgatgag cctcaatcat ggcatcatca aactgttctc tctcaatctc
    22021 atcaaaacta cgatacaagg catgaccttg aatatgctct aacaaaatcc gattttgttt
    22081 ggcagctgcc gtcagataaa ccataccagt ctccaaatca gacagggcaa agaggttttt
    22141 cttggtagtt cgctggcgca agaggtcatt gacctcatcc ctactcttgt ccatctgctc
    22201 aatgacagga tagtaggcat tgctgataat ttccagactg gcaaagagaa acttataaat
    22261 cgaaagcgtg tcatggctct ccagataacg agtcatctgt tcaatgacat aggcgttctt
    22321 ggtattacta atggtaatca ggcgacgatg ctcgacaata aaggtcatgg gaaaagtctc
    22381 atagtaggcc ttgtcctttt ttacgtctag gacattatag ataaaggtaa ccgtcccact
    22441 ttcacggtgg taatccatgt gggcgcgctc gtttctatcc agtgcgtatt caatggtttc
    22501 cttgtccaaa ccgtaaattt cagaaaggtc ttctagttta ttcaactttc ctaggtctag
    22561 gtctatccag gtacaaccat tgcccaactg cttttctaaa accatctttt ctccttatta
    22621 aactccctct attgtaccac aaattactta aaataacagg tctagtctgt gcgtgagaaa
    22681 ttgctaacaa ctgtgatatt tcggttaggg acaaagtgaa gggcttgctc ctcgctacga
    22741 agctgtgtcg tacgaattcc cacactgaca accttacccg atacagtaat cggtccattt
    22801 gtcagaacga cctcatctcc cacatccagt tgacgttcaa agaggatgaa aaagccattg
    22861 atgacatcag acagaaagcc ttgggctccc ataccaatcg ctaccccagc aataccagct
    22921 ccagccagca aactagaaac tggcaaacct aaaatcgaca aaatgcagta gagtaaaaag
    22981 aaatatagcg tataattaaa cacattttct agtaaacgtg agatggtttt ttggcgtccg
    23041 acatcatgac gagacatttt tagagaaggt ttgacaattc tctgcaccat ggtatgaagc
    23101 atttttttag caatataaaa tacaatcaaa agcagtaaaa gagaaatgac cttggttaga
    23161 atattctcga taatggttgt cacatctagc ttttcaatat aagcctgaat aaatttttgc
    23221 atataaaact cctttatttc attataccat attttcatca gtctcattct ccataaatat
    23281 tcaaaaaata gacagaaaat tcttgatttt gtctatcatt tatactataa tcataatcac
    23341 tacacaaaaa ggagattatt atgaaaagaa tcattcatgc ttggaataag gcaagccttg
    23401 tcaagcgtat cttgattggt atgctttgtg gggaatccta ggactgaccc ttcctaatct
    23461 ctcagggatt gggctactcg gggatttatt cgttggaggt ctaaaagctg ttgctcctat
    23521 cctagtcttt gccctcgttg ccaatgccct ttccaacatc aaaagggaca agatagcaat
    23581 atgaaaactg ttgttttctt gtatatccta tgatagggac tttcgccgct gctcttgtag
    23641 ctgtactagc aagtttcatc gtccctattg aaattaccct aaatagtgcc aatactgaaa
    23701 ttgcaccacc agatgggatt gggcaggtcc tcagcaacct cttgctcaaa ctggttgaca
    23761 acccagtcaa cgccctgctt actgctaact atattagaat cttatcttgg gcagtcattt
    23821 ttggaatcgc tatgagagaa gccagtaaaa atagtaaaga attgctaaaa actatcgctg
    23881 acgtgacttc taaaattgtc gaatggatca tcaatctggc tccatttgga atccttggtc
    23941 ttgtttttaa aaccatttct gacaagggag tcggaagcct tgccaactac ggtattttat
    24001 tggttctatt agtaacgact atgctttttg ttgcccctgt ggtcaaccct ttgattgcct
    24061 tcttctttat gagacgcaat ccttaccctc tagtttggaa ctgcctccgt gtcagcggtg
    24121 tgacagcctt tttcactcgt agttctgcga ctaacattcc tgtcaacatg aaactctgcc
    24181 atgaccttgg actcaaccca gatacctatt ctgtttctat cccactcggt tctactatca
    24241 atatggctgg agtagcgatt accattaacg ttttgaccct tgttacagtt aacactcttg
    24301 gaattcctgt tgactttgcc acagcctttg tcctcagtgt ggtagcagct atctcagcct
    24361 gtgatgcttc aggtattgcc ggaggttccc tccttcttat cccagttgct tgtagccttt
    24421 tcggtatttc taacgatatt gccatacaaa ttgttggggt tggttttgtg attggtgtca
    24481 tccaagactc atgtgaaaca gcccttaact cttctacaga tgtcctcttt accgccgttg
    24541 ccgaatacgc agcaacccgt aaaaaataac tcatcaaggc aagcctgctc atgtcttgtc
    24601 ttttacgctt ttattctaac ttattaggaa attcttatgt ctattagcca acgtacgacc
    24661 aagctcatct tagctacctg tcttgcctgc ctgcttgctt attttctcaa tctttcgtca
    24721 gcagtttcgg ctggaattat cgctctcttg agcctatctg atacgcgtag aagtacttta
    24781 aaactggctc gcaatcgtct tttttctatg cttctagctc tggctatcgg cgttctagct
    24841 tttcacttga gcggatttca tatctggagt ctcggcctct atctggcctt ctacgttcct
    24901 ttagcctaca agatgggctg ggaaattggc atcacaccaa gcacggtttt ggttagccat
    24961 ctcttggttc aagagtcaac ctctccagac ctcctagtca acgaattcct tctctttgct
    25021 attggtacag gatttgcctt gcttgttaat ctctatatgc cttcacgaga agaggaaatc
    25081 cagcactacc acacgctggt ggaagaaaag ttaaaagata tcctccagcg cttcaaatac
    25141 tatttatcca gaggagacgg acgcaaccga gcacagctgg tagcagaatt agacacgctt
    25201 ttgaaagaag ccctcagact ggtctatttg gatcactctg accacctctt tcaccagacc
    25261 gactaccata tccactactt tgagatgaga caacgacaaa gtcgtatcct gagaaacatg
    25321 gcccaacaga ttaacacttg tcaccttgcc gccagtgaaa gcctgatctt agcgcaactc
    25381 ttttcaaaaa ttgcaggtca actgagccag accaatcctg cttctgattt gctagatgaa
    25441 attgaacgtt atctggaagt cttccggaac cgcagtctgc ccaagacaag agaagagttt
    25501 gaaacccgcg ccactcttct tcaactccta cgtgaagcca aaaccttcat ccaagtaaaa
    25561 gttgattttt accaaaaata tagacagtaa aaaagaaaac cactaaaaaa cagagcttgc
    25621 cagtattctt gaaaagtagt ataattattg catgcgcaat catcttgtga cgcagagact
    25681 gcccgttaat ggactttctt ctatttatga ctctaaaaag aaaggagaca ctatgaccta
    25741 tttggaaaaa tggtttgact tcaatcggcg tcagaaagaa attgaaagtc tcttggaaga
    25801 gaccattgcc caacagagcg agcaaagtct gaccttgaaa gagttctacc tgctctacta
    25861 tctggacttg gctgaagaaa aatctctacg ccagattgac ctgccagata agcttcatct
    25921 gagcccgagc gcagtttcta ggatggtggc tcgcttggaa gctaaaaatt gcggtctact
    25981 cagtcgcatg tgttgccatc aagatagacg ctctagtttt atctgcctga caaatgatgg
    26041 gcaaaagaca ctggcctcgc tacaaaagac tgtcgaagaa agcttggaag caggtttgga
    26101 tttcttgatt taagatgatt ttaaaaaaag ttgcgtgcgc aatcattttt cttgacattc
    26161 tcttttataa ggagtaaaat aaagttagca ttaaacaaag gagttttaaa tatgattgaa
    26221 attacctata tagatgccag caagaacgaa agaactgtga ctttcgagtc ttatgaagac
    26281 tttgaacgtt cgcaacaagc ttgccttatc ggcgtcgcag actactaccc tgtccaaaaa
    26341 ttaacttaca agggtcataa tttggactac catgggactt atggagatat cttcttctat
    26401 ctcatgaaac aagatttaag ccaatataac taaaaaaagg agaaatacaa tggcaaaagc
    26461 aattacagat gcaacattcg aacaagaaac aaaagacggt ttggtcttag tagacttctg
    26521 ggcaacttgg tgtggtccat gtcgtatgca aggtccaatc ttggacaaat tgtctgaaga
    26581 actttcagaa gatgtcttga aaatcgttaa aatggacgtt gatgaaaatc caaacacagc
    26641 tcgtgctttt ggaatcatgt ctattccaac tcttctcttc aaaaaagacg gccaagttgt
    26701 caaacaagtt gcaggtgttc acacagcaga acaaatcaag gccatcattg ctgaattgag
    26761 ctaatcaaac gagagaccaa gtactttctt tggtctcttt tttcttgctc tttgccattt
    26821 ttcaaaaaat atgctag
//
LOCUS       DAVBNZ010000027        26014 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000027 DAVBNZ010000000
VERSION     DAVBNZ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.027"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(15..311)
                     /locus_tag="VQ860_001175"
     CDS             complement(15..311)
                     /locus_tag="VQ860_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119604.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ860_001176"
     CDS             complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ860_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET3119605.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHTIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SVIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3584..4810)
                     /locus_tag="VQ860_001177"
     CDS             complement(3584..4810)
                     /locus_tag="VQ860_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET3119606.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4853..5545)
                     /locus_tag="VQ860_001178"
     CDS             complement(4853..5545)
                     /locus_tag="VQ860_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET3119607.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(5731..7482)
                     /locus_tag="VQ860_001179"
     CDS             complement(5731..7482)
                     /locus_tag="VQ860_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119608.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7472..9217)
                     /locus_tag="VQ860_001180"
     CDS             complement(7472..9217)
                     /locus_tag="VQ860_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3119609.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9423..9719)
                     /locus_tag="VQ860_001181"
     CDS             complement(9423..9719)
                     /locus_tag="VQ860_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET3119610.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9872..10328)
                     /locus_tag="VQ860_001182"
                     /pseudo
     CDS             complement(9872..10328)
                     /locus_tag="VQ860_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10461..11288
                     /gene="xth"
                     /locus_tag="VQ860_001183"
     CDS             10461..11288
                     /gene="xth"
                     /locus_tag="VQ860_001183"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET3119611.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAKNADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11300..11443
                     /locus_tag="VQ860_001184"
     CDS             11300..11443
                     /locus_tag="VQ860_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3119612.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11443..11682
                     /locus_tag="VQ860_001185"
     CDS             11443..11682
                     /locus_tag="VQ860_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3119613.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDPYIYPHEFAVLDPDGYFLRFSE"
     regulatory      12065..12160
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12560..13141
                     /locus_tag="VQ860_001186"
     CDS             12560..13141
                     /locus_tag="VQ860_001186"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET3119614.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGRVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13141..14403
                     /locus_tag="VQ860_001187"
     CDS             13141..14403
                     /locus_tag="VQ860_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET3119615.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14490..15356)
                     /locus_tag="VQ860_001188"
     CDS             complement(14490..15356)
                     /locus_tag="VQ860_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET3119616.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15343..16113)
                     /locus_tag="VQ860_001189"
     CDS             complement(15343..16113)
                     /locus_tag="VQ860_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3119617.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16139..16993)
                     /locus_tag="VQ860_001190"
     CDS             complement(16139..16993)
                     /locus_tag="VQ860_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET3119618.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17150..17554)
                     /locus_tag="VQ860_001191"
     CDS             complement(17150..17554)
                     /locus_tag="VQ860_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET3119619.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(17624..19105)
                     /locus_tag="VQ860_001192"
     CDS             complement(17624..19105)
                     /locus_tag="VQ860_001192"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET3119620.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(19124..20302)
                     /locus_tag="VQ860_001193"
     CDS             complement(19124..20302)
                     /locus_tag="VQ860_001193"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET3119621.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAFDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEVFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20466..21473
                     /gene="galR"
                     /locus_tag="VQ860_001194"
     CDS             20466..21473
                     /gene="galR"
                     /locus_tag="VQ860_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET3119622.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21519..22556)
                     /locus_tag="VQ860_001195"
     CDS             complement(21519..22556)
                     /locus_tag="VQ860_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3119623.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22557..22910)
                     /locus_tag="VQ860_001196"
     CDS             complement(22557..22910)
                     /locus_tag="VQ860_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3119624.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23154..24044)
                     /locus_tag="VQ860_001197"
     CDS             complement(23154..24044)
                     /locus_tag="VQ860_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET3119625.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24177..24713
                     /locus_tag="VQ860_001198"
     CDS             24177..24713
                     /locus_tag="VQ860_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3119626.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24879..25685)
                     /locus_tag="VQ860_001199"
     CDS             complement(24879..25685)
                     /locus_tag="VQ860_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET3119627.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLPN"
BASE COUNT         7804 a         5738 c         4613 g         7859 t
ORIGIN      
        1 gatttgtcct attattattt cattttacta tactctgtta attcatatga gtttaaaccg
       61 atttcatctt taacctcgag taaagcagtt tcaaatattt gtttaagagt ttttgattct
      121 ttacaattaa ccgacaaact ttctgataaa atatgtacaa cttctgagac tgaataacct
      181 atctcctctt tagaattata taaatctgta gctccaccaa taatccaaaa atactgattt
      241 tgtgaaccta caatatcctc attttctacg gaacttcctt gtatcgaaca aattttattt
      301 atctttacca taatacttca acccttttag tgtcaaaagt aaaccaattc ctgtcactgt
      361 taagaatagt tccataatct tgttcgaacc agtctttggt aatttttgtt ttacatctac
      421 tatttcttta gatttattaa tatgattttc agtttctctg ccatctccaa ctattttata
      481 gtttacttct tctgtcttat tatcttgttt attgtcgatc ttgtcattca tttgtctatt
      541 atctttactt gagttaaact ctccgttctt ctggttacta tcaattacat tatttgaatt
      601 agattgtttt tcctctttgt ttttttcttt ttcgttttta tcacttaaat tatttgttac
      661 aattttgtaa agcccattct ccgttacaat attgaaatta ccatcgctat cacgtataac
      721 aggttctttc ccatttgcat tagatttgat gactgatata tacttaccgg ataaattata
      781 aaattggtta tttaaaacgg ttattttacc ctttgaatcc tcaataacaa ttccttcttt
      841 accaccgaat atactattct ctgagactac taaattatca ctaactcgta ataattcaat
      901 atttggttgt tctgtttcct tagaattatt attaattaca ttttttgtta cagtaatatc
      961 tgatactttt cctaaatatt ctgcactatc ttttgcaact cgtatcgctt ttgttttagg
     1021 atcggcaata ttaaatatat tttcggcgat aaccacctgt ttatttaaat ctaataggtc
     1081 tttagtgttt ttatagctat aagcatttac taaagctgct ccgttttctc gataatgtac
     1141 actctctcct ttaactttct tatcaaagcg atttcctttg attaatacat cagtgaatcc
     1201 tgtaaaacgt acacctgcat acatcatgtt atcaaaatga ttatttaaaa ttttaatatt
     1261 agaggggttc tgtgtcgaca atgtttgata gtgtgtacca attgctgtta ctaattcccc
     1321 agatttatca cttttgccaa aataggaatt ttgaatagtc acattttcag attttttccc
     1381 atcatcattc aaggcataag gaaaaccttt tctagttaat ggttcaatct gaatgctctc
     1441 cttacttatg atttgcccat ccttcatcgt tttgggtaag gcttgcccaa gaaaacgaga
     1501 attatcaact aatacatttt tcgaacctgc aatttgaata gtatgccctt gataactatc
     1561 cttgaatgtt acatttttta tagttacgtt atttgaattc ccaatagcaa atgcacctga
     1621 agaatttata agtggtagat tttttgcttt agttccttct tcattcaaag caccgttcat
     1681 atcaatcgta ccaccagaat aactaatatc ttctgttggg ccccattcta cttgcgcacc
     1741 atcatccgta aataaacctg tcataaaaac aatggaaggg tgattcttaa tatttatacc
     1801 atttagaatt gtagctttct cattcaattc taagtgtgta tgacttttta aaaaaacaat
     1861 ttcttttact aaataagttc cttcaggaaa atatacattt cctccaccta gcccttgagc
     1921 tgcagcatct attgcatctt gaattgcttg tcgatcatca tgaatcccat cacctaccgc
     1981 accataatct tttacactta aagcagtatc ttcaaattct tttttgataa ttctgtcact
     2041 tataacatct tccttataac tcttattttc attagtagat gttactgtag attcaactgt
     2101 tctgttgtct aattgtgaat tggaacgaat agtaccatta gagctgatac tattaacact
     2161 taacgaatta tctaaaccat tagtggttga attagaggca atcatttcag cagaacgatt
     2221 ctgattaaca gttggtgaat tatctaaatc attagtaatt gcattagaag actcttttgt
     2281 agccatcggt gaagaactag taacaacttc atccgataaa ataccttggc ttcccaaaat
     2341 tgaaattgcc aatagtaccg agcaagtccc cacctttaat ttacgaatac tgaatacctc
     2401 attaggaaca aaatatttca tcagaacctc caattttttt actattttta acaattgatt
     2461 attacttttc ttaaaataga tagaatgaca ccgctgtcat tatctttatc atatattttc
     2521 caaattgaat tgtcaaggaa taacacaaga aaatattaaa atttatactc ttcggaaatc
     2581 tcttcaaact aggtcagtgc cgccttgccc taagtctagg ttactgactt ggtcagttct
     2641 atagtaaatt gaaactaaaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     2701 tgactgtccc gatcaatttg tcctattctt atttcatttt actatatcta caacctcaaa
     2761 gcagggtttt gagctatcta tggccaactt cctagtttgc tctttagcct tccattcaaa
     2821 agtgatgcta tctttcttag cttgaatata aaatatccca tttactatat ttaaatttat
     2881 tgatatgttg taaattataa atgaaagaac aaataccttg tcatacaagc attcgccagg
     2941 gatatttaca tgaatatcgc tcatatggcg gattgaaact aaaacactac aatatatttc
     3001 ttaaatagac cttctataaa agctagattt aacctcgata aaaatagatg cagtgcttct
     3061 aaaatactgg aatagggcat ataggtaata gtagacaagt gttttataga ttgtctcgcg
     3121 ggagatctaa tgatgtatag caagcatcac taaacatata gaatatttgt gttattataa
     3181 tatcaatatg ctataaattc tatcatgcaa aagaatgact agaacatgaa agacaggcac
     3241 aaaactttga acaatattct gaaaacaaaa aaagacgcga gtttccacaa tctcactcat
     3301 ggaaactcac gtctttcaaa aaatagggtg aattaaaaac tagaacaaga cactagattt
     3361 tctaaatgat gtctagtaag gattctaaat gctacaccaa attgctcaca tcttatttca
     3421 aaccacggga ctcccacaag aaaggaaaat cctataaaaa ttctctctct gaggagagag
     3481 aggcctcaac tacaggtgta aactattatc aattgaaaac aacagttttt acactcaatt
     3541 agacttttta gggacaggat cactttcgct tgactgtagt ttgtcatttt tttgataaag
     3601 ttagcacttt ttcagaaact gttttgaaag tctcaatgat atagtctact tcttcatcgc
     3661 ttaatttagt atgaagaggg agggtaattt cattctcaaa gaaggcatag gccttaggat
     3721 agttcgtcat atcaaatcca agattcttat aggctgtcaa gagaggaagc ggtttgtagt
     3781 gaacattact tgcaattcct gctttagcca attcttggat gatgaggttg cgttcttcta
     3841 ggcttgctcc ttctacacgg gtgatgtaga ggtggcgtga agattcgaca gtttcagtct
     3901 tgtgtgccaa aggatggatg cgagaacctg caaaaccact atcatagcgg tccacaatat
     3961 ccttacggcg ttgcaacaaa cttggatagc ggtccaattg taccaaacca agtgaagcca
     4021 tgatatcggt catgttgcac ttataggctg gtgtaacgat atcgtattcc catgacccca
     4081 gttgcatctt ggcaagagca tccttagttt gcccgtgaag ggaaaggatt tggaattcct
     4141 tgtacatctc ttcgtcatca atcactggat tggctttcca agtcgcactt ccaccttctg
     4201 ccgttgtaaa gttcttaacg gcatggaatg agaaggaagt aaagtcagcg atagaaccag
     4261 aaggttgtcc tttataagta gatcccaaag cgtgggcact atcagagaca atgacaatac
     4321 ggttaaaggc cttttgccac ttgcttgaag cggtaaagaa gtcacgtttt ttctccacga
     4381 cttggaacaa acggtcataa tcgcaaacaa tccctgcgag ctctactggg ataatcacct
     4441 tagttttctc agtgatagct tgctcaagca ggtcatagtc catctcaaac gtatctgctt
     4501 ggatatccac catgacaggg gttgctccca cgtgcgtaat gacactacat gaagccgtat
     4561 aggttatggc tggaacgatg acttcatcac caggtcccac ttcaaaaacg cgtaaaatca
     4621 actccagagc ggctgtcgca gagttgagac aaacagtctt aggtgtctgt gtgtaaagag
     4681 acaagcggcg ctccagttct tttgttttag gacctgttgt gatccaacca gaacgcaggg
     4741 tatccgctac ttcagcaatt tctgcttctg tgatatcagg cggtgaaaat ggaatattgt
     4801 aatttggcat tgatttgctc cttttatctg tactcattct cttatgacta ctttatttta
     4861 gtaccttaaa cacggtttga aacatgattt tgatgtcccc aaagaaacta aactctcgga
     4921 gataggcgag gttatagcgc atcttttcag gaagaacatg ctccacatag gcctgatcaa
     4981 ctgacagacc tttctctgtc atttgactga tgatggtgtc ctcatccttg tagttgatgc
     5041 tggctggaga ggtaattcct gcttgcaaga gcaaggttgc catcatttca gtgctatact
     5101 gctctgtata acgtggcact tcaggtcgtg taccgacaaa ggacatctca cctttaagga
     5161 cattgaccaa ctgaggcagt tcgtccaaac ggacacgtcg gatgaaattt ccaaccttgg
     5221 taatacggct atcgttagca gaagtcacca gatttccttt tttatccgca tccgtcacca
     5281 tggtacggaa cttccaaatc ttgaaccgac ggttgtactg ggtcacacgc tcttgcttgt
     5341 aaatcactgg ccccttgcta tccaacttga tccaaatgct caagatgaga aagatgggag
     5401 aggtcagaac cagtaagacc aaggccaaaa cccagtccaa gcaacgcttg aaaatcagcg
     5461 aacccttcct tttagagaca agctggtagt aagactcaac ctcgcttgat ttcatttcca
     5521 caggcaagtc ttcccatttc agcatgctgt tctcctttgt ttttattata ctatttgtca
     5581 acactttttg tcaacacttt tcattatacc acaaaatgga aaaggcggtg aaaaaaatct
     5641 gtaatttgaa ggatttcctt ctagtactca atgaaaatca aagtacagct ttgagattgc
     5701 agataaagct gacatggttt aaagagattt tcaaagagta taggccatgg cccctgcctg
     5761 caaactatac atcttgtgat aggttcctcc cagagccaag agttcctcat gggttccact
     5821 ctcgataatg cgtcccttat ccaagacata gatgcagttg gcgtcttgaa tagtagaaag
     5881 gcggtgagct atagcaatag ttgttcggcc ctgtctcatc ttcgccagag aagcttgaac
     5941 caagctttct gtttcagagt caatattggc tgtcgcttca tccaaaatca ggattttagg
     6001 ctggctggcg actgttctag caaaggcaag aagctggcgt tgcccagtag agaagctcga
     6061 accacgctcg gaaacagggg agtcgtaccc ctgaggaagt tcttgaataa aggaatctgc
     6121 atccacaaag gctgccgcag cctgaacctg ctcatcactg atttcttggt acatggcgat
     6181 attggactta atagttccat gatagaggaa gggttcctgc aagaccaaac cgatgttttt
     6241 tctcagctct tcttgactga aatccctgat atccacatca tccaagagaa ctctccctga
     6301 ctggaattca taaaagcgca tgaggacatt gataatagac gatttccctg aacctgtatg
     6361 acctacaaag gcaatggttt cacccttatt aacagagaaa gaaatgtcat ccagaatcgg
     6421 atgtttaccg tcatatgaga aacacacatg ttcaaagcgg atattgcctt cttggacttt
     6481 ggcttgccca ttttcttgaa gaggttcata ggtcctctcg tctaccaggg caaagacacg
     6541 acctgcagaa accatagacg tttgcagtgt tgaaaagttt tgcgtcacct caatcaaagg
     6601 gtcaaagagg cggttgatgt actggataaa agcatacatg gtcccggccg ttatcccgat
     6661 agaaagacca cgatagccaa aataggccat caagacagca taacctagaa gtttcaacaa
     6721 actcatggca ggtctcaaaa agagggcatc caaggctaca gaacggttgg catagaccaa
     6781 gtgctcttgg ttgatttcat caaattctgc ctgcaggcgc ttctcttgat taaaggcctg
     6841 gattattctg attccctcga tgttttcagc cagcttgcta ttgatatctg acaagagact
     6901 tctggttttc tcaatgattt tcactgattt tttccgatag agattgacca aaaggaaaat
     6961 caaggggaga aagagcaaga ctaatgctgt caaacgaaaa tccaatacca acatggtata
     7021 aagggttgtc agaaagatga aaactgctga gataaagcta gataaaatcc cagaaaacat
     7081 atcactaatc gtctcggtat cgttggtcaa acgagaaacg atagaacctg ctggcgtctt
     7141 gtcaaagtaa gacatgccca gtttctccat attggcaaag gcatcccgac gaatatccct
     7201 aacaatactg taagacacgc gcgcaaagag aagattgccg acatactgaa ctacagtttg
     7261 taggatgtag agaccatagt agaccagcaa aacggtaacg gctagttggt taagattgct
     7321 gagatactgg tcgataaagt gggaagccac gaggggtatg acacttttaa tgaccgtcgt
     7381 cgctaggaga aaactgagtg ccaaaaaggt caggagtcta taaggcttga gataagacat
     7441 caagcgcttc aatacagccc attgttcttg tttattctgc atcttcttct cctttcattt
     7501 ctaactgctg agactggtag gtttgggcat accagccatc catcgctagc aagtcttcgt
     7561 gcctgcctcg ttcgataatt tgaccatttt gtagaactaa aataaaatct gcatggacaa
     7621 cagcactgag gcgatgggca gttataatgg ttgtcttgtc ctttcgcgtc tccttgaggt
     7681 tgtcgataat cgcatactct gtcttggcat ctacggcgga taaggaatca tccaaaatca
     7741 agatatcagg gtttaaaatc atagcccgac tcatagccaa ccgttgcttt tgaccaccag
     7801 aaagactgac tcctttttca ccaatcagcg tatcaaatcc ttgaggcatg tctacaatat
     7861 cttggtaaac tcgggctagc ttagtagctt cctcaacctc tgaaaggggc aagttaggat
     7921 tgccaaagcg gatattgtct aggattgaag tcgcaaagag aaactggtcc tgaggaacat
     7981 agcccatgag actgcgaagt tctgtcaaac gatagtcccg aatatcgtga ccgtttagat
     8041 aaatggcacc cttatccaca tcgtattcac gcaagaggag cttgattaag gacgttttcc
     8101 cagagcctgt ctgcccaacc aagcccagtg tttgcccttt tgccaaacta aagtgaatat
     8161 ccgtcagtgt ttcctcattt tcaaaagcaa agctgtcaat ggcatactcc aaacgcccat
     8221 tttcaatacc atccagagga aactcagggt cttgtacagg agattcctga gacaaaagat
     8281 tttcaatccg ctggtaagaa accttccctc gctgagtagt attaaagagg aagccgatgg
     8341 ccataagagg ccagaccagc atatccaaat agctgataaa ggtgactaga ttaccaactg
     8401 taatctgccc ttcctgaacc atcaaggagc caaccaaaag cgttaaaaca taggacgaac
     8461 caacaaacaa gagaaccata gggtcaaaga gactatcata tttcatggtt tgcaggttct
     8521 tttggaaggt taattcattg actgcctgaa aagacttcaa ctcgtctgcc tgataaccga
     8581 aagacttggt cactttgata cctgatacgg actcctgtac cttgttattg agttcagaaa
     8641 aagcagcttg ggattcgcca aaggccttat gagtctttct ccctaggcga ctagtcgcat
     8701 aggccatgaa aggtaggggg agaatggcaa caagagtcat ctgccatgag atgctaaaga
     8761 gcatggtcaa caaagtcacc agagccgtga tagaggcatc caccgcagac atgacaccgc
     8821 cacctgctaa acgagtcaag gcattgatat cattggttgc gtgtgccatc agatcacccg
     8881 tccgataggt ttgataaaag gctggcgaca tttttgtgaa atgcttaaac aagcgagacc
     8941 gcatgatctg tcccaagcaa taagaggtcc caaggatata catacgccac acatagcgca
     9001 aatagtacat accaaaggct gcaagtagca agtaaaatag gctaagaagg aggtcctgct
     9061 gggttaattg ccccgatgtg atggcatcaa tgactcgccc cataaccata ggaggaatga
     9121 gattgagaac ggaaaccaag accagggcca caatcccgac tagataacgg tgtttttcta
     9181 acttgaaaaa ccaccagagt ttttgaataa tggacataaa atccctttct gattgcaaat
     9241 ggaaacctga ggccaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
     9301 ctgctcaaag cactgctttg aggttgtaga tagaactgac gaagtcagta acctacatac
     9361 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtacaagac cccaggtttt
     9421 tcttattcat aagttacgac tgtaacagca cccttgtcat attcagcaat aaagatattg
     9481 gctacattgt catgcccttg tttgctgagg ttatcaagca accactcttc gctacgacca
     9541 atcgattcca agacgtctac ttgaatcaca ccgtcagtca caactggata cttaggattt
     9601 tcatctccca tttgcacaac gatgagttgc ccattttgct cttgcacagc tcgtttgact
     9661 tgcttcatct ggaaaatccc ttggctacga agtttgaggg ctacatccga tgcagacaaa
     9721 ccaactgaac gacaggctta tgggtcaata ttcccatttt tgataaggag agttggctta
     9781 ccatcaatca aacgtttcac aaagtgaaca ttgttgttga gctatttgag agtcaagatc
     9841 agtttgatta aaatttcgat ataattaagt gtcatttgtt cacatccacc agttcaattg
     9901 cgtctgtctt atacaattcg actttctcta acaggtactt gtctggctca cttccgttta
     9961 gggcacgata atagcgatct cccaccttga taagtgcgcc atctgtgttt gtggaagtat
    10021 taacatggac ttctgacttg tctactccca aatctttgga aacaacctcg atgaaatgaa
    10081 gtgaagtttg aaatttattg ttagaaactt gattgttttg ataagtcgtg atgctgacca
    10141 aaagcatagc taaataaggc cagagctgaa atcatgacca actcacgaaa tttggttcct
    10201 tttttatcat ggtatgcctt gaaagcaaaa aaaactgtca cagctaatag aacaatccca
    10261 aagccaacca tgataccatt ttgctgaccg atttggctga gtacatagtc ataagagtag
    10321 aatttcatgt attttcactc cctttcataa aatcattctt aattataaac gaaagagagt
    10381 aatttttcaa accatacgtt ggggaaatag ctcttttttt ggtataataa aatctataat
    10441 ctgaatgaaa aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg
    10501 ccctaactag tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg
    10561 ctaaaaatgc tgatattatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa
    10621 agaaacacgt ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgttctt
    10681 cccaagagcc tgcccgtaaa ggctatgctg gaaccatgtt tctttataag aaagaactta
    10741 cacctactat cagcttccca gaaatcggtg ccccttctac catggacttg gaaggtcgta
    10801 tcatcactct agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg
    10861 acggtctcaa acgcttggaa gaacgccaag tctgggatgc caaatatgct gagtatttgg
    10921 ctgaactaga caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg
    10981 aaatcgacct tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac
    11041 gtgctggatt taccaacctt ttggcaactg gatttacaga caccttccgc catgttcatg
    11101 gcgatgttcc tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca
    11161 atacaggctg gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta
    11221 aatctgatat gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg
    11281 atttgtaagg attttctata tggactacaa tgcggtcatt cccgagttgc ttgtatcgaa
    11341 tatcgaacag tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg
    11401 tccagaagaa aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca
    11461 aaggatcaac tagctgaact gacctatcca tttggtcgtg gagtcaatct ctcctttggc
    11521 ataaaggatg tttcaaaact ctatcaaaga gtgatgaagg caaactatcc tatttatcgt
    11581 cccttgacca aaagaaagtt tcgtgtcagt gatccctata tctatcctca tgaatttgca
    11641 gttttggatc cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa
    11701 aagtctttaa agttagaaaa aggcatattg tcaggtgttt aaaaacttga tagtatgcct
    11761 tttatgatgg aaaaatcttc taatactctt cgaaaatctc ttcaagccac atcaacgtca
    11821 ccttaccata ggtatatgat actgactctg tcaattctat ccacaacctc aaaacagtgt
    11881 tttgaggttg tggatagctt cctagtttgc tctttgattt tcatttagta taaatgttag
    11941 cttacaacgg agtttttgtt caccccctct tctgtttgtt cgttttttaa atcaaaacac
    12001 taacaaaata gttgatttat aaagttattt agtgtaaaat aaaaacattg gctcaagcct
    12061 atttaaaatt gaatatcgtt ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa
    12121 ggtgccggaa cacctaacaa taagtaagtc agcagtgaga tatggccgtt tttgccatgc
    12181 ctatttgggg gacttactta gagattaagt aggtcttttt tgaatatttt taatatttcc
    12241 cttaattagt gcggacggga ggtgaaatta tcctgtgaat aatttcagga atccagggaa
    12301 tttcatccct aatttttgag cccctagctc tttcatttct aggcttaggc taaaatagtt
    12361 ccccgaacta ttttactctc aaaaatcccg tcatagacaa taacaagatt attgtctatg
    12421 ataccactac aacgggaaat atttgataag actcgcttcg ctcgtaatag ttttatcaaa
    12481 tatatagtat tagcaaaagg gatcactata gaaatattta aacaacaagt aaattaactt
    12541 ttagacttta ggaggtctta tgaaattatt agaagagcgc atcctcaagg atgggcatat
    12601 cttgggtgat aacatcctca aggtagattc ctttttaacc caccaagttg actttagctt
    12661 gatgcgagag attggtaggg tttttgcgga aaaatttgct gctactggca ttaccaaggt
    12721 cgtaaccatt gaagcgtcgg gtattgcccc agccgttttt acagctgaag ccttaaacgt
    12781 tcccatgatt ttcgccaaaa aagctaagaa catcaccatg aacgaaggca tcttaactgc
    12841 tcaagtctac tcctttacca aacaggtgac cagcaccgtt tctatcgctg gaaaattcct
    12901 ctcaccagag gacaaggttt tgattatcga cgatttcctt gctaatggcc aagctgctaa
    12961 aggcttgatt caaatcatcg aacaggccgg tgccacagtc caagctatcg gtatcgtgat
    13021 tgagaaatcc ttccaagatg gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc
    13081 acttgctcgt ttggatcgtt ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta
    13141 atgcaaactc aagaaaaaca ctcgcaagca gccgttcttg gcttgcagca cttactagcc
    13201 atgtactcag gatctatcct ggttcccatc atgattgcga cagcccttgg ctattcagct
    13261 gagcagttga cctacctgat ttctacagat atcttcatgt gtggggtggc aaccttcctc
    13321 caactccaac tcaacaaata ctttgggatt ggactcccag tcgttcttgg agttgcattc
    13381 cagtcggtcg ctcccttgat tatgattggg caaagccatg gtagtggcgc tatgtttggt
    13441 gcccttatcg catctgggat ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc
    13501 aatctcttcc catctatcgt aacaggatct gttattacca cgattggttt aaccttgatc
    13561 cctgtcgcta ttggaaatat gggaaataac gttccagagc caactggtca aagtctcttg
    13621 cttgcagcta ttactgttct gattatcctc ttgatcaaca tctttaccaa aggatttatc
    13681 aagtctatct ctattttgat tggtctggtt gttggaactg ccattgctgc tactatgggc
    13741 ttggtggact tctctcctgt tgcggtagct ccacttgtcc atgtcccaac tccactctac
    13801 tttgggatgc caacctttga aatctcatct attgtcatga tgtgtattat cgcaacggtg
    13861 tctatggttg agtcaactgg tgtttatcta gccttgtctg atatcacaaa agatccaatc
    13921 gacagcacgc gccttcgcaa cggttaccgc gcagaaggtt tggccgtact tctcggagga
    13981 atctttaaca ccttccctta caccggattt tcacaaaacg ttggtttggt taaattgtca
    14041 ggcatcaaaa aacgcctgcc aatctactac gcagctggtt tcctggttct ccttggactg
    14101 cttcctaagt ttggtgccct tgcccaaatc attccaagct ccgtcctcgg cggtgccatg
    14161 ctggtgatgt ttggttttgt atctattcaa gggatgcaaa tcctcgcccg agttgacttt
    14221 gctaacaatg aacacaactt ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc
    14281 aacaacagta atctctttgt cagcatgccg acagccttcc aaatgttctt ctcaaacgga
    14341 atcgtcgtag ccagcctact cgccattgtc ctcaatgccg tattaaatca taaaaagaaa
    14401 taagaaaaag aggtgcgagc ctcttttttg tttatcacaa attgattata aatacaatca
    14461 atcccaattc ccatctaatt gaattggacc tatttcaaat tctttaaaat attatgttcc
    14521 aaatcgttaa tattatataa gaatggtaaa atatcaaatg tttctcgtaa attattctta
    14581 gccttatacc aaccttgtcc atcagtaatc cacataaact caacattagg aatagcttta
    14641 atttcttcag caatcatttt gtaagatcta gccgtctcat ttaattttga accacttcct
    14701 gaataaaaat taacctcaat cagataaagc acttgttcat tttttatgac aaaatcaaaa
    14761 cgtttcacag tattcccatc attcgtaata gcagataaat cgacagaaaa aatttcctct
    14821 atttcatttt gttcaatctc tttaaataaa ttctctccta aaatataccc ttcagcttca
    14881 agatagcttt gaacaatatt ttccatcgca tctccagtcc gatttttgcg cccattagta
    14941 tccataccaa cctcaacacc tgtaacgtag tcaactaaat ttgatactaa atgattttgc
    15001 aataaatcaa atatacctga tttttccaaa aacatagtat attcttcaat actatagttt
    15061 cgtttactaa aatcaaaata gaaatctttt atcggatcct taacaataat cgtatctctc
    15121 aaacgtttag caataagtag aggcacaact ttcaaaattt ctggataatt ttgatataag
    15181 tctaaaaaat cctcttgtat atttttacta ccaataagac tattcataat atttagagca
    15241 acttttatac tagatacatt tttataaacc ttaggaaaat ctgtataata agtccagtca
    15301 gctactgtgt cggtcatcgt tgacaaccac tcatcaaaat ttctagtttg tttcattttc
    15361 tgcctccaac ctcttccttg caatttttaa atattctttt tcagcatcga tacctataaa
    15421 tcttctacct aaccgcttcg caacaacacc cgtagtgcca ctaccaacaa atgggtctag
    15481 aatatagtca ccctctttag tagaggctaa aataatgcgt tctaacaaat actctggttt
    15541 ttgagttgga tgtttcccag cccatttttc aactttcttt gttaaagaac cggtccagac
    15601 atctttcatt tgttttccat cattcaattc tttcattaaa tcataattgt agtaatgacg
    15661 agctttttta tcattttttc tggcccataa aatggtttca gtagaatggg taaaataacg
    15721 acaagataaa ttgggggcag ggtttgtttt ctgccaagta atattattca gaattttaaa
    15781 accttcttgt tctaatgcca ttccaactga gtatatgttg tgcaaactac ctgaaatcca
    15841 taccgtccca ttaggcttca gaacttcttt tgctaggcga atccatttac gattaaactc
    15901 atgtttttct tcgaatgaag aaattttatc ccaatctcct ttatcaacag aaacaacttg
    15961 tcccccagaa ttagatattc caccattact taaaaaataa ggtggatcag caaaaatcat
    16021 atccatactt tctggtttca tttttgataa gaacttgaac gtatctgaat gaacaagaat
    16081 catcttattt ttattgtagt atggttttgt cataagaaca cctccatact tatattcgtt
    16141 atttttcata atttgtgact ataatttcag aaatttttcc tcgacttgaa gattttgctc
    16201 cattagttcg ggtagcttca acataatgta tattaaaatc cttatacaac tcctctacta
    16261 aagcactaga agaatttgat aacataacat aagctcctgt atcactcaat ctcttaaagg
    16321 catctcttaa tcttacttga tctgcaaaag agaatccctc atgagtataa gacgtaaatg
    16381 cactcgtctc agacaatgga atatatggag ggtcaaaata cacaaaatct cctgttcgaa
    16441 catctacaat tgccttttca aaatctccca ctttaatttc tagttgattg ttatttatat
    16501 aaactgaaat agcagatatc aattcctcat caacaatttt aggattctta taacgtccat
    16561 atggaacatt aaattgattc ttagaattca cacgatatag accattaaag ttcactctca
    16621 acatatatag aatacgtgca gctctttgta cttcggacat catatctatt ctttcatcac
    16681 gatctgcaga acgtaaatct aaataatatt cttttgaatt atattcctga tgaactttca
    16741 aaatttcaat caattcttga ggattgtcct taatttgttg atagcaattt attagttcag
    16801 cgttaaaatc attaataact gcatctttag gagccaaatc aaaaaataaa gctccacctc
    16861 caacaaaagg ttcgaaatac ctgttatagg ttttaggcat taattctcta ataacaggca
    16921 ataattgtct tttaccacct gtccatttcg tgaacggttg taaagtaact ttctttattt
    16981 cttttatctt catgctttta attataccat agaaattaaa acacaactct tgtattttct
    17041 accacattac taaattttct attttagaat taaatcatat caatatcaaa aaatgagtaa
    17101 ggcaaatctt ataaattcca aaattcacct cactctatta aattactctt tatatcctta
    17161 cctgtctttc ttctgaccgc tggcctgtga caaacatggt aaaggttgct ttacagacat
    17221 ttctgccctc ttgattggtg atatccacat ccatcacaca ggttgtacga ccttgatgga
    17281 cacattctcc tttaatggtc aatacatcgt cgagttttcc tgccttaagg tagttgatag
    17341 aggattggag tgtcacccca tcaagtccca gcgagataac caccaaacca ctgatttggt
    17401 cacatagcgt gaatagatag ccaccatggg cattgccata gtagttgagc gacgagttca
    17461 ctactttggt cgtcaccaca acgtgaccat ctctcatttt ttcaatttcg taattttcaa
    17521 aggcagatat agcgtcaaaa tgaaagtctt tcatcgtttc ctcctgatat ttcaaacgac
    17581 actatgatac tactttttat aggactgtgc aaggagaaag ctcctagtct agtaaaattc
    17641 cgacctgttc cacaaagcgc ataaaggctg tctgaccttg ttctgtctgc ttgtagactc
    17701 ctgcatcctc aagtacacgc acaaagatag cacccacaga gtccttgacg attgcaaggg
    17761 ctttttcttt atccgttagg tctggatgtt gggatttgag ttggtctgcc cactcctgat
    17821 gataatcggc aactgtaaca gcttctccta caagatagct agcgacttgc tccacttctt
    17881 ctttcagacg tggtggcaag attgccaagc ccatgacctc aatcaagccg atattttcct
    17941 tcttgatatg ttggacatcc ttgtggggat gatagatgcc atcaggatgc tctgctgaag
    18001 tctgattgtc tcgcaagacc aagtccaact caaactgtcc atcacgctta cgcgctattg
    18061 gtgtgatggt gtgatgcggt gtcccgtctg tctctgctaa aatctgcaca ctagaatctg
    18121 aatactgacg ccattcctgg aaaatcttat cagctaagtt aatcaaatcc tctttggaat
    18181 ccgaagtcaa gcgtaggaca gacattggcc acttgataat tccagccttg acctgctcaa
    18241 aaccagcaaa tcggaaggtc ttttgcaagg gagccaattc cataggaaat acgtgacggc
    18301 ctccctgata atgatcatga gttagaatag agccccccac aatcggcagg tcggcattag
    18361 atccagcaaa atatcctgga aactgctcta cgatagccaa cagacgttca aaactctgac
    18421 gactaatggc catgggacga tgctggccat ctaaaaagat acaatgctca ttaaagtaag
    18481 catagggcga atactggaac ccccattcct gaccaaccat ttcaaaacgg ataatccggt
    18541 ggttgctgcg agctgggtgg ttgacccgac catggtaacc ctcattctct aaacaaagtt
    18601 gacactgagg ataattacta gcttgcacca acttggctac cgcaatctct ttcggatcct
    18661 tttcaggctt agagagattg atggtaattt caagttctcc ataatcagat ggaacacgat
    18721 aagcgatatt tttagcaatg gccttgagtt tgatgtagtc atttttccga ctgagttgat
    18781 aaaaatcctc tatcgcttgc tcaggagagt aggcataggc ttcccagaag tcacgattga
    18841 cctgactcgg acaaggagtc accaagtcca tcagttcagt accaaggatt tcacgcgcag
    18901 tctgactatc ctcaatcgtc tctaatcgaa cggcttcctc aactagctgg tccttgaggt
    18961 caatcaattt atccagattg gtctcaactt ccaaaacacc ttctcccact cgtgccaaaa
    19021 cacgattggt caggtagatt cgatccattt cctcaaatga actttcagaa atgacatgtg
    19081 ttacaaattt atctactaag gtcactatag agcctccttt tgactagtca aggacgcgag
    19141 tgccacctgc aacttcagcg atatagaagc ttggagcgta tccaactact tcctcgtagt
    19201 gtttgcctac agcttcctta aagacctcaa cagtatcttt ttgaaccaag gcaatggcac
    19261 agccaccaaa accagcccct gtcatacgag caccgagaac tccttcttgt gcccaagctg
    19321 tgtgaacaag ggtatctaat tccaaaccag ttacttcata atcatgctcc agagaaacgt
    19381 gtgacgcatt catcaaacga ccaaatgttt ccaaatcacc tgcttgaagg gctgcttgag
    19441 ctttaagggt gcgttggttt tcaagcacag catggcgagc acgtttcaaa cgattttcat
    19501 ctttaatcag atagctatat tggtcaaagg cccactcgtc caattcaccc aaggtctgaa
    19561 tatccaaggc aacttgcaac tcttccactg ctttttcaca ctcagcacga cgttcattgt
    19621 atttagagtc cgccaattca cggcgtttgt tggtgttcat gataacaacg acattgtcct
    19681 tcaaatcaag tggcaccaaa tcatactcta aggtgttggt atcaaggtaa atagcacgtt
    19741 gatcagcccc cataccaata gcaaactggt ccatgatacc agagttgact ccgataaagt
    19801 tgttttctgt ttgttttccg attttaacca aatcgagacg ctctaatttt aaatcaaaga
    19861 gatgctctgc cacgactcct gtcaagagct ccaaggatgc tgaagaagac aaaccagcac
    19921 catttggtat attcccataa acataaaaat caaaaccttt gtcaatcacg tgcccagctt
    19981 cttgcaagaa atgaaggaca ccttttggat aattggtcca gttgtgctct ttttcaaact
    20041 tgaggtcagc gagaggcact tcgataatgc ccttgtcctc aaagttagct gagtagaaac
    20101 gcaaaacttg gtcgtcacgc ttacgagctg caccgtaagt tcccaaggaa atagcagcag
    20161 gaaaaacgtg cccaccgttg tagtctgtgt gttcaccaat caaattgata cgacctggtg
    20221 aaaagaaagt ttggtctgct tcttgaccaa aaacagcaag aaagtctttg cgaagagttt
    20281 cagcagtaag atgttgtgtc atatgatttc tcctttgact gtccgttaag ccaccttaac
    20341 gtgtaatcgt tttcttctat tgtatccaag ggatttccca aggtcaatcc tttttactaa
    20401 aattttacta aaatatcagt aaaaagcaga aaaatatgat atactaacct aatcaaggag
    20461 gatttatggc taccttaaaa gacattgcac agctagcctc tgtctctatc gcgaccgtat
    20521 cccgtgtcct caaccgcgac cagagcctat ctgttacaga agaaaccaga caccgtattt
    20581 taaccgttgc tgaagagctg ggctacacca agcacctcaa gacaggcgag tcccataaac
    20641 ccaagcaaaa gattgccatt atccaatggg tcagcgaaca aggggagctg gacgacctct
    20701 actactacca gattcgccta ggaatagaaa aaagagccca agagttggac tatgatatct
    20761 tgcgctattt taatgaccat ccttttacct taagcgagga agtgattggg attctctgca
    20821 ttggaaaatt tagccgagct cagatttctg cctttgaaga ataccaaaaa cccctggtct
    20881 ttctagacag tgatacactt tccctgggac atacctgtat tatcacggat ttttacactg
    20941 ctatgaaaca ggttgtcgat tatttcctca gccaaggaat ggaccgtatc gggattctaa
    21001 caggccttga agaaacgact gaccaagaag aaatcattca ggataagcgg ctggaaaatt
    21061 tcagaaacta cagtcaagca aaaggaatct atcatgatga actggtcttt caaggaaact
    21121 ttactgccca gtctggctat gacttgatga aggaagccat tcagagcttg ggagaccaac
    21181 tcccaccagc atttttcgca gccagcgata gtttagccat cggtgccctt cgtgcgctcc
    21241 aagaagctgg aatcagccta ccagaccgtg tcagcctcat ttcctttaac gacaccagcc
    21301 tgaccaagca ggtttatcct cccctctcca gcatcacagt ttatactgaa gaaatggggc
    21361 gagcaggtat ggatattctt aacaaggaag tcctccacgg tcgcaaaatt cctagcctga
    21421 ccatgctggg aaccagactg acattaagag aaagtaccct aaatcaagaa taggataaca
    21481 taaaaaacga atagagttct aaaactccta ttcgtttttt attcgattac aatcatagac
    21541 ttaattgtct tacgttcatc catatcttta taggcttggt cgatatcttc cagtttataa
    21601 cttgaagtaa agacgcgacc tggattgata tcaccatcaa ggacggcttt tagtaaaaat
    21661 tgcttatcgt atgttgtagc agaagctgcc ccacctgcta cagagatatt ttgcataaat
    21721 gtcgaaccaa gagcacgatt attatagtgt gggactccta caaagcccat acgccctcca
    21781 ttatgaagaa cacctagcgc ctgttctata gcagcctccg taccaacaca ttcaagtgct
    21841 gcatctgctc ctccaccgag gatttcacgc accttggtaa ttccttcttg accacgttct
    21901 gcaacaacag ctgtcgcacc tgactccata gccatctttt gacggtcttc atgacggctc
    21961 ataaggataa tttgtgatgc tccacgcatc ttagccgcga tgacagcaca ttgaccaaca
    22021 gccccatcac cgataacaac aaccttgtcc cctttttgaa catttgcaac acgcgccgca
    22081 tgatagcctg tcggcatgac atctgcaaga gtcaaaaggg acttgagcat cccttctgta
    22141 tagtcagaag gttgaccagg gattttaacc agcgcccagt ttgcatagtg gaagcgaata
    22201 tattctgcct gaaaatcacc ccccaaatta ttgccaatat gattgtcgca agaaccgtca
    22261 aatccagcaa gacaggcatc acactcacca catccatgtg taaaagggac aatcacaaaa
    22321 tcacctggtt tcaccgtcgt aatggcttcc ccagcttctt caacaatccc aatcgcttcg
    22381 tgtccactat ttttgtgtcc agctttcgtt tctggattac ggtacctcca taaatctgaa
    22441 ccacaaacgc acgcacgaac cacacgaata atcacatcat ccgcttctat tatttgcgga
    22501 cgttcaatgc tagcaagtcc aacctgacct gcctttgtat atactgctga tttcatttaa
    22561 aattttcctt ccttataaag tttaattttg agatttaaac gatttaaagc tgtctgtagc
    22621 tgagacaagc gctcctctaa tttttgcttt tcctcttcta aaataccaag cctctcctct
    22681 ctcgtttcat ctcccttttg gtagagcgac atatagtcaa ctaaactatc tacagagaca
    22741 cccgccgaac gaaaacactt aataaattcc agcgcttcga tatcctgatc ttgaaaatca
    22801 cgaatcccag tagcagtacg agtaatcggt ggcacaagac caacccgttc ataataccga
    22861 atcgtatccg ctgaaattcc caacaaatca ctggcagatt taatattcac acgctaacct
    22921 cctctcattt cattcactga attcacgcta ttctaactca cttatcttat tatataactt
    22981 tgagttgact ccaagtcaag cattttgtat ctaatcgaaa aatttttatc attaacaatc
    23041 atatatctgg agtttataca atgctcttct cttaccaatt tttgaaatat ttaaataata
    23101 aagaaattac tctattccaa ataagatagt acccaagtat ttttcacttt tttctaatgt
    23161 tgatgctcat aactccgttc caagtcacac acctttcgct tatgggtttg gtgagtttct
    23221 aggtcagcat caatttcaat ggtaatattt tgaaaaccac aatcttttag gaaaattcga
    23281 atagactctt tacaagtttc catatgttcc atttctttta gacaaacatg gacaatggca
    23341 tttttttcca aagcatccat agtccagaga ttaagctgat taaggctggc cacattgtcc
    23401 aatcgttcca ggccactctt tacttgcttg atatcaagac cttctggcac agcatccaag
    23461 aaaatcttga gtgtagacca aaaacgtgaa agggcttttg aaagaataaa gaaagaaatg
    23521 acaagggaca aaagaggatc taggatatac cagtccgtaa atcgaagaac aatcgccatc
    23581 aggataacag ctacccaccc tagcgtatct tccagaaaat gcagactcag aatagactca
    23641 ttctttgtct ttcccttacc aaccaccaga ctcgctaaca gattgatagt aatcgcaata
    23701 attcctaacc agagaatccc ctcatcattg actggttgcg gatgcaaaat cttcgtgaca
    23761 ttttccaaaa tgactagaac agagcctgtt acgagaatca cagctgttac caaggctcct
    23821 agcaggctaa accgcttata gcccaaggtg tactgattgt cttcttcacg attggagatt
    23881 gtttctagaa aagctgatat tccaattgca atcacatctc ccaagtcatg cacagagtca
    23941 gcaagaacag cgctagaacc aaatactcca cctgcaataa actcaacaat ggcataagtc
    24001 aaatttaaga aaaaagccac ccaaacagca tattttgcct tcatatttct cattcctttg
    24061 ttataatagg tttatgaaca ccttgttcat tatcattatc cactaaaact caaagaaagg
    24121 atagaagcaa aacgtcagct ttattcagtt ctgaacaatt tgccttaagt gtccatatga
    24181 ctaacattga ccgccgtatc agcaaaacca aaaaagccat ctatcaagct tttatacaac
    24241 ttttgaatgc taagggctac gaggccacta ctgttcagga tatcattgat ctcgcagatg
    24301 tgggaagatc caccttttac tgtcactatg aaagtaagga gcttcttctg gaccagctct
    24361 gccgctacct cttccatcat ctttttgaaa gagagcaagc catttcaacc gaggactacc
    24421 tcgcccacct ctttctccat tttcataaaa accaagacca tatcaccagt ctgctatttt
    24481 ccaaaaatga ctacttcctc cgtcaactcc ataaagagct agaacaccat gtctattccg
    24541 tgctagctga taatttaaaa gaagcccacc ctaatatgcc tacttcttac ctccaacact
    24601 tggtcgtgtc caactttatc gagacattga cctggtggct caaaaaaggt caagatttca
    24661 cagaccagga agttgtccaa ttttatctag accttctcat tcctaaaaat tgaatataga
    24721 gtaaagctca gttgtcttat ttctaggtta ctgagttttt tatcttttca acaacaaaag
    24781 aggacccgcc gatcctcttt ttcatactat aaatccttga ttatcaacta tatctgtttt
    24841 aatcgaaatc tcaaaacagc actttcaaac atcttttcct agttaggtaa atcagtattc
    24901 tgcttagctg ccttgctcca ttgataccaa ccaactagac tgttaatgag ataaattaga
    24961 tatttccctt gaatttgcag gctttctccc caccagagat agattgaaaa aacattggta
    25021 gccgcccaga atatccactg ttcacggtaa acagctgtca tgaggatttg ccctacccca
    25081 ttggttgcat ctgtgattga atcacgatag ggacgattgg caccaataga ctgataaatg
    25141 aagccaaagg ccaaccacca aagcacacta atggaaagat actttgtcca gcccttgccg
    25201 tccagtttac gcgcgacaaa ctcctgcttt tccttcttaa actgtgcctg ataaatccaa
    25261 actagaagtc caattggctg catgactgtg aagtaaagtg tcgtcagcac ctcaccataa
    25321 aagcctttct gtagggccaa aataaggtaa ataacagagt taatcaagcc aaaaagataa
    25381 ttacttgctc gaccttccga tacaaagatt acacagataa tccctgtcaa gctacaaatc
    25441 atcccaatcc agtcaacaat acgatgttcg taaaccaact ccagccagag aggaaaactt
    25501 cctaaaacca gcaaataaat ccactgggca aaactacgat gggcaaagag gtcatcccag
    25561 atagccttca tagttcctga aaatcctaaa tcagccatag ccgcaaccat acgacggtaa
    25621 ccacctgaca tttcacctag ggttgttttg atattttcaa ttttcttttg caaataagta
    25681 tgcatcattt ctccttttgt ttttaaagag ccgtgtctgg atagactttc ggacgcaacg
    25741 ctctattaga taatgaactg cctatacaca agatttctaa ccttagtcga catgagctga
    25801 aacctcttat ttgttaagta gttcacaaaa tattatacac ctattttatg aatagtcaac
    25861 tgtctttaca gtaaaatttt agaaaatcat gaaaattttc tctttctttc cattttaagt
    25921 gacattcagt cattctcaca tcaaaaaagc ccagacgaaa ctgtctgagc attcttttat
    25981 ctagtcgttt aaggaagttg agttcagtat gttt
//
LOCUS       DAVBNZ010000028        25528 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000028 DAVBNZ010000000
VERSION     DAVBNZ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25528
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.028"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            59..772
                     /locus_tag="VQ860_001200"
     CDS             59..772
                     /locus_tag="VQ860_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET3119628.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            786..1433
                     /locus_tag="VQ860_001201"
     CDS             786..1433
                     /locus_tag="VQ860_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119629.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            1571..2224
                     /locus_tag="VQ860_001202"
     CDS             1571..2224
                     /locus_tag="VQ860_001202"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET3119630.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTSWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            2234..2698
                     /locus_tag="VQ860_001203"
     CDS             2234..2698
                     /locus_tag="VQ860_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3119631.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            2711..3979
                     /locus_tag="VQ860_001204"
     CDS             2711..3979
                     /locus_tag="VQ860_001204"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET3119632.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            3993..4253
                     /locus_tag="VQ860_001205"
     CDS             3993..4253
                     /locus_tag="VQ860_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119633.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ860_001206"
     CDS             4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ860_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET3119634.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            5779..6747
                     /locus_tag="VQ860_001207"
     CDS             5779..6747
                     /locus_tag="VQ860_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET3119635.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            6763..7755
                     /locus_tag="VQ860_001208"
     CDS             6763..7755
                     /locus_tag="VQ860_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET3119636.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            7973..9016
                     /locus_tag="VQ860_001209"
     CDS             7973..9016
                     /locus_tag="VQ860_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET3119637.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ860_001210"
     CDS             9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ860_001210"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET3119638.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDCIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAIAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIVDKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            10829..11818
                     /locus_tag="VQ860_001211"
     CDS             10829..11818
                     /locus_tag="VQ860_001211"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET3119639.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ860_001212"
     CDS             complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ860_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET3119640.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETAGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(13455..15005)
                     /locus_tag="VQ860_001213"
     CDS             complement(13455..15005)
                     /locus_tag="VQ860_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET3119641.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(15021..15800)
                     /locus_tag="VQ860_001214"
     CDS             complement(15021..15800)
                     /locus_tag="VQ860_001214"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET3119642.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ860_001215"
     CDS             complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ860_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET3119643.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(16720..18228)
                     /locus_tag="VQ860_001216"
     CDS             complement(16720..18228)
                     /locus_tag="VQ860_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3119644.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTGKWKSVTVSYTKNTSRAR
                     KQAEREVLDKIDRLTTSFESQFSPELITTFGELKENWFQTWCVSVKPQTIQRELLVMK
                     RLGKIIGDDFLLDRITPLLMKKSLNKYLEIYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KFSPMTAVKLDISLEKRRKAKERHDSKFLEIHELHAFFDVLSQCRNANYYDLAIVLLL
                     TGIRISEAAFLPSDIDFEKGILHIDKALQYHCLKVEQFHFDTTKTLNSIREVALPEAA
                     SEAIKRTIQRNKEFDAYMEKHPCPAFTHSESVFRTEYGSPITSSTFRQILKRIEGKLL
                     TNCLSDYGFKWVKHVTPHSFRHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     INRSQENTVKALNQFVENHNFHFEELKSYTCKYSRIIEKFIETSDNSNKVEFSVDEFK
                     DLLHLSPRYSPKNIISNLLLKIKKDIVKYHPQFDIKIVKSSENQIRGFSIAW"
     gene            complement(18313..18546)
                     /locus_tag="VQ860_001217"
     CDS             complement(18313..18546)
                     /locus_tag="VQ860_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3119645.1"
                     /translation="MNIKYISVENSIAEWADKKGILKRWDGLNQYTLNRWIKEMRENR
                     TFSMYVINPTHKLVFINLEGFESFLRWKQKRTK"
     gene            complement(18816..19040)
                     /locus_tag="VQ860_001218"
     CDS             complement(18816..19040)
                     /locus_tag="VQ860_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3119646.1"
                     /translation="MLKRIRDLREDDDLTQEYIAKIVLNCTRSSYSKMEAGSRLISIN
                     DLIKLADFYKVSLDYLVGRVDNKEDHYSKK"
     gene            complement(19144..20973)
                     /locus_tag="VQ860_001219"
     CDS             complement(19144..20973)
                     /locus_tag="VQ860_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HET3119647.1"
                     /translation="MVITKHFAIHGKNYRSKLIKYILNPSKTKNLTLVSDFGMRNYLD
                     FPSYEELVKMYNDNFLSNDTLYEFRHDRREVNQRKIHSHHIIQSFSPDDHLTPEQINQ
                     IGYETVKELTGGRFRFIVATHMDKDHIHNHIILNSIDQNSDKKFLWDYKSERNLRMVS
                     DRLSKIAGAKIIENRYSHRQYEVYRKTNYKYEIKQRVYFLIENSKNFEDFKKKAKALH
                     LKIDFRHKHVTFFMTDSNMKQVVRDSKLSRKQPYNETYFKKKFVQREIINILEFLLPK
                     MKNMNELIQRAEFFGLKIIPKEKHVQFEFDEIKISEQELVKANRYSVSYFQNYFNNKN
                     ETVVLDNKNLVELYNEEKLIKEKELPTEEVVWKSYQDFKRNRDAVHEFEVELNLNQIE
                     EVVDDGIYIKVQFGIRQEGLIFVPNIQINMEEEKVKVFLRETSSYYVYHKDSTEKNRF
                     MKGKTLIRQFNLQYEPQYMYRRIPLSKIKEKIEQLDFLVSAENSQNAFEDITKDFIAQ
                     ISYLENMIDHVQNKIDDLSNLEEVLLNDATNSSSNLENSIQGKSSVDTIEKDLYIYKG
                     KIETLKEQHREAINLFEMFNKTIKKYKKKQNTKSIKENEIHLE"
     gene            complement(20960..21325)
                     /gene="mobC"
                     /locus_tag="VQ860_001220"
     CDS             complement(20960..21325)
                     /gene="mobC"
                     /locus_tag="VQ860_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HET3119648.1"
                     /translation="MEHRYRTNLKKVFLSDLELVKLNENISKSNCLSFSEYARRTLLD
                     PGMNFITIDTNSYQDLIFELKRIGNNINQIARSINYSNLITEVELNELRKGIEELIVE
                     VEKDFLIQSEKLRKFYGHH"
     gene            complement(21330..21686)
                     /locus_tag="VQ860_001221"
     CDS             complement(21330..21686)
                     /locus_tag="VQ860_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119649.1"
                     /translation="MKRDIRSIRKQFRLTETEEKQILDLMREKGEDNFSDFLRKSLLL
                     SDGQKQMEKWFNLWKKQKLEQISRDVHEVFIIAKTNHQVTHEHVSILLTCIQELIKEV
                     EKTGPLSEDFRNKYMR"
     gene            complement(21982..22272)
                     /locus_tag="VQ860_001222"
     CDS             complement(21982..22272)
                     /locus_tag="VQ860_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119650.1"
                     /translation="MNRKELYDDKLQLDYFSDSYLQFESDFYKYSALDIPLTFITDDI
                     LRTMAMSQKHYFKLNKSKSLDGRDHYFVFSIKMNKDSSGIRQYEYQRHCFNL"
     gene            complement(22262..22627)
                     /locus_tag="VQ860_001223"
     CDS             complement(22262..22627)
                     /locus_tag="VQ860_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000981955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119651.1"
                     /translation="MMNRSYLPFESARVYQDRGMAKWMGFFLSEHSSSLWAEKNKEDI
                     SISLSLEEKVLFVRQLYTNVFPATFVFKFSNQRKVVSGIVKEIGKEFISIKSDTGFLR
                     LKWEDILDIQIEGEELHES"
     gene            complement(22624..24039)
                     /locus_tag="VQ860_001224"
     CDS             complement(22624..24039)
                     /locus_tag="VQ860_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HET3119652.1"
                     /translation="MSWFDYSLEPQSDIAFIDMKSFYASVECVDRGLHPLKTSLCVMS
                     RADNSAGLILASSPMFKKVFGKSNVGRSYDLPFDVKTRKFSYYNARKQGLPTTIDYVR
                     YIEEWAKSTVIVPPRMDTYIAVNMEIQKIFQEFAAPDDIYPYSIDEGFIDLTSSLNYF
                     VPDKRISRKDKLDIISAAIQKKIWRKTGIYSTVGMSNANPLLAKLALDNEAKKTPTMR
                     ANWSYEDVEKKVWTIPKMTDFWGIGNRTEKRLHNLGIFSIKELAQANPDLIKKELGIM
                     GLELWFHANGIDESNVHKPYKPKSKGIGNSQVLPKDYIKQRDIEIILREMAEQVAVRL
                     RRSGKKATVVSIHLGYSKVEQKRSINTQMKIEPTNQTALLTNYVLKLFHTKYTSGAIR
                     NVAVNYSGLVDESFGLISLFDDIEKIEKEERLQSAIDAIRTEFGFTSLLKGNALDQAS
                     RTIARSKLIGGHSAGGLDGLK"
     gene            complement(24042..24725)
                     /locus_tag="VQ860_001225"
     CDS             complement(24042..24725)
                     /locus_tag="VQ860_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3119653.1"
                     /translation="MFSPTKLKEKRESQGLSQSQLASSLGISRASYFNWESGKTKPNQ
                     NNLSKLSEIFNVDPRYFESEFEIVETYLKLTKKNQKATLHYATELLNKQNAKVVEIPE
                     RFAYKVYEKLSAGTGTAYFDDGNYDTVYFNRQFDYDFASWVSGVSMEPTYKNGSVALI
                     KQTGFDYDGAIYAIDWDSQTFIKKVYREENGLRLVSLNRNYPDKFAPYDENPRIIGKI
                     VGNFMPLED"
     gene            complement(24953..>25528)
                     /locus_tag="VQ860_001226"
     CDS             complement(24953..>25528)
                     /locus_tag="VQ860_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3119654.1"
                     /translation="DSFRSQHPRYLELQQEYGKDSVEYTKDFAGKMVESLVTELSHLG
                     YNLLIEGTLRTIDVPKKTAQLLKSKGYEVQLALIATKPELSYLSTLIRYEELYSINPN
                     QARATSKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTTSAATVLH
                     DLLFGEWNQVEKEMLKSGEERLKDLTNRNGL"
BASE COUNT         7738 a         4760 c         4772 g         8258 t
ORIGIN      
        1 tatgaggtgc tttatgatat aatgttctta atgaattttc agaaaggaaa acctcaaatt
       61 gttctacaaa tttctactct tcgacctcga ccacactctt cttgattttg atgctgctga
      121 ggatgtggct ttgacccaac ttctaaaaga agaaggagtt gcggatattc aggcttataa
      181 agattattac gttcctatga acaaggctct ctggaaagac ttggagctga agaaaatcag
      241 taaacaagag ctggttaaca cgcgcttttc tcgtttattt tctcattttg gacaggaaaa
      301 agacggtagt tttcttgccc agcgttacca attttatctc gctcagcagg gacaaacact
      361 atcgggcgct catgatctct tggacagcct cattgagcgt gattataact tgtatgctgc
      421 gacaaatggc attactgcca ttcagacagg acgtttggct caatctggtc tagtacctta
      481 tttcaatcaa gtctttatct cagaacagtt gcaaactcaa aagccggatg ctctctttta
      541 tgaaaagatt ggccagcaaa ttgctggatt tagtaaagaa aagacgctga tgattggaga
      601 ttctctaacc gccgacattc aaggtggcaa taatgcgggg attgacacta tctggtataa
      661 tcctcatcac ctcgaaaatc acacacaagc ccagccgact tacgaagtct attcttacca
      721 agacttgctg gattgtttag ataaaaatat tcttgaaaag atcacatttt aaaggagatt
      781 agctaatgac tacaaaaaaa gctaatatta ctattgaaga gtacattgaa atgtctgaag
      841 ttgattttaa tgaagctgtt aattatgaat ttacatctga cacttgtcaa ttagcaaata
      901 gtatttatca atctcttttt aagttttttg ataagaaaaa tttctctggc gatttaattt
      961 ttacttggaa atctccatca ttagtcaaag aaggggatta tattgggaga agggattcac
     1021 aagtagataa tcttagagta ataggaaata tatttccgaa ttatcttact aatcgaaaat
     1081 atagcctcaa tatgaatcgt aatggctgta tgggagattt tcctcatgac ttttttgata
     1141 tatacctaga tcatgtagca aaatatgcct acgaacaaaa agttaataat attaaagagt
     1201 attatccttt aaaaagagcg attttacacc aagagaatgc attgtatttt cgattttttt
     1261 ctaattttga cgacttttta gaaaaaaatt atttaaagac tatatggcaa gtttctaaag
     1321 aaactccttt ttctgaaatg gattttaata tgtttaaaaa tatttcagaa aagataatct
     1381 tcgaaagagg tagtaaaatg cttaatgatt taaaaagtaa ttataaaaaa tagccagtct
     1441 ttataaactg tattcacgta ttcaaatcgt atatatagtc gatttattaa atctttagat
     1501 aaactgtaaa aagtggtttc catagccact ttttgctata atagaggcag taaaaatgaa
     1561 ggagtcggct atggaacact cgtcttggca tgctttgatt aaggcgcaat tacctgaggg
     1621 ttatttcggg aaaatcaatc agtttatgga gcaggtctat tctcagggga ttatttatcc
     1681 acccaaggaa aaggtttttc aggctctctt gacaacactg cttgaagaag ttaaggtggt
     1741 aattctaggg caagacccct atcacggacc aggtcaagcg cagggcttga gtttttctgt
     1801 acctgactct atcccagctc caccatcctt gcaaaatatc ttgaaagaat tgtcagatga
     1861 tatcggagtt aagaaatctc atgatttgac atcttgggct gagcaaggag tcttgcttct
     1921 taatgcttgt ttgactgttc ctgctggaca ggccaatggt catgctggtc aaatctggga
     1981 gccttttact gatgctgtga ttcaggtggt caatcatcta gatagaccag tcgtttttgt
     2041 actctgggga gcttatgcac gtaagaagaa ggcattagtt accaatcctc atcacttgat
     2101 tatcgaatca gcccatccaa gtcctttgtc ggtttataga ggattttggg gttccaagcc
     2161 cttttccaag gccaatgcat tcttaaaaga gacaggacaa gagccaatcg attggcttag
     2221 ataaggagaa aatatgcctc agttagcgac gatttgctac attgataatg ggaaagaact
     2281 gctcatgctc catcgtaata agaaacccaa tgatgtccat gaagggaaat ggattggtgt
     2341 gggtggtaag ctagagagag gagagacgcc ccaggaatgc gcggcgcgtg aaatccttga
     2401 agaaacaggg ctcaaagcca agccagttct aaaaggtgtc atcacttttc ctgaatttac
     2461 accagattta gactggtaca cctatgtttt taaggtgacg gagtttgagg gcgacttgat
     2521 tgactgcaat gaggggacgc tagaatgggt tccctatgat gaggttttga gcaagccgac
     2581 ttgggaaggt gaccacacct ttgttgagtg gcttttagag gataaaccct tcttttcagc
     2641 caagtttgtt tatgatgggg ataaattgtt ggatacccaa gttgatttct atgaataaag
     2701 gagaaagcag atgctactaa tcaaaaatgg tcgtgtaatg gatcccaagt ctggtttgga
     2761 tcaagtttgt gatgtcttag ttcaagatgg gaaaattatc aaaattgcgc ctgagatcac
     2821 ggaagaagga gcagaaacga ttgatgctac tggtcttgtg gttgctcctg gtttggtcga
     2881 tattcatgtg catttccgtg aacctggtca aacacataaa gaagacattc atactggtgc
     2941 cctggcagcc gctgcaggtg gttttactac tgtcgtcatg atggctaata ccagtccaac
     3001 catttcagac gtggagactt tgcaagcagt tctccagtca gctgccaaag agaagattaa
     3061 tgtcaagaca gttgcgacca ttactaaaaa ctttaatggt aaaaacttga ctgactttaa
     3121 ggcgctctta gaagctggtg cggctggttt ctctgatgac ggtattccgc ttgagagcag
     3181 taagattgtc aaggaagcca tggaggaagc caaaaaactc aataccttta tcagccttca
     3241 tgaggaagat ccaggtttga acggtgttct tggctttaat gaaaatattg ctagagaaca
     3301 tttccatatc tgcggtgcta ctggggtggc tgagtacgct atgatggcgc gtgatgtcat
     3361 gattgcctat gcaactaaag cccatgttca catccagcat ttgtctaagg aagaaagtgt
     3421 taaagtagtg gagtttgctc aggggttagg tgcagaagtc acagcagaag tagcgccaca
     3481 gcatttctct aagacagaag cacttttttt aacacaaggt agcaatgcta agatgaatcc
     3541 accgcttcgt ttggaatcag accgtcgtgc cgttatcgaa ggtctcaaat caggtgtcat
     3601 cacagttatt gcgactgacc acgcccctca tcatgtagat gaaaaaaatg ttgaggatat
     3661 taccaaagcg ccatctggta tgactggctt agaaacatcc ctgtctctca gcttgaccta
     3721 tttagtagaa gctggtgagt tgagcttgat ggaattactt gaaaaaatga catacaaccc
     3781 agccaagctt tacaactttg aagcaggtta cttggctgag aatggtccag cagatatcac
     3841 tatttttgat gccaaggctg accgccttgt ggactcccat tttgcttcca aagcagctaa
     3901 ttcaccattc atcggtgaaa ccttaaaagg gcaggttaaa tataccatct gtaagggaca
     3961 aatcgtctat caagcttgat aggagttaga atatgaatta ttttcgaaaa cgtagggaga
     4021 gacaagcgaa atctaatagt ggaatttact gtcccgcagc taatcgttcc aaaattcaat
     4081 atgaaactaa agaaaaagct gaccatgcgg ttcaatatga taacggaggt ttagttagaa
     4141 gctattattg tcgtacatgt gcgtgttggc atactacttc aaaatctaat aaacctccgc
     4201 taagtttgaa aaactatggt ctgaaactct ttggtttaga taaatcagaa tagaaagaga
     4261 agtatgtata agacaaagtg tttacgagag aagttagtat tatttttaaa aattttcttc
     4321 ccaatcctga tttaccaatt tgccaattat tctgcctctt ttgttgatac tgcaatgaca
     4381 ggtcaataca acactatgga cttggctggt gtatctatgg caaccagtat ctggaatcct
     4441 ttctttacat ttctaacagg gattgtgtca gccttggtgc ctatcattgg tcaccatctt
     4501 ggtcgaggaa aaaaggaaga agttgcgtct gatttttacc aatttattta tttggccttg
     4561 ggcctatctg tggtattgct ggggatggta ctttttttgg caccaacaat cttgaatcat
     4621 attgggttag aagcagcagt agcggcagta gcggttcgct atctttggtt tttatctatc
     4681 gggattatcc ccttgttgct ctttagcgtc attcgttcct tgctggattc gctgggcttg
     4741 accaaactgt ccatgtacct catgcttttg ttactccctc tcaatagcgg atttaactat
     4801 ctcttgattt acggtgcctt tggtgttcca gaactgggag gggctggtgc tggtttagga
     4861 acatccttgg cctactgggt cttgcttggg atttctgttc tggttttatt taaacaggag
     4921 aagctcaaag ccttacacct tgagaaacga attccactta atatggataa aattaaggaa
     4981 ggagttcgtt taggtctgcc tattggggga actgtcttcg cggaagtggc tatcttttca
     5041 gtggttggct tgattatggc taagttttcg tccttgatta tagctagtca ccagtcagct
     5101 atgaactttt caagtcttat gtacgccttt cctatgagta tctcatcggc tatggctatt
     5161 gtcgtttcct atgaagtggg agccaagcga tttgatgatg cgaaaaccta tattggtcta
     5221 ggaagatgga ctgccctcat ttttgcggcc ttcaccttaa ccttccttta catttttagg
     5281 ggaaatgtgg ccagtcttta tggtaacgac ccaaaattta tcgatttgac agtgcgtttt
     5341 ttaacttata gtcttttctt ccagttagca gatacctttg cggcgccgct tcagggaatt
     5401 ttgcgggggt ataaggatac agttattcct ttttaccttg gtttgcttgg ttattggggc
     5461 gtagcaatcc ctgtggctac gctatttgat tctctaacag attttggagc ttattcttac
     5521 tggatcggct tgattattag tttgattgtg agtggggcgc tctaccgttg gcgtttaact
     5581 gtgattatga agagatttga atctttagca aaatccaaac gctaaaaagt ttgtgaaaaa
     5641 atattcttga taagaaaatc ccttgttttc acggggtttt cttttttatt ttgtgaaatt
     5701 tcttttagaa aaactttgac agtatttgcc aaaaacggta aaatagtaag gtaagaagaa
     5761 agttagaaag gcaagaagat gtcaacttta gataaaaatc ttttgctaga aatgttccgt
     5821 aagatggaag aaatccgtcg catggactta aaaattgcac aattagtaaa gaaagggaaa
     5881 gtgccaggaa tgacgcactt ttctgttggt gaagaggcag ctaacgtggg ggctatgtta
     5941 gctctcaatc cagatgatct gattacctca aaccaccgtg gacacgggca agctattgct
     6001 aaagggattg acctcaacgg aatgatggct gaaatccttg gtaaatacac tggaacctgt
     6061 aaagggaaag gtggatctat gcatatcgct gaccttgatg ctgggaacct tggtgccaat
     6121 ggtattgtag gtggtggtat ggggatcgct gtcggtgcag ccctcagtca gcaaatgcaa
     6181 aataccggta aaatcgttgt ctgcttcttt ggagatggtg cgaccaatga aggtgttttc
     6241 cacgaagcag tgaacatggc ttctatctgg aacctgccag tcattttcta ttgcattaac
     6301 aacggttacg gtatctctgc ggatatcaag aaaatgacca atatagaaca tatccatcaa
     6361 cgtagcgccg cttatggaat tcctggaatg ttcatcgaag atggtaacaa tgtcatcgat
     6421 gtctatgaag gatttcagaa agctgtggac catgttcgca gtggcaatgg tccagtcttg
     6481 attgaaagtg taacttatcg ctggctcggt cactcatcat ctgaccctgg taaatatcgt
     6541 acgcgtgaag aagtggaatt gtggaaacaa aaagatccaa tcgaaaacct ccgcaattac
     6601 cttattgaaa ataacattgc aagtgccgaa gaattggaag aaatccaagc gcaagtaaag
     6661 gaagcagtag aagcttctgt taaatttgca gaggaaagcc cattcccacc gcttgaatca
     6721 gcctttgaag atatttacgc agactaagga gaaagagata aaatggaaac aaaaacaatg
     6781 tccttccgtg acaccattat ccttgctatg tctgaggaaa tgcgtcgcga tgaaaatgtg
     6841 ttcttgatgg gagaagacgt cggtgtcttc ggaggagact tcggtacttc tgttggaatg
     6901 cttgaagaat ttggtccaga acgcgtccgt gactgtccga tttctgaagc tgccatctct
     6961 ggagcagcag caggagcagc catgacagga cttcgtccaa tcgtcgatat gaccttcatg
     7021 gacttctctg ttattgccat ggacaatatc gtcaaccaag ctgctaaaac acgttacatg
     7081 tttggtggta aaggtcaggt tccaatgact gttcgttgtg cagctggtaa cggagttggc
     7141 tctgccgccc agcactcaca atctctagag tcttggttta ctcacattcc aggacttaag
     7201 gttgtggcac ctggaacacc tgcggacatg aaaggcctgc ttaagtcttc tatccgtgat
     7261 aaaaacccag ttattatact tgagtacaag tcagaattta accaaaaagg ggaagtgcca
     7321 gttgatccag actacacaat tccacttggg gttggtgaaa tcaaacgcca aggaacggat
     7381 gtaacagttg ttacttatgg aaaaatgctt cgccgtgtgg ttcaagctgc tgaagaatta
     7441 gcagaagaag gaatttcagt tgaaattgtt gacccacgta cccttgttcc gcttgataag
     7501 gatatcatca taaactcagt gaagaagact ggtaaggttg ttctggtcaa cgatgcccac
     7561 aaaacaagtg gctatatcgg tgaaatttca gctattattt cagaatcaga agcatttgac
     7621 tatctagatg caccaattcg ccgttgtgca ggagaagatg tgccgatgcc ttatgcacaa
     7681 aacctagaaa atgcaatgat tccaacagtt gaaagtatca aagatgcaat ccgaaaaact
     7741 tataacaaag aatagagtta cataagataa gttatgtaaa taaaataaag ctgacgagaa
     7801 actttgtatc ttttaggtgc agagctcttc gtcattaata tcttagatta gagcacgggc
     7861 taaaagctcg gaaaaaagat aaatctcctt ggcttcatcg aagccatcgt cgatttccta
     7921 tttttcagtc gcttttgacg ccctttgtat cataaataga attggagagg tcatggctga
     7981 tgacaagcta agagcgactc ctgcagctag aaagttagcg gatgatttag ggataaacct
     8041 ctacgacgtt tctggctcag gtgcaaacgg tcgtgtccac aaagaagacg tggaaactta
     8101 taaagacaca aacgtggttc gcatttcgcc acttgcaaaa cgaattgccc tcgaacataa
     8161 cattgcttgg caggaaatcc aaggaaccgg tcatcgtggt aaaatcatga agaaggatgt
     8221 tttggccctg cttcctgaaa atatcgaaaa cgatagcatc aaatctcctg ctcagattga
     8281 aaaagtggaa gaagtccctg ataacgtaac accatatggt gaaatcgagc gtattccaat
     8341 gacaccaatg cgtaaggtta ttgcccaacg catggttgaa tcttacttga ctgcgccaac
     8401 cttcaccctc aactatgaag ttgatatgac tgaaatgttg gctcttcgta agaaggttct
     8461 tgagccaatc atggaagcaa ctgggaagaa gactactgta acagaccttc tttcgcttgc
     8521 agttgttaag actcttatga aacacccata catcaacgct tcattgacag aagatggcaa
     8581 gactattatc actcacaact atgtcaatct tgccatggca gttgggatgg ataatggatt
     8641 gatgacacct gttgtttaca atgctgagaa aatgagtctt tcagaactgg ttgtagcctt
     8701 taaggatgtt attggccgta ccttggatgg taaattggct ccaagtgagt tacaaaattc
     8761 aacattcaca atcagtaatt tgggaatgtt tggtgttcag tcctttggtc cgattattaa
     8821 ccaacccaac tcagctatcc ttggtgtcag ttcgacaatc gagaagccag ttgtcgtcaa
     8881 tggtgaaatt gtgattcgcc caatcatgag tttaggatta accattgacc accgtgtcgt
     8941 agatggtatg gctggtgcta agtttatgaa ggacttgaaa gagttgattg aaacgccaat
     9001 ctcaatgtta atttaagagc aagagtattc atttttaaga tatagataaa ggaaggaaga
     9061 catggcctta gaagtaatta tgccaaaagc cggcgtggat atgacagaag gacaaatcgt
     9121 ccaatggaat aaaaaagtcg gagaatttgt aaaagaagga gaaatccttt tggaaatcat
     9181 gactgataaa gtcagcatgg aattggaagc cgaagaagat gggtacttga ttgccattct
     9241 caaaggagat ggtgaaactg tccctgtaac ggaagttatc ggttaccttg gtgaagaaag
     9301 ggaaaacatc ccaacagctg gagcagcatc gccagaagct agctctgtac ctgtagcaag
     9361 tacctcaaac gatgatgata agagcgatga tgcttttgat atcgttgtga ttggtggagg
     9421 tcctgctggt tatgttgcag ccattaaagc tgcccaattc ggcggtaagg ttgcccttgt
     9481 tgagaaatct gaacttggtg gaacctgctt aaaccgtgga tgtattccaa ccaagaccta
     9541 ccttcataac gctgaaatta ttgaaaatat cggtcatgct gcaaatcgtg gtatcgtgat
     9601 tgaaaatcct aacttcactg ttgatatgga aaaactttta gaaactaaat ctaaagttgt
     9661 taatactctt gttggtggtg ttgcaggact tcttcgtagc tacggagtta ctgttcataa
     9721 aggaattggt acaatcacta aagacaagaa cgtcttggta aatggctctg aattgcttga
     9781 aaccaagaaa atcattcttg ctggtggttc aaaagtcagc aagatcaacg tccctggtat
     9841 ggaatctcca cttgtcatga ctagtgatga cattcttgaa atgaacgaag tgccagaaag
     9901 ccttgttatc atcggtggtg gagttgtcgg tatcgaactc ggtcaggcct tcatgacatt
     9961 tggttcaaaa gtgactgtta tcgaaatgat ggactgtata gttccagcta tggatgcgga
    10021 agtttctaag aaccttcgct tgatccttga gcgtaaagga atgaccatct tgactggtac
    10081 taaactgcaa gaaatcattg aggaaaatgg tcaacttcgt atcaaggttg aaggaaaaga
    10141 cgatatcatc gcaagcaaag ctcttctttc aattggtcgt atgccagacc ttgaaggtat
    10201 tggagaggtt gagtttgaat tggatcgtgg ttgtatcaag gtcaatgaat acatggaaac
    10261 ttcagttcca ggcatttatg caccaggtga catcaacggt actaagatgt tggctcacgc
    10321 agctttccgc atgggtgaag tttccgctga aaatgccctt aaaggaaatc atgcaattgc
    10381 caaattgaat ttgactcctg cagccatcta cactctccct gaagtagcag cagtaggttt
    10441 gacagaagaa caagcccgtg agaaatacga tgttgccatc ggtaagttta actttgctgc
    10501 taacggtcgt gctattgcat ctgacgctgc tcaaggtttc gtaaaagtta tcgttgataa
    10561 gaaatacgga gaaatccttg gtgtacacat tattggtcct gcagccgcag aattaataaa
    10621 cgaagcatca agcatcatcg aaatggaaat cactgttgag gaaatgctga agaccatcca
    10681 cgggcaccca acttactctg aagtgatgta cgaagcgttt gcagatgttc taggaatggc
    10741 catccattca cctaagaaaa aataaaacga agatagatta gactggaagg ttatttccag
    10801 tttctatcat ataaagtaaa gggatatcat gaaatacatt atcaatcatt caaatgacac
    10861 tgcttttaat attgccttgg aagaatacgc ctttaaacac cttttggatg aggatcaaat
    10921 cttcctactt tggattaaca agccatctat cattgttggt cgtcaccaga acactatcga
    10981 agaaatcaac cgtgattatg ttcgtgaaaa tggtattgag gtagttcgcc gtattagtgg
    11041 tggtggagct gtttaccacg atttaaataa cctcaactac acgatcatct ccaaagaaga
    11101 tgaaaataag gcatttgact tcaagagctt ctcaactccg gttatcaata ccctggctca
    11161 acttggggtt aaagctgagt tcacaggtcg taatgacctt gagattgatg gtaagaagtt
    11221 ctgtggcaat gcccaagcct atatcaacgg ccgtatcatg caccacggtt gcttgctctt
    11281 tgacgttgat ttgtcagtcc tcgcaaatgc ccttaaggtt tcaaaagata aatttgaatc
    11341 aaaaggtgtg aaatccgtcc gtgcccgtgt aaccaatatt atcaatgaat taccaaaaaa
    11401 aatcacagtc gaaaaattcc gtgatttact cttggaatac atgaaaaaag agtacccaga
    11461 gatgactgaa tacgtctttt cagaagaaga attggccgaa atcaatcgca tcaaggatac
    11521 taagtttgga acttgggact ggaactatgg taaatcacct gaatttaacg tccgtcgtgg
    11581 aaccaaattc actagtggta aggttgaagt ctttgctaac gttactgaat caaaaatcca
    11641 agacatcaag atttatggtg acttctttgg tattgaagac gttgctgcag tagaagatgt
    11701 ccttcgtggg gtgaaatacg aacgcgaaga tgttcttaag gcgctaaaaa ccattgatat
    11761 cacacgctac ttcgctggta ttagccgtga agaaatcgct gaagcggtag ttggataaat
    11821 caaaaagaag ttggccaact aaccaacttc tttttttgat atttatttac ataatttaaa
    11881 atacgtaaaa ttataaacta tctagagcat tcttttgttc atcattaaca atatgggtat
    11941 agaggtcagt gacttgtgtg ctggcatgtc ctagttggtg actgactaaa acttgtgatt
    12001 tagtcgcatc atagagccta gttgctagcg tatggcgcag tttatggggt gttacacgca
    12061 ctttaaaatc ctctgagtat ttagcaacca ttttctcaac gctagaagca tcgatacgat
    12121 taggaacacc tctgtagaga gttaaaaaaa gggctgtatc tgttttttcc gttttatagc
    12181 gttgattccg aatggccaga taattctcta aataaggttt agcaaaagca gcgacattga
    12241 ctgagtcacg tttgccacct tttcgagtaa catcaataac catcattttt agattgagat
    12301 ctcttagatc tagattaaca gcttcagata agcgaacacc agatgccaag agaagggcaa
    12361 taatggctaa atctcgttct ttatttttgt tgaatgatga gagagctcga tttgaaagct
    12421 gttgtgggtg ctcttgatcg atataagtta gaaaacctgc tgtttcatca cctagaaaga
    12481 gtttttgctt gatattttca gctctggcag caagggtttc tttctttttc ttggttgaaa
    12541 cttttttcat tacattacga tagaaataag gttccccctg atcattttca acctcctcgg
    12601 ttagatactt gtaaagacta gaaagtgctg ataaggttcg attgatagtt gtctgtgaaa
    12661 caccttgttt tgttgtatta gcattcagca agggacgttc acgtagataa aggataaagg
    12721 attccatgtc tttcttagac atattttcca aaactgataa aggaatatcg gatattttat
    12781 cagcgtttga aataccagac tccaaaaccc agctgaaaaa tcggtcatat tccttaaggt
    12841 attcgtacag ggttgtaaaa ctgtagggca cagccagttt agattggtag tattccagaa
    12901 cataccaggg catgagttgt tttagtttgt cgattcgttc cagtaaaatc tcacgtttca
    12961 tgtattttct ccataattaa gtatactagt agtatagcat agacttgtat atttttcaag
    13021 aaaattatag tttttcagaa agatgttata ggagtttttc aaagtgataa aaagacttag
    13081 acctacaaac aaaacagaat aaggaaaata ataaaaatct cacccactaa acttctgtta
    13141 atactacata gctagaaatt gatttgattg tcctgattgt tttatcctat ttctatttca
    13201 tttcactata taattgctat tgttttcttt ttcatgattt taatcttact gtacagattt
    13261 gatacagtaa actcctttct agctttatgc tttatcattt ctaacttaat tatagtctta
    13321 tttttaataa agttcaatta tttatatgta aaattcctca tcagtaaaaa ataaccgatc
    13381 tcatttctga gaatcggttt tctaaataaa tcaaaccgat catttacata acataaatta
    13441 tgtaaatgat catactacaa caacaaatct ttgacttttc caatttcact ttttggaata
    13501 accaggtgaa tcatatcacc cagatacatt ctggttgagc cgttaactgt ttggctcttg
    13561 ccattatgga cttgagttgt gatgaggacg ttgtgtggta agttgagttc atgaacttgt
    13621 ttcccagcaa ttttatcaga aactggtatt tcgataagtg taacttctcc ttcgctagat
    13681 acttcttctg gaagcatttt ttccagcatg gcttcataga ctggcgtacc tttgagcaaa
    13741 tccatgataa tataagaaac aagagtgaca agaccaagtg gcataaggtt gcgaatatct
    13801 cctaccatct cagttacgag gatcatagcg gttaagggag cttttgatat ggctccaaaa
    13861 tagccactca ttcctagaat gacaaatata gggaattgct cttgactgac aagtccaaga
    13921 ttgacacaga taacaccaac taaggcacca agcaaagaac caagagctaa aatggggagg
    13981 aaaattcctc ctggcagtcc acttccatag ctaatcatac tccaaataaa gcggattaaa
    14041 aagtaagcta ataaaacttg gaaactaaaa ttttgttcag ttaaagaaag gacaagctga
    14101 tttccgccac caatgatttg aggtaagaag attccgactg gtatgataag gataaaagcc
    14161 aagatgggat aataagccct atccaaatgg attttttgac caatcaagtc ataaactctt
    14221 ccaacgttta atacagcttt ctcatagaga aaacctgaaa atccaaggaa aattcccatg
    14281 acgagatata tccaatactg gtctagggtc atgggaggaa tgttatctgg catatccaat
    14341 actggtgtca aaccgaacat gagtagagac acaaagtttg ctacgatgct ggctgctaga
    14401 gttgagaccc agaaaaagcg cgaaaaatgg tgatagactt cttctacaac aaagagaagt
    14461 gctgcaatag gagcattaaa ggctgcggct aaacctgctg cagctccact ggcaatcaag
    14521 gaacgttcct ctactggact ggatttgagc cacttggcaa ttcctttacc accaactgct
    14581 ccaagttgaa tgctgggtcc ctctcgaccc agcatgagtc cactggcaat agcaagaata
    14641 cctagcacat attttttcca aagaatgccc caccagttga gggacatgag gcctttcagt
    14701 tcggcttcga cttgaggaat tcctgagcct ttaatatctt tttctgaccg tgttagtttg
    14761 gcactgagcc aacagatgag tatataaaac aaaaccagta caaaaagatt gcgcactaag
    14821 tacccttgat cttgataaac tccttgtatc aggtggaagc ccttttcaat taagaaacga
    14881 aaggatccga cgataattcc aacgatgagg ccgacaatga ttcctcgacc aacttgggat
    14941 agtatagtgc tggatgcaaa ggcgaattct ttcttagaac ggactatttc cgactgttcc
    15001 tccatggtat ttcctttcaa ttaactttct tttttaccta aaaccagtga tttaacgggt
    15061 tcaaagctgg ttcggtgaat tggggtaact cctagttttg tgaggccttc cagatgttta
    15121 gctgtgccat atcctgcatt agtagcgaaa tcatagccag agaactgctg atcgtattct
    15181 ttcatcaatt catcacgtgt taccttggct actatagatg ctgctgcgat agagagggag
    15241 ttggcatctc ctttgataat ggaggtttgt gaaatgggca agtccagttt catggcatca
    15301 atcaaaaggt gctctggttg agggctgagc tgggagattg cttcttgcat ggctagtttg
    15361 gttgcttcat agatgttgac ttggtcgatg acctgattat ctatgatacc aattccaatc
    15421 gacaaggctt ggtcttgaac ggcttggaaa atctccagat gtttcttttt aggaattttc
    15481 ttgctgtcgt tgagaccttt aatcttacaa tttttaggta aaataacggc cgcagcgact
    15541 acaggaccag caagaggacc acgaccaacc tcatcaatac ctgcaattaa ggtcaatcct
    15601 tgcttataaa gttctttttc ataagaaagc atggattcca agcgcaaatt ttcatctaat
    15661 tcagcttgaa tggctctttt acgcttgctg atttcctttt gaactcctga gcgattatcc
    15721 ttttcaagct ctaaaaaaat agggctttct aactccttga ctgtcacaag gagttctttg
    15781 atttctttaa tcgttgccat cgaggtcttc caatgtatct aaggtatagt taccgagttt
    15841 gccatcacgg acttccttca cgaagagact gtaaaaacgg tcatagtcat cacggaaacc
    15901 gagggcgcgg gtcatatcca taataatcac aggcgcttct tcttcaattt tcatttgttt
    15961 gaagcgttca gccagctttt ctggataatg ttctttgaaa taattgatac caaaaatggt
    16021 aacctcatcc ataggaagca actgatcctt gatagctcca gtcaatgcca acttaagtgc
    16081 aacagtttca tcctcaaact taggccagag aatccccggt gtatccaaga tttccagatc
    16141 tttattggtt ttaagccatt gttgaccttt tgtgacccct ggcttgtttc caacaacagc
    16201 aatcttttta ccagccaaac ggttcatcag agttgattta ccagcgtttg gaatcccaat
    16261 aatcatggta cgcaaggttt caatctgaat cccacgttct ttctggcgag caatcttatc
    16321 agccatgagc ttcttggccg catctgttac aacttttaca gtcacttgct ctttggagtt
    16381 gatagctagc gtctggattc cttgtgattc aaaatactga cgccattcct tggtcattgc
    16441 tggatcagcc aagtcggcct tgtttaaaat caagagtttt ggtttatcac caacaatctt
    16501 ggtcaacata ggattttgac tagatagagg caagcgtgca tctactaaaa tcgtcacaaa
    16561 atcaacaaat tttaaatttt cctgcacctg tcgacgcgct ttagacatgt gaccaggaaa
    16621 ccattgaata gtagccattg agtttttttc ctttcatagc aagggtttag agcccctatt
    16681 ttattttact attgtctaaa caccaagcga acaccaaaac taccatgcaa tggaaaaacc
    16741 tctgatttga ttctcacttg atttcacaat ctttatatca aactgtgggt ggtatttgac
    16801 aatatctttt ttgattttta atagtaaatt cgaaataata tttttaggtg agtaacgtgg
    16861 actaagatgt aacaagtctt tgaactcatc gacactaaat tctactttat tgctattatc
    16921 actagtttca atgaattttt caattattct ggaatattta caggtataac ttttcaattc
    16981 ttcaaaatgg aaattgtgat tttctacaaa ttgatttaag gcttttacag tattttcttg
    17041 tgaacgattt atattatgtg tatagcccat tgttgtctca aagttagcgt gtcctactct
    17101 agtcataata tctttcactg ctatgtgcat ctcattactt tgaaggtaac taatatgcat
    17161 atgcctaaac gaatggggag taacatgttt tacccactta aaaccatagt cacttaaaca
    17221 atttgtcaat aattttcctt ctattcgttt caaaatttga cgaaaagtgc ttgatgttat
    17281 tggagagccg tattctgttc taaatacact ttcagaatgt gtaaaagcag gacagggatg
    17341 tttctccata taagcatcaa actctttatt tctctgtatt gtccttttaa tagcttcgct
    17401 tgcagcttca ggcaaagcta cttctctaat tgaattgagt gttttagttg tatcaaagtg
    17461 aaattgttca acttttaaac aatgatattg aagtgcctta tcaatatgca agattccttt
    17521 ttcaaaatca atatctgatg gtaaaaatgc tgcttcacta attcgaatac ctgtaagcaa
    17581 caatactata gcaagatcat aatagtttgc atttctgcat tggcttaata catcaaaaaa
    17641 tgcgtgtaat tcatggattt ctagaaattt agaatcatgt ctttcttttg ctttacgcct
    17701 tttctctagt gaaatatcta gttttaccgc agtcatagga gagaacttaa tgacattata
    17761 taacacacca tgattaaaaa tcttattaca agtacttttt atatgagtca ttgttgaagg
    17821 tgatgcatca tatatttcta aatatttatt gagacttttt ttcatcagaa gtggagtaat
    17881 cctgtctaat aaaaaatcat ctcctataat tttcccaaga cgcttcatca ccagtagttc
    17941 tctctgaatt gtttgtggtt taacagagac acaccaagtc tgaaaccaat tttcttttaa
    18001 ctctccaaat gttgtaatca gttcagggct aaactgactt tcaaatgaag tagttagtct
    18061 atctatctta tcaagaacct ctctttcagc ttgtttcctc gccctactag tattcttagt
    18121 ataacttaca gttactgatt tccactttcc tgttagtgga tctttgtact tttcaaccac
    18181 ttgatataag ggttgccctt ttgaatttgt tttagttaca taatacataa tttaattcct
    18241 cttaactctt aaaaagaaat aaatcattgt tgtatagaat aaataactac cctatattat
    18301 accatgactt ccttattttg tccgcttttg cttccatctt aagaaacttt caaatccttc
    18361 tagattaatg aaaacaagtt tatgggttgg gttaattaca tacatggaaa atgttctgtt
    18421 ttctcgcatt tctttaatcc atctgttcaa tgtatattga tttaaaccat cccatctttt
    18481 tagaattcct ttcttatcgg cccattctgc aatggaattt tcgacagata tatattttat
    18541 attcatgtca tcatccttcc taaaaaatat tttcacctcc atggcatgac tgatgaagtc
    18601 atcataagaa tttcacttgc tgctctttta cggtggcagc ctgaacggtc agaagtatca
    18661 ttgtatatca tttgtatcat ggcatataaa gtatcgctct attttattga tggttttaat
    18721 atcgctctta tcatggcgag ccattcaaaa ctgctccaca aatgaggaaa gtaccatttt
    18781 ggactattca attgtcaatg tgctttctta acctactact ttttggagta atggtcttct
    18841 ttattatcca ctcgacctac aaggtagtct agactcacct tataaaaatc tgcaagtttg
    18901 ataaggtcat ttatagagat tagcctgcta ccagcttcca ttttagaata agatgatctt
    18961 gtacaattca aaacgatttt cgcaatatat tcttgtgtca aatcatcatc ttcacgtaaa
    19021 tctctaatcc ttttcaacat ttgttgtctc ctaaaacaag tataatatag ttattttctt
    19081 atttttaaat atgtgacaaa ttggcacatg aaactattct atatatactt tttaggaaac
    19141 tgtttactct aaatgtatct cattttcctt aatagatttc gtattttgtt ttttcttata
    19201 tttctttatt gttttattaa acatttcaaa taaatttatt gcttctctat gttgttcctt
    19261 cagtgtttca atctttcctt tatatatgta taaatccttc tctattgtat ctactgaact
    19321 tttaccttga atactatttt ctaaattgct agaactattt gtcgcatcat tcaacaatac
    19381 ttcttctaaa ttactcaaat catcaatttt attttgaacg tggtcaatca tattctctag
    19441 atatgatatt tgggcaatga aatccttggt tatatcttca aaagcattct gactattttc
    19501 tgcagataca agaaaatcta attgttctat tttttcttta attttgctaa gaggaattct
    19561 tctatacata tactgcggtt catactgaag attaaattgc ctaatcaaag ttttaccttt
    19621 cataaagcga tttttttctg ttgaatcttt atgatataca tagtaagaac tagtttctct
    19681 gagaaatact ttaacttttt cttcttccat attgatttga atatttggta caaaaataag
    19741 tccttcttgt cggataccaa actgtacctt aatgtaaatt ccatcgtcta ctacttcttc
    19801 tatttgatta agattcaact ctacttcaaa ctcatgaact gcatccctat ttctcttgaa
    19861 atcttgatag gatttccata ccacctcttc tgtcggcaac tctttttctt taattagctt
    19921 ttcttcattg taaagttcaa ctaaattttt attatctaag acaacagttt catttttgtt
    19981 attaaaatag ttttgaaaat aactaacact ataccgatta gcttttacca attcctgctc
    20041 tgaaatctta atctcatcaa attcaaattg aacatgtttt tctttcggaa ttatttttaa
    20101 tccaaaaaat tctgctcgtt gaatcaattc attcatattc ttcattttcg gaagtaaaaa
    20161 ttctaagata tttatgattt ccctttgaac aaactttttc ttaaaataag tttcattata
    20221 aggttgtttt ctactcaatt tactatcacg tacgacttgt ttcatatttg aatcagtcat
    20281 aaaaaaagta acatgcttgt gtctaaaatc aattttcaaa tgtaaagctt ttgctttttt
    20341 cttgaaatct tcaaaatttt tcgagttctc gattagaaaa tatactcgtt gttttatttc
    20401 atatttgtaa tttgttttgc gataaacttc atactgacga tgcgaataac gattttctat
    20461 aatttttgcc cctgcaattt ttgaaagacg atcagaaacc attcgtagat tacgttctga
    20521 cttataatcc catagaaact ttttatcaga attctgatca attgaattta ggatgatgtg
    20581 attgtggata tgatctttat ccatatgagt tgctacgata aaacgaaatc tacctcctgt
    20641 caactcttta actgtctcat aaccaatctg attgatttgt tcgggagtga ggtggtcatc
    20701 tggagaaaag gactgaatga tgtgatgaga atgaattttt cgttgattta cttctcgcct
    20761 atcatgacga aattcataaa gagtatcatt acttaaaaaa ttatcattgt acatcttcac
    20821 tagttcttca taactaggaa aatctaaata atttctcatt ccaaaatctg aaactagtgt
    20881 taggtttttt gttttacttg gattcaaaat atatttgatt agtttactac gataattttt
    20941 tccatgaatc gcaaagtgtt tagtgatgac cataaaattt cctcaatttt tcagattgaa
    21001 taagaaaatc tttctccact tctactatta actcttctat accttttctc aactcattta
    21061 attcaacttc cgttattaaa ttagaataat ttatgctcct agctatttga ttaatattat
    21121 ttcctattcg ttttaattca aaaatcaaat cttgataact atttgtatca atggtgataa
    21181 aattcatacc aggatctagt agagttcgtc tagcatattc tgagaacgat aagcagttac
    21241 tttttgagat attttcattc aatttgacta attctaggtc agataaaaag acctttttta
    21301 aatttgttct atatcggtgc tccactctac tacctcatgt atttgttacg aaaatcttca
    21361 ctaagaggac ctgttttttc tacctcttta attaattcct gaatacaagt taacaaaata
    21421 gaaacatgtt cgtgagtaac ctgatgattt gttttagcaa ttatgaatac ttcatgaaca
    21481 tcacggctaa tttgttccaa cttttgtttt ttccaaaggt tgaaccattt ttccatctgt
    21541 ttttgtccat cagataatag taagctttta cggagaaaat cagaaaaatt atcctctcct
    21601 ttctctctca ttaaatctag tatttgtttt tcttccgttt ctgttaagcg aaattgtttc
    21661 cgaatactac gtatatctct tttcatatga tttatcctct ctcatagata cttgtactga
    21721 caatgtaagc ttacagacac tgtcagtacg ttttacaaaa tagattcaac atttttgtaa
    21781 ggctttgcga gctcagatat tgtgtccaca atatcccaaa aatcatatcg cctgccattt
    21841 caaacctcac ggttcaaaaa acaaacgata tgacaatgtg gtggctccgc ccccaaaccc
    21901 ccaagataaa tctaaattaa aaaaagtata acaaatactt tttgataaaa ttatcacaga
    21961 aaaaagagcc ctgtcggact cttacaaatt aaaacaatgt ctctgatatt catactgtct
    22021 aataccacta ctgtctttgt tcatcttgat agaaaaaaca aagtaatgat cacgaccgtc
    22081 taaagattta cttttgttaa gtttaaaata atgtttttga gacatagcca ttgtgcgtaa
    22141 aatatcatct gtgataaatg ttaatggtat atctaaagct gaatacttgt aaaaatctga
    22201 ctcaaactgt aaataagaat ctgaaaaata atctagctgt aatttatcat catataattc
    22261 tttacgattc atgtaattcc tccccttcta tctgtatatc gagtatatct tcccatttta
    22321 atcgaagaaa accagtgtct gattttatag atataaactc ttttccaatc tctttaacaa
    22381 tacctgatac tacttttctt tgattagaaa acttaaaaac aaaagttgca gggaatacat
    22441 tcgtataaag ttgacgaaca aatagaactt tctcttccaa tgatagggaa atggagatat
    22501 cttctttatt tttttctgcc caaagagaac tggaatgttc tgataaaaag aagcccatcc
    22561 acttagccat gccacgatcc tgatatactc gggcagactc aaaaggtaaa taagaacgat
    22621 tcatcatttt agtccatcta atcctccagc tgaatgacca ccaatgagtt tgcttctagc
    22681 aattgttcta gaagcttgat ctagggcatt acctttcaat agtgaagtga atccaaattc
    22741 tgttcgaata gcatcgattg cggactggag cctttcttct ttttctattt tctcaatatc
    22801 atcaaataat gaaatcaatc caaaggattc atccactaaa ccagaatagt taaccgcaac
    22861 attcctgata gctcctgaag tatatttagt gtgaaataac tttaaaacgt agtttgtcag
    22921 tagtgctgtt tgattagttg gttcaatttt catttgagta ttgatagaac gcttttgttc
    22981 cactttagag tagcctagat gtatagaaac tactgttgct tttttaccag atcttctcaa
    23041 tctaactgca acttgttctg ccatctcacg aagtatgatc tcaatatctc tttgtttaat
    23101 ataatctttt ggtaaaactt gagagttccc tatccctttt gactttggct tataaggttt
    23161 atgaacgttg ctttcgtcaa tcccattggc atgaaaccat aactctagtc ccataatccc
    23221 aagctctttt ttaatcaagt caggattagc ctgagccaat tctttaatcg aaaagatacc
    23281 taaattatgt aatcttttct ccgtgcgatt tccaattccc cagaaatctg tcattttagg
    23341 aatagtccat actttctttt cgacatcctc ataggaccaa ttggctctca ttgtcggagt
    23401 ctttttagct tcattatcaa gtgccaactt agctaataag ggattggcat tagacatacc
    23461 taccgttgaa tagattcctg tttttctcca aatctttttt tgaatggccg ccgaaataat
    23521 atctaactta tcttttcgac taatcctttt atcaggcaca aaataattta atgaactggt
    23581 taaatcaata aatccttcat caattgaata gggataaata tcgtctggag ccgcaaattc
    23641 ttgaaaaatt ttttgaatct ccatattgac tgcaatataa gtatccattc tcggaggaac
    23701 aatcacagtt gattttgccc attcctctat ataacgaaca taatctatcg ttgtcggtaa
    23761 accttgcttt ctagcattat aataagagaa tttgcgagtc tttacatcaa aaggtaaatc
    23821 ataggaacgt ccaacgttcg actttccaaa gaccttttta aacataggag aggaagcaag
    23881 aattaaacca gcagaattat ctgcacgact cataacacaa agcgaagtct taagtgggtg
    23941 taatcctcta tctacacatt ctacacttgc gtaaaaagat ttcatatcaa taaaggcaat
    24001 gtcactttga ggttcgagac tataatcaaa ccaactcata cttagtcctc taaaggcata
    24061 aagttcccaa ctattttccc tataatgcga ggattctcat cataaggcgc aaacttatct
    24121 ggatagttcc gattgagtga aactaatcta agcccatttt cttcacgata aactttcttg
    24181 ataaaggttt gactgtccca atctatcgca tagatagccc cgtcatagtc aaatcctgtt
    24241 tgcttaataa gggctacaga accattttta taagttggtt ccatagaaac accagatacc
    24301 cacgatgcaa agtcataatc aaattgacga ttaaaataaa ctgtatcgta attaccatca
    24361 tcaaagtaag ctgttcccgt accagctgat aatttttcat aaaccttata agcaaaacgc
    24421 tcaggaattt ctacaacctt cgcattctgt ttgttcaaca attctgtagc ataatgaagt
    24481 gttgcttttt gattcttttt agttagcttg agataggttt ctactatttc aaactctgat
    24541 tcaaaatatc gagggtctac attaaaaatc tcactcaatt tgcttagatt attttgattc
    24601 ggttttgttt tacctgattc ccaattaaag tatgaagctc tactaattcc taaactagaa
    24661 gcaagttgag attgagataa gccttgactc tctctttttt cttttaattt agtaggtgaa
    24721 aacatctctt ctcctttgta agtttattaa ctaacaaaag agtaccatag cttcttgaaa
    24781 aaatcaagag tttaataaca ccctggattt aaaataatca taaactacaa gaaatcatca
    24841 ctgaagaatg ctaaaacttt tgaaaaaatt tgaagaagaa aatagagaat ataaaaaagg
    24901 atcgttattt tttaattgac gatccaatag actttatttt aaaaatctaa ctctacaaac
    24961 catttcgatt agttaaatct ttcaatcttt cttctccaga tttaagcatc tctttctcca
    25021 cttgattcca ttctccaaat agtaaatcat gaagaacggt tgctgctgaa gttgtatttt
    25081 cttttgaatc atatacacaa cttctatctc gttgataaat ttgaattctt tcaaaaatag
    25141 ctagttcttc caattgccgt gtattatcaa ctagatgatt tacaatgaaa tcatgatgtt
    25201 cttttgaagt tgcgcgtgct tgatttggat tgatagagta cagttcttcg tatcggataa
    25261 gagtactcag ataggacaat tcgggcttgg ttgcgattaa agctaattgt acttcatatc
    25321 ccttactttt caagagttgt gctgttttct ttggaacatc aatcgttcgt aaagttccct
    25381 ctatcaaaag attgtatccc aaatgactca attctgttac taaagactct accattttac
    25441 ctgcaaaatc tttggtgtat tctacactat ctttgccata ttcttgctgc agttctaaat
    25501 agcgtggatg ctgagaacga aaactatc
//
LOCUS       DAVBNZ010000029        23842 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000029 DAVBNZ010000000
VERSION     DAVBNZ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23842
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.029"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(98..2356)
                     /locus_tag="VQ860_001227"
     CDS             complement(98..2356)
                     /locus_tag="VQ860_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3119655.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VQ860_001228"
     CDS             complement(2585..2815)
                     /locus_tag="VQ860_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET3119656.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VQ860_001229"
     CDS             3005..3688
                     /locus_tag="VQ860_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3119657.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VQ860_001230"
     CDS             3688..4422
                     /locus_tag="VQ860_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3119658.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VQ860_001231"
     CDS             4576..5433
                     /locus_tag="VQ860_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET3119659.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VQ860_001232"
     CDS             5575..6447
                     /locus_tag="VQ860_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET3119660.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ860_001233"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ860_001233"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET3119661.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VQ860_001234"
     CDS             7426..8637
                     /locus_tag="VQ860_001234"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET3119662.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VQ860_001235"
                     /pseudo
     CDS             8639..9181
                     /locus_tag="VQ860_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            9197..10006
                     /locus_tag="VQ860_001236"
     CDS             9197..10006
                     /locus_tag="VQ860_001236"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3119663.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10482..11213
                     /locus_tag="VQ860_001237"
     CDS             10482..11213
                     /locus_tag="VQ860_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119664.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAEVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTP
                     LIHNDRDIVTFTGNSRFKHRSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRF
                     FKKQALPRSSSQPSAEPMENIALGK"
     gene            11259..11462
                     /locus_tag="VQ860_001238"
     CDS             11259..11462
                     /locus_tag="VQ860_001238"
                     /inference="COORDINATES: protein motif:HMM:NF012956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3119665.1"
                     /translation="MDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIRQINIYNRT
                     DTAQDRLANFDVILLDSSGKEIE"
     gene            11487..11999
                     /locus_tag="VQ860_001239"
     CDS             11487..11999
                     /locus_tag="VQ860_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET3119666.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12657..13367
                     /gene="deoD"
                     /locus_tag="VQ860_001240"
     CDS             12657..13367
                     /gene="deoD"
                     /locus_tag="VQ860_001240"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3119667.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13390..13914)
                     /locus_tag="VQ860_001241"
     CDS             complement(13390..13914)
                     /locus_tag="VQ860_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET3119668.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13967..14203)
                     /locus_tag="VQ860_001242"
     CDS             complement(13967..14203)
                     /locus_tag="VQ860_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET3119669.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14271..15191)
                     /locus_tag="VQ860_001243"
     CDS             complement(14271..15191)
                     /locus_tag="VQ860_001243"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET3119670.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15389..15793
                     /locus_tag="VQ860_001244"
     CDS             15389..15793
                     /locus_tag="VQ860_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119671.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16009..16590
                     /locus_tag="VQ860_001245"
     CDS             16009..16590
                     /locus_tag="VQ860_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3119672.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16587..17864
                     /locus_tag="VQ860_001246"
     CDS             16587..17864
                     /locus_tag="VQ860_001246"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET3119673.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17882..18544
                     /gene="deoC"
                     /locus_tag="VQ860_001247"
     CDS             17882..18544
                     /gene="deoC"
                     /locus_tag="VQ860_001247"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET3119674.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18531..18920
                     /locus_tag="VQ860_001248"
     CDS             18531..18920
                     /locus_tag="VQ860_001248"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3119675.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19011..20063
                     /locus_tag="VQ860_001249"
     CDS             19011..20063
                     /locus_tag="VQ860_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET3119676.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20207..21742
                     /locus_tag="VQ860_001250"
     CDS             20207..21742
                     /locus_tag="VQ860_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119677.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21735..22793
                     /locus_tag="VQ860_001251"
     CDS             21735..22793
                     /locus_tag="VQ860_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3119678.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22796..23752
                     /locus_tag="VQ860_001252"
     CDS             22796..23752
                     /locus_tag="VQ860_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3119679.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         6918 a         4301 c         5437 g         7186 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt catccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttcgtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcaat caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccgc ttttatttgc
     3601 agcattttat tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggaatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag gttatctttg agggagtcga tattacggac
     3901 aagaagaatg acttgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gattgaaaat attaccttgt cacctatcaa gaccaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa ccgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttgttgta taataaaagt gagagggaaa aaggatgaaa
     5581 gtgattaatc aaaccttact agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagtta tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagat
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaatga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcatttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaagcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa ttatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     8701 ggcggaactt cgtcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 cagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctagg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca taagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt ggatcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caaggtcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccgtattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtatgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag cggatgatat ccgcaaggtt gttggggaat
    10681 tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt ggatgctacc
    10741 tagctcagat tgcagaggtt gaagcttacc aaaaatatcc tgatttttat aaccatgtat
    10801 tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact gtttggaatg
    10861 ctaagaatgg tttctgggat gttggtttgg aaagtcgtaa attagctgtt agtggaaaaa
    10921 ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat aatgatcgtg
    10981 atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa
    11041 gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg
    11101 gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct ctgcctcgat
    11161 cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa taggttactc
    11221 aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta
    11281 actatggtca caattctgtc actcatacaa actttcaatc taagccttgg tggcaagtag
    11341 atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc
    11401 aggatagatt ggcaaacttt gatgtcattc ttttagacag ttctggtaaa gaaattgagt
    11461 gaaaacgtat aacatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaag
    11521 cgcgctatgt tcggattgag ctagaaggct ataatgccct cagtcttgca gaagttgaag
    11581 ttttccgctt tatagctacg aatggtgaaa cggcgataca agtttctaag tcagttcaac
    11641 caatcagtca gactcctgtg aaggataaaa cattgacaat tcaacacagt ggagcttaca
    11701 ttgcccgcta ctccataact tgggaagaag ttacagtaga taaagatgga aaccaagttg
    11761 ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac tgcaggtttt gtcctcaacc
    11821 tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag acgggcctac
    11881 tatggaatag atggcaaaca atctatgaaa acagaccaat tttagctcaa ccccaccgta
    11941 aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat gtcttgtaat
    12001 ctgatggtac aatgatagtt agtttgtcta gtttataaga aagtactacc tgagcttgaa
    12061 taggactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa atcaaagagc
    12121 aaactaggaa actagccgca ggttgctcaa agcactgctt tgaggttgta gataagactg
    12181 acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag agattttcga
    12241 agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag aaaacttttc
    12301 taaaaataaa aacgaaagga tgggtaaact gtattcgctg aactgaatac gggcgactct
    12361 cctctaaatc aaaattaaga aagaaaggaa ttgaccccac cctaaaagca gtgggaaaaa
    12421 gatagttggt ctagcgagca tcgctcactg cgcccaactc ctattttccc ttcgcttttt
    12481 gatgggtttg gtatctttct caatataaaa tataaaataa agaaaggtag agcgtgtgtt
    12541 ttgatttgaa cacgagcgga aaactcggaa aatagataat ctgactgaaa aatcaggatt
    12601 tctcgtcagg ttcctaattt tcagtcgttt tcttctcgct ctttgtatca taaattatgt
    12661 ctatccatat tgctgctcag cagggtgaaa ttgctgataa aattcttctt cctggggatc
    12721 ctcttcgtgc taagtttatt gcggagaatt tccttggtga tgctgtttgt tttaacgaag
    12781 tgcgtaacat gtttggttac actggtactt acaagggtca ccgtgtatct gtcatgggaa
    12841 ctgggatggg aatgccatct atttcgattt atgcgcgtga gttaatcgta gactacggtg
    12901 tgaagaaatt gattcgtgtg ggaactgcag gttctttgaa tgaagaggtt catgttcgtg
    12961 aattagtttt ggcgcaggcg gctgcaacca actcaaacat cgttcgtaat gactggccac
    13021 agtacgattt tccacaaatt gctagctttg atttgcttga taaagcctac catatcgcca
    13081 aagaacttgg tatgactact cacgttggga acgttttgtc atctgatgtc ttttactcaa
    13141 attactttga aaagaatatc gagcttggta aatggggagt caaggctgtg gaaatggaag
    13201 cagcagctct ttactatctt gctgcccaat accatgttga tgcgctagct atcatgacca
    13261 tctctgatag cttggtcaat ccagacgaag acacaactgc agaagaacgt caaaatacct
    13321 tcactgatat gatgaaggtt ggtttggaaa ccttgattgc agaataatta tagccaaaaa
    13381 ggaagccctt tatgaattgt aggacttcct tttcttatcc agaaattgat ctagctctct
    13441 ctgatttcga agaatagtga ctttatgtga atattcttgg caaagttttt ggtaattttc
    13501 tttttgagtt ttgctacgcc catcccaaag aatccatctg ataaactccc agtcaaagcg
    13561 ttcagggcaa tctgccgcca tactttctct gacttttcca cggtatttaa gataacgctt
    13621 aaaggctcta aagagacagg tcaatggcaa aaaattgaga aagatgattt ggtcagcttc
    13681 ttgcattcgt tcttggtagt agcaccaaga ataattacca tcgatgaccc aagctttatg
    13741 cttggtgaga aagtttttta tctcggttaa catccattcg cagtcactgt cttgccaacc
    13801 aggttgaaat tggagtgtgt ccatgtgcag ttttggaatg gagtagtagt tagataactt
    13861 ttctgctaga gttgacttac cagaaccaga atatccgata attgtgattt tcattttcta
    13921 ccttttccta tttggagaca aaaaaacagc ctctatggac tgtttcttat ttagcaagtt
    13981 tagctgaaag acgagcttta tcgcggcttg ctttgttttt gtgaatcaaa cctttagttt
    14041 ctgctttatc gatagctgag ctagcagcac ggaaaagttc ttcagatggg tttgcttcga
    14101 aagcttttat agcagtacgc atagctgatt tttgagctga gttcttttcg ttttgtttaa
    14161 cgttcaattc agcgcgtttg atagctgatt taatgtttgc caatgttctt acctccatat
    14221 ttactaacta taccattata tatgaaaact tacgttttga caagggaaaa ttattttttt
    14281 aagtaaattt catcgatttc atggttcttg cttttatgaa gaatcacttc tgcacgattt
    14341 ctggttggtt caatataatt ttgtagattt gtgagattga tactggtcca gacctgatgg
    14401 gcaaaggctt ccacttcccc aatcggcatc tgagtaaaac gataatagta gctatcaggg
    14461 tcgttttggg ctaggctcag cattttcaag aaacggtcca gataccaact ttcaatatca
    14521 tccactccag catctacata gatggaaaag tcaaagaagt cagtgatata gagacgatcg
    14581 ttttgtggat tttgaaagac attgattccc tcaacaatta caaaatcagc agctttgaca
    14641 ctttgtttct cttcgggtac gatgtcgtaa acttcatgag aatagacagg aatatctaca
    14701 tcttgtccat ttttgatgcg gtccaagaag ttgagaagag cttccatatc atagctttca
    14761 ggaaatcctt tacgatttaa aatcccctgc tcaatcaagg tttgattggg atagagaaaa
    14821 ccatcagttg taaccaactc aaccgtagca tctgtaaacg tacgggacag taggatttga
    14881 agtaggcgac tggttgtgga ttttccaacg gcaacactcc cagaaacccc aataataaaa
    14941 ggttgagatt tactttcacg ttggaggaaa attccttttg aaaaggctaa atcttcctta
    15001 gttcgcttgt aaatctgaat cagatgagcc aaggggagat agatatctgt aacgtcttgg
    15061 agactgattt ggtcattaaa actcttgata gattccaatt cttcttctgt caaaggaggt
    15121 gttgtctttc gatgtaaaga ttgccaagtc tggcggctga ttttttcaaa atgtaaaaat
    15181 tcgttggtca tttgttttcc cctagatatt ttgtctatca taccataaaa atctaaaaaa
    15241 ataaagcggt ttcttgaatg tggtaagtca atggtatata gtataagtga tcaatttatt
    15301 gatgaaatag gagatagatt ctactgattt ataagtttat aagcttataa agggggcttt
    15361 ttagttcaca acttatagga ggtgtactat gaaaatctta aaacgttaca tattggaact
    15421 ctgttttatt ttaagttttg ctttaccttt tataaaagga gccaatgcag ataatggtat
    15481 atgctttgtg gaaacctatt acggttttac ttttttgatg gaacatgcta ttgtaacagc
    15541 tgtctttatc tattcgtttt taattgcttt cttactaaaa aaacgatggg cgaaatggat
    15601 tgctgctggt agttattgct ttttagtcct atggattgcg acagagggtt atttcttccg
    15661 catgtcacta gaagatttga tacgactttg gacaagtttg gaaatcctga cacaaacgta
    15721 tcagttgggc ttttatctaa acattttgtt aggaattttg ttgataataa agtattttaa
    15781 ggttaagcaa tagaaataat aatctgcctg attatagatg ataaactttt tgtttttatc
    15841 tggactgtga tatttatagt tctaaatggt ttattattta taagtgttga aagagattga
    15901 agaaaatggc ttcgtgactt gctttcttcg gtctttttcg ttttattatc aatttgtaaa
    15961 cgatttacaa tttgagtcaa attatggtaa aatagtgtca tgagtaaaat gtattatgca
    16021 gaaaatcctg acgctgctca cgacattcat gagttgagag tagagttgtt gggacaaaaa
    16081 atgacctttt taacggatgc gggtgttttt agcaagaaaa tagttgactt tggaagtcaa
    16141 ctattgctca agtgtcttga ggtcaaccaa ggagaaactg tccttgatgt aggctgtggt
    16201 tacggacctt tgggtttgtc cttagctaag gcttatggag ttcaggctac tatggttgat
    16261 atcaacactc gtgccttgga tttagctcgg agaaatgctg aaaaaaataa tgcaaaagcg
    16321 acgattttcc agtccaacat ctatgaacaa gttgaaggac attttgatca tgtcatttcc
    16381 aatcctccta tccgtgcggg caagcaagtc gttcatgaaa tcattgagaa aagtaaagat
    16441 ttcttggaaa ctggtgggga tttgacaatc gtcatccaga aaaaacaagg ggctccaagt
    16501 gctaagtcca agatggagga tgtgtttggt aattgtgaaa tccttaaaaa agacaaggga
    16561 tactatatcc ttagaagtgt gaaagaatga gagcagttga tttaatacaa aaaaaacgag
    16621 acggtcaaga actgacttca agtgaaattg aatggctggt agaaggctat gtgtcaggaa
    16681 ctgttcctga ttatcagatg tctgcctttg ctatggctgt ttattttaaa ggaatgacga
    16741 ctcgtgaaat ttctgattta acgatgaata tggttaagac tgggcaagag tttgacctgt
    16801 cagccattga tggtgtgaaa gttgacaagc attctactgg tggtgtcggc gataaggtaa
    16861 ccttgatttt agctcctctt gttgctagct tcggtgtgcc tgtagcaaaa atgagtggtc
    16921 gtggtcttgg ccatacaggc ggaacaattg ataaattgga gtccattaag ggctatcaag
    16981 tagaacgtag tcaagaggat tttattcgtc aggttcagga tattggagta tctgtcattg
    17041 ggcaatcaga ccagctggtc aaagcagata agcttctcta tgcccttcgt gatgtgaccg
    17101 caactgtcga cacgattcct ttgattgcga gttcggtgat gagcaagaaa attgcggcag
    17161 gggcggatgc tattttgcta gacgtgactg tcggtgaggg tgccttcatg aagacggttg
    17221 atgaggcgcg tgagttggct caaactatgg tagatcttgg taaggttgtt ggacggaaga
    17281 cagtagcagt gattacggat atgagccagc ctttgggacg agcgattgga aatcgtctgg
    17341 aaatccttga agcattggag attttgcaag gtcaaggacg tcaggatatt acccacttta
    17401 tttgtgaatt ggctcaaatt atgcttggtt tggcaaatgt taacaaaact gttgaagaag
    17461 ttcaccaaca tcttgagaat ggtcaagcac tggctaagtt tgaggaaatg gtgcaagccc
    17521 aaggtggaga cttggaagac ctctatcgtc ctgtaaatgt agctcatgtg gtggaaatcc
    17581 ctgctcagga aacgggtgtc atttcagctc ttccagctat ggactttggt ctttatgcca
    17641 tgaggctggg tgctggtcgt gcagttaagt ctgatgcctt ggactatgaa acaggaattg
    17701 tttttgaaaa gaagattgga gactccgttc aaaagggtga aattgttgca aaagtataca
    17761 caaatgaaaa aattccacct caactagtta cagatttcca aaaatgtgtt aaaataagtg
    17821 atgaagtgaa aaaaatccgt gaaattgtag aaatcatctc ctaaatggag ggaaaaccga
    17881 aatgaaatta aataaatata tagatcatac gcttttaaaa caagatgcaa agaaaaaaca
    17941 aattgatagt ttgttgtctg aggctagaga gtatgacttt gccagtgttt gcgttaatcc
    18001 gacctgggtt gaacatgcta aaaaaggact tgaaggcaca gatgttaagg tttgcacagt
    18061 agtaggtttc cctttgggag caacaacttc agccgtgaaa gcatttgaga caaaagaagc
    18121 tatccaaaat ggtgcagatg agattgatat ggtgatcaat gttggagctc tcaaatcagg
    18181 taatttagcc ttggttgagt cagatattcg cgcagtagtg gaagcaagtg gtgataagtt
    18241 agtgaaagtc attattgaag cttgccttct gacagaccaa gaaaaagttg ttgtttgcca
    18301 attggcccaa aaagctgggg ctgactttgt caaaacatct actggctttt caactggtgg
    18361 tgctacgata gcagatgtta cattaatgcg tgaaacagtt ggatctgata tgggtgtcaa
    18421 ggccgccggt ggagctcgtt cttatgcaga tgctcttgcc tttgtcgaag caggtgcgac
    18481 ccgtatcgga acgtcagctg gggtagctat tttaaaagga gaattggcag atggcgacta
    18541 ctgagttgat tgaactggca attgaaacca gcaaacatgc ctatgtcccc tattctcact
    18601 ttcctatcgg agcagtttta gtagctaaag acggaagtgt ttacacggga gtgaatattg
    18661 aaaatgctag ctatcctttg accaattgcg gtgagagaac agctattttt aaggctatat
    18721 ctgaaggcca aagagaattt tcagaattga ttgtctatgg tcaaactgaa aaaccgattt
    18781 caccatgtgg tgcttgtcgc caagtaatgg tcgaattttt tgaacaagat ttaaaagtga
    18841 ccttagtcgc aaaagataaa tcgacggtcg agatgacggt cggggagtta cttccatatt
    18901 cttttacaga cttaaattag tctgagtcgc tctttgagtg gcaagggtct ttgtgaccaa
    18961 tcaatccata cttgcaacat cgttgcacat cttatttagg aggttcagta atgaacaaga
    19021 aacaatggct aggtcttggc ctagttgcag tggcagcagt tggacttgct gcatgtggta
    19081 accgctcttc tcgtaacgca gcttcatctt ctgatgtgaa gacaaaagca gcaatcgtca
    19141 ctgatactgg tggtgttgat gacaaatcat tcaaccaatc agcttgggaa ggtttgcagg
    19201 cttggggtaa agaacacaat ctttcaaaag ataacggttt cacttacttc caatcaacaa
    19261 gtgaagctga ctacgctaac aacttgcaac aagcggctgg aagttacaac ctaatctttg
    19321 gtgttggttt tgcccttcac aatgcagttg aagaagcagc taaagaacac actgacttga
    19381 actatgtctt gattgatgat gtgattaaag accaaaagaa tgttgcgagc gtaactttcg
    19441 ctgataatga gtcaggttac cttgcaggtg tggctgcagc aaaaacaact aagacaaaac
    19501 aagttggttt tgtaggtggt atcgaatctg aagttatctc tcgttttgaa gcaggattca
    19561 aggctggtgt tgcgtcagta gacccatcta tcaaagtcca agttgactac gctggttcat
    19621 ttggtgatgc ggctaaaggt aaaacaattg cagccgcaca atacgcagcc ggtgcagata
    19681 ttgtttacca agtagctggt ggtacaggtg caggtgtctt tgcagaggca aaatctctca
    19741 acgaaagccg tcctgaaaat gaaaaagttt gggttatcgg tgttgaccgt gaccaagaag
    19801 cagaaggtaa atacacttct aaagatggca aagaatcaaa ctttgttctt gtatctactt
    19861 tgaaacaagt tggtacaact gtaaaagata tttctaacaa ggcagaaaaa ggagaattcc
    19921 ctggcggtca agtgatcgtt tactcattga aggataaagg ggttgacttg gcagtaacaa
    19981 acctttcaga agaaggtaaa aaagctgtcg aagatgcaaa agctaaaatc cttgatggaa
    20041 gcgtaaaagt tcctgaaaaa taatggatgg aagtcatttc ttaggaagcg gccaagggcc
    20101 gcttttttaa gagttgagac aaagtcattt tgtctcagta aagcttgcta ctagacaaac
    20161 tagcaagttt tattgaaata aaataagact ctgaaaggaa gagcacatgg cacacgaaaa
    20221 tgtcattgag atgcgtgata ttaccaaggt gtttggtgga tttgttgcca acgacaaaat
    20281 caacttgcac ctacgaaaag gtgaaattca tgcactttta ggagaaaatg gggctggtaa
    20341 gtccacgcta atgaacatgt tagcagggct tcttgaacca actagtggtg aaatcgcggt
    20401 caacggtcaa gttgtcaatc tcgactcccc atctaaagca gctagcttgg gaatcgggat
    20461 ggttcaccag cactttatgt tggttgaagc cttcacagtg gctgaaaaca tcattttagg
    20521 tagtgaattg actaaaaatg gtgtgctaga tatcgctgga gctagcaaag aaatcaaggc
    20581 tctttctgaa cgttatggct tagctgttga cccttctgcc aaggtagcag atatctcagt
    20641 tggagcccaa caacgtgtag aaattttaaa aacactttat cggggggctg atatccttat
    20701 ctttgacgaa ccaacggctg ttttgactcc atcagaaatt gatgagttga tggctattat
    20761 gaaaaatctt gtcaaagaag gaaaatcaat tatcttgatt acccacaaat tggatgaaat
    20821 tcgcgcagtt tctgaccgtg ttacagttat ccgtcgtggg aaatcaattg aaaccgttga
    20881 aattgcaggg gctaccaatg ctgatttggc ggaaatgatg gtagggcgtt ctgtttcctt
    20941 taaaacagag aagcaagcct ctaaaccaaa agaagtggtt ttgtctatca aagatttggt
    21001 ggtcaatgaa aaccgtggtg ttccagctgt taaaaatctg tccttggatg ttcgtgctgg
    21061 agagattgtt ggtattgcgg ggattgatgg aaatggtcag tctgaactga ttcaagccat
    21121 tacaggtctt cgtaaggttg aatctggtag cattgagcta aaaggagatt caattgtagg
    21181 cttgcaccca cgtcagatta cagaactaag tgttgggcac gttccagaag accgtcaccg
    21241 tgatggcttg attttggaaa tgatgatatc tgaaaatatt gcccttcaaa cctactataa
    21301 agaaccacat agtaaaaatg gaattttgaa ttattcaaat attacttctt atgctaaaaa
    21361 gctgatggaa gagtttgatg ttcgcgctgc cagtgaatta gttcctgcag ctgcactctc
    21421 aggaggaaat caacaaaaag caattattgc tcgtgaaatt gatcgagatc ctgatctcct
    21481 tatcgttagc cagccaactc gtgggttgga tgtcggtgcc attgagtata tccacaaacg
    21541 cttgattgaa gagcgtgata atggcaaggc tgtccttgtt gtcagctttg aattggatga
    21601 gattttaaac gtctcagacc gtattgccgt tatccacgat ggtaagattc aaggtattgt
    21661 atcaccagaa acaaccaata aacaagaact tggtgtcttg atggctggtg gaaacttggg
    21721 aaaggagaag agtgatgtct aaaaaattac aacaaatttc ggttcccttg atttctgtat
    21781 ttctaggaat tttactcgga gccattgtca tgtggatctt cggttatgat gctatttggg
    21841 gctacgaaga attgttctat acagcctttg gcagtctgcg tgggattgga gaaatcttcc
    21901 gtgctatggg tcctctggtc ttgattggtc ttggttttgc ggttgccagt cgagctggtt
    21961 tctttaacgt cggacttcct ggtcaggctt tggcaggttg gattctcagt ggttggtttg
    22021 cgctgtcgca tccagatatg ccccgtccct tgatgattct agcaaccatc gtgattgcct
    22081 tgattgctgg tgggattgtc ggagcgattc caggtattct tagggcctat ctagggacgt
    22141 cagaggttat tgtaaccatc atgatgaact acattgtctt gtatgtaggg aatgccttta
    22201 tccatgcttt ccctaaagac ttcatgcaaa gtacagattc gaccattcgt gttggggcta
    22261 atgcaactta tcagacacct tggttggctg agttgactgg taactcacgg atgaatattg
    22321 gtattttctt tgccatcatt gccgttgcag ttatttggtt catgctcaag aaaacaactc
    22381 ttggttttga aatccgtgca gttggtctta atccacatgc ttcagaatat gctggtattt
    22441 ctgccaagcg gactattatc ctatctatga ttatttcagg tgccttggca ggtcttggtg
    22501 gagctgttga aggtttggga accttccaga acgtctatgt tcaaggttcg tcattagcta
    22561 tcggatttaa cggaatggcg gttagtttgc ttgcggccaa ctcaccaatt ggtatactct
    22621 ttgcagcctt cctatttggc gttctccaag ttggggctcc tggtatgaat gcggcgcagg
    22681 taccatctga gcttgtcagc attgtaacag cgtctattat cttctttgtc agtgttcatt
    22741 accttatcga acgctttgtc aaaccgaaaa aacaagttaa aggaggtaag taaagatgtc
    22801 tattataacc ttgctccccc tcttggtgtc ttctatgctg atttactcag cacctctcat
    22861 ctttacaagt atcggtggtg ttttctctga acgtggtggt gtggtaaacg ttggccttga
    22921 aggaattatg gttatgggtg ccttttctgg agttgtcttt aaccttgaat ttgcagaaca
    22981 atttggagca gcaactccat ggctatcctt gcttgtagca ggattggttg gtagtgtttt
    23041 ctctatcatc cacgcagcag cgacggttca tttccgtgca gaccatgttg tcagcggtac
    23101 ggtattgaac ttgatggcgc ctgccttggc tgttttctta gttaaagttc tttataacaa
    23161 aggacaaacc gacaacctaa gtcaaacttt tggacgcttt gatttcccag tcttggcaaa
    23221 tatcccagtg attggtgata tcttcttcaa gtcaactagt ctacttggtt atctggcgat
    23281 tgccttctca ttccttgctt ggtttattct ctttaagact caatttggtc ttcgtctccg
    23341 ctctgtcggt gaacatcctc aagcagcgga taccttggga atcaacgtct acaagatgag
    23401 atatttaggg attattattt caggttttct aggtggaatt ggcggagcga tttatgcgca
    23461 atcaatctca gttaacttct cagtgacaac tattgttgga cctggattta tcgcccttgc
    23521 tgcgatgatc tttgggaaat ggaatccaat cggtgctatg ctttctagtc tcttctttgg
    23581 actttcacaa agtttggctg ttatcggttc tcaattgccg ttcctacaag gagtgccagc
    23641 ggtttatctt caaattgcac cttatgtttt gacaattctt gtcttagcag ccttctttgg
    23701 aaaagcagtc gcaccaaaag cagatggtat caactacatc aaatcaaaat aagcatacaa
    23761 aaaaacgtca gtccaatgac tgaactgccc cccaaaagtt agacagaaaa aatctaactt
    23821 ttggggtgtt tttattatga aa
//
LOCUS       DAVBNZ010000030        23291 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000030 DAVBNZ010000000
VERSION     DAVBNZ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.030"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            60..929
                     /locus_tag="VQ860_001253"
     CDS             60..929
                     /locus_tag="VQ860_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3119680.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            933..1889
                     /locus_tag="VQ860_001254"
     CDS             933..1889
                     /locus_tag="VQ860_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3119681.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            1889..2653
                     /locus_tag="VQ860_001255"
     CDS             1889..2653
                     /locus_tag="VQ860_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119682.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            2653..3363
                     /locus_tag="VQ860_001256"
     CDS             2653..3363
                     /locus_tag="VQ860_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119683.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQETTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            3671..4327
                     /locus_tag="VQ860_001257"
     CDS             3671..4327
                     /locus_tag="VQ860_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3119684.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            4435..5530
                     /gene="prfB"
                     /locus_tag="VQ860_001258"
     CDS             join(4435..4506,4508..5530)
                     /gene="prfB"
                     /locus_tag="VQ860_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET3119685.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            5548..6240
                     /gene="ftsE"
                     /locus_tag="VQ860_001259"
     CDS             5548..6240
                     /gene="ftsE"
                     /locus_tag="VQ860_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET3119686.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            6233..7159
                     /locus_tag="VQ860_001260"
     CDS             6233..7159
                     /locus_tag="VQ860_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3119687.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            7445..9625
                     /locus_tag="VQ860_001261"
     CDS             7445..9625
                     /locus_tag="VQ860_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3119688.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            9677..10492
                     /locus_tag="VQ860_001262"
     CDS             9677..10492
                     /locus_tag="VQ860_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3119689.1"
                     /translation="MKFLTLNTYSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            10632..11975
                     /locus_tag="VQ860_001263"
     CDS             10632..11975
                     /locus_tag="VQ860_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3119690.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIADSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQSMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            12352..13542
                     /locus_tag="VQ860_001264"
     CDS             12352..13542
                     /locus_tag="VQ860_001264"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET3119691.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKAKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            14095..15030
                     /locus_tag="VQ860_001265"
     CDS             14095..15030
                     /locus_tag="VQ860_001265"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET3119692.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            15064..16101
                     /locus_tag="VQ860_001266"
     CDS             15064..16101
                     /locus_tag="VQ860_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3119693.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            16274..16879
                     /locus_tag="VQ860_001267"
     CDS             16274..16879
                     /locus_tag="VQ860_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET3119694.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            17035..17565
                     /locus_tag="VQ860_001268"
     CDS             17035..17565
                     /locus_tag="VQ860_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET3119695.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            17586..18671
                     /gene="rlmN"
                     /locus_tag="VQ860_001269"
     CDS             17586..18671
                     /gene="rlmN"
                     /locus_tag="VQ860_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET3119696.1"
                     /translation="MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLLFNTMKRDRQKAVAAVNP"
     gene            18671..19153
                     /locus_tag="VQ860_001270"
     CDS             18671..19153
                     /locus_tag="VQ860_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3119697.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            19155..20696
                     /locus_tag="VQ860_001271"
     CDS             19155..20696
                     /locus_tag="VQ860_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3119698.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQTKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(20752..21555)
                     /locus_tag="VQ860_001272"
     CDS             complement(20752..21555)
                     /locus_tag="VQ860_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3119699.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(21638..21859)
                     /locus_tag="VQ860_001273"
     CDS             complement(21638..21859)
                     /locus_tag="VQ860_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119700.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(22338..22547)
                     /locus_tag="VQ860_001274"
     CDS             complement(22338..22547)
                     /locus_tag="VQ860_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119701.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            22717..22989
                     /gene="rpsP"
                     /locus_tag="VQ860_001275"
     CDS             22717..22989
                     /gene="rpsP"
                     /locus_tag="VQ860_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET3119702.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            23009..23248
                     /locus_tag="VQ860_001276"
     CDS             23009..23248
                     /locus_tag="VQ860_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET3119703.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
BASE COUNT         6969 a         4223 c         5092 g         7007 t
ORIGIN      
        1 agaacctatc aaaaagtgag ggaaacccct cggaattata aatagaaaga gtgaatctta
       61 tgctccaaca actcgtaaat ggtttgattc taggtagtgt ttacgcgctg ttagccctag
      121 gatataccat ggtttacgga attatcaagc tcatcaactt cgcccatggt gatatttata
      181 tgatgggagc ctttatcggt tatttcttga tcaattcttt ccaaatgaat ttctttgtag
      241 cgcttattgt agctatgcta gcgacagcta ttcttggtgt cgtgattgag tttcttgctt
      301 accgaccttt gcgccactct actcgtattg ctgttttgat tacggctatt ggggtttctt
      361 tcctattgga gtatggaatg gtctatctgg ttggtgccaa tacccgtgcc ttccctcaag
      421 cgattcaaac agttcgatat gatttgggac caattagctt aacaaatgtg cagttaatga
      481 ttttgggcat ttccttgatt ttgatgattt tgttacaagt cattgtccaa aagactaaga
      541 tggggaaagc catgcgtgca gtatcagtag atagcgacgc ggcgcaattg atggggatca
      601 atgtaaaccg tacgattagc tttaccttcg ctttgggttc tgctcttgcg ggtgcggctg
      661 gtgttctgat tgctctttat tataactctc ttgagccttt gatgggggtt actccaggtc
      721 ttaaatcttt cgttgccgca gtacttggtg gtatcggaat tattcctggt gcggctcttg
      781 gtggctttgt gattggtcta ttggaaacct ttgcgactgc ctttgggatg tcagatttcc
      841 gtgatgccat tgtttatgga atcttgttgt tgatcttgat tgtccgccca gctggtatcc
      901 ttggtaagaa tgtgaaagag aaggtgtaaa cgatgaagga aaatttaaaa gttaatattc
      961 tatggttact ccttttgtta gctggctata gcttgattag tgtactggtt tcagtcggag
     1021 tacttaatct attctatgta cagattttac aacaaattgg aattaatatt attttggctg
     1081 ttggtctcaa cttaatcgtt ggtttttcag gacaattttc acttggtcat gctggtttca
     1141 tggcgattgg tgcctatgca gcagctatta ttggttctaa atcaccaacc tacggtgcct
     1201 tctttggagc tatgcttgta ggggctttgc tttcaggagc agttgcctta cttgtcggca
     1261 ttccaacctt gcgcttgaag ggggactatc ttgcggtagc aactctaggt gtttctgaaa
     1321 ttatccgtat ctttatcatc aatggtggaa gccttacaaa tggtgcggca ggtattttag
     1381 ggattcctaa ctttacaact tggcaaatgg tttacttctt tgtcgtgatt acaaccattg
     1441 caaccttgaa cttcttgcgt agcccaattg gtcgttcaac cctctctgtt cgtgaagatg
     1501 aaatcgctgc tgagtcagtt ggggttaata cgactaaaat taaaatcatc gcttttgtct
     1561 ttggtgccat tactgcaagt attgctgggt cacttcaggc aggatttatc gggtctgttg
     1621 taccgaaaga ttacaccttc atcaactcaa tcaacgtttt gattattgtt gtatttggtg
     1681 gactcggttc cattacaggt gcgattgttt cggctattgt tctgggaatt ttaaatatgc
     1741 ttctccaaga tgttgctagt gtgcgtatga ttatttacgc tttggccttg gtattggtaa
     1801 tgattttcag accaggtgga ctccttggaa cgtgggaact gagcctatca cgtttcttta
     1861 aaaaatctaa gaaggaggaa caaaactaat ggcattactt gaagtaaaac agttaaccaa
     1921 acattttggt ggtctaacag ctgttggaga tgtgactctt gaattgaacg aaggggaact
     1981 ggttggatta atcggtccaa acggagctgg gaaaaccacc cttttcaacc ttttgaccgg
     2041 tgtttatgaa ccaagcgagg gaacagtaac cctagatggt caccttttga atgggaaatc
     2101 accttataag attgcctctt tgggacttgg acgtactttc caaaatatcc gtctctttaa
     2161 agatttaaca gttttagata atgttttgat tgcttttgga aaccatcaca aacagcatgt
     2221 ttttactagt ttcttacgct taccagcttt ttacaagagt gaaaaagaat taaaggctaa
     2281 agctttggaa ttgttgaaaa tctttgattt agatggtgat gcagagactc ttgctaaaaa
     2341 tctttcctac ggacaacaac gtcgtttgga aattgttcgt gcccttgcta cggaacctaa
     2401 aattctcttc ttagatgaac cagcagcagg tatgaaccca caggaaacag ccgaattgac
     2461 tgagttaatt cgtcgtatca aagatgaatt taagattaca atcatgttga ttgaacacga
     2521 tatgaatctg gtcatggaag taacagaacg tatctacgta cttgaatatg gccgtttaat
     2581 tgctcaagga actccagacg aaattaagac caataaacgc gttatcgaag cttatctagg
     2641 aggtgaagcc taatgtctat gttaaaagtt gaaaatcttt ctgtgcatta cggtatgatc
     2701 caagcagtcc gtgatgtaag ctttgaagtt aatgaaggag aagttgtttc ccttatcggt
     2761 gccaacggtg caggtaagac aactattctt cgcaccttgt caggtttggt tcgaccaagt
     2821 tcaggaaaga ttgaattttt aggtcaagaa atccaaaaaa tgccagctca gaaaatcgtg
     2881 gcaggtggtc tttcacaagt tccagaagga cgccacgtct ttcctggctt gactgttatg
     2941 gaaaatcttg aaatgggagc tttcttaaag aaaaatcgtg aagaaaatca agcaaacttg
     3001 aagaaggttt tctcacgctt tcctcgtctt gaagaacgta agaaccaaga tgcagctact
     3061 ctttcaggag gggaacaaca aatgcttgcc atgggacgcg ctcttatgtc aacaccaaaa
     3121 cttcttcttt tagatgaacc atcaatggga cttgccccaa tcttcatcca agagattttt
     3181 gatatcattc aagatattca gaagcaagaa acaaccgtcc tcttgattga acaaaatgcc
     3241 aataaagcac tcgcaatctc tgaccgagga tatgtattgg aaacaggaaa aatcgtccta
     3301 tcagggacag gaaaagaact cgcttcatca gaagaagtca gaaaagcata tctaggtggc
     3361 taaaacaatc cagtggattg ttttagtcgg cagatgaaga ttacgaagta atcatcaata
     3421 tagtccgggg gaccttttta gtcggtagat tgagattgca aacaaatatg catctacatt
     3481 gaaagcttaa tttctaataa ttgaaaaaat cgaatgaaaa atttcttacc ttcattcaca
     3541 gagctctatt tcagagctct ttttgctagc ttattcatac ttttctgaat ttcgaaaaag
     3601 aaatgtaagc gtttgataga tttacaaaaa gattgtataa tagggataag aatagaaaag
     3661 gagaagtctc atggcagtta aagattttat gacccgcaag gtagtttata ttagtccaga
     3721 tacaacagta tctcatgcag cagatttgat gagagagcaa ggtttgcacc gtctgcctgt
     3781 tatcgaaaat gatcaattag ttggtttggt gactgaggga accattgcac aagcaagtcc
     3841 atctaaagca acaagtcttt ctatctatga gatgaattat cttctgaata agacaaaagt
     3901 aaaagatgtc atgattcgcg atgttgtcac tgtctcaggc tatgctagtc tagaagatgc
     3961 aacttatctg atgttgaaaa ataagattag tattctccct gtcgtagata accatcaagt
     4021 atacggagtt attactgacc gtgacgtttt ccaagccttt cttgaaattg caggttatgg
     4081 cgaagaaggg attcgtgtac gctttgttac agaagatgaa gttggtgttc ttggaaaaat
     4141 tgtttctttg attgtagaag aaaatttgaa tatctcccat acagtcaata ttccgcgtaa
     4201 ggatggtaag gtgattatcg aagtgcaaat cgatggatca attgatttac cagccttgaa
     4261 agaaaaattt gaagcaaatg gtattcaagt ggaagaaatc gctcgcactt cagcaaaagt
     4321 cttgtaagaa gggaagccca aaggcttctt ttttcatgaa aaggggatta gagcaaaaga
     4381 tggaaagaaa tgataaaata tgctataatg aaataatgta aaaaaggagt atttatggac
     4441 atttcagtaa ttcgtcagaa aattgacgca aatcgtgaaa aattagcttc tttcaggggg
     4501 tctctttgac ctcgaagggc tagaggaaga gattgccatc ttggaaaaca agatgacaga
     4561 acctgatttt tggaacgata atattgcggc ccaaaaaacg tcgcaagaat tgaatgaatt
     4621 aaaaaacact tacaatacct tccataagat ggaagagttg caggatgaag tcgaaatttt
     4681 attggatttt ttggctgaag acgagtcagt gcatgatgaa ctggtagcgc agttagccga
     4741 acttgataag ataatgacca gctacgagat gactctacta ttgtcagaac cttatgacca
     4801 caacaatgcc atcttggaaa tccatccagg ttctggtggt actgaggcgc aggactgggg
     4861 tgatatgttg cttcgtatgt atactcgtta tggtaatgct aaaggcttta aagtggaagt
     4921 gttggattac caagcaggtg atgaggctgg tattaagtcg gtaactttat catttgaagg
     4981 gcctaatgcc tatggtctcc tcaagtcaga aatgggtgtt catcgcttag tgcgaatctc
     5041 accatttgac tctgccaaac gtcgccatac ctctttcaca tctgtagaag tgatgccaga
     5101 attggatgat actattgaag tggaaatccg tgaagatgat atcaagatgg ataccttccg
     5161 ttcaggtggt gccggtggac aaaacgtcaa taaggtttca acaggtgtac gtttaaccca
     5221 cattccaact ggaattgttg tccaatcaac agtggatcgt acccagtatg gaaatagaga
     5281 tcgtgccatg aagatgttgc aggctaagct ctatcaaatg gagcaagata agaaggctgc
     5341 ggaggtagat tctctcaaag gtgagaaaaa ggagatcact tggggaagcc aaatccgttc
     5401 ttatgtcttc acgccttata ctatggtaaa agatcaccga actagctttg aggttgctca
     5461 ggtagataag gttatggatg gggacctaga tggttttatc gatgcttatc tcaagtggcg
     5521 aattagctaa gatagaaagg aactcacatg tcaattattg aaatgagaga tgtcgttaaa
     5581 aaatacgaca acggaacgac tgctctacgc ggtgtttcgg ttagcgttca accgggggaa
     5641 tttgcttaca tcgtaggacc ttcaggagca gggaagtcaa cttttattcg ttctctgtat
     5701 cgtgaagtaa aaatcgataa aggaagtcta tcagttgctg gttttaatct ggttaagatc
     5761 aaaaagaaag atgtcccgct tctacgtcgt agtgttgggg ttgtcttcca agattataaa
     5821 ttgttaccaa agaaaactgt ctatgaaaat attgcttacg ctatggaagt aatcggggaa
     5881 aatcgccgta atatcaaaag acgagtgatg gaagttttgg acttggttgg attgaagcat
     5941 aaggttcgtt ctttcccaaa tgaactctca ggtggggagc agcagcgaat tgcgattgcg
     6001 cgtgcaattg taaataatcc caaagtattg atagctgatg agccaacagg aaatctggat
     6061 ccggataatt catgggaaat tatgaatctc ttggaacgga ttaacctaca agggacaact
     6121 attttgatgg cgactcataa tagccagatt gtaaatacct tgcgccaccg tgtcattgcc
     6181 attgaaaatg gccgtgtcgt tcgtgacgaa tcaaaaggag agtatggata cgatgattag
     6241 tagatttttt cgccatttat ttgaagcctt aaaaagtttg aaacgaaatg gttggatgac
     6301 agtagctgct gtcagttcag tcatgattac tttgaccttg gtggcaatat ttgcatctgt
     6361 tattttcaat acagcgaaat tagctacaga tattgaaaat aatgtccgtg tagtagttta
     6421 tatccgaaag gatgtggaag ataatagtca gacaattgaa aaagaaggtc aaactgttac
     6481 aaataatgac taccacaagg tatatgattc tttgaagaac atgtctacgg ttaaaagtgt
     6541 taccttttca agtaaagaag aacaatatga aaaattaacc gagataatgg gagataactg
     6601 gaaaatcttt gaaggagatg ccaatcctct ctatgatgcc tatattgtag aggcaaacac
     6661 tccaaatgat gtaaaaacta tagccgaaga tgctaaaaaa attgaaggtg tctctgaggt
     6721 tcaagatggc ggtgccaata cagaaagact cttcaagtta gcttcattta tccgtgtttg
     6781 gggactaggg attgctgctt tgttaatttt tatcgcagtt ttcttgattt caaataccat
     6841 tcgtattacc attatttccc gcagtcgcga aattcaaatc atgcgcttgg ttggagctaa
     6901 aaacagttat atccgtggac cgttcttgtt agaaggagcc tttatcggtt tattgggagc
     6961 tatcgcacca tctgttttgg tctttattgt ttatcaaatt gtttaccaat ctgtcaacaa
     7021 atcgttggta gggcaaaatc tatccatgat tagtccagat ttatttagtc cgttgatgat
     7081 tgccctacta tttgtgattg gggttttcat tggttcattg ggatcaggaa tatccatgcg
     7141 ccgattcttg aagatttagg taaaatagct gcttttatga ggagattgta aaatctcctt
     7201 ttttgctaca agagtttttg aaaagagatg cgtagaagaa aagagcttcc aaagaagtcc
     7261 cccagagaag acttcttgat ggctaatttg aacttgaaat ttggcgcact agaaattttt
     7321 tagaaaaaag tgtaattttt ttataaaagc ctttacaaaa aaaattaaag tggtataatt
     7381 aaatcataga aggtgcaaac gttttcgtaa aacgtttgcc taaataaaaa taaaggagat
     7441 ttgaatgatg aaagatacat tcaaaaatgt cttgtctttc gaattttggc aaaaattcgg
     7501 taaggctttg atggtagtta tcgcggttat gccggctgct ggtttgatga tttcaatcgg
     7561 taagtctatc gtgatgatta acccaacctt tacaccactt gtcatcacag gtggaattct
     7621 tgagcaaatc ggttgggggg ttatcggtaa ccttcacatt ttgtttgccc tagccattgg
     7681 aggaagctgg gctaaagaac gtgctggtgg tgctttcgcc gctggtcttg ccttcatctt
     7741 gattaaccgt atcactggta caatttttgg tgtatcaggc gatatgttga aaaatccaga
     7801 tgctatggta actactttct ttggtggttc aatcaaagtt gctgattact ttatcagtgt
     7861 tcttgaagct ccagccttga acatgggggt attcgtaggg attatctcag gttttgtagg
     7921 ggcaactgct tacaacaaat actacaactt ccgtaaactt cctgatgcac tttcattctt
     7981 caacgggaaa cgtttcgtac catttgtagt tattcttcgt tcagcaatcg ctgcaattct
     8041 acttgctgct ttctggccag tagttcaaac aggtatcaat aacttcggta tctggattgc
     8101 caactcacaa gaaactgctc caattcttgc accattcttg tatggtactt tggaacgttt
     8161 gctcttgcca tttggtcttc accacatgtt gactatccca atgaactaca cagctcttgg
     8221 tggtacttat gacattttaa ctggtgcagc taaaggtact caagtattcg gtcaagaccc
     8281 actatggctt gcatgggtaa cagaccttgt aaaccttaaa ggtactgata ctagtcaata
     8341 tcaacacttg ttagatacag tacatccagc tcgtttcaaa gttggacaaa tgatcggttc
     8401 attcggtatc ttgatgggtg tgattgttgc tatctaccgt aatgttgatg ctgacaagaa
     8461 acataaatac aaaggtatga tgattgcaac agctcttgca acattcttga caggggttac
     8521 tgaaccaatc gaatacatgt tcatgttcat cgcaacacct atgtatcttg tttactcact
     8581 tgttcaaggt gctgccttcg ctatggctga cgtcgtaaac ctacgtatgc actcattcgg
     8641 ttcaatcgag ttcttgactc gtacacctat tgcaatcagt gctggtattg gtatggatat
     8701 cgttaacttc gtttgggtaa ctgttctctt tgctgtaatc atgtacttta tcgcaaactt
     8761 catgattcaa aaattcaact acgcaactcc agggcgcaac ggaaactacg aaactgctga
     8821 aggttcagaa gaaaccagca gcgaagtgaa agttgcagca ggctctcaag ctgtaaacat
     8881 tatcaacctt cttggtggac gtgtaaacat cgttgatgtt gatgcatgta tgactcgtct
     8941 tcgtgtaact gttaaagatg cagataaagt aggaaatgca gagcaatgga aagcagaagg
     9001 agctatgggt cttgtgatga aaggacaagg ggttcaagct atctacggtc caaaagctga
     9061 cattttgaaa tctgatatcc aagatatcct tgattcaggt gaaatcattc ctgaaactct
     9121 tccaagccaa atgactgaag cacaacaaaa cactgttcac ttcaaaaatc ttactgagga
     9181 agtttactca gtagcagacg gtcaagttgt tggtttggaa caagtaaagg atccagtatt
     9241 tgctcaaaaa atgatgggtg atggatttgc agtagaacct gcaaatggaa acattgtatc
     9301 tccagtttca ggtactgtgt caagcatctt cccaacaaaa catgcttttg gtattgtgac
     9361 ggaagcaggt cttgaagtat tggttcacat tggtttggac acagtaagtc ttgaaggtaa
     9421 accatttaca gttcatgttg ctgaaggaca aaaagttgca gcaggagatc tccttgtcac
     9481 agctgacttg gatgctatcc gtgcagcagg acgtgaaact tcaacagtag ttgtcttcac
     9541 aaatggtgat gcaattaaat cagttaaatt agaaaaaaca ggttctcttg cagctaaaac
     9601 agcagttgct aaagtagaat tgtaatatac ttgaggttgg aagctgtatt ccaacctctt
     9661 attttgggag aaaagaatga aatttttaac actcaatact tacagttgga tggagaaaga
     9721 agcagaggaa aaattccaga ttttgcttga agatattctt gaaaaggact atgatttgat
     9781 ttgtttccaa gaaatcaatc aggagatgac ctcgtcagag gtggaggtta atgaccttta
     9841 tcaagctttg ccagcagctg agcctattca ccaagaccat tatgttagac tcttggttga
     9901 aaagttgtta gagcaaggga aaaattacta ctggacctgg gcttataacc atatcggcta
     9961 tgaccgctac cacgaaggtg tggctatctt gtctaaaaca cctattgaag ccagagaaat
    10021 tttggtttca gatgtggatg atccaacaga ctatcatact cgccgtgttg ccctagctga
    10081 aactgtagtc gatggcaagg agctagcagt tgccagtgtt catctctctt ggtgggataa
    10141 aggttttcaa gaagaatggg cacgatttga ggctgtcttg aaaaaattga acaagccact
    10201 tttactagct ggagatttta acaacccagc aggtcaggaa ggttaccaag ctattttagc
    10261 tagtccatta ggcttacaag acgcatttga agttgctcaa gagaaaagtg gtagctatac
    10321 tgttccgcct gaaattgatg gctggaaagg gaacactgaa ccccttcgaa tcgattatgt
    10381 ctttactacc aaagagttag cggtggaaaa tttacatgtc gtatttgatg gtaacaagag
    10441 tccacaagtg agtgatcact atggcttgaa tgctatatta aactggaaat aataactgaa
    10501 aagaggttgg aactataaaa ttccagcctt ttcttactag agaagctact ggaaatagcc
    10561 taaataagtg agactactgt aatggaataa aatatggtat aattgataag atagatagaa
    10621 tcgaggatgt tatgtcattt acgaaatttc aatttaaaaa ctatattaga gaagccttga
    10681 aggagttaaa atttacaact ccaacagagg tgcaagacaa gttgattcct attgttttgg
    10741 caggtcgtga cctagtagga gaatcaaaaa caggttcagg taagactcat actttcttgt
    10801 taccgatttt tcagcaatta gatgaagcta gcgatagtgt acaagcagtg attactgcac
    10861 cgagtcgtga gttggctact caaatttacc aagtagcgcg tcagatttca gctcactcag
    10921 atgtcgaagt tcgtgtggtt aattatgtgg gtggtacgga taaggctcgc cagattgaga
    10981 aattggcaag caatcagcct catattgtta ttggaacacc aggccgtatc tacgacttgg
    11041 ttaaatctgg tgatttagct attcataaag ccaagacatt tgttgttgat gaagcagata
    11101 tgaccttgga tatgggattc ttggaaactg ttgataagat tgctgacagt cttccaaaag
    11161 acttgcaatt catggtcttc tcagcgacta tcccacaaaa actgcaacca ttcttgaaaa
    11221 aatacttatc aaatcctgtt atggagaaaa ttaagaccaa aacggttatt tctgacacca
    11281 ttgataattg gttgatttcg accaagggac atgataagaa tgctcaaatt taccagttga
    11341 ctcagtcgat gcagccgtat ttggcaatga tttttgttaa cactaaaacg cgtgctgatg
    11401 aattgcattc atatctgact gctcaaggct tgaaggttgc aaaaatccat ggcgatattg
    11461 cccctcgtga acgcaagcga atcatgaatc aggtgcaaaa tctggatttt gagtatattg
    11521 tcgcaacaga tttggcagca cgtgggattg acattgaagg tgtcagccat gtcatcaatg
    11581 atgccattcc gcaagactta tctttttttg ttcaccgtgt tggtcgtact ggacgaaatg
    11641 gcctaccagg tacagctatt accctttatc agccaagtga tgactcggat atccgtgagt
    11701 tggagaaatt gggaatcaag tttagtccta agatggtcaa agacggggaa tttcaagata
    11761 cctatgaccg tgatcgtcgt gccaaccgtg agaaaaaaca agataaactt gatatcgaaa
    11821 tgattggttt ggttaaaaag aaaaagaaaa aagtcaaacc gggttataag aagaaaattc
    11881 aatgggcggt tgatgaaaag cgccgtaaaa ccaagcgtgc tgaaaatcgc gctcgcggtc
    11941 gtgcagagcg taaagctaaa cgccaaacat tttaatagaa attgttggag tactgagctc
    12001 caactttttt atttatgaga acgaactatc taaaccgaaa cactacatta aagactgcaa
    12061 attgcgatta aaaatggtat aatgataaag ttatatagtc ccgataagat ggtaggtatt
    12121 tattacgaag agttttccta tcagtagttt gcaattcgca aagaatgacg gcttcgaggt
    12181 cgctcgtctt tctacggttg ccgccatact gcggtcaccc tatgcgcctt actagcttca
    12241 gaaataaaaa agtatcgttt ttatttctga agctagtaac tcttagataa tggaaattcc
    12301 tatcagtact ttgtaactct ataacaatat tttttaaggg gggacatttt tatgtcagaa
    12361 cgtaaattat tcacgtctga atctgtatct gaggggcatc cggataagat tgcagaccaa
    12421 atttcagatg cgattttgga tgctatttta gcaaaggatc cagaggcgca cgttgctgct
    12481 gaaacagctg tatatactgg ttctgtccac gtttttggtg aaatttctac aaatgcctat
    12541 gtggatatta accgtgtggt tcgtgatacc attgcagaga ttggttatac caatacagaa
    12601 tatggatttt ctgctgagac ggtgggagta cacccatctt tggtggaaca atctcctgac
    12661 atcgctcaag gtgttaacga agccttggag gttcgtggaa atgctgatca agatccactg
    12721 gacttgattg gagcaggtga ccaagggctc atgtttggat ttgcagtaga tgaaacagaa
    12781 gagctcatgc cattgccaat tgcactcagt cataaattgg ttcgtcgtct ggcagaactt
    12841 cgtaagtctg gagaaattag ctatctccgt ccagatgcaa aatcacaagt tacagttgag
    12901 tacgatgaaa atgaccgtcc ggtacgtgta gatacagtcg ttatttctac tcagcatgat
    12961 ccagaggcca ctaatgaaca aatccatcaa gatgtgattg acaaggtcat caaagaagtt
    13021 attccatctt cttatcttga tgataaggca aaattcttta tcaatccgac aggtcgtttt
    13081 gtaatcggtg gtcctcaagg ggactcaggt ttgactggtc gtaagattat tgtagatact
    13141 tatggtggct actctcgtca tggtggtggt gccttctctg gtaaagatgc gactaaggtg
    13201 gatcgttcag cctcttatgc ggctcgctat attgccaaga atatcgttgc agcaggcctt
    13261 gctaagaagg cagaagtgca gttggcctat gctatcggtg ttgcgcaacc tgtttctgtt
    13321 cgtatcgata ctttcggtac aggaacagta gctgaaagtc aacttgaaaa agcggctcgt
    13381 caaatctttg accttcgccc tgcagggatt atccaaatgc tggacctcaa gcgtccaatt
    13441 taccgtcaaa catcggctta cggtcacatg ggacgtacag atattgatct tccatgggaa
    13501 cgtttggata aggtagatgc tttgaaagaa gcagtaaaat aagattttaa gaggggaacg
    13561 tcctctcttt tttatagttt ttaactatac tgggatactg ttctgaaaat ccattttgcg
    13621 aaagtagaga tttacatgta taatggattg aaactagaat agtacacctc aacttctaaa
    13681 acattgttag aaatcgattt gactgtcctg atcgatttct cctgttcttg tttcatttta
    13741 ctatatttct ttaaaaatga taaaggttga gatttctcct cgtaatagat aatcatgggg
    13801 atatttcaag ccaaagtttt attcgttatc acttgactat tgcaaggttt tctagatcaa
    13861 cagagtcatg gaatggactc atggttgaga tttctccttg ttgcttggac ttcattcaaa
    13921 agtctgttac ccaagccttg ttcaaacttc caatacacta gctgtttcca tagcatgact
    13981 tctgtactag actttctttt ccgaataaat agatagaacc acagaatcta gtaaacctag
    14041 aattaaaatt atggtataat attagcaata aaagaaatct ggaggattag aatcatggta
    14101 tcaacgaaaa cacaaattgc tggttttgag tttgacaatt gcttgatgaa tgcagcaggt
    14161 gtggcttgta tgacgataga ggagttagaa gaggtcaaaa actcagcggc aggaaccttt
    14221 gttactaaga cagcgacctt ggacttccgt caggggaatc ctgagccacg ctaccaagat
    14281 gttccacttg gttccatcaa ctctatgggc ttgccaaata atggcttaga ctattatttg
    14341 gattatcttt tagatttgca ggaaaaagag tcgaaccgaa ctttcttctt atctctggtc
    14401 ggcatgtctc cagaggaaac ccatactatt ttgaaaaaag tccaagagag tgattttcgt
    14461 ggtctgactg agctaaatct ttcctgtcca aatgttccag gtaaacctca gattgcctat
    14521 gattttgaga caacagaccg gattttggca gaagtgtttg cttacttcac caaacctctt
    14581 ggaattaaat tgccacctta ttttgatatt gttcactttg atcaagcggc agctattttc
    14641 aacaaatatc cgctcaagtt tgtcaactgc gttaactcta tcggaaacgg cctctatata
    14701 gaagacgaat ctgtcgttat tcggcctaag aatggttttg gtggaattgg tggagaatac
    14761 atcaaaccga ctgctctagc caatgttcac gccttttatc aacgtttaaa tcctcaaatc
    14821 caaattatcg gaacaggtgg cgttctgact ggtcgagatg cctttgaaca catcctctgt
    14881 ggagcaagta tggtgcaggt gggaacgacc cttcacaaag aaggcgtcag tgcttttgac
    14941 cgcattacca atgaactgaa agcaatcatg gtggaaaaag gctacgagag cttagaagat
    15001 ttccgtggga aattgcgcta tattgactaa attaaatcaa aaaatctgaa gaaaggagag
    15061 acgatgctag ccattgaaga aagtcagaag ttgactttat caaatttacc gagcctgagc
    15121 ctatttacag ggacagatca gggtcagttt gaagtgatga agagtcaaat gttgaaacag
    15181 attgggtatg attctgctga cctcaacttt gcctactttg atatgaaaga agtagtttac
    15241 aaggatgtgg aactggagtt ggtcagcctt cctttctttg cggatgagaa aatcgtgata
    15301 ttagattatt ttatggatat cacgactgct aagaaacgct ttttgacaga tgatgagctt
    15361 aagtcatttg aggaatacct tgacaatcct tctccaacaa ccaagttgat aatctttgca
    15421 gaaggaaagc tggatagcaa aagacggtta gtcaaattac ttaagcgtga tgccaaggtc
    15481 ttcgatgcag tagaagtaaa agaacaagaa ttgcgccagt atttccaaaa gtggagtcag
    15541 aaacaaggtc tgcagtttac caatcattct tttgaaaatc tcctcatcaa gtcggggttt
    15601 caatttagcg aaatccagaa aaatcttctc tttttacagt cctataaggc gaattctgtt
    15661 attgaggaag aggatattgt taacgcaatt cccaagacct tgcaggacaa tatttttgat
    15721 ttaactcagt ttattctgac taaaaagatg gatcaggcgc gcgatttggt gagagacttg
    15781 accttgcaag gggaagatga aatcaaactg attgcagtca tgctgggaca atttcggact
    15841 tttactcagg tgaagatttt ggcggagtct ggccaaacag aatcgcagat tgcaagtagt
    15901 ttaggtagtt atctgggacg taacccaaat ccttatcaaa tcaagtttgc attaagagat
    15961 tcgagaggac tttctttgag ctttctgaag caagctattt cctatttgat tgagacagac
    16021 tatcagatta agacaggtct ttatgaaaaa ggtttccttt ttgaaaaggc actcttacag
    16081 attgctagtc aggtcaattg acatttgttg aaactacaac ccgcgtcagg attatcttgt
    16141 cgtgggtttc ttgctgattt gcttatttta ttagaaagta tgtcagtgat ttccttatct
    16201 ataagcaaaa aacttgaaaa aagtgaatgt ttgcgttatc attttcatat agaaagaaaa
    16261 agaggtatta cagatggcta ttatcttacc agaacttcca tatgcatacg acgctttgga
    16321 accatacatc gatgcggaaa caatgcattt gcaccatgac aaacaccatc aaacttatgt
    16381 caacaatgcc aatgcagctt tagaaaaaca ccctgaaatc ggtgaagacc ttgaagcctt
    16441 gcttgctgat gtagaatcta tcccagctga tatccgtcaa gcacttatca acaatggtgg
    16501 cggacacttg aaccacgctc ttttctggga attgatgact cccgagaaaa cagctccttc
    16561 agcagaactg gcagcagcaa tcgatgcaac atttggttca tttgaagaat tccaagcagc
    16621 cttcactgca gcagcaacaa ctcgttttgg ttcaggttgg gcatggttgg ttgtcaacaa
    16681 agaagggaaa cttgaagtga cttcaacagc aaaccaagac acaccaatct cagaaggtaa
    16741 aaaaccaatc ttgggcttgg acgtttggga acatgcttac tacgtgaaat accgcaacgt
    16801 gcgtcctgac tacatcaaag ctttcttttc agtaatcaac tggaataaag tagatgaatt
    16861 gtacgcagct gctaaataat gatagttgga gggaagaatt gttcttctct ttttaggtta
    16921 taagattctg gtctgacaaa atcgtcagac ttttttcatt tttatgagaa acgtgctaac
    16981 tgctagaaat tatggtagaa taaagtatta agtaatcgtg gaaaaaggat atctatgcga
    17041 aaagaaattg cacctgaatt atacaactat aacaagtttc ctggtccgga gttccattta
    17101 cacggggata aggtcgaaac ggaagggata gctttttcct tggttgaaaa tatcaaggat
    17161 gcctttgatg tgacgacttt taatcagcgt ttttcagaag tcttaaccaa gtttgattat
    17221 atcgtggggg actggagcaa cgaacagctt cgcctacgag gtttttacaa ggatgaccga
    17281 acagaagaaa aacttgaaaa aatcagtcgt ttacaagact accttttaga gtattgtagt
    17341 tatggttgtg cctattttgt cttagaaaat gaagccccta agcgagcatc atttgacaag
    17401 aaaatgcgta agacggaaga agaaacacct tctagaaaag gaaagaaacc gactcaaact
    17461 aaacgaaagt cgaatgcaga taagaaaaat agacgtcgtc agaaagacca gcattctcag
    17521 aaagaggaca aggaacaacg tcattttgtc attcgtcaga agtgagtaga gaataaggag
    17581 aagaaatgaa accctcaatt catagtttga cacatcaaac catgcaggaa tgggtattgg
    17641 agcagggaga aaagaaattc cgtgcagatc aaatctggga atggctctac cgtaaacgtg
    17701 tgcagtcatt tgaagaaatg accaaccttt ccaaggattt gattgctaag ctcaatgacc
    17761 agtttgtggt caatcccttg aaacaaggta ttgtgcaaga gtctgctgat ggtacagtca
    17821 aatatctctt tgaattgcct gacggtatgt taattgagac tgtactcatg tgtcaacact
    17881 atggtttatc tgtctgtgtg accactcagg tcggctgtaa tatcggttgt accttctgtg
    17941 cctctggttt gattaagaag cagcgtgacc tcaataacgg tgaaatcgta gcgcaaatca
    18001 tgctggttca gaaatacttt gatgagcgtg gtcaggatga acgcatcagc catatcgttg
    18061 tcatgggaat cggtgagccc tttgataatt acaacaatgt cttgaatttc tttcgtacta
    18121 tcaatgatga taaaggaatg gctatcggtg ctcgtcacat cacggtttca atctcaggtt
    18181 tggctcataa aattcgtgac tttgctgatg aaggggttca ggtcaatctt gccgtgtctc
    18241 ttcacgcacc caacaatgaa cttcgttcaa gtatcatgaa gattaaccgt gcctttccga
    18301 ttgaaaaact ctttgctgct attgaatact acattgagac aacaaaccgt cgtgtaacct
    18361 ttgaatatat catgcttaat gaagtcaacg acggtgtgga acaagccttg gaattggctg
    18421 aattgctcaa gaacatcaag aaatcgtctt atgtaaactt gattccttat aacccagtta
    18481 gtgagcatga ccaatatagc cgtagtccca aagagcgcgt gttggctttc tatgatacgc
    18541 ttaagaaaaa agggggcaac tgtgtggttc gtcaagagca tggtacagat attgacgcag
    18601 cttgtggaca attgctcttt aacacaatga aacgtgaccg ccagaaggca gtcgcagcgg
    18661 taaatcctta atgatgaaga agacttataa tcatattttg gtctggggag tcattttcta
    18721 tagcatttgc attgtctatt tttgctttac tcctcaagaa caatctaccg tgggagtggg
    18781 aactccagat attcagcatc ttggacgcct ggtttttctt ttgactcctt tcaattctct
    18841 ctggaaactg ggcgaagtga gtgacattgg acaattatgt tggatttttt tacaaaatat
    18901 cctcaatgtc ttcttgtttt ttcctctgat tttccaactc ctttatctat ttccaaattt
    18961 gcggaaaaca aaaaaggtcc ttctttttag ttttcttgtg agtcttggaa tcgagtgtac
    19021 gcaattaatc ttggactttt tctttgattt caatcgcgtc tttgagattg atgatttgtg
    19081 gaccaacact ttgggtggct atctggcttg gctcctttat aaacgattac ataaaaacaa
    19141 gataaggaat taaaatgagt attttagaag ttaaaaatct gagtcacggt tttggtgacc
    19201 gtgcaatttt tgaagatgtg tccttccgtc tcctcaaggg ggaacatatc ggcctggtcg
    19261 gtgccaatgg tgaaggaaaa tcaaccttta tgagtatcgt gactggtaaa atgctgccag
    19321 atgaaggaaa ggttgagtgg tccaaatatg tgacggctgg ttacttggat cagcactctg
    19381 tccttgctga aagacagtcg gtgcgtgatg ttctccgtac ggcttttgat gagcttttca
    19441 aagctgaagc tcgtatcaat gacctctata tggaaatggc tgaagacggt gcggatgttg
    19501 atgctctcat ggaagaagta ggagaacttc aagaccgtct ggagagtcgt gatttctata
    19561 ccttggatgc taagattgac gaagtagcgc gtgctcttgg tgttatggac tttggcatgg
    19621 atacggatgt aacttctttg tcaggtgggc aaagaaccaa ggtgcttttg gcaaaacttc
    19681 tccttgaaaa gcctgatatc ttgctgttgg acgagccgac caactacttg gatgctgagc
    19741 atattgattg gctcaagcgc tatctccaaa actatgagaa tgcctttgtt ctcatttcgc
    19801 acgatattcc attcctcaat gacgttatca atattgtcta tcatgtggaa aatcaacagc
    19861 tgacgcgtta ctctggtgac tactaccagt tccaagaagt ttatgctatg aagaaatctc
    19921 agctagaggc agcctacgaa cgccagcaga aagagattgc agacctcaag gactttgtgg
    19981 ctcgtaataa agcccgtgtt gcaactcgta atatggctat gtctcgtcaa aagaaattgg
    20041 ataagatgga tattatcgaa ctccaaagtg agaaaccaaa accatccttt gatttcaaac
    20101 cagctcgtac accagggcgc tttatcttcc aaaccaagaa cttgcaaatt ggttacgacc
    20161 ttcctcttac taagccttta aatcttacct tcgaacgcaa tcaaaaggtt gcgattattg
    20221 gtgctaatgg tattggaaaa acaactctct tgaagagtct cttgggcatt atctcgccaa
    20281 tcgctgggga agtggagcgt ggagattatt tagaacttgg ttattttgag caggaagtag
    20341 aaggcggtaa tcgccaaact cctcttgaag ctgtctggaa tgcctttcct gcccttaatc
    20401 aagcagaagt ccgtgcagcc cttgcccgtt gtggtttgac aaccaaacat attgaaagcc
    20461 agattcaagt attatcaggg ggagagcaag ccaaggttcg tttctgtctc ttgatgaatc
    20521 gtgaaaacaa cgttttagtg ctggacgagc cgaccaacca tttggatgtg gatgcaaagg
    20581 atgagctcaa acgcgctctc aaagaatata ggggatctat ccttatggtc tgccacgagc
    20641 cagactttta tgaaggctgg atagaccaaa tatgggattt taataattta acttaagaat
    20701 gagagtaaaa gaaatacagt accgaatgtg gatactgtat ttttttggtt tttaagattt
    20761 aaaatcgtag tctttcacca cttcgatgct gtcgattgtg atagcagtag ttggcttgtc
    20821 tttttcatct ttttcggcct tagcaatctt atccacaaca tccataccgt caatcacttg
    20881 accaaagact gggtgtttgc catctagact agggtttcca ccttctttgt aggcttcgat
    20941 aattttctgt ggatacttgc ttgtagggag tttagaagag gtatctgtag agctttggtt
    21001 gatgaagaac tggctgccat tggtgtttgg ttgaccagta ttagccatag caagagcacc
    21061 acggatgtta tacaaataag gagtaatctc gttcttgaaa ccagttcctt tgtctttagt
    21121 cttatccttg tcatgccaga tggactgacc acctgtaccg tccccttttg gatctccagt
    21181 ttggaccata aagccatcga tgacacggtg gaaggtaata ccgttatagt agccttcttt
    21241 ggcgtgagtg aggaaatttt caaccgctag aggagcgagt ttagggaaga gtttaatgcg
    21301 aatatcacct tggcttgtgt ggagaatcac ttcggcttca tcttcagcaa cttccttaga
    21361 tagttgtggg aaattggcgt tttcgtttgt taaagcatcg tttaactcct tggcagattg
    21421 ggcagctact ttggaacttt cttcagcagc aagactggaa tcaacataat catcaccacg
    21481 cagactgcgt tggacgctgc tacacccagc tagggctaca gtagacagta aaagaagggt
    21541 tgctagtttt ttcattctga tcctctcaaa aattcattta taccattgta ccctaaaaag
    21601 aagtggattt caaatattag tagtttacag aactggctta gataatagtt gggatttcat
    21661 catcatcttg aaaatcttca acttcttcaa cttcttcccc agtaaatggt ttctgaaaag
    21721 aacttagtat aaaacgggca attggttcaa caattaggaa atttagagga agagctgcaa
    21781 taaagtttac gaaccaggcg cttagatagg tattgggtgt gatagcaatg ccattgtaaa
    21841 aaagtccata gaaggacatg aaagtgacca gctaattctt cttctgaaaa atgctcatga
    21901 agggcttgat ccaggtcgca agatttcatt ttagaaagtc cagtaactcc cttcttcttc
    21961 aggatattct ttttcatggt attatttaga tggtcaagtg agtcaaaaga agtttcgaca
    22021 agagcatacc ctttttctat cagagttttt agatgtttag gggcatcaat accataagtg
    22081 tactcaaagt attttggaaa ccagatctta agaaagctcg taaagctagc cagttctcta
    22141 aacgctaaga actagctaca acacagcatt tacaacactt catggttcac accatggggt
    22201 gctttttaat gattttaagc aaaattcaca cttaattgaa agttatttaa attagatgaa
    22261 aatttatttt ttgaaaaagc gggaaaacat tgattctaag cgaattttga atcatattcg
    22321 aatgggagtt tttaaaatca tgtttcagtg gtaaaagtac caaactggat tctccatagt
    22381 aaaatgatat ctcctgctag tgaatcatct actaataagt ccatatttcg cttgggaacg
    22441 ggcttgggac ttagaagcca agtatccaac tctcgttcag gcgatatgaa gggtttgact
    22501 tggtgttctt tataaaattt ttctaaaata gtattcacgg atagcatctt tcaaacattt
    22561 atttcctatt ctaacaaatt tctaaatact ttaagaaatt tatagtctgt caagtttttt
    22621 tcttgacaca tgccagaaat ctgctataat agaacatgtg ctaaatagct cagctatttc
    22681 accgaaataa aaaattaaag aaatgagact ttaaaaatgg cagttaaaat ccgtttgact
    22741 cgtatgggtt ctaagaaaaa acctttctac cgtatcaacg tagcagattc acgttcacca
    22801 cgtgacggac gtttcatcga aacagttgga acttacaacc cacttgttgc tgaaaaccaa
    22861 gtaactttga aagaagaccg cgttcttgca tggttggcta atggagctca accttcagac
    22921 acagtacgta acatcctttc aaaagaaggc gtattgaaaa aattccacga ttctaaattc
    22981 tcaaaataag tttaaagtag gttgacagat ggatacgatt gaaaatctca ttattgcgat
    23041 tgtgaaaccc ttaatttcac aaccagatgc cttaactatc aagattgagg atacaccaga
    23101 atttttggaa tatcatttga atcttgatca aagcgatgtg ggtcgtgtaa tcggtcgtaa
    23161 gggtcgcact atttctgcga taagaacgat tgtctactct gtcccaactg aatacaaaaa
    23221 agtaagaatc gttattgacg aaaaataaga agggcgggac ggatgtctcg cttttttgtg
    23281 tggaatagaa g
//
LOCUS       DAVBNZ010000031        22634 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000031 DAVBNZ010000000
VERSION     DAVBNZ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.031"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(339..1319)
                     /locus_tag="VQ860_001277"
     CDS             complement(339..1319)
                     /locus_tag="VQ860_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET3119704.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVDDQVYNWLCGSEIPFKYLK"
     gene            complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ860_001278"
     CDS             complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ860_001278"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET3119705.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKYLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3669..4772)
                     /locus_tag="VQ860_001279"
     CDS             complement(3669..4772)
                     /locus_tag="VQ860_001279"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET3119706.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4762..5130)
                     /locus_tag="VQ860_001280"
     CDS             complement(4762..5130)
                     /locus_tag="VQ860_001280"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET3119707.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5169..6200)
                     /locus_tag="VQ860_001281"
     CDS             complement(5169..6200)
                     /locus_tag="VQ860_001281"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3119708.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6202..7233)
                     /locus_tag="VQ860_001282"
     CDS             complement(6202..7233)
                     /locus_tag="VQ860_001282"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3119709.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ860_001283"
     CDS             complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ860_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET3119710.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQSMIKRTLERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9973..10262)
                     /locus_tag="VQ860_001284"
                     /pseudo
     CDS             complement(9973..10262)
                     /locus_tag="VQ860_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10290..10922)
                     /locus_tag="VQ860_001285"
     CDS             complement(10290..10922)
                     /locus_tag="VQ860_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3119711.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10926..11567)
                     /locus_tag="VQ860_001286"
     CDS             complement(10926..11567)
                     /locus_tag="VQ860_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119712.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYILLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11560..12351)
                     /locus_tag="VQ860_001287"
     CDS             complement(11560..12351)
                     /locus_tag="VQ860_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119713.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            complement(12536..12871)
                     /locus_tag="VQ860_001288"
     CDS             complement(12536..12871)
                     /locus_tag="VQ860_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119714.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(13011..13346)
                     /locus_tag="VQ860_001289"
     CDS             complement(13011..13346)
                     /locus_tag="VQ860_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119715.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13437..14747)
                     /gene="der"
                     /locus_tag="VQ860_001290"
     CDS             complement(13437..14747)
                     /gene="der"
                     /locus_tag="VQ860_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET3119716.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14761..15474)
                     /locus_tag="VQ860_001291"
     CDS             complement(14761..15474)
                     /locus_tag="VQ860_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET3119717.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDVKPRLPLENVVFEEEYQEQSTETIQAYDRVQADYAGGRATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15471..16367)
                     /gene="dnaI"
                     /locus_tag="VQ860_001292"
     CDS             complement(15471..16367)
                     /gene="dnaI"
                     /locus_tag="VQ860_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET3119718.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16368..17537)
                     /locus_tag="VQ860_001293"
     CDS             complement(16368..17537)
                     /locus_tag="VQ860_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET3119719.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17538..18011)
                     /gene="nrdR"
                     /locus_tag="VQ860_001294"
     CDS             complement(17538..18011)
                     /gene="nrdR"
                     /locus_tag="VQ860_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET3119720.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18151..18516
                     /locus_tag="VQ860_001295"
     CDS             18151..18516
                     /locus_tag="VQ860_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3119721.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18521..19216
                     /locus_tag="VQ860_001296"
     CDS             18521..19216
                     /locus_tag="VQ860_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119722.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19233..20000
                     /locus_tag="VQ860_001297"
     CDS             19233..20000
                     /locus_tag="VQ860_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119723.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20353..21552)
                     /locus_tag="VQ860_001298"
     CDS             complement(20353..21552)
                     /locus_tag="VQ860_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3119724.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21549..22442)
                     /locus_tag="VQ860_001299"
     CDS             complement(21549..22442)
                     /locus_tag="VQ860_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119725.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
BASE COUNT         6645 a         5104 c         4193 g         6692 t
ORIGIN      
        1 tttttgaaaa gtattaacac ctacagacaa gcctgacgat agcaagaact accctactcg
       61 ataggtatcg gcttttgctt tctgaaaaaa attattttaa gcaatttgac aaatctagca
      121 acaaaaaatt ttataaatac aatagattga aactagaata gtacaccttt gcttctaaaa
      181 cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgtttttat ttcattttac
      241 tatatttcca tgataaaacg catagtatca agttttctta atcccctgat actatgcgta
      301 tttgtaattt ttaagatttt gtgcttagag tcgactcctt attttagata tttaaaagga
      361 atctcactcc cacagagcca gttgtagact tggtcatcga caaatacatt catggcttcg
      421 tgagcatact caggcatgat gcgataggtt ttatcgcagg tcagacgatt ataaatcgca
      481 aactgggtaa tgggatagca aacatcgtcg tccaagcccg taatcatctt aacctcacct
      541 tggatacgat gggcaagatt tttgacatcg atataggcaa gggtcgccat gatttcctcc
      601 tctgtttcat ggaaggggtc gtgaaacttg aaataacgga aaagttcgtc gtaagcctcg
      661 ctagtattac caatctcaat cacccgtctg aagtctgaca agaagggata aatggcaact
      721 gttttctgaa ttcgaggatt gagcgctgct gcaactagag ctagagcccc tccttgtgag
      781 gcaccatagc tagaaagacg cttctcatca acctgagaca gactagcaac aatttcgacc
      841 aactggtaaa tatccagata aacatcctta taaaagaggt ggtcccgacc ttccatagca
      901 ccacggataa tatgcccctt cacggtattt cctaaaggag aacgcaagcc gtcttgtgag
      961 taacctgact ggccccgcac atccatggaa acaacaccgt aaccagctac ggtgaagccc
     1021 agcatgtcgg cccagtccca gccacgtccc atataaccat gaaaatggaa gattagtgga
     1081 accttctcct cactctttgg aagaacaatg cgtgcataga cctttccttc cttgcttcct
     1141 tcaaatgtta actcatagca cttgacttga ggaatgtgga aatctctttc ctccaagtgg
     1201 taggatggaa gcgtggaaac atttttcact tccccatccc agaaagcatc aaagtcttcc
     1261 ggaacctcat cccttcctct ataggtctta atttcttcta gcaaagctgg atttttcata
     1321 gcatgctcct tttattttgt aatcgttacc acaactgtag catatctatg taatcaatgc
     1381 aagaaagaag gataaataga aagtgaattt agattcttta cttttaggat gataggctga
     1441 aagtagtttt agaaacgaaa aagagcattt cgctctctct tctgtttata ctagtttttt
     1501 gcttccttct tttggaaagt ggtttggtaa tttactttaa tcgttactgt catatgagag
     1561 tcctcgtttc tttttgatga ctttagtata agagccaaac ctaaaaacta gcttaagttt
     1621 tccttagaga aagcttaatc cagatgttct ttcttttcca gatgaagggc aatcatgcgc
     1681 cactctggat cttcttgcca agcttctata gaactaatgt agctagcaac ctttcttgct
     1741 tcttctaaaa tcggaaaatc ttcgataata tcagccactt ggaactctgg aagtcctgac
     1801 tgtctggttc caaaaatctc accagaacca cgcattttca aatcttcctc cgcaaggaca
     1861 aatccattgg tcgtttctgt catgatacgc atgcggtctt tcccagaatc cgtcttggga
     1921 ttagcaacga gaacagcgta ggactgcttg tccccccgac cgacacgacc tctaagctgg
     1981 tgaagttgac tgagaccgaa gcgatcggca tccatgataa tcatgacagt cgcattggga
     2041 acgttgaccc caacctcaat aaccgtcgtc gaaaccagaa tatccgtctt tctctccttg
     2101 aaatcctgca tgatctggtc tttttcgtca ctcttcatcc taccatgtag aagagccacc
     2161 tctgccttgc ctgcaaaatg agtcgtcaac tcctctgata aggcaatggc atttttcaaa
     2221 tctagagctt ctgattcttc aatcaaagga gagatgacat agacttggga acctttttga
     2281 atttccccct ctaaccaagt caagacctga ggtagttgct catgtttgat ccagcgcgtc
     2341 acaataggct tccgacctgc tggcatctgg tcgataatgg aaacatccat atctccaaag
     2401 gctgtgatgg caagcgtccg tggaatggga gtcgccgtca tcatgaggac atctggattg
     2461 tcaccttttt cccgtaaaat acgcctttgc cctacaccaa aacggtgctg ctcatcgata
     2521 ataatcaaac caagacgagc atactccacc ccatcttgta tcagagcgtg agttcctata
     2581 atcaaatcag cctcaccctt ggcaatggtc tccaagactt ctctcttttc tgcagctttc
     2641 aaggaacctg tcaagagagc cagtttcaaa ttgggaaaaa ggttctgtaa actctcaaag
     2701 tgttgctctg cgaggatttc tgttggtacc attagggcag cctgataacc tgctgtcact
     2761 gccgcaaaca tggccaagcc agcgactacc gtttttccac tccccacatc cccttgtagg
     2821 agacgattca tgtggtggtc ggacttcata tcagttaaaa tttcctgcaa actcttttcc
     2881 tgagcttggg tcagggcaaa aggaagactt actttaactg ctgtcacttt ttcctgagac
     2941 caattcagaa ccagaccact tccctgaact ctattttcag acttgagcat ctgcagctgc
     3001 atttggaaat aaaagagttc ctcaaacttt atacggcgaa gagcctgctt gtattctgcc
     3061 aaatactttg gaaaatgcat agcacggact gcctgacaac gggacatgag tttgtatttg
     3121 tctagtaaag actggggcag attttcttct atcaagaggt ccagtccctg atcaaaagcc
     3181 gtcttgatga ccttgaccag actggcctgg ctgattccct gagccagacg atagacaggc
     3241 tggaggtcat cttctacctg agccagaacc ttcatcccag tcagactagc cttagcgcgg
     3301 tcccattttc caaagacagc aagggttgct cccaactcta ttttatcagc cagatagggc
     3361 tggttaaaga aattcaccgc aaaaacgacc tctccctgct tgagactaaa acgcaggcga
     3421 ttgcgcttga aaccataata ctggacacta gcaggagtca ctacctgacc agaaagaact
     3481 gccttctcac cgtcttccag ctccagcacc tgcttggttt tgaagtcttc ataacggaaa
     3541 ggaaagtaga gcaagagatc ttgcaagttt tcaattccta gtttggcgta tttttctgct
     3601 gactttggtc ccacaccagg caagacatgc aagggttgat gtagattcat gctccactcc
     3661 tttcttttct aataatattc tctcggaata cggtcgctga ggaggcaaac cacctcatag
     3721 ttaatggtta cgcggtaggt cgctacctga gttgcagtga tttccttatc cccattggag
     3781 ccaatcaagg ttaccttggt tcctagcgga taaagcttag gcaatcgaat agtgatttgg
     3841 tccatcgaaa ccctgccgac aattgggcaa gcttggccat ctaccaagac agagaaattt
     3901 tgcatgtctc ttgtccatcc atctgcatac ccgattggca cggtcgcgat gacttgctcg
     3961 ctatccgctt gataagttgc tccatagccc atgcaagctc cagctggaac tgtcttgaca
     4021 tgaaccagag cagactccaa ggtcaaggcc ggtatcaaat cataaggcaa atccaagacc
     4081 gctccacttg gattgaggcc atacatggca tctcccatac gaaccgcatt gaaaatagtc
     4141 tctacatgcc aaagagtcgt tgcagaattg ctagcatgaa ccagctctgg aacttccttc
     4201 atactagcta aaatagtttt aaaccgttct aactgggcat taaaatagtc atctgattcc
     4261 tcatcagcag tagcaaagtg ggtaaagatt ccttcaacac aaacaccgtg ttgttggagc
     4321 aaatcttgag cctgctcaac ctcacttgcc tctctaaaac caatccgtcc catccctgaa
     4381 tcaatcttga ggtggactgt caatccagtt aggtccactt ccttatctaa gagtgcttga
     4441 atccactcca gtccagccac tgtcaaggtg aagtcatatt ctttagctag agcaacagct
     4501 tcgatttcag aaactcctaa aatgaggatt ggcttgctga gtccagcttg tctgagttca
     4561 atggcttcat cgatattgga aacgcaaaag ccatcaacat catcttgaat tgccttggca
     4621 acggcaacag ctccatgacc ataagcattg gccttaacca cagccaactt gagcgttcct
     4681 tgagggatat gagcccccat ttgctgaata ttttgtcgaa tagctcccag atgaatcaga
     4741 gccttggttg gtctatgtgg actagctttc atgattttcc tccaaaatga cactggctgt
     4801 cacaaactga tcggtgtggc tgatagacag ccaaatcttt cctgaaaatg gtgcctgact
     4861 aaaataaggc gccccacgtt cattgttcaa gacttccaaa tcctgaaaac cgagcttgct
     4921 aatgcccgtt cccatagcct tggaaaaggc ctccttagcc gaccagcgac cagctaaata
     4981 ttctatttgc ctgcgtcctt tgagactggt gaagcgctcc atttcctgag cggtcagtac
     5041 acgcttagca aatccttcat gtcgtgtaac tgcgctttct atcgaagcca attcttcaat
     5101 gtcaattccg tgtccaacta tcattctcat caaaaggagt tgagattccc caactccatc
     5161 cttttcactt attttgtcaa ggtaacataa atctcttcta ccaaggcctc tgtattttcc
     5221 caacctaggc aagggtcagt aatagagcaa ccaaagatct ctggttggtt ttgacgacca
     5281 tctgctaggt aagattcaat cataaatcct cgaaccgtct ttttaatttt ctcattccaa
     5341 tcacgattct gcaaggtctg gcgaacaatt cgaatctgct ccatatattg cttgcctgag
     5401 ttatcatggt tggtgtcaat gaggataaaa ggattttcaa gtcccatggt ttcatagcgt
     5461 tcaatggctt ggagtagatt ttcatagtag taattcggca tataattgcc atactcgttg
     5521 actgctccac ggaggataac atgggccaaa ggattacctg atgtctcaac ttcctgccca
     5581 tgataaagga aggtttgctt gttttgagca gcatagatgg cgttaaacat aacacccaaa
     5641 tttcctgagg ttggattttt catccctact ggtgcatcaa tcccagaagc cacaaagcgg
     5701 tgctcttggt cttccacaga acgagctcca acggcatggt agctgaccaa gtcatccacc
     5761 aagatcagat ttgacggata aagcatctca tctgccgttg tcaaaccagt ctctgtaatc
     5821 acgcggtagt gcaactggcg cacagcctgc aagccattaa tcaggcttgg agccttagaa
     5881 gtatctggct ggtgaactaa tcctttatag ccgtctccat tggtacgagg cttagcagta
     5941 tacacgcgca tgaccatgaa aatcttatcc gctaccttct tttgcaaggc agataaacgg
     6001 cgagcatatt ccaagaccgc ctcttcatta tcagaagagc aaggaccaat caccaagaga
     6061 atacggtcat cttcccctga aataatatct gccaattccc tgtcacggct ttccttgagt
     6121 ctcaaggctt ccgcagacaa ttgggtttca gccttgatga cttccatatc gatttcttga
     6181 cctttttcaa taaatgccat cttattctcc taacgttttg taaatttctc tgacaagagc
     6241 ttctgtgtta tcccaaccca ggcaagggtc tgtgatagac ttaccaaata cttctggctc
     6301 attttgtcga ccatcttcca gataagactc aatcataaaa ccacgaacga actgcttaat
     6361 tttttcattc caagcacggt taatcaaggt ctggcggaca attcggatct gttcaatata
     6421 ctgcttacca gaattgtcat gattggtatc aatgatgata aaaggatttt ccaagcccat
     6481 tttctcatac tgggcaatgg tatcaattaa attgtcataa tagtagttgg gaatattttt
     6541 tccatactca ttaagagcac cacgaagaat agcgtgtgaa agcgggttcc cagttgtttc
     6601 tacttctttt cctaagaaaa ggaaactttg tttgttttga gcagcataaa tcccattaaa
     6661 catgacattg agatttccag aggttggatt tttaaaacca gtagaaaatc ctgccccact
     6721 tgccacaaag cggtgttgct ggtcttcaac tgaacgggca ccaactgcca tgtaagaaat
     6781 caaatcatct acaagcggaa ggttttcagg ataaagcatt tcatcagcag ttgtcatccc
     6841 tgtttctgtg atgacacgat agtgaagatg gcgaacggct ttgattccat tgataagact
     6901 aggcgcttct gtcgcgttag gctggtgaat caagccctta tagccatctc cgttggtacg
     6961 gggtttggca gtataaacac gcataaccat aaagatacga tctgccactt cttcttgtag
     7021 gactgccaaa cgcttagcgt attcaaggac agcttcttcg ttgtcagatg agcatggccc
     7081 gattaccaag agaattcgct ggtcttctcc acgtataatg gcttctagct cttgatctcg
     7141 ctgtgatttc ctctccaaag cctgaccttc taattttgac aaggcacgaa cttcttctat
     7201 atttatttta gagctttttg ctgtaaatac cataactcat ctccttataa agcaaacgga
     7261 tacccagtaa aaatttactt ttcacaagat atccgcctct aaactatctc attttattgt
     7321 cttttaccgt gacagttttt aaatttctta ccagaaccac atgggcaaag ttcattgcgt
     7381 ccaatctggc tcaaatccaa atcttctggc atacttgctt ggtgagcagc gatattgcga
     7441 gtcgctgttg tactgatatg acgttctgcc tgtggtcttt cttgttcatg aatttgtgct
     7501 ttcatcatca agcgtgtcac atcaaactca atcgaaccaa tcatatcatt aaacatacgg
     7561 aaaccttctg cctgatactc aacaacaggg ttgttctgag catagccacg aagtccaacc
     7621 gcgttacgca attgatcaag ggcatcgata tgatctgtcc acttgttatc caccactcgt
     7681 agaatcaaaa ctttttggaa ttctttaact gcttcttcat cgcgtagttt tgaaacctga
     7741 ctatcgtaaa ccttcaaggc acgttggaaa agctcttcct tgatggcctt atcagacaag
     7801 cctgacaagt cttccatcgt aatagaatct tcaggaagca agttgtactt agcaaagttc
     7861 aaaattgcct ctagtttttc atcttgtttg gcacgcgcat gaccatcaac gacacgttca
     7921 agcgtgcgct taatcataga ctgaatttca ggtgccaagt cacggtctgc agtaatgaca
     7981 tcataacgtt gagtatagat aatctcacgt tgttcacgca tgacatcgtc gtattgaagg
     8041 acttgtttac gggtatcgta gttatttcct tcgacacgtt tctgagctgc ttcaacctga
     8101 cgcgtcaaca tgcgagactc aatcgcctct tcagacatgt tcaagcgttc aaagattccc
     8161 ttcaagcgtt cagaaccaaa acgtttcatc aaatcatctt caagagatag gtagaattgt
     8221 gactcacctg gatctccttg acgacctgaa cgtccacgaa gctggttatc gatacgacga
     8281 ctttcatgac gttctgtacc aataacacaa agtcctccaa gttcacgaac accttcacca
     8341 agcttgatgt cggtaccacg acccgccatg ttggttgcga tggtaacggc accacgttga
     8401 ccagcattca tgatgatttg ggcttctcta tagtggtttt tggcattcaa gacttcgtga
     8461 ggaacaccag ctgcaaccaa tttcttagaa atgtagtcac tagtttcaac cgctactgta
     8521 ccaaccaaga caggttgacc cttttggtaa cgagccttaa cgtcttcgac aaccgcttta
     8581 aacttagatt ctatacttgc ataaagaagg tctgagtggt caatacgttg aacaggacgg
     8641 tttgttggga ttggaataac acgaatgttg tagatttcac ggaattcttc ttcctcagtc
     8701 ttacctgtac ccgtcatacc agacaatttc ttgtacatac ggaaaaggtt ttggtacgtg
     8761 attgaggcag atgtcttggt ttcatcctgg attggcacac cttctttggc ttcaatagct
     8821 tggtgcaatc catcagaata acgacgacct tccatggtac gacctgtaaa ttggtcgaca
     8881 atcaagattt cttgctcttc gctcaccaca tagtcaatat cgagaagcat gatgtagttg
     8941 gcacgaaggg cgttatcgat aaagtgggtc aaagccacgt tttcgatgtc atagaggttt
     9001 tcaagtttga agtagctttc agccctgtca atccctgaat cagacaaacc aatagtctta
     9061 gactgcacat cgatgatgta gtcatctttg ttcaaagatt ttacatagtg gtctgccatg
     9121 tgatacaact gactggtttc aaccgcattg gcacctgata caatcaaagg tgtacgagcc
     9181 tcgtcaatca agatagagtc aacctcatcg accaaggcat agttaagcgg acgttgtacc
     9241 atgttttcag cgcgaacgac catattgtca cgaaggtagt caaatccgat ttctgagtta
     9301 gttgagtaag taatatcaca ctcataggct tcttttttct ccattggaga tttggtagcc
     9361 aagttaatcc ctactgacaa accaagccaa gagtacaatt cacccatctc agtcgcgtca
     9421 cgttctgaca ggtattcatt aaccgtaact acgtgaaccc ctttacctga aagggcattg
     9481 aggtataccg gcatggtcgc agtcaaggtt ttcccttccc ctgtacgcat ctctggcacg
     9541 tcaccatggt gaagaacaat cccccccatg acctgaacct tataagggaa gagacctagg
     9601 acacgtttgg caccttcacg gacaaccgca aatgcttcgt aaagcaatga atccagtgat
     9661 tctccatttt gataacgttc cttaaattca actgtttttg cttttagttg gtcgtcagtc
     9721 aaagcagcca tttggtcttc gtatttgaaa accttgtcag ccatcttttc cagacgacgg
     9781 atttctcctt tatcattttc gataattgtt tttaaaatat tagccatgtt tttccttact
     9841 ttaaattccg aatattttag aatgttcctt taattttagc acaattactg attattttca
     9901 aggaagaatc cccattttga aaaggaaaaa gaggttagtt tccaagctaa cctctctgac
     9961 ttttatgata ctttaattgc caagaatcgg caaaatagca aataggataa ataagttaat
    10021 ccaaagagaa agacagcaga tcaatccaaa aacaaagaga ctgactttct tggacagcaa
    10081 ggccatcaaa atggacagaa tgccaaaaac tagcaagact ttctgtatgc tgaagaggtc
    10141 aatcttcccc cccccagaat cggactgccc caaggaagaa agaagaaagc aatccagatc
    10201 aacagaacta aaccaatata gaccttagaa tagcgtgtaa taaatgattt tagatgtgcc
    10261 ataagccatc tcctaggatt gtatatcctt tacatttgta tatgtccatt ttcgacaact
    10321 aatacatctg tacaaaggtc tgaaatatct tccgatatgt gcgacgtcag gataaccaga
    10381 ccattttctt ttttcaggta agataaaatg acctgtttgg ttaacctcac acttttctca
    10441 tccaaagcat tcataggttc atcgagaaag agtatagaag gagaggaaat aaaggcttga
    10501 atcaaggcca ttttttgctt tgttcccaag gataaatgcc ggtattcaac gtcttcaaat
    10561 tcctgtaaat catagtattg aatccaatag gcaattcttt tttccgtaac tttagatgaa
    10621 aaatacctta acagttccaa attttctctc agggataaat gagataaaaa ctcgactttt
    10681 tcaattaaaa ttcctgcatc ctgaatataa tgatttttta tcccgtaaac tttaccatct
    10741 tgaagaactt ttcctttgtc aagcttaata taaccagcaa gtatctttaa aagaaccgtc
    10801 ttgccagatc cattatcacc tttaagtcca taaatttttc ctgattgaaa caccaaattc
    10861 aactgattta aaataggtct tttcccataa attttctgtc catttataat ttcaagtctc
    10921 atcgtttatc ctttcttaaa tttctcttcc aagcgactaa gaatcaacat aactaataag
    10981 cttaagagta ctaaatacac tgttacaata tgatccatca tccattcttg tcccacaaat
    11041 gccaaaaaat agagaaaaaa agaaaaacca gcgcccgcac taatcagtgc tatcagataa
    11101 gacagtagta tgtacaacat cattaactga gcaagtaaaa agaaaagtgc gactgttttg
    11161 aaatgaattc ctagcggaag taaaccaaga aaccagacaa acaaatcttg agtaaaaaat
    11221 ttagaaatga caaccaatcg tttccttgta taatcgaaaa aggagcttga ttgatagcga
    11281 atcaagtgat ggtaatggtc tgccaaatca ctttcaagta aaatgacaga gagccatcct
    11341 accatgaaaa gcgaaaggtt taacaagagt ttggggattt ctaaattcgc ttcagaatag
    11401 tcattatagg aaaaaattga aatcaattct ctcttgaaaa agataacagc atcctgcttt
    11461 tgaaccgctg ttgacaatag atagtttatc aaaatcatca tcagaactat acgaagtagt
    11521 aaaacgatct ttctctttag ccaaatattg ttaaaattct taaacattat cttcatattt
    11581 tttaagtacc atataaggga caacataaag gatataagga gtaaagagtt tcatcaaact
    11641 tacatcccca tagctagctt gcatcaaact cgtcatagga accatatagt aaggcaaggc
    11701 actatagagc agcatagaac caagccaaag aaacatcaaa taggtgattg ccgaacgagt
    11761 cacattcccc acataatcaa ctatttgtaa aaaatagatt gcattgatga aaataccgat
    11821 tagtaggaca caagtaaaga acaaatagct ttttatctct ccatctagga gtctttgtaa
    11881 accactccca tcagaaaata gagaattcca ttcaagagga gaaaaagtcc caaagaaata
    11941 ggttataatt gcaattatca gcacagtcac taaatatatc aaacaaggga tacttgcaac
    12001 ttgcaaagtc aactttcttt ttaacccttg atagctcact tctcttccaa tactcaatcg
    12061 taaaacttta tttttcagct caatatattg aaaacctagc aaaacaatga tgattggaat
    12121 aataaatgat tgataaaaac ctagattgaa ctggagaata cgaaaatcta atgctgattt
    12181 taataagtca tttttaattg cttgtccatc gaatttagct agatcgggcg catgaatatc
    12241 aaaaaagaaa taagtcatca aaacatcacg ataaaccaaa gcaagaaaaa gcaaagtaag
    12301 caagacataa acaaatttat gccttgccaa agttaagaga ggaatcttca taagccacct
    12361 cctacaaata gaaagtaata taatactcaa tgaaaatcaa agagcaaact aggaaactag
    12421 ccgcaagttg ctcaaagcac tgctttgagg ttgtagataa gactgacgaa gtcagttaca
    12481 tatataatcc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt ataaatcaat
    12541 gccttccgcc tttagacttc cctagttccc gtctcaagtc aagcattttt ttgaaacaga
    12601 tatagtctaa ccagtcacta gcaaaagcga taagtagtaa taatagccaa ataccccata
    12661 acttgatatc tgtcaaattt ctcaagacga tattgaaaaa cagaactgaa aaaactgtcc
    12721 aagcaaggct aaaaagagca tagagggtga tgtaaatcca gtaaaaatag taaaaaattg
    12781 ggaaaatctt actatctctg tttgcctttt caatccagct gaaaaagtaa aaacagggca
    12841 ataagattat cattttaaac aagtattcca tcacaaacct cctcttttaa attgttttct
    12901 ttagtttcgt tctattaaat gttattacca atataaacct tggaatagcg tgtaataaat
    12961 gattttagag gtaccataag ccacctccta caaatagaaa ccgatataaa tcaatgcctt
    13021 ccacccttag acttccctag ttcctgtctc aagcgaaaca tttctttgaa acaggaataa
    13081 gttaaccaat tcataccaat agctagcaga ataaaaagaa accaaatgcc ccataacttg
    13141 atatctgtca catttctcaa gacggtattg aaaaacagaa ctgaaacaac tgtccaagca
    13201 aggctaaaaa gagaatagaa ggggatgtaa aaccagtaaa aataataaaa aattggaaaa
    13261 aacttactat ttctgttggc cttctcaatc cagttatcaa aataaaagta cggtgctaaa
    13321 agtaagaatt taaacaaatg ttccatcacc gacatcaccc tccttctttt gatagcgttt
    13381 tctattattt tattatatca aaaaaatccg gaactgtcat tccagattct acttttttat
    13441 ttgcgttttc ttgcgatgag atgaatcggt gttccctcaa aaacaaaggc cttgcggatt
    13501 tgattttcca agaaacgcag gtaagaaaag tgcatgagtt cttcttcatt gacaaagatg
    13561 acaaaggttg gtggtttggt tgccacttgg gtcgcataga aaatcttgag acgttttcct
    13621 ttgtctgtcg gtgttgggtt gatggcaatg gcatccatga tgacatcgtt caagacagct
    13681 gatggaatac gtgtattttg actttcgctg atttgcttaa tcatctcagg aagtttgtgg
    13741 agacgttgct tagtcaaagc tgatacaaaa ataatcggtg cataaggcag gtattggaac
    13801 tgctcacgga tatcttcttc ccagtttttc atggtatggt tgtctttttc aagcgtatcc
    13861 cacttgttga ctacgataat cattccttta ccagcttcat gggcaaatcc tgcgatacgc
    13921 ttgtcgtact cacgaatgcc ttcttccgca ttgatgacca tcaagaccac atctgaacgg
    13981 tcaatagcac gcatggcacg cataacagag tatttctcag tattttcata aaccttacca
    14041 gacttacgca taccagccgt atcaatcatg gtaaactctt gaccatctgt atctgtaaag
    14101 tgggtatcaa tagcgtcacg agttgttcca gcaacaggac tggcaatgac acggtcttct
    14161 cccaagatag cattaatcaa gcttgatttt ccaacgttag gacgaccaat caagctaaac
    14221 ttaatgacat ctggattttc ttcttcatat tcatttggaa ggttttccac aatcgcatct
    14281 agtacatccc ctgtaccgat accatggaca gatgagatag gcagtggttc acccaaaccg
    14341 agagcataga aatcatagat atcatttctc atctcagggt tatccacctt gttgactgcg
    14401 aggataactg gtttgtgggt cttataaagc ttgcgggcta cgtattcgtc tgcatcggta
    14461 attccttcct taccggacac gacaaagacg ataacatctg cttcttccat ggcaatttct
    14521 gcctggtgct tgatttgttc catgaaagga gcatcgacat catcaattcc tcctgtatca
    14581 atcatgctaa aagaacgatt gagccactca cccgttgcat aaatacggtc acgtgtcact
    14641 ccttcgacat cttctacaat ggagattcgc tcaccagcga tccgattaaa tagggttgat
    14701 ttcccaacat tgggacgtcc tacaatggca atagttggta gggccataat ttctcacttt
    14761 ctacaataat ttcttctgtt caagattttt tctagttgag cttggttcag cttgaccaaa
    14821 ctgttctgct aggcgctgac tccagcttgt ggtcgcacgc cccccagcat agtcagcctg
    14881 cacacggtca taagcttgga ttgtctcagt tgactgttct tggtattctt cctcaaagac
    14941 aacattctct agtggcagtc tcggtttcac atcatgatgt tgatttggca cacccagtgc
    15001 catcccaaag acagaatagg tgtagtcagg taggttaaag agctctgcca cttcttcaga
    15061 cttgtatcga accaaaccga taatcacacc accatagccc aagctttcag ctgccaacaa
    15121 ggcgttttgt ccagcaagag ctgcatcgac cgaactaatc aagagacctt ccacaccttg
    15181 gggttggaag gtgtcggtat gaagtcgggc tcccttttct gctcggttca aatctccgac
    15241 aaagagaagg aaaacagcag actggcgaat ggcttcttga ggtaccaatt catacaaggc
    15301 atctttcttc tcttgacttc gtaccacaat cacagagtag gattggaaat tcttccaaga
    15361 tgatgccatc tgggctgctg tcaaaatctc atttaagtct acttggggaa tttcttgctc
    15421 tttaaacctg cgcactgaag tatgagcctt catcaattta atggtttctg tcatcgacgg
    15481 tttactcctt ctaaacgagt ctcctcagcc aaataacgga tgcgttccat gacccgtctg
    15541 gcttcccagg tttcgtcatt tccatgtttc actttcgcaa aatgcttctc caaatcttca
    15601 aagttgaagt tggatgtgaa aaaggtcggt aaattttcct gcatccgata ttggagaatg
    15661 acctgcagga tttcgtcacg tacccaaacg gttgattgct cggcgccaat atcatctaaa
    15721 atcaggacct cagacagctt aatctcatcc accaaggtct taacattgcc atcactgata
    15781 gcatttttga catcaatgac aaagctagga tagtggagga gagttgatga aacaccacgt
    15841 ttttctgata aatcatgagc taaggccgcc accatgaaac ttttacccac accaaagtct
    15901 ccatataagt aaagaccttt tcgaatagct ggatattgct ccacgaaggc tagtagcttt
    15961 tcaaaaactg gtaagcgccc caaatcatcc aagtcaactt gagccaaact agctttcttg
    16021 agactggctg gtagattgat taacttgaga cggttcttaa tagccgcttc tttttcagcc
    16081 gcgattagct caggagtttc ttcatatgaa acatctgcat agccatgatt cttaaccaaa
    16141 atcggcttgt agcctttggc aatataatcc gtatccccac ggagaaactt gtcacgctcg
    16201 gtgatgtact gattaaactt ggagatactg cgatttaatt cctctggagt caaggattct
    16261 tgctggataa aagccgcaac atcagggtcc ttcatgattt tctggaccaa atcttgataa
    16321 taaaaacggc tgggttgacg tttgagtacg tctccgacac tttccatcta atctcctcct
    16381 ttttctaatc gagctaatag ttcttgcttc ttacgttcta gttccagacg agtttcctcg
    16441 ctggtttcat tcttatattc aggattactc catttaggaa cattggtttt tactggggca
    16501 gtctgattct gtttttgtgt ttttgctttc tgtcctcgct cacggatgcg caagactgcc
    16561 ttttctgccg aatgaatctt ttgataggca tagtcattgg ctaccttcat ggcatatttc
    16621 tcattgatat ttgccgaatc gaccttatta aaggtcaata aaagaatgat attgatgact
    16681 tcgtccagca agcccaagcc agccatctgt tgcaagagtt ctctttctgt ttgggtaatg
    16741 gttcccttgc gtgtttgctt gatttctgcc aagaactgca gggcagtttt acttttggct
    16801 tctttgataa tggttgtttc cttaagacta aagtcagagg aaactggttt ttgagcaatt
    16861 ttttcacgca tgcgtttggt tgaaataacc tgagaaacag ctgttgactt ggccaattga
    16921 taggtttcaa accaagtcca tttcttctcc tcggcaatag caaagaggtt taagacatcg
    16981 gactgctcat ccgcaaaacg aagtccatct cgagccatca gctggcgaaa atgttccaag
    17041 tcaaaatcat tggccacttt cttcttgaga ccaaggtctt cttgactgcc tagttctgcc
    17101 aattctggaa agacttgatt gagtgagaca ggtatttctt caccatcagc actttcaact
    17161 ttcaaatcct ccacagcaga gtcgccaatc tttttctcta agagtctgcg ataaacagga
    17221 tgctccaaga agtcttgact agatagagga gcatggaggg ctagctgata aacatccccc
    17281 ttttgataga gggtcaagag attaaaagca gataagattt tcaatgattt tatcagtcta
    17341 tccatcccaa agttgagatg attgaggata cttgaaaaaa gatattcctt tctaccatta
    17401 tcccaaaaac tgattgtata aagataaagg ctcagtgcct cctgaccgat aatcgggagg
    17461 tagcactgta ccagagatga ggtatcttgc gacacccgat tattctttag ataagaaaaa
    17521 cggtcaattg gcttcattta tctttccttt ttctttttag aggactgggt gatttgttgg
    17581 agcaagctct ctaactcact gacatcctta aaactacgat agacactagc aaaacgtaca
    17641 taggtaatct cgtccaattc agccaactcc tccatgacga gtgaaccaat gtcctcactt
    17701 tgaatttcat tttcatttcg accacggagt ttctgttcga tacgattgac taccatgttg
    17761 atttcatcac ttgacacagg acgtttctgg gctgagcgga taatcccatt aaagatttta
    17821 tctctggaga attgttcccg tgtaccatct tttttaacaa ccactaaggt tctttcttct
    17881 actcgttcgt aggttgtaaa acggtgttgg cattcgtcgc actcacgtct tctacgaatg
    17941 gtgttccctt cttctgcttg gcgactatcg ataacacttg acttggtagc cccacatttt
    18001 ggacaacgca tcctttccct ccttatcgtt ttcttttcat tataccattt tttaagcgat
    18061 tcccaaaaca attcttcttt ttgcttgaca agttttttgt tttgttgtat tatttaatta
    18121 agacaaaagg ataagagaaa ggagactaag atgtcctgga catttgacaa caaaaaaccc
    18181 atctatttac agattatgga gaaaatcaag cttcagattg tttcccatac actggaaccc
    18241 aatcaacaac ttccaaccgt gagggagcta gctagcgagg ctggtgtcaa tcccaatacc
    18301 atccaaagag ccttatcaga ccttgaacga gaaggatttg tctacagcaa gcgaacaact
    18361 ggacgatttg tgactaagga taaggagcta atcgcccagt cacgcaaaca attatcagaa
    18421 gaagaattgg aacacttcgt ttcctccatg acccattttg gctatgaaaa agaagaacta
    18481 ccaggcgtag tcagtgatta tattaaagga gtttaagcct atgtcattac tagtatttga
    18541 aaatgtatcc aaatcatatg gagcaacacc agcccttgaa aatgtttctc ttgacattcc
    18601 agctggaaaa attgtcggcc ttcttgggcc aaacggctca ggaaaaacaa ccctgattaa
    18661 actaattaat ggcctcttac aaccagatca aggacgtgtc ctcatcaacg acatggaccc
    18721 aagcccagca accaaggccg ttgtagctta tttgcctgat acgacctatc tcaatgagca
    18781 aatgaaggtc aaagaagccc taacctactt caagaccttc tataaagatt tcaatcttga
    18841 acgcgcccat catctacttg cagacctggg cattgatgaa aatagtcgtc tcaagaaact
    18901 atcaaaagga aacaaagaaa aggttcaact gattttggtt atgagccgtg atgctcgtct
    18961 ctatgttttg gacgaaccca ttggtggggt ggatccagca gcccgtgctt atatcctcaa
    19021 taccattatc aacaactact caccaacttc taccgttttg atttctaccc acttgatttc
    19081 tgatatcgag ccaatcttgg atgaaattgt cttcctaaaa gacggaaaag tcgtccgtca
    19141 aggaaatgta gatgatattc gctacgagtc aggtgaatcc attgaccaac tcttccgtca
    19201 ggaatttaag gcctaagcaa aggagattat ttatgttttg gaatttagtt cgctacgaat
    19261 ttaaaaatgt taacaagtgg tatttagccc tctacgcagc cgtgctagtc ctttctgccc
    19321 tcatcggaat acagacacaa ggctttaaaa atctacctta ccaagaaagt caggctacta
    19381 tgctactttt tctagctaca gtctttggtg gcttgatgct tacacttggg atttcaacca
    19441 ttttcttgat tattaaacgc ttcaaaggta gtgtctacga ccgacaaggc tatctgactt
    19501 tgaccttgcc agtttctgaa caccatatca tcacagccaa actaatcggt gcctttatct
    19561 ggtcattgat tagcaccgct gtattggctc taagtgctgt tattattctg gctttaacag
    19621 ctccagaatg gattcctctt tcttatgtga ttacatttgt agaaacacat cttcctcaga
    19681 tctttcttac aggtatatcc ttcctactaa atactatttc aggaatcctc tgcatctacc
    19741 tggctatttc cattggacag cttttcaatg aataccgtac agcactcgct gttgcagtct
    19801 acattggtat ccaaatcgtc attggattta ttgaactttt cttcaatctt agttctaatt
    19861 tctatgtcaa ttcactggta ggactcaatg accatttcta tatgggagca ggtatagcca
    19921 ttgttgaaga actcatattc atagctatct tttatctcgg aacctactac atcttgagaa
    19981 ataaggttaa tttgctttaa ataattttta cctagatatg taacatactc atagaacaaa
    20041 agagaccagg caaaaagtct ttacaattag aaaacgcata gtatcaagtg ttaaaaatcc
    20101 ttgatattat gcgttttttg tgagctgact tatttccttt cactatatcg caaaatgaaa
    20161 taagaacgga acgatgggat tttggaattc aaatcaattt ataagaatgt tttagaagta
    20221 atattatcct attccagatt cagttcacta tacaattgag ttttcaagca acctgtttac
    20281 ataatgtgta cataattagg ttcgtgattc cacccttttc acctttaaaa acctcgcttt
    20341 cgcaaggctc ttctatttat aagataaggc acgtttaaag gttttccaaa tccctaaatc
    20401 atccgtttga agaacgagac tagcatacat gcgtccgata aatcctgttg ctaccaccgc
    20461 aaaaatcact gtaatagcaa gtgaaatcca tgcttccgct ccctccgcat agccattaat
    20521 cgttcgaaac ggcataaaga aggtcgaaat aaagggaata taagaaccaa tcttcaagag
    20581 gagattgtca ccagctgcac ctagagctgt cactccaaaa aaaccaccca taatcaaaat
    20641 catcaaaggc gacaaggctt tccctgagtc ttcaggacga gaaaccatag atcctaggaa
    20701 ggctgccaag actacgtaca tgaaaagact gatcaaaata aagagcaagg tattcagtga
    20761 gatagcatct cccaagtgat ccaaaatacc agactgagcc aagaatggca aatctttaaa
    20821 gagcaaaacg gcagccagac cacctacaac atagatccca atatgcgtta aaatcactag
    20881 aaacagagcc atcatccgcg catagaaata gtgacttgcc cttatgctag aaaagacgac
    20941 ttccataatt ttggtgcctt tttcactggc aacttcctga gctgttacac ccgcataggt
    21001 aatcagaatc atataaagaa agaatcctaa ggcacctgct gcaattgttt gaataaactt
    21061 tttattttcc ttggcttcat caatcttttc tgtgaattga attgtctgcg ctaagcgttt
    21121 ttcctgctct tgagacaagg aagcagttga acgattaagc tgattttgca gttcattgag
    21181 tgtacctgta acctcaaatt taattccatt ttcaagcgat gtttcgccat gataaactgc
    21241 ctttagaaca ctatcttctt gatcaatggt caaataacct tttaattttt cttctttaat
    21301 tgcttctttg gcacttgctt cgtctttata gtcgaagtta acaccattta cattcttcag
    21361 tccttctgct acagatggca ctgttgtcac tactgccact ttattatttt tagccataga
    21421 agaaccttgg agatgcccaa ttcctacaga gattcctaaa aagaggaacg gcgaaatcac
    21481 cataaagaag aaactccatg actcgacatg tcgaagatag gtttccttga ttacaaccca
    21541 catatttctc atacttccac tcctgattct agtttaaaga tttcatcgat agttggcgct
    21601 tgttggtcaa atgttgcgat atattgacct tgagtcaaga ttgggaagag ttcccttcca
    21661 gcgctctcat cctccaaaat caatttccaa ctgccttgtt tggtcaagct cacctgtttg
    21721 acatgaggaa gattttccaa ttcttccttg cttcgttcac ttgaaacaaa gagacgcgtt
    21781 ttcccgtatt gattgcggac atcctgaact ggtccgtgca agaccacacg gccatctcga
    21841 atcatcagaa tatcgtcaca aagttcctca acattggtca tgacatggtc agaaaagata
    21901 atggttgctc cgcgctcttt ttcctgaaaa atgacttgtt tgagcaattc tgtattaact
    21961 gggtccaatc cactaaaagg ctcatccaag ataatcaggt ctggttcatg aatcagagta
    22021 ataatgagct gaatcttctg ctgatttcct tttgacagac tcttgatttt atctgtcagc
    22081 tttcctttta cttccaacct cttcatccat tgagggagtt tttctttgac ttctttggca
    22141 tccatgcctt ttagagtcgc caagtagcga acttgttcaa gaactgtcaa tttaggcatg
    22201 agactgcgtt cttcaggcag ataaccaatc cgagcataga tctcctgacg aatatcctga
    22261 ccatccagac cgatttctcc ctgatattct aggaatttta aaatactatg gaaaatcgtt
    22321 gtttttccag caccattttt tccgactagt cccaaaatac gacctggtcg cgcttgaaag
    22381 tcaataccaa acaaaacttg cttggatcca aaacttttct ctagacttct tacttctagc
    22441 atctttcacc tccgaaattt cttgcactca ttatactcct ttttgatagc ctttacaatg
    22501 ttttttgtcc atttttagaa gactattgct gtgtaaaata tggcctggag cacttttata
    22561 ctcaatgaaa atcaaagagc aaactaggaa gccagccgta gactgctcaa agtacagctt
    22621 tgaggttgca gata
//
LOCUS       DAVBNZ010000032        22342 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000032 DAVBNZ010000000
VERSION     DAVBNZ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22342
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.032"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(300..587)
                     /locus_tag="VQ860_001300"
     CDS             complement(300..587)
                     /locus_tag="VQ860_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119726.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(597..1007)
                     /locus_tag="VQ860_001301"
     CDS             complement(597..1007)
                     /locus_tag="VQ860_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3119727.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            1075..1806
                     /locus_tag="VQ860_001302"
     CDS             1075..1806
                     /locus_tag="VQ860_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119728.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            1803..2852
                     /locus_tag="VQ860_001303"
     CDS             1803..2852
                     /locus_tag="VQ860_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3119729.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPMDKGQKEKGLQEVVRGLTSFVLLVEVVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(3020..3349)
                     /locus_tag="VQ860_001304"
     CDS             complement(3020..3349)
                     /locus_tag="VQ860_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET3119730.1"
                     /translation="MTDTDPIKRAQTLITDLNKAYQACKQATADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            3626..3964
                     /locus_tag="VQ860_001305"
     CDS             3626..3964
                     /locus_tag="VQ860_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3119731.1"
                     /translation="MKHMIIQTQKTVYKVNVDDVYYIQTHPTKAHTVKIVTEEASFNM
                     VQNLSNLENQYGETLMRCHRNCLVNLDKVKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            3969..4706
                     /locus_tag="VQ860_001306"
     CDS             3969..4706
                     /locus_tag="VQ860_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3119732.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            4720..6060
                     /locus_tag="VQ860_001307"
     CDS             4720..6060
                     /locus_tag="VQ860_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3119733.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGVSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6104..6259)
                     /gene="blpC"
                     /locus_tag="VQ860_001308"
     CDS             complement(6104..6259)
                     /gene="blpC"
                     /locus_tag="VQ860_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET3119734.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FYQPIQL"
     gene            complement(6316..7677)
                     /locus_tag="VQ860_001309"
     CDS             complement(6316..7677)
                     /locus_tag="VQ860_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET3119735.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASIKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            complement(7688..9841)
                     /gene="blpA"
                     /locus_tag="VQ860_001310"
     CDS             complement(7688..9841)
                     /gene="blpA"
                     /locus_tag="VQ860_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HET3119736.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLNQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            10123..10377
                     /gene="blpM"
                     /locus_tag="VQ860_001311"
     CDS             10123..10377
                     /gene="blpM"
                     /locus_tag="VQ860_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET3119737.1"
                     /translation="MNTKMMEQFHEMDIAMLSSIEGGKNNWQTNVFEGGSAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            10393..10596
                     /gene="blpN"
                     /locus_tag="VQ860_001312"
     CDS             10393..10596
                     /gene="blpN"
                     /locus_tag="VQ860_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET3119738.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            10840..10989
                     /gene="blpO"
                     /locus_tag="VQ860_001313"
     CDS             10840..10989
                     /gene="blpO"
                     /locus_tag="VQ860_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET3119739.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            11093..11212
                     /locus_tag="VQ860_001314"
     CDS             11093..11212
                     /locus_tag="VQ860_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET3119740.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            11680..12051
                     /locus_tag="VQ860_001315"
     CDS             11680..12051
                     /locus_tag="VQ860_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119741.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLTIMLLLIWGLKYYKK"
     gene            12680..13063
                     /locus_tag="VQ860_001316"
     CDS             12680..13063
                     /locus_tag="VQ860_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET3119742.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            13115..13804
                     /locus_tag="VQ860_001317"
     CDS             13115..13804
                     /locus_tag="VQ860_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3119743.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            13846..14079
                     /locus_tag="VQ860_001318"
     CDS             13846..14079
                     /locus_tag="VQ860_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119744.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            14230..14841
                     /locus_tag="VQ860_001319"
     CDS             14230..14841
                     /locus_tag="VQ860_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3119745.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGVFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            15002..15796
                     /locus_tag="VQ860_001320"
     CDS             15002..15796
                     /locus_tag="VQ860_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET3119746.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            15793..16428
                     /gene="trmB"
                     /locus_tag="VQ860_001321"
     CDS             15793..16428
                     /gene="trmB"
                     /locus_tag="VQ860_001321"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET3119747.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            16554..17033
                     /gene="rimP"
                     /locus_tag="VQ860_001322"
     CDS             16554..17033
                     /gene="rimP"
                     /locus_tag="VQ860_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET3119748.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            17077..18213
                     /gene="nusA"
                     /locus_tag="VQ860_001323"
     CDS             17077..18213
                     /gene="nusA"
                     /locus_tag="VQ860_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET3119749.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            18235..18528
                     /locus_tag="VQ860_001324"
     CDS             18235..18528
                     /locus_tag="VQ860_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET3119750.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            18521..18820
                     /locus_tag="VQ860_001325"
     CDS             18521..18820
                     /locus_tag="VQ860_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET3119751.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            18837..21629
                     /gene="infB"
                     /locus_tag="VQ860_001326"
     CDS             18837..21629
                     /gene="infB"
                     /locus_tag="VQ860_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET3119752.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDCYNDI
                     KMDDVIEAYVMEEIKR"
     gene            21880..22230
                     /gene="rbfA"
                     /locus_tag="VQ860_001327"
     CDS             21880..22230
                     /gene="rbfA"
                     /locus_tag="VQ860_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET3119753.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         6601 a         3882 c         4889 g         6970 t
ORIGIN      
        1 aacctcaaaa cagtgttttg agctgacttc gtcagttcta tccacaacct taaaacggtg
       61 ttttgagcag tctgtgccta gctttctagt ttgctttttg atttttattg agtatgagtt
      121 acctaaatta tgatgcatag ttgatgggat atatataata gattgaaata gaatatgaac
      181 aaattgataa gaggatttta aagtaatctc taacaatgct ttagaaacta tagtgtgcta
      241 ttctaaattc aattcactat aacttgttta cgttttaaaa aagagccggg gggctctttt
      301 tacttatctt cagttccctg catttctttt atcacagcta gtctagtctg gatatccttt
      361 tccaagacct taaacttgta agtcaagtct tcttggtatt ccttgataag ttctttttgc
      421 tggttaatga tttgcaggct gttttggata atatccacat cgtccttgat agcttgaacg
      481 cggtcagtgg tattcaagac ttcatctgtg atggtttggc gattttttgt aaccagataa
      541 cttccggctg cagctcctgc aaatagcagt aggttggata atttcatagc aactccttaa
      601 gcgtttttga tggtttcagc gacttgagca agtttgtcaa agtctggttc gtgggcgata
      661 aaatcaatct tgaggtcatc gtcagcactg tagcgaggca caaggtgaac gtgagtatga
      721 aaaactgttt gaccagcgac ttcttcacag ttggaaatga tattcatacc agcagcctta
      781 gtgactttca tgactttttg agctactttt ggtacttggg caaagagttg gctggcgctc
      841 gtagcatcca tctccaaaag attgcgatag tgttcttttg gcacgaccaa ggtgtgtcct
      901 agtgttactt gagagatatc aagaaaggca aggacctgct catcttcata tacttttgaa
      961 gcaggaattt cccctgcgat gattttacaa aaaatgcaat ctgacataaa atctacctct
     1021 actgtactga attttgatat aatatagcta cattatacca gatttggaga aaatatgtta
     1081 gaaattaaaa acctgacagg tggctatgtt catgttcctg ttttgaaaga tgtgtccttt
     1141 actgttgaaa gtgggcagtt ggtcggtttg attggtctca atggtgctgg gaaatcaacg
     1201 acgatcaatg agattatcgg tctgttggca ccttatagtg gctccatcaa tatcaatggc
     1261 ctgactctgc aaggagatgc gactagctac cgcaagcaga ttggctacat tcctgagacg
     1321 cctagtctgt atgaggaatt gaccctcaga gagcatatcg aaacggttgc tatggcttac
     1381 ggtattgagc aaaaagtggc tttcgaacga gtagagccct tgttaaaaat gttccgtttg
     1441 gaacagaaat tagactggtt ccctgttcat ttttcaaaag ggatgaagca gaaggtcatg
     1501 attatctgtg cttttgtggt ggatccaagt cttttcatcg tggatgagcc tttccttggt
     1561 cttgatccgc tggctatttc tgatttgatt cagcttttgg aagtggagaa gcaaaagggc
     1621 aagtctattc tcatgagtac ccacgtgctg gattcggcgg agaagatgtg tgatgccttt
     1681 gtcattcttc acaagggaga ggtgcgtgcc aaaggcaatc tcctgcaact acgtgaagcc
     1741 tttgatatgc ctgaggctag tttgaatgat atttacttgg ctctgaccaa agaggaggat
     1801 ctatgaaaga cttgttttta aagagaaagc aggcctttcg taaggagtgt cttggttatc
     1861 tgcgctatgt gctcaatgac cactttgtct tgttcctgct tgtcctgttg ggctttctag
     1921 cctaccagta cagtcaactc ttacaacatt ttcctgaaaa tcattggcct atccttttgt
     1981 ttgtaggaat tacgtctgtt ttacttttac tttggggagg aattgccacc tatatggagg
     2041 ctccagacaa gctctttctc ttagttggag aagaggaaat caagctccat ctcaagcgtc
     2101 aaactggcat ttccctagtc ttttggctct ttgtacagac ccttttcttg ctgttatttg
     2161 cgcccttgtt tttagcaatg ggttatggct tgccagtttt tctgctctat gtgcttttat
     2221 tgggggtagg aaaatatttc cactttcgtc aaaaggccag caaatttttc actgaaactg
     2281 gactggactg ggactatctt atttctcaag aaagcaagcg taagcaagtc ttgcttcgtt
     2341 tctttgccct ctttacgcag gtcaagggaa tttcaaacag tgtcaagcgt cgtgcctatc
     2401 tggactttat cttaaaggct gttcagaagg tgcctgggaa gatttggcaa aatctctatc
     2461 tgcgttctta tctgcgaaat ggcgacctct ttgctctcag tcttcgtctt ctcttacttt
     2521 ccgtactggc gcaggttttt atcgagcaag cttggattgc gacagcagtg gtagttctct
     2581 ttaactacct cttgctcttc cagttgctgg ccctctatca tgcctttgac taccagtatt
     2641 tgacccaact ctttccgatg gacaaggggc aaaaggaaaa aggcttacag gaggtagttc
     2701 gaggattgac cagttttgtt ttacttgtgg aagtagttgt tgggttgatt accttccaag
     2761 aaaaactagc ccttctagcc ttactaggag ctggtttggt tttactagtc ttgtatttgc
     2821 cttatcaggt aaaacgtcag atgcaggact aacattgctg atacgacact aaaaaagaag
     2881 ttgagttcag tctgtctcaa cttctttttt gttactacag gataatggtt ggtccgtaga
     2941 gacttatact cttcgaaaat ctcttcaaac cacgtcagcg tcgtcttacc gtactcaagt
     3001 acagcttgcg gctagcttcc tagtttgctc tttgattctc attgagtatt aacttggtct
     3061 tgacttggtc aaagtggaag cggtcatagg cccgccaagc ggcgcgagtt ggagcatctg
     3121 gatcaagagc gctgagtccc atgagaagac tggaagtctg gtaaaatttt tccaattcaa
     3181 tcaagaatcg attatccact gtttcagcct tggctagaaa accaagaata gagtttaatt
     3241 gctcctgaaa gcggacgtcg tcagcggttg cctgtttgca tgcttgatag gctttgttta
     3301 agtcagtaat caaagtctga gctcttttga tagggtctgt atctgtcatg agaattcctc
     3361 ctctaatctg ggtgccagtc ttgattctag caactgtgtt ttgatactgt cagtctatca
     3421 cttttatctc ctttttcgcc tttaaatctt taattgtcat tgaaatgtct tgaattgcgc
     3481 tgagtgaatt ttatgataaa atagtggtaa gctcatcatg atattgtaga aaaataattc
     3541 ttttaggagc tttcaaagac tgtttaggat tgggtgtgct tgtgttagat tttttctgtt
     3601 attcttttct taggaggaga atccaatgaa acatatgatt attcagacac agaaaacagt
     3661 ctataaagta aacgtcgacg atgtctacta tatccaaaca catccaacta aagcccatac
     3721 tgtaaagatt gttacagaag aggctagttt taatatggtt caaaatttaa gtaatcttga
     3781 gaaccaatat ggggaaacct tgatgagatg tcatcgaaat tgtttggtca atcttgataa
     3841 agtaaaatcg attgattttc aagaaagaat cctttttctt ggagaagaag gtcaatacgc
     3901 tgtcaagtat gccagacgtc gctatagaga aattcgtcaa aaatggttga aagaaggaga
     3961 gtaagaagat gagaatattt gttttagaag atgatttttc ccaacagact agaattgaaa
     4021 cgacgattga gaaactcttg aaggaacatc atatcactct gagttctttt gaagtttttg
     4081 gtaagccaga tcaattgctg gcagaggtgc atgagaaggg ggcccatcag ctattctttt
     4141 tggatattga gattcgaaat gaggagatga agggtctgga agtggctaga aagattcggg
     4201 atcgggatcc gtatgccctg attgtctttg tgacgactca ctcggagttt atgcccctgt
     4261 cctttcgcta ccaagtgtct gctctggatt atattgataa ggccctttcg gcagaggagt
     4321 ttgaatctcg tatcgagaca gccctcctct atgccaatgg tcaagacagt aaaagtctag
     4381 cggaagattg cttttacttt aaatcaaaat ttgctcaatt ccagtatcct tttaaagagg
     4441 tttactatct cgaaacgtcc acaagacccc atcgtgttat tctctatacc aagacagaca
     4501 ggctggaatt tacagcgagt ctagaggagg ttctcaagca ggagcctcgt ctcttgcagt
     4561 gccatcgctc ttttctcatc aatcctgcca atgtggtgca tttagataag aaagaaaaac
     4621 tgcttttctt tcccaatggt ggaagttgtc taatcgcgcg ttataaggtc agggaagtgt
     4681 ctgaggctat taataactta cactgagcta ggagagttta tgaatgttgc ttggatattg
     4741 ttgtatacac ttgttactca cggattaaaa attgtcatat tctttaaggt agatggaatt
     4801 agtctcactt ttgagaggat ttttaaggcc tttcttttta agatactgtt ggccgttgtt
     4861 tttggaatgc ttggctatat ggtaggaaat gtttacctat cttattttat ggaacccttg
     4921 tacggcatag gcttatcttt cttattgtta agagaacttc ctaaaaaact ccttctcttt
     4981 tatggtctct ttccaatgat attagtgaat ctcttttata gaggtgtttc ctattttgtg
     5041 cttccatttt tgggacaagg gcaagtatat gatgactact catttatttg gttatgtata
     5101 ataattttca atttcttcat ttctctagct tttttgaaat ggttggacta tgatttcact
     5161 agcttgagaa aggggattct cgataaagat tttcaaaagt ccctgactca gattaactgg
     5221 ataatggggg cttactattt ggtgatacaa aatctgtctt actttgaata tgaacagggg
     5281 attcaatcaa cgactgttcg ccatctcatc ctagtctttt acctgctctt ttttatgggg
     5341 attatcaaga aattggatac ctatttgaag gacaaactcc atgagagact gaaccaagag
     5401 caggacttgc gctacagaga gatggagcgg tatagtcggc atatagagga gctttataag
     5461 gaagtacgga gttttcgcca tgactacacc aacctcttga ctagcttacg tctgggcatt
     5521 gaagaggagg atatggagca gataaaagag atctacgact cggtcttaaa ggattctagt
     5581 gaaaaattgc aggacaataa atatgacctt ggccgattgg tgaatgttcg ggatcgtgcc
     5641 ctcaaaagtc tcctagctgg aaaatttata aaagctagag ataagaacat tgtctttaat
     5701 gtcgaagttc cagaggagat tcaggtagag ggggtgagtc tacttgattt tctaaccgtt
     5761 gtgtctatcc tttgtgacaa cgctattgaa gctagtgtag aagcctgtca acctcatgtt
     5821 tcaattgcct tttttaaaaa tggagcacag gagaccttta tcattgaaaa ttccatcaaa
     5881 gaagagggaa tcgatatttc tgaaatcttc tcctttggag caagttctaa aggggaggag
     5941 agaggagttg gtctctatac cgttatgaaa attgtggaaa gtcatcccaa taccagtctc
     6001 aataccacct gccaagatca cgtttttcgt caggtactta ctgtaataca tatagaatga
     6061 agaaaaaata agaccgagag tgcgttctct tggtcttgtt tttttatagt tgtattggct
     6121 gataaaatcc ttttgtattt ttttgttcaa ttatattaaa tctatataag aaatcttccc
     6181 accatcctcc acctataatt tggttgagtt cggtagttgt tagttcttga aatgaagtta
     6241 ggttttgttt cttatccatg ttatgattct cctttttgat aagataataa atagttatag
     6301 agtgttatct gaaaattaat cagaatgggt taaaatttta tctttgaaat aatcaaaata
     6361 tgttttcttt gtagttacac tagtgacgcg accttgtaag ccatattgga tgagtttact
     6421 atcctcgtta gatagttttg caagagcggt taatttaaag agattgcctt gctctgttct
     6481 ggtaggagtt tgatcaatac tctgaagttg gccgatgatg gtggtgccgt gatttccaat
     6541 cttctccagt tttaatctta cagtttgtcc tttatctagt aaggggagat agtcagatga
     6601 tacgtagtaa gtgattagta cttctcttgt atctgtgatg acagggaata tttgagcaat
     6661 ttctgtacca gttggaattc tatttttacc ttcaaattcg ctgttcagat gaacgatacc
     6721 tttacttgga gcggttaagg tattattttc taagcgctgt gtcgcttgat ctagttgtac
     6781 ttttaattct gttaattgat tctccacggt tagttgttgc tgtgaggctg tttgtaaaaa
     6841 ctgagtgcgg agtacttcaa ttttggttgc taaactatta tcataagttg ctacacttcc
     6901 gataccagct tgctgaattt tgatgcttgc gatagatgat tcaagacttg caatactttg
     6961 attaatttga gataaaaatg gctcctctgc cgttccttgt gtttgtcctt gagaggctat
     7021 aagataacga tttaaaattg actggtgcgg attgccagtt ggtaagcgtg ctctgttatt
     7081 tatgatagca tctctcaact cttgatattc tccaatttgt tgttgaactt ttgtaatttc
     7141 ttgttcgatg gctgatgaac tgctattggt aagattagct tgatttgaaa cttcagtgtt
     7201 agtctttgag atacccagtt caatatcatg ggattgttta gtaaaattca taaaggtatt
     7261 atggtagcca aactcatcct cgctagaaaa aagatcagtc gctttttcta agctttgttt
     7321 caagattcca agtccttctt tttgcttctc aagtctttgt aattgagttg ctaaggcagt
     7381 tttctgactt tcttccattg tttcagagta tttgatgagt aagtcacctt tctcaactac
     7441 ttgatttgcc actaaatgat tagcaaggat aggattatca ctggtcgact gaatagatgc
     7501 aatgacactt gtaggggcga tttctccttg ggaagtaaca gtaatttctt ttgtggcaac
     7561 aagggagaaa atcaagatga aagtaaatag taatgaaaga ggtataatga acactgtcgc
     7621 atagttatgg taacgtctct gataaaactc gacacttcta aaaagattag gattcatgac
     7681 attctcctta tttattgaat agatgatggt agaagccttg cgcctgcatt aactcttggt
     7741 gactaccaac ttcaatgatt ttcccctggt taagaacaat gacacggtta gttcgttcgg
     7801 ctatactgag acgatgggct acaaagagaa tggttttatc agttagggat ataagattat
     7861 ctataacctt tttctcagtc aagacatcaa gaccgctagt agcttcatct agtattaaaa
     7921 caggagcttt agttaaaaga gcacgagcga gagcgattcg ttgcttttgt cctcctgata
     7981 gaccagctcc atcagagagc tgagtttgat agcccatagg cattctttca atgtcttgac
     8041 ggatttcagc taattcacaa gctcttagaa tatcttcttg gctaatcata tgattaccgc
     8101 ccaaggttaa attttccaag atagagccat taaagatata ggcttgttgg ggtaggtaat
     8161 taatatgacg gcgcaagact tttttatcaa tgtttttaat atcctgataa ttgatggaaa
     8221 tatgcccttt gtagggttca aagaaattga caatcatttt ggctaaagtt gttttaccag
     8281 aaccactaac tccaactagg ctaaccttat ctccttgttt aatcgtgaga ttaatatctg
     8341 ttaaggtatc tcgtccaaaa ccatacttat aagaaaggtc atcaaattca atatcgccca
     8401 tcaaaaaatg tgaatgaaca gggttttctt gaacttgaaa ttcagattcg actagataga
     8461 cttcgttcaa acggttatta gcgaccttcg cagattggag tttggtttgg aggttgataa
     8521 tattttccat aggagttgta aagtaagaaa aaagtgtgtt aaaggtaatc agctgaccga
     8581 tagaaatttt actcgacatg actaattgag cgccaaacca taggataagg atattcagaa
     8641 ctaattttgt tccctgcttt aaactcgttt gtaaaataga atatttactg agcttaaagg
     8701 atttttccaa ataatctaca aattcgctgt ctatattttg atagcgattt tcttcactcg
     8761 tgagcgactt tatagtttca atcccgttga tatcttcgat aatggcagag ctaaccatag
     8821 aattactttg catgacatca tggttcattt tttcgaaagg tttcataaaa gaaaagatga
     8881 tgaacatgta tataggaatg gaaagaagag aaaggaggaa gagattaggg ttttgtgcca
     8941 gtaagacgcc ccctacaaga atcagaatag aaacatccag aaaaagagaa agaatggtag
     9001 aagccaaggc atctataata gagttagcat ctgtgaaccg tgaaatgatt tctcctgtac
     9061 gacgtgtcgc aaagaaagac atgggaagtt caaaaatatg gcgaatatag gataaaatca
     9121 catcaatgct taatctctgg ctcagaacgg ttaggagata atctctggaa aagctcatga
     9181 cttgttggag gatataggtg ataaccagac caactgagat gattcctaaa gttgatttca
     9241 tctgatttgg gatgtattca tccaagattc cttggagata ataagaacca ccgatattga
     9301 taatagtgac caataagctt gagagaacaa tgtaagcaat gagagatttt tgtttgaaaa
     9361 tcagaggaag gaagcttagt agaccattct ttttatcttt atggggttga tagctgggtt
     9421 tgggagctag aaaaatagct actccagtcc attcagagaa aaagcgttct tttgacattt
     9481 tagtgatttt tacagaaggg tcaggatcac caataatcag atagtctttc tttgtttgat
     9541 agacaacata gtaatgttgg agttttcctt ctttgttaac gtgaacgata aatggatagg
     9601 ggacatcact catgtcaaag agagttttat ctgcttgaac aggccttgtt tcaaagccca
     9661 tttcatcagc ggcttttaca atgccaagag cagtcgtccc ttctttattg gtctttgcaa
     9721 gttctctcaa gtgagctaga gaaaaatctg aaccatagaa tttagcaatc gaggctaagg
     9781 cagcaacacc gcagtctcta gcatctattt gaggaacaaa tgtacgttta taagaagtca
     9841 ttggcaattc ctttcatata gtggatagct ctattatgac ataaaaacaa tttcgtgctt
     9901 tataaaatct tgaatagtca ttgaaatttc ctgaatggta aaaaagtgat tagaaattat
     9961 cttttaaaaa aaatttagag gtagttttaa ataaaaaagc taatttaaga cgtttcgatg
    10021 acaattcaag atttggatga aaaactttaa caaatagtgc tatactaaac ttgtcaaagt
    10081 tgcaacaaga caaaaattaa aaataaaaaa ggagtatttg ttatgaatac aaaaatgatg
    10141 gaacaatttc atgaaatgga tatagctatg ttatctagta ttgaaggagg caagaataat
    10201 tggcaaacta atgttttcga aggtggtagt gctgcttttg gtggctgggg gttagggaca
    10261 gctatttgtg ctgcgagtgg tgttggagcg ccatttatgg gagcatgtgg atacatagga
    10321 gctaaatttg gtgtggctct ttgggcagga gtaacagggg caacgggtgg attttaacaa
    10381 aaggagactt gtatgaatac ttattgtaat ataaatgaaa caatgctgag tgaggtttac
    10441 ggaggtaatt ccggaggagc agctgtagtt gctgctttag gttgtgcagc gggtggagtg
    10501 aaatatggga aaattctagg accatggggc gctgcaatag gaggaattgg aggagcagtg
    10561 gtttgtggat atttagccta taccgctaca tcataaaaat gaaagctaaa ttttatgaag
    10621 gctatattct ttattattct cttcgctttt caaacctatc ttatttatct atccataagt
    10681 atctctgata aaaaacaaaa gactattgaa ttaacatcat tgaattgttt tgtcatatta
    10741 tttctaatct atgataaatt aatttttctc tttattgcct atgttttttt gataattttt
    10801 atattaaact tgttccgtaa ctgaaaagtg acatactata tgaatacaaa aatgatgtca
    10861 caattttctg ttatggataa tgaaatgctt gcttgcgttg aaggtggaga tattgattgg
    10921 ggaagaaaaa ttagttgtgc agcaggggtt gcatatggcg caattgatgg gtgtgcaaca
    10981 acggtttgac atttctattg ggaccatttg ctataggaat aggtgtaact ggtgctgcag
    11041 gtggagctat acttggaggt gtagcctatg cagcaacatg ttggtggtaa ttatggattt
    11101 taaaagtttt attattggtt tagtagttgg tatatttggt ccttatatgg atgacttaat
    11161 tagaaaaata ttttcaaaat cttccaaaaa ggatacggat agtactctct aaaaaataaa
    11221 tttctcccct gtatttgcta gcttaattta caggcgagtt tctttaatat tgtttcgcct
    11281 gtcaaaatga tatgtgatag caggatgaaa agtctacaaa caagttggta tcaatacaat
    11341 ataaagagga aagtatgttt ttcatgcttg cttttttaat ttttacaatt caagaggttt
    11401 tgatgaccat ttatgatttg agtgatccaa ggtcaaaata agtgctatac tagcagtgta
    11461 aatgttcttg ctcaactaag ataaatcgca catttaggag gaaatcttat gaagaaaaaa
    11521 atactgatta ttttcgttct gtatctgatc atgtccatct ttctttatcc gcttagggag
    11581 agtatttggt ataatctatt ttataccata gcctatatga ttgcggttat gatctatttt
    11641 tctttaatta aaaagaaaga aaagaaatga aagattttct tgattaaaaa gaatcatatt
    11701 ctttgtgaga ttgttcctgg gtcagttgcc tttgcttgtt tctacttatc tatttctatt
    11761 tcgtcagttt tccaatttct tttagtggtt attaacttag cttctatttt ggtcactgtt
    11821 tacctcacta gggaaatgcg gataaaagag tttgaagatg atgatttggt tagtcctaga
    11881 accaatcaac ttatgttcat cggcttgaca ggctttatgt ctattatttg tttgtataga
    11941 gggatcacag caggagaatc ctaccaacaa ataatcgctt atattggcgc tattctctgc
    12001 ttgaccatca tgcttctgct catttgggga ttgaagtatt ataaaaagta gaggctaatg
    12061 cagtttttgc aatttaagat gtcttgatga caattcaaga tttggatgaa aaactttgac
    12121 aaatagtgct atactgaaat tgtcaaagtt gcaacgggtg ctgctacatt atgttaaaaa
    12181 tcgctcttga ttgataagtt ggatttgtta ggaaaggagt aaataattat ggataagaaa
    12241 aagatagttt cgactataat atgtatagta tttcttgtag tgtcagtaga taattttttt
    12301 agagacttaa ccccgttact gttcatttta aatattattg gcctgtcttg cttttcagtg
    12361 ctaacataca ttaacataaa agagatactc ttaaatataa gtaaatgatg atttggttag
    12421 tcctagaacc aatcaactta tgtttatcgg cttggcagat tttatgtttg tcatttgttt
    12481 gtatagaggt atttcagaaa cagaattcta tcaacaacta atcgcttata taggtgtatt
    12541 ctctgcttgt ttatcacgct tctgctcatg tggggcttga agtattataa aaagtagctt
    12601 tctatccttt tctgacagga tatttgagta gaaggctcta ttaaattgtt agtgaaataa
    12661 atgaatggag gtatttaata tgaaatacag attatttttt gttattttct tgagtagtgt
    12721 gttggatatt cttttaggga catttttaca aatctctatc gtatctattg ggtggcttgt
    12781 tctttacagt ggtttgtttg aagcaggagt tttccttctt gctaataaag gggtggcggt
    12841 aaaaatcaag gaagtagata ttcgaaatcg ctttaaattt atttttggaa aaaccttatg
    12901 gtttcaaatt cttttgctca tctttttgat aatcaaactt tatcttggtt tggatgcgag
    12961 gttgatttta ttctatggac atattttcat tgtctttaat gccttaatgt atctattatc
    13021 tagtagtcag gttagcctta aaaaaaacaa actgtcttct taatcttaca gcagtagagc
    13081 ctgacaaggt gaggtcatag tagggaggat ttctatgaaa aagtatcaac ttctattcaa
    13141 aataagtgca gttttctctt acttattttt cgtatttggt ctttctcaga tgacgcttat
    13201 tattcaaaat tattggcaat tttcttccca gattggcaat ttcgtctgga ttcaaaattt
    13261 cttgagtttg ctatttagcg gagtcatgat ttggattctg gttaagacag gtcatggtta
    13321 tctctttcac attccaagaa aaaaatggct ttggtattcg attttgacag tattagtggt
    13381 agtgctccag atctctttta acgttcagac agctaaacat gttcagtcaa ctgctgaagg
    13441 ttgggctgta ttgatcggtt atagtgggac caactttgct gagctaggta tctatataac
    13501 tttgttcttt ctgactccac ttatggaaga gctaatctat agaggattac tgcaacacgc
    13561 cttttttaag cattcgagat ttggccttga tttgcttctt ccgtcaattt tatttgctct
    13621 tcctcatttt tcaagcctgc ctagtttgtt agatatcttc atctttgcaa catctggcat
    13681 catctttgct agtttgaccc gctataccaa gagcatttat ccttcctatg cggtgcatgt
    13741 gatcaataat attttcgcaa cattaccatt tttgctgact tttttacata gggtcttggg
    13801 gtaaaaaaac aaaaggcttg cttttcagcc atagaggaga ttatcatgta taaacactta
    13861 tttttcctag attccaaaac tttagatcgg ttgacaccct atattctagt cttggcttct
    13921 gacaccattg cttttaatgt ttttgtgcta acctttgtat ctgcggtggt ttttaatttc
    13981 ctaaattcca tgctagcttt aatggctata ttcatagggg ctggctatgt ggtcggattt
    14041 tggttactaa tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgtac
    14101 ttgagtacgg caaggcgacg ttgacgtggt ttgaatttga ttttcgaaga gtataaaatg
    14161 gtttgttttg gaaaggctag aactaaagaa tgacgcgtag gaagtctgtt tggtgaggag
    14221 gatagtttta tggagttttt tgataaattt catgccttgt gttttggatt tttagtacta
    14281 ataattgtca ttacagttcc ttatacgatt aaccatgggg ttttttttca aaatgaatct
    14341 gcattgattc ttgtaagtct tcttgtaacc tcgctgagtg ttgcttatgc tagaaagttt
    14401 gaaatgattt cttttgggat gttaagcaag aaacaacttt tgcttttcat tgcaatcttt
    14461 cttctaagtg tacttgagac gctggtttat attcatttct tcgctgtttc ttctggctca
    14521 ggggtccaac acttggcgga agtcagcaga ggaatttccc tgtctttgat tttgactacc
    14581 tcagtttttg gccccatcca ggaggaactc attttcagag gacttcttca aggtgcggtt
    14641 tttgacaatt cttggttagg gcttgtgcta acttcctctc tcttttcttt catgcatgga
    14701 ccttctaatg tcccttcgtt tattttttat ctacttgggg gtttgttgct gggctttgct
    14761 tataaaaaga gtcaaaacct atgggtttct actctagtcc acatgtttta caacagttgg
    14821 ccactcctat attatttata aaaattatga aaaggtaagc agaagatggt gcttaccttt
    14881 ttcaagctat aatgataccc aagccaatcc agaggctttt ctttgagaat cgggttagag
    14941 tggttgacga ataggccaaa aactagtaga atagtaagga aactttatac ggaggaaaga
    15001 aatggatttg ggtgataatg agctaacact gactcccata cctgggaaaa gtggcaaggc
    15061 ttatatgggt agctatcctg acgggaagcg catctttgta aaaatgaaca cctctccaat
    15121 cctacctggt ctagctagag aacaaattgc tccacaatta ttatggagtc gtcgtttggc
    15181 agatgggcgt gatatgtgtg ctcaagaatg gttgacaggc aagatattga ccccctatga
    15241 tatgaatcgt aagcaaatcg tcaatatttt aacccgtctt catcgctcac gtccgttgat
    15301 gacacaattg agtcgtttgg gctatgccat ggaaacacct gtagatttac tacagtcttg
    15361 gcaggaaacg gctccagatg ctttgcgtaa aaatcatttt atcagtgaag tgatggctga
    15421 tttacgtcag actattccag gatttagaga ggaccatgcg accattgtcc atggagatgt
    15481 acgacatagt aattggattg agacagatag tggcttgatt tatttagtag attgggattc
    15541 ggttcgcttg accgatcgca tgtttgatgt ggcccatatg ctctgccatt atatttcaga
    15601 acatcagtgg aaggaatggt tgacctacta cggttacaag tacaatcaaa cggtattaag
    15661 taaattgtat tggtatggtc aattgtctta tttgagtcag atttccaagt attatatgaa
    15721 ccaagattta gaaaatgtca atcgggagat tcatggtttg cgtcatttcc gagacaagta
    15781 tggaaagaga agatgagagt tagaaatcgt aaaggggcaa cagaattact agaggcaaat
    15841 ccccagtatg tggtcctcaa tcccttggaa gccaaggcaa aatggcggga cttgtttggc
    15901 aatgataatc ccattcatgt ggaagttgga agtggaaagg gtgcctttgt ttcaggtatg
    15961 gccaagcaaa accctgacat caactatatc gggattgata ttcaaaagtc tgttttgagc
    16021 tacgctttgg acaaggtgct tgaagttgga gtgcctaaca tcaagctctt gtgggtagat
    16081 ggttctgact taactgacta ctttgaagac ggtgagattg atcgcttgta tctgaacttt
    16141 tcagatccat ggccgaaaaa acgccatgaa aagcgtcgtt tgacctacaa gaccttcttg
    16201 gataccttca aacgtatctt gcctgaaaat ggagaaattc atttcaagac ggataaccgt
    16261 ggcttgtttg agtacagttt agtgagcttt tctcaatatg gcatgaaact caatggtgtc
    16321 tggttagatt tgcatgccag tgattttgaa ggcaatgtca tgacagaata cgagcaaaaa
    16381 ttctcaaaca aggggcaagt tatctaccga gttgaggcag aattttaaga gatagcctaa
    16441 aattaggctg tacaagtgct tttgctttac ataagttggc aaacgtgcta tactgatagt
    16501 aagaatatga aaagtgaggc ggggaaatat cttcgcctct tgcttatgag gaggtggacg
    16561 caatcgcaac aatcgtagaa ttagtcagag aagttgtaga acctgtcata gaagctcctt
    16621 ttgaactcgt ggatatcgag tatggaaaga ttggcagtga catgattctc agtatttttg
    16681 tagataaacc cgaaggaatt accttgaacg acacggcaga cttgacagaa atgatcagtc
    16741 ctgtcctaga caccatcaag ccagatccct tcccagaaca atatttccta gaaattacca
    16801 gtccaggttt ggaacgtcct ttgaaaacca aggatgccgt cgctggagcg gttggaaaat
    16861 acatccatgt cgggctctac caagccatcg ataagcaaaa ggtctttgaa ggaaccttgt
    16921 tggccttcga agaggacgag ttgactatgg aatatatgga caagacgcgt aagaaaaccg
    16981 tccaaattcc atacagttta gtatcaaaag cacgtttagc agttaaatta tagaaaaaga
    17041 aaggatagct tttgaggatt caaaagtgaa gaaaacatga gtaaagaaat gctagaggcc
    17101 ttccgcattt tggaagaaga caagggaatc aaaaaagaag atatcatcga cgcagtagta
    17161 gagtcgcttc gttccgctta tcgcagacgc tatggtcagt cagacagcgt agctattgac
    17221 ttcaacgaaa aaacaggtga ctttacagtt tatactgtcc gtgaagttgt tgatgaagta
    17281 tttgatagcc gtttggaaat cagcttgaaa gatgctcttg ccattaattc agcttatgaa
    17341 cttggagaca aaatcaagtt tgaagaagca ccagctgagt ttggtcgtgt agcagcccaa
    17401 tctgccaaac aaaccatcat ggaaaaaatg cgcaagcaaa cacgtgccat cacttacaat
    17461 acttacaaag aacatgagca agaaatcatg tctggtacag tagaacgctt tgacaaccgc
    17521 tttatctatg tcaaccttgg tagcatcgaa gcccaattgt caaaacaaga ccaaattcct
    17581 ggagaagttt ttgcttctca tgatcgtatc gaagtttatg tttacaaggt tgaagacaac
    17641 cctcgtggtg tgaacgtctt tgttagccgt agccatccag aaatgatcaa acgtttgatg
    17701 gagcaagaaa ttccagaagt ttatgatgga actgttgaaa tcatgagcgt ggctcgtgaa
    17761 gcaggtgacc gtacgaaggt tgctgttcgt agccacaatc caaacgtgga tgctatcggt
    17821 acaatcgttg gacgtggtgg tgctaatatc aagaagatta ctagcaaatt ccacccagct
    17881 cgttacgatg ctaaaaatga ccgcatggta ccaatcgaag aaaatatcga tgttatcgag
    17941 tgggtagcag atccagctga atttatctac aatgccatcg ctcctgctga ggttgaccaa
    18001 gttatctttg atgaaaacga cagcaaacgt gccttggtgg ttgttccaga taacaagctt
    18061 tctcttgcca ttggtcgtcg tggacaaaac gtgcgcttgg cggctcactt gactggttac
    18121 cgtatcgata tcaagtctgc tagcgaattt gaagccatgg aagacgctgc ttcagtagag
    18181 ttggaagtag aaaacgatac tgtagaagaa taaaagctgc tagaggaggg aaagatgaaa
    18241 acaagaaaaa tccctttgcg caagtctgtt gtgtctaacg aagtgattga taagcgtgat
    18301 ttgctccgca ttgtcaagaa caaggaagga caagtcttta ttgatcctac gggcaaggcc
    18361 aatggccgcg gcgcttatat caaactagac aatgcagaag ccctagaggc gaaaaagaag
    18421 aaggtcttta accgcagttt tagcatggaa gtggaagaaa gcttttatga cgagttgatc
    18481 gcttatgtgg atcacaaagt gaaaagaaga gagttgggac ttgaataagc aaaagataag
    18541 taatctcttg gggcttgctc agcgagcagg gcgcatcata tcgggtgaag aattggtggt
    18601 caaggccatt caagacggca aggccaagtt ggtctttcta gctcatgatg ctggacccaa
    18661 tctgaccaag aagattcaag ataaaagtca ttattatcaa gtagaaattg taaccgtgtt
    18721 ttcaacactg gaattaagca tagcagtcgg gaaatcgaga aaggttttgg ctgtaacaga
    18781 tgctggattt acaaagaaaa tgaggtctct tatggaatag aagaggagga catgatttgt
    18841 ctaagaaaag attgtacgaa atcgcaaaag aacttggaaa agaaagtaaa gaagttgtag
    18901 cgcgtgcaaa agagttgggc ttggatgtga aaagccactc atcaagtgtg gaagaagctg
    18961 tcgctgcaaa aattgctgcc agctttaagc ctgcagctgc tccgaaagta gaagcaaaac
    19021 ctgcagcacc aaaagtaagt gcagaaaaga aagccgaaaa atctgagcca gctaaaccag
    19081 ctgtagctaa ggaagaggca aaaccggctg agccagttgc tccgaaaaca gaaaaagtag
    19141 cagcgaaacc gcaaagccgt aatttcaagg ctgagcgtga agcccgtgct aaagagcagg
    19201 cagaacgacg caagcaaaat aagggcaata accgtgacca acaacaaaac ggaaaccgtc
    19261 agaaaaacga cggccgtaat ggtggaaaac aaggtcaaag caaccgcgac aatcgtcgct
    19321 ttaatgacca agctaagaag cagcaaggtc agcaaaaacg tagaaatgag cgccgtcagc
    19381 aagaggacaa acgttcaaat caagtggctc cacgtattga ctttaaagcc cgtgcagcag
    19441 ccctaaaagc agagcaaaat gcagagtacg ctcgttcaag tgaggaacgc ttcaagcagt
    19501 atcaggctgc taaagaagcc ttggctcaag ctaacaaacg caaggaacca gaggaaatct
    19561 ttgaagaagc ggctaagtta gctgaacaag cacagcaagt tcaagcagtg gttgaagtcg
    19621 tccctgagaa aaaagaacct gcagtggata cacgtcgtaa aaaacaagct cgaccagaca
    19681 aaaatcgtga cgattatgat catgaagaag atggtcctag aaaacaacaa aagaatcgaa
    19741 gtagtcaaaa tcaagtgaga aatcaaaaga atagtaactg gaataacaac aaaaagaaca
    19801 aaaaaggcaa taacaagaac aaccgtaatc agactccaaa acctgttacg gagcgtaaat
    19861 tccatgaatt gccaacagaa tttgaatata cagatggtat gaccgttgcg gaaatcgcaa
    19921 aacgtatcaa acgtgaacca gctgaaatcg ttaagaaact tttcatgatg ggtgtcatgg
    19981 ccacacaaaa ccaatccttg gatggggaaa caattgaact cctcatggtg gattacggta
    20041 tcgaagccaa acaaaaggtt gaagtggata atgctgacat cgaacgtttc tttgtcgaag
    20101 atggttatct caatgaagat gaattggttg agcgtccacc agttgttact atcatgggac
    20161 acgttgacca cggtaaaaca acccttttgg atactcttcg taactcacgt gttgcgacag
    20221 gtgaagcagg tggtattact cagcatatcg gtgcctacca aatcgtggaa aatggtaaga
    20281 agattacctt ccttgataca ccaggacacg cggcctttac atcaatgcgt gcgcgtggtg
    20341 cttctgttac cgatattacg atcttggtcg tagcggcaga tgacggggtt atgcctcaga
    20401 ctattgaagc catcaaccac tcaaaagcag ctaacgttcc aatcatcgta gccattaaca
    20461 agattgataa accaggtgct aacccagaac gcgttatcgg tgaattggca gagcatggtg
    20521 tgatgtcaac cgcttggggt ggagattctg aatttgttga aatctcagct aaattcaacc
    20581 aaaatatcga agaattgttg gaaacagtcc ttcttgtagc tgaaatccaa gaactcaagg
    20641 cagacccaac agtgcgtgca atcggtacgg ttatcgaagc gcgcttggat aaaggaaaag
    20701 gtgcggtcgc aacccttctt gtacaacaag gtaccttgaa tgttcaagac ccaatcgttg
    20761 tcggaaatac cttcggtcgt gtccgtgcta tgaccaacga ccttggtcgt cgtgttaaag
    20821 ttgctggacc atcaacacca gtctctatca caggtttgaa cgaagcaccg atggcgggtg
    20881 accactttgc cgtttacgag gatgaaaaat ctgcgcgtgc agcaggtgaa gagcgtgcca
    20941 aacgtgccct catgaaacaa cgtcaagcta cccaacgtgt tagccttgaa aacctctttg
    21001 atacccttaa agctggggaa ctcaaatctg ttaatgttat catcaaggct gatgtacaag
    21061 gttctgttga agccctttct gcctcacttc aaaagattga cgtggaaggt gtcaaagtga
    21121 ctatcgtcca ctcagcggtc ggtgctatca acgaatcaga cgtgaccctt gccgaagctt
    21181 caaatgcctt tatcgttggt ttcaacgtac gccctacacc acaagctcgt caacaagcag
    21241 aagctgacga tgtggaaatc cgtcttcaca gcattatcta caaggttatc gaagagatgg
    21301 aagaagctat gaaagggatg cttgatccag aatttgaaga aaaagttatt ggtgaagcgg
    21361 ttatccgtga aaccttcaag gtgtctaaag tgggaactat cggtggattt atggttatca
    21421 acggtaaggt tgcccgtgac tctaaagtcc gtgttatccg tgatggtgtc gttatctatg
    21481 atggtgaact cgcaagcttg aaacactata aagacgacgt taaggaagtt acaaacggcc
    21541 gtgaaggtgg attgatgatc gactgctaca atgatattaa gatggatgat gtgattgagg
    21601 cgtatgtcat ggaagaaatc aagagataag attttttgct cctttcttag gtggtgaggg
    21661 acgcaagcaa accgatggtt tcattgctta tttttgagcc tagggtctca aaaatcccct
    21721 gtgatgggac tgataaatca gttccatcac tttcaccacg gcgaaagaag cagatgactt
    21781 caaattgaac ttcgtttcaa tttaaactga aaatcaagaa gtttaaaata gctaggtctg
    21841 ctggcctagc ttttggttca aagtagagaa aggaatatca tggcaaatca tttccgtaca
    21901 gatcgtgtgg gcatggaaat caagcgtgaa gtcaatgaga ttttgcaaaa gaaagtccgt
    21961 gatccacgtg tccaaggtgt gaccatcaca gatgttcaga tgctgggtga cttgtctgtt
    22021 gccaaggttt attacaccat tttgagtaac cttgcttcgg ataaccaaaa agcccaaatc
    22081 gggcttgaaa aagcaactgg taccatcaaa cgtgaacttg gtcgcaattt gaaattgtac
    22141 aaaatcccag atttgacctt cgtcaaagac gagtccatcg agtatggaaa caagattgac
    22201 gagatgctac gcaatctgga taagaactaa agaagagggg ttgcccctct tttttggtgg
    22261 aggaaaatag gttgaatttg aaatggaaaa atattctttt ataatagttt gaaactagaa
    22321 tagtacgcct ctacttctaa aa
//
LOCUS       DAVBNZ010000033        22095 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000033 DAVBNZ010000000
VERSION     DAVBNZ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.033"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(1..245)
                     /locus_tag="VQ860_001328"
                     /pseudo
     CDS             complement(1..245)
                     /locus_tag="VQ860_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(629..1825)
                     /gene="tuf"
                     /locus_tag="VQ860_001329"
     CDS             complement(629..1825)
                     /gene="tuf"
                     /locus_tag="VQ860_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3119754.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2701..3570)
                     /locus_tag="VQ860_001330"
     CDS             complement(2701..3570)
                     /locus_tag="VQ860_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3119755.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3793..4473)
                     /locus_tag="VQ860_001331"
     CDS             complement(3793..4473)
                     /locus_tag="VQ860_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET3119756.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(4431..5537)
                     /locus_tag="VQ860_001332"
     CDS             complement(4431..5537)
                     /locus_tag="VQ860_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET3119757.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWVRSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELILENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5648..5902)
                     /locus_tag="VQ860_001333"
     CDS             complement(5648..5902)
                     /locus_tag="VQ860_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119758.1"
                     /translation="MLNVDQDFMSISKPNKSGSDWKKTFTVRTTNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(6260..6793)
                     /locus_tag="VQ860_001334"
     CDS             complement(6260..6793)
                     /locus_tag="VQ860_001334"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3119759.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     RAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6780..6995)
                     /locus_tag="VQ860_001335"
     CDS             complement(6780..6995)
                     /locus_tag="VQ860_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3119760.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCALPSVWAALKYIKVTLKKDDEL"
     gene            complement(6962..7105)
                     /locus_tag="VQ860_001336"
     CDS             complement(6962..7105)
                     /locus_tag="VQ860_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HET3119761.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            7339..9057
                     /locus_tag="VQ860_001337"
     CDS             7339..9057
                     /locus_tag="VQ860_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET3119762.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            9168..9515
                     /locus_tag="VQ860_001338"
     CDS             9168..9515
                     /locus_tag="VQ860_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3119763.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     SGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9793..10629)
                     /locus_tag="VQ860_001339"
     CDS             complement(9793..10629)
                     /locus_tag="VQ860_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3119764.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10642..11271)
                     /locus_tag="VQ860_001340"
     CDS             complement(10642..11271)
                     /locus_tag="VQ860_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3119765.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11281..11922)
                     /locus_tag="VQ860_001341"
     CDS             complement(11281..11922)
                     /locus_tag="VQ860_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3119766.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(12068..13297)
                     /locus_tag="VQ860_001342"
     CDS             complement(12068..13297)
                     /locus_tag="VQ860_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET3119767.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13287..14453)
                     /locus_tag="VQ860_001343"
     CDS             complement(13287..14453)
                     /locus_tag="VQ860_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3119768.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14597..15610
                     /locus_tag="VQ860_001344"
     CDS             14597..15610
                     /locus_tag="VQ860_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET3119769.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPNQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15655..16074)
                     /locus_tag="VQ860_001345"
     CDS             complement(15655..16074)
                     /locus_tag="VQ860_001345"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET3119770.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(16085..17491)
                     /gene="atpD"
                     /locus_tag="VQ860_001346"
     CDS             complement(16085..17491)
                     /gene="atpD"
                     /locus_tag="VQ860_001346"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET3119771.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17577..18455)
                     /locus_tag="VQ860_001347"
     CDS             complement(17577..18455)
                     /locus_tag="VQ860_001347"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET3119772.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18471..19976)
                     /locus_tag="VQ860_001348"
     CDS             complement(18471..19976)
                     /locus_tag="VQ860_001348"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET3119773.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19991..20527)
                     /locus_tag="VQ860_001349"
     CDS             complement(19991..20527)
                     /locus_tag="VQ860_001349"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET3119774.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20527..21021)
                     /gene="atpF"
                     /locus_tag="VQ860_001350"
     CDS             complement(20527..21021)
                     /gene="atpF"
                     /locus_tag="VQ860_001350"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET3119775.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(21035..21751)
                     /gene="atpB"
                     /locus_tag="VQ860_001351"
     CDS             complement(21035..21751)
                     /gene="atpB"
                     /locus_tag="VQ860_001351"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET3119776.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21786..21986)
                     /locus_tag="VQ860_001352"
     CDS             complement(21786..21986)
                     /locus_tag="VQ860_001352"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET3119777.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         6571 a         4737 c         4032 g         6755 t
ORIGIN      
        1 gtcatatatg catggttacg accaccacgt gtttcttgaa ggagagagtc gagtccgaac
       61 tcctcatatt tttttacgtt tcgccaaatc gttgtttgat tacagtctaa aagctctata
      121 atctcttaat aagatttgcc catcagacga aatagaacga tttgaaggcg tttatgatat
      181 ttagctgtac gagagtcttt taaaagtgtt ttgatggttt tgatttcttc tttagttgat
      241 ttcatattac tattgtataa tgctttttga tttgagtcta gtattatact cttcgaaaat
      301 ctcttcaaac cgcgtcagct tcgccttgtc gtatagatgt tactgacttc gtcagttcta
      361 tctacaacct aaaaacagtg ttttgaacag tctgcagcta actttctata acaaaatgaa
      421 ataagaacaa gacaaatcaa tcaagacaat caaatcgatt tctaacaatg ttttagaagt
      481 agatgtgtac tattctagtt tcaatatatt atagtttgct ctttgatttt cattgagtat
      541 tagttcaata tctaaaaaaa gaaccttgcc aagcaagatt cttttagtgt ctaacttaaa
      601 taattgttct tctgggaact aaatcgaatt aagcttcgat ttctgtaacc atacctgaac
      661 caacagtacg tccaccctca cggatagaga atgtagtacc ttgttctacg gcgattgggt
      721 gaatcaactc aacgtcgatt gtcacgttat caccaggcat taccatttca gtacctgctg
      781 gaagttcgat tgaacctgta acgtcagtag tacggaagta gaattgtgga cggtagttgt
      841 tgaagaatgg agtgtgacgt ccaccttctt ctttagtaag gatgtagact tcacctttga
      901 atttagtgtg tgggttgatt gaacctggtt tagcgataac ttgtccacgt tcgatttcat
      961 cacgttgaac accacgaaga aggacaccta cgttatctcc agcaagacct tcgtcaagtt
     1021 gtttacggaa catttcaaca ccagtaacaa ctgctttttg agtttcttct ttgataccaa
     1081 cgatttcgat ttcgtcgttg actttaacga taccacggtc gatacgtcct gaagcaactg
     1141 taccacgtcc agtaattgag aatacgtcct cgactggaag aagcaatggt ttgtcagtgt
     1201 cacgttctgg ttctgggata tactcatcaa ctgtgttcat caattccata acgatgtctt
     1261 cgtatttaga gtcaccttca agagctttaa gtgctgaacc ttggataact ggaagatcgt
     1321 cacctgggaa gtcgtattct gacaataggt cacggatttc catttcaacc aattcaagca
     1381 attcttcgtc gtcaaccaag tcaactttgt tcatgaagac gataaggtgt ttaacaccaa
     1441 cctgacgtga aagaaggatg tgctcacgag tttgtggcat tggtccgtca gttgaagcta
     1501 ctacaaggat agctccgtcc atttgagcag caccagtgat catattttta acgtagtccg
     1561 cgtgtcctgg agcgtcgatg tgagcgtagt gacgtttttc agtttcgtac tcaacgtgcg
     1621 cagtgttgat agtgataccg cgttcgcgtt cttctggagc agcatcgata gacgcatagt
     1681 ctttaggttg gttaactgat gaaggcaagc gacgtgccaa aacagttgtg atagctgcag
     1741 ttagggtagt tttaccgtgg tcaacgtgtc cgatagtacc aatgttaacg tgtggtttac
     1801 tacgatcgta tttttctttt gccatttgag taaaagcctc caataaaata tattttatag
     1861 atagacagta ggcaatacag tctaactttc cttactattt tatcaaattt cagctaaatt
     1921 gcaagtgttt tacaacgttt ttgtgaatta ttcttggtaa aaatttaact aactaataga
     1981 aagtactaaa tagacttatc cttcaaggag ttttcagcat tatccatcca ctcacttgct
     2041 gaaaatgtaa acagtctctg gtttatatag taaaatgaaa caagaatagg gcaaatcgat
     2101 caggacaatc aaatcgattt ctaaaaatgt tttagaagta gaggtgtact attctagttt
     2161 caatctacta tacaacctca aaactgtgtt ttgaacaacc tgcggctagc ttcttagttt
     2221 gccctttgat tttcattgag tataaaattg cagataaaac gataacaatc ataggactca
     2281 gcagagtcaa tgtaggtcga agaatagccc ccctaatcgc ttattttata gcaaaatgaa
     2341 atagaaactg aacattttgt tgaggaaggt aaatcaattc ctcacaatgt ttgagaaaga
     2401 agggaggact attccaactt caacccacta ttaatatata atagaatgaa aactgcacaa
     2461 tttgattgga gaattcaaac caatttctaa caatgtttta gaaacaaggg tctattattt
     2521 caactgcaac ctactatagc ccattgaagc tggaatagcc cactgagact tctaaaccac
     2581 tgctggagag gagtttgttt agagtttctt tcatttccct aaaaaatcaa aaagagagaa
     2641 ccagtctgat cctctcttac ttatagatgg tgctcactca aatgttaaag gagctatttc
     2701 ttagagataa aggaatttga atacagctac tgccgcaatt gctgctgcga taggtgctac
     2761 tactggtacc caagaatacc accattttga atcgccttta tgctcaccaa gaactgattt
     2821 tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg gctgggttca aggcgggtcc
     2881 tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg aatccaagtg ccaagtgagc
     2941 cacagaaagt cctgaagcag tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa
     3001 atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg aattgaagca cttcagcacc
     3061 aaagaagttt ttagtcaaac caagagctgc aaagaacaaa acaaatgaac caacaaactc
     3121 attaatcaaa ccattgacag ttgctgcata gcgactttct tttgtaccat ggtcaatact
     3181 tgaaatagtt gagaaagttc ccaagatgtt atttggtttt tcagttttca agtagaatgg
     3241 acggtatgtt gccacaacta aggcttggcc aaagatagcc cccaagactt gcgcgataat
     3301 gtaaggtacc acttgtgccc aagggaaaag accgctaact gcaagcccta gagtgaaagc
     3361 agggttgatg tgattcccag atacgttacc aaacatcaag gctgggatca taacccccat
     3421 accataacca acagcgatga cgatccagcc actttggtga cctttcgtac ctttaagttc
     3481 aacgttggca actgcaccat tcccaagaat gatcaaaatg gcagttccca aaaattcagt
     3541 ggcatacttc agtgcccatg tgaaatccat ttgctagatt ctccttaaaa ttttttagat
     3601 attccttatt ttatcaattt ttaccctatt tagcaactga tttctggaaa tatttttaaa
     3661 aaaataggat tcatagtttc ctagttcaac gtacttgtaa gcgtttttat tcttcacgaa
     3721 agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg atcttttcct tgttcctaga
     3781 ttctaaaatc tattattttt catcttcttt tttcttgaag aatcctaatc ctagaccagc
     3841 taacaaggtc atgataccag cactagccaa ggtagcatta gcttctgtac ctgtgtttgg
     3901 caattcctct ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt
     3961 ttcagttttt ggagtacctg gttctggagt tggtttatct ggtgttggag tctcttgatt
     4021 tggtagttct gggtttggtg tcggaacact tggatgctct ggatttggtt gtgggattgg
     4081 tttttctgga gtcggttcac ctggagtacc tggttcctga ggacttggaa tttctggttt
     4141 ttctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta tttctttatc
     4201 actagagtct gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt
     4261 gtcaatctta ccagatataa cctcgtccca gtttcctgtt gtccattcac cgtaggttac
     4321 aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc
     4381 ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt
     4441 cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta
     4501 atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat
     4561 gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata
     4621 gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct
     4681 gccaacttct cttggctacc ttctttatag taattggctg ttactgtagc agtggttggc
     4741 gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt
     4801 aaacttgcag aatttgtatc tgcttcttta aaagtataat attttccgtc agtagtagtc
     4861 atgctactga gttttttatc tgtgacattg tagctggtac caatcagttg ttttttattg
     4921 gtaatgtagg ttccgtcact ttctttttct ccaattccag tatcattttt caatgatagc
     4981 aaacgccctt gttcatcaac atagcgaact ttcacatttt ctaagattag ttctgccaat
     5041 tctgaggttt ttttcttttt cttgatttct tcggttattt tccctttctc ttcttcggga
     5101 atatttagtt ttggaatgat tttttcaaca acggttcgtg atggttccac agtatcttgg
     5161 atgactgaaa agtcagctag aattgggaga ttatactgaa cacggtgact ttgagtgttt
     5221 actcctactc tttcattatt ctctgaaaat acttgtacgg tataagaaac aacatctttt
     5281 cctaatagaa catccccagt agagaaatag ccgccttttc ctagtttgct atctccagag
     5341 cccacttctt tcctaatctt atcagatagt tttttaccag tcagtacatt cgttcgcaca
     5401 atccctttgt ctacccctac aaagtgggag aactttttga actcttcaga accagatcta
     5461 acccaaccat tattaagggc atttgctttt gtatttgtat tctctctcaa aagtttggcg
     5521 attagaatta tattcatcgg cacttagagt tgctgctata tctgactctt gaataccaac
     5581 ttccttacta ccatttctag cggcagtata tgtgtattta tctgtttcta cttctagctg
     5641 attatcctta acatgatagg taattttcac ctggtataag agtcttcagt agtttatata
     5701 ctctgtcatc atctttagct ttagaagcag ctgagtttag ccaagttggg gtattaggag
     5761 tatctttatc aacctgtttc aagacattat tcaagtcatt tgctagccta ttggttgtcc
     5821 tcactgtgaa agttttcttc cagtctgaac cacttttatt aggcttagat atgctcatga
     5881 aatcctggtc aacattcaac acaatatcgc cttgtttttt agcatcttcc gttgcttctg
     5941 cttcaaattg atcatggagt ttttgttgct ctggtgtata gtttttttat ttacacgatt
     6001 taatgtacta ttttttattt tagtattaag aactccatta atacgatttt taaattctgc
     6061 ttcaaaaaat cccttaattt gttggtgcgc aagttcaaca ttcaaacctt tcttatacaa
     6121 gtcttcattc tgatacaagt cttcattctg aacgatttcg gctacacggt gaatggtttg
     6181 attgtatacc gtcttctctt aaccagcagt atccttagtt ttaatgacta ctcgataggt
     6241 tcctttagaa ccgttatagt catctagttt taaaaaagca ttccaaacat tcaaaaatag
     6301 ttggaacttc ccttaataaa tccgtcactt tctttttcaa gatagcccaa gcttgctcaa
     6361 taggattcaa atccggtgaa taaggtggta gaggtaagaa aaagtgttta tcttggatgc
     6421 agagttcatc caaaatgttc ttgggatgaa aactagcatt gcccatgaca ataacatgag
     6481 gtgtcttcaa agcaggtagg agttgcgttt tgaaccactc cacaaagaaa tcgcttgtca
     6541 tgcttttctt gtaaatcatg ggagctataa actctccgtc tacttgtcct gcaacaattg
     6601 aagttcgctc aaaacgacgt ccgctaatct tttcatagac tttctcccct ctaggagccc
     6661 gtgcataagg acgatagagg tagcggtcga ttcctgtttc atcaatatat acgattggta
     6721 aatcttttag gttatccaaa atatcaagaa actcagcgac tttctctggc tcttgttcct
     6781 taaagctcgt catctttttt taaagtgacc ttaatatact ttaaagctgc ccatacggag
     6841 ggcagagcac aatcaaaatg tgccgcaatt tcccgtaaaa aagcatctgg atgagcctct
     6901 acaaaggctt tcaattcctc taaaggaatc tttcggtttt tgacgactcg ctttttcctc
     6961 tctatgtgtc cttgttcaca tctttctttt cccacgtgaa gagagttctg acgccaacac
     7021 caaaaaactt ggctgcctcg acatggctgt gcccctcttt gatggaatct aatgctcgct
     7081 gtttaaaatc agtactatat gccatagctt tattataata tgcttgttta aaactaagca
     7141 actatatcaa tgttttgtta ttagaagact tacttttttt actgaaatcg aatttttcct
     7201 aacctcaaca tcatataacc ccaaaattca atctgacctg gtttgaagag atgttcgaag
     7261 cagataaggt tttactaaaa ctaaaaaaaa tgatataatc aaactgatta aatgttttaa
     7321 aaataaagga gaatttgaat gtcttaccaa gaaaattacc agaaatgggt tgattttgtg
     7381 gagcttcctg actaccttcg tcaagatttg gaaaatatgg acgaaaaaac taaggaagat
     7441 gccttctata caaatcttga atttggtact gcaggtatgc gtggcttggt tggtgctggt
     7501 acaaaccgta tcaacatcta cgttgttcgc caagctactg aaggattggc tcgtttgatt
     7561 gagtcaaaag gtggaaacga gaaagaacgc ggtgtagcaa ttgcctacga tagccgtcac
     7621 ttctcacctg agtttgcctt tgaatctgcg gcagttcttg ctaaacacgg catcaaatct
     7681 tacgtatttg aaagccttcg tccaactcca gaactatcat ttgcagttcg tcatctcaac
     7741 tgtttcgcag gtatcatggt cacagccagc cacaaccctg ctccatttaa cggttacaag
     7801 gtttacggtg aagacggtgg acaaatgcct ccacacgatg cggacgcttt gactacttat
     7861 atccgtgcaa tcgaaaaccc atttgcagtt gaagttgctg atgtggaaac tgaaaaagct
     7921 tctggcttga ttgaagttat cggcgaagct gttgacgtag aataccttaa agaggttaag
     7981 gacgtaaaca tcaacccagc cttgattgaa gaatttggta aagacatgaa gattgtctac
     8041 acaccacttc atggtactgg tgaaatgttg gctcgtcgtg ctcttgccca agcaggattt
     8101 gactctgttc aagttgttga agcgcaagca actgctgacc cagacttctc aactgtaaca
     8161 tctccaaacc cagaaagcca agcagccttt gcccttgctg aagaacttgg tcgtcaagtt
     8221 ggtgcagatg ttcttgtcgc aactgaccca gacgctgacc gtgttggtgt tgaagttctt
     8281 caaaaagatg gtagctacct caacctttca ggtaaccaaa tcggtgctat catggctaaa
     8341 tacatcttgg aagctcacaa aaacgctgga actcttcctg aaaatgccgc tctctgcaaa
     8401 tctatcgttt caactgactt ggtaacgaag attgctgaaa gctacggcgc aactatgttc
     8461 aacgtcttga caggtttcaa atttatcgct gaaaaaatcc aagaattcga agaaaaacac
     8521 aaccacactt acatgatggg atttgaagaa agcttcggtt acttgattaa accatttgta
     8581 cgtgataaag atgccatcca agccgttctt gtcgttgctg aacttgctgc ctactaccgt
     8641 tctcgtggtt tgacacttgc tgacggtatc gaagaaatct ataaagaata tggctactac
     8701 gcagaaaaaa caatctctgt tactctttca ggtgtcgatg gtgctgaaca aatcaaagcg
     8761 attatggcta aattccgcaa caatgctcca acagaatgga acgcaacagc tatcactgtc
     8821 gtagaagact tcaaggcaca aactgctact gttgctgacg gtactgttac aaacttgaca
     8881 actcctccaa gtgatgtgtt gaaatacaca cttgctgacg gttcatggat tgccgttcgc
     8941 ccttcaggta cagaaccaaa aatcaagttc tacattgcag ttgtagggga aaccaacgaa
     9001 gaatcacaag ctaagattgc taacatcgaa gcagaaatca atgcatttgt aaaataaaga
     9061 cctataaaag atgagaccaa ccaacctcat cttttttcgt atcaaatcta agcaatttta
     9121 gaaactttat ggcatactag acttatcaat gaaagcgagg taatctcatg gaacaatttt
     9181 tagataacat caaagacctt gaagtcacta cagttgtgcg tgcgcaagaa gctcttgata
     9241 aaaaagaaac tgcaaccttc tttatcggtc gcaaaacttg cccttactgc cgtaaatttt
     9301 caggtacatt gtcaggtgtc gtagctgaaa ccaaagctca catttacttc atcaatagtg
     9361 aagaaccaag ccaactcaat gatttgcaag cattccgctc acgctatgga atcccaactg
     9421 taccaggttt tgttcatatt acagatggac aaatcaacgt ccgttgcgac tcttcaatgt
     9481 cagcacaaga aatcaaagat ttcgcaggat tgtaaaaaat cagctaacaa gtcttaaaat
     9541 cacaaaaacg cataatgtaa ggtgcaaaaa ccttgatatt atgcgtttta ttgttcctaa
     9601 aacagttaca tcagcatttc attacagaac attttaattt tggaagtcaa atcaattttt
     9661 aacaatgttt tagaaatcac agtgggctat tccatattca attatccaga ttcaatcgct
     9721 attatcgttt tcctagatta caaaaaaact acgttttgct aatcaaaacg cagtttcagc
     9781 cactatttta tcttactgtc cttcttttac ttctttggtt gctacatctt ctccaaacca
     9841 tttttgactg atttcttgga acttgccgtc cttgtaaaga ctagaaaaag cttcatttat
     9901 cttcttaacc aagtttgtat cttccttacg ggctccaacc gcaaaagctt ctgtttctag
     9961 tccaactgta aagacattat aatcgtttaa aacaccttct gcttctaaat aataatttgc
    10021 atagacacgg tcaatcaata gaccatcaat tcgatcgttt ttcaaatcaa tcaaggcttc
    10081 attaaaggtt tggtattgat tcgcttcctt attagcgaca atattcttca aaatttctgg
    10141 atttgcttca aagtccgcat aaccagatga accagcttga gctcctaatg tctttccagt
    10201 catatccttt gcagtcgtga taccagatga tttcttcgta accaatacct gctcattctt
    10261 catatatgag ttactgaaag ccaccttttc acggcgttcg tctgtagcgg aatagccatt
    10321 ccaaatcaga tcaatcgttc cttttgtcaa ttcagcttct ttcaaatccc aatcaatcgg
    10381 ttgccaattt accgtgattc cgtatttttc aaaaacagct gtagctaaat caatatcaaa
    10441 tcctgcataa gaaccatctt tctgagcaaa tcccattgga acaaaagtac tatcaaatcc
    10501 aatagtaata gacttgttag actggtactt tgaccaatta tctccactag tttcgctaga
    10561 atttttccca caagctacta agaacaaagc agtcatcaga ctgactaata caagcatcca
    10621 ttttttcatc catttttcct cctatttagg ttctactttc aataatacat ctgcgatatt
    10681 ttcagcaaac tgcaaatcat gggtaaccac aatctgggtc atcccaagtt ccctattttg
    10741 caagattagc ttctccactt ccaaacgtaa ttctggatcc agggcagaag ttggttcatc
    10801 gtagccaatg atttctgggt caatcatcat agcacgcgcc aaagccaccc gctgcttttg
    10861 cccaccagat agtgagaaag gataggcctc tgcgtgtcct cctagtccta actgttccaa
    10921 gagtccactc gccttcttct cagcctcttc ctgcttcatt cccatggtct tcacaggcga
    10981 taaagtcaaa ttttccagaa ctgatagatg aggaaatagt tgaaaatctt ggaagacaaa
    11041 tcccagtagg ttgcgcttct gcaattcatc tagctctaaa ggttgtccat tataaaagat
    11101 ttgccctgaa tcaatggttt caagacctgc aagcatacgt aaaagagttg tcttacctcc
    11161 accagaaggt ccaacgatag ccaggatttg cttttcagga atacttagac tgaaatcaga
    11221 caggatttgt ttgtctccaa agactttatt gatatttcgt aattctaaca tagctgcccc
    11281 ctatctataa taactgtact ttttctcaac ttttttggaa ataattgtca caatcccaat
    11341 taaaatcaag taaatggctc ctgccaagaa cataggaacc agactagcat cgcggttagc
    11401 agctgttcga ctagccaaga taaggtctga aattccgaga gcatagacca aagaagtatc
    11461 cttgaccaaa ctcataactt cattaaagac actaggaaga acgatcttgg tcacttgggg
    11521 caagataata tagcgcactc tgtcaaaagg gctaaacttc aagaccttgg cagcctcata
    11581 ctgtcctctt ggaatagtgt caattccccc acggaaaatt tctgcaaagt aagctgcata
    11641 gttgagaaca aaggcaataa tagctgcagg aaggcgatct aaacgaatcc caatacttgg
    11701 gagcacataa tagataaaaa tcagttgcaa gagtaagggg gttcctcgca taacccagat
    11761 gtaaatgtta atcagataat ggaggggctt ccaatggact tgcaaggcaa aggcaatcaa
    11821 aacgcccaag ggaatcgaaa atagcaagac cagtgcaaag acctgtacag tcgtgctcgc
    11881 accattcagt aaactcggta atatctcaaa taaataagac atactgcacc tcctaaaagt
    11941 aattgttcct attatagcat gaataaacaa gattaccaag tatttttgta aaaagattct
    12001 accatataca aataaaaacc gtagctatca aaagagataa actacagttc tatatgttta
    12061 aacattctta caatctctca aacagttctt gcatttgcac atcatctgga accagtttta
    12121 agtaagtgtg agcatggact tttgcttctt caaaatgtcc caattcacgc aagagataga
    12181 tatagtgttc cagaaattct ggattgtcct tcaaatctcc tgtcaactct tgataatgct
    12241 cataagcagt atccaaatcg tccatttctt gataagaacg agcaatcatc cacttggtca
    12301 aaagattttc tggctcctca ctctgcaagt ctagaatatc ctcataacgc tcctgctcca
    12361 gataaatagt ggctaaacga agcaagattt cttctgtatc ctcagcgtct tcttttgcag
    12421 taaggagata attttctgca ccactagcat catgcaattc ataagaaaat tgtgaagcag
    12481 ctagcaagag gcgagtttca aagggatttt tctctaatcc ttgcttagcg atacgcaggg
    12541 cttcttgaac ttgatgttcc ttatgtaaag cctgactgta cccatactca tagccttcaa
    12601 agtcaggaga aatggtatca agctgcttaa agtagagggt ggctttttga tattcttctt
    12661 gatcaaaata aagactggcc aactcaaaag ctgttaagtc atcgtattct aactccaggg
    12721 ctttttctaa aaactcagta gccgtttcaa atttccctaa ctgagcatag gcaaagccaa
    12781 ttcgttgata ggtggaaatg cccgtttgct cataaatcga gcgattatct aactgggcat
    12841 aggcttgaat agccgcttgg taattttcca actcactatc caactctgcc aaacccaata
    12901 tcaagagaga atcctctgag taggtcaagg cctccaataa tttctcacgt gccacatctg
    12961 tcaaaccttc cagctggtaa aggtctgcct tcagagccaa agacgagaca taccagtcac
    13021 tgtcagcttg gatttcctca agataggtaa aggcttcttc tatttgacca tcctcgctag
    13081 caattgcagc tagattaaga tgaacctctg gaaaatcctc tacaattttc aggtaaattt
    13141 ccttggcctg aggatagaaa ccaatccctt caagataagt tgccaactca tacagaagat
    13201 cacttgaatc attttctaaa gctttggcga aataatgctc agccttagtt aaatcttgct
    13261 cctccaaagc ctgtaacatc tgttgactat tgttcactct tgacttcctc accctctaat
    13321 tcatatagac cactgactac cttataccat tcgaaaatgg ctgaaatgac aaccttagca
    13381 gaggcataaa ccggaatacc aagtaaaact ccccagatac caaacataga tcctgaagtt
    13441 aacaaaacaa agagaacatt aataggatgg atgtttaatt gacttcccaa aatcaatgga
    13501 gagacaaaac ggccttcaat agtttgttct acaataaaga caatcactac tttcaaaagc
    13561 atgactggac cagcaatcaa acccaatact agggcaggaa gcatggctag aaagctacca
    13621 agataaggga ccagatttaa aataccagca gtaaccccca gcgtaaccgc atagcgtaga
    13681 ccaataatct tgaagaagat gataaacatt actgctacaa taatagccac tgtcacttgc
    13741 cctcgaacat agttggacaa ctgttgattc acatctgata gaacttgtcc aacaggttcc
    13801 ttcaattttc ttggaatgaa ttgggtcaaa tagttacgca agcctttccc atcacgcaag
    13861 agataaaaga gcatgaaagg aacgataatc aaggcaacaa tcacttgaga agctccgcta
    13921 ataaaggcac tcacccagtt gactgcctga gatgaaacct tacttgccaa aactgtagcc
    13981 tggctagaaa aattggtcaa aacttgctct aattgaggtc tgaaatcatc tggcaggtgc
    14041 tgggctacca atccattaac aatcctatct atatcttcta agtaaacagg aacgtttctt
    14101 gcaaaggtca aaacctgacg ttgcagattt ggaatggcga ctgccaagcc ccaaatgata
    14161 aagagagcga tgataacaaa gacaatagtg atagctataa cacgattaac cttatgcttc
    14221 tccatccaat caacaatagg attcaacaaa taatataaca aaccagacaa aatgactggc
    14281 aacatcacaa ctgctaaaaa gtctaaaaca ggtgaaaata gaaaactaat cttacttaaa
    14341 ataaaaagat tcagtcccaa taataaggtt actaaaaata ccgtaattgc cttgttatct
    14401 aaaaaccact tgaaaaacca agataggcta aaatgtttct ctttttgctc cataaatact
    14461 tcctttctat tgtcctctca ttataccatt tttgaaacaa aataactctt ttttaaagtg
    14521 cttacatcta attggatatc tttaatttac ttgtttttgt gatataatag tcttatcttt
    14581 acacagaggt atagtaatga aagaaactgt ttattttgga acttatacac gtcgtacttc
    14641 tcaagggatt tacaaggcag actttgatac agaaactggt cagctttcaa atctagaact
    14701 ttttgcagct gagccaagtc caacctacct tgcctttgac cagcaccaac atttatacac
    14761 tgttggtagc caagacgata aggggggaat tgcagcctat caaactgacg ggactgtgtt
    14821 aaatcatgtt gttgaagaag gagctcccca ctgttatgtt gctgtcgatg aaaagcgtga
    14881 tttggtttac gcagccaact atcacaaggg acaagtcctt gtttataaac gccaggaaga
    14941 tggtagtctt ctacttagtg atatggatca acacagtggc caaggtccac atgaaaatca
    15001 agcttccccc catgttcact atacagattt aacacctgac cactatctag tgacctgcga
    15061 cttgggaact gaccaagtca tcacctatga cctcgatcaa gaaggaaaat tatctaagct
    15121 ctatacctat cacagtaagc caggagcagg ctcacgccat atcattttcc ataaccacta
    15181 taaaatcgct tatctcattt gtgaactcaa tagtactatc gaagttttaa tctacgatgg
    15241 cgttggcgaa tttgtacgta tgcaggttat ttcaacttta ccagaagctt acgaaggctt
    15301 taatggaacc gctgctattc atctctctaa agacggtaaa tacctctacg cttctaaccg
    15361 tggccatgat tctatcgcag tatataccat ccttgcggac ggtagcttag agttattaga
    15421 aatcgttcca acgcatggtc agactccacg tgattttgat ttgacaccca accaaaaatt
    15481 tctcattgtt gtccatcaag actctgacaa tgcaactgtc tttaaacgta attgtgacaa
    15541 tggtcgtcta gcagaactct ccaacgactt ccatgttccc gaagcagtct gcatccgttt
    15601 tgctccttaa aacaccataa aaaatgaact tggtattttc aagttcattt tttcttatag
    15661 tctatttccg acattaatac ggttaatggc acgttgcaaa gcaatcttag cacgacgttc
    15721 ttggtcaatc aaatgtttgt cttgtgcttc ttcaattgca cgttctgcac gaagtttggc
    15781 acgttctgca cgactgatat cgatatcacg agcacgttct gcagagtcag cgacgattgt
    15841 gatcatatca ttggcaattt caataacgcc accgtttact gcaatccagt tcacgtgatc
    15901 tttatcatcg atacgtttta cctttacttc atcaactgct aaaaccgcaa tcatattttc
    15961 atgtcgtggc aagatcccca tctcaccatc cagagttcga accgatacat agctggcatg
    16021 gtgatcatag acgagaccat ctggtgtcac gatctggaca gttaactgag ccataggtca
    16081 cctcttaaaa tcccattttt tcagcttttg caatcacatc ttcgatagaa cctacaccac
    16141 ggaaggcatc ttctggcaag tggtcgtatt taccatcaag gatttcctta aagccacgta
    16201 cagtttcagc aactggaaca taagaacctg gctgaccagt aaattgttcc gcaacgttga
    16261 agttttgtga caagaagaac tggatacgac gggcgcgagc aaccaaggtc ttttcttcat
    16321 cagaaagctc atccatacca aggatagcaa tgatatcttg caattcatgg taacgttgaa
    16381 ggacacgttt tacttcagca gcaactgcat agtgctcttc tccaacgatt tcaggtgcca
    16441 aggcacgtga gcttgaagca agtgggtcaa cggctgggta gatacccaat tgtaccaact
    16501 tacgttccaa gtttgttgtt gaatccaagt gagcgaaggc tgttgctggc gctgggtcag
    16561 tatagtcatc cgctggcaca tagatagcct ggatagaggt tacagaaccc ttcttggttg
    16621 atgtgatacg ttcttgcaat tgacccattt ccgtagcaag tgttggttgg taaccaacgg
    16681 ctgatggcat acgacccaaa agggcagata cttctgaacc agcctgagtg aaacggaaga
    16741 tattatcgat aaagagaagc acgtcttggc cttccacatc acggaagtat tcagcgattg
    16801 tcaaaccagt aagggcaaca cgcatacgtg ctcctggtgg ctcattcatc tgaccaaaga
    16861 ccatggctgt tttctcgata acgcctgatt ctttcatttc ccagtaaagg tcattcccct
    16921 cacgagtacg ttccccaaca ccagtaaata ctgaaatacc accgtgctct tgggcaatgt
    16981 tgtgaatcaa ttcttggatt aagacggttt taccaactcc ggcaccaccg aaaagtccaa
    17041 ctttaccacc tttaaggtaa ggggcaagaa ggtcaataac cttgatccct gtttcaagga
    17101 tttcagaaga ggtagacaac tcatcaaaag ttggagcttt tttatgaatt ggctgacgct
    17161 ctgcgtcttc tgtaaaagga gcttccaaat caatggtatc tcccaaaacg ttgaagacac
    17221 gtcccaaagt ttctttacct actggtacag agattggacg acccgtgtcc aatacttcca
    17281 ttccacgagt caacccatct gttgattcca tggcgatagt acgaaccata ccatctccta
    17341 actccaaggc tacttcaagg acgatttttg tttttctttc gtcatttttg tagacgacaa
    17401 gtgcattgtt aatctcagga agtttttccc ctgctgcaaa caaaacgtct acaacgggac
    17461 cgataacctg agcaatttta cctgaactca tctccttctc ctattctata taagatactg
    17521 tcggttccta gctcaactag gtcctaagtt cattttcata cgagctggac tagagcctat
    17581 tctaaggcac tagcacctgc tacgatttct gtaatttctt gtgtaatcgc cgcctgtctg
    17641 gcacggttat actgaattgt caaatcattg atgactttct tagcattatc tgtcgctgtt
    17701 tgcatggctg tcatacccgc agcattctca gctgtcttgg catcgataat ggcaccgtaa
    17761 atcatacttt ctgcaaactg aggcaacaac tgctccagaa tttcttctcg gctggtttcc
    17821 aattcaaaag tcaagctgta ctcttcatcc gcttcatttg gatccaagtc aacaatcgga
    17881 agcatttgtt ccacacgcat ttgactggtt agcgtattga catggtggtt gtagcaaaca
    17941 taaagctcat caaagagttc attttggtac atttcaacag tttttgaaat aatcttacga
    18001 acttgatcaa agctaggttg gtctgccaag ccacgtaatt cataaagtgg ttgaataccg
    18061 cgagccttaa agaaatcagc tcccatccca ccgatacaga tcatttcaaa acctttaccg
    18121 tctgggtggt attcttcttt caactccata acagctttca aaatagagga attataacct
    18181 ccaaccaaac cgcggtctga agtgataacg atatagcctg tcttcttcac agaacggcta
    18241 atcaacatcg gattagttga agcaccagct ccattaccat gaaggatatc tgtcaaaagt
    18301 ttacgcactt tctgagcgta aacttggaag ttgcgagcag cttcttcaga acgacctagc
    18361 ttagcagccg ataccatttg catggcatta gtgatttgac tcgtattttt tgttgaggcg
    18421 atttttgttt taatatcatt tagagatact gccatctgac acctctattc ttattggaag
    18481 ctagattgat tgagaaactc tgtaatcgca gcatccaaga ctgcttcttc tggcaagtct
    18541 tttgtatcac gaatggtttc caaaatctct ggatgttgag catcaaagaa ggtatggaat
    18601 tcttcctcga aacgaacaat atcatctact ggaacagtat ccaagaaacc atgtgtcaaa
    18661 gcataaagaa tggttacttg tttctcaaca ggtaatggtt tgtgaacagg ttgtttcaag
    18721 acctcaacgg tacgacgtcc acggttcaac ttagcctgtg ttgctgcgtc caagtcagaa
    18781 ccaaacttag taaaggcttc caactcacgg tatgaagcaa ggtcgatacg aagtgtacca
    18841 gcaaccttct tcatggcttt gatttgtgca gaaccaccta cacgagatac agatgaaccc
    18901 gcatcgatgg ctggacgaat acctgcattg aagaggccat cgccaaggaa gatttgtcca
    18961 tcagtgatag aaatcacgtt ggttgcgata taggctgaga tatctcctgc ttgtgtctcg
    19021 ataaatggta gggctgtaat tgatccacca ccaagttcat cagaaacttt agctgagcgc
    19081 tcaagcaaac ggctgtggag atagaaaaca tcccctggga aggcttcacg acctggagga
    19141 cgacgaagca agagcgatag ttcacgataa gctaccgctt gttttgatag atcatcgtat
    19201 acaatcaaaa catgcttacc ttgatacata aattcttccg ccatagcaac cccagtataa
    19261 ggagctagga agagcaatgg agatggttgt gaagcagagg ctgtcacaac gattgtgtag
    19321 tccaaggcac cgtactgacg aagtgtttct acttgcgtac gaactgttga ttctttttgt
    19381 ccaatcgcga cgtagataca gatcatatct tgatcttttt ggttcaagat tgtatcaatc
    19441 gcaatggttg ttttccctgt ctgacggtca ccgataatca actcacgttg accacgacca
    19501 atcggtacaa gggcgtcaat agctttcaaa ccagtttgca atggttctga aacagactta
    19561 cgttgcataa caccaggagc tggtgcttct actggacgag ttttatcagt gtggatttct
    19621 ccaagaccgt caactggacg accaagcgga tccacaacac gaccaatcag actttcacct
    19681 acagggactt ccatgatttt ccctgtacgg cggattgtat cgccttcacg gatatctgta
    19741 aagtcaccta ggatgataat accaacgtct gttgactcca agttttgagc cataccataa
    19801 gagccgtttt caaaattcaa caactctcca ctcatgacat tttcaaggcc atgagcacgc
    19861 gcgataccgt ccccgatata ggttacaaca cctgtttcag tcacatcaaa attgggtttg
    19921 aaattttcaa tttgttgctt aattaaagcg ctgatttctt gtgcgttaat tgccaaaaga
    19981 acaccacttt ctatttcaaa ttttctttaa caactttaag ttgttgttta atactcacat
    20041 caattgtctt gtgattggca aaaatgacaa aaccaccaat gagactttca tcgatttgtt
    20101 cttttacact ccttactttc agagacattt ttttctcaat caaagggagc aaacgagtct
    20161 tctgttcatc agttagagga tgagcagacg taatcgtcac ttcaaatcga tttgtttctt
    20221 tttcaagtcg gttcaagcaa tctacaagca catcataaaa aagatttgct ctgtgattgt
    20281 aggccagaac ctggataaag ttttgtaata aaggcgacac agaatcttgg aaaaaagcaa
    20341 ttgttttttc cttatccgac tcgtctactg ccacttgttt taaaaaagaa ggcagacctg
    20401 ttttttcaac aacttgcttg atttgagtca agtctgaaaa gatacggtct tcttctcctt
    20461 tttcaagtac caattggaca aaaggcatgc tgtatttttc aattaccttt actgttttct
    20521 tgtccattaa gcttctccta gctgatcgat atactgatca atgagtgctt tatgggcatg
    20581 actgtcaagg ttttgtgaga tgattttacc agctaagctg atggtcaaat ctgcgacctc
    20641 acccttaaca ctctgtaaag cttctacttt attttgagca atttcttgat tggctttttc
    20701 ttttaagtgt cctgcttcta gtttagcatc tgctaagata ttagccttac tttgctcagc
    20761 tgtttccttt gcattttcaa tgattgtctt agcttcttta cggctaccag ccaattcatc
    20821 ttcgcgtttt tgagccaata cttctgcttt ttgacgggct tcttcagctc tgtcaatatc
    20881 tgaagcaatt ttttcagctc tttcttcgaa aatgcctgta atattagacc atgcaaattt
    20941 tttaatcaag actagcaaaa gaataaaaga gccagtgatt aaaataaaat taccaattaa
    21001 ttcacctact gttacgtgca tcagttactc ctttctattc ctcttcaata ttaatcttat
    21061 tccctaaata cacagatgtc aaaagagtaa aaacataagc ttggatgcag gaaataaaga
    21121 cagaaaatgc agtccaagcc aaattagctc caaaggctac tggataccaa taaatagctt
    21181 ggtgggaaag aagaagtaac aaactcgtca tgacctctcc tgcaaagata ttcccaaaaa
    21241 tccgcaaagc caaagataag aagtttgtaa attcttccaa gatattcatc ggtatgacaa
    21301 aaacaggact cataaaagat tttatacttt ttttaaatcc acgacgacga acgctttcta
    21361 tatgtgtcaa caaaatgaca agaaaagata aggttaagtc atactgtaaa ttagcggttg
    21421 gcgaactcca ccagttagtc ccatcgatcg tttgaagctt tgtcattaag ccaaggttat
    21481 tggcaatcac catgaaaagg aataaacaaa ggaaaaagag tgagtaatct ttcatgtagc
    21541 gcgaaccaat gttaggttct gtaaatccaa taacaaagtc atagacatac tcaagtacat
    21601 tttgctttcc tttgggtttc aaggtcatat tgcggcttgc ccaataaata aagacaaaaa
    21661 taactcccac aatcaacaaa gtcatggcta acatagtcag attgaagata acaggaccaa
    21721 tagagatgat tggattaata ctttcttcca tctaaaatcc tcccttttct tctcgttcca
    21781 tgtatttatt tgataataaa tgagaagaca agagttacaa agaaagttcc ttcaataaag
    21841 gcaacaccta aaaacatcaa actacgaaac tcagaaagca tatctggttg gcgtgctact
    21901 gatttaaaca gtccattcat caataaacct tcaccgacag atacgcccat acaggcaata
    21961 cataagccta aaaatgttaa attcataaca aattctcctt taaaataaaa tttacttact
    22021 tagtgtagtc ctaaaattta aatttgtcaa cttttaaccg ctattggaag cgtttaataa
    22081 aaattatttc cattt
//
LOCUS       DAVBNZ010000034        21565 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000034 DAVBNZ010000000
VERSION     DAVBNZ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21565
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.034"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            1..1024
                     /locus_tag="VQ860_001353"
                     /pseudo
     CDS             1..1024
                     /locus_tag="VQ860_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ860_001354"
     CDS             complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ860_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET3119778.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ860_001355"
     CDS             complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ860_001355"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET3119779.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(5187..5750)
                     /locus_tag="VQ860_001356"
     CDS             complement(5187..5750)
                     /locus_tag="VQ860_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3119780.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5835..6389)
                     /locus_tag="VQ860_001357"
     CDS             complement(5835..6389)
                     /locus_tag="VQ860_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET3119781.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(6400..7623)
                     /locus_tag="VQ860_001358"
     CDS             complement(6400..7623)
                     /locus_tag="VQ860_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3119782.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(7660..10110)
                     /locus_tag="VQ860_001359"
     CDS             complement(7660..10110)
                     /locus_tag="VQ860_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET3119783.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKMAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQNLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEVKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(10310..11239)
                     /locus_tag="VQ860_001360"
     CDS             complement(10310..11239)
                     /locus_tag="VQ860_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3119784.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            11379..11666
                     /locus_tag="VQ860_001361"
     CDS             11379..11666
                     /locus_tag="VQ860_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET3119785.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ860_001362"
     CDS             complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ860_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET3119786.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ860_001363"
     CDS             complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ860_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET3119787.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13807..16353)
                     /locus_tag="VQ860_001364"
     CDS             complement(13807..16353)
                     /locus_tag="VQ860_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET3119788.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(16476..16916)
                     /locus_tag="VQ860_001365"
     CDS             complement(16476..16916)
                     /locus_tag="VQ860_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET3119789.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16891..17760)
                     /locus_tag="VQ860_001366"
     CDS             complement(16891..17760)
                     /locus_tag="VQ860_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET3119790.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(17738..18238)
                     /locus_tag="VQ860_001367"
     CDS             complement(17738..18238)
                     /locus_tag="VQ860_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3119791.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVFKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(18249..18947)
                     /locus_tag="VQ860_001368"
     CDS             complement(18249..18947)
                     /locus_tag="VQ860_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET3119792.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18940..19176)
                     /locus_tag="VQ860_001369"
     CDS             complement(18940..19176)
                     /locus_tag="VQ860_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET3119793.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19276..20202)
                     /locus_tag="VQ860_001370"
     CDS             complement(19276..20202)
                     /locus_tag="VQ860_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET3119794.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20277..21092)
                     /locus_tag="VQ860_001371"
     CDS             complement(20277..21092)
                     /locus_tag="VQ860_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119795.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVICIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21096..21416)
                     /locus_tag="VQ860_001372"
     CDS             complement(21096..21416)
                     /locus_tag="VQ860_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3119796.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6504 a         4720 c         3807 g         6534 t
ORIGIN      
        1 tcgtcaagaa gaatcaccaa atccctcgta tcatcaacca aaaaattgcg caaaagttaa
       61 ttgaaaagaa ttctatgacc gatattgccc atcagctggc catttcaact tcaactgtca
      121 ttcgaaagct caatgatttt cactttaaac atgatttttc ttgtcttcct gagattatgt
      181 cttgggatga gtatgctttt acaaagggaa agatgagctt cattgcgcaa gattttgaaa
      241 agctcgatat catcactgtt cttgaaggta gaacacaagc tgtcatccga gatcactttc
      301 ttaaatatga tagagccgtc cgatgtcgcg tcaaaatcat tactatggat atgtttagcc
      361 cttactatga cttggctaaa cagcttcgct ttcaaatttc taggctcagg ctgaaacagt
      421 ctcccaggct gtttcactcc cgaatgctaa aatcgttctt gatcgctttc atattgtaca
      481 acatcttagc cgtgctatga gtcgtgtgca tgtccaaatc atgaatcagt ttcatcgaaa
      541 atcccatgaa tacaaggcta tcaagcgcta ctggaaactc attcaacagg atagccgtaa
      601 actgagtgat aagcgatttt atcgtcctac ttttcgtatg cacttaacca ataaagagat
      661 tttaaacaag cttttgagtt attcggaaga cttgaaacac cactatcaac tctatcagct
      721 cttgcttttt catttccaga ataaggaacc agagaaattt ttcggactta ttgaggacaa
      781 tcttaagcag gctcatccta tttttcagac tgtctttaaa accttcctca aagataaaga
      841 aaagattatc aacgcccttc aactacacta ttctaatgcc aaactggaag cgaccaataa
      901 tctcatcaaa cttatcaagc gcaatgcctt tggttttcga aactttgaaa acttcaaaaa
      961 acggattttt atcgctttga atatcaaaaa agaaaggacg aaatttgtcc tttctcaagc
     1021 ttagctgact tcaacccact acagttgaca aagagcccag attaggaact atccgtgagt
     1081 tctctagtct ggagattttt caatagactt cgttattgaa cggttaccaa gttactcaaa
     1141 gtacagattt gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca
     1201 aaaagcaaac taagagcctc aggctgtact tgagtacggt aaggcgacgc tgacgtgatt
     1261 tgaagagatt ttcgaagagt ataaaacact gttttgaggt ggtggataaa tcggctgggc
     1321 aaaaactcaa tctcaggaga aaatgaagta aatctcccca caactataga aaaagatttg
     1381 attctgctcc tcacacaata aaatcttttt cttttattaa aaacgaatcg tttcacgtgt
     1441 tttctcatat gaggtaacaa agcgattggt tacaccaggc tctgccactt ccaatgcttg
     1501 agaaatcttg tcaaatgaag cgtgataatc aaattctttt tcaaaaatat ctaaagcttc
     1561 gttaaatgct tcttgaatgc gttcatcaaa tgagcgatag cggttagaat attgcaagag
     1621 ttgctctgtc aaagttgcat attgtacaat attataagtt tccgtttcta aagcttccat
     1681 atcattcgtt gcaatttcaa gaactcgggt aacagattca atgttaatca ttttttgttc
     1741 taactcaacc attaaatcct cggtattatt gcttgccgta aagaataact tcaagaaagt
     1801 ttgtggaata cctggcagat tgcgtttttc catgtatcgc ttgatagtat ggagacgatt
     1861 gacataaaca ttggcctttt gacgtgcatt aatatcatct ttctcaattt gtgtcaggcg
     1921 ctcactaact gaaatttgct catcttcaat atcttttagt tgagtttgta aatcctcaag
     1981 attttcttca agaactgaat aagcttgggt tggttcttct tgatttgaag ttacctcaac
     2041 aatagctgcc tcaaaactct ctaattctgt ctgaatacga cgaacatggc ttgcagctgt
     2101 ctcaggaagt aaataggtct tgttcaaacg tgcaatatct tctcccaata aagtattatt
     2161 ctctttcata tgttgaaggt aagttggaag agttgcaagt agattttcca ctactttctg
     2221 agcagcaatt tctcgagtaa aaatatcata caaggcattg atttcctctt gtgcctgtcc
     2281 attctcatat tcggcattat ccaattccaa ctgacgaata ttctcttggt ttttcttgaa
     2341 tgcttcataa agcaagtgga aacgcgcttc aatatccgtt tcaacaaaat gataattagc
     2401 atcaattagt ttacgataac cggcttccaa atcctgtaat tgatctggca attctgtaga
     2461 aagcgtagta accaaggctg gaacacgatc cacaatatga cttaaggcca aaatgtgatt
     2521 ttctgtatta tccaaaatca ctgcggcttc cacagggtca cccgatgaat tcaaggttac
     2581 aaattgtgaa aattcagatt ggatattttc taattgtttt tcaatttcat ccaaggcttg
     2641 accatactgt tctgaatttt cagcaactct atgctgaagt tcctcaaata aatccaaagc
     2701 atgaagaaca cgaccactat ttttagattc ttgcttctct aagtctgcca aagcattgcg
     2761 aattgccgca atatcttctt caatcaaagt aatttgactc tcaatttggt caatttgatg
     2821 actggccttg agaaaacgaa atgaatggtt atagccctct gcttcaaaga gattattttc
     2881 aatatcggca aaagagttga gagataaatc gacccatttt tgattccatt cacggaaagc
     2941 cacttgactt tgtccaatca agtgcatatt ttttacagct tctacttcat catttactgg
     3001 aagattgtat agttcttctt ttctttcttc tagtgcctct aatctcccct cgtttcgctt
     3061 acgtagaaag attgccacta cataagccag aactaaaatg actgcaattg caaccattaa
     3121 ataaattagt tgtccattag acatatcaaa ctcctttttt acttgaaaca atcgtaacga
     3181 ttatatcata ttttttagac caagggaact acttctccct attttttaga catcaagtgt
     3241 actatagaca gcattttctt cgataaactc acgacgaggc tctactcgat cccccatcaa
     3301 catatcaaag attttatctg cttctgcagc atcatctaca gaaactctag ccatcaagcg
     3361 atgttcggga tccatggttg tttcccacag ctgatgatcg tccatttcac ctagcccctt
     3421 ataacgctga atagtcggtt tggtacgacc ttcactataa cgggctaaag cttcttggag
     3481 tttgatttct tgatctgcac ccggctggat atattcttta atctcgcttc caaccttgac
     3541 accatagatt ggtggttggg caatataaac ataaccagct tctaggattg gtttcatata
     3601 acgataaatc aaggttaaaa gaagggtacg aatatgggct ccatcgacat cggcatcggt
     3661 catcaaaacg agtttttggt aacgggcttt cgaaacatca aattctgcgc caaatcctgt
     3721 tcccatggct gtgaaaagac tacgaatttc ttcgttagct agaatcttat ccatacttgc
     3781 tttttcaacg ttcaaaatct taccgcgaat tggaaggata gcctgaaact cacggttacg
     3841 accagatttg gctgatccac cagctgagtc tccttcgacg atgaagagtt ctgtttcagc
     3901 agggttatta gaagaacagt ctgctagttt ccctggaagg ttggaaattt ccaaaccaga
     3961 ttttttacgt gtgacttcac gcgcacgctt ggcagccaca cgagccttgg cagccaaaat
     4021 tcctttttct acgatacgtt tggcaatctg tggattttcc atgaggaaat cggagaaggc
     4081 ttcactgaag aggcgattgg taatcttgac cacttcgcta tttcccaatt tggtcttggt
     4141 ttgtccttca aactgtggat ttgggtgttt aactgagata actgcagtta atccttcgcg
     4201 aacatcttcc cctgttaaat tatcttcatt gtctttcagt aacttattct tacgagcata
     4261 atcattgata acacgagtca gtgccgtacg gaaaccttgt tcatgcgttc caccttcatg
     4321 ggtatgaata ttattggcga aactcatgac attttcatgg taacctgttg tgtactgcat
     4381 ggctacctca actgtgatat catccatctc accgtctgta tagattggtg tatcaaagat
     4441 tacatccttg ttctcgttga tatattcaac gtaactagca atcccacctt cataatgata
     4501 atgcttggtt tgttccaaac cttggcgctt atctgtaatt gaaatttgaa gaccgcgatt
     4561 tagaaaggcc aactcttgaa tccgtttatt taatttatca aaatcaaaga ttgttgtttc
     4621 agtgaagatt tttgggtccg gtgtgaagtg aacagttgtt cctgttttat ccgtatctcc
     4681 aactatttca agatctgcga caacatgacc acgacggtat tcttggtaat gaatcttacc
     4741 atttttgtga acatgaacgt ctaattgagt ggaaagggca ttaactactg acgaccccac
     4801 cccgtgaaga ccacctgaaa ccttgtatcc accaccgccg aactttcctc cagcgtgaag
     4861 gactgtaaag acggtctcaa cagcaggacg gcctgttttt tcctgaatat cgactgggat
     4921 accacgccca tcatccacaa cagtaatcga atcatctggc tcaataaaaa cttgaatatg
     4981 gctggcaaat cctgccaagg cctcgtcaat tgagttatca acaatttccc agactagatg
     5041 gtgaagacct tcttttgagg ttgatccaat gtacatccct ggacgcatac gaacagcctc
     5101 taagccctct aaaacttgaa tttgactggc atcataatcc tgtgcctgca gatttttgat
     5161 ttcttctgtc atcttattcc tttttcttat atgtctaata cttgtcttaa attcacgata
     5221 ctggtaaaca agtgggtatc aagtcctgca gcttgacctg cttcgatatc aatcggccga
     5281 tcaccaatga caagaccaga gctaatctga tacttttctc ttaaataaag catggattcg
     5341 ggatttggct ttctcttaaa gcctgagcta gaagtcacca cttctgtaaa ataagctgct
     5401 atagaggttt tttctaaaat ttccaaaacc tgatcatttc gatgagagac caaaaaatga
     5461 cggccacctt gatttgaaat gacttccaat aggtcagaaa ctccttcaaa taaaatcggg
     5521 tgttcaagct ctctggcttc attttccttg tacttttcta aaaaattctc taaattggga
     5581 gcgaatgtct caatcgcaaa aggagtagaa acctttaaag cttgatagac actgtcatgg
     5641 tcttgtgtga taccatacag tgccaatgtt tcaacaaatg cagctgttga agtttcataa
     5701 ttatccagta aagttccacc taaatcccag atgtaatcgt gatatttcat atccttcatt
     5761 atagcatttt tttatgaaaa aagcgatgat ttccctgagt tttccacata aaaaacgaga
     5821 gaataactcc cgttttactg atttttacca aagacatctt gatagagcat tcctgttcgt
     5881 aaactctctg cgtcccctcc tagttgctcc accaactcgt aggcaaaggc aagggctgtt
     5941 gaaggacccc gactggttgt caactgacca tctaccacta ctgtttcctt gacgtagtga
     6001 ccatcaagga tttgctcttg aacgccgtca taacaagtgt atcgcttatt tttcaatatc
     6061 tctgcttgat tgagggcaat tggtgccgca caaatggctg ctagtttctt cccttcttgc
     6121 tcgaagcttt gcaattcttg aatcaaggtc tgattatcac gtaaatgtgc agaaccaggc
     6181 atacctccag gaagaacaat catatcatag tctgataaat ctccatcaaa gacatgatct
     6241 gctcttactt ggattgcatg cgaacccgtt acttgctctt caaaaccaac catatcacat
     6301 gtgatattgg ctcgacgcaa gacatctaca actgtcaagg cttcaatttc ttcaaagccc
     6361 tgagctaaca taactgctac ttttaccatg attttctcct tatttaattt gttttaatac
     6421 aacctttttc cgtttgaatg ggacttttcc gctcttttct tcagctagat tagtctggta
     6481 actcatcgat aaaagcaaac caacaccaat cagattactg ataatagctg atcccccttg
     6541 cgaaataaaa ggcaagggaa tccccgtcaa aggaagtagt ccagtcacag caccgatatt
     6601 ctcaaagatg tggaagagca acatcataat caaacctgtg gaaatataag tgtagaactg
     6661 gttatttgat ttaagagtaa tcttcaacat acggtaaatc aacatgagat agagggcaat
     6721 aaccaggaca gagccaataa agccaaaatc ttctgcaata accgtaaaaa tcatatctga
     6781 ctctcgaact gggataagca gattcgaagc attaaatccc tgaccaaata agccaccact
     6841 cccaatggca atctgtcctt gagcctgctg gtaagtcgtt gtttgggcaa actcaaaggg
     6901 attgagccaa gccaaaatcc gattaatttg gtaggtcggc attccaatct ggtgaagaaa
     6961 agctcgtccg tccttgctaa taaagatagc taagaaacca gcaactcctg ttacagcagt
     7021 cacaaatact gggataataa ttttccaaga aacccctgat aataaaacga ttcctgagaa
     7081 aatggctaca aaaaccaaag ccgtccccaa gtcactttga agtgctaaaa gaactaggac
     7141 tggaatggta aagagaatca tccagaaaat taacaaaaag tccagcggaa ccgtgcgtct
     7201 ccattcctta tgtttctttg taaattggac aatgacacga gccaacatga ggatatagga
     7261 tatcttcata aattctgacg gttggaatag ggtaattcca tttattgata cccagttttt
     7321 ggcacccgtt gatgcaacta agcttggatt ataaaataca atcggcaaga tcataagtcc
     7381 caagcctaaa atatatagaa agggggtcac cttccaaaga aattctgtat taaagagcat
     7441 gaccacaaaa ccaatcacaa gccccaaggc aatccaggcg acctgctgcc ctaaaatggg
     7501 cagaatatta ttgggataat catgactaac ggctatatag atagccacca caccgatgac
     7561 cagtagaaaa aatactggca agagcaaact gtaatcgact cttgagtcga gagaacgttt
     7621 catatatact aaccttatac tttcatacaa tactatttat caaagttcat taaaaaatct
     7681 atcaatagcc tcgtcaactt cggatcgaga gatggtttta acagtcgctt cttctgctag
     7741 agatgctact atttgtttgc cgtatcgttt tccgacgatt ctcctatcca aaataagagt
     7801 taaggaacgt tggtattcac gtctcatact tcttcccaaa gcctgtttta aacgaataat
     7861 ggccattggc aattgataat cataaaaggc atttttccct tcttgattca gttcttgatt
     7921 aatctttttc gtcaagggtt cttgaggatt ttggaaagga agcctcggta caacttgaat
     7981 cacaaaagga tggcttgaaa aatcaactcc ctcccagaaa cttgctgcac caagcaagat
     8041 ttgttgttca cctttttcaa agcgtttctt tagctgatga acatccccat ttttatactg
     8101 ggccaagtgg ctaactgtaa gtaaatccga tactgctaga agcatgtctt tagcggtaaa
     8161 gagaaccaaa atcggttgct ggaaagcttg aatttccact agtaaagcag ctacctctct
     8221 ggcatagact tctaaggagg tttctgttac cagagggaaa tctttgacca taaccacttc
     8281 ttgttcctgt tttccccgag attcaatctt gacaaatttg acttcaggat agcctaaaag
     8341 gtctgccaaa gaaaccctct gactaatctc aagagtagct gatactccca agacttggca
     8401 actctcagga agtaaagagg acagaagagt acggcctgat tttgtagaag aaatctgaat
     8461 tttcttttga ctcgtttcag ttacttcaag ccagtaatca ccttcagctg taaaatagcg
     8521 aaccagctca tcaaagcctt ctacttctaa ttctgaaaaa tactgatgga gattgtccag
     8581 agaatctaag atatttttcc tagatttacc agactgaaat tgttctatca agtagagaca
     8641 ctcaaagcga atactttcta gtatccgttg ttgaaccctg ttttcttctc ctactaaagc
     8701 cttatcaatt aaatcgataa tagattgtat atcgtaggtc tcttgaagca gattttctag
     8761 agctaacaaa atcttttgga cttcatcaat aatcagtaaa cggtcactga caaattcagg
     8821 attatcttca agtctggtta cgagataggc atgattagtc actaaaagct tgcaagtctc
     8881 tgccctttct tgactacgtt tccaaaaatc ttccgtcaca aataagttct gggatgataa
     8941 attcccatca tgacgaaggt ctgctagaaa atgttggtaa cggtagagtt gcccgatttc
     9001 atccaaatct cctgtctctg tctcagtaag ccagaccaag acttgcattt taaagcgtct
     9061 aaataagcga ttttcatcat tttcctgcaa ggaatgataa aaggcatcca acttcagata
     9121 attttgtggt ccctttaagc tatgaatatc tgtatggaac acttccttga ggcgtttacc
     9181 ttcttcttcc atgatttgat tttgaagaat ctttgtcgga acactaagaa caatttgtcg
     9241 ctctttggat tgagataaag cgggtaagag atagccatag gttttcccaa tccctgtcgg
     9301 cgcttgaatc agagagacag gttcatcttt caatagcaag ccaacctctt tagcaaaact
     9361 ttcttgttcc tccctcactt caaggttcaa cagagaaata tttttagaaa agtcttgaga
     9421 tagttttcgt ggctccagag aagctgccat tttcttaaaa tacagacctt gaacttggac
     9481 caagtctgga gaactcagga tagattggtt gcgataagtt tcctcaataa ccaggtagga
     9541 ctcatatagg agagcgtcag ccatttccag caagcgttcc aagagacctt taggaagctg
     9601 ggtcatcttt tcccgtaaaa aaagaagtaa ttctgctgta gcttgggcat ctgaaagggc
     9661 tgtgtgtgcg tgtttaagag gaattcctaa ttctcgacac aaaatcggca agctatattt
     9721 ttccagttca gggaaaaaga cctgggccaa ttcgaccgta tcaacacgag ggtttcttag
     9781 ctcatagcct tcaaaaaata aattttccgc caagagatta gcatcaaact gaacattatg
     9841 ggctacaaaa atcccatcct ccaccaagtc aaatattttt ctggcaactt gcgaaaaatc
     9901 aggtgcttgc gccagacgtt ggtctgtcaa tcctgtcagt tctttgatat gagcatccaa
     9961 gggttcatgt ggattgacat ccgtcgtata gtgatcgacg atttctccat cctcaatcac
    10021 gacaattccc acttggataa ttttagcctt actacctgtg ctagttgcct ctaaatccac
    10081 cacaacatag cgattaccaa tcgttttcat tataaaaaat tataccaaaa aaagggccat
    10141 ttggcaccta caaacatagg ataattttca aactcaagaa cactactttt cttaaaaatc
    10201 ccatcgaata gagcattcta gcctgctgat ttttgtaaaa tagtgaagaa atacgaaaaa
    10261 ttgagagaag aaatgtttgc atcttccttc tctcaacgaa tcatgtattt tatttaacca
    10321 tgtcaggatc gtagtcataa aatcctgtat caaggaaacg gtttttaggg tgaagtttac
    10381 gaacttcttc atccagcaag aaggcttgat catggctaaa gttgccctct tgaatcaagt
    10441 tacgcgcttg gataaagagt tttgcaatct caacaaagtt ctgaccagga gtgtagagcc
    10501 cttctagttt ccagcgagta aagccatgct ccaccaattc tgttaatttg atcatcaaat
    10561 caaggtcatt gttggcaaag atatgggtcc catgattatc ttcaaaaatg gaatagtggc
    10621 tctctggatc acttggctca gccaagaaga ggtcacgttt atgcgtcttt tcatcatcga
    10681 tatgtgtaaa gttatagtag ttttgcaaga gtggacgttt agaatgatgg atgacgctag
    10741 caccgtaaac caaaacttca gcaggaattt ccaaaatctc tggcattttg aaaagttcag
    10801 ctgatggaat ttcacgcgcc aaaacagcct cagatgcgcc agccttttgt ccccagaagt
    10861 taatctgacg actgctagtt accatggttg aagcatcgta gatggtctta aatgaataac
    10921 catcgcggtt aactacgtaa aagacgcctg catccccaat cgtaatatag tctgtcttga
    10981 tttcttccaa gaagtctaag aaaggcttga tacggtccat catatcttgg tgcatgagag
    11041 cattgaccgc aacgatcaat tccttaccag catcatgaac caacttagcg atttcacgta
    11101 attggtcata actaaaggtc gttggcagac gaaggccaaa atctttctca ccgacataga
    11161 tacggtctac gccagcttcg agtagttgtt caacttgttc aatactttca gcagttgctg
    11221 taatgacaat cttttccata agaaaaatta taccacattt ctccaaaatc atccatgctt
    11281 tgaaaatgaa aagggacttt attctttttg taacctttct gtaataattc tctgccgaaa
    11341 aaatgataaa ataggtatgt actgttaagg agagaattat gcccgtaaga aaattacaat
    11401 cctatgaggt agactatcaa gaagaattaa accagcagct tcctcattac caagcttata
    11461 cacctgaagc gcaatctgat gccaatctca aggaaatcct attttttatt aatatcgctg
    11521 ttttttgtat ctgtattgct atctttagtt ttatcttttt agcattaaaa ttatcaactg
    11581 ctcttgcctt tgccgcagca atcggattca gcttacttgt tttaaaagtt caacggtcta
    11641 ttatcaaacg aaaacgtaga agataaatcc aaaatatcgc cccagttgga gcgatatttt
    11701 tattttttct ttttagatgg tgtctgaatg gcaatcttca cttcaaagat tgttcccttg
    11761 ggtttattat ctttgacagt aacagttcct tttagagcat ctacaatttg cttggctagg
    11821 gataatccta aaccaaaacc acctttttgc cgggttctag ccttgtctac tcgataaaaa
    11881 cggtcaaaaa ttttcttttt atcttctgtc gaaataccga ttccattatc agaaacaagt
    11941 aaataaagat tgcgatcggt cgccgagata agaaaatcaa tttcaccatc ctcctcagta
    12001 tacttgacgg cattatcgaa aagaatggtc atcagttgtt tcagaagaag ctgatctgtg
    12061 acaattgttc gatggatacg attttcaaaa cggaagacac gattattttc cgaagcaatc
    12121 atctcatagt ttgtgaaagt tgtattaaaa aagctagttg gaacttctgc aagctctggc
    12181 ttaatcccat catctctccg agctaagttc agcaagcttg tcgttaaaaa acgcatattt
    12241 cggacttctt ccaaactcga tgcaatgctt tcactcacat ccataatggt agcttctggc
    12301 ttacgaaaaa gggtctctaa gcgattttgc aaaactgcga gtggagttcg taactcatga
    12361 ctggcatttt ccacaaaaga ctgttgcttc tgcatactct caagcagggg cctaacactg
    12421 accctagcta gatagagact ggcaagtaaa gacaaaatcc agaaactagc catcacgacc
    12481 acaatcaatt gctcatgctt ttgactagcc tgctccaact gactggtatt aatcaagaca
    12541 gcagcatact tgatattggt tgaaaccgaa ctaatattgg tctccatcaa aatcacacga
    12601 tagatttctt cctgcccata gctattaaaa acctgaatct ggtagatatg tcctagttct
    12661 ttcttttcta acttaatctt atccaagccc aaaaatcgat ttccagaaag aagttgagta
    12721 aagtccttat caaagagaat gacttccgta ttggaactga cattaggttt tatttctact
    12781 ttactagcgt ccgccctagc attttctaaa tctttaatct cttctgttgc cctatttata
    12841 gccagctgaa taactgcttg aggattttca ctcagtccat gaagcttatc gtccaccgaa
    12901 gtataaagac tcgaatgcat gacttgtaaa ataatcagag tcattgtaga aaaaatcagg
    12961 gtgaagacac cgaagttgcg gataaaataa ctaaagtcat ccgcatacca tgttttttta
    13021 agtttactga acatctttta aaagataccc aacactacgc aaggtttgca aattctctgc
    13081 aaaagtggtt ccctttaatt tcttacggac ttttgaaaca tagacttcga caaccgaaat
    13141 cgttgtatca ctatcaaatc cccatagacg gtcaaaaatc tgcgtcttag gcaaaatcac
    13201 attttgattt tgaaggaaat aaactagtaa atcgaactct ttccccagca attcgacagg
    13261 agtatcttca actttaacgg tattggttga taaattaacc acgatattcc cataagtcaa
    13321 ggtgttttca ttaaacttcc ctgaacgttt gagaagggcc tgaatccgca ttttaagttc
    13381 ttctaggtag aaaggtttgg tcagataatc atccgctccc agttcaaatc catgtccctt
    13441 gtcatccaaa ctttccttgg cagtcataat cagaactggt gtcgtaattc ccttttcacg
    13501 caattctttt aagacttgga aaccattttt ttctggcaac atcaaatcca gcaaaatcaa
    13561 gtcatagaca ccactctcag cttcgtagag accttcttct ccatcaaata cctgcataac
    13621 atccgcaaaa tcgtctaaaa agtcaaatac tgaatttgac agacctaggt catcctcaac
    13681 caataagatt tttatcatga gaaactcctc cttattaaaa ctattatacc aaatttgcct
    13741 taaaaaaaac tcaactctct gcattttaca tgagatagct gagttttctt tttattttag
    13801 gcttatttat gcatttccgt attgaagaac aactgcttcg actgcagctt tttcacggct
    13861 aatcaagtca acacgtgctg caatttcctt gattcccata ccgatgttac ggctaagagc
    13921 aaggtcagaa agttgcggct caaagaactc cttgtattcc gccaagcgtt gctgagtctt
    13981 aaatacatga gcaggaagga taacaaagct atcaaagctc atatctcctc caagggctgc
    14041 cttaatccaa gcccagtttt cacgcgccca agaccaagct gttttctgag ttgcttgatg
    14101 agctaggaat tggtaatacc aagcagacaa gtcctgtggt ttgaccacaa atttgtcctt
    14161 ccaagaagta atcaagtttt ggatattatc cgcatctgta ctgtatgcaa gagctgctgc
    14221 caactggcgt ttaaagacag catctgttgc gtgagtataa gtatcaagat aaagtgctaa
    14281 caagtcttta gtctcatgat gtttcatctc attaatcaga acttgtgaac gaatagctgc
    14341 tgggagtcct gcaagattct ccttgtgtgt tgcgaagatt tggctagcga cttgactagc
    14401 ttctgcatca tttgagcgaa tcatcatcga aacagccagc tgacgaacca attcatcctc
    14461 atctgattct ccgtctttag cttcaaaacc aagacggtca tagttatgac gagccaattt
    14521 agcaaccagt cctttgaagg ctgtttcagc atccgttcct tcatcaataa agcgctcaag
    14581 agctgaaatc acttgagaaa cagctgaaac caccagataa gactcttcct tagcaagttt
    14641 atcaagaact ggaagcaagt ctgcataaga aatgtgccct gcctcagcca acaaacgacg
    14701 ttcttgaaca atttgcagtt tgcttgtgtt atcaagtgtc tctagctcag caagaacagc
    14761 ttctaacaag tctccttgat agtcggtaat atagtgggca gtattttcag tgttgagacg
    14821 aagagctcct tcattttcag caagaagagc tgcgtagcca gggatttcga tactttcagt
    14881 ttcgagtgta tcaggcaagc ctttccagtt gctattgagg ggcaccaccc agagacggtt
    14941 cttgtcttcg ttctcaccga tgaagaattg tttttgtgaa atcttcaaga catcattttc
    15001 aactttgaca gtaagaactg ggtaaccagg ctgttccaac caagaatcca tgaaggctgc
    15061 gacatcacgt cctgacgctt gaccaagggc atcccaaagg tcactaccaa tggtgttgct
    15121 gtattggtgt ttttcaaagt aggcgtgcaa acctttagca aaatcagcat ctcctagcca
    15181 acggcgaagc atgtgcatga gacggcttcc tttggcatag acgatagcgc cgtcaaagag
    15241 tgtattgatt tcatctggat gtttaacttc gacgtggaca gactgaacgc catcagtagc
    15301 gtcacgttca agagcaagag gtactccacc tgtttggaaa tcttcaaaga tattccagct
    15361 tggttcgatg gtatccacac agacgtattc catcatatta gcgaaacttt cattgagcca
    15421 aaggtcatcc caccatttca tagtcacgag gttcccaaac cattggtgag ccaattcatg
    15481 agccacaaca agggcaactt gttgacggct agcaaatgta gagttttcat cgacaaccaa
    15541 gtaaacttca cggtaggtca caagacccca gttttccata gcaccagctg agaagtcagg
    15601 aagggcgatg tggagagatt gaggaattgg gtacttaact ccatagtaat cttcgtaaaa
    15661 ctcgatagag cgaacagcga tatccagtga gaaatcaaga tttgaaagtg gatgtgcttt
    15721 ggttgagtag acacctacca gggtaccatt tttagtttta gcggtcaccc cttgcaaatc
    15781 accagcaaca aaggccaaca agtaagaaga catgcgaggt gttgtctcaa acttccagat
    15841 acctgtttcc ttacggtttt caacatcgat ttctggcatg tttgacaagg ccaattcacc
    15901 ttctgcttgg tcaaagcgaa gagagaggtc aaaagttgct ttggcttcag gctcatccac
    15961 acatgggaaa gcttcgcgcg caaaatggct ctcgaactga gtagacaaga cctccttctt
    16021 gactccatca actgtataat aagaagggta aatccctgtc atgttgtctg taattttacc
    16081 agaaaaggca agaaccaatt caacttgacc agcctcagcc aattcgatat gaagggcttc
    16141 attgtcatgg tcaactgtaa atggacgagc ttgacctgca acttctacag aggtgatttc
    16201 caagtctttt tggtggaggg agatgcggtc actctgtgct tgaccagtga tggtcacttt
    16261 cccagaaaaa gtcttggtct cacgactcaa atctaaaaat aaatcataat gttcaggaac
    16321 aaattgctta ataaaatgtt caactgcttg catagttttc tcctattcta agtttaagag
    16381 ctgctgctct tcttcaaaca aacttattat atcatatttt gcttgagaaa aaaggattgg
    16441 acagcgattt ccaaaacttt cttccttcta atagtctaca gtgggtagac cttgcgaaat
    16501 tcttctaaaa caaccttgct ttcaggtgta aaagtcagcc ctacttcacc caaacagtct
    16561 gtgaaaaagt cctcatgaac ctggcgccaa taggcaagtg atttgtctcc ctcaccttcc
    16621 ttaaaggcat gttgcgcaga aacttgattg aagagttcaa cagaaacctt tgtaatttcg
    16681 acaatgcaga cagcctgatt ttgactatct aaaatgacat cgaaggtccc tacttgggga
    16741 agtggttcgt cttctagtac atagaggtca taggctgatg ctgttgctgt cttttctcct
    16801 ttaaacacca aatccgctaa aaggtctggt tcaactccaa aagcccaagc atcgatttca
    16861 tctccgatca aaggattgat ttgcttgtat ttattccaca tttcttgcgg tgtcatgggt
    16921 actcctttgt aattttttac tttcttcttt tatgtgttta agatgatctg gatggtcaat
    16981 ctctaaatca aaaatctctg gaatagaact gtagtggata atgcacttga tacccaactg
    17041 attcattttt tgtatgaaag aagtattcag atagcctgct acagcaaaat taatcttgtt
    17101 ctttcttgct ttatcctgca tatctcttag catatctaac attattggac tttccatatc
    17161 atgccattga ctgtttctca tagtcgcaaa aacaaaggaa gtcaaatcat tcattccaac
    17221 tacaatcttt gaaatgcccg tttccagtat actagataag tcaaaatacg ctgacggtaa
    17281 ttcaatcatc gttccgactt tcccagtaaa gccatactga cgcaatactg taatagcttg
    17341 ttttaattgg tcggcatcat tgacaaaagg aaagataaca gatagattgg ggttggtttg
    17401 ataaacttct gtaacgacat gtgcttcagc ctgaaattca tccaaacacg ccagtaaacg
    17461 cctagttcct ctatagccaa acaagggatg cccttcgtca aaaaactctt tagtccccac
    17521 taaacaattg gcttctgtat tcgttaattc agtaaaacga taccaaactt cttcatctga
    17581 gtacagggag cagatagtct ctagataatc ttttacaaat tgctgacaac ttgctaatat
    17641 gatgttttga ttaagctctc tcaacaaata ttccccacga atcatgccga cgtggtgaaa
    17701 tagttgagga taaatttttt caagaatttt ttcgccacta agggcaagtt gatttctcat
    17761 cattcacctt ccaattcatg taagaagtct tgtccagttc tggaaatcct aataattcag
    17821 acttaacctt aaagactaat ggcgatgcat tttcttctgt aatctcttga atatccatcc
    17881 aaatatatcc aagtgaatca ttcgcaccat cagacacagc ttccgaaatc gtaacttgag
    17941 gtgcactctc attcatttca acatcataca aggccatgac atggtgaacc ataaaatttt
    18001 ttaactcttc tctgacgaaa acatcgtaga ttcgaggatt agagtagctt ctaacagtaa
    18061 atcccgtctc ttccataact tctctagtca gcgtttccgt cagtccttca ccaagttgct
    18121 gactgcctcc aggtagatca taccgatgtt gataagggcc tctcgttttt tcaatgcaga
    18181 gtaacttccc attttctaag caaacagcgt agactccaaa gtgttttttg atttccatcc
    18241 aactcctcct acttcaaaga ccagccacca tctattgtca agatttgtcc ttgcatggcg
    18301 ctcgcttttc cacttgctaa aaaaagacta agctctgcta tttcctctgg ctcaatccag
    18361 cgcttgattg gggtttcact agccacccag tcagccaaac cacctggttc aaaatccgca
    18421 gcggtcatag ctgtcttgac tgctcctgga gcgataccaa agacctgaat cccagcttca
    18481 gcatagtcta gagccaactg cttggtgaag ccagccaagg catgcttgga tgaagtatag
    18541 gcgtgaccac ctccacctgc taggctagaa gcaatggaac acatattgat gatgattccc
    18601 tttttatttt ccagcatttg tgtcaaataa taccgagtca actctactgg aataatgtag
    18661 ttgatttcaa aaatctcttg aatgtcctgc gccgtttgtt ccaacagtgg tttgtaatca
    18721 tccaaaactc cggcagtatt acacaaaaca tccacctgag ggcaccagtc aaaaataggt
    18781 tccaagtcca aggtcaaatc tctctgtaaa aagtgaaaat caccctctaa gagtggcttt
    18841 tcaccttggt caactccata aacttgatag cccttctcta aaaagaggcg agcttgagcc
    18901 aatccgatcc ctgaactcac tcctgtaatg agtacacgtt tagtcatgca cttctaccca
    18961 atccgttgcc aaaacatcac aagctgtcgg gctccacatg gaaaaacctt ctccttctcc
    19021 agacacgttg attaagaaat aaggtgtcac ttcaagtgca agcccatttt gctcgatggt
    19081 atcaaagagt tggacatagt tttcagcacc tccccaacca gttcgtacat attttttctt
    19141 agcctttaag ccaggtagaa tttcttcaaa tgtcatgttt ttctccttta atgtcaataa
    19201 ttctcccctt cattataaca aaaaaaccgc tttaaaacgg ctttttgact gtgatttatt
    19261 tacatcttct tctacttacg gcaaattatt ccctgcagca agataaattt cataccattc
    19321 ttttcttgtt aagctaaagt ttgccgcttg gctaacttct ctcaagtgct taggatttgt
    19381 ggtacctaca actgcctgca tttttgctgg ataacgcaat atccaagaaa tggcaatagt
    19441 tgaagaggtt actccatatt taatagctaa acgatcaagt acttgattta aagcttgaaa
    19501 tttctcattt ccaacaaaat tccctttaaa atacccgaat tgtaagacag accatgcttg
    19561 aatgaccaca tcgtgtaatt ggcaatattc aaaaatgctg ccatctcgca tagctgcttg
    19621 actatcttcc atattaacat gaaaagctga ttcaaatcct ggagtaaaag ccgcactcaa
    19681 ttgtagctga ttaacagcta acggctgctt gacatctttt ttaagcaact ccatcatcat
    19741 aggattttga ttagaaactc caaaatctcg aactttacct tgtttataaa ggagatcaaa
    19801 ggcttctgct acttggtcag attccatcaa agcatctggt cgatgaagga gcaagctatc
    19861 tagatgatca atcttcaatc tttgcaaaat accgtctact gattttataa tatagtcctt
    19921 agaaaaatca aaataggtaa attcttcaat gcgaatgcca catttggact gaatccacat
    19981 cttttctctt aaatctggac gattttttag gacaagacct aacagttctt cacaacgacc
    20041 acgaccataa atatcagcca agtcgaaggc attgattcca acagaaagtg ctgtttctac
    20101 aagctcttca acttctttta cagacttatc ttttattctc atcattccga gaacaatttc
    20161 tgataattct ttgtcatctt gaccaagagt tatgtatctc atcaaatttt tctcctttaa
    20221 tttctaacat tcttcccttc attataacaa aaaaccgctt tgcaacggct ttttgactat
    20281 acttcactcc attttatctt cttaaaccca cggaacaaga caaagattcc aataaagagg
    20341 acagctaaag gaataacttt tgtaaggaaa acatttgaaa ttcccatcca ctcataataa
    20401 cggagcagag aacccaccac aagatgggca ataatcatac tgacaaatgg acgaaagacc
    20461 gcttctttcc aattccaaat acagataact agcgaaatcg taaagacaga caaactatcc
    20521 cagggagccg gaatataaaa ggctccttct tgtatgaagc ttgccattcc tacatatcct
    20581 aaaacaacta aaagaactat agtcccaaca acaatgtaag tgccaatttt cattttagga
    20641 gaatcttgga ctaaacttct tcgtaaaatt gtggccacaa gtccaaatcc aatcagaaaa
    20701 ataagaagtt gccctaaaaa tgtgagcaaa ttgactgtta agagaggacc tttagaaaaa
    20761 tcacttagta gttgataata acgtaatacc gccaggacaa gaattggcgt caaaagggac
    20821 tctttgatag aactgcgagg tgctcccttg agaatctctt tcattatttt tttaggattc
    20881 ttacctagat aatcctctgc actcatgcca tctcgttctg cttctgagaa atctagcatc
    20941 atcaaataga tctgctctct gagatagtct tcatcataga gaaatccagc aagattaaaa
    21001 ctttcccaca actcctcaaa atacttttga ttctcctcag aaaactcatg tagcaaagcg
    21061 cttgtttctt cgtaatactt cattttcttc atggtttaac ccccattctt aatcccttct
    21121 actttttgac tcaaatcgtc ccattgttgc caaaagactg agacacgctc ttctccttct
    21181 ttcattaatg aaaaatactt ccgatctgga ccatctggcg acgggcgcat gtcgcctctt
    21241 atccattgat ttttttctaa cttttgcaac aaaggataaa tagttcctgg aacgatagta
    21301 tcaaatccag cctctcgcaa agtctgaacc aactcataac cataccgctc tttttgacca
    21361 atcatatcca agacacaacc ttcaagaaca ccttttaata gctgagtttc tttcatcact
    21421 tctcccttct aatctatttt gtaataccta ctagtaactt cacctatagt atatcacttc
    21481 tacactagtt tgtaaagcat aatagttaat actcttcgaa aatctcttca aaccacgtca
    21541 gcgtcgccct accgtatgta tggtt
//
LOCUS       DAVBNZ010000035        20762 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000035 DAVBNZ010000000
VERSION     DAVBNZ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20762
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.035"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..195
                     /locus_tag="VQ860_001373"
     CDS             <1..195
                     /locus_tag="VQ860_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119797.1"
                     /translation="KKDYIEFKRVGIVDGKAVEVTLREPYSRDLLKVVKSIKQRQKLI
                     AYRYKEGKLLFVKKEASDVL"
     gene            185..673
                     /locus_tag="VQ860_001374"
     CDS             185..673
                     /locus_tag="VQ860_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119798.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYAIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     AKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            673..2550
                     /locus_tag="VQ860_001375"
     CDS             673..2550
                     /locus_tag="VQ860_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET3119799.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGKEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQESDERWWNYQINPLNQRQENYLDDLRIRDLTFESSL
                     K"
     gene            2571..2813
                     /locus_tag="VQ860_001376"
     CDS             2571..2813
                     /locus_tag="VQ860_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119800.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            2830..3684
                     /locus_tag="VQ860_001377"
     CDS             2830..3684
                     /locus_tag="VQ860_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET3119801.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTLSGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            3738..4097
                     /locus_tag="VQ860_001378"
     CDS             3738..4097
                     /locus_tag="VQ860_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET3119802.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            4048..6405
                     /locus_tag="VQ860_001379"
     CDS             4048..6405
                     /locus_tag="VQ860_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3119803.1"
                     /translation="MKRKSNTLKKQKTSMTNKKEEVKGKKEEVLPSTANTLSYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDTYRKELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGEDRVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGIFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNVAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRAFGGEMIDIAP
                     DSQTYLNVLDLSDENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            6417..9230
                     /locus_tag="VQ860_001380"
     CDS             6417..9230
                     /locus_tag="VQ860_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3119804.1"
                     /translation="MKDKRKIIRARKAFRRSLKDEKKFLKKGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKEGRKERKTNQKFLYGQESKAKSNFFFQGKSLEELKAKKE
                     VKDAKENLKSTKQAYKSKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     YRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELHKPV
                     HLFSSETYKDYLSTLWHDLNDGEDLKSMQDLYETPKYKLSKDDQEEMKELKEEGVYAS
                     MQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQAIVAPMDGVVSL
                     DGDNVILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDVIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATASSWDDETWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPAIYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISQADSAISFAYTTK"
     gene            complement(9261..9449)
                     /locus_tag="VQ860_001381"
     CDS             complement(9261..9449)
                     /locus_tag="VQ860_001381"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119805.1"
                     /translation="MVYRVCKPPSQSVYSGVCHRLALTSKIAIGFRSGVRHRLALMSK
                     ITIRLTMSRLLIYTIYST"
     gene            9468..10034
                     /locus_tag="VQ860_001382"
     CDS             9468..10034
                     /locus_tag="VQ860_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119806.1"
                     /translation="MANSRDYRNPNYTEKIKLQRFFTQLQIAASFFKEHFVGKIMYYE
                     TEIESVELHFSPTNFMHLCGVDYQKGAGSFFDDCLNRHVIIDELKIKKDGTTMQKLQV
                     LGSIEELLGKHVHLTGSGRYLYLEFDYALRTRKQILALTLKETSRKIVPQSLLDLKRK
                     TVFPKGQKVISIYSKHLQTSELFYYLKD"
     gene            10186..10596
                     /locus_tag="VQ860_001383"
     CDS             10186..10596
                     /locus_tag="VQ860_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HET3119807.1"
                     /translation="MEGIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEVEE
                     GTNPLEKDLQDIDQTSITEPSSVFMEMKQKISDMMESHYKEFIQALISIETGIENEQD
                     LEDLYTYYMRTDSISLLSSDLETSPQKVEMEIEL"
     gene            10644..16874
                     /locus_tag="VQ860_001384"
     CDS             10644..16874
                     /locus_tag="VQ860_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3119808.1"
                     /translation="MEVMKLLAMFRGTIPKDREKMDLFLRYQAQHFDEKWQDLVESFL
                     VEEGKIEEIPHVYSFHQDIISFLEASSENNDQDLESYTRNFGQAGLSKLSQLSNFEKN
                     LVLEVATYNLSTRFYIQSEKEKLTPLSELVCHQKQDVNLVNVYRVANNLSDRISRDIE
                     EFLLMVDSKELKKEVLEIHFEEKEGDVLAYLGSELMATLDTVTDLVHHEENYQQLPLT
                     QKLKIITHFDEVKAIREKSKQVAESLSPSSDIEQETEETNSFSNIDKIVEEALREYPI
                     GSQVSYKGQVFQLVSIENAQLNDLVRLELFKDSNQLFEENPILYLNSLEEIEQVLSHV
                     ELEKEDSEIEIDSSSESQEIDLFSYLEEENENEKEKEKDKETETLIVGIEETDVPVQD
                     FVFPDDLEDFYPKTNREKIETNIAAIELVKRLEKEGRQANPEEQELLAKYVGWGGLAN
                     EFFDELNPKYETERLTLKSLVSKSEYSTMKQSSLTAYYTDPMIIRQIWQKLLDDGFEG
                     GRILDPSMGTGNFFAAMPRSIRDKSELYGVELDSVTGAIAKQLHPNTHIEVRGFEEVP
                     YQNNSFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTM
                     DKRTDNVLQEIKSNTHFLGGVRLPDTAFKKIAGTRVTTDLLFFQKDQAKNLNEEELVF
                     SGSIPFEEDKRVWINPYFDGKYNTQVLGQYEVRNFNGGTLNVKGVSETLVTEIMKAFE
                     NVEAPKQIDNSLKAPVFIQEEVDNSIPSRICEDLALYSFGYEGNQIYYRDTHGIRKSS
                     KVDEISYYVDEKGEFKAWDSSLSEHKIDRFVQLHLTDEEALDVYKSEEASKRGKYKGL
                     FKKTVFYESPLSDKDISRIKGMVDLRETYQALIEIQRHPDYSRSDFQILLSKLNRDYD
                     RFVSQFGYLNASVNRNLFDSDDKYSLLASLEDEYIDSKDQKVKYKKSLAFEKALVRPE
                     RVITRVSTALDALNSSLSDGRGVDLDYMVSIYPEHSQAAILDELGDQILMDPESYLRG
                     ERKYLSKNQFLSGDILNKIEVVQLLVEENNQEYDWNHALDLLESVRPPRIHLADIEFK
                     IGSRWIPQSVYGKFAFECFTNREFELSSPDVEQVIEVNPVDGQVHLRTSFAYRYPSAK
                     DSSLGVSGSRYDTGRKIFENLLNSNQPTITMTVTEGEKKKTITDLEKTSVLRAKEQHL
                     QELFQEFVSRYPEVQQVIEESYNRLYNRTVSREYDGSHLVIDGLAQNISLRPHQENAI
                     QRIVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKF
                     FPTKKVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDK
                     LNELREIKTHSENKYTVKEAEQSISGLEKQLEELQRFNRDSFIDFENLGIDFLFVDEA
                     HHFKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDFKNIVFATGTPVSNSIS
                     ELYTMMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLP
                     ELMKIYKETADIQTQDMLDLPVPEAHIIPIESELTENQKLYLEELVMRSDAVKCGTVD
                     PSQDNMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMGNKATQMI
                     FSDIGTPKKKDNGFDVYSEIKALLVDRGIPSKEIAFVHDANSDEKKNSLSRKVNAGEV
                     RILLASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQQRNGRIIRQGNENKEVDIYHYI
                     TKGSFDNYLWATQENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKY
                     KMELENDLTLLENQRRAFQRSKDHYRHTISYCEENMPILEKRLSKYEGDIQQSEISKD
                     QAFSMTVGKQAFDQRAEAGESLHRLIRHNQADSKEFRTLASYRGFDIKMLSLPINQPL
                     PETFSVKIVGENQYSVSLDLYSPLGTIQRLQHTIDHIKEDQVKTQNLLDELKDKWTTA
                     KVEIEKNFPKEEDYQTKKAEYDVLAPLIETETDLDIIDQALRQFHEKGKEKQEQLSFE
                     LD"
     gene            16949..17233
                     /locus_tag="VQ860_001385"
     CDS             16949..17233
                     /locus_tag="VQ860_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119809.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSK
                     RELTSQLEISLQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID"
     gene            17247..17543
                     /locus_tag="VQ860_001386"
     CDS             17247..17543
                     /locus_tag="VQ860_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119810.1"
                     /translation="MNDLLLIPVIFLAVGGILILLWRLFLIASRLFLIGFVSFLIFVE
                     VYGIYLFFTEPTLYFDDIRQHGLTSFTAVYLFINLMLVLGFSWRFINSMNKEKM"
     gene            complement(17557..17754)
                     /locus_tag="VQ860_001387"
     CDS             complement(17557..17754)
                     /locus_tag="VQ860_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119811.1"
                     /translation="MNKLKEENLRRALSHIERHKQAINTTNNSEDNDFHKLLLQFSYE
                     VYERIKANKKPYPNLDSDKVF"
     gene            17914..18555
                     /locus_tag="VQ860_001388"
     CDS             17914..18555
                     /locus_tag="VQ860_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3119812.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELTS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKVTPKTLEESSSIPSLPNTTTK"
     gene            18565..19650
                     /locus_tag="VQ860_001389"
     CDS             18565..19650
                     /locus_tag="VQ860_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HET3119813.1"
                     /translation="MEIEECKQISILDVANRLGISFKQVSSRVYEHPEHDSFRIFSTT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKDALAFLSEEPFQKEAVQEKRERPFYYPLKRV
                     EDSNCSLARYYLTKCRGISEEIVQKMIQQGLMAQASWKTNETVELVIVFKSFDHRHKL
                     QAASLQGIYKNPALSRERLKTILKGSHGHIGISFDIGKPNRLVFCESFVDLMSYYELH
                     QQSLTDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTVIPSKLLPLMNTIRDTTT
                     YFDNHPDLLTLAVDCDDAGKDFSDKLFQAGLPVLLDLPDNESGKEKIDWNDILREKKS
                     DLQLILESAKETLRNQPVRQTSQCLEL"
     gene            19701..19934
                     /locus_tag="VQ860_001390"
     CDS             19701..19934
                     /locus_tag="VQ860_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119814.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     gene            19931..20314
                     /locus_tag="VQ860_001391"
     CDS             19931..20314
                     /locus_tag="VQ860_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HET3119815.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFRNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIESSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            20352..20624
                     /locus_tag="VQ860_001392"
     CDS             20352..20624
                     /locus_tag="VQ860_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119816.1"
                     /translation="MFTKIFKKNQDNSDIFKKLIHRLSDMSVQDLEKIDRLLDIIFTP
                     EQESEQLKTETTYREETLDDTLKKAKNQLHKEQLEKNLERFRKNSQ"
     gene            20694..>20762
                     /locus_tag="VQ860_001393"
     CDS             20694..>20762
                     /locus_tag="VQ860_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3119817.1"
                     /translation="MIGKNIKSLRKTHDLTQHDFARI"
BASE COUNT         7124 a         3299 c         4262 g         6077 t
ORIGIN      
        1 aaaaaagact acattgaatt taaacgtgtt ggtatcgttg atgggaaggc agtagaagtc
       61 actcttcgag aaccttattc gagagatcta ctgaaggttg tcaagtcgat taagcaacgt
      121 cagaaattga tagcttatcg ttataaagaa ggaaagctgc tatttgtgaa gaaggaggca
      181 tcagatgtcc tctgaacaac aggaacgaat ggcagttcaa tatgcagagc gtagtctttt
      241 atttactgta aaaagtcttt taaagattct agaatggtct agacgtcagg ctttagcaca
      301 ggattccgcc tataagatag gagtgcagaa attagaagaa ttgctacaat ctccctatgc
      361 gattgatacg attaatctga aaaaagattt tttagacaaa ccaattgata tagagaaatt
      421 taaagctttt ttagaaaaag aagagattcc tttagccatc gcttggcaag gggattctct
      481 acatttctac gcgaaagacc gttcgatttt agacaatcat ttagaccatc ttttagaaaa
      541 aatggttaat gatccggaga aattagctga ttttaccatg gataagtcat tagatgatgc
      601 tattgatgaa gctaaatccc aaattacctt tagacaagaa ggagccgtca aacagaaaga
      661 gatggtgaga tgatgtacag tggaaaaaaa ttcctactat tctcactgtt aggtatctta
      721 ctaggctatc tttttcatcg tttgacgctt ttgtatgatt cctatactgg aaatacctta
      781 gataaatgga ctcatcttct gatggaaggt caagatgaag ttcttcagtc gccatggaat
      841 gtttctttta ctggaaaatc aagtgctttt tttctactag gttttgtgat gatgttactg
      901 gtttatctct atctagagac tggtaaaaaa caataccgag aaggggtaga atacgggagc
      961 gcccgttttg gaactctaaa agaaaagaag ctcttttacg gtaaggaatt ttctcatgat
     1021 acgatcttag cacaagatgt tcgtttgaca ttattagata aaaaaccacc ccaatatgat
     1081 agaaataaga atattgcggt gattggaggt tcaggaagtg ggaagacatt tcgctttgtg
     1141 aaacccaatc tgattcagat gaatagttct aatattgtag tggatcctaa agatcacttg
     1201 gccgagaaaa caggcaaact ctttttagaa catggctacc aagtaaaggt gttagattta
     1261 gtcaatatga agaactcaga tggctttaat ccttttcgct atatagaaac agaaaacgat
     1321 ttgaatcgca tgctgactgt ttattttaat aacaccaaag gctctggctc ccgaagtgat
     1381 ccattttggg atgaagcttc tatgactttg gttcgagctt tagcctctta cttagtcgat
     1441 ttctataatc cacctaaaac aagagaacag ctcatagaag aaagtcgttt aagtcaaaag
     1501 gaatatcaaa acttgttgaa acgtcaaaaa aaagaagtgg aagagcgaaa aaaacgaggt
     1561 cgttatccaa gttttgctga aatctcaaaa ctcattaaac acttatctaa gggtgaaaac
     1621 caggaaaaaa gtgtcttaga aattctattt gaaaattatg ctaaaaagta tgggactgaa
     1681 aattttacca tgcgaaattg ggcagatttt caaaattata aggataagac tctggattct
     1741 gttatagctg taaccactgc taaatttgcc ctcttcaata ttcaaagtgt catggacttg
     1801 accaaaagag atacccttga tatgaagaca tggggcaagg aaaaatcaat ggtttactta
     1861 gttatcccag ataacgatag tacctttcgc tttctttcag ccctcttttt ttcaaccgta
     1921 tttcaaaccc taacaagaca agcagatatt gattttaagg gtcaattgcc tcttcatgtg
     1981 agagtttact tagatgagtt cgcaaatatc ggagaaattc cagattttgc tgaacaaacc
     2041 tcaacagtcc gttctcgaaa tatgagtctc gttcctattc ttcaaaatat tgcccaactt
     2101 caagggctct ataaagaaaa agaagcttgg aaaaccattt tggggaactg tgatagctta
     2161 gtctacttag gtggtaatga tgaagatacc tttaaattta tgagtggctt actcggtaaa
     2221 caaaccattg atgttcgaaa tactagtcgt tcctttggcc aaacaggttc aggatccctt
     2281 tctcatcaaa agattgctcg tgacttaatg acacccgatg aggtcggaaa tatgaaacgg
     2341 catgaatgct tggttcgaat tgccaatatg cctgtcttta aaagcaaaaa atacaattcc
     2401 actaagcatc caaactggaa gtacctagct aatcaagaaa gcgatgaacg gtggtggaac
     2461 tatcaaatca atcctttgaa tcaaagacaa gaaaattatc ttgacgacct tagaattcgt
     2521 gatttaactt ttgaatctag tttaaaataa aaatagaaaa gaggaaatag atgattacgc
     2581 attttaaagg ttttgtttat ggagtagacg caagtgctat gtttgcacaa gctatgtctt
     2641 tgttacagaa gggattgatt gcagttggtg cctttctcgt tgttgtgggg attgtcaacc
     2701 ttgcaaccaa cattaaagat ggtggaccag gtgttcggaa tgccattctt gaaattgtcg
     2761 gtggtgttat ggtaggggct gctggagcct ttgtaaccca gatttcaatt taggaggata
     2821 aacaatgaca tgaatcttag tttagtctca ccctttgttt accttgcatc tgaaaaaata
     2881 tcagctgaaa atttatttga aggatttaat gtggatttac aatctacggt agatctgatt
     2941 aaatccctat ctagctacaa tccaacagtt tggacttata tgtctagtat tactaaaagt
     3001 gtcatgcagc ctcttggagt tgcgatttta tcagttgttc tcatcttaga attttcgaag
     3061 atggcaaaga agattgctaa ctctggtgga gcgatgacct ttgaagcatt agcgccgatg
     3121 ttgattagtt atattatggt cgcagtggtc attaccaata ctaccgttat agtagaagct
     3181 atcatcggga ttgcgagtca cgccatcgaa caagtggcct cgattgtggc tcacggtggg
     3241 gcgaagtatg atacactctc tggattaaaa ggttcaggat ttattggccg gatgattgtg
     3301 ggctttttcg ctctccttat ctggcttgtt cggatagtaa gtgcagccat ggttaatctt
     3361 ttggtatcta ttcgatttat tcaactctac cttatgatcc catttgcccc tcttacgatt
     3421 ccaacatttt taagtgatga atggaagtct attggtattg gctatttaaa aaatattatg
     3481 gtctatgcgg tacaaggggt tctcattttt ctgattgttt ctcttgttcc tttgtttgaa
     3541 tctgctggga aaatagctgt ttcaaatggt gcaggagtct tgcaatcact tgcgattatg
     3601 tttggtagtt tagtacaagc tatcttactg attattgccc tcgttggttc tcaacgtacg
     3661 gctcgctcaa tcttaggtat gtaattagat aaaggctagg aagtgattgc ttcttagcct
     3721 ttttagaaag gaaagtcatg aatacacgtg tctttaaaga catctcaaaa taccaacaca
     3781 gggcttggtt aggtttcacc acaagacaaa tcatctttgt tttaccagcc tttattgtca
     3841 caattattgt tttgggcttg aatctctttt tctggcaatt tggagattgg tttgtttacg
     3901 gttttgtgtt tgcttttacc atccccctaa tgctttttgg agtctataaa cccaatgatt
     3961 tatattttga acattatttg aaataccgtc ttcattttga attaacggtt cccctacgca
     4021 caattacagg aaagaaagga cctgaacatg aaaagaaaat caaatacatt aaagaaacaa
     4081 aaaacttcaa tgactaataa aaaggaagaa gttaaaggga aaaaagagga agtgttaccc
     4141 tcaacggcta atactctttc ctatcaagcc ctgtatcaaa atggtctgat gcaggtaaaa
     4201 gaagattatt tctcacaaag ctatttactt ggtgatgtca attaccagac cgttggttta
     4261 gaagataagg gcgcaatcat tgagaagtat tctgatttga ttaactcact agatgaccaa
     4321 accaacttcc aattgactat ctttaataaa agattgaatt tagaaaagtt tagacaaagt
     4381 gttttgtatg aggaaaaaga agatggatat gatacctatc gtaaagaatt gaatcggatg
     4441 atgaatcaga atttagatag tggtgaaaat aacttttcgg ctgtaaaact gattagcttt
     4501 ggaagaaagg attctaatcc caaacaagcc tatcgttcct tgtctcaaat aggagaatat
     4561 ttcaagagtg gtttctcaga aattgatgct cgatttgaat ccttggctgg agaagatcgt
     4621 gtgaacttgt tggccgacat gcttagagga gaacaccatc ttcctttttc ttaccgtgat
     4681 ttaacgagat ctggtcagac aactcgtcac ttcatagccc ctaatctctt ggattttaaa
     4741 aacaagaatt acctacaaat caatgaccgc ttattacaga ttgtctatgt cagagactac
     4801 ggcatggaat taggggatca gtttattcga gaccttatgc aaggagattt ggaattgatt
     4861 gtaagccttc atgctcaaag ttcgaccaag gcagatgcca tgaagaaact acgaacaaag
     4921 aagaccttga tggaatccca aaagattggg gaacaacaaa aactagctcg tacaggtatc
     4981 tatttggaaa aagtaggtca tgtattagaa agtaatatcg atgaagctga agaactttta
     5041 aaaaccatga ccgagacagg tgataaactg tttcaaacgg tcttcttgat tgggatcttt
     5101 ggtcaggatg aagaagaact caaacaagct ctagatacga ttcaacaagt ggccggctca
     5161 aatgacctaa tgattgataa acttccatat atgcaagaag cagcctttaa tagtttgctg
     5221 ccatttggtt gtgatttttt agagggagta tcacggagtt tattaacatc taatgtagca
     5281 gtgaactcac cttggacttc agtagactta caagaccgca gtgggaaata ttacggtatc
     5341 aatcaaatct caagcaatat tattactatt gatcgaagct tattaaatac accgtctggt
     5401 ctgattttag ggacatctgg agctgggaaa gggatggcaa ctaagcatga gattatcacg
     5461 accaaaatca aggaatctgg tgaaaatact gaaattatca tcgtggatcc agaagcagaa
     5521 tacagtgtca ttggacgagc ttttggggga gaaatgattg atattgcgcc agattcccaa
     5581 acctatctca atgtacttga cttgtctgat gaaaatatgg atgaggatcc tgttaaggta
     5641 aaatcagaat ttcttttatc ctttatcggc aagttattgg ataggaaaat ggatggaaga
     5701 gaaaaatcga ttatcgaccg agtcaccaga ctcacctatc agtcatttaa agagccttct
     5761 ttggaagaat gggtctttgt cttgagtcaa caaccagaag aagaagcgca gaatttggca
     5821 cttgatatgg aactgtatgt cgaaggttct cttgatattt tttctcataa gaccaatatt
     5881 cagacaggat ctaacttctt aatctataac gttaaaaagt taggagatga gctgaaacaa
     5941 atcgctctta tggtagtgtt tgatcagata tggaatcgtg ttgttcggaa ccaaaaatta
     6001 gggaagaaga cctggattta ttttgatgaa atgcagcttc tcttattaga taaatatgcc
     6061 agtgatttct tctttaaatt gtggagtcgt gtcagaaaat atggagctag tccgactggg
     6121 ataactcaaa acgtcgaaac cttattgtta gatccaaatg gtagacggat tattgcaaat
     6181 agtgaattta tgattctcct caagcaagca aaaaatgacc gagaagaact ggttcaactc
     6241 ttaggcttgt caaaagaact cgaaaaatac cttgtcaatc cagaaaaagg ggcaggactg
     6301 ataaaagctg gttcagttgt cgtacccttt aaaaataaga ttcctcaagg tactcaattg
     6361 tttgatatca tgagtacgga tcctgataaa atggcttcta attaagggga agtagaatga
     6421 aggataaaag aaaaatcata cgtgcccgaa aggcatttag aagaagccta aaagatgaga
     6481 aaaaattctt gaaaaaagga aagaaggagg taaggaaaca gaaaaaagat tccgctgtac
     6541 tggatgaaaa agcatggaaa aaagagataa aagaaaagct agaggagatg agagaggctt
     6601 caaaggagag agtaaaacaa gcaaatgaag actacaatca tattcttcaa aatagtcctc
     6661 catctctttt gaatcgcaaa gaattaagag acagacggtt gcctcatgct aggaaacgat
     6721 tgaaaatagc caagaagcaa tttagagaag ccaaggtaga agcaaaagaa gaaagaaaag
     6781 agggtcgtaa agaaagaaaa accaatcaaa aatttctcta cggtcaggaa tcgaaagcaa
     6841 aatcaaattt tttctttcaa gggaagagtt tagaagaatt aaaagctaag aaagaagtca
     6901 aggacgccaa agaaaattta aaatctacta aacaagccta taaatccaaa aaggttagta
     6961 ggaaagccaa aactttcctt tatgtccttg gacgtgaagg tggagagtta gcttcagaaa
     7021 atgaagattt agaaggctat cgcacacttc aagagaccat tagaaaaggg aaacgctaca
     7081 gtcggctttc ttataatctt ggaaaagcta gtgtcaaaac aggacaagca acaggtcgtt
     7141 ttaccaagaa aagactgacc aacacaaaag agcgatacca tcattttaag gatggaaaag
     7201 gatggaaact agcgaaagat aatccaagtt cctttaaaaa tcggtatcga aaattaaaga
     7261 aacaaggcct tacaagtgta cgaaatatct atcaaaaact aaaagcagcc ttttccttct
     7321 ttacatttgc ggctgggaat cctgcaacct ggatagttgg aggaatagtc tttcttcttt
     7381 tacttatgat gagcttcttt ttaggatttt catctgctag tttaattcaa caagatgaat
     7441 ttgaattaac aaaagcttat acccacctaa cttgggaaga cgcagaacat acccgaacca
     7501 atgacaaagg aattacctat tacacaaaag ttgatgatgt gatggggtat atgaacttta
     7561 aattccatga ctatgagtta cacaaaccag ttcacttatt tagttcagaa acttacaagg
     7621 attatctatc tactttgtgg catgatttaa acgatgggga agatttgaaa tccatgcaag
     7681 acctttatga aactcctaag tataaactat cgaaagacga tcaagaggaa atgaaggaac
     7741 taaaagaaga aggtgtgtat gcttccatgc aggaattgga caatccattt gaagggaaaa
     7801 gtaacgaaga tagtttaacc atgacttatc gttatggata ctatgattta gacggaaaac
     7861 ctactcttca ggagtacatt ctactagaag ctaaagctca ccaagcaatt gtcgcaccaa
     7921 tggatggagt tgtatctcta gatggcgaca atgttattct cactaacgga aaaggagaaa
     7981 acgagagtcg cttaacctta tattccattc ataatggccg tgcgattgag gggacaagag
     8041 tcctaacggg tgatgttatt ggtgagacac cagatgatac aggtttgaaa gtttcctatc
     8101 aaaagtataa gaacaagaaa gaaaaattgg tgtatgttaa tccgcaattt tattttccaa
     8161 aagtcattca acttcagaca actatcttac ctgccattgg tcagtttggt ggggatgagt
     8221 ttgaacgagc gaaacatatt tatgagtttt tgaaatctca aggggcaagt ccccaagcca
     8281 ttgcagctat tttaggaaat tggtcggtag agtcttctat caatcctaaa cgagctgagg
     8341 gagattattt atctcctcca gttggcgcta ccgcttcctc atgggatgat gaaacctggt
     8401 tagcgattgg aggtccagcc atttatagtg gtgcttatcc taatatcctt catagaggtt
     8461 tggggttagg tcaatggacg gatactgcag atggttcaac acgtcataca gctttattga
     8521 attatgcaca tagcaaaaat aagaagtggt atgatttaga cctccaactt gattttatgc
     8581 ttcatgggga tagtccttac tatcaaagtt ggttaaaaga tttctttaaa aatacgggca
     8641 gtgcagccaa tctcgcccaa ctcttcctca cctattggga gggaaattct ggtgacaaac
     8701 tactggaaag acaaaccaga gcaacggaat ggtattacca aattgaaaaa ggcttcagcc
     8761 aaacaaatgg aggacaggca aaaagtgacc cacaatccct tgaaggggtt cgtggggact
     8821 tgtatgatca ttctgttcct ggtggtggag atggtatggc ctatgcctat ggacaatgta
     8881 catggggcgt tgcggctcgt atgaaccaat taggcttaaa attaaaagga agtaatggag
     8941 agaagatttc aattattaat accatgggaa atggtcagga ctgggttgcg acagcttcaa
     9001 gtcttggtgg ggaaactggc tctacaccaa gagcaggtgc cattgtttct tttgtgggag
     9061 gtacacatgg tacaccagcc atctacggtc atgtggcttt tgtcgagaaa gtatatgatg
     9121 acggttcttt ccttgtgtct gaaaccaact atggtggcaa ccctaactat acctttagaa
     9181 aaatctctca agcagatagt gcaataagtt ttgcctatac tacgaaatag aagagtttac
     9241 acttgaaatt ttaaccattt tcaggtagaa taaatagtgt agatgagtag tcggctcatg
     9301 gtcaatctga tagtaatctt ggacataagg gccaagcggt ggcggacacc agaacgaaat
     9361 ccgatagcaa tcttggacgt aagggccaag cggtggcaga caccagaata aaccgactga
     9421 ctaggtggct tacagactct gtaaaccacc ttttttgtga ggaaaatatg gcaaattcta
     9481 gagattatcg taatccaaat tacaccgaaa aaataaaact tcagcgtttt tttactcagt
     9541 tacaaattgc ggcttctttt tttaaagaac acttcgttgg caaaatcatg tattatgaaa
     9601 cagaaataga aagtgttgaa cttcattttt cacctactaa tttcatgcac ctatgtggtg
     9661 ttgattacca aaaaggtgca ggtagtttct ttgacgattg tttaaataga catgtcataa
     9721 ttgatgagtt gaaaataaaa aaagatggaa ccacgatgca aaagttacaa gttttaggat
     9781 ccattgagga gttattggga aagcatgttc atctaactgg ttcaggacgt tatttgtatt
     9841 tggagtttga ttatgctcta cgtacaagaa aacagatact agcattaaca ttgaaagaga
     9901 catcaaggaa aattgttcct caatctttat tagatttgaa gagaaagaca gtatttccaa
     9961 aaggtcaaaa agtaatttca atttactcaa aacatttaca aacgtcggaa cttttttatt
    10021 atttaaaaga ttagtttaca tatcttttgt ggcataaaat atatttttat cattttcagg
    10081 agaacgcagt tttggctcgt tctctttttt tgttgtgata cttctttcaa ggaatatttg
    10141 gtaggattgg agtgaaaaaa gattaactag gaaagaagga agtatatgga aggcatttat
    10201 caacgtgatt cggatcaaga tggattaact gatgctcaag aattggcgct aggaaccaat
    10261 cctcttagcg cagattctga tggtgatgga cgttcagatt tagtggaagt agaagaagga
    10321 accaatccct tagaaaagga tttacaagac atagaccaaa caagtataac tgaaccgtct
    10381 tcagtattta tggaaatgaa acaaaagatt tcagatatga tggagagtca ctacaaggaa
    10441 tttatacagg ctcttattag tattgaaaca gggattgaaa acgaacaaga cctagaagac
    10501 ttatatactt actacatgag aacagattct atttctcttt tgtctagtga tttagaaacc
    10561 agtcctcaaa aggttgaaat ggagatagag ttgtagggga atcatgtgat tctcctattt
    10621 tcgtatagat gaaaggagcg agtatggaag taatgaaatt attggctatg tttcgtggaa
    10681 caattccaaa agatagggag aaaatggacc tatttcttcg ctatcaggcg caacattttg
    10741 atgagaaatg gcaggacttg gtagagagtt ttttggttga agagggcaag atagaagaga
    10801 tacctcatgt gtattcgttt catcaagata ttatttcttt cctagaggct agttctgaaa
    10861 ataatgacca agatttagaa agttacacaa gaaattttgg acaagcaggt ctaagtaaat
    10921 tatctcaatt aagtaatttt gagaaaaact tggtgctaga agtcgcaacc tataaccttt
    10981 ccactcgatt ttatatccaa tctgaaaaag agaaactaac accattaagt gagcttgtat
    11041 gtcatcagaa acaggatgtc aatttagtca atgtctatcg ggttgcgaat aatctatctg
    11101 accgcattag tagagatata gaggagtttc ttctaatggt tgactcaaaa gagcttaaaa
    11161 aagaagttct tgagattcat tttgaagaaa aagagggaga tgttctagct tatttgggtt
    11221 cagaattgat ggctacttta gatactgtta cggatcttgt ccatcatgaa gaaaactacc
    11281 aacaacttcc actgacacaa aagctgaaga ttattactca ttttgatgaa gtaaaggcta
    11341 taagagaaaa gtctaagcaa gtagcggaat ccttatctcc ttcaagtgat attgaacagg
    11401 aaacggaaga aacgaactcc ttttctaata tcgataaaat tgtagaagaa gctttgaggg
    11461 aatatccaat cggttcacaa gtaagttata aaggacaagt atttcagttg gtttcgattg
    11521 aaaatgcaca gttaaatgac ttagttcgcc tagagctatt caaagattcc aaccagttat
    11581 ttgaagagaa tcctatctta tacttgaaca gtttggaaga gattgaacaa gtattgtctc
    11641 atgtagaact tgaaaaagaa gattcagaga ttgagattga ttcatcaagt gaaagtcagg
    11701 aaatagattt gttttcctac ctggaagaag aaaatgaaaa tgaaaaggaa aaggaaaagg
    11761 ataaagaaac agaaacgctt attgtaggca tagaagagac ggatgtccct gttcaagatt
    11821 ttgtttttcc agatgattta gaggactttt atcctaagac aaatcgagaa aaaattgaaa
    11881 cgaatatcgc cgcaattgaa cttgttaaaa gattagaaaa agagggacga caagcgaatc
    11941 cagaagaaca agagctacta gccaagtatg tcggctgggg tggtcttgcc aatgaatttt
    12001 tcgatgaact caatccaaag tatgaaacag aacgtttaac tcttaagagt ttagtaagta
    12061 aatcagagta ctccactatg aaacaaagtt ctctcacagc ctattataca gacccaatga
    12121 ttattcgcca gatttggcaa aaattactgg atgatggttt tgagggagga aggatattag
    12181 atccttctat ggggactggg aacttctttg cggcgatgcc tagaagtata cgagataaat
    12241 cagaactcta tggagttgaa ttagacagtg tgacaggcgc aatcgcaaaa caactccacc
    12301 ccaataccca tattgaagtg cgaggatttg aagaagttcc ctatcaaaat aatagttttg
    12361 atttagtctt aacgaatgtt ccttttggaa attttcgcat tgccgataaa aactatgata
    12421 aaccttacat gattcatgat tactttgtca aacactcact tgatttagta agagacggag
    12481 gacaagtgtc gattatctca tctataggga caatggataa gcggacagat aatgtcttac
    12541 aagagattaa atctaacact cattttttag ggggagttcg tttgccggat acggctttta
    12601 aaaagattgc aggtactcga gtgaccacag atcttctctt ctttcaaaag gatcaagcaa
    12661 agaatcttaa tgaggaggaa cttgtcttta gtggctctat tccctttgaa gaggataagc
    12721 gtgtctggat caatccttat tttgatggga aatacaatac acaagttttg ggtcaatatg
    12781 aggtgcgtaa ttttaatgga ggaactctca atgttaaggg ggtatcagaa acattagtta
    12841 ctgaaataat gaaagcattc gagaatgtgg aagcacctaa acaaattgac aattctttga
    12901 aagcacctgt ttttatccaa gaagaagtag ataattctat cccaagtcgt atatgtgagg
    12961 acttagcgct ctattctttt ggatatgagg gaaatcaaat ttattaccga gatacgcatg
    13021 gcattcggaa aagttcaaaa gtagacgaaa ttagttatta tgtagacgag aagggagaat
    13081 ttaaagcctg ggacagttct ttgtctgaac ataaaataga tcgattcgtg caacttcatt
    13141 tgacagatga ggaagcacta gatgtataca agtcagaaga agcgagtaaa agagggaaat
    13201 ataagggact gttcaaaaaa actgtctttt atgaaagtcc cttatcggat aaggatatta
    13261 gtcgcattaa gggtatggtt gatttgagag agacctatca agccttaatt gaaattcaac
    13321 gtcatccaga ttatagtcgg tctgattttc agatattact tagtaaactc aatcgtgatt
    13381 atgaccgttt tgtaagtcaa tttggatact tgaatgcctc agttaatcgg aacttatttg
    13441 atagtgacga taagtattct ttactagcaa gtttagaaga tgaatacatt gattctaaag
    13501 atcagaaagt aaaatataaa aaatctttag cctttgagaa agcattggtt aggccggaga
    13561 gagtgattac aagagtatca acggctttag atgccttaaa ctctagttta tcggatggta
    13621 gaggggttga tttagactat atggtatcaa tttaccctga acatagtcaa gctgctattt
    13681 tagatgagtt aggtgaccag attttaatgg atccagaaag ctatttaaga ggtgaaagaa
    13741 aatatctttc taagaaccag tttttatcag gagatattct caacaagata gaagtagttc
    13801 aactattagt agaggaaaac aaccaagaat atgattggaa ccatgcttta gatttgttag
    13861 aatctgttcg ccctccaagg attcatctgg cagatattga gtttaaaata gggtcacgtt
    13921 ggattcctca atccgtttac ggtaaatttg cctttgaatg ttttaccaat cgtgaatttg
    13981 aattgtcttc acctgatgtt gaacaagtta ttgaagtgaa tcctgtcgat gggcaggttc
    14041 atttaaggac atcatttgct tatcgctatc caagtgccaa agatagtagt cttggagtta
    14101 gtgggtcacg ttatgataca ggaagaaaga tttttgagaa tttacttaat tcgaaccaac
    14161 cgacgattac tatgactgtt acggaaggag aaaagaaaaa gaccatcaca gatttggaaa
    14221 aaacctctgt tctaagagca aaagagcagc atttacaaga gctctttcaa gaatttgtct
    14281 cacggtatcc agaagtccaa caagttattg aggaaagcta taatcgtctt tataatcgaa
    14341 cggtaagtcg agagtatgac ggtagccatc tagtcattga tggattggca caaaacatca
    14401 gtcttcgtcc tcatcaagag aatgccattc aaagaatcgt agaagaaaaa agagccttgt
    14461 tagctcatga ggtaggttca ggaaagacct tgaccatgct tggtgctggg tttaaattaa
    14521 aggagttggg gatggttcat aagcccttgt atgtagtacc ttctagtttg tctgctcaat
    14581 ttggccaaga aatcatgaaa tttttcccta ctaaaaaagt ctttgtgact actaagaaag
    14641 atttcgttaa ggcaagaaga aaacaatttg tgtcacgtat tattacagga gattacgatg
    14701 ccattgtcat tggggattct caatttgaaa aaatccctgt cagtaaggaa agacagatga
    14761 attatatcga ggataaactc aatgaattac gagagattaa aacacattct gaaaataagt
    14821 atactgttaa agaagcagag caatcaataa gtggtctaga gaaacaattg gaagaactcc
    14881 aacgctttaa tcgtgatagt tttattgatt ttgagaactt aggaattgat tttctctttg
    14941 tggatgaagc acatcacttt aaaaatattc gtccaattac gggacttggg aatgtagcag
    15001 ggattaccaa tacaacctct aagaagaacg tggatatgga aatgaaggtt cgacagattc
    15061 aggaagagca tgattttaaa aacattgtct ttgcgacagg aacacctgtt tccaattcta
    15121 ttagtgagtt atatactatg atgaactata ttcaaccaga tatcttaaaa cgctatcaag
    15181 ttgattattt tgactcttgg gtaggtgctt ttggagaaat tcaaaactct atggaattag
    15241 ctcctacagg ggataagtat cagcctaaga aacgatttaa aaagtttgtc aatctacctg
    15301 agttgatgaa aatctataaa gaaacagccg acattcaaac acaagatatg ttggatttac
    15361 ctgtaccaga agcccatatt atccctattg agagtgagtt aactgaaaac cagaaactct
    15421 atttagaaga attggttatg aggtcagatg cggtcaaatg tggaacagtt gatccgagcc
    15481 aggataacat gttaaagatt acgggtgagg cacggaaact agctattgat atgcgtttat
    15541 tggactctag ctatagtcta gcagacaatc ataaactgct tcaggtagtt gataatgttg
    15601 aaagaattta tcgtgaggga atgggaaata aggctactca gatgattttt tcagatattg
    15661 gaacacctaa gaaaaaagat aatggctttg atgtttattc tgaaataaag gctttattgg
    15721 ttgatagagg aatccctagt aaggaaattg cctttgtaca tgatgccaat agtgatgaaa
    15781 agaagaatag tttgtctcga aaggtcaatg caggagaagt gcggattctt cttgcatcaa
    15841 ctgaaaaagg aggaacaggt ttaaatgttc agagcaagat gaaagcagtt catcacctgg
    15901 atgttccgtg gagaccaagt gacattcagc aacgcaatgg acggattatc cgacagggaa
    15961 atgaaaacaa ggaagtggat atttaccact atattaccaa aggttcgttt gataattatc
    16021 tatgggcaac tcaggagaac aaactccgtt atattaagca gattatgact tctaaggagc
    16081 cgattcgtgc tgcagaagac attgatgagc agaccatgac agcttctgat tttaaggcac
    16141 tagcaacagg taatccttat ctcaaatata agatggaact agagaatgat ctaactctat
    16201 tagaaaatca aagacgcgcc tttcaacgca gcaaggatca ctatcgtcat acaatctctt
    16261 actgtgaaga aaatatgccc attcttgaga aacgattaag caagtatgaa ggcgatattc
    16321 aacagtctga aatatcgaaa gaccaggcat tttctatgac ggtaggtaag caagcttttg
    16381 atcaacgagc tgaagcaggt gaatctctac accgtcttat ccgtcataat caagctgaca
    16441 gcaaagaatt tcgtacccta gcaagctatc gaggatttga cattaaaatg cttagtcttc
    16501 caataaatca acctcttcct gaaaccttct ctgttaagat tgtaggagaa aatcagtatt
    16561 ctgtcagttt agatttgtat tctcctttgg ggacaattca aaggcttcag catacaattg
    16621 atcacattaa agaggaccaa gtgaaaactc agaacttatt ggatgaatta aaggataaat
    16681 ggactactgc taaagttgaa attgagaaaa attttccaaa ggaagaggat tatcaaacta
    16741 aaaaggccga atacgatgta ctcgcgccat tgattgaaac agaaacggat ttagatatta
    16801 tagatcaggc cttaagacaa ttccacgaaa aaggaaaaga aaagcaagaa caactttctt
    16861 ttgaattaga ttaaaaaata tatataaata gcggacaaga aaagaaaagc gcggtagaat
    16921 aaagatagaa agaaacgagg taacgattat gatggaagat acctattatc aattagaaga
    16981 ggccttggta cagggatttc aaacgcctga agaataccaa gcctacaagg agctaaagga
    17041 acattatgag gaagtgacag gcgattacag tttttctaaa cgagaactca ctagtcaatt
    17101 ggaaatctct cttcagaatc atcgaggtgt ggactttgaa gaacatgaaa aagaggagta
    17161 tttggactta gttcaaaaat tagaagagtt tgattcctct cttgccaccc attatcgtca
    17221 attgattgac tagaaaggag aaagtcatga atgatttact ccttatccca gtaatttttt
    17281 tagcagtagg agggattctc attcttttat ggagactctt tcttattgcc agtagacttt
    17341 tcctgattgg ttttgtcagt tttcttattt tcgtagaagt ctatggaatt tatctgttct
    17401 ttactgaacc tactttatat tttgatgata tcagacaaca tggtttaact agttttacgg
    17461 ctgtgtacct tttcatcaat ctgatgttgg ttctaggatt cagttggcgc ttcattaact
    17521 ccatgaataa ggaaaaaatg tgaacttttt agatagttaa aagactttat ctgaatctaa
    17581 attcggataa ggttttttat ttgccttgat tctttcatat acttcatagc taaattggag
    17641 taataattta tgaaaatcat tatcctcact attattagtt gtatttatgg cttgtttatg
    17701 tcgttcaata tgagaaagag ctcttctcaa attttcttct tttaatttgt tcatatttat
    17761 attataaact gaagacagct ggttttgaca tttttctctg aactgtacga ttttgcgcca
    17821 gaaatgtagg aattaccttt cgttgtgatg tgataaaact tacaagttct ttttgttatt
    17881 cttgacctag tttttataga aagaaggtct aagatgttaa ataaagtcaa aactaaagcc
    17941 ttaattagtg ttggagcagt ggctgcaact agctttattc tcatgatggg atatactgct
    18001 ggtcaacact caactgctaa acaaagtcgc aaagaaatcg aattggctgc agctaaactt
    18061 gtagaggata aacaagcaga agataaagcc agcattttgt catcggatac tgtaaaagaa
    18121 tttttgactc agtactatac gaaagaaaag ctcggagaaa ataatacacg tattcaacct
    18181 tatatgactg aatcggcata ttctcaagaa ttgaccagtc aaaacgatgc catgaaccaa
    18241 gtgtataagg actatatttt ggattatcat tttgaaaaag ctgatatctt tgttaatcag
    18301 actacgaatc aagctattgc catggtctct tataatgtaa cctatgtatc tgatttaaag
    18361 aatgccaacc aatcaaagac taatcagaca gaaacaagaa cagttaagtt atcctattct
    18421 aaactaccag gtaagttatt ggtcaatcaa gtgcaggttt ggaaatctgg gttagatgat
    18481 ttagataagg taactcctaa aactttagaa gaatcatcat caataccatc actgccaaat
    18541 actacgacaa aatgatgata ttgcatggaa atagaagaat gtaagcaaat ttcaattctt
    18601 gatgtagcca atcgtttagg tatctccttt aaacaagttt ctagccgtgt ctatgaacat
    18661 cctgaacacg attcatttcg gattttttca actaccaata cttttaaatg gttttcaaga
    18721 gatattcaag gtgatgttat tgattttgtt cgacttgtta agggaatctc ttttaaagat
    18781 gctctagctt ttctttctga agaacctttt caaaaagaag ctgttcaaga aaaaagagag
    18841 agaccatttt attatccttt aaagagagta gaagattcta actgtagtct ggcaagatat
    18901 tacttaacaa aatgtagagg aatctcagaa gaaatcgtac aaaagatgat tcaacaaggt
    18961 ttgatggcac aagccagttg gaaaacaaat gaaactgttg aacttgttat tgtttttaaa
    19021 agctttgatc atcgtcacaa gctgcaggca gcaagcttac aagggattta taagaatccc
    19081 gctctttcta gagagaggtt aaaaacgatt ctaaaaggaa gccatggaca tattggaata
    19141 tcctttgaca ttggtaaacc aaatagactg gtcttttgtg aatcgttcgt cgacttgatg
    19201 agctattacg aacttcatca acaaagtcta actgatgttc gtttggtatc tatggaggga
    19261 ttaaaaaggt ctgttgtcgc ttatcaaact ttacgactga tagctgaaga aaatcagaag
    19321 ttggaatttt tagatacagt aataccttca aagttattgc ctttgatgaa tacaattcga
    19381 gatacaacta cttattttga taatcatccc gatttattaa cacttgcggt agattgtgat
    19441 gatgcaggaa aagatttttc cgataagtta tttcaagctg gattgcctgt tttactggat
    19501 ttacctgata acgaatctgg gaaagaaaaa atagattgga atgatatcct tagagaaaag
    19561 aaatcagatt tacaattgat acttgagtct gcaaaagaga cattgaggaa tcaaccagta
    19621 agacaaacct ctcaatgttt agaattgtga taacaaaatc aagatgtttt agctaatatt
    19681 agaatgaagg aggatagtat atgaccatta ttgaacgctt agaagaaaag gtcactaggc
    19741 aagaaagtaa ggtagcaaga gagacagaaa aactagctgc ttacaaagag caactggaga
    19801 cagcgatgtt tgcgacgttc aaaaggcgtc aaagcattag tcacatgagt tttgaagaag
    19861 ctcttgacca tgcctttggt aaagaaagac aattcgatga ttctgaattt agaaaggatg
    19921 aaatgagtga atgacaaaag attggaattt taatcaacca ttagaaagta aatcagaaaa
    19981 tcaagaagat ccagataaaa ttgcggcttt atttagaaat catcaaggag gtaatgatgt
    20041 aaattatgaa gcagcttttc aaaagcgtaa acaagcacct gtgacggaat caaattctag
    20101 ttctaaaccc aaagttacag aggttagaac aggaaaagag acagatatca ctacaagtta
    20161 tcagcaacat cttaaaagac tgattgcgga taacaatagc gatattgaaa gtagtcaaaa
    20221 gaaaattgaa gagctacata cgttgattga cacaaagaat aaagacaata agaaattgca
    20281 gtccatttat gatgcgattt cggaattaca ctaagcagtc taaagaggct gctttttttg
    20341 agaggttata gatgtttaca aaaattttta agaaaaatca agacaatagt gatatattta
    20401 agaagttgat tcatagacta tctgatatgt ctgtccaaga tcttgaaaaa attgacagat
    20461 tgttagatat cattttcact ccagaacaag aatcagaaca actaaaaaca gaaacaactt
    20521 atagggaaga aactttggac gacacattaa aaaaagctaa aaatcaactt cataaggaac
    20581 aattggagaa gaatttagag agatttagga aaaatagtca ataacgcacc aaaaatggtg
    20641 catttgcttt ttctaaatgt tataatggtg gtatcaaata aaaggagttt gccatgattg
    20701 gaaagaacat aaaatcctta cgtaaaacac atgacttaac acaacacgac tttgcacgga
    20761 tt
//
LOCUS       DAVBNZ010000036        20705 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000036 DAVBNZ010000000
VERSION     DAVBNZ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20705
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.036"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(37..1716)
                     /locus_tag="VQ860_001394"
     CDS             complement(37..1716)
                     /locus_tag="VQ860_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3119818.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     ICTGDFKFDFTPVGEPADLHRMAALGEDGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEILILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(1718..1951)
                     /locus_tag="VQ860_001395"
     CDS             complement(1718..1951)
                     /locus_tag="VQ860_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET3119819.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRIAARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFKITEF"
     gene            complement(2757..2909)
                     /gene="cibB"
                     /locus_tag="VQ860_001396"
     CDS             complement(2757..2909)
                     /gene="cibB"
                     /locus_tag="VQ860_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET3119820.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(2911..3096)
                     /gene="cibA"
                     /locus_tag="VQ860_001397"
     CDS             complement(2911..3096)
                     /gene="cibA"
                     /locus_tag="VQ860_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET3119821.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            3274..3957
                     /gene="tsaB"
                     /locus_tag="VQ860_001398"
     CDS             3274..3957
                     /gene="tsaB"
                     /locus_tag="VQ860_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET3119822.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQILAEMTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            3954..4391
                     /gene="rimI"
                     /locus_tag="VQ860_001399"
     CDS             3954..4391
                     /gene="rimI"
                     /locus_tag="VQ860_001399"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET3119823.1"
                     /translation="MIEIKRIQKHPDLAQAIYAVMIAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQSQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            4381..5391
                     /gene="tsaD"
                     /locus_tag="VQ860_001400"
     CDS             4381..5391
                     /gene="tsaD"
                     /locus_tag="VQ860_001400"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET3119824.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDDLAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(5431..6737)
                     /locus_tag="VQ860_001401"
                     /pseudo
     CDS             complement(5431..6737)
                     /locus_tag="VQ860_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(7071..7365)
                     /locus_tag="VQ860_001402"
                     /pseudo
     CDS             complement(7071..7365)
                     /locus_tag="VQ860_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7472..7765)
                     /locus_tag="VQ860_001403"
                     /pseudo
     CDS             complement(7472..7765)
                     /locus_tag="VQ860_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            8008..9212
                     /locus_tag="VQ860_001404"
                     /pseudo
     CDS             8008..9212
                     /locus_tag="VQ860_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            9205..10081
                     /locus_tag="VQ860_001405"
                     /pseudo
     CDS             9205..10081
                     /locus_tag="VQ860_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            10168..11784
                     /locus_tag="VQ860_001406"
     CDS             10168..11784
                     /locus_tag="VQ860_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119825.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            11804..12647
                     /locus_tag="VQ860_001407"
                     /pseudo
     CDS             11804..12647
                     /locus_tag="VQ860_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12715..14216
                     /locus_tag="VQ860_001408"
                     /pseudo
     CDS             12715..14216
                     /locus_tag="VQ860_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            14228..14977
                     /locus_tag="VQ860_001409"
     CDS             14228..14977
                     /locus_tag="VQ860_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET3119826.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            14990..16162
                     /locus_tag="VQ860_001410"
     CDS             14990..16162
                     /locus_tag="VQ860_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3119827.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRDLEAYKDKVYTRGIWIRD"
     gene            16557..17420
                     /locus_tag="VQ860_001411"
     CDS             16557..17420
                     /locus_tag="VQ860_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3119828.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            17706..17939
                     /locus_tag="VQ860_001412"
     CDS             17706..17939
                     /locus_tag="VQ860_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119829.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            17961..18638
                     /locus_tag="VQ860_001413"
     CDS             17961..18638
                     /locus_tag="VQ860_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3119830.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVNRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            18650..19315
                     /locus_tag="VQ860_001414"
     CDS             18650..19315
                     /locus_tag="VQ860_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3119831.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            19387..20613
                     /locus_tag="VQ860_001415"
     CDS             19387..20613
                     /locus_tag="VQ860_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3119832.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SAPIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         6477 a         3230 c         4185 g         6813 t
ORIGIN      
        1 atacggcaag gcgaagctga cgtggtttga agagtattat tcttcatctg gtgtgaggat
       61 catcgggatg atgatcggtt cacgttcggt attttcatag aggaaggggc gaatagcgtt
      121 gacaatggca ccattgacag attgcacgct agcatcctta tttttcagtg cgatacgaat
      181 ggcattgaag aggatacgct ggctttggcg aatcaagtcg ccagactctc tcatgtagac
      241 aaagcctcgg ctgaggatgt ctggaccaga tagaatcatc tgcgatttga agtcaacagt
      301 tgcgactgcc agaacgacac cgtcttcaga tagatcgcga cgatctttga ggacagctgc
      361 gccaatttca ccgatacgat ttccatcgac atagatatct tgggcgttga aatgacctgc
      421 gatacgagct gagtcagcag taagggcaag cacatcgcca ttgctcatga taaagatatt
      481 gtccttctca acaccagtat ccactgctag tccagcgtgg actttttgca tgcggtattc
      541 accgtggaca ggcatgaagt attttggctt aatcaagcgg agcatgagtt tttgctcttg
      601 ctgaccaccg tgtccagatg tatggatatt gttcacttta ccgtggataa cttcgacacc
      661 agcttcagaa ataatgttaa tcagcttgtt gacgctagta gtgtttccag ggatgggact
      721 agaagagaag ataacggtat cgcctggttg gagttgtacc tgacggtggg ttccgttggc
      781 gatacgagag agggctgcca taggttcacc ttgactacct gtacagagga tcagaatctc
      841 acctgcagga tagtctttga tttcatttgg ctcaataaag gttcccttag gagctttgat
      901 gtagccaaga tcgattccgt tgacaatggc cttttccata gagcgaccaa agaccgcaat
      961 cttgcgccca gtcttaacag cagcttccgt tgcttgttgg agacggaaga tatttgaggc
     1021 gaaggatgca aagatgatac gtccctcgat accttggata atcttcatga tggactggcc
     1081 gacaaccttt tcagagttgg taaaggttgg aacctcagca ttggtcgagt cagagagcaa
     1141 gcaaagcact ccatcttcac ctagggctgc catacggtgc aagtccgcag gttctccaac
     1201 tggagtaaag tcgaacttaa agtcacctgt acagatgatt ttcccttgag gagtatggat
     1261 gacaattccc aaaggttctg gaatagagtg agtcgttcta aagaaagttg ccttgagatt
     1321 tttaaaggtc aactcggtgt tgtggttgat ttcgtaaagt ttggcgttgc gcaagaggcc
     1381 gtgttcttcg agtttcccac ggatcaaagc caaggcaagc ggtccagcat aaatagggac
     1441 atttgcttgc ttgagtagga acggaatccc accaatgtgg tcctcgtgtc cgtgtgtgat
     1501 taaaacagcc ttgacgcggt cgatattgtc tacgatgtaa gagtagtcag gaatgacata
     1561 gtcgatacca agcaagtcat cttctgggaa tttaatccca gcatcgacga tgataatctc
     1621 gtcttggtat tcaattccgt aagtgttttt cccgatttct cctagaccac cgatggcaaa
     1681 aacgccgact tcttcaggtt taagagtgta ggccatatta gaactccgta attttgaagg
     1741 cgccagtttc tttttcgtaa tcgagcaatt tgtcagacaa gagttcgata tattcgatat
     1801 tgtactctgg gcgattttct tcgacaagtt ggcgagcagc gatacgaccc tcaagttctg
     1861 agctggcatc gatgtctagg taaagcgcgc gtgttgtttc acgacgtggg ctacgttctt
     1921 ttgtttcttg ataaaaaact ttgtaaatca tatagttcct ttctatttac aggtcagctt
     1981 attccaaact tttagcagag atttgcttga tttcattcca ttttgtgtct agattgacct
     2041 tgattcgtta caattatttc aattatacca caaaatgaaa aattagtaaa agacggaaac
     2101 gagaaagtta ggggacgatt tctttggtaa gcgtttgcaa aaacaaagaa aatgtattat
     2161 gttgataacg gaagtgaaat ttattgcttg tcataattcc atatagattt taagtcaagg
     2221 aggttgccct atgtataact tatttgcttt tgctatcgga gttcgtttgc tagcttttat
     2281 cgtttttgtt gcttgcgttt atggaggaaa tcttctattt gccaaactgg aacgatgaca
     2341 aaccaagttc ttgaggaaaa ttacctttgt gactctctac tcgctttttc tcctcctcgt
     2401 gacctatgtc gtttggtttg tattttactt tggattgccc tgcttatgct ggggtttttt
     2461 gtttggggat gtagagatag tagatttacg acacgaaaat tccaccccat ctatcaagat
     2521 gaggtggtct ttgcattttt ctaacatgac atgacaatgg aattttcaaa gcttattatt
     2581 tttatgggag tcattgttct gctcaaaaat agagttgaag cataaaaata aaacaataca
     2641 aacagataaa tcgaatggta aagggatagt agtaatgttc aaatcattga gaatgctgag
     2701 caaactgtaa gagatgaaga caataaaatt tatccttcta aaaatgtgtt tcttatctag
     2761 catgacttac caaacttttt acgaaggtct tttccaatgg tataacctgc cataaataaa
     2821 gcgataccaa cacctacacc aaagccaccc ttgatttctt gcaattcctt attagaaatt
     2881 tcacgatagt tgttcaaatt tttcatcata ttaatctcct cctaaaaaat aaccagctgc
     2941 caaaccagaa cctataagtg ctgttccacc tgcaatagct ttccaagata ctgctactcc
     3001 aaagataacc aagggagcga gaccgccatc aatatctgat aattcatttt cagataagga
     3061 taaaaattga ttgtcaagaa tgtcaaaatt tgtcattgaa ttttcctcct tttttcttgt
     3121 tcacttttat attcggaaaa gaaaaggaaa agtgagcatt tttttaaatt atttttagtt
     3181 aagtgagggc actcttgtct gggggcaaag aaaattccca tgtgccagct tttgtagtat
     3241 aatagtaagc agacaaaaag ataggaatgt gttatgaaag tattagcttt tgatacgtcc
     3301 agcaaggctc tttctctcgc tattttagag gataagcaga ttcttgccga gatgacgatt
     3361 aatattaaga aaaatcacag tattaccctc atgcctgcca tcgatttttt gatggcaagt
     3421 ttggactgga cacccaagga tttggaccga atcgtggtgg ctgaagggcc aggtagctac
     3481 acaggcttgc gaattgcggt agccactgcc aagactttgg ctcatactct gaacatcgag
     3541 ttagttggta tgtctagcct cttggctctg gtaccctacc aacaagaagg cttgttcgtc
     3601 tctttgatgg atgcgcgtcg caacaatgtt tatgcaggat tttatgaaaa tgctaaaccc
     3661 gtcatgccag aagctcactt accctttgag cgagtgattg agttaatcaa gggtgctagt
     3721 caggttacct ttgtcggaga agttggcccc tttgttgagc agattcaaga atacttgcca
     3781 aggactaatt tcaaagaaac cttgccaaat gcagctaatc tagctctatg ggcctgggac
     3841 aaggaagcag actccttgca tgattttgtg ccgaactacc tcaagcgtgt cgaagctgag
     3901 gaaaactggc tcaagaatca caccgagtct ggcgagtctt acattaaacg cttatgatag
     3961 aaatcaaacg aatccaaaaa catcctgact tggctcaagc catctacgct gttatgatag
     4021 ctgtttaccc agtcagtcct tggacgctgg aacaaatcca agcagacctg tcccaagacc
     4081 agacttggta tgctttggct tatgatgggg cagaagtgat tggatttcta gctgtgcagg
     4141 agaatctttt tgaagcagaa gtcctgcaaa tcgctgtcaa aggagcttat cagagtcagg
     4201 ggattgcgtc agccttgttt gctcaattgc cgacagacaa ggaaattttc ctcgaagtca
     4261 gacagtcaaa tcaacgagcg caagcatttt acaagaaaga aaagatggca gttatcgctg
     4321 agcgaaaggc ctactaccat gacccagtcg aggacgccat tatcatgaag agagaaatag
     4381 atgaaggata gatatatttt agcatttgag acatcctgtg atgagaccag tgtcgccgtc
     4441 ttgaaaaacg acgatgagct cttgtccaat gtcattgcta gtcaaattga gagtcacaaa
     4501 cgttttggtg gcgtagtgcc cgaagtagcc agtcgtcacc atgtcgaggt cattacagcc
     4561 tgtatcgagg aggcattggc agaagcaggg attaccgaag aggacgtgac agctgttgcg
     4621 gttacctacg gaccaggctt ggtcggagcc ttgctagttg gtttgtcagc tgccaaggcc
     4681 tttgcttggg ctcacggact tccactgatt cctgttaatc acatggctgg gcacctcatg
     4741 gcagctcaga gtgtggagcc tttggagttt cccttgctag cccttttagt cagtggtggg
     4801 cacacagagt tggtctatgt ttctgaggct ggcgattaca agattgttgg ggagacacga
     4861 gacgatgcag ttggggaggc ttatgacaag gtcggtcgtg tcatgggctt gacctatcct
     4921 gcaggtcgtg agattgacga tctggctcat caggggcagg atatttatga tttcccccgt
     4981 gccatgatta aggaagataa tctggagttc tccttctcag gtttgaaatc tgcctttatc
     5041 aatcttcatc acaatgccga gcaaaaggga gaaagcctgt ctacagaaga tttgtgtgct
     5101 tccttccaag cagcagttat ggacattctc atggcaaaaa ctaagaaggc tttggagaaa
     5161 tatcctgtta aaaccctagt tgtggcaggt ggtgtggcag ccaataaagg tctcagagaa
     5221 cgcctagcag ccgaaatcac agatgtcaag gttatcatcc cccctctgcg actctgcgga
     5281 gacaatgcag gtatgattgc ctatgccagc gtcagcgagt ggaacaaaga aaacttcgca
     5341 ggctgggacc tcaatgccaa accaagtctt gcctttgata ccatggaata aagagtggct
     5401 ctttgtcaag tgtagtgggt aggcgaaaag ctacaatctg gagagtacga aattcgtact
     5461 ctcttttttg atgttcaaag tcatcaaaat ccgtttttta aaattgttaa agttccggaa
     5521 accaaaggct ttgcgcttga taaccttaat caaattattg gtcgcttcaa gtttagcgtt
     5581 ggaataaggc agcttaagtg cgttgataat cttatctcta tcccttaaaa aagtccaaaa
     5641 gaccgtttga aaaagcggat gaaccgttgg cagttcttgc tcaatcaatc caaagaaatg
     5701 gtcggcattc ttctcttgaa aatgaaagag caggagttga tagagttcgt agtgaacctg
     5761 taatccctca gagtaagaaa gcagcttatc tcgtacttcc cgatgggtta agtgcattcg
     5821 aaacgtgggc tgatagaatc gtttctgaca gagcttgaag ctatcctggt gtagtaaatc
     5881 agtccagtgg actgatttag cccgagccta gaaacgaaaa agcgagggtt ccaaaagcgc
     5941 ttgagcgccc gatactccaa ggattttcgg tcaaattggt tcatgatttg gattcgtact
     6001 cggttcatag ctcggctcag atgttggaca atgtggaagc ggtcaagaac aatcttcgcc
     6061 tttggaaaga gttgcttagc gagccgataa taagggctgt acatgtccat ggtgatgacc
     6121 tcgaccagct cccgaacctc tctctgatag cgttggaaat ggtttcgaat caccgcatga
     6181 gttcgtccgt ctaaaattgc gaggatggat ttggactcaa aatcttgggc aatgaagctc
     6241 attttgctct ttttgaagct atactcatcc caactcataa cttttggcaa cttggtccaa
     6301 tcggtttcaa acttaaattc cctcagtttt cggatgacgg tggaagttga gcccgccaat
     6361 ctgtgggcaa tctcagtcat agactgcttt tcaaggagga gctgagcgat tttttgtctc
     6421 accatgttgg aaatctggca atttttcttg acaatggatg tttgagaaac gaccacctta
     6481 aggcaattct tgcactgaaa gcggcgcttt ttgagatgca gtaccgtggg taaaccctga
     6541 cagtcgagaa gcggaatttt agaggctttc tggaagtcgt atttgatcat cttcccttga
     6601 caatgaggac aaggaggagc gggggaatcc aactttgcct gaacgactag atgggtttgg
     6661 tatttcagaa cagacaagat tttgatattt ttgtcttcca atccgagcaa atctgtggta
     6721 ttcttaagtt gttccatatg aaccctttct aatgagttgg ttagacgctt ttcattatag
     6781 gtcatatggg gctttttttc tacaagaaac gaccctataa ttcctggggt gggattaccc
     6841 actacagaaa ttatagagcc aaagcattcc aaagtcttgt ctgactctgg aatgttttct
     6901 gttcacagtt gttttgtaac tgcctaataa gtaaccgcgc tataacgagg tatctaccga
     6961 gattgtcaat tctccagtat actgttataa aaaacaaaac tggaggattt ttttatgtcc
     7021 cccccatcgt cccatcgact gttccgtagc tgcccaataa cggagtataa tcagctgaaa
     7081 caagaatagg acaaaagtgc ctcaagaaaa gcatcgtaat ttgacaatat tattctgaga
     7141 tgtttttgat gtaagcccat attttctcaa tgggattata ctcgggtgaa taggtaggaa
     7201 gtggtaacag tctatgccct gctccttaca catgttcatt ctgtgaaacc ttgcattgtc
     7261 cataatgata agggatggtg tatctaaagt aggtagtaag aatttttgga agcaagcttc
     7321 gaaaaagtca ctcgtcatcg tatctttata ggtcatcgga gccatagtat attgaaacaa
     7381 aaaagggcat tagtacttct ataacagtat cgcaatctct ggtgtgcgtt gtctcgatct
     7441 taattcaaat aattatatct tcttccagag agactaactg cctgctcaag gctcgatcat
     7501 attcgagata aaaataggtc tcaacccctg tctcataaat ataaatagga gtcaggtagc
     7561 ttaagtgatt caattcttta aggaaccgat ttactttttc tgggtcttgt tcgcagtagg
     7621 tacggctctt ttttagacta tatcccatag cctttagagc gtaatgaata gttgttggag
     7681 gacagttgaa ttcagcagct atttcagtca aataagcatc gggatgagtt tcaatataga
     7741 tttttaattt atctctatca attttttcaa ttaatagtgg aagttttttt gaagttagtg
     7801 tattgaaacg tttttataca gtgctaaaat ttgaagtgta gtgcagatgt atttgtaata
     7861 gtattatagc aattctttgg agaaggtcga gacaagataa aataggtatc tttgagatat
     7921 aagcatgatt tactataaaa ttattgagtt attcataaaa atttctctat caaatatcat
     7981 aatgcgtcgt ttaaggagat ggttacaatg caatatagtt gtggaaaaat aaatattaat
     8041 atccctgatg gatatggaga cattaaggat atagtgtttt cggctcatat tatagttagg
     8101 tataataatg gacattgtgg aggtatagat ccgcatataa ttggactttg taaaaagcag
     8161 atcagaagga tgtctctata tcctattttg ataatcgtat ctagagattc aaaggttatt
     8221 gatgattata aaaatttaga tattgcctat gttgattgta ctcaatgttc aaataatttt
     8281 gaaactgcct tacacgttaa aaatatttta aaattattaa aaatccaact tatacactgt
     8341 catggctact caactaatta ttttttatat atgttaaaaa aacttgacaa gaatggattt
     8401 ggaaaggtta agacagtgat aacatgccat ggatgggttg aatataactt aaaaaagaaa
     8461 ttcttgactt attttgattt ttggacatat tctatgggag atgcttttat ttgtgtatct
     8521 gaaactatga aaaaaagatt ggagagtata ataaaaaaat aagaagatag ttgcaataaa
     8581 taacggaatt aatgtatcaa atagcgattt agatgtagta ggtgttcaag actttaaaaa
     8641 agaattttgt attccaaata acaaaaaatc atttgttatg ttggaaggtt ggatccagaa
     8701 aaaaggccgg atagattcct tgaatttgca gaaaaattat ttttagtcag agaagatgtg
     8761 atttttatta tggctggaaa tggtagtatg tgggctgctt tgaaagaaaa aatttgctat
     8821 ttgaaatgta gagataattt caggttactt ggtgaaatct atccagtact atagtttacc
     8881 aaatatcgga tttattgtat attccttctg atacagaagg aatatctatg tgtgttttag
     8941 agtcaatgtc acaaggaact ccggttttag ctagtaatgt tggcgggtta agtgaaatta
     9001 ttgaacatag ggttgatgga tttttatttg agaaggaaga tgttgaggga gtgtgtgctt
     9061 gtgctaattt tttactcaat gattctgagt atttgaaata tgtaggtgag aatagtaaat
     9121 caaaaataag aaaacatttt tctgtgcaaa aaatgtttgt agaaaccatg agagtatatg
     9181 atgaattatt agagaagagt agtcatggat aggaatatag atcaagaatt agtaagtatt
     9241 ataataccaa cacataatag gtatgaatct ctgattagag ctgtgaaaag ttgtttacat
     9301 caaagttata aaaatatcga agttataatt attgatgata attatagtaa tgtaaattta
     9361 agaaataaaa ttatccatca atttggctat accaatcata gaattaagtt aattttaagt
     9421 aatgaagatt taggtgcaac taatgccaga aacataggta tcaaaaattc tagaggtaag
     9481 tatatatcat ttttagacga tgatgatgaa tatatgccag atcgaatttt aaagttgatg
     9541 gcttgtttta aaaagagtag aatgaagaat ttagctttag tttatagtta tggaataata
     9601 atttatccaa atggtacacg agaagaggag aagaccgatt ttgttggaaa tcccttgttt
     9661 gttcaaatgg ttcacaatat agcaggtacg tcattttggt tgtgtaaaaa agaggtgcta
     9721 gaattaatta atggttttga gaaaatagat tcacatcagg acggtgttgt tttattaaaa
     9781 ctacttgctc aaggatacca aattgatata gtgcgagaat tcttggtgaa ttactacgct
     9841 cacagtaaag aaaacggtat cactggagtg acacaaaaaa caattaatgc agatgaagaa
     9901 tattataatt actgtaggaa atattttaat ttattgagtt tcaacgagag aatattggtt
     9961 acaaagaaat attattcttt aaacataaag cggttactat ttaataggag acaaatgcaa
    10021 ggctttaaaa gtaatcaaga aggcaagaga agaaaaaatt tttaacgaat ttctttttta
    10081 aaatatatgt tattatatca ttttggtttt ttctattgta tatatgacaa ctatgttcaa
    10141 ttaaaattta gaaagtgaga aactattgtg tatactatta taaaatcaaa tataaaaaaa
    10201 tttagtttat taacgatatt tattgttgct ggtcaattat tgctaattta tgcagcaact
    10261 attaatgctc tggtgttgaa tgaattaatt gcgatgaatt tagagcggtt tttgaaattg
    10321 tcaatctacc aaatgattgt ctggtgtggg ataatattcc ttgactgggt agtgaaaaat
    10381 tatcaggttg aagtgatcca agagtttaat ctagagattc gaaatagagt tgccacagac
    10441 atctctaact ctacctatca agaatttcat agtaaatcat caggaacata tctttcgtgg
    10501 ctaaataatg atgttcagac tttaaatgat caggctttta aacaactttt tttagtaata
    10561 aaaggaattt ctggtactat atttgcagtt gtgactctta atcactatca ttggtcattg
    10621 actgtagcca ccttgttttc attaatgatt atgctacttg taccaaaaat ctttgcatcg
    10681 aaaatgcgag aagttagtct aaatttaact aaccaaaatg aagctttttt aaaatctagt
    10741 gagactatat tgaatggatt tgatgtgtta gcgtccttga atcttttata tgtattgcct
    10801 aagaaaatta aagaagcagg aattttatta aagatggtta tacaaagaaa gacaactgta
    10861 gaaacgttag caggcgctat tagcttcttt ctcaatattt tttttcagat atctctcgtt
    10921 tttttaacag gctatcttgc aataaaagga atagtgaaaa ttggtactat tgaagcaata
    10981 ggagcactaa caggtgttat ttttacagcg ctaggtgaat taggaggtca attatcctct
    11041 attattggta cgaagcctat ttttttaaaa ttgtattcaa ttaatccaat tgagtcaaat
    11101 aaaatgaatg atatcgaacc aaatgaggtg aatagagatt ttccgttata tgaagcaaaa
    11161 aatatttgct ataagtatgg agataaagaa atattaaaaa acttaaattt ttgttttcaa
    11221 cgtaatgaaa agtatttaat tttaggtgaa agtggaagcg ggaaatctac attattaaaa
    11281 ttattgaatg gctttttgag agattatagt ggagaattgc gattctgcgg ggatgatata
    11341 aaaaaaacct cctatttaaa tatggtttcg aatgttctat atgtagatca aaaagcttat
    11401 ttgtttgaag gtacgattag agataatatt ttattggaag aaaattatac tgatgaagaa
    11461 atactacagt ctttagagca agttggtttg agtgtaaaag attttcctaa taacatttta
    11521 gattattatg ttggtgatga tgggagatta ctgtcaggag ggcagaaaca aaaaattact
    11581 ttagctagag ggctaattag aaataagaaa atagtattaa ttgacgaggg aacttctgct
    11641 atcgatagga gaacttcgtt agcgattgaa cgtaagatat tagatagaga ggatttgact
    11701 gtcattattg ttacccatgc tccgcatccg gaacttaaac aatattttac taagatatat
    11761 caatttccaa aggattttat ttaagaatat aggggaggga aacatgagat tctattgtga
    11821 agcttatgag gtaattactg aagagaaaaa agtatacttt aatgatattg agttagaagt
    11881 taagtattcc tctgtcgaag aattgtttat aatatgtgag aaattattag ataagaaaaa
    11941 agtatcattt ttttatgtat atgagaaacc cttaaggtat ctgttatttg actatatatt
    12001 tctactagtt ctagctaaaa aaatatccca atcttagatg gagtttccaa taagcaagtt
    12061 gatccaacgt tgctgcatca cttttctttg gaaattgaaa agaattttat cgatttttgc
    12121 tataaaaata tggatctcat cctaaaaact caaagtatat ctttgtgtca tagagaagag
    12181 cttattattg tagatgtttc agatgactct aaatttggtg ttttttacaa gcgttttaga
    12241 acactggttg ataaaaataa cggaaaatat gtttgtgttt ataatttcag tcgtgtttca
    12301 gatatactgc aaaactggaa aaattattgc aatcgaaaat tttcggttac gtttactgaa
    12361 agccaatttg aattatttaa gcttttatat aatcaaaaaa attttaaaac aatttcgttg
    12421 ctatttggaa aaaaattgtt gctggaggaa ttatctatta tagcgatctt actaatatag
    12481 aatacttttg tattttttgg tgggatagta tgtttgggaa agattctatt ggaaaatacg
    12541 tatatgtaga agagattagt agatgtcatt ttttagatag aaattattct ttttgttatg
    12601 gtttacaaga ttataaaagt aaacttatta aatatttttt agaatagtta atctattcga
    12661 gagagataaa gaaatatgga aaatacttta ttgaatatca caggaagctt cgatatggaa
    12721 actaggaatc taattagtta ttctttaact gatatctttg aaacagataa aataagaatt
    12781 gaacttcttg gagaaattta ttataaaaat ataaagttgg aattgcatga attcgctgga
    12841 ttgtataaga tttatggaat tagcttaata aagaatatta ccggaatgtt tttaattata
    12901 atttttgata cgaagacaaa agaattaaaa atttttcaag atataacgac ttcatacttt
    12961 aatttatact atactgttta tggaggtgtg ttctatatat agtacatctt taaagaaagt
    13021 gatgaagtta tctcatgttc ccgttacctt aaataacaaa aaaatacaag aatttatgag
    13081 aaatggattt attttagatt caaatacttt agtaaccgaa attaataaat tagaatattt
    13141 ctcttacatt tctgtaaata atactcttcg tatatgtggt attgattata atgattcaaa
    13201 caattttact aaagaacaag tattaaagaa ttgggactct atgctacgtg aatctatatt
    13261 aagagtgtat agtgaagcag gagaggctaa tattacacta tcatctggtt ttgattcaaa
    13321 ttatatatta tatacattag cgaattatac gaattcttca attaatgcat tttgcatagg
    13381 aggagaaaaa ggaattaatg agattcctga agtaactaaa attgcaaaat tttatggtat
    13441 aaatttatta gttgatactg taatgagccc aagatttaga atattttccc gatatagtat
    13501 ggagattgga aggaagtctc tttgaatgtg gtgtcatact gcagtactat ttaggcaggt
    13561 tgttgttcca aaaagggaac acaagtattc tttgtggcga gtcagcggat gaaataatga
    13621 cttttaagta tcattctgtg aactacaatc aattttgtaa tgataaacag aagtcagtat
    13681 attttagtta ttccgactat ccattttatg ttacaaattc aattgtttta aagaaaaata
    13741 gcctactttt gcatagtttt ggcattcatc ctagatatcc atataaaatg tctgagattg
    13801 ttgaaatgtc taaaaaaata tcagatctaa acgataaaaa agaatttcac aaaaagaact
    13861 gtgagttgag gtttcaagat agtgttcttg ataacataaa tagtgtcccg ggtacaactc
    13921 atttatttag ttgtttaaat attcaaacat tagtaaaaat tattttatat atttttcgat
    13981 acaacagttg tatgaaaata tttaatttta gagataaaga gcttatcttt tttaataaga
    14041 ttgtaaatgg gctgatacaa aatattgagg agaatttaga ggatgatatt gaaaggatat
    14101 tgaaatattt atatatatgt ttatttaacg aaatattcat tattaagaat aaggtgaatt
    14161 tttttgatga tgtggaattt aatcagacac ttagtgagtt tttagataaa ttgtagaggg
    14221 aatggttatg agtgacaata ctaagtatat ctttttatct ccacatttag atgacgcaat
    14281 tttttcctgt ggtgattata tttcaaaatt aacttcagaa ggagaaattg tacttgttat
    14341 tactatattt tctggttacc ctttgagcca acagctacag ccctctgcta agcaatttca
    14401 taagttgtgt aaccttggga aatatccgat tgaagaaagg aagaaagaag acaggttagc
    14461 ttgtgaacgt ctacaatgtg attttagaca cttatcgtac tatgaatgtc tctataggaa
    14521 agatagaaat ggcaattttc tataccgtca tatctatagt aaattaaaaa atgaggacac
    14581 attaaagaat gatatcataa aagagctgtt aatgcattta gacgacaaat gtgtcgtata
    14641 ttgtccgctt tcacttggtg accatgttga tcatgttttt gtgaatagta ttggaagggc
    14701 gcttgaattt atgcgttata aagtaatata ttatgaggac ttcccatatg taagtgatag
    14761 tagtatggtt agttatatgg gaaaaactaa agaattaaaa atgtatcaag aggaacttga
    14821 tgaaaaacat tatattgata gaatatcatc aatattgtgc tataaatctc agattttgat
    14881 aatctggaaa tcagttgaaa aacttttaaa caatattaaa gagttgtatt taaggaatgg
    14941 ggcagcttat tctattagat tttggattaa gaaataagga agtagtttta tgaatatagc
    15001 agtaattggt ttggggcatg ttgggctggc ctacgcgtta ctatttgcat ctaaatataa
    15061 agttgttgca tatgatatag attctgtaaa aataaataat ttaaaaaagg gcactcttcc
    15121 atctaaaaat gaagagctta tgaagttttt ttgcgagaat aacttaaata ttactttttt
    15181 tgatacattt tctgaaatta aaaataatat tgattattat attattgcgc ttccgacaga
    15241 ttatgatgag aaaattggta gttttaatac atatgaaatc gaacaaacgg tatcgaagat
    15301 tctgagggta aaacctaatg gaaagattat tttaaagtca acagttccga tcggcttttc
    15361 aaacaaatta aaaaggctgt ttgatacaaa aaatatcatt tttgtccctg aatttttgag
    15421 agaaggttgt tctatatatg ataatttata tccaagtcgc atagttgttg gagatgagac
    15481 agttgaagga agaaaaattg cagagttgtt cctttcgatt agtactcata gtactgccaa
    15541 tattaaaaat gttatgttag tttctcctac tgaagcagaa gcaattaagc ttttttctaa
    15601 cacattctta gctctccgtg ttgctttttt taatgaacta gattcttttg ctgagaggag
    15661 aagtttaaat gctgaagttg taataaaagg tgtttgttta gatccaagaa ttggaaattt
    15721 ttataataat ccttcttttg gatttggagg atattgtctt cccaaagata ctaaacaatt
    15781 aaaaaaagaa tttatagaaa taaatgcccc agtgatagaa gcgattgata tttcaaacac
    15841 aaatagaaaa cagttcatag ttaaacaaat attggaacga aagccaaaga tagtaggaat
    15901 atataaattg gggatgaaat ataattcaga taattacaaa gagtcagcta ttttaagtat
    15961 aattaatgaa ctattgattg tcggtataaa aattttagta tatgaaccaa atttaaacgt
    16021 tagtatagat aacgtaattt ttgaaaagaa ttttgaacta tttataaaac aaagtgatct
    16081 aattgttgca aatagatggg atagggacct tgaagcttat aaagataaag tttacacaag
    16141 ggggatctgg ataagagatt aactattgat attaaaaagg caataattta taaaatttgt
    16201 acaaaaaaat gttaaatttt cacattttca tagtatactg tttaatagaa agtaggttct
    16261 ttgtaaccgc tccattataa aatcctttca ctcttccggt atactattag gaaaaacata
    16321 actggaggat attttgagct cacacctcat cgttccagtg gctgttcccc aagctcgtgt
    16381 actgcccaaa aaagttagac attctattta gaacgaggat tgagttctgt attgtacaag
    16441 gctcggtcct tttagagtca gcttaaggct ggctttttca atcaccaaag tgtcagaatg
    16501 ttttgacaaa tgaacacaaa taatgatata atatgcaaaa gctaggaggt ggtaggatga
    16561 ttgaaaaaat ggaactgggg gaattttaca aggaattgcg cttggcgaga aagctcaagc
    16621 agtcagatgt ggcttgtgct ggactaacag cctctcagtt gtccaagttt gaactaggac
    16681 agtctatgct gtctgcagac aagctgatcc tagccatcca agggatcaat atgaattttg
    16741 atgagtttgg gcacaaactc aacaactatc aagaatctcc acatatgcga attggtagaa
    16801 gggttgtgga ttgcttttcc catcaggata tagctgcttt agagcagcta ttggaggaag
    16861 tcgatcaaga acagatggcg cagacctatc gtcgtttgaa tgccattgtg attaaaaatg
    16921 cactccattc cttagataaa agctacccgc taacagagga ggatagcgag tttttgacta
    16981 cctacctcta cgctattgag tcttggacct ggtttgaact ctatcttttt tgcaatacta
    17041 tgcccttctt gagcaatcaa gatctgatct ttttatcaac ctccttactc gaaaaatcca
    17101 aggaatttaa agagttagta cacaatcgat ggtatatgaa aagtggttat cttaatatca
    17161 tctcagaact tatggagcgc aagctatttt cttatattcc aatctttgaa gctgagctgg
    17221 agcgcatgct ccgtccatac gatgtttttg aaaaagtatt gtggcagttt ttaaagaaaa
    17281 tgcagatttt tcttcaaacc aaaggaagca atcaaaaaga gattgaacac tttatccaat
    17341 ctctgcaagt attagaaaat ccacaattga cagccctttt tgaattgcgt ttgcagcaat
    17401 acaaagagct tatcgattag ttagaaatgg gaaaaagata ataatatcag caacgatcgt
    17461 caataatgtt aaaacttgtt tcttcatatt acttccctcc tcattagtaa taactttatt
    17521 ataccaggga aataatcaaa tctaccaaaa tcgcaaatct gaaatttcta taagaaaaaa
    17581 tatcaaatat gcgattttct aaaataagcc aatttccgtg ttatactgtc cttgtaaaac
    17641 atttgaagca aatcctaggt cgcagaagtg gtttacaaat gaagataatt gaaggagtgt
    17701 aaaagatgtt aaatttacaa tttgcagaaa caatggaatt gacagaagct gagttgcaag
    17761 atgttagagg aggcaacctc gtaaattcta tgggaggtgg tggaagaagt ggtatatctg
    17821 gttggggcgt cccaggaatt taccctggtt ggggcaatca agggatgagt cctaatcgtg
    17881 gagcttttga ttggactata gatttagcag atggattgtt tggccgccgt agaagatagg
    17941 ctcttatagg agataatagg atgaagaaaa tgaaagaagt gaaatttcac ctagcaactg
    18001 gcttgttgat tttgacttat tacctcattt ttaatgtcac atcagactta gattttatgg
    18061 ttgctttgtc tgataatatg tactatgtgt tccaagtttt attggtactt attctgggaa
    18121 ctatagctac aattgctttt gtcaaaagtg aacattggaa agagtgtggt cgtttccagt
    18181 ttcgttggtc ttacctgggt gttttccttc tttctttttt cttattgttc gtgtgggcaa
    18241 atctaacaac ctatatcttt cctcgtaccc agaatggaag tacagtcgta gaagtagcca
    18301 ccagtttaac aggaattagc tattttgtta cgcgaatact ttatactagt attatcgcac
    18361 ctgtatcaga agaggttgtt tgtcgtggtc ttttgatgac aagtttatct aaagttaata
    18421 gatactatct tgatgttctt gtttccgctg ccatatttgg cgctatgcat gttttgcagt
    18481 atggttggat aacgacagat ttcataaagt attttggaat gggcttgata ttttgtatga
    18541 tgtttcgcta cacccgatcc atctattggg ctatagctct gcatgcttca tggaatagct
    18601 tcttactcat tgttacttta ttggtatttg gatattagaa aggtgatata tgaaaaagat
    18661 aatctcacac cgctacttta ttatagtttt tctactagtt attgctgacc agaagttcag
    18721 tgttttagtt ttacgcagcg accttgttgc tgggctatct gactttgcct attatctgtc
    18781 ggatatgatg ttgaattttc ttgtggtttt atttgctctt attgctatga tttggtcggg
    18841 gaaatggcag aaaatcaata gtagaaagtt taaaggatcc tatcttttct attccttcct
    18901 agctctgctt gcttttgttg cttggaattt tgtcaccttt tttcttttcc cacctactcg
    18961 aaatgaaatt tcttatcaac atgctgctcc tacttttaca ggagctacgg catttttgat
    19021 gtattttttt tatcctgtga ttgcaggtcc catttttgaa gacatgattt atcgtggatt
    19081 agtgatgact gctctggaaa aaggaaagaa atgggggcta gatgtacttg gttccgctgt
    19141 tttatttggg gtctcgcaca ttagtaatca cggttgggtc ttgacagact ttgtcttcta
    19201 tatgggtgga ggtcttatat ttgcagtctt atttagaatg acaaagtcaa tttattggcc
    19261 tattggactg catatagtct acaatggtat tggtcagctt ttgatgttac tgtaattttg
    19321 gttgttagta gtatcgcggt ctattcttgg ggaaagattc ccatttgaat ttaaaaagga
    19381 gttgtaatga aagtatttct tcaaaataga gattttaggc aattaactat caaccagtgg
    19441 atttcaacgc ttggggatac gattttttat ctggccttcc tgaattatgt ggcagatgcg
    19501 tcttttgccc ctttggcgat tttacttatc acgatttcag aaacccttcc ccaagttcta
    19561 caaatctttc tgggagtttt ggcggatttt caacatcatc gtgtcttgaa atacacagtc
    19621 attagtttta caaaattttt gctttactct atagtgtccc tatcgctttc agggcagtct
    19681 ttttccttgt tgctagtaac ctttatttgt ctgattaacc tcttgtctga cacattgagt
    19741 tatttttcag gcgccatgct cactccgatt ttcattagaa ttattgggca agatcatctg
    19801 gcagaagcta ttggatttaa acagtcaact gttagtttag tgaaaacaat cagtaatatc
    19861 ctaggaggag tcttactagg tattctatcc atccagttta tttccttact gaacgctctt
    19921 acctttttaa tcgcattttt aggtatcctc ttcataaaaa ctgacctctt gaaagtagaa
    19981 aaaacgatta gctatcaaga aggactctct gtaaaatcct tttgccagca tttgctccaa
    20041 tcatcgaaat tgatatggaa tatgaataag gtgctcttgg ttttgtttat tatctctact
    20101 agtcaagcag tgataaatgt tacagttcct gtctctactc tatttttgag gaatcaaccc
    20161 tttttgaatt tacaaacagg tcaatctctt gccttgctat ccacttttga actgtcagcc
    20221 ccgattgtcg gaagccttgt aagtggctat ctgcaacata ccatttccat aaaaacagct
    20281 ctctatgcct cacttgtcat ccagttgctt cttctagtag gatttgccac agttcgtttt
    20341 gactggattc tcatctttag taccttggat gcctttttcg caggtgttct ctctcctaga
    20401 ttgcaagaac tcgtctttaa acaaatacct gaggagtcaa tgggagcagt tcaatcttct
    20461 atcagtgcca ttacggttgt tttacctagc ttatttacaa tatctttggt aaccattgct
    20521 actagctttg gaactctggc agttagcttt gttttattgc tatttcttct agttgccttt
    20581 gttatgcttc tgaatattcg tgaaagtatt tagtggagaa tttctataat atatgtttga
    20641 gactggattg ccagtctttt tatgatggtc aaaatcaaca gacttttttc tcttttctga
    20701 atgtg
//
LOCUS       DAVBNZ010000037        20669 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000037 DAVBNZ010000000
VERSION     DAVBNZ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20669
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.037"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            173..2155
                     /locus_tag="VQ860_001416"
     CDS             173..2155
                     /locus_tag="VQ860_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3119833.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2456..7759
                     /locus_tag="VQ860_001417"
     CDS             2456..7759
                     /locus_tag="VQ860_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET3119834.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWKTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKAIITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGNMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIETLKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALTKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(7926..10085)
                     /locus_tag="VQ860_001418"
     CDS             complement(7926..10085)
                     /locus_tag="VQ860_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HET3119835.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQSAQP"
     gene            complement(10082..10678)
                     /gene="recU"
                     /locus_tag="VQ860_001419"
     CDS             complement(10082..10678)
                     /gene="recU"
                     /locus_tag="VQ860_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET3119836.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKRQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10744..11271
                     /locus_tag="VQ860_001420"
     CDS             10744..11271
                     /locus_tag="VQ860_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET3119837.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            11341..11670
                     /gene="gpsB"
                     /locus_tag="VQ860_001421"
     CDS             11341..11670
                     /gene="gpsB"
                     /locus_tag="VQ860_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET3119838.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTLKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11691..12071
                     /gene="rnpB"
                     /locus_tag="VQ860_001422"
     ncRNA           11691..12071
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ860_001422"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12156..13313
                     /locus_tag="VQ860_001423"
     CDS             12156..13313
                     /locus_tag="VQ860_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET3119839.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13326..14720
                     /gene="mapZ"
                     /locus_tag="VQ860_001424"
     CDS             13326..14720
                     /gene="mapZ"
                     /locus_tag="VQ860_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET3119840.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14796..16220
                     /gene="gndA"
                     /locus_tag="VQ860_001425"
     CDS             14796..16220
                     /gene="gndA"
                     /locus_tag="VQ860_001425"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET3119841.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16232..16921
                     /locus_tag="VQ860_001426"
     CDS             16232..16921
                     /locus_tag="VQ860_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3119842.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17019..18038
                     /gene="cbpC"
                     /locus_tag="VQ860_001427"
     CDS             17019..18038
                     /gene="cbpC"
                     /locus_tag="VQ860_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET3119843.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPISEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(18156..19388)
                     /locus_tag="VQ860_001428"
     CDS             complement(18156..19388)
                     /locus_tag="VQ860_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3119844.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLKLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(19548..20018)
                     /locus_tag="VQ860_001429"
     CDS             complement(19548..20018)
                     /locus_tag="VQ860_001429"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119845.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(20185..20595)
                     /locus_tag="VQ860_001430"
     CDS             complement(20185..20595)
                     /locus_tag="VQ860_001430"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119846.1"
                     /translation="MQLLELSHTQGQLTDEQLFWLQCLLNLSQTNNLVKIKKIEEHKY
                     DYKTECNSVLRFLLDKTVNSEGRITSSTEFGNFVSNLSFQHGIAGLLFPLNKLYHPEL
                     DSKILSIIKKAVTIRTSHTYEYQYSLLFGGAGYL"
BASE COUNT         6425 a         3742 c         4634 g         5868 t
ORIGIN      
        1 tgagttctct agtctggaga tttttcaata gacttcgtta ttgggcggtt acgatattca
       61 tattttttgc aaagatgttg tttgaaaaat aattttcaaa aattctgaaa attctgttga
      121 catctttctg aaaagagtct ataatggaga gaaagtttta aaggagaaaa tgatgaaaag
      181 ttcaaaacta tttgcccttg cgggcgtgac attattggcg gcgactactt tagctgcatg
      241 ctctggatca ggttcaagta ctaaaggtga gaagacattc tcatacattt atgagacaga
      301 ccctgataac ctcaactatt tgacaactgc taaggctgcg acagcaaata ttaccagtaa
      361 cgtggttgat ggtttgctag aaaatgatcg ctacgggaac tttgtgccgt ctatggctga
      421 ggattggtct gtatccaagg atggattgac ttacacttat actatccgta aggatgcaaa
      481 atggtatact tctgaaggtg aagaatacgc ggcagtcaaa gctcaagact ttgtaacagg
      541 actaaaatat gctgctgata aaaaatcaga tgctctttac cttgttcaag aatcaatcaa
      601 agggttggat gcctatgtaa aaggggaaat caaagatttc tcacaagtag gaattaaggc
      661 tctggatgaa cagacagttc agtacacttt gaacaaacca gaaagcttct ggaattctaa
      721 gacaaccatg ggtgtgcttg cgccagttaa tgaagagttt ttgaattcaa aaggagatga
      781 ttttgccaaa gctacggatc caagtagtct cttgtataac ggtccttatt tgttgaaatc
      841 cattgtgacc aaatcctctg ttgaatttgc gaaaaatccg aactactggg ataaggacaa
      901 tgtgcatgtt gacaaagtta aattgtcatt ctgggatggt caagatacca gcaaacctgc
      961 agaaaacttt aaagatggta gccttacagc agctcgtctc tatccaacaa gtgcaagttt
     1021 cgcagagctt gagaagagta tgaaggacaa tattgtctat actcaacaag actctattac
     1081 gtatctagtt ggtacaaata ttgaccgtca gtcctataaa tacacatcta agaccagcga
     1141 cgaacaaaag gcatcgacta aaaaggctct cttaaacaag gatttccgtc aggctattgc
     1201 ctttggattt gaccgtacag cctatgcctc tcagttgaat ggacaaactg gagcaagtaa
     1261 aatcttgcgt aatctctttg tgccaccaac atttgttcaa gcagatggta aaaactttgg
     1321 cgatatggtc aaagagaaat tggtcactta tggggatgaa tggaaggatg ttaatcttgc
     1381 agattctcag gatggtcttt acaatccaga aaaagccaag gctgaatttg ctaaagctaa
     1441 atcagcctta caagcagaag gagtccaatt cccaattcat ttggatatgc cagttgacca
     1501 gacagcaact acaaaagttc agcgcgtcca atctatgaaa caatccttgg aagcaacttt
     1561 aggagctgat aatgtcatta ttgatatcca acaactacaa aaagacgaag taaacaatat
     1621 tacatatttt gctgaaaatg ctgctggcga agattgggat ttatcagata atgtcggttg
     1681 gggtccagac tttgccgatc catcaaccta ccttgatatc atcaaaccat ctgtaggaga
     1741 aagtactaaa acatatttag ggtttgactc aggggaagat aatgtagctg ctaaaaaagt
     1801 aggtctatat gactacgaaa aattggttac tgaggctggt gatgaggcta cagatgttgc
     1861 taaacgctat gataaatacg ctgcagccca agcttggttg acagatagtg ctttgattat
     1921 tccaactaca tctcgtacag ggcgtccaat cttgtctaag atggtaccat ttacaatacc
     1981 atttgcattg tcaggaaata aaggtacaag tgaaccagtc ttgtataaat acttggaact
     2041 tcaagacaag gcagtcactg tagatgaata ccaaaaagct caggaaaaat ggatgaaaga
     2101 aaaagaagag tctaataaaa aggctcaaga agatctcgca aaacatgtga aataactgtt
     2161 gcaaaatata agaaaggatt tagtatttct cttgaatgct gaatcctttt ttacatttgt
     2221 aaagaaagct tctaaatgta ctgaccccca aaagttggag cctctttttg tcagaataga
     2281 gaaaattttt gttaatttta cttgtttcct attgctttct cagttattat ttgttatatt
     2341 aaaagtataa ttatttttta tttatcaggg ttaagcattg cactttcaga ggaaggagta
     2401 ttttttaaaa aggaaatgta aacgcttgct aaaaaatgaa aggatttaga agtttatgaa
     2461 taaaggatta tttgaaaaac gttgtaaata tagtattcgg aaattttcat taggtgttgc
     2521 ttctgttatg attggagctg cattctttgg gacaagtccg gttcttgcag atagcgtgca
     2581 gtctggttcc acggcgaact taccagctga tttagctact gctcttgcaa cagcaaaaga
     2641 gaatgatgga cgtgattttg aagcgcctaa ggtgggagaa gaccaaggtt ctccagaagt
     2701 tacagatgga cctaagacag aagaagaact attagcactt gaaaaagaaa aaccggctga
     2761 agaaaaacca aaagaggata aacctgcagc tgctaaacct gaaacaccta agacggtaac
     2821 ccctgaatgg aaaacggtag agaaaaaaga acaaaaggga acagtcacta tccgagaaga
     2881 aaaaggtgtc cgctacaacc aactatcctc aactgctcaa aatgataacg caggtaaacc
     2941 agccctgttt gaaaagaagg gcttgaccgt tgatgccaat ggaaatgcaa ctgttgattt
     3001 aaccttcaaa gatgattctg aaaagggcaa atcacgcttt ggtgtcttct tgaaatttaa
     3061 agataccaat aataatgttt ttgtcggtta tgacaaggat ggctggttct gggagtataa
     3121 atctccaaca actagcactt ggtatagagg tagtcgtgtt gctgctcctg aaacaggatc
     3181 aacaaaccgt ctctctatca ctctcaagtc agacggtcag ctaaatgcca gcaataacga
     3241 tgtcaatctc tttgacacag tgactctacc agctgcggtc aatgaccatc ttaaaaatga
     3301 gaagaagatc cttctcaagg cgggctctta tgacgatgag cgaacagttg ttagcgttaa
     3361 aacggataac caagaggggg taaaaacaga ggatacccct gctgaaaaag aaacaggtcc
     3421 tgaagttgat gatagcaagg tgacttatga cacgattcag tctaaggtcc tcaaagcagt
     3481 gattgaccaa gccttccctc gtgtcaagga atacaccttg aatggacata ctttgccagg
     3541 acaggtgcaa cagttcaacc aagtctttat caataaccac cgaatcaccc ctgaagtcac
     3601 ttataagaaa atcaatgaga caacagcaga gtacttgatg aagcttcgcg atgatgctca
     3661 cttaatcaat gcggaaatga cagtacgctt gcaagttgtg gacaatcaat tgcactttga
     3721 tgtgaccaag attgtcaacc acaatcaagt cactccaggt caaaagattg atgacgaaag
     3781 aaaactactt tcttctatta gtttcctcgg caatgcttta gtctctgttt ctagtgatca
     3841 aactggtgct aagtttgatg gggcaaccat gtcaaacaat acgcatgtca gcggagatga
     3901 tcatatcgat gtaaccaatc caatgaagga tttggctaag ggttacatgt atggatttgt
     3961 ttctacagat aagcttgctg ctggtgtttg gagtaactct caaaacagct atggtggtgg
     4021 ttcgaatgac tggactcgtt tgacagctta taaagaaaca gtcggaaatg ccaactatgt
     4081 aggaatccac agctctgaat ggcaatggga aaaagcttat aagggcattg ttttcccaga
     4141 atacacgaag gaacttccaa gtgctaaggt tgttatcact gaagatgcca atgcagacaa
     4201 gaacgttgat tggcaagatg gtgccattgc ttatcgtagc attatgaaca atcctcaagg
     4261 ttgggaaaaa gttaaggata tcacagctta ccgtatcgcg atgaactttg gttctcaagc
     4321 acaaaaccca ttccttatga ccttggatgg tatcaagaaa atcaatctcc atacagatgg
     4381 tcttgggcaa ggtgttctcc ttaaaggata tggtagcgaa ggccatgact ctggtcactt
     4441 gaactatgct gatattggta agcgtatcgg tggtgtcgaa gacttcaaga ccctaattga
     4501 gaaggctaag aaatatggag ctcatctagg tatccacgtt aacgcttcag aaacttatcc
     4561 tgagtctaaa tacttcaatg aaaaaattct ccgtaagaat ccagatggaa gctatagcta
     4621 tggttggaac tggctagatc aaggtatcaa cattgatgct gcctatgacc tagctcatgg
     4681 tcgtttggca cgttgggaag atttgaagaa aaaacttggt gacggtctcg actttatcta
     4741 tgtggacgtt tggggtaatg gtcaatcagg tgataacggt gcctgggcta cccacgttct
     4801 tgctaaagaa attaacaaac aaggctggcg ctttgcgatc gagtggggcc atggtggtga
     4861 gtacgactct accttccatc actgggcagc tgacttgacc tacggtggct acaccaataa
     4921 aggtatcaac agtgccatca cccgctttat ccgtaaccac caaaaagatg cttgggtagg
     4981 ggactacaga agttatggtg gtgcagccaa ctatccactg ctaggtggct acagcatgaa
     5041 agactttgaa ggctggcaag gaagaagtga ctacaatggc tatgtgacta acctctttgc
     5101 tcatgacgtc atgactaagt acttccaaca cttcactgta agtaaatggg aaaatggtac
     5161 accggtgact atgaccgata acggtagcac ctataaatgg actccagaaa tgcgagtgga
     5221 gttggtagat gctgacaata ataaagtagt tgtaactcgt aagtcaaatg atgtcaatag
     5281 cccacaatat cgcgaacgta cagtaacgct caacggacgt gtcatccaag atggttcagc
     5341 ttacttgact ccttggaact gggatgcaaa tggtaagaaa ctttctactg agaaggaaaa
     5401 gatgtactac ttcaatacgc aggccggtac aacaacttgg acccttccaa gcgattgggc
     5461 aaagagcaag gtttaccttt acaagctaac tgaccaaggt aagacagaag agcaagaact
     5521 aactgtaaaa gatggtaaaa ttaccctaga tcttctagca aatcaaccat acgttctcta
     5581 tcgttcgaaa caaaccaatc ctgaaatgtc atggagtgaa ggcatgcaca tctatgacca
     5641 aggatttaat agcggtacct tgaaacattg gaccatttca ggcgatgctt ctaaggcaga
     5701 aattgtcaag tctcaagggg caaacgatat gcttcgtatt caaggaaaca aagaaaaagt
     5761 tagtctcact cagaaattaa ctggcttgaa accaaatacc aagtatgccg tttatgtcgg
     5821 tgtcgataac cgtagtaatg ccaaggcgat catcactgta aacactggtg aaaaagaagt
     5881 gactacttat accaataagt ctctcgctct caactatgtt aaggcctacg cccacaatac
     5941 acgtcgtgac aatgctacag ttgacgatac aagttacttc caaaacatgt acgccttctt
     6001 tacaactgga tcggacgtct caaatgttac tctgacattg agtcgtgaag ctggtgatga
     6061 agcaacttac tttgatgaaa ttcgtacctt tgaaaacaat tcaagcatgt acggagacaa
     6121 gcatgataca ggtcaaggaa ccttcaagca agactttgaa aatgttgctc agggtatctt
     6181 cccatttgta gtgggtggtg tcgaaggtgt cgaagacaac cgcactcact tgtctgaaaa
     6241 acacgatcca tatacacaac gtggttggaa cggtaagaaa gttgatgatg ttatcgaagg
     6301 aaattggtca ctcaagacaa atggactagt gagccgtcgt aacttggttt accaaactat
     6361 tccgcaaaac ttccgttttg aagcaggtaa gacctaccgt gtaacctttg aatacgaagc
     6421 aggttcagac aatacctatg cttttgtagt cggtaaggga gaattccagt caggtcgtcg
     6481 tggtactcaa gcaagcaact tggaaatgca tgaattgcca aatacttgga cagattctaa
     6541 gaaagccaag aaggcaacct tcctcgtgac aggtgcagaa acaggggata cttgggtagg
     6601 tatctactca actggaaatg caagtaatac tcgtggtgat tctggtggaa atgccaactt
     6661 ccgtggttat aacgacttca tgatggataa tcttcaaatc gaagaaatta ccctaacagg
     6721 taatatgttg acagaaaatg ctctgaagaa ctacttgcca acggttgcca tgactaacta
     6781 caccaaagag tctatggatg ctttgaaaga ggcggtcttt aaccttagtc aggccgatga
     6841 tgatatcagt gtggaagaag cgcgtgcaga gattgccaag attgaaacct tgaagaatgc
     6901 tttggttcag aagaaaacgg ctttggtagc agatgacttt gcaagtctta cagctcctgc
     6961 tcaggctcaa gaaggtcttg caaatgcctt tgatggaaac ttatctagtc tatggcatac
     7021 atcttggaat ggtggagatg taggcaagcc tgcaaccatg gtcttgaaag aaccaactga
     7081 aatcactgga cttcgttatg ttccacgtgg atcaggttca aatggtaact tgcgtgatgt
     7141 gaaacttgtt gtgacagatg agtctggcaa ggagcatacc tttactgcaa ctgattggcc
     7201 agataacaat aagccaaaag acattgattt tggtaagaca attaaggcta agaaaattgt
     7261 ccttacaggt actaagactt acggagatgg tggcgataaa taccaatctg cagcggaact
     7321 catctttact cgtccacagg tagcagaaac acctcttgac ttgtcaggct atgaagcagc
     7381 tttgactaag gctcagaaat taacagacaa agacaatcaa gaggaagtag ctagcgttca
     7441 ggcaagcatg aaatatgcga cggataacca tctcttgacg gaaagaatgg tggaatactt
     7501 tgcagattat ctcaaccaat taaaagattc tgctacgaaa ccagatgctc caactgtaga
     7561 gaaacctgag tttaaactta gctctttagc ttccgagcaa ggtaagacgc cagattataa
     7621 gcaagaaata gctagaccag aaacacctga acaaatcttg ccagcaacag gtgagagtca
     7681 atctgacaca gccctcttcc tagcaggtgt tagcctagcc ctatctgctc tctttgtagt
     7741 aaaaacgaag aaagactagt atttagtaaa acctcttaac aagattacgg aagcagtctc
     7801 tatcttttcc aatgaggttt atagtacaga aaaagcctga gaagatgtct tctcaggctt
     7861 ttgttaagca cataaataca atagtgctat gaaaaaatca cccagaaaaa tctgggtgat
     7921 aaatgttatg gttgtgctga ttgaggattc tgattttgtt gatcaggggt tgtatttgat
     7981 tgttgcgtat tattgttagg attggtagtc gtactattat ttgtgcttgg agtggttgag
     8041 ctagactgtg aagttgaact atctgatgat gagcttgaac tttcagttga tgggggttgt
     8101 tgtggagcag gtgagctcca cgtagaacga gcaccatttt taaatacgaa ttctccattt
     8161 ctgtagagcc cctctggtat attccaatcc tctggattgc ttccttcaga caggtaggtc
     8221 atcatagagc ggtaaacttt ggcagcgacc gtaaggccat tgcctacaag tggtgtcaga
     8281 cggttagaat agcctgtcca tacagccatt gaatatttac gcgtatagcc agcaaatagt
     8341 tcatcaggtg ctacaaattg agaggtcttg atgtggtttt caatttcctc gtctgtatag
     8401 ttagaggttc ctgttttacc agcctgaggg agccaagcaa gataggcatt tcgtccagtt
     8461 ccataactca agactgtttt catcatgtcg gtcatcatat aggctgtcgt ttccttcatg
     8521 gcacgagttc cgacattaga gaactctttt tcactcccat cactaaagac gactttatgg
     8581 atatacattg gtttatagta agttccacca tttgcaaagg cagcgtaagc agcagccatc
     8641 ttttcactac ttgctccata ttttttgtct gattcggttg tgttacttga aatggcattt
     8701 gagtagtgaa tacttgggta gtcgattccg agaccattta ggaaagtctt ggcgcggttg
     8761 agtccgacct tgtttagagt ttccacggct gggacgtttc gcgattgttg cagggcgtat
     8821 tgcaaggtga tgttgccaaa gtagccccta tcccagttat aaacaggagt atttgtccca
     8881 gggtagttat agggctcatc gtgaacgata gtagcagttg aatcgtagac accgtactcc
     8941 aaggcaggag catagtctgt gatcggtttc atagttgatc cccagtcgcg gtttgtttct
     9001 actgcttggt taattccgaa ggaaacatta cttgactgat ggcgtgctcc tagctgggca
     9061 atgactttac cgttagaaac atcaacaatg gtagaagcga cttgcaattc atcgtctgga
     9121 taggcaacgt attcgtctgt attgtaaata tcccacagat gtttttgagc ttcttggtct
     9181 acatttgtgt agacatccat cccagttgtg agcaggttat agcctgtttc ttcttcaact
     9241 tgattgatga cttccttgag gtaattatcc atgtaagcag ggtaattact tgctgatttg
     9301 agactttgta gtccatcagt aattggtgta ttgactgctt tctcatactg ttcagcagag
     9361 atgtagcctt gatttttcat ttcagataag accaagtttc ggcggtcttg ggctgcttct
     9421 ggatgtgaat aggggtcata ttggtttggt gcctgaggca ttccagccag caaggctaac
     9481 tgaggtaaac ttaaattatt gaggtcttta ccatagtagt tttgagctgc tgtctgcatt
     9541 ccatagttcc cattagacat gtagacctta tttatatagt aggtcaagat ttcttgcttg
     9601 gttgcttttt gttctaactg aatcgctaac caagcttcct gagccttacg agaaatagtc
     9661 tggtcggaag tcgaagttga aaagtaagtc aacttaatca actgttgagt gagagttgat
     9721 ccaccttgga gggaattgct ttgcagattg cgcaagaaag ctcccaggat acggatggta
     9781 tcaatccccc tgtggtcgaa gaagcgatgg tcttcgatag aaacgattgc cttaaccaaa
     9841 tctgtgggaa tatcattagc ttgggcattg acgcggcgtt cagaacccaa gtcagcaatg
     9901 agttgatttt tattgtcgta gattttacta gaagttgttg caactagttt actctcggat
     9961 aggctaggag ccttgctaac gtagtagaaa aaaactcctc cgcctaagac aatggctgcg
    10021 ataaccaagc ttaagaagct aatgctcaga tacttgatta ggcgcagaat cgttggtttg
    10081 ttcatcttgt tttaccacct aataaatgtt ctttgataac attgagataa ggaatttgag
    10141 ggaaggcacc agccttgatt tcatatccat attctcgaat atattcaagt ggcattgatt
    10201 tttgtctctt atcttgatga tagaagcgaa tcaaatcgaa tgccggcaat aagtaggttt
    10261 cttgctgaga agaaaagtga agaaggacaa agcagattcc ttgttgggca aggacttgtt
    10321 ccatatgctg aatctgatgt ggatgaaaat ttttcatcgg aatcgcacgt ttttgttttg
    10381 tttccttgac ttcaaagtcg atgtaatatc cattataaac gccagaatag tccgtcgttg
    10441 aagcttgtcg aaaataggct tcaacaatct tggcacgact tcgttgtgga tagtccactt
    10501 gtacgatttg aataggagtt ggtttcttat gtataacagc caagccctga gacaaatagt
    10561 agtcgttggt agcattgatc atcttttcaa aagacattcc tcgatttgcg aaatttttgg
    10621 gttgagaaag agatgtttgt cttttttgtg atgaaacttt atgtggatag ttgaccataa
    10681 ttctccttat tggtacaata acatcacttt attataccat aatttgcaca gaaagggtta
    10741 aaaatggcta cagctttggt tttaggctat tctgcttttg atttgggttt attttctgat
    10801 aaggatcctc gtcttaaatt gattaaaaaa gcgatacgta aagatttaga ggctatggca
    10861 gcagatgggg tgtcttggct tgtgtttaca gggagtttgg gttttgaata ttgggtttta
    10921 gaggttgctc aggagatgaa aaccgaatac ggtttccagt tggccaccat ttttgctttt
    10981 gaaacccatg gggaaaattg gaatgaaggc aatcagatga aactgagtcg ctttaagcag
    11041 gtagactttg tcaaatatgc ttatcctcgc tatgaacaca aggggcagtt aagagattac
    11101 cagcagtttt tgctggaaaa cacgactagt tcctatcttt tttatgatga agaaaatgaa
    11161 acaaaactag cttattttta ccaaaagatg aaaaatcaag aggactattt tataaagaga
    11221 ttaacatttg atgaattaaa tgaacttgct gaaaattttt ccgaaaattg aagctttgac
    11281 cttgattttt gtttgccttt ttttatataa taatactagc aagcgagaat ggagagagac
    11341 atggcaagta ttattttttc agcgaaagat atttttgaac aagagtttgg acgtgaagtc
    11401 cgtggctata ataaagtaga agttgacgag tttttagacg atgtcatcaa ggactatgaa
    11461 acctatgctg ccttggtcaa gtcacttcgt caggaaattg cggatttgaa ggaagaatta
    11521 actcttaaac cgaaaccttc accagttcaa gcagaacccc ttgaagcggc aattacaagt
    11581 tctatgacga attttgatat tttgaaacgc ctgaatagat tggaaaaaga agtttttggt
    11641 aaacaaattt tagataactc agatttttaa gtagttattt gagatgtgca atttttggat
    11701 aatcgcgtga ggagaattgc ttctcatgag gaaagtccat gctagcacag gctgtgatgc
    11761 ctgtagtgtt tgtgctaggc gaaaccataa gcctagggac gagaaatcgt tacggcagtt
    11821 gaaatggcta agtccttgga taggccagag taggcttgaa agtgccacag tgacggagtc
    11881 tttctggaaa cagagagagt ggaacgcggt aaacccctca agctagcaac ccaaattttg
    11941 gtcggggcat ggagtacgcg gaaacgaacg tagtattctg actgctatca gctagagctg
    12001 ttagtggtag acagatgatt atcgaaggaa gtggtcctag tcacttctgg aacaaaacat
    12061 ggcttataga aaattgcata taggttgggg ctgagaaatt ttctcaacct cattttttaa
    12121 agtggacata tagaaaggtc ttgcaagact gtaacatgaa aaaagaattt aatttaattg
    12181 caactgtggc agcagggctt gaggctgtcg ttggtcgtga agtgcgagag ttgggctacg
    12241 attgtcaggt tgaaaatgga cgtgttcgtt ttcaaggaga cgtgagagct attatcgaaa
    12301 ccaacctttg gcttcgggca gcagatcgta tcaaaattat cgtaggaacg ttcccagcta
    12361 agacttttga agagctattt cagggagttt tcgctttaga ttgggaaaat tatttaccac
    12421 ttggagctcg gttcccgatt tcaaaagcta aatgtgttaa gtccaaactt cacaatgagc
    12481 ccagtgttca ggctatttct aagaaagctg ttgtcaagaa attgcagaaa cactatgctc
    12541 gcccagaagg ggttcctctg atggagaatg gcccagagtt taagattgag gtctctattc
    12601 tcaaagatgt ggcaactgtc atgattgata cgaccgggtc tagcctcttt aaacgtggtt
    12661 atcgtaccga aaaaggtggc gctcctatca aggaaaatat ggcagcagcc attttacaac
    12721 tttctaactg gtatccagac aagcctttga ttgatccgac ctgtggttcg gggactttct
    12781 gtattgaggc agttatgatt gctagaaaga tggcgccagg tcttcgtcgc tcttttgcat
    12841 ttgaggaatg gaactggatc agcgatcgct tgattcaaga agtgcgcaca gaagcggcta
    12901 aaaaagtaga acgtgagctt gagttggata tcatgggctg tgatattgat gctcgcatgg
    12961 tggaaattgc taaggccaat gctcaggcag ctggtgttgc aggagacatt acttttaagc
    13021 agatgcgcgt gcaggattta cgttccgata aaatcaatgg agtaatcatt tccaatccgc
    13081 cttatggtga acgtttgtca gatgatgcag gggtgaccaa gctctatgct gagatggggc
    13141 aagtatttgc accgctgaaa acttggagca aatttatcct gactagtgat gaagcttttg
    13201 aaagcaagta tggtagccaa gcagataaga agcgtaagtt atacaacgga accttgaaag
    13261 tggatctata tcaatatttt ggtcagcgtg tcaaacggca agaggtaaaa tagaaaggga
    13321 tactcatgag taaaaaaaga cgaaatcgtc ataaaaaaga aggtcaagaa ccgcaatttg
    13381 attttgatga agcaaaagag ctaacagttg gtcaagctat tcgtaaaaat gaagaagtgg
    13441 aagcaggagt cttgcctgag gattccattt tggacaagta tgttaagcaa cacagagatg
    13501 aaattgaggc ggataagttt gcgactcgtc aatacaaaaa agaggagttc gttgaaactc
    13561 agagtctgga tgatttaatt caagagatgc gtgaggctgt agagaagtca gaagcttctt
    13621 cggaggaagt tccatcttct gaagacatct tactaccctt gcctctggac gatgaggagc
    13681 aaggcttgga tcctctattg ctagatgatg aaaatccaac agaaatgact gaagaagtgg
    13741 aagaggagca aaacctttct cgtctggatc aagaggactc agaaaagaaa agtaaaaaag
    13801 gctttatttt gaccgttttg gcgcttgtat cagtaattat ttgtgtcagt gcttattatg
    13861 tctaccgtca agtggctcgt tcgaccaagg aaattgaaac ttctcaatca actacagcca
    13921 atcaatcaga tgtggatgat tttaatacac tttatgacgc cttttacaca gatagcaata
    13981 aaacggcttt gaaaaatagc cagtttgata aactgagtca actcaaaacc ttgcttgata
    14041 aactggaagg tagtcgtgaa catacgcttg ccaaatctaa atatgatagt ctagcaacgc
    14101 aaatcaaggc tattcaagat gtcaatgcac aatttgaaaa accagctatt gtggatggtg
    14161 tgttggatac caatgccaaa gccaaatcgg atgctaaatt tacggatatt aaaactggaa
    14221 atacggagct tgataaagtg ctagataagg ctatcagtct tggtaagagc cagcaaacaa
    14281 gtacttctag ctcaagttca agtcaaacta gcagctcaag ctctagtcaa gcaagttcaa
    14341 atacgactag tgagccaaaa ccaagtagtt caaatgagac tagaagtagt cgcagtgaag
    14401 tcaatatggg tctctcgagt gcaggggttg ctgttcaaag aagtgccagt cgtgttgcct
    14461 ataatcagtc tgctattgat gatagtaata actctgcctg ggattttgcg gatggtgtct
    14521 tggaacaaat tctagcgact tcacgttcac gtggctatat cactggagac caatatatcc
    14581 ttgaacgtgt caatatcgtt aacggcaatg gttattacaa cctctataag ccagatggaa
    14641 cctatctctt tacccttaac tgtaagacag gctactttgt cggaaatggc gctggtcatg
    14701 cggatgactt ggactactaa gcagtcgtta caaaattctt tcttttcaaa agtaaaaatg
    14761 ataaaataaa acaaatgaaa caagaggagt gtcaaatgac aaaagctaac tttggtgtcg
    14821 taggtatggc cgtaatgggt cgtaaccttg cccttaatat tgaatcacgt ggttacacag
    14881 ttgctatcta caaccgtagt aaagaaaaaa cggaagatgt gattgcttgc catcctgaaa
    14941 agaactttgt accaagctat gacgttgaaa gttttgtaaa ctcaatcgaa aaacctcgtc
    15001 gtatcatgct gatggttcaa gctggacctg gtacagatgc tactatccaa gcccttcttc
    15061 cacaccttga caagggtgat atcttgattg acggtggaaa tactttctac aaagatacca
    15121 tccgtcgtaa tgaagaattg gcaaactcag gtatcaactt tatcggtact ggagtttctg
    15181 gtggtgaaaa aggtgccctt gaaggtcctt ctatcatgcc tggtggacaa aaagaggcct
    15241 acgaattggt tgcggatgtt cttgaagaaa tctcagctaa agcaccagaa gatggcaagc
    15301 catgtgtgac ttacatcggt cctgatggag ctggtcacta tgtgaaaatg gttcacaatg
    15361 gtattgagta cggtgatatg caattgatcg cagaaagcta tgacttgatg caacacttgc
    15421 taggcctttc tgcagaggat atggctgaaa tctttactga gtggaacaag ggtgaattag
    15481 acagctactt gatcgaaatc acagctgata tcttgagccg taaagacgat gaaggccaag
    15541 atggaccaat cgtagactac atccttgatg ctgcaggtaa caagggaact ggtaaatgga
    15601 cgagccaatc atctcttgac cttggtgtac cattgtcact gattactgag tcagtgtttg
    15661 cacgctacat ttcaacttac aaggaagaac gtgtacatgc tagcaaggtg cttccaaaac
    15721 cagctgcctt caactttgaa ggagacaagg ctgaattgat tgaaaaaatc cgtcaagccc
    15781 tttacttctc aaaaatcatt tcatacgcac aaggatttgc tcaattgcgt gtagcctcta
    15841 aagaaaacaa ctggaacttg ccatttgcag atatcgcatc tatctggcgt gatggctgta
    15901 tcatccgttc tcgtttcttg caaaagatta cagatgctta caaccgcgat gcagatcttg
    15961 ccaaccttct tttggacgag tacttcttgg atgttactgc taagtatcaa caagcagtgc
    16021 gtgatatcgt agctcttgcg gttcaagctg gtgtgccagt gccaactttc tcagcagcta
    16081 ttacttactt tgatagctac cgttcagctg accttccagc taacttgatc caagcacaac
    16141 gtgactactt tggtgctcac acttaccaac gtaaagacaa agaaggaacc ttccactact
    16201 cttggtatga cgaaaaataa gtaggtcagc catggggaaa cggattttat tacttgagaa
    16261 agaacgaaat ctagctcatt ttttaagttt ggaactccag aaagagcagt atcgggttga
    16321 tctggtagag gaggggcaaa aagccctctc catggctctt cagacagact atgatttgat
    16381 gttattgaac gttaatctgg gagatatgat ggctcaggat tttgcagaaa aattgagtcg
    16441 aactaaacct gcctcagtca tcatgatttt agatcattgg gaagacttgc aagaagagct
    16501 ggaagttgtt cagcgttttg cagtttcata catttataag ccagtcctta tcgaaaatct
    16561 ggtagcgcgt atttcggcga tcttccgagg tcgggacttc attgatcaac actgcagtct
    16621 gatgaaagtt ccaaggacct accgcaatct taggatagat gttgaacatc acacggttta
    16681 tcgtggtgaa gagatgattg ctctgacccg ccgtgagtat gaccttttgg cgacacttat
    16741 gggaagcaag aaagtattga ctcgtgagca attgttggaa agtgtttgga agtatgaaag
    16801 tgcgaccgag acaaatatcg tagatgtcta tatccgctat ctacggagca agcttgatgt
    16861 taaaggccaa aaaagctaca ttaaaaccgt gcgtggtgtt ggatatacca tgcaagaata
    16921 gataagcagt tgcagttgtg taactgcttt tttgaggagt ttttatatat tgacatgcag
    16981 tcgggtcttt gctacaatcg ttttaggagg atatatagat gaaacttttg aaaaaaatga
    17041 tgcaagttct actagcagtc tttttctttg gtttgctagc tacaaatacg gtatttgcga
    17101 ataccacagg tggccgattt gttgataagg ataatagaaa atattatgta aaagatgatc
    17161 ataaagcaat ctattggcat aaaatagacg gtaaaactta ctattttggt gatattggag
    17221 agatggttgt cggttggcaa tacttagaaa ttcctggaac aggttatcgt gataatttat
    17281 tcgataacca accagttaat gaaattggcc ttcaggagaa gtggtactat tttggacaag
    17341 atggtgcttt gctagaacaa acagataaac aagtactaga ggcaaaaacg tctgaaaata
    17401 caggaaaagt atacggtgaa caatatcctc tatctgctga aaagagaact tattattttg
    17461 ataataatta tgctgtaaag acaggctgga tttatgaaga cggcaattgg tattatttaa
    17521 ataagctagg aaattttggc gatgattctt acaatccact accaattagt gaagttgcta
    17581 agggttggac tcaagatttt catgttacta ttgacattga tagaagcaaa cctgctccat
    17641 ggtactacct agacccagaa actggcatta tgcgaacagg atggcaatat ctaggtaata
    17701 actggtacta cctccgttca tcaggagcaa tggccactgg ctggtatcag gaaggtacca
    17761 cttggtatta tttagaccag ccaaatggcg atatgaaaac aggttggcaa aaccttggga
    17821 acaaatggta ctatctccgt tcatcaggag ctatggcaac tggttggtat caagatggtt
    17881 caacttggta ctacctaaat gcaggtaatg gagacatgaa gacaggttgg ttccaggtca
    17941 atggcaactg gtactatgct tatagctcag gtgctttggc agtgaatacg accgtagatg
    18001 gctattctgt caactataat ggcgaatggg ttcggtaatg acagggcgct tataattata
    18061 ttagaacact cgcttaatca aagaagtgac tttgttgtac ttgacctgac gattggggag
    18121 attaaaagca tgtgaaatct acacatgctt tttcgttagt tatgagtgtt gaacttgact
    18181 aaccattgac aaaagataag agcaattaaa ataagataca aaaatatcaa tgctaactgc
    18241 accgaaacgc ccgatgctat ggatagggct aatagggaga gcagggacgg ggcgagaatg
    18301 tccactgtgc tcagagcaga gcccaccgtc cccatcttgt cactggggat ataggcaaag
    18361 acagctgctt gtaggcgagg gctgagaatg ccgataatcg tagaactgat gaaactggtc
    18421 atgaaaatta cgatataggc ttgacaaagg atactagtta ttagagccaa tagggaaatc
    18481 tcacagaaaa ccaagaggtg cgtgaaacgg atatttttaa atagattact gctggtcata
    18541 ttgccaagga tagctccaca agacatgatg atggagagca gggcgaggag ttgcccaatg
    18601 ctcagttgtg ctagtgtctg ttggatgaag cggagggcaa tcagccgagg ggacacatcc
    18661 aagatggcaa tcatactggt cgtcagaaac agtagtatga cggtatcttt taacttcagt
    18721 agcacagcca gcgactgttt aagatgttga aaatatttct taaaactcag tgctgtatgt
    18781 gacatttcaa tccttttttc aacctcatac aaggtatgtc gaataacata caggcccaaa
    18841 aaggcaatga caaaagtcag agtgttgata agggaaatag tttgaatact tataacattg
    18901 ataaggaatg cgccagccag attggcgaca atgcggacaa ccctcatcag agactgcctg
    18961 aaccccatgg catcatgcag gtcgtcctta attacactga tgtagagggc gttcatcatg
    19021 taggcagaca ggtagctcaa ggtgtcagag atgaggttga tgatgacaat cataatgact
    19081 gaaactaatg aaaagggcga caagacgaga aatactgtca aaatagcgta gagcaggatt
    19141 ttgattttgg caatacagag tgcgtgtttg actctatttt cttgaaaatc tcctagaatc
    19201 ccgagaaaga gttgcgatag taggggaacc atctctgaaa tggaaatcag taaaatcgct
    19261 agcggagcga aattgtactg agccacataa ttgataatgg cgaggtagaa aatactgtcg
    19321 ccgaatgatg aaaaacagct gtttagcagc aactgtctat atatgttgtt tgtccaaaat
    19381 aatttcatac atttctcctt atgtctgcac atcgaatggg aatttattat ttaatagaca
    19441 ccaatatacc cccatgcttc ctattccgaa gtcaaacaaa tctgctttac cactatctcc
    19501 ttgaaacatc agtaaaccgt gatcatctcg ttcagaacat gctaaaatta cctgttggat
    19561 tttttcatca gtaatttgtt ttgattgtag acagtggttt gtagtaagct agttattccg
    19621 tggcaatatc ctgtcatcat ttttagatga tggttaaaaa caaattcttg atatttacta
    19681 ataatatctt tgtttccgtc acaatcgtac atacaaagat ataagattat tccggaaatt
    19741 cctttgcacc aagaaagttg taaatttcct aaattttcag tattagaagt aactttttct
    19801 aataattttt ttaattcagt atggaatgta tggagatcat tatagaacat agaaggttct
    19861 aagactttag aataggcaaa taaagcatat gcaattccac aatatccatg agcaaagcta
    19921 tagtctaaaa tgctttcttt ggctgtatct ctttgtagga aataatgata aatttcccca
    19981 tatactattg tggatgaaag ttttaagagt attgtcattg gtaacttgat agtattttat
    20041 taatgataat aggacaccag attttcccaa tgcaaagtct atttcctcta gagtatcata
    20101 attctctatt aatttcttag cggtgacgtt tgctaattgt agatagtatt gatttttact
    20161 gatagaaaat aaatgtagga gtaactatag atagcctgca ccaccaaata gcagtgagta
    20221 ttgatattca tatgtgtgtg acgttctaat tgtcactgcc ttcttgatga tagagagtat
    20281 tttagaatcc agttctgggt ggtacaattt atttagagga aacagtagtc cagctattcc
    20341 gtgttggaat gataaattac ttacgaaatt tccaaattct gttgaagaag tgatccttcc
    20401 ttcagaattt acagttttat ctagtaaaaa tcgtagaaca ctattacatt ctgttttgta
    20461 atcatattta tgttcctcta tttttttaat tttgactaaa ttatttgttt gacttaaatt
    20521 tagtagacat tgtaaccaaa atagttgctc atctgtgagc tgaccttgag tatgtgatag
    20581 ttctagtaat tgaataggat cctttagtta gattcaatca atctataaca caacaacata
    20641 ataatacttt taggataact tgtcaaata
//
LOCUS       DAVBNZ010000038        20133 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000038 DAVBNZ010000000
VERSION     DAVBNZ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20133
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.038"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            638..952
                     /locus_tag="VQ860_001431"
     CDS             638..952
                     /locus_tag="VQ860_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3119847.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            968..1354
                     /locus_tag="VQ860_001432"
     CDS             968..1354
                     /locus_tag="VQ860_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3119848.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1383..2768
                     /locus_tag="VQ860_001433"
     CDS             1383..2768
                     /locus_tag="VQ860_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3119849.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESDLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2771..2923
                     /locus_tag="VQ860_001434"
     CDS             2771..2923
                     /locus_tag="VQ860_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3119850.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2946..4151
                     /locus_tag="VQ860_001435"
     CDS             2946..4151
                     /locus_tag="VQ860_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HET3119851.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            4194..4415
                     /locus_tag="VQ860_001436"
     CDS             4194..4415
                     /locus_tag="VQ860_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119852.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            4532..5029
                     /locus_tag="VQ860_001437"
     CDS             4532..5029
                     /locus_tag="VQ860_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HET3119853.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            5004..5510
                     /locus_tag="VQ860_001438"
     CDS             5004..5510
                     /locus_tag="VQ860_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3119854.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAEKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            5494..7941
                     /locus_tag="VQ860_001439"
     CDS             5494..7941
                     /locus_tag="VQ860_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3119855.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            7944..10121
                     /locus_tag="VQ860_001440"
     CDS             7944..10121
                     /locus_tag="VQ860_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3119856.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            10118..11119
                     /locus_tag="VQ860_001441"
     CDS             10118..11119
                     /locus_tag="VQ860_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3119857.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            11116..12051
                     /locus_tag="VQ860_001442"
     CDS             11116..12051
                     /locus_tag="VQ860_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3119858.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            12296..12412
                     /locus_tag="VQ860_001443"
     CDS             12296..12412
                     /locus_tag="VQ860_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3119859.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            12428..14347
                     /gene="tet(M)"
                     /locus_tag="VQ860_001444"
     CDS             12428..14347
                     /gene="tet(M)"
                     /locus_tag="VQ860_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3119860.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            14466..14633
                     /locus_tag="VQ860_001445"
     CDS             14466..14633
                     /locus_tag="VQ860_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3119861.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(14693..15046)
                     /locus_tag="VQ860_001446"
     CDS             complement(14693..15046)
                     /locus_tag="VQ860_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3119862.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            15551..15973
                     /locus_tag="VQ860_001447"
     CDS             15551..15973
                     /locus_tag="VQ860_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3119863.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            15970..16200
                     /locus_tag="VQ860_001448"
     CDS             15970..16200
                     /locus_tag="VQ860_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3119864.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            16661..16864
                     /locus_tag="VQ860_001449"
     CDS             16661..16864
                     /locus_tag="VQ860_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3119865.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            16946..18163
                     /locus_tag="VQ860_001450"
     CDS             16946..18163
                     /locus_tag="VQ860_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3119866.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(18325..18927)
                     /locus_tag="VQ860_001451"
     CDS             complement(18325..18927)
                     /locus_tag="VQ860_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3119867.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQIIYGASLIS
                     FLWMYGQRKQVAKVNMETRIKWIGIGFVSLLIISLYFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLFNKNKV"
     gene            complement(18930..19163)
                     /locus_tag="VQ860_001452"
     CDS             complement(18930..19163)
                     /locus_tag="VQ860_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3119868.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            complement(19176..19556)
                     /locus_tag="VQ860_001453"
     CDS             complement(19176..19556)
                     /locus_tag="VQ860_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119869.1"
                     /translation="MIDLYLSKNNHRNQLLLEFFQNYGIEVSCHSISEMTRDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(19549..19998)
                     /locus_tag="VQ860_001454"
     CDS             complement(19549..19998)
                     /locus_tag="VQ860_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119870.1"
                     /translation="MKALNKESILYCDELETELHDAEMMQLDEQIFLMPNYPCEFEVT
                     FLDYYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFIDDNHNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKSINFSNLLDSLIVSEYQMEPNLWEVSHD"
     gene            complement(19982..>20133)
                     /locus_tag="VQ860_001455"
     CDS             complement(19982..>20133)
                     /locus_tag="VQ860_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET3119871.1"
                     /translation="FPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEK
                     DESAK"
BASE COUNT         6594 a         3646 c         4068 g         5825 t
ORIGIN      
        1 agtctggtaa cgataaactc cgtgtctgtt agaaaattct cacacacgtc ttgtgccagt
       61 tgcccttcac agggaaatac tctcagtccc tacttacaca ggcacgctaa tcaagacgga
      121 gtggattcaa ttttcaaaga acaggtagct ttattataga gaagagtagt tgaaattttt
      181 atcacatttt ttatttttct gtagagctaa attcatacta aacaaagatt ttgaaataaa
      241 agactaacat tgttacataa cgttagcatt tcatttccct aaaataagct aattttgtct
      301 aaaaaatagc ataaaaatct agttatccgc ataaaaactg gacttatcac actttatcaa
      361 ggtcaaaacc actcaattta ctactaattt actacttatg aatgagcttt gatacgacga
      421 tttatccttg aaaagtgaag atataaagat acttccaata aaatttgaat atttaatagg
      481 tagacacttc aaaaaatgag gtgtctattt ttttacccga ttttgaaagg aagtgaactt
      541 atgaaaacaa aaaatcaaga atcaaaaggt cgttccccac tctttaagac catcaaacat
      601 tcattcagcc aataaaaaag aaaggatagg taaaaatatg gaacttaaat ttgtgattcc
      661 caacatggaa aaaacattcg gcaatttaga atttgctggc gaggataaag tcgttcagcg
      721 aagaatcaac ggacggctaa ctgtcttatc aagaagctat aatctctatt ctgatgttca
      781 aagagcagat gatattgtgg tggtgcttcc tgctgaagct ggcgaaaaac atttcggctt
      841 tgaggaacgt gtgaagttag tcaatccacg tattaccgca gagggctaca aaatcggcac
      901 tcgtggtttt acaaattacc ttttacatgc tgacgacatg ataaaagaat aaagaaagag
      961 aggaaaaatg atgagattag caaatggcat tgtattagat aaagacacga cttttggaga
     1021 attgaaattc tctgctctac gtcgtgaagt gagaatccaa aatgaagacg ggtcggtttc
     1081 agatgaaatc aaggaacgta cctatgactt aaaatccaaa ggacaaggac gcatgattca
     1141 agtaagtatt cctgccagcg tgcctttgaa agagtttgat tataacgcac gggtggaact
     1201 tatcaatccc attgcggaca ccgttgctac tgccacctat caaggagcag atgttgactg
     1261 gtatatcaag gcagacgata ttgtgctgac aaaggattct agttcattca aagctcaacc
     1321 acaagcaaag aaagaaccga cacaagacaa atagtcgcta ggtagaaagg agactttttc
     1381 gcatgaaaca gcgtggtaaa aggattcgcc catctggtaa agatttagtc tttcatttta
     1441 cgatagcgtc actcctgcct gttttcctgc tggttgtcgg actgtttcat gtgaagacaa
     1501 tccagcagat caactggcag gattttaacc tatcacaagc agataagatt gacattccct
     1561 atttaattat cagtttcagt gtcgcaattc ttatctgctt gctggtagcg tttgtattca
     1621 aacgggttcg ctatgatacg gttaaacaac tttaccaccg tcaaaaactg gcaaagatga
     1681 tacttgaaaa caagtggtat gaatctgaac aggtcaaaac agagggtttc tttaaagata
     1741 gtgctggtcg tacaaaggaa aagataacct acttccctaa aatgtattat cgacttaaaa
     1801 atggcttgat acagatacgg gtggaaatca cgctgggaaa atatcaagac caactcttac
     1861 acttggaaaa gaaattagag agtgacttgt actgtgagct gacggataaa gagttaaagg
     1921 attcctatgt ggaatatact ttgctctatg acaccatagc cagtcgtatt tctattgatg
     1981 aagtagaagc taaagatggt aaacttcgct taatgaaaaa cgtatggtgg gaatatgata
     2041 agctccctca tatgttgatt gctggtggta caggtggcgg taaaacttac tttatactga
     2101 cactgattga agccttgctt catacagatt caaaactgta tattcttgac ccgaaaaatg
     2161 ctgaccttgc ggacttaggt tctgtgatgg caaatgtcta ctatagaaaa gaagacttgc
     2221 tttcttgcat tgaaacattc tatgaagaaa tgatgaaacg tagtgaggaa atgaagcaga
     2281 tgaagaacta taagactggc aaaaattatg cttacttagg tctcccggca cacttcttaa
     2341 tctttgatga atacgtcgct ttcatggaaa tgctgggaac aaaagaaaac accgcagtta
     2401 tgaataagct gaaacagatt gtcatgttag gtcgtcaagc tggcttcttt ctaatactgg
     2461 cttgtcaacg tccagacgca aaatatttag gcgacggaat ccgtgatcag tttaatttca
     2521 gagtggcttt aggtcgtatg tctgaaatgg gctatggcat gatgtttggc agtgacgtac
     2581 aaaaggattt cttcttaaag cgaatcaaag gtcgtggcta tgttgatgta ggaacaagtg
     2641 tcatatcaga gttttatact ccccttgtac caaaaggata tgatttcttg gaggaaatta
     2701 aaaagttatc caacagcaga cagtccacgc aggcgacgtg cgaagcggaa gtcgcaggtg
     2761 tggactgatc ttgctggctg gtgtggcaat agccacgcca gcacttaacc ccccgtatct
     2821 aacagggggg tacaaatcga caggaaacag tcaaaaaaac attagaaaat cctttggtta
     2881 caagggattt acaaaatttc agcgtatgtc aaatgggctt taaaagttga catacgcctt
     2941 tttgattgga gggattttta ctgaatgaac aaacttggtt acagcattta aaagaaaaac
     3001 gcttggctta tggactatct caaaaccgtt tagctgttgc gactggtatt acaaggcagt
     3061 atctaagcga tattgaaaca ggaaaagtca agccatcaga ggatttacag cagtcccttt
     3121 gggaagctct ggaacgcttc aatcccgacg ctccccttga aatgctgttt gattatgtaa
     3181 ggattcgctt tccgacaaca gacgtacagc aggtggtcga aaacatctta caactgaaac
     3241 tgtcctattt tcttcatgag gactatggtt tctattctta ttcagagcat tatgctttag
     3301 gcgacatatt cgtcctttgc tcccatgaac tggacaaagg agttctggtg gaattgaaag
     3361 gtcgtgggtg cagacaattt gaaagctatc ttctggcaca acaaagaagc tggtatgagt
     3421 tctttatgga cgttttggtg gctggcggtg tgatgaaacg ccttgacctt gccattaacg
     3481 ataagacagg gattttgaat atccctgtac tcactgaaaa gtgccaacag gaagaatgta
     3541 tctccgtctt ccgcagtttt aaaagctatc gcagtggcga actggtacgc aaagaggaaa
     3601 aggaatgtat gggaaacacc ctctatatcg gttcattaca aagtgaagtt tatttctgta
     3661 tctatgaaaa ggactacgag cagtacaaga aaaatgatat tcccattgaa gacgcagaag
     3721 taaaaaaccg ttttgagatt cgattgaaaa atgagcgtgc ctattatgca gtccgtgatt
     3781 tactcgtcta tgacaatcca gagcataccg cctttaaaat tatcaatcgg tatatccgtt
     3841 ttgtagataa agacgattcc aaacctcgtt ctgattggaa actgaatgaa gaatgggctt
     3901 ggtttattgg gaacaatcgt gaacgattaa aactaaccac aaaaccagag ccttactcct
     3961 tccaaaggac gctgaactgg ctatctcatc aagttgcccc gaccttaaag gttgcgatta
     4021 aacttgatga aatcaaccag acgcaggttg taaaagacat tctcgaccat gcgaaactga
     4081 cagaccgaca caagcagatt ttgaagcaac agtcagtaaa agaacaggac gtgataacaa
     4141 caaaaaaata actcaaatac aaattcattg aatatagaga ggagaacatt tttatgaatt
     4201 ttggacaaaa cctttataac tggtttctat caaacgctca atcactggtg cttttagcaa
     4261 tcgttgtgat tggcttgtat cttggcttca agcgtgagtt tagcaaactg attggctttt
     4321 taattattgc gattattgcg gttggcttag tcttcaacgc tgctggagta aaagacattt
     4381 tactagagct attcaatcgc attattggtg cttaaataaa accgttcttt tgtggaatat
     4441 aagtggtttt cttatgttcc gcaaaggaat ggtacaccaa acgaagtgcg gtagggattt
     4501 ttgaatctct acaaagaaag gacgtgaata tatggacgat atgcaagtct atattgcgaa
     4561 tttaggcaaa tacaatgagg gcgaattggt cggtgcgtgg tttacctttc ccattgactt
     4621 tgaggaagtc aaagagaaaa tcggcttgaa tgatgaatat gaggaatacg ccattcatga
     4681 ctacgagtta ccctttacgg ttgacgaata cacttccatt ggcgaactca atcgactatg
     4741 ggaaatggta tcggaattac ccgaagaatt acaatcggag ctatctgctc tgctcactca
     4801 tttttcaagc attgaagaac taagcgaaca tcaagaggat attatcattc attccgattg
     4861 tgatgatatg tatgacgtgg cacgctacta cattgaagaa acgggtgctt taggcgaagt
     4921 accagctagt cttcaaaact atattgatta tcaagcctat ggtcgggatt tagacctttc
     4981 aggaacgttt atctcaacca atcatgggat ttttgaaatc gtctattaaa tctgtcggta
     5041 cattactact ggcagatttt ctattttacg gggtggctca atcagctacc cctatttttt
     5101 atgaaaggat tgattacatg aagaaaatac gaagctatac cagtatctgg tctgtggaaa
     5161 aggtactgta ttctatcaat gattttagac ttccgtttcc cataaccttt acgcaaatga
     5221 catggtttgt cgtgtcactc tttgcagtga tgatacttgg caacttgccc cctctttcca
     5281 tgatagaggg agcatttctc aaatactttg ggattcctgt ggctttcaca tggtttatgt
     5341 ctacaaaaac ttttgatggt aaaaagcctt atggattttt gaagtctgtc attgcttatg
     5401 cactgcgacc aaagctgacc tatgcagaaa aaaaagtaac gcttggcaga aaccagccac
     5461 aagaagccat tacagcagtt aggagtgaat tttatggcat atccaattaa atacattgaa
     5521 aacaatctcg tctggaataa agacggggaa tgttatgctt actatgagct tgttccttac
     5581 aattactcat ttctaagtcc agaacagaaa atacaagtgc atgattcttt cagacagctt
     5641 atcgcacaaa atcgtgatgg caaaattcat gctttacaaa tcagtacaga atccagcata
     5701 cgttctgcac aagagcgttc caaaaatgaa gtcactggca agctcaaagc ggttgcctat
     5761 gacaaaatcg accaacagac agacgcttta atatccatga ttggcgaaaa tcaagtgaac
     5821 taccgtttct ttatcggctt taagttgctt ctcaacgatc aggagttttc tatgaaaagt
     5881 cttaccgttg aagcaaaaaa tgctttgtct gattttgtct atgatgtgaa ccataagctg
     5941 atgggcgatt ttgttagtat gagtaatgat gaaatcctgc gttttcagaa gatggaaaag
     6001 ctcttagaaa ataaaatctc tcgtcgtttc aaaatccgca ggttagataa ggacgacttc
     6061 ggctatctga ttgaacacct ttacggacag acaggcactg cctatgaaga gtatgagtac
     6121 catctatcaa agaaaaagct ggataatgaa acgctgatta aatactatga cttgattaag
     6181 cctactcgct gtttggtgga agaaaaacag cgatatttga aaatccagca ggaagatgaa
     6241 accgtctatg tagcttactt taccattaac agcattgtcg gagaactgga cttcccgtcc
     6301 tctgaaatct tctactacca gcaacagcaa tttacattcc cgattgatac gtcaatgaat
     6361 gtggaaattg tagcgaatcg taaagcccta tctactgtcc gcaataaaaa gaaagaactg
     6421 aaagacttgg ataaccacgc ttggcaaagt gataatgaaa ccagctccaa tgtggcggaa
     6481 gctctggaaa gtgtgaatga gctggaaacc aatttagacc aaagcaagga atctatgtac
     6541 aagctgtctt atgtggtaag ggtatcagca aatgatcttg acgaactcaa acgtcgttgt
     6601 aatgaagtga aagattttta tgacgattta agcgtaaaac tggtacgacc atttggggat
     6661 atgctcggct tacatgaaga atttttacct gccagcaagc gttatatgaa tgattatatt
     6721 caatacgtga cctctgattt cctcgctggt ttaggttttg gtgctactca aatgctgggg
     6781 gaaaatgagg ggatttatgt tggctacagc ttagatactg gacgcaatgt ctatctgaaa
     6841 cctgctcttg ccagtcaagg ggttaagggt tcagtaacca atgcgttagc gtcggctttt
     6901 gttggttcgc tgggtggtgg taaatccttt gcgaataacc ttatcgtcta ttatgcggtg
     6961 ctttatgggg cacaagcagt gattgtagac ccaaaagcag aacgtggcag atggaaagaa
     7021 accttgccag agatttccca tgaaatcaat atcgtcactc tgacttctga tgagaaaaac
     7081 aaaggcttac ttgaccctta tgtgattatg aaaaatccca aagattctga atcactggct
     7141 attgatattc tgacattcct tacggggatt tcctctcgtg atggggaacg cttcccaatc
     7201 cttagaaaag ccattcgtgc agtaaccaat agtgaagtac gagggttgat gaaagtgatt
     7261 gaggaattac gggttgagaa tacgccacta agtaccagta tagccgacca tatcgaaagt
     7321 tttacagact atgactttgc acatttatta ttcagtaatg gttatgtgga gcagtctatc
     7381 agcttagaaa aacaactgaa cattatacag gttgcggact tggtacttcc cgacaaggaa
     7441 acttcctttg aggaatatac cactatggag cttttatccg ttgctatgct gattgtcatt
     7501 agtacctttg ctttagactt tatccataca gaccgaagca ttttcaagat tgtagattta
     7561 gacgaagcat ggagcttttt acaggtagca caaggaaaaa cactatctat gaagctggtt
     7621 cgggctggtc gtgctatgaa cgctggggta tatttcgtga cccaaaatac agacgacctc
     7681 ttagatgaaa aactgaaaaa taacctcggc ttaaaatttg catttcgttc cactgacctt
     7741 aacgagatta aaaagacctt agcctttttt ggtgtagacc cagaggacga aaacaatcag
     7801 aagcgattgc gtgatttgga aaacgggcaa tgccttatca gtgatttata tggtcgtgtc
     7861 ggtgtgatac agttccaccc tgtatttgaa gaactgctcc atgcctttga taccagacca
     7921 cctgtgcgaa aagaggtgta aatgtgaaac catcaatagt aaacagaata aaatcaaact
     7981 ggacgctgaa acgtctaggt aaagtggcaa tgacagtggc tttcacactt gtgattgcca
     8041 tttttctttt agccatgctg ggaacggtgg ttcaagctgc gggcttggta gatgatacgg
     8101 tcaatgtggc aaatgaatac agccgatacc cacttgaaaa ctatcaactg gatttttatg
     8161 tggataatag ctggggctgg cttccgtgga actggtcgga cgggattgga aaacaggtca
     8221 tgtatggact atatgccatt accaatttta tttggacaat cagtttgtat gtttccaatg
     8281 cgacaggtta cttagtacag gaagcctatt ccttagactt catttccgct acagcagatt
     8341 ccattggtaa gaatatgcag accttagctg gtgtgagtgc aaacggattt tcaacagagg
     8401 gtttctatgt tggattcctc ttactcttga ttttggttct tggggtttat gttgcctata
     8461 cgggactgat aaagagagaa accacaaagg caattcatgc cattatgaat tttgtgctgg
     8521 tgtttatcct atcggcttcc tttattgcct acgctcccga ctacattaaa aaaatcaatg
     8581 acttttcatc agacatcagt aatgccagtt tatcacttgg cacgaagatt gtcatgcccc
     8641 attccgatag tcaaggcaag gacagcgtgg acttaatcag agatagcctg ttttccatac
     8701 aggttcagca accgtggcta ctgcttcaat acaacagttc agacattgaa agtatcggta
     8761 ttgaccgtgt ggaaagcctg ctctccacca gcccagattc caacaatggc gaagacagag
     8821 aaaaaattgt tgcggaagaa attgaagaca gaagcaatac caatctaacc attacaaaga
     8881 ccattaaccg tttaggtaca gtcttcttcc tatttgtctt caatattggg atttccatat
     8941 ttgtattcct attaacagga atcatgattt tctcgcaggt actttttatc atctatgcta
     9001 tgtttctgcc tgtgagcttt attttaagca tgattccatc atttgatggt atgtcaaaac
     9061 gagccataac aaagctcttt aataccattt tgacacgagc tggaatcaca ttgattatta
     9121 cgacagcatt tagtatttca accatgctct ataccttatc ggctggttat ccgttctttt
     9181 tgattgcttt tctacagatt gtgacctttg caggaatcta cttcaagctg ggcgatttaa
     9241 tgagtatgtt ttctctacag agtaacgatt ctcaaagtgt gggaagtcgt gtgatgagaa
     9301 aacctcgtat gcttatgcac gctcacatgc accgtctaca gcggaaactt ggacgttcca
     9361 tgactactct aggggctggg tctgccattg ttacaggtaa aaaaggacag tcgggttcgg
     9421 ggagttctgc aaggacacaa gcagatcact cccgaccaga cggaaaggaa aaatcaacac
     9481 ttggaaaacg tatcggtcaa accatcggta cagtagctga taccaaagac agaatggtag
     9541 acactgctag tggtttgaaa gaacaggtta aagatttgcc gaccaatgca agatatgcag
     9601 tatatcaagg aaaatccaaa gtaaaagaga atgtccgtga tttaaccagt agtatttctc
     9661 aaaccaaagc ggacagagcc agtggacgca aggaacagca ggaacaaagg cgaaaaacca
     9721 ttgcgaagcg tcgctctgaa atggaacagg tcaaacagaa aaaacagcct gcttcttctg
     9781 ttcatgaaag accgactaca agacaagaac aatatcatga tgaacagacc tcaaaacagt
     9841 ctaatattca gacttcatat aaggaatctc aacaagccaa acaagagcgt ccagcagtta
     9901 agtccgattt ttcaagtcca aaagtggaac gccaaggcaa taccgttcaa gaaaaaaccg
     9961 ttcaaaagcc agcaacttca accactacag cagatagaac ttcacaacgt ccaatcacaa
    10021 aagaacgtcc gtctactgtt caaagagtac cactacaaaa tacaagaagt agaccaccaa
    10081 tcaaaaccgc caccattaag aaagtcggta agaaaccatg aagttgaaaa ctttagtgat
    10141 tggtggttct ggattattct tgatggtctt ctcactgctt ctgtttgttg ccattttatt
    10201 ttcagatgaa caggacagcg gaatttccaa tattcattat ggaggtgtga atgtttccgc
    10261 agaagtgctg gctcataagc ctatggtaga aaaatatgcc aaagaatatg gcgttgaaga
    10321 atatgtcaac atacttcttg cgattataca ggtggaatcg ggcggtactg cggaagatgt
    10381 tatgcagtcc tcggaatccc tcggtcttcc acctaattca ttgagtacag aagaatccat
    10441 taagcaaggt gtgaagtatt tcagtgaatt attagccagt agcgaaaggc tcagtgtaga
    10501 tttagaatcg gttatccagt cctacaatta tggtggtggt ttcttagggt atgtggctaa
    10561 tcgtggaaat aaatatacct ttgaactggc tcaaagtttc tcaaaagagt attcaggtgg
    10621 cgaaaaagtg tcttacccca atcccatagc catacctatc aatgggggct ggcgatacaa
    10681 ctatggcaat atgttttatg tgcaactggt aacgcagtat cttgtcacaa cagagtttga
    10741 tgatgatacg gtacaagcca tcatggacga agcactgaaa tatgagggct ggcgatacgt
    10801 ttacggtgga gcttccccga ctacttcttt tgattgtagc ggactgacac aatggacgta
    10861 tggaaaagct ggaattaact taccacgaac cgcacaacag caatatgatg tgacccagca
    10921 tatcccacta tcggaagcac aagctggcga tttggttttc tttcattcta cctataacgc
    10981 tggctcttat attactcatg ttgggatata ccttggcaat aaccgtatgt ttcatgcagg
    11041 cgacccaatc ggttatgccg acttaacaag cccctactgg caacagcatt tagtgggagc
    11101 aggacgaatc aaacaatgag aaaggaagat ttaatgatga aatttagaaa aaatcagaat
    11161 aaagaaaaac agataccaaa ggaaaagaaa cctcgtgtct actataaggt caatcctcat
    11221 aaaaaggttg tgattgcctt gtgggtactt ttagggctta gtttcagctt tgcgatattc
    11281 aagcacttta cagctataga tactcatact attcacgaaa caactatcat agaaaaggaa
    11341 tacgttgata ctcatcatgt agaaaatttt gtagagaact ttgcgaaagt ctactattca
    11401 tgggagcaat ccgataagtc cattgataat cgaatggaaa gtctaaaagg ctatctgaca
    11461 gatgaacttc aagctctcaa tgttgataca gtacgcaaag atattcctgt atcgtcttct
    11521 gtaagaggat ttcagatatg gacggtagag ccaactggcg acaatgagtt taatgtaacc
    11581 tacagtgtag accagctcat tacagaggga gaaaatacaa agaccgtcca ctctgcttat
    11641 atagtgagtg tctatgtaga tggttctgga aatatggtac tggttaagaa tccgaccatt
    11701 accaacatac ctaagaaatc aagttataaa ccaaaagcca ttgaaagtga ggggacggtt
    11761 gattccatta caaccaatga aatcaatgag tttttaacga cgttcttcaa gctctatcct
    11821 acagcgacag ccagtgaact ttcctactat gtgaatgacg ggatattaaa accaatcgga
    11881 aaagagtaca tctttcaaga actggtaaat cctattcaca atcgtaagga taatcaagtc
    11941 acggtatcgc tgacagtgga gtatatcgac cagcagacca aagcaacgca ggtatctcaa
    12001 tttgatttgg tacttgaaaa gaacgggagt aattggaaga ttatagaata acaaatattg
    12061 gtacattatt acagctattt tgtaatcacg tactctcttt gataaaaaat tggagattcc
    12121 tttacaaata tgctcttatg tgctattatt taagtatcta tttaaaagga gttaataaat
    12181 atgcggcaag gtattcttaa ataaactgtc aatttgatag tggaaacaaa taattggatg
    12241 tcctttttta ggagggctta gttttttgta cccagtttaa gaataccttt atcatgtgat
    12301 tctaaagtat ccggagaata tctgtatgct ttgtatgcct atggttatgc ataaaaatcc
    12361 cagtgataag agtatttatc actgggattt ttatgccctt ttgggctttt gaatggagga
    12421 aaatcacatg aaaattatta atattggagt tttagctcat gttgatgcgg gaaaaactac
    12481 cttaacagaa agcttattat ataacagtgg agcgattaca gaattaggaa gcgtggacag
    12541 aggtacaacg aaaacggata atacgctttt agaacgtcag agaggaatta caattcagac
    12601 ggcgataacc tcttttcagt ggaaaaatac taagataaac atcatagaca cgccaggaca
    12661 tatggatttt ttagcagaag tatatcgttc attatcagta ttagatgggg caattctact
    12721 gatttctgca aaagatggcg tacaagcaca aactcgtata ttgtttcatg cacttaggaa
    12781 aataggtatt cccacaatct tttttatcaa taagattgac caaaatggaa ttgatttatc
    12841 aacggtttat caggatatta aagagaaact ttctgcggaa attgtaatca aacagaaggt
    12901 agaactgcat cctaatatgc gtgtaatgaa ctttaccgaa tctgaacaat gggatatggt
    12961 aatagaagga aatgattacc ttttggagaa atatacgtct gggaaattat tggaagcatt
    13021 agaactcgaa caagaggaaa gcataagatt tcataattgt tccctgttcc ctgtttatca
    13081 cggaagtgca aaaaacaata tagggattga taaccttata gaagtgatta cgaataaatt
    13141 ttattcatca acacatcgag gtcagtctga actttgcgga aaagttttca aaattgagta
    13201 ttcggaaaaa agacagcgtc ttgcatatat acgtctttat agtggcgtac tgcatttgcg
    13261 agattcggtt agaatatcgg aaaaggaaaa aataaaaatt acagaaatgt atacttcaat
    13321 aaatggtgaa ttatgtaaaa tcgataaggc ttattccggg gaaattgtta ttttgcagaa
    13381 tgagtttttg aagttaaata gtgttcttgg agatacaaag ctattgccac agagagagag
    13441 aattgaaaat cccctccctc tgctgcaaac gactgttgaa ccgagcaaac ctcaacaaag
    13501 ggaaatgtta cttgatgcac ttttagaaat ctccgacagt gacccgcttc tgcgatatta
    13561 tgtggattct gcgacacatg aaatcatact ttctttctta gggaaagtac aaatggaagt
    13621 gacttgtgct ctgctgcaag aaaagtatca tgtggagata gaaataaaag agcctacagt
    13681 catttatatg gaaagaccgt taaaaaaagc agagtatacc attcacatcg aagttccacc
    13741 gaatcctttc tgggcttcca ttggtctatc tgtagcaccg cttccattag ggagcggagt
    13801 acagtatgag agctcggttt ctcttggata cttaaatcaa tcgtttcaaa atgcagttat
    13861 ggaggggata cgctatggct gtgaacaagg attgtatggt tggaatgtga cggactgtaa
    13921 aatctgtttt aagtatggct tatactatag ccctgttagt accccagcag attttcggat
    13981 gcttgctcct attgtattgg aacaagtctt aaaaaaagct ggaacagaat tgttagagcc
    14041 atatcttagt tttaaaattt atgcgccaca ggaatatctt tcacgagcat acaacgatgc
    14101 tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa aataatgagg tcattcttag
    14161 tggagaaatc cctgctcggt gtattcaaga atatcgtagt gatttaactt cctttacaaa
    14221 tggacgtagt gtttgtttaa cagagttaaa agggtaccat gttactaccg gtgaacctgt
    14281 ttgccagccc cgtcgtccaa atagtcggat agataaagta cgatatatgt tcaataaaat
    14341 aacttagtgt attttatgtt gttatataaa tatggtttct tgttaaataa gatgaaatat
    14401 tttttaataa agatttgaat taaagtgtaa aggaggagat agttattata aactacaagt
    14461 ggatattgtg tcctgtatgt ggaaataaaa cacgattaaa gataagggaa gatactgaat
    14521 taaaaaaatt ccccctctat tgtccgaaat gcagacaaga aaatttaatt gaaataaagc
    14581 agttcaaagt aactgtgatt acagagccag acgcaaagac gcagagccga taaaatgaga
    14641 ttaatacaat ctcattttat cggctctttc cgttatgtat ggattctttt aattagtctt
    14701 cgatgtttct tgcttcgttg ataccgctgg ctaaagattc cattaaggat agttctttgt
    14761 ctgtaaagct atccatgtat ttctctatct gtaatcgtcg ggtgcttttt accaagttat
    14821 tagcaggtaa gaaaaattca tcaacggaaa catgaagtaa cgatacaagg tcataaagaa
    14881 cttgtatgct ggggtgttgc cctttatttt caatattagt taagtaccgt gggtcaattt
    14941 caatcaatgc tcccacttgt tcacgagtta aacctcgttt caatcgagct tctttaatgg
    15001 ctaaaccaaa ggctctaaaa tcatatttat cttctttttt acgcatagta gaccacctct
    15061 atacatttta ttgttcctac tgaattaaaa acaggtatag aaaaacgtgt tatatggttt
    15121 ataggtttat atttaataaa aagcactact aaacgccaat aaaaaaaacc gttatatggt
    15181 agtgctattt acgctgttaa aatattgtat attacttcca aatggcggtt tgttggaggt
    15241 caacgtcgcc atgaagtaca tcatatacaa taaatttcct tacattgggt tcttgtcaaa
    15301 aaaagtcgtc tatctgcaat agataagtac gtccaccaat gtggttttat aaatcatata
    15361 gatagaataa cagaagcatg taaacagaga aataaatctg tttatatgct tttttggcta
    15421 ttcagaactt ttttacaaag tttatttatc agtaatgcaa caaatccccc tttcacattg
    15481 ggactaagag tgaaaggaga taaacgagca aggctcactt cctttcctag acagaaaggg
    15541 ggtgagaaac atgaaaccat cttcttttca gaccacaata gaaaatcagt ttgactatat
    15601 ctgtaaacgt gctatggaag acgagcgaaa gaattatatg ctttatcttt caaggattgc
    15661 aaagcgtgag gtgtcctttt cggatgttgg cgattatctt gttagccagt ttgcgacaac
    15721 agataactat tcaactgact ttcagatttt tacactcaat gggttatcag taggcgttga
    15781 aaatgatttg ttgagtgaag cattacgtga gttgccagac aagaaacgtg aaattctact
    15841 gctgttttac tttatggaca tgagcgattc agaaattgca gacctgttga aattgaaccg
    15901 ttctactgtc tatcggcata gaaccagtgg actagcctta attaaaaagt ttatggagga
    15961 atttgaagaa tgaaaacaca atatcctatg attccctttc ctctcattgt aaaggcaaca
    16021 gatggcgata ccgaagcgat taaccagatt ctacatcatt acagagggta cataacgaag
    16081 cgttccctac gacttatgaa agatgaatat ggcaatcaaa gtatggtcgt tgatgaagtc
    16141 ttacgtggaa gaatggaaac cagactgatt acaaagattt tgtcatttga aattaagtaa
    16201 tatcctctct cctttcgtgg aagcgtgcta aaccattcca cgcttcccga acagggaggt
    16261 ttgttattcc accaaagcat attgagcttt caatgtgttt tgataggcta acgagccatt
    16321 gttctttgaa aactgaataa aagtaatcga atacgtttcg ataagaaaag agccaacgga
    16381 actaaccgcc atgacctatc ttataaagat agcgagcgat tcatgttagt gatccgagaa
    16441 gcaatcttta gcaggattgc ctgcaacgac attcttatcg tgataatgat actcccatac
    16501 agtcaatagt ccgagcgtga taaaaccgtc gcaggcaatg agtatggcta catgagaacc
    16561 atgcaggggt ggaactcccg tgagctttgc taaagctgtt cgattgctgg taaaacaact
    16621 tttatgaaat ccaaataagt gatttggaaa ggaggatttt atgaagcaga ctgacattcc
    16681 tatttgggaa cgttataccc taaccattga agaagcgtca aaatattttc gtattggcga
    16741 aaacaagcta cgacgcttgg cagaggaaaa taaaaatgca aattggctga ttatgaatgg
    16801 caatcgtatt cagattaaac gaaaacaatt tgaaaaaatt atagatacat tggacgcaat
    16861 ctagcgtcgc caaagggtct tgtatatgat aaaatagtat taagtcgtat caaggctctt
    16921 tccataaagg aaaggagcaa atgccatgtc agaaaaaaga cgtgacaata aaggtcgaat
    16981 cttaaagact ggagagagcc aacgaaaaga cggaagatac ttatacaaat atatagattc
    17041 atttggagaa ccgcaatttg tttactcgtg gaaacttgtg gctacagacc gagtaccagc
    17101 aggaaagcgt gattgtatct cacttagaga gaaaatcgca gagttacaga aagacattca
    17161 tgatggtatt gatgttgtag gaaagaaaat gacactctgc cagctttacg caaaacagaa
    17221 cgctcaaaga ccaaaggtta gaaaaaacac tgaaactgga cgcaaatatc ttatggatat
    17281 tttgaagaaa gacaagttag gtgtaagaag tattgacagt attaagccat cagacgctaa
    17341 agaatgggct attagaatga gtgaaaatgg ttatgcttat caaaccatca ataactacaa
    17401 acgttcttta aaggcttcat tctatattgc tatacaagat gattgtgttc ggaagaatcc
    17461 atttgacttt caactgaaag cagttcttga tgatgatact gtccctaaga ccgtactaac
    17521 agaagaacag gaagaaaaac tgttagcctt tgcaaaagct gataaaacct acagcaaaaa
    17581 ttatgatgaa attctgatac tcttaaaaac aggtcttcgt atttcagagt ttggtggttt
    17641 gacacttcca gatttagatt ttgagaatcg tcttgtcaat atagaccatc agctattgag
    17701 agatactgaa attgggtact acattgaaac accaaagacc aaaagtggcg aacgtcaagt
    17761 tcctatggtt gaagaagcct atcaagcatt taagcgagtg ttagcgaatc gaaagaatga
    17821 taagcgtgtt gagattgatg gatatagtga tttcctcttt cttaatagaa agaactatcc
    17881 aaaagtggca agtgattaca acggcatgat gaaaggtctt gttaagaaat acaataagta
    17941 taacgaggat aaattgccac acatcactcc acatagtttg cgacatacat tctgtaccaa
    18001 ctatgcaaat gcaggaatga atccaaaggc attacagtac attatgggac atgctaatat
    18061 agccatgacg ctgaactatt acgcacatgc aacattcgat tctgcaatgg cagaaatgaa
    18121 acgcttgaat aaagagaagc aacaggagcg tcttgttgct tagtagtaca aatgaattta
    18181 ctacttattt accacttctg acagctaaga catgaggaaa tatgcaaaga aacgtgaagt
    18241 atcttcctac agtaaaaata ctcgaaagca catagaataa ggctttacga gcatttaaga
    18301 aaatataaaa agataattag aaatttatac tttgttttta ttaaaaagca gcaaactata
    18361 aactagtagg ttccacacta aatgtagccc catactgccc cacaagtccg atttatagcg
    18421 taccatccct aaaaacattc ccaatgaaac atataaacac caagctagaa tggttcctgg
    18481 atgatgagct aaggcaaata aaacacttgt caaagcaact cgaatatcta attttctaac
    18541 caagttccat aaaatttctc tatacaaaaa ttcttcaacc atactcgcat tgattaagaa
    18601 caataaaaat gaaaaccaag gaacttgatg ttgaagccca attaagtttg cttgatttgt
    18661 gctttcttga gcatgaatca gactaaaata tagactgata atcagtaggc taacgaatcc
    18721 aataccaatc cactttatcc tagtttccat attgaccttg gccacttgtt ttcgttgacc
    18781 atacatccat aaaaaagaaa tgagcgacgc tccatagata atctgtagta tagttaactc
    18841 accgatacaa agaaatttca gtaagtataa ggataccaat aggacattta cttgttggaa
    18901 tatataaact ggaattattc ttttcatagt tacctccgaa ataaatcttc ataatctaaa
    18961 tctaatacct gcacaatcct ctctacccat ggactttgag gcattcgttg ttccatcttg
    19021 tagtgacgaa tcttttgata caaacgattc aattcacttg gatagtgaaa ctctcccgca
    19081 aacatttttc tggttaactc aatccagctg atatttcttt cagccaaaat aatggacaag
    19141 ttctcccaaa atcgttcagc catattgctt ctcctttagt tagataaata atgtgtttgt
    19201 gccatgtaaa tcaattgttt cgtatctctt ggtaataaag ccctagcttc ctccaaattt
    19261 agatttggat aaactcgctt atttgaaacc gcaagaggaa gtctgatggt tagttcagga
    19321 ttttttaata tcatttcaat gaaatccgtt agtcttaaat tgtcacggtt cttaaatcgt
    19381 aataaattag gagataaaaa ctcaaaacaa tctgaagaat agctcatcat ctcaattaat
    19441 ttatcccttg tcatttcaga aatcgaatga caggatacct caatgccata gttttggaag
    19501 aattctaaaa gaagttgatt tctatggtta tttttactta gatagagatc aatcatgtga
    19561 gacctcccaa agattcggtt ccatttgata ttctgagacg attaaggaat ctaataaatt
    19621 ggagaagtta attgatttct tgtcttcatc ataagctttt acagttactt gggttgtaag
    19681 tattccctct tttccctcgg ctcgatagcc ttgcccatat aaaacaaaaa caagattatg
    19741 attatcatct ataaaggcat cagctccgtt ctttatatcc tgactttcaa ggaattccat
    19801 aatgttttga agataggatt cgtaaaatag ggggtaattg tgttttttat ggtaataatc
    19861 taaaaatgtc acctcaaact cacatggata attgggcatc aaaaatattt gttcatccaa
    19921 ctgcatcatt tctgcatcat gtaattctgt ttctaattca tcacaatata gtattgactc
    19981 tttatttagc gctttcatct ttttcctcta tttcttttaa tttttttgcg attgcggcaa
    20041 tcacaggaac agttacacta ttaccagctt gtttatagag ctgactatta ctagagactt
    20101 ttctagcagc ttcaaaagcc caatcaggaa agc
//
LOCUS       DAVBNZ010000039        18510 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000039 DAVBNZ010000000
VERSION     DAVBNZ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18510
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.039"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(1..365)
                     /locus_tag="VQ860_001456"
                     /pseudo
     CDS             complement(1..365)
                     /locus_tag="VQ860_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(441..875)
                     /locus_tag="VQ860_001457"
     CDS             complement(441..875)
                     /locus_tag="VQ860_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3119872.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(951..1801)
                     /gene="rfbD"
                     /locus_tag="VQ860_001458"
                     /pseudo
     CDS             complement(951..1801)
                     /gene="rfbD"
                     /locus_tag="VQ860_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1867..2916)
                     /gene="rfbB"
                     /locus_tag="VQ860_001459"
     CDS             complement(1867..2916)
                     /gene="rfbB"
                     /locus_tag="VQ860_001459"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET3119873.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2926..3522)
                     /locus_tag="VQ860_001460"
     CDS             complement(2926..3522)
                     /locus_tag="VQ860_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET3119874.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3523..4380)
                     /gene="rfbA"
                     /locus_tag="VQ860_001461"
     CDS             complement(3523..4380)
                     /gene="rfbA"
                     /locus_tag="VQ860_001461"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET3119875.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELAITDVNKVYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
     gene            4594..5900
                     /locus_tag="VQ860_001462"
                     /pseudo
     CDS             4594..5900
                     /locus_tag="VQ860_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6188..6370)
                     /locus_tag="VQ860_001463"
     CDS             complement(6188..6370)
                     /locus_tag="VQ860_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119876.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(6586..7818)
                     /locus_tag="VQ860_001464"
     CDS             complement(6586..7818)
                     /locus_tag="VQ860_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3119877.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(7847..8917)
                     /gene="gla"
                     /locus_tag="VQ860_001465"
     CDS             complement(7847..8917)
                     /gene="gla"
                     /locus_tag="VQ860_001465"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET3119878.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(8985..10154)
                     /locus_tag="VQ860_001466"
     CDS             complement(8985..10154)
                     /locus_tag="VQ860_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET3119879.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(10340..11644)
                     /locus_tag="VQ860_001467"
     CDS             complement(10340..11644)
                     /locus_tag="VQ860_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET3119880.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(11761..12915)
                     /locus_tag="VQ860_001468"
     CDS             complement(11761..12915)
                     /locus_tag="VQ860_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3119881.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(12912..13463)
                     /locus_tag="VQ860_001469"
     CDS             complement(12912..13463)
                     /locus_tag="VQ860_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET3119882.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(13456..14592)
                     /locus_tag="VQ860_001470"
     CDS             complement(13456..14592)
                     /locus_tag="VQ860_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3119883.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(14733..15398)
                     /gene="cpsD"
                     /locus_tag="VQ860_001471"
     CDS             complement(14733..15398)
                     /gene="cpsD"
                     /locus_tag="VQ860_001471"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET3119884.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTISVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGNLFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(15408..16100)
                     /gene="cpsC"
                     /locus_tag="VQ860_001472"
     CDS             complement(15408..16100)
                     /gene="cpsC"
                     /locus_tag="VQ860_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET3119885.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(16109..16840)
                     /locus_tag="VQ860_001473"
     CDS             complement(16109..16840)
                     /locus_tag="VQ860_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET3119886.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(16842..18287)
                     /locus_tag="VQ860_001474"
     CDS             complement(16842..18287)
                     /locus_tag="VQ860_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3119887.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         5961 a         3782 c         2708 g         6059 t
ORIGIN      
        1 aggaccagat gtccgtcttt caaaatagtc ttaaaggttt cttcatactt gaggctgtat
       61 tcaattgccc ttcctagttt tgaacctgct aaaactgact gacgccggca ccaagcaaag
      121 aagtcttcca ttaggggctg gagatgttct tgacgtttct gtagtcgttc atcagctggc
      181 aaagcctccc agtctctttc caaggaaaat aactgatcac aataagctaa acctttagct
      241 cctaaggatg atttatccgt ttgcttgggg ggcgcttcaa aaaacttcct tctcacatgt
      301 gcccaacatc caacaagttc agcttcttcc agttgacgat aagcttctag cggttcgcag
      361 tttaccaagc ttagcgtcgc cttgctccta aaccttggac tgctatcgca taggcagaac
      421 tagaggacta aagtcctaag ttactgccgc aacatatcac aatgcacata gccagaataa
      481 tctcctagga attcttgtac tactaaacca ctccgacgct gatcatggtg gtacagcgtg
      541 attgcttgat tctcagcttt cccagacaaa aaagtccaat agtaggtcag atggctatca
      601 ctctctagaa cccgataaga ggtttcatcc gcatgaagaa gaggttgttc taacaacttt
      661 tctcgtaaaa ggttataaag ggactctaaa tagtattgac ttgccttgat atgccaatta
      721 gagatttcct tacgtgtgat tggtaaaccc atcctagccc aatcttcttc ttggcgataa
      781 ttgggtacct tcagattaaa cttctgatgg atggtgtgag cgataataga aactgagcca
      841 aagctatgca ccaaagagac cagcaccaac aacaagataa ttgtacatct taagctcctt
      901 tggagttcat tatctgcctc ttttattaga ctagaaaatc attctactac ttatctcact
      961 tcttgtttgt aaaattcttg caatgcatct tgccaagttg gaataacaaa tccagtagct
     1021 ttggctttgg ccaggctcat cgttgagttt agcggacgtt gagctttggc tggaaattga
     1081 ctggatctac tggcttgact tcgacatctg tatctttcaa aatttcaact gcaaaatcat
     1141 accatgttgt gtcttctgtc gcatcatttg acaaatgata ataaccaaat tccttacgat
     1201 tttcagctag gtagatcatg aattcagcca aggtacgagt ccaagtcgga cgaccgtact
     1261 ggtcatttac aactgttaaa gtcttatgag ttttcgcaag attttgcatg gtaaaaacga
     1321 agtttttgcc ataatttcca aatacccagg cagtacggat aatatagaaa ttagacacat
     1381 gcttctcaac taactcttcc cccatacgct tagtgcgtcc atattctgtc tgtggatctg
     1441 gtcggtcatc aacttcccac tcttgtccaa ctggtttctt accgtcaaag acctagtccg
     1501 tagaaatata aactagagtt gcaccatgct tttcagatgc ttttgcgaca ttttttgtcc
     1561 ccatcacatt gatggcgaag tccaactctt ttccttcatc ctctgctgca tcaacagcgg
     1621 tgtaggctgc acaatggtag actaaagtcg gtttcacctc ttcaaaaact ttctcaacca
     1681 tttcttcatt ggtaatgtcc atctcagcca catctactgc cacgtattct tcattacgtt
     1741 catccaataa atagcgaagt tccgttccta attggccatt tgcccctgta attaaaatca
     1801 tctctagacc tttctaatat gtaactcttc ccaatatagc aataaaaagc agcgatttcc
     1861 tgctttttat actgtaataa tctcctgagt cttagcataa ttggcttcaa cagcttcttt
     1921 ttctgctttc caccattctt ggttatctgt ataccacttg attgttgcct tgagcccagc
     1981 ttcaaagttg gtaaattcag gtttccaccc caactcatca cggagcttgc tggcatcaat
     2041 cgcatagcga aggtcatgtc ctgcacggtc agtcacatga tcataggcat ccgtagcttg
     2101 tcccatttcc ttaaggataa gttccaaaac ttccttattg ttcttctcac catcagcccc
     2161 aatcaagtag gtttcaccga tttgcccttt tgtcaagatt gtccaaactc ctgaagaatg
     2221 gtcattggta tgaatccagt cacgaacgtt cttaccttca ccgtaaagtt ttggcttaat
     2281 tccacttagg atgttagtaa tctgacgtgg gatgaatttt tcgatatgtt gataaggacc
     2341 gtagttattt gaacagttgg aaatcgttgc cttgactcca aaagaacgca cccaggcttt
     2401 gacaatcaag tctgatgcgg ccttggttga tgagtacgga gagcttgggt tgtattttgt
     2461 ttcagcagta aatttctcac ctggtccttc accatgacct ggcaaatctt ctcgtaaagg
     2521 gagatcccca taaacttcat ctgtcgatac atggtggaag cgaatatcat acttacgagc
     2581 agcttctaaa agagtataga ttccaatgaa gttagtatga ataaatggcg atggatcatt
     2641 gagcgaatta tcattgtggc tttccgctgc ataatgaacg atagcatctg cttgagcaac
     2701 caacttgtct accaactccg catcagcaat gtcaccaaca actaactcaa cacgattgcc
     2761 taaaatttcc tcaatattcg cgcggtttcc agcataagtc aacttatcta ggactgtcac
     2821 gtgaacatct ggaaagttct cgtaaacata atggacaaag ttagaaccga taaagccagc
     2881 tccacctgtc acgataatat ttttgtattc agtcatattc tttccttatt ccaaatcttc
     2941 ttttttcaaa ggcttcacgt ccttaagtag gggatgatgt ttgtctgctt cagatacgtc
     3001 tgcttcttcc agattttccc attcaatacc aaggcttgga tcagcgtagt tcacaaaggc
     3061 atacttgggt ttgagttcaa gagcccagta atcattgacc agatagctat atgacactgt
     3121 atctgataaa acttggaagc cattagctac gcctcgagga acaaagattc ccttgcttgc
     3181 atcaattact gtctgatagg tattcccaaa ggtttcaccc tcgcgtagat caacccaaga
     3241 acccagaact ttccctccat ctgctacaga gatgtactta tcccaaggct ctgcgtggag
     3301 gcctcgaagg acatttttac gtgagaagga tacattgttt tgcaattttc cttctgcaaa
     3361 gaaagactct ggaaatccaa gtggaagcac tttttccttt tggaaatttt ctttaaacca
     3421 gccacgatta tctccatgaa cggggatatc aaactccaac atgcctggaa tagcttcaac
     3481 cttgcgtgcc gcaagcgtct taccgaaaaa attatctgtc atctatgctt ctccaatcaa
     3541 acggagcaga tactgtccgt attcattttt cttaagtggt tgggctaagg ccaatacatc
     3601 ttctcgactg atatagccca tacggtaagc aatttcttct aagtttgcta cctgaacatt
     3661 ttgcatccgt tgcactgttt cgatgtactg tgaagcctct agtaaacttt catgagttcc
     3721 agtattcagc caagcaaagc cacgtcccat aagctcaaca gacaaatcac cacgatctag
     3781 gtaaaccttg tttacatctg taattgccag ttcaccacga gggcttggtt taatactctt
     3841 ggcaatttcg acaacatcgt tatcatagaa atacagtcct gtcactgcat agttggagcg
     3901 aggatactcc ggtttttctt ctatggaaat agcattcatg tctgtatcaa actcaaccac
     3961 accaaaacgc tctggatcct tcacttggta gccaaaaaca gtcgcacctt tctctttctt
     4021 ggctgctttt tgaagcattg tgctcagacc aggaccatgg tagatattgt cgcctaaaat
     4081 caaggcaacg ctatcgtcag aaataaactc ttccccaatt gccaaaccat ctgtacttgg
     4141 ttgctctgca taagaaagtt tgatcccaaa ctcagatccg tcttgaagaa gctcttgaaa
     4201 tcgatgtaaa tcctgtggag tggaaataat caaaatatcc ctaatcccag ccaacatcaa
     4261 tgttgaaagt gggtagtaaa tcatcggttt atcataaacc ggcataagtt gttttgacgc
     4321 agcgcgagtc aaaggatata aacgtgtccc cgaaccacct gctagaataa tacctttcat
     4381 agtagggtac ctttctttgt tattttagag tcaattacta ttaattgtgt actgctctaa
     4441 aaagaaaaca atcatcccat gttttatatg gctctataat atttgtagtg ggtaaatccc
     4501 ttatagatat tatggagcct attttgttgt agaaaaaaag tcccatatga cctataatga
     4561 aaagcgacca aacaactcat tagaaagatt catatggaac aattacattt tatcacaaaa
     4621 ctgctcgata ttaaagaccc aaacatcaag attctagata tcatcaatat ggatacccac
     4681 aaagaaatta tcgctaagct ggattatgag gctccatctt gccctgattg tggaagtcta
     4741 atgaagaaat atgactttca aaaaccgtct aagatccctt atcttgaaac gactggtatg
     4801 cctactagaa ttctccttag aaagcgtcga ttcaagtgct atcactgttc aaaaatgatg
     4861 gtcgctgaaa cttctatcgt caagaagaat caccaaatcc ctcgtatcat caaccaaaag
     4921 attgctcaaa agttaattga aaagatttct atgactgata ttgcccatca gctttccatc
     4981 tcaacttcaa ctgttattcg taagctcaat gattttcact ttaaacatga tttttcttgt
     5041 cttcctgaga ttatgtcttg ggatgagtat gcttttacaa agggaaagat gagcttcatt
     5101 gcgcaagatt ttaacaatct caatatcatc actgttcttg agggtagaac acaagctatc
     5161 attcgaaatc actttcttcg ctacgataga gttgtccgat gtcgcgtcaa aatcattact
     5221 atggatatgt ttagccctta ctatgacttg gctaaacagt ttcgctttca aatttctagg
     5281 ctcaggctga aacagtctcc cagactgttt cactcccgaa tgctaaaatc gtgttggatc
     5341 gctttcacat tgtacaacat cttagccgtg ctatgagtcg tgtgcgtgtt caaatcataa
     5401 atcagtttca tcgaaaatcc catgaataca aggctatcaa gcgctactgg aaactcattc
     5461 aataggatag tcgtaaactg agtgataaac atttttatcg tcctactttt cgtatgcatt
     5521 gaaccaataa agagatttta aacaagcttt tgagttattc ggaagacttg aaacaccact
     5581 atcaactcta tcagctcttg ctttttcatt tccagaataa ggaaccagag aaatttttcg
     5641 gacttattga ggacaatctt aagcaggttc atcctatttt tcagaccgtc tttaaaacct
     5701 tcctcaaaga taaagaaaag attgtcaacg cccttcaact acactattct aacgccaaac
     5761 tggaagcgac caataatctc atcaaactta tcaagcgcaa tgcctttggt tttcgaaact
     5821 ttgaaaactt caaaaaacgg attttcatcg ctctgaacat caaaaaagaa aggacgaaat
     5881 ttgtcctttc tcgagcttag ctgacttcaa cccactacag ttgacaaaga gcctaaaaat
     5941 tcacttactt catattacat ttagcatgaa atgaaataag cgaattctac tttgtttgca
     6001 tacaattaaa aatcaattcc taaggatgtt ttaaataact gtgtaaaagg cataatttca
     6061 ccatttctta gtttttcaat gctaaattac atagtaactg gagagctatt agaaatctct
     6121 aacttcctca tagttaaaaa atgacaatga gatacttatt gatttcaatt cattaacaga
     6181 atacgaacta gacaagtgag ttcgtctcct taacaaacac ttccaagcgt ttactttcct
     6241 cattcagtcg tcgtaatcta caacttacat catcagataa gtcatactca ccatttagaa
     6301 tagatagaat atgttgtttt tcttcttcag tcttctcttc aataagcaca tttttaaaaa
     6361 ttactgccat tatcagcacc tcacttcgaa ggaatatatg caactatatc ctattaagtc
     6421 aatctctact gacaaaagaa gtatatttac ttcactaagt gcgagcgaga atatagaaat
     6481 atctttattg ttttagatga gttgtcgcta tcctccagct agtttttaac tattctatca
     6541 ttcaaatgat atagattatt agggactaga aatatacaaa ttgatttaat ctctcttaaa
     6601 aatatcccta gtataaactt tacccctcac atcttctaaa gtctcatcaa aacgatttgc
     6661 aacaatcact tgactagatt tcttaaatat ttcaaaatca ttaactactt gactaccata
     6721 gaaagtagta ccactttcaa gagttggttc gtaaataata atagtaacac cttttgcttt
     6781 caaacgcttc ataatacctt gaatagaaga ttgtctaaaa ttatctgaat tacttttcat
     6841 tgttaaacga taaattccta caacaatctc tttttcttta tctggtttat agaaatcatt
     6901 gcctacataa gatccagcaa gatctaaaat acgatctgca atataatctt ttcttgtccg
     6961 attactttgt actatagctg ttatcatttc ttgtggaacg tcagaataat ttgcaagaag
     7021 ttgcttggta tctttaggaa gacagtaacc cccataacca aaagaaggat tattgtagtg
     7081 agaacctatt ctcggatcta aacaaactcc atcaataatc gcttgagtat ctagtccttt
     7141 catctcagaa taagtatcta actcgttaaa ataggaaacc cggagggcaa gataggtatt
     7201 agcaaaaagt tttactgctt cagcttctgt aaaatccata tacaatgttt caatattttc
     7261 tttcactgca ccttcctgaa gcatttttac aaaaatttca gcagacttta ccaaatcttt
     7321 atcatcttta tctgtaccta taataattcg actcggatat aggttatcat ataacgcttt
     7381 tgactcccgt aaaaactcag gactaaacat aatattgtct gtaagaaatt tcctccgtac
     7441 tgactttgta tatccaacag gaacagtact tttaattatt ataattgcat caggattata
     7501 tttcataact gcttcaatga cagcctcgac tgaagatgta tcgaaaaaat tttttttcgg
     7561 atcataatta gttggagccg caataactat aaaatccgca ttctcatatg cttcctctgc
     7621 attcaatgta gctacgagat tcaattcttt ttccgcgaga tatttttcta tataatcgtc
     7681 ttggataggg gacttctttt tattgattaa ctcaactttc tcaggaatga tatctacggc
     7741 aacaacttga tgatgttgag ccagtaagat tgcaatagat aatccaacat atcctgtacc
     7801 tgctactgct attttcataa ttttttcctt tctcaaaaca ctctcgttat acattatagt
     7861 agtctttata ccactctgca aactttctca aaccttctcg taaagaagtt tttggtttaa
     7921 aaccaaaatc tctctctaaa tcacttgtat ctgcataagt aacaggaaca tcgcctggtt
     7981 gcataggaac taatttttta tgactatcaa aatcataatt ttccggcaaa actcctgcct
     8041 tgattagctc ctgttgaaga acatccacaa aatctaacaa attttcgggt ttactattcc
     8101 caatattgta cactttatat ggggctaacg gtaaattatc agatcccact agtttcttcg
     8161 gagctgattg catgaccctt actatcccct caacgatatc atctatataa gtaaaatctc
     8221 gtttacaatt accatgatta taaatctcaa tatcggaacc acttcgcaat ttatctgtaa
     8281 atccaaaata ggccatatct gggcgcccag caggaccata aactgtaaaa aagcgtaagc
     8341 ctgtcgaagg aatattgtaa atctttgaat aagcatacgc ttgaagttca tttgtttttt
     8401 tagtcgcagc atatagtgaa ataggattgt ctaccttatc ttctgttgca aacgggattt
     8461 ttttatttcc accatatacc gatgaggacg atgcataaac taagtgttcc acaccaccat
     8521 catatatctc atacgaatga cgacaagctt ccaacacatt atgaaagcca acgatattac
     8581 tttctatata tacatctgga tttgtaatgg agtagcgtac tcctgcctgg gcagctagat
     8641 taacaacaat ctgaggatga taactcttaa aaatcttatt aataagcatt ttatctgcaa
     8701 tatcaccctt gataaatatc cagttttttt ctggataatc ctgaattagc ttattaagtt
     8761 gaagcaatcg ataatcttta agtgcaatat catagtaatc attcaaattg tccaaaccaa
     8821 tgattgtcat cgttccttct aattccaata atttcctaac cagatttgat ccaataaaac
     8881 cagctactcc tgtaattaga attgtttttc ctctcatatc ataatacctc ttgttatttt
     8941 tatattttca tccactaata cacattcttt aacaactatt ataatcaatt tctaagataa
     9001 tctataataa aaaacaaacc acatacagta taagagattg ctgatgctat cgcagctcct
     9061 gtaatttggt agttaggaat taagtaccag tttaaactta tatttatcaa agccgacaca
     9121 gataaaattt ttatagctac actctgttta ccctgagata tataaattgg ttgtaaaatt
     9181 ttaaagaaaa tcatcgataa gcttcctaaa aaaatgacta atgttatagg aaatgccttt
     9241 atataactgg aaccataaag gagcgtaatc gcaaattctc caaaagaaag aaatccaata
     9301 attaataaaa tcataaatag aaatgatact tttattgcat ttattgcttt atttttctca
     9361 aaagttcttt tagccgaatc accaaataaa atctctttaa atgagtctgg aaccatcaaa
     9421 aacatattag aaaacgtaac tgcgacactg tatataccta cattataact actagacatt
     9481 tgcttcaaca ttatgatatc aatactataa ttaaatgtaa ttaatagagt aagaatcata
     9541 gaaagaaatc caaacttata tatagtgaaa aattctttaa tactaatatg ttcaaaaact
     9601 gggaacatat tgtaatagta taaaaataaa atgatacgta aaaattcatt aatagcatat
     9661 accaaaaata ccatctctat agaaactaaa tgaaatagta acaacaatac tagcataacg
     9721 gaatatacta cgcttactcc taatacaatc ttattcctct ttatactatt ttctattact
     9781 gcaatcatag taagatttgt tctcataata gatagactgg acaaaactat tattacccca
     9841 ccataatcta tcggaacatc agctaaaact attattaaac ctattattcc aaacaataat
     9901 ccttgaataa aagttaaaaa aacaaattta ttctgatact cattagaatg attcctttta
     9961 aaggtcgagt aagcctgacc taaaccaact ccacctaaaa tataaaaaat ttctactaag
    10021 ttcattacat aggcataatc tccttttttt tcaacaccta atcccctatt aattataatt
    10081 gaggataaaa gtgttaataa gattaacaaa aatttactcg ttaaagcaaa ccaatatttc
    10141 ttagatagtc tcacttattt tctccgtatg ttaaatttta taacagtaaa tttaaaatta
    10201 tagtatattg aaatagaata tgaacaaaac gattagggaa tttaaagtaa tttataaaaa
    10261 ttctttagaa gctgcattgt actactccaa cttcaaacca ctatagtatc aaaaagtata
    10321 ccccaccttt ttaaataaac tactcaccac ccatttcatc caatggtgat atcaacacca
    10381 ttctattgat aaaaacaata accaatgttc ccaatatagc atatttaagt aatggagata
    10441 atatgttagc aaaatcagca cgagtagaat aaataaaaat aggtatcata tacagatata
    10501 tcagcatccc gtatatattt ctttgagcgt ttatataaag aaatctcatc aaaaagcctg
    10561 ttagcataaa aatcattaca attccaaagt atcctccatt cacatatccc tctcccacaa
    10621 gagtaaaacc atatttggtt gaatgtacgt ttggaaaaaa ggtgtccata aaccaagttt
    10681 gattagaata ccccgtatta taaaaaattc ttactatgtc attaaaaaaa gaacgacctt
    10741 cgaaataatt gcccatatta tgtaatatca gaatctgtaa attacgacta gctgatacaa
    10801 actcaccatc tagcaaatca aaccaaatat tatttgtatt tatagatgaa acttgcccac
    10861 ttaataaagt atatttaaaa actgcagata acggaatcag tagtgccgca agcggaacta
    10921 acattacaag ataaaaacgt tttattttgt gaaagtaaaa taatataatc acatcaagga
    10981 tgaataaagt aaacatataa tctctttccc ctgtaacgat agagaagaga cagataacta
    11041 tcgctgtgtt agtattacaa tttagtagtc tccatttttt agtactcaac tgtataaata
    11101 gctgatatgt atgaatgaga atcataaaat aaaccaaaga aaatactaac attatcacaa
    11161 tattggcacc tgaatatatt tcccctttat ttctaaaacc acttcctaat agatatataa
    11221 ttgctactgt tgtgataaac gtattcatat tattgagaaa taataaatag ttattgttat
    11281 ttaggtttat tttcctttcg cttaacacaa tggctttaga aggtagagtt aacaacaaag
    11341 ttgccaaagc cagccattgc atgaaaatca aatcttttgt ataaccatag tttatatact
    11401 ccattctata gagtagcggg taagaaatag aataaatagt aaagaagcta ctataccaca
    11461 catagggatg aaaaatatta aatttcacaa ttatcattgc cataaaactt aaaaaaatca
    11521 ttgaaaataa tggaattgta acatcattat tttcactgca taaaattaaa gtccctgaaa
    11581 aaactacacc tactagaagt attattttat tttttatatc atttgattgt agactaaact
    11641 tcatttactt ttttccttta actaataatt taaacgtaat gcgtattcaa aaatttgatt
    11701 ggctatgtag tcagttttta tagcatattt aatatatcga aacggatttt ccatcgcatt
    11761 ttaatctaaa ccatcagaat tatttaattc tcttctaatt tgagcaaaat agtcacttct
    11821 gcgtttattt aatacactcg aaagaaattt ttttgagaat tcaaactgtt ttatcaccat
    11881 cttttcctta tccatactaa taaaatctat aatagatccc gcaatcgctt gtgaagagga
    11941 tggagtaaat agacaatgtg gccccagcaa ctctggaatt cctgctttat tagaccctat
    12001 acaagggcaa gcacggctca tagcttcaat taccgcacga ggtaaccctt cttgtaaact
    12061 tggttgtata tataaatcaa ctttatccaa atactcataa atttgtgatg tagtcaattc
    12121 ccctaaaaaa tggattctat tcgctactcc caattcctct gctttctttt ttaagaaact
    12181 ttgatcacca tcacctgcta aataataatc caacaaaata ccttgtattt ctaatctctt
    12241 cattgcttcc aatacaaatc tatggccctt ggctcgtaca ttcacagatg ctgttgtcat
    12301 tattgaaatt ttttgaggat taaatttttt caacttataa agacggctct tcaaagatct
    12361 attctctaca gaggtaatat taacatttga agcaacgata ttagatttaa tattaggata
    12421 tctatcttgt aaatattttt ctgtcacgta tatgcaataa ttagcgtttt ttacaattga
    12481 tttagttttg gcgtatatat atggagctaa taattttccc tttaaactat gataccagta
    12541 agaatcccaa gcatccccca ttatttctgt cagatacggc ttacctatct tcaatgcgta
    12601 gtctgcagtt tttgatccaa ttatagacgg aatacgaaca actattaagt cgctatcaat
    12661 cattccttca ataatcttat ttttattttg accaaataga acctgatgta gaccttctat
    12721 agggataaat ttattaataa agttcgcttt atgatatcct tcagggtatg attccacctt
    12781 ctcataacga ctacatagta caatctctcc aaatgcttta gcatagcgct cataaataaa
    12841 ataagctttc ggttttaaat atatttcatt tttatagatt gtacatctaa attcagtcgc
    12901 tataaatact ttcataattt catctccctt gataaacgtt tctgaataaa tatagtatca
    12961 gctggaatat cctttgttac aacacttcct gctgcaacca cactattctc accaatactc
    13021 actcccttca agacaatgct gttagctcca atccaaacat tttctccaat cataactggg
    13081 gccgtcttaa atttttttgc tttcaatcca cctggaacac taacatcata gtcatgatca
    13141 tatataagta ctccaggacc acattttact ccagatttaa tatctatgta tttacgacaa
    13201 gctatcatac aattattact caaaaataca tcatcagaaa tcttgagttt tgctcctttt
    13261 ctaactttca atactccccc ggcgtttact ctaatctttt ttcctaagat taatttagca
    13321 ttagattcct gttcgacagt tacattcttt ccaaatttta aaaaataatg aaaagtaaga
    13381 tccttgtttc gacacacttt taataatatc aagcaaatat ttgcacgaag taaaccaaca
    13441 atatttttta taatcctatt catctaaagc tccttttatt ttatctaaat aagcatctat
    13501 aataatttga cgagaaaaat attgctctat atacattctc ccttgaagtc ccatctcttt
    13561 tcgtttttca ttttctagac ctaaaaaaac ttccaatata gagactagtt cctcaacatt
    13621 tcccccttga aatatatagc ctgtctctct atctttaaca atttctttgc aacctggatt
    13681 atctgtcgta attaaaacac gtcctgaact agcgttttct agtaatacat tgctcattcc
    13741 ttcaccatac acactgggat ggataattgc atgggaacgg gtaatatgag gtatcacatc
    13801 tttttgttgt cccaaataat aaacgattcc ttttttttct aagtcacaaa ttttaagttc
    13861 ataattactc tctgtcggtt ctataaagcc aataatatta aactctgttt tgggatatcg
    13921 actcttaata atttgggcag cagccagata agtatctata cctttttctt ttaatatcct
    13981 accaataaaa ttaaaaacga ttgtttctcc ttgaattcca tttccaccat ttggatactg
    14041 ttgcacagga tacttttcaa tgttcactcc tgacccaggt atcagcttag agtcacccaa
    14101 aatcaagcca agagttttta acattttcat attatattca ttttgaaaaa aaacacaatt
    14161 tgatttccta aaagaaattc taaacagtaa taacaccagg cttcttacac aagaacccat
    14221 tgttaagaca ctacctaaac ctgttacgtt atttatatat tttattccta aaattgttgc
    14281 agctaggcta gcatatacat ttggtttcac ggtatatgtc aagactacat ccggtctata
    14341 ttttctcaat aatcttatat aactaagaaa tagacgaata tcttttaaag ggtttattcc
    14401 tcttctatca atagtaatat cttcatactc aaattgaata gacttcatca gctctatctt
    14461 atctccataa ggacatgaca ctagcacttc atacccatac tcaactagtg actctataac
    14521 ttcttttcga aaacaataga tatcatcgtc atgattagtt attaacataa tttttttctt
    14581 ttgtaaattc atcaaaataa tcttcctaaa atataattaa ccgctactcc attatccttt
    14641 acaactatca ttttaaaaat agtaattttc tataagtaat tgtttccaaa ttgtgacact
    14701 ttaaaattct atacacatat agaacttaca aactatttac gaccgtaaac tccatactta
    14761 tcaaccgaga tatccaattt atttaaaaca actcccagga acaggttccc tgtttgttct
    14821 aattgttgtt tcgctttttg gacatcacgt ttattcgcct cacctgttgc tgttatcaag
    14881 atggacgcat cacacttttg agtgataatt gccgcatcaa taacaattcc aataggtggt
    14941 gtatcaacaa tgatataatc aaaatattta cgcaatgttt caatcatatc attaaaattt
    15001 ttactttgta acaaggctgt agggtttggt gatacagatc ccgattgaac tacaaataaa
    15061 ttttcaatat ttgtatcaca taaaccgtga gataaatcag ctgtcccaga taaaaattct
    15121 gttagccctg taattttttc acgagattta aaaaatcctg acataactga atttcgaata
    15181 tcgccatcga acaaaagagt tttatagcct gcacgcgcaa atgacattgc tatatttacg
    15241 gaaatagttg tttttccttc ccccggatta acagaagtaa cggaaattac ttttagttta
    15301 tctccgctca actgtatatt tgtacacaag gtattgtaat attcttctgc cttcttaatg
    15361 aactccagtt ttttttgtgc tatttctaat gtcggcatct ctctctccta tttcaactta
    15421 cccaagtttg gtacaactcc caaaagtgtc atctgcagtg cattttcgat atcttccgga
    15481 cgtttcacac gagtgtccaa aagttcaaga agaagaacta taacactagt tccaatcacc
    15541 cctgccaaaa aaccaattag tgtattgcgt ttaatatttg gcgaagacgg tgatatcgcc
    15601 ggtcttgcct cctccagtgt tgtcacatca gaaacacgag taatactgat aattttttga
    15661 gcagctactt ctcttaaaga gttagcgata cggcttgcct cttcaggaac tcgatcacta
    15721 actgaaacag agacaatacg ggtatcaact ggtactgtta ctttaatttt attagccaaa
    15781 ccttttggca tcaaatctag tttcaaatca gaaataactt cctccaaaac atcctgcgat
    15841 aggacaattt cacgatagtc tttaaccaag tatgctcctg cctgcaagtc ttgattggtt
    15901 aaaccaggct tctctccctg attacggtta actacataaa tccgagtcgt actagtaaac
    15961 tcaggtttga taacaaaagt actgtaggca aaagcaactg aagaagttat aattgccact
    16021 aataaaatga ccaactttct tttccataaa gctctgaata gttgcaatac atcgatttcc
    16081 aaagtgtttt gttccttcat attttctcct aaattaattg atccattata atttttctgg
    16141 gattatctac aaaaagttct ttcgcttttt tcgctccata tttcttagca atgatatcat
    16201 atgcctgttg catatatgga ggtctactgt ctaaattgtg catgtcactt gcaactacat
    16261 gaactaaatc acgttccaaa aaataccgag ctctcttttt catgaattta tatttttcac
    16321 caaagaactt aggttttgaa acatgataac tatttatctg agtatagcac cccatatcaa
    16381 tcagttcacg aacacgtttt tcgttattct ctaaagcatc ataacgttca atatgagcaa
    16441 ttactggcgt gattcccaac atcaaaatat tgctcaatcc cgtatgaatc tgacgatagg
    16501 aagtatgcat gctaaactca atcaaggcat aacgactatc attaagggta ggaatttctt
    16561 ttttttctag cttttctaga gcatccagag tatagtatat ctctgcgcca taagcaatga
    16621 ctaaatcatc tgctacttct tttgcaattt cccgaacctg aagaaagttt tctgctatct
    16681 tctcttccgg agtttcaaac atgcccttgc gacggtgaga ggtagagaca atggttctca
    16741 ccccctgcct gtaggattct gccaagagag ccttgctttc ctctcttgac ttgggaccat
    16801 catctacatc aaagacgatg tgcgaatgga tgtctatcat tttatctacc ctccatcaca
    16861 tcctgtatag ctgctttaac tacagttaaa ctactatcat ctatttccat cacatagagg
    16921 ttactgtctg gcattgcata agaaggaaga tccatccgac ctgtcccttt taaatcttga
    16981 gaatttactt tataattccc tccactttcc aactgagtat tcactaaatc tatcatagtc
    17041 tcaatcggta tatttgtttg aagagaatcc tgcaatcctt gaagaatact actatagttt
    17101 ttcaaaacct ctgtagaagt taacttctga ataattgcta caatgacctt ttgttggttg
    17161 cgaccacggt cacggtctcc atcggttagt gagtagcgtt cacgtacaaa acctaaagct
    17221 tgctcagagt ctagatggac attccctact gggaaatgga acttcccatg tagagctgaa
    17281 aactcttgat cattatgaac atctacccct cccaataagt caatcatttt caagaaagaa
    17341 gtgaagttca atcgcacata gtaattgata tccactccat agagattttc taaggtgtga
    17401 atggacgaat caactccata aatgcccgca tgggttaatt tatctttttg attatttcca
    17461 ctatctgcga ttggtacata ggcatcacgt ggcgttgtgg tcaagaggat tttcttggta
    17521 tctcgattga cagtcattag gatattgaca tctgatcgcg acaccgaact aataggacca
    17581 taggtgtcaa ttccactaac atagatattg aaagactgat tcttagacgt cttaggagcc
    17641 tctacttttt tagtgaatcc cttggtataa atctttttta tcttcgatgc gtagtctgga
    17701 tactctgact cgatgatatt ttcaaagaca ctatttagga caatggcctt agtctcccct
    17761 gcaatcaaac tcttgtaagc tgccaagtaa gacgaactct ggttgaccgt caaatcggta
    17821 ttctgacttg acttgatatc agctagtagt ttttgaatat tttcattatc agtcccagtc
    17881 ggtgctgtca cactcgtcag ttgcgtaaca ttttcgatct tactatctgc taaaacagcg
    17941 acactgattg aatattctga gtaattagaa gtcgcattta aacgattggt cagtccaaca
    18001 aactgctgta ctgcaaagag cgacactgag ctgacaagga tagagaacag caacagaaaa
    18061 atagtaaact tttcagcttt tttatagata atcaagagta gccctaccaa ggcaactagt
    18121 aggactaacg cagttaccac taggttaaga tatctaaaag caaggatatt gtacttaaag
    18181 attaagaaca ataaaaaaca aattaacaat aaataaatag tcagcaaaac gatattaaca
    18241 cttcgcttca ctttctgtga acgtgatttt ttaaaacgtc tactcatgat taacacctat
    18301 accttgaaca tcatacaatt atatcacttt tttacggtaa tgtctacacc tttattttca
    18361 ctatctgcat ctttaagtat cttagtagac ttcccgcgaa ccaaaaatat agtaaaatga
    18421 aataagaata ggacaaatca atcaggacag tcaaatcgat ttctaacaat gttttagaat
    18481 cagatgtgta ctattctagt ttcaatataa
//
LOCUS       DAVBNZ010000040        18308 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000040 DAVBNZ010000000
VERSION     DAVBNZ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18308
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.040"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            166..480
                     /locus_tag="VQ860_001475"
                     /pseudo
     CDS             166..480
                     /locus_tag="VQ860_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            657..1316
                     /locus_tag="VQ860_001476"
     CDS             657..1316
                     /locus_tag="VQ860_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET3119888.1"
                     /translation="MKNLTKIKFKENGEFNHFSGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1341..2408
                     /locus_tag="VQ860_001477"
     CDS             1341..2408
                     /locus_tag="VQ860_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3119889.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            2511..3521
                     /locus_tag="VQ860_001478"
     CDS             2511..3521
                     /locus_tag="VQ860_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119890.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            3533..5224
                     /locus_tag="VQ860_001479"
     CDS             3533..5224
                     /locus_tag="VQ860_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3119891.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5227..5937
                     /locus_tag="VQ860_001480"
     CDS             5227..5937
                     /locus_tag="VQ860_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET3119892.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            6033..6224
                     /locus_tag="VQ860_001481"
     CDS             6033..6224
                     /locus_tag="VQ860_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119893.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKC"
     gene            6509..7510
                     /locus_tag="VQ860_001482"
     CDS             6509..7510
                     /locus_tag="VQ860_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3119894.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            8118..8192
                     /locus_tag="VQ860_001483"
                     /pseudo
     CDS             8118..8192
                     /locus_tag="VQ860_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            8651..10012
                     /gene="trpE"
                     /locus_tag="VQ860_001484"
     CDS             8651..10012
                     /gene="trpE"
                     /locus_tag="VQ860_001484"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET3119895.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            10009..10575
                     /locus_tag="VQ860_001485"
     CDS             10009..10575
                     /locus_tag="VQ860_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET3119896.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDDRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            10586..11590
                     /gene="trpD"
                     /locus_tag="VQ860_001486"
     CDS             10586..11590
                     /gene="trpD"
                     /locus_tag="VQ860_001486"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET3119897.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIARVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            11587..12354
                     /gene="trpC"
                     /locus_tag="VQ860_001487"
     CDS             11587..12354
                     /gene="trpC"
                     /locus_tag="VQ860_001487"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET3119898.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            12341..12940
                     /locus_tag="VQ860_001488"
     CDS             12341..12940
                     /locus_tag="VQ860_001488"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET3119899.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAV
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            12918..14141
                     /gene="trpB"
                     /locus_tag="VQ860_001489"
     CDS             12918..14141
                     /gene="trpB"
                     /locus_tag="VQ860_001489"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET3119900.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            14134..14910
                     /locus_tag="VQ860_001490"
     CDS             14134..14910
                     /locus_tag="VQ860_001490"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET3119901.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(14882..14983)
                     /locus_tag="VQ860_001491"
                     /pseudo
     CDS             complement(14882..14983)
                     /locus_tag="VQ860_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            15212..15352
                     /locus_tag="VQ860_001492"
     CDS             15212..15352
                     /locus_tag="VQ860_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119902.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WT"
     gene            15389..15943
                     /locus_tag="VQ860_001493"
     CDS             15389..15943
                     /locus_tag="VQ860_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119903.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            15958..17109
                     /locus_tag="VQ860_001494"
     CDS             15958..17109
                     /locus_tag="VQ860_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3119904.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(17161..17820)
                     /locus_tag="VQ860_001495"
     CDS             complement(17161..17820)
                     /locus_tag="VQ860_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET3119905.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            17890..>18308
                     /locus_tag="VQ860_001496"
     CDS             17890..>18308
                     /locus_tag="VQ860_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3119906.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGSRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVR"
BASE COUNT         5903 a         2959 c         3937 g         5509 t
ORIGIN      
        1 tactatatta tcgcttacca atatttgctt ttatatttgc taaactttca gaaaaaaagt
       61 tggagtatat gatgctaggt gactgcgtca tgttaataaa cgaaatggaa ataactgatc
      121 atagagtaga taacttattt gaaaaaggga aaaatgagat aaaagatcca tgtagtagat
      181 ttagcaatag gacatataaa agctttagaa aaagtatctg aaaaaacaga tgtttatatc
      241 tataacctag gctcgggaga aggcactagt gtattacaac ttgtaaatac atttgaaagt
      301 gttaataaga tccctattcc ttataaaata gttccaagac gttcaggaga cgttgcaatt
      361 tgttatgcaa atgcagacaa agcatataag gaattaaatt ggaggacaac aaaatcgatt
      421 gaagacatgt gtagagatac atggaattgg caatcaaaaa atcccaatga ctataattga
      481 tgatactgtc tatatgagtg ctgtattttg gaaaaattac ttaacctttt aatgaaatgc
      541 atatttaatg aaagataaat aaaaaaagtt tgacagcgct tgacaaagga aacggtttca
      601 ttgtataatg taaacatggt gacaccgatg tcaaatataa aaaagaaggt ctttatatga
      661 aaaacttaac aaaaattaag ttcaaagaga atggggaatt taatcatttc tctgggaata
      721 cagttgtagc aaatctttat actaaacaag atttgatgga agttgttgat attattcaat
      781 cacgttatag agaattacca tttatcgata agtttacttt aactccaagg aattctattc
      841 acatgactgt aattgaattg ttgtgccatg aaaatcgtga aacggagttt tggagcagta
      901 atcttcctct agatacacct ttacaggaaa tacatgatta ctttgctaaa caacttgaaa
      961 tttttccatt gttggatgaa gaaattcata tgcgtataac tgaaatggga aaacaaaaca
     1021 tactagttga acctgcagat gaagcttctg caaagagatt agaagaaatt cgtacttatg
     1081 tctcagaaaa agcaggtgtt tgtttcccta atcatgatag atatcaattc catatttcaa
     1141 ttgggtatct tcggattcct ctaaccgaag aggaggaaga agagtttact aaagtcagag
     1201 cagaattaac tgaaatttta ttagagaaga ttccaactat tactgtaaac cgtattgact
     1261 atactgtatt tgaagatatg agacaatttg ttccatatca cgaaaaattt aaataaaata
     1321 ataaaaaagg agaacttatc atgaaaaaaa tgaaagtttg gtctactgta cttgcaacgg
     1381 gagttgctct tactacactt gctgcttgct ctggaggttc aaattctacg actgcttctt
     1441 catctgaaga aaaagctgat aaaagtcaag aattagtaat ctattcgaac tcagtctcaa
     1501 atggtcgtgg tgattggtta actgctaaag caaaagaagc tggttttaat ataaaaatgg
     1561 ttgatatcgc tggcgctcaa ttagcagacc gtgttattgc tgagaagaat aatgcagttg
     1621 cagatatggt atttggaatt ggtgctgttg actcaaataa aattagagat caaaaattac
     1681 tagtacagta caagcctaaa tggttagata aaattgatca atctttatca gataaagata
     1741 attattataa tcctgtgatt gttcaaccat tagttttaat tggggcgcct gatgtaaaag
     1801 aaatgcctaa agattggact gaattaggta gtaagtataa aggtaaatat tcaatttatg
     1861 gtcttcaagg tggtacagga cgggcaattc tagcaagtat cttagttcgt taccttgatg
     1921 aaaaaggaga tttaggcgta tcagaaaaag gatgggaagt tgcaaaagaa tactttgcaa
     1981 atgcctatac tcttcaaaaa ggtgaaagct cagttgttaa agcgttagat aaagaaagcc
     2041 caattcaata cggtatgatc tggggttctg gagcgttaat cggacaaaaa gaacaaaatg
     2101 ttgaattcaa agttatgact cctgagattg gtgtaccatt tgtaactgaa caaactatgg
     2161 ttttaagcac tagtaaaaaa caagcgttag ctaaagaatt tattgattgg tttggtcaat
     2221 cagaaattca agtagaatat agtaaaaaat ttggctctat ccctgccaat aaagatgccc
     2281 taaaagagtt acctgaagat acgaaaaaat ttgttgatca agtgaaacca caaaatattg
     2341 actgggaagc tgttggaaag catttggatg aatgggtaga aaaagctgaa ttagaatacg
     2401 tacaataaga aataagagtt attttttatg tccaagtctc tctattattt ctaaatttat
     2461 ggaagaaata aagagaggct tttggtttag taatagaggg agttagtgag atgattaaat
     2521 ttgataatat tcaaattaaa tatggtgatt ttgttgcaat tgataatctg aatttagata
     2581 tacatgaagg ggaattcttt acatttcttg ggccttcagg atgtggtaaa tcaactactt
     2641 tgagagcatt ggtaggtttt ttagatccat catcaggaag tattgaagtt aatggaacag
     2701 atgtcactca tttggaacct gaaaagcgtg gaattggtat tgtatttcaa tcttatgcgc
     2761 tatttccaac tatgactgtt tttgataata ttgcatttgg tttaaaagtt aagaaggtag
     2821 ctccagatgt tattaaagct aaagtatcag cagtggcagc aaaaattaag atctctgatc
     2881 aacagttaca gcgtaatgta tcagaattat ctgggggtca acaacaaagg gtagcattgg
     2941 ctcgtgctct ggttcttgaa cctaaaattc tttgtctaga tgaaccattg tcaaaccttg
     3001 acgcaaaatt acgtgtagat ttgagaaaag agttgaaaag acttcaaaaa gagttaggta
     3061 ttactacttt atatgttact catgatcaag aggaagcctt gactttatct gatagaattg
     3121 cagtctttaa caatggatac atcgaacagg tcggtacacc agtagagatt tatcataatt
     3181 ctcaaactga atttgtatgt gattttattg gagatattaa tgttttgacc gatgaaacag
     3241 tccacgaagt attactgaaa aatacaagcg ttttcttaga agataaaaaa ggatacattc
     3301 gattagagaa agttcgattc aatcgtgaaa ctgaacaaga tttcattcta aaagggacaa
     3361 ttattgatgt tgagttttct ggagttacaa ttcactatac aataaaagtt tctgaaagtc
     3421 agattcttaa tgtaacaagt attgatagtc aggctgctat tagatctgtc ggagaaagtg
     3481 tggaattatt tatcacacca tcagacgttc tgcaatttta aggaggtgca gtatgcgtca
     3541 taaattaaat ttaaaagatt ggcttattcg tttagggtta atctggttct tagtaacatt
     3601 tattatttat ccaaactttg atctagtagt gaatgtattt gtaaaaggag gagaattttc
     3661 ccttgatgct gtacatcgtg ttctaaaatc tcagagggca cttcagagta ttatgaacag
     3721 ttttaagtta gcattttcac tcattattac agttaatgtc gtaggtattc tttgtgttct
     3781 atttacagag tactttgata ttaaaggtgc taaaatttta aaattaggtt atatgacctc
     3841 tttaatttat ggaggagtgg ttttagcgac tggatataaa tttgtctatg gtccttatgg
     3901 attgattaca aaatttttac aaaatgttat cccttcttta gactctaact ggtttattgg
     3961 gtatggtgca gtcttattca ttatgacatt ttcaggaact gctaatcata cattgttttt
     4021 aacaaataca attcgaagcg ttgactatca cactattgag gctgctcgaa atatgggagc
     4081 aaaaccattt actgttttcc gaaaagtagt gttaccaacc ttaattccaa ctctatttgc
     4141 acttactatt atggtttttc ttagtggttt atctgcagta gcagcaccca tgattgttgg
     4201 tggtaaagaa tttcaaacta taaatccaat gattattaca tttgcaggga tggggaattc
     4261 tcgtgattta gctgccttac ttgcaattat tttaggtatt gcaactacaa ttttgcttac
     4321 tatcatgaat aagatagaaa aaggtggaaa ttatatttct atctctaaga ctaaagcgcc
     4381 tcttaaaaaa caaaaaattg cgtctaagcc ttggaatatc attgctcaca ttgtagcata
     4441 tggattgttc acagttttca tgcttccact aatttttata gtattatact catttacaga
     4501 tccagttgca attcaaacag gtaacttaac attatcaaac tttactttag aaaattatcg
     4561 cttattcttt agtaatagtg cggcattctc tccattcttg gtcagcttta tttattctat
     4621 tattgctgcg acaacagcaa caattctcgc agttgtattt gctcgtgttg tcagaaaaca
     4681 taaatctcgt tttgatttct tatttgaata tggtgctcta cttccttggt tactaccaag
     4741 tacactttta gcagtaagtt tattatttac ttttaatcag ccacaatttc ttgtcttgaa
     4801 tcagattttg gtaggtagtt tggtaattct acttattgca tatatagttg taaaaatccc
     4861 attttcttat agaatggtac gtgctatttt atttagtgtt gatgatgaga tggaagatgc
     4921 agcaagaagt atgggtgctt caccttttta tactatgatg aaggttatca ttccatttat
     4981 tttaccggtt gttctctctg ttattgcttt aaactttaac tctttattaa ctgacttcga
     5041 cttatctgta ttcctttacc atcccctagc tcaaccatta ggtattacga ttcgatctgc
     5101 aggtgatgaa acagcaacat ctaatgcaca agctctggta tttgtttata caattgttct
     5161 gatgattatt tctggaacgg tattatactt cacacaaaga ccggggcgta aagtaaggaa
     5221 ataatcatga cagccactag tcttgggtta tcaaatattg aaatagttgt caggattgtt
     5281 ttatcagtag tcattggtag tataattggt ttagagagag ggagcaaatc ccagcctgca
     5341 ggcatccgaa cttatagtat tgtttgtcta gctgcatgtt tgattatgat gacgaatgaa
     5401 tacgtatctt ataaatttgg gacaggagat cctacacgat taggagctca agttatatca
     5461 ggtgtgggtt ttctaggcgc tggaacgatt cttattacag ataaaaagaa aattacaggt
     5521 ctgacaactg cagcaggcat ttgggcttcg gcaggaattg gattagctat tggagtaggt
     5581 ttttatgagg gagctctttt agtagctatt tctgtttggg gtgtgatatc catgttccaa
     5641 ccactaaaaa aatatctgca aaatcgttct aaaatgattg aattgtatat agtggttaaa
     5701 tctacagaag cctataatcg tgtattggtt tattgtgcag aaaatggtat cagaatgacc
     5761 gattcaagaa cagcgtttgg agatgttaat tctgacagaa ttgaatactt tgatgttcca
     5821 gataaaaaaa tagcgtcatt tattactctg gaattatcag gtagatttga acatcttcga
     5881 ctgatggaag aaattgctaa tattgtaggt gttatttatg tcgaagaaat tagctgaaat
     5941 ttagtaaaca aagggacaga tgtttttgtc cttttgtttt ttagatgttt taatcatcta
     6001 atttttgagt agatttttgc tcagaggttt ttatgaaaga ttataaaatc aattttgatt
     6061 taggtaaaat agaatatttt gataataatt gtttgataca agtatacaaa tttatttctt
     6121 tttatgatat ttgtgaaatg gtgtttgcct ttcatttacc tcctgatgag ttgataacaa
     6181 atgttatctt taaagaaaaa attaactcta tgttaaaatg ttaaattgac aggctattat
     6241 atgtttttat aaatcctaca cattttactg aaaaagttaa tctacaattt tatggtagtt
     6301 ttttctcata tgaatttatt tgtcgtgaag ttggaaacat tcttaaaaat aaaggtgtga
     6361 aatgcaattt aaactttttt gaagggaaag aatatttgta aaattaattt tgtgaatttg
     6421 tggatcttaa ataatttact aaattctctt gttaaaaaaa attaaatatt gtatagtaat
     6481 attagaatgt tcgtaatgga ggactgaaat gaaaaatata aatgggaaaa aggtaactat
     6541 ttatgatatt gcacgtttat caggtttttc tccaaaaaca gtttcacgag ttattaatgg
     6601 tggagtaaat gttaaagaag aaacttatca agcgattcaa aaagttatag aggaattgtc
     6661 gtatattcca aatgcgtatg caaaaaattt aactaaaaaa gaagctataa atatattgat
     6721 ttctgtaaaa aaaatcgact cttttccttt aatttggttt catacgctgt tagataaagt
     6781 gttacggacg tgtaaagaat ttggtgttaa tgctatagtt gagtactttg gagaggagga
     6841 tacaattagt aattcaatta tatcaagcac aggtagccta gtagatggtg ttattgtttt
     6901 ttatgaaagt gtagatgata tcagaattca gtatttaaag aagaaccata tgccttttct
     6961 tgttttcggt gaatctcaaa cgtctggagt agtctatgta tctaataata attttcaagc
     7021 tacttatgat atgatgaaag ctgtaactga agaaaaattt aaaaatatgt ggttgcttat
     7081 gggaggagaa tcccatgtta ataaggatcg tgaaagaggt gtgcgttctt ttctgaatga
     7141 taaaaattac tttatggatt taaaagtcat ttatggctta tctacaattg attcagttta
     7201 ttcttatgca atgcagcact tgactaccca aaattatccg gacattattt ttgtttcagg
     7261 agatgaaaag gttcaaggct tgattcgtgc gtgctatgag aaaggaattc ttattccaga
     7321 tgatatttct atcattggat ttgataatat tcctatttct cagtattata ctccagcttt
     7381 gtctacaatt gctcccaatt atgttaaatt ggctaaagaa atgatagaag gtgttttagc
     7441 aattattaaa ggggaaagtg tcacatctgt tgaagtttct cctaaatttg ttaggagaca
     7501 gagtttctag tattgtttaa ttcttgaaaa tcctagtgga aaagatggag tgttctaaaa
     7561 taagttctgt ttagcctcca ttcagtttct attgagttgg atccaatttc taacgagtgg
     7621 gacatgttca tgttcgatct aaggaagaca tggtcacatt cgaatgatat tttcaaaaaa
     7681 atcgtaaaaa agtcttgaca aagaaaaaac aaagtattaa aataagttca acaaatcaga
     7741 aaagtaacta tttttgatct tcagggagcc tgtggtgatt gtgaataggt ggttggaagt
     7801 agtgaaagtg ggctgatttt gaaaatgaat ttgaaacaat gaaaattcgg tgcgcacacc
     7861 ttacagtgca gcttgttgtt aaacaaggca gagatgtaaa gggatagtcc ctttataatt
     7921 gaggtggcac cgcgttacca acgccctcac acggaagtat attctgtgtg tgggcttttt
     7981 tctatccgtc gtttgcttta tcttttatta gggccttaac tcgctttgat gaacttgagt
     8041 tctatctaca gctccttgcc tcctactaaa agtaaacaaa aaggctggac taatacgaaa
     8101 aaagctagta atactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggttgct
     8161 caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagtaaccat acctacgata
     8221 aggcgacgtt gacgcggttt gaagagattt tcgaagagta taaaggtgta ccgagatgaa
     8281 catctcttca tcaatgtctc tggtcgtgga ggcaaggacc tagctgcgat tgcagattac
     8341 tagaagctaa aaaataatag atggaaaaat tacagtcttt tctctcacag agagcttgtg
     8401 gttgctgaaa acaagcagag aaagctgtaa agttgggttc atctgaaacg agagaagaaa
     8461 acatcattct caagggagtg ccctttatcg cacagcctgt tacaggaggt atctgagaca
     8521 ggaatgagag ataggagaaa tcctataatt gaggtggcac cgcgaatttc gtcctcacgc
     8581 aagttatttt gcgtggggat ttttcataca gtcgccacga actagaatta gaactgaaag
     8641 ggaaattaca atggaacgaa tcattcatgg agatgtctta tcaccaatct tggcttatat
     8701 gcgcttaaag gggcaacata aggttatttt agagagtatt ccgagagaca aggaaacggc
     8761 tcgtttttct atcctagcct ataatccagt ttttgagatt aagtttgaaa atggagttct
     8821 ctatcaaaat ggtcaagtga ttgatcggga tcccttggat ttcctttatg aagtgattca
     8881 taagagtcag caccattcag agctcccttt tggtggtgga gccattggtt ttgtgggtta
     8941 cgatatgatt tcgctttatg aagaaattgg tcaaatccct gaggatacaa ttgggacgcc
     9001 agacatgcat ttctttgtct atgagagcta tatggtcttt gaccacaaga aggagaagat
     9061 acatgtcata gaggatgcac tttatagtga gcgcagtcaa gaggccttgg aaaaatcctt
     9121 gaaccaagtg cttgaggaat tacgcattcc tgctccaaat gaatttgaag acttggattt
     9181 atcaccactt gacttcaaac cgcatatcgc tccacataag tttgagggaa tggtagaaac
     9241 agctcgtgac ttgattcgta acggtgatat gttccaatgc gtactcagcc agcgcttctc
     9301 agcagaggtt actggaaatc catttgactt ctacagaaat ctccgcgtga ctaatccttc
     9361 taattacctt tatttctatg attttgggga ttatcaaatc atcggagcca gtccagaaag
     9421 tttggtttct gtcaaaaatg gcatcgtgac aaccaatccg attgcaggga cgcgaccaag
     9481 aggggctacg gatgaagaag acaaggcctt ggcgactgac ctcctctctg atgagaagga
     9541 aacagcagag catcgaatgt tagtagacct gggtcgtaat gatattggtc gcatctctga
     9601 aacgaccagt gtccaagtca ctaagtatat ggaagtggag ctcttccgtt atgttatgca
     9661 tctgaccagc gtggtcaagg ggcgtttgct tccagaactc actgccatgg atgccttgaa
     9721 agctacactt cctgctggaa ccgtttctgg agcaccaaag attcgtgcta tgagacgtat
     9781 ctatgaactg gaaacagaaa aacggggcgt atacgcagga gcaatcggct acttgtctgc
     9841 gacgggtgat atggatttgg ccattgccat ccgaaccatg attctcaaaa atcaaagagc
     9901 ctatgtgcag gctggggcag ggattgtcta cgactctatc gcccaaaacg aataccaaga
     9961 aaccattaac aaagcaaaat ctatgactag aattggagaa ctaagaccat gattttattg
    10021 attgacaact atgattcttt tacctataac ttggcccaat acattgggaa ttttgcagaa
    10081 gttcaggttc tgagaaatga tgattccaag ctgtatgaag aagctgaaaa agcagatggt
    10141 ctggtctttt ctcctggtcc tggttggcca gttgatgctg gaaagatgga agacatgatt
    10201 cgtgactttg caggcaagaa gccgattcta gggatttgtt taggccacca agccattgca
    10261 gaagtctttg gtggtaagct aggtttggct ccaaaagtca tgcatgggaa acagagcaat
    10321 atcaactttg aagcgccatc tgttttgtat caaggtattg aggatgaccg tgcggtcatg
    10381 cgttatcaca gtattttgat tgaggaaatg ccagaagact ttgaagtgac agctcgttcg
    10441 actgatgacc aagccatcat ggggattcaa cataaaaacc taccgattta tggcttccag
    10501 taccatccag agagcattgg aacgccagac ggcttgtctt ctattcggaa ttttatcgag
    10561 aaggttgtaa agtgaggaaa ctaggatgaa agagattatt gaaaaactag caaaatttga
    10621 aaatttatca ggtgtggaaa tgacggatgt cattgagcgt atcgtaactg ggcgtgtaac
    10681 tgaagcgcag attgcttctc tcctcttagc tcttaagatg aagggggaaa cacctgaaga
    10741 acgcacagcc attgcccgag tcatgagagg acatgcccag catattccaa ctgagattca
    10801 tgatgctatg gacaactgtg gtacaggtgg ggacaagtct ttcagtttta atatttccac
    10861 aactgcagcc tttgtcttgg ctggtggcgg tattcacatg gccaagcatg gtaaccgctc
    10921 gatttcttct aaatctggtt ccgcagatgt cctcgaagcc ttgggaatca atcttgacct
    10981 caaaccagct gaactaggta aggtctttga taaaactggc atcgtctttc tcttcgctaa
    11041 aaatatgcac ccagctatga aatacatcat gccagctcgt ttggaattgg gaattccaac
    11101 gattatgaac ttgactggtc cactgattca tccaatggct ttagaaacac agcttcttgg
    11161 aattagtcgt ccagaactcc tagaaagtac agctcaggtt ttgaaaaata tgggtcgcaa
    11221 acgtgccatc gtggttgctg gaccagaagg gttggatgaa gctggcttga acggaacaac
    11281 caagattgca cttcttgaaa atggcgaaat cagcttgtca agctttactc cagaggattt
    11341 gggaatggaa ggctatgcta tggaagatat tcgtggtggg aatgctcagg aaaatgcaga
    11401 aattttgctt agcgttctga aaaacgaagc aagtccattc ttggaaacga cagtcttgaa
    11461 tgctggtctt ggtttctatg ctaatggtaa gattgatagc atcaaggaag gagttgcctt
    11521 ggcccgtcaa gtgattgcta gaggcaaggc ccttgaaaaa ctcagactgt tacaggagta
    11581 ccaaaaatga gtcaggaatt tttagcacga atcttggagc agaaggcgcg tgaggtggag
    11641 cagatgaagc tggagcaaat ccagcctctg cgccagacct atcgcttggc agaatttttg
    11701 aagaatcatc aggaccgctt gcaggtaatc gctgaggtca agaaagctag ccctagtttg
    11761 ggagatatca atctcgatgt ggatattgtg caacaggccc agacttatga agaaaacgga
    11821 gcagtgatga tttcggtgtt gacagatgag gttttcttta aagggcattt ggattatcta
    11881 cgggaaattt ccagtcaggt agagattccg acgctcaaca aagactttat catagatgaa
    11941 aagcaaatca tccgcgctcg caatgcaggt gcgacagtta tcttgcttat tgtggcagcc
    12001 ttgtccgaag aacgcctcaa ggaactgtat gactacgcga cagagcttgg tctggaagtc
    12061 ttagtggaga ctcacaatct agctgaacta gaggtagccc acagacttgg tgctgagatt
    12121 atcggggtca acaaccgcaa cttgactacc tttgaggtcg acttgcagac cagtgtagat
    12181 ttagcccctt actttgagga aggtcgctat tacatttctg aatctgccat tttcacaggg
    12241 caggatgcgg aacgactagc cccatacttt aacggaattt tggtagggac agctcttatg
    12301 caggcagaaa atgtggccca gagaatcaag gagttgcaga ttgacaaagg ttaaaatttg
    12361 tggactatcg accaaagaag cggtggaaac agccgtttca gcaggagccg actatatcgg
    12421 ttttgtcttt gcacctagta aaagacaggt gactttagaa gaggcagctg tgttggcaaa
    12481 gcttattcct gcagatgtga aaaaggttgg agtatttgtt tcaccaagtc gggtagaact
    12541 gctggaagcg attgacaaag ttggcttgga cttggttcaa gttcacggtc aggtggcaga
    12601 tgatttattt gagaatttgc cttgtgccag tattcaggct gtgcaggtag atggaaatgg
    12661 gcatgtcccc aattctcagg cagattatct actctttgat gcccctgtgg caggaagtgg
    12721 ccagcccttt gattggggtc aactggatac gactggacta gcacagccct tctttatcgc
    12781 aggtggcctt aatgaagata atgtagtaaa agcaattcaa cattttactc cctatgcagt
    12841 agatgtatcg agcggagtgg agacagatgg acaaaaagat catgaaaaga ttagaagatt
    12901 tatagagagg gtaaagcatg gcatatcagg aaccaaataa agatggattt tacggaaaat
    12961 tcggcggacg ttttgtccca gaaacattga tgacagcagt tttggagttg gagaaggcct
    13021 accgtgaaag tcaggcagac ccaagtttcc aagaggaatt aaaccagctt ttgcgccagt
    13081 acgtaggacg tgaaactcct ctttattacg caaaaaactt gacccagcat atcggcggag
    13141 ccaagattta tctcaaacgg gaagacctta accatacagg agcccacaag attaacaatg
    13201 ccttaggaca agtttggctt gccaaacgca tgggtaaaaa gaaaattatc gcagaaacgg
    13261 gtgctggtca gcacggtgtg gcaactgcaa ctgctgcggc cctctttaac atggaatgta
    13321 ccatctacat gggtgaggaa gatgtcaaac gccaagccct caatgtcttc cgtatggagc
    13381 ttttgggagc taaggtcgag gccgtgacag atggttcgcg cgtgctcaag gatgcggtca
    13441 atgcagccct tcgttcatgg gtagctaata tcgatgatac ccactatatc cttggttctg
    13501 ccttggggcc tcatccattt ccagaaatcg ttcgtgactt ccaaagtgtc atcggtcgag
    13561 aggctaaaca acagtaccgc gatatgacag gtcaagatct gccagatgcc ctagtagcct
    13621 gtgttggtgg tgggtcgaat gctatcgggc tcttccatcc ctttgtagaa gatgagtcag
    13681 tagctatgta tggaactgaa gcagcagggc ttggtgtgga tacagagcac cacgctgcta
    13741 ccttgaccaa gggtcgtccg ggtgttcttc acggttctct catggatgtg ctccaagatg
    13801 cccatggtca aattcttgaa gccttctcta tctcagcagg tttggactat cctggtattg
    13861 gtccagaaca ttctcactac cacgatatca aacgtgccag ctatgtccct gtgacagatg
    13921 aagaagcctt ggaaggattc caactcttgt ctcgtgtgga agggattatc ccagccttgg
    13981 aatctagcca tgctatcgct tttgcggtga aattggccaa agaacttgga ccagaaaagt
    14041 ctatgattgt ctgcctatca ggtcgtgggg acaaggatgt ggttcaagtc aaagaccgct
    14101 tggaagcaga tgcagcaaag aagggagaag ctcatgccta agacactaac agaaaaattg
    14161 aatgctatta aagcagctgg aaaaggaatt tttgttccct atatcatggc tggtgaccac
    14221 gagaaaggtt tggacggtct tgctgaaaca attcactttt tagaagattt gggtgtctct
    14281 gcaattgaag tgggtattcc cttttcagac cctgttgcag atggacctgt tatcgaagaa
    14341 gctggcttgc gcagtttagc ccacgggacc tctacccagg ctttagttga aaccttgaaa
    14401 accattgaaa cagagattcc actggtcatc atgacctact tcaaccccct ctttcagtac
    14461 ggtgtggaga actttgtcaa agatctggct gatacagctg tgaagggctt gattatccca
    14521 gacttgcctc atgaacatgc caactttgta gaaccatttt tggcagatac agatatcgcc
    14581 ttgattcctt tagtaagctt gaccacagga attgagcgcc agaaagagtt gattgaaggc
    14641 gcggagggat tcgtctatgc cgttgccatc aatggggtga cagggaaatc aggcaattac
    14701 cgtgcagatt tggacaagca cttggcgcaa cttcatcaag tggccgacat cccagtcttg
    14761 acaggttttg gtgtatctag tcaagccgat ctggaacgct tcaatgcggt gtcagatggt
    14821 gttatcgtcg gttcgaaaat agtaaaagct ctccaccaag gagagccgat tcaggatttt
    14881 atcagacaag cagtagctta ccaaaaataa tcaaacaagt agcaagtaag aggaaaggca
    14941 cgaaaggaag tctttccttt ttcttttgca ggcgaaaggc tagttttata gtgaattgaa
    15001 tctggaatat tacactacgg ttcctaaaat attttaagaa agtgatttga atttcccaat
    15061 aaatttgttc agtttttaat tgattttact atagaagata taattttcta aattactctg
    15121 acacagaact ttaagaaaaa gctaattatt gtagtaattt ctttaagaaa atgatataat
    15181 tcattaaaaa gtatttggag gaggaagaat tatgttgaat caggatctct ttgattcgct
    15241 tgaggcacaa aaaattgtag atactttgat gaaagggcaa aaagattatg tagatgaacg
    15301 tctagaaaaa agagagacaa tgatagtgtc gaatggttat gcatggacgt gacctaatca
    15361 tattgatact gcatttgcat cagcagattt gtttgagtat aaattacaat tagcaggaca
    15421 gacttgggga tatttagaat ttgaaacaaa tacagaaaaa tatgggaaag tattgttaat
    15481 tataaagggt aagaagcgac ttacgaacca atttcctttg gtacaaaaaa ataagagtgg
    15541 ctacttattt gaatatgctc agatgaatac actttatctt aatcaacatt cttcctacaa
    15601 aaatgatgaa gatagtcatt cctttccaat tcagatggag ttagtttctg atgaaatgat
    15661 tcaagaaatt gaacaagcta ctaaaaattc gaatatcgaa aaatttatga ttttaactta
    15721 tgaggcggac tcagaaaaca atattatatc tgtagatgtt gttatgcctg atgcacgaac
    15781 tggtcagtta cacttgattc aagatttgtc tgagtatatt caatcaagtt cgtaccattt
    15841 cgaagaagct aaatatcaag atattcctaa tttttcagaa ttatcggaaa cagaagattt
    15901 tgaaattatt ccaagaatag aaaaacaaga aggtcaaaag tagtaaggag tatgtaaatg
    15961 tttaatggtc gggtattgaa agaattacgg ctgttaaatg gtttaagtag agcagaatta
    16021 gctcagagaa ttaatttaac ggaacaagcc atttggcagt ttgagtccaa cgaaacgaaa
    16081 cctaaattat caaccaaaat gcatttggcc aaccaatttc atgttgattt aacttatttt
    16141 gaacaggaag aagagagcat tcgatttgat tcttctgtaa ttgcctttag aaatgcagac
    16201 ctagcaacac ggaaaacaat agatattcaa actatgtatt tacataaggt agatagtttg
    16261 attgattatt ttgaaagttt tgtaattata cctaatatta taattcatga cctaagtaat
    16321 gtagtgagtg aatcttatca taagggagaa tccattgagg aattggctct ttatgccagg
    16381 gaaaaattag gtatttcaaa agataatcat gatttgcttt ataaattaga acgttcaggc
    16441 atctatatcg tggaacgatt aattaatggc caagctgatg cttatagcgc atggtcaaaa
    16501 ttgggaagac cttatattgt gttgggaacg aataaatcat ctgtacgtcg aaattttgac
    16561 ttagctcatg agctaggaca tattctttta cataaatata aagatatgaa tgaagatggc
    16621 gatcgtttgg agcaagaagc aaattatttt gcatcatgtt ttttattgcc aaaagaagag
    16681 tttttagtca aatttgaaga gagggttggc aagcgtgtca gcaatcctga tagttatatt
    16741 ttattgaagt cggatttgaa tgtttcgata caggctttag agtatcgagc ttttaagtta
    16801 ggattattga ctccaaagca acattcttac ttttatcgtc aaattgcgca aaaaggttac
    16861 aaaatgattg aacctttgga tgatcaaatt tttgttaaaa aaccaagcaa agtaaagagt
    16921 attctggacg tcgttttgag taatcatcta gtcagtctag cgactataat gtctaaacaa
    16981 agtattcgtt tacagtttat aagcgaaata ttttcagtcg aaatgaaatt ttttgatcag
    17041 tatcaagaag atagaagaac agatcgattt gataacatca tccctttgta caaaagaaat
    17101 aatttataat ttaactgtga aataatttca tgaaggacat atggcagaaa ttggacttta
    17161 tcaaacaagc agtagcttac caaaaataat caaacaagta gcaagtaaga ggaaaggcac
    17221 gaaaggaagt ctttcctttt tcttttgcag gagaaaggct aggatacccg tcgcagaagc
    17281 aaactgaatc aagatcagta actccgttat gctaaagacg agagcacaag aagctaaaaa
    17341 gaggaaatcc cctgcgccca tgcggatatc gataaaatga gccaaaattc caagagcaag
    17401 gaaggagacc atgaccagat tccagccaga ggaagctatt aggattaggt ggaaagtcat
    17461 ccagaccagt aagggatatt cctgatggcg aaagtcatag atgctcaagg tcaaaccagc
    17521 ggtgattagg acgacttgcc ccaaggaaag caattcccaa gagtaaagca gaaagaggag
    17581 tcctaagcct agttcaaaga gggcatacca gacaggatag cggaccttgc agtagcgaca
    17641 gcgaaagcga ttgaagacct gtgagagaat cggaatcaaa tctaagggac gcaagggagt
    17701 ctgacaggaa tcgcagtgac tggctgaact gataatggat tgctctggaa aacggtcaat
    17761 gaccaaacca agaaaggaag cgagaatgct cccgacgaga aaaaaataaa aatcaatcat
    17821 acttatctat tcgtaaaaaa tgggagaaat agtataatgg agaaacatag ataagatggt
    17881 gaggaaaaga tgacaattcg ttttgaagaa aaggtgagta tagaaaacgc tcaatttgta
    17941 tgccaatggt ccaactccct aggcaaatcc tttcaagaac aatggatggg atcaaggatt
    18001 ccttttctac tgacccttca agccttggaa gaagtctttt caatctttga tgaacaagag
    18061 tttgtgggac ttatccagaa aatcaggcta gaagacagca atcttcatat cgggagattt
    18121 tttatcaacc cccagaaaca ggggcaaggc ttaggtagcc aggctttaag gaaatttgtt
    18181 agtttggcct ttgaaaatga agatatagat agtatttctc taaatgtctt cgaggcaaat
    18241 caaagagctc agaatcttta ccaaaaagaa ggatttgaaa tcgttcaaat ggttgaagca
    18301 cctgtacg
//
LOCUS       DAVBNZ010000041        18177 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000041 DAVBNZ010000000
VERSION     DAVBNZ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.041"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ860_001497"
     CDS             complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ860_001497"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET3119907.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(863..2125)
                     /locus_tag="VQ860_001498"
     CDS             complement(863..2125)
                     /locus_tag="VQ860_001498"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET3119908.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVS
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(2135..3265)
                     /locus_tag="VQ860_001499"
     CDS             complement(2135..3265)
                     /locus_tag="VQ860_001499"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET3119909.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ860_001500"
                     /gene_synonym="pce"
     CDS             complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ860_001500"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET3119910.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(5231..6118)
                     /locus_tag="VQ860_001501"
     CDS             complement(5231..6118)
                     /locus_tag="VQ860_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3119911.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVIAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIDHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(6108..6569)
                     /locus_tag="VQ860_001502"
     CDS             complement(6108..6569)
                     /locus_tag="VQ860_001502"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET3119912.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRASQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(6566..7474)
                     /locus_tag="VQ860_001503"
     CDS             complement(6566..7474)
                     /locus_tag="VQ860_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3119913.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            7467..7664
                     /locus_tag="VQ860_001504"
     CDS             7467..7664
                     /locus_tag="VQ860_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3119914.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(7716..8387)
                     /locus_tag="VQ860_001505"
     CDS             complement(7716..8387)
                     /locus_tag="VQ860_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3119915.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(8441..8662)
                     /locus_tag="VQ860_001506"
     CDS             complement(8441..8662)
                     /locus_tag="VQ860_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET3119916.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            8934..9743
                     /locus_tag="VQ860_001507"
     CDS             8934..9743
                     /locus_tag="VQ860_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3119917.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKLRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ860_001508"
     CDS             complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ860_001508"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET3119918.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ860_001509"
     CDS             complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ860_001509"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET3119919.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALGRPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ860_001510"
     CDS             complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ860_001510"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET3119920.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGVDDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPSLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(13018..14277)
                     /locus_tag="VQ860_001511"
     CDS             complement(13018..14277)
                     /locus_tag="VQ860_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET3119921.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ860_001512"
     CDS             complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ860_001512"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET3119922.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            15390..16105
                     /locus_tag="VQ860_001513"
                     /pseudo
     CDS             15390..16105
                     /locus_tag="VQ860_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(16071..17546)
                     /locus_tag="VQ860_001514"
     CDS             complement(16071..17546)
                     /locus_tag="VQ860_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET3119923.1"
                     /translation="MKEVDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT         5331 a         4168 c         3325 g         5353 t
ORIGIN      
        1 agtttgaatt tgattttcga agagtatcaa ccaccataaa agaggcagat aaaactacct
       61 cttatttacc tagttcttgt gttcgtttat aggcttgatg aactgcatcc atgaccgttc
      121 ctcgaaaagc atgcgcttct aggcttgcta cgccagcaat agtcgaaccg cctggactac
      181 aaacttgatc tttcaaaact ccaggatgtt gctggctttc taggaccaat tgcccagctc
      241 ctaccacagt ttgggctgcc attttcaagg ctgtttctcg tggtaatccc gtctgaacac
      301 ctgcatctgc caaggcctca ataaagagat agacaaaggc tggtccacaa cctgcaagac
      361 ctgtcgctgc attgattaag ctttctccta attcaaccaa gagaccagcc ttggctaaaa
      421 gctgacaaaa gagctcactg tcctcagccc tgcaattagg agacaaggca taactaatca
      481 ctccttgccc gatagaagca ggggtattag gcatcatacg aataattcgg tgttggcttg
      541 ggataagact tgctagtttt tctaaggtca atccagctgc catcgaaatc aaaagaagac
      601 tttctctttt ttcaaggatg gtctggtatt gagaaagcag ttcagaaaac tgagcaggct
      661 taacacctag aaaaatcaca tctgcttctt cgaatatttc ttcattgtta gaagtctgac
      721 caccgaagtt agcgatgaaa gcatccacct tgacttgact acgattggca aggagaatct
      781 catctgacgg tctagcctgc aagacagact tggctaaact agcacccata ttccccaaac
      841 cgataaatcc aatcttcatc ccttactccc ttatctgtcc atcaccagtg accacatact
      901 tgtagctagt caattccttc aagcccatgg gaccacgcgc gtgcaatttc tgagtagaaa
      961 tccccatttc acaaccaaga ccaaattgtc ctccatctgt gaaacgagtt gaggcattaa
     1021 catacaccgc tgcagagtcc acttgatctg taaagtatgc tgcagcttca gcattttccg
     1081 tcacaatagc atccgaatga tgagtgctgt gggattcaat gtgcgaaacc gcttcttcta
     1141 aactgctcac aaccttaaca gcaaggacat agtctaaaaa ctcggtgtca aagtcttggg
     1201 tctcagctgc ttgacctgaa acaaactggc ttgctttgct atccaagcgg aattgaattg
     1261 gttccagtcc agcttcctta cgctctgcaa ccagcatttg atccaagcga ggaaggatgc
     1321 ttgctgcctt gttttcatga accagcagaa cctccatggc attacaaaca gaaggacgac
     1381 tggttttagc attgttgatg atagacagcg ccttgtcttc gtctgcatcc ttatccacat
     1441 agacatggac aatcccagtc cctgtctcga taacaggtac aatcgcattc tcaaccactg
     1501 cattgatcaa gccagctcct ccacgaggaa tgagaaggtc tagatagccc ttggccttca
     1561 tcatagcata actactttca cggctagtat cctccaccag ttgaatcaca tttggatgaa
     1621 tagtagtcgt ctccaagccc ttcttcaagg ctgtgacaat ggcatgggtt gtttgatagg
     1681 catccttacc actacgaaga acaaccgcat ttccactctt aagagtcaaa gcagccgcat
     1741 cagacgtcac atttggacgg ctttcataga taataccgat gacacccata gctacacgtt
     1801 tttttgtgat aaccaaacca ttttcaagct gacttgtttc taaaacttca ccgattggat
     1861 ctggtaaggc aaccacttca cgaattcctc ttgccatcgc ttctatacga tctgcatcca
     1921 aataaagacg atccaacatc acatctgaga ttttcccctt agccgctgcc atatcgaggg
     1981 cattagccgc taaaatttcc tcagtagcag ccactaagtg atcagccatg gctagcaagg
     2041 cttggttttt cacttcttca ctagctgtgt taatcgattt tttaacagcc tgtacctgtt
     2101 caaattgttc ttgtctactc accatagttt acctctaaaa ttctgtaaaa agtagttgga
     2161 tttcaggagt aatggaaatc cagtcgtcac ggtaaatcaa gacacccttg gctttttgag
     2221 aacgcaacat atcctccaaa gcagatgctc caaattgcac gcgtcctttt ccaagtgatt
     2281 ttccactttc cttgtcaaat actgtcacga tatcaccgta agaaaaggct ccttctgctt
     2341 caacgatacc agataagaga agactctttc catgttgaga gagagcttcc gcagcccctt
     2401 tatcaaccca aatagaacct tgactctgag catagaaggc aagccattgt ttctgggtac
     2461 gaagcccctt ctcttgagca acaaagtaag aaccatcctc ggtctcctct gccgcctcaa
     2521 tcatggaatc tgatttcaag gatgagcaaa tataaacagg aactcctgat tccgtcgcga
     2581 tagttgcagc cttgattttg gttaacatac ccccagttcc gtttgacgaa cctgctccac
     2641 cagccatatc aataatctca cgattgatgg tctcgattct ctccaagcgt ttggctcttg
     2701 gatctgaatt aggatttcca gtatagagac cgtccacatc tgtcaagaaa actaaaaggt
     2761 ctgcttggac catcgccgct acttgagcac ttagagtgtc attgtcccca accttgagct
     2821 catcaataac gacactatca ttctcattga tgataggaat tgccccacgg ttgagcaaaa
     2881 ccgacaaagc ctgatgggca tttttataac gacgcttatc cacaaagtca tcttgggtca
     2941 gcaagatttg tgcagaaacg atttgacgca agagaagatt ggtcgtatat tcttccaaca
     3001 aaagtccctg ccctaccgct gctgaagcct gtttatcagc aattttagtc ggacgctttt
     3061 taaatcctaa ggctccaaaa ccagccgcaa tggcacctga agacaccaaa atcaactcat
     3121 gaccagcctc gtgcagcata gccaactgct gggtaatatc ctttacctta ctacgtgata
     3181 aacttccatc ctcatttgtc agagaagaag tacccacctt aaagacaatc cgtttgtatt
     3241 tcatagtctc actccgatta ttcatattta tccattataa catgaataac aggaaataga
     3301 aaagagttga taggaaaaag aaggccctaa aaccttcttt tctactactg ttctgattcc
     3361 gatttgttta cactcgtttc agagctttgt gaagttgagg atgtcaaatc ttgactagtt
     3421 gaagaatttg taacactttc atgttgactc gtttctttat tttcaagatc ctttttcact
     3481 acttctttgg attcttttat ttctgaatga cttgtagttt taattgtagc agatttctcg
     3541 atcggaacat ccactaacca ggcaccactt gaatccacag tatagccttc tggtgtctta
     3601 ccattcacaa gtaattgacc attttctttc aagaagtacc atttatcctt gtctttaatc
     3661 caacctatag ctcgtgaacc acctgtcttg tagaaatacc aatcatttgc ctttttaagc
     3721 cagccttgct tcatagctcc tgattcttct agatagtaat gatgtccagc aacttctatc
     3781 tcacctgtct tcatgatacc agtagaatcc atatagtacc aggcttcttt atcttttacc
     3841 cagcccgttt tcatttcccc tgatggagca aagtaatacc attgcccctt atattgaagc
     3901 caacctgtct tcatagagcc atcaacatcc aaataatacc actgctcttt atcttgaatc
     3961 caaccaattt ccatctggtt ttctttgtta aaataatacc agattccagc gattttcttc
     4021 caatttttag cagcaacacc agagtctgtc aaatagaacc aacgattgtt ccattttttc
     4081 cattgattct gtaataagat acccgtttgg ttaaagtaat accattcacc cttaatttca
     4141 ttccaaccga cagcatattc tcctgtagaa tcaggcgctt gataccacca gtttccatat
     4201 gaactcttat gccaaccagc ttgaaaactt ggaataggct tgtaggaagt tgaaatgttt
     4261 actaaaccgt cttgtcgaat atcaaaaact gttgcatcat agtctttgct ggctgcgttg
     4321 attctctcaa ttcctcgttc tttgagccaa ttaacatact cactatcaac accatttttc
     4381 caaggtagac tatccgaagt ttgaacaatc aaactcggac tcaaattttt aatgaaatcc
     4441 ttggtatttg atttgttggt atcatggtga tgattaaact tcatcaaatc aacttttcca
     4501 atgagaggac catacttgtc ttctgctcca tgaacattat ctaagtcgcc cccaaggtaa
     4561 attttcttgc cattgacttt taccacacta atcaaggaat tggaattatc atcccaaatt
     4621 ttctttaatt cacctgatga atcggtttca ttttcatagt tatagagttg aatatccatg
     4681 tccccaaact gaaaatgagc atctccctgt gtgatgtttt gaataactga aacacctttt
     4741 tctgaagcag tctgtaaaac cttatcataa ccgtacagat tatcccatag acgttcagaa
     4801 ttagtaatac gattatcact atatttttta agatagactc ggtcaactgg ataggtagac
     4861 agtaattcat caacatttcc aatatggtca ctgtgggtat gggtcaccaa aataaaatca
     4921 agtttttgga cacccaattc cttcaaacga cgaaagacac ggtctgttag aacatgctta
     4981 taagacgttt caattccttc tctccatgga tagcgagaat cacttccatc tgggaaatca
     5041 taatcttctc ctgtatccac catggcaaaa tgtccattgc tttcaagaat aatcgcatca
     5101 ctgccacctt cttgaacatt gataaagtgg attttatttc ctgaactttc ttgagcctga
     5161 acattcccat accatgacaa acctaaaaaa gcgcctacaa gtgctaaact agttaatttc
     5221 tttttcattc ttactttctc aatctctcca gggtttcctt aaaaatttct gggatatctg
     5281 ctttaaattc caaggtctta cctgttctcg gatgagtaaa acctaaagtc ttggcatgaa
     5341 gaaattgtcc atgtcctttc aaagtcttgc gaggaccata gacctcatca ccagcgactg
     5401 gatggtcgat ataagccatg tggacacgga tttgatgagt gcgccctgtc tccagttgca
     5461 actctactaa gctataatcg ccaaagcgtt ccaagacatg aaaacgcgtc actgcaggct
     5521 tccctttagc aattacagcc tgtttcttac ggtctttttc actccggcca atcggcgctt
     5581 caattacacc acgatcatta ggcagatttc catgaacaat cgcccaatat ttgcggagag
     5641 actttttatc cttgagttct tgggcaagtg ctagatgcgc atcatcgttt ttagcaatca
     5701 tgagaagacc tgacgtatcc ttatcaatac ggtgaacaat tcccggacgc agaaccccat
     5761 tgataccaga caagtcctta atatgataca tgagggcatt gactagagtt ccactagtat
     5821 gaccagcact cggatgcaca accattccct gaggtttgtt aacgacagcc acatcctcat
     5881 cttggtagac tatttctagc ggaagatcct cagccacata ctctaatacc tctggttctg
     5941 gcacatggta agtgacgaca tcaccctctt ggactgtgta tttagctttc ttgacttgac
     6001 cattgaccaa gacctggcct gatttaattt gttcattcgc aagactgcgt gataattctg
     6061 tcaaatctga caaagcctta tccaaacgca gaccaccagt ttcaatttta atttccattt
     6121 atttcctctt ttagcattgc aatcaataaa ataatcactc caaccgtcag atagctatct
     6181 gccacattga aaattgcaaa gttgataaag tcaaggtgga acatatccac aacaaagccc
     6241 tgactggccc tgtcaataaa gtttccaaga ccacccgcga ttatcaaagt caaacccaag
     6301 accatccaga atgagtcctc catgtgttta tgtaaatacc aaatggcacc tatcacgaca
     6361 accagagtaa tgacagcgaa taacagctgc tgatcttgta agatagaaaa ggctgcacct
     6421 cgattttgca ggtaggtcaa gctaacgaaa ttgggaatcc aggagcgcac ttcacccagt
     6481 ggaatctgct ggacgatata ggatttgacc aactgatcca gcccaattaa aagcagtaca
     6541 atgactgcca ctattgctct ttttttcatg atttcctctt ttgatcaaaa tattcttgca
     6601 tgacttctac gaagagagtc ccagcttgac taagctccac ttcttcacgt ttaacataga
     6661 ccatgcggtt atctaggtta tccttgagac gaataactgt aatgccatta acactgtcac
     6721 tatctaaaaa tccagaacct gtcgcatagg cgtccgtccg ctccaaaata ccattcaagg
     6781 tggcacggtc tgtcacatta aacatctgtg agctagcgct ggtatcgaca aagttctctg
     6841 aataataaag gtactcgtct ttctcttgag tgaaacgaac cgttggtaaa tccgctaaat
     6901 cctccatgac taattcctct ttctgggcta aaggatgacc ctcacagaga taaatatggg
     6961 tatggaaagg aatcaattcg atgacctcca gacctaactt ttcaacccgt tgcataatcc
     7021 cctttttatt ttgattgttg aggtagataa tcccaatctc actatgccct tgcgccactt
     7081 catctaatat ttgaacagta gttgattcaa aaatacggaa gttcttatag tcaggatagc
     7141 gctctgaaaa ggccgtaata gttggtggta agaagtcata gtgctggcta gcaacggaaa
     7201 attcatcttt ttcttcttca ggattggcat actgattttg aaaaatatca aatcctttaa
     7261 ccaattcttg cgctttttca taaaattcca tcccacgacg ggtcaagaaa gtccctgagc
     7321 tggtccgacg gaaaatctta aagcccaact ctttttccaa atcacgaaca gaaatagaca
     7381 gactcggctg actaacatac atcttttcag cagcttcacg aaaagtacca ctattggcaa
     7441 tagccacaac atagcgtaat tgttgaatgt tcatcttcta cccccaactt ctttatcttt
     7501 tcattatacc atattttaga agttttccaa aaaggaaaaa agaacatcct attcttctta
     7561 actatcttca ctatctgcct ttctcacgcc aatcttattt tcaaaatcaa ttcaaaaaaa
     7621 taagtggcta cacaccactt cagtatcgga aagaaaaacg ttgactattt gtgaaaaaag
     7681 aaaatgccgg aaaattccga cattttttta gtaagctaac ttcctgaaaa taggagtaac
     7741 cacacatccc agaaggcagt gatattgatg agaatatgaa ctagtattgg atagtagaga
     7801 tttttagtca tgcgatacaa tagagctaaa ataagacctc cactagcata aatgaaaaaa
     7861 gcaagaggag ttaaagcaaa attgatatga atataaccga aaataatagc agaaagcaaa
     7921 acatctccgt accaaggtga gtttttgaaa aaggttgtca taagcacacc tcgataaatc
     7981 aattcctcag caataggggc gatgaagcaa acgatgagca agaaataagg gaactcctgt
     8041 ctccccatca tttctaccgt ttcattcaaa gaaatctgat ttgaagacag ggatatgaaa
     8101 tacgaaaaga ggaagtcaga catatatgaa atgatgtagc ccagtaaaag gtagatgaag
     8161 tacctcagct gccacttgaa atgaaaaatt ttctttcctg caaaaaccag tagatagatg
     8221 accgctaaga aaagaactcc gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt
     8281 gctggtagat agggctttgc gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa
     8341 aaaattaagg acaatgctag taaaatttga atagcccgtt ttttcatatt aaattctctg
     8401 ctttctccac ttgtttcttc atattactaa taaattttac ttaaaatctc gcagcacttc
     8461 ctttgcaaag atgattgcct cctccaatat atcctaaatc ataggtgcct ctgggacaaa
     8521 atccatgaac cggcagagtt aatactggtt ctatttccca atcgtaccta ccattaggat
     8581 ttttaccata tggatctgct ccaccttgta tcagctctaa ttcttcattt gttagattta
     8641 tattttttgt cattaaaatc atgatatatt tcctccatta ttcttcagat tagttgagta
     8701 atctgatact catacctact tacaaaaaaa ctattatatt aagttggttt tttaatttgt
     8761 ctagttgcaa cattgacaaa catagtatag catatctttg ccaaatatcc tcttcaaatc
     8821 atgaattgtc atcaaaacat cttaaactat aaaatcaatt agtctcaagc tttctatcaa
     8881 tttcttctcc aaaatatgct ataataatag caaaagataa agaaggaaga cctatgatta
     8941 aactactagc cttggatatg gatggaaccc tcctcaatga agccaaggaa atcccacagg
     9001 ctcacatcgc tgctattcac caagccattg aaaaaggtgt caaactggtt ctctgtacgg
     9061 gtcgccccct tttcggtgtc ctcccctact acaaaaaact gggactcgac ctccagaatg
     9121 agtatgtgat tgttaacaac ggttgttcaa ctcaccagac tagcgactgg ggcttggttg
     9181 actggcaaga acttagtcca gctgacatcg aatacctcta tgaccttgct gaaaagagtg
     9241 atgttcagtt gacacttttt gacgagtcac attattttgt tctcggtggc aaacccaatc
     9301 aagttattga aaatgatgct aaactagtat tttcagacct gactgaaatt tctcttgaag
     9361 aagcgactag tggaaagtta cggatgttcc aaggtatgtt tttaggaaca aaagaacaaa
     9421 cagacgattt tgagcagcgt tttgctgaag agctttgcca acgattcagt ggagttcgtt
     9481 cgcagcctgt catttatgaa gcaatgccgc ttggaacgac aaaggctact gctctttcac
     9541 gactagctga gattttgaag attgattcct cagagattat ggccatgggc gatgctaata
     9601 acgatatcga aatgctccag tttgcagggc ttgggattgc aatgggaaat gccagcgatt
     9661 atgtcaaatc tcttgcggat gccgttacct caagcaacga agaagacggc gttgcgcgtg
     9721 ctattgagaa atatattcta taaaaaagaa aagcaaatag acagaagtta ctgctatttg
     9781 cttttttgct aatattttaa aatacggact aatcaataga caagaatagc gaatcataaa
     9841 aatcgattta ctagatgcca tagtatctta tagttgctaa taagaagtta gtctagcaga
     9901 atgaatctct catttctccc acactaatct gtaatttgtc tatacatttc tggtcttcta
     9961 tctcgaaaca agccccagtt taggcgttca cttgctccct tgtctaggtc ataagtagct
    10021 aacagaacag cttcttcttg tctttcagct cgttctagaa tagctcctgt ttcatccgtc
    10081 ataaaggagg aaccgtagaa gtcaagactg gaactctgtc cgccattttc ctcactagga
    10141 gtaacctcct ctaaaccata acgattggct gcgatgactg gaacaatatt cgctgctgcg
    10201 tgcccttgca tagtacgttg ccagtgacca caactatctg tatccaaaat cggctctgaa
    10261 ccgatggctg ttggataaaa gagcaattct gccccattca gagcaagaca gcgggctgtt
    10321 tcggggaacc attgatccca acagataccg ataccaatct tagcatagcg agtattccag
    10381 accttgaaac cagtgttacc aggcgtgaaa tagaattttt cttgataata atggtcatct
    10441 ggtatgtggg tctttcgata aacgcccaac acttccccat ctgcatcaat gacggcaata
    10501 gagttataca agacattacc atctttttca tagaaactga ttggtaaaac aacttgtagt
    10561 tccttagcaa tcaccttaaa atgctgaatg gcagtatttt ccgctacaga ttgggcatac
    10621 tggtagtagt catactgacg ttcctgacag aaatagggat gttcaaacaa ctcgggcaag
    10681 agaataattt gggctccttg ctcagcagcc tgacgtacta aacgctctgc ggtttggata
    10741 tttgttgcca catccttagc gcattgcatc tgaatggttg caactcttac atttctcatc
    10801 tttttctcct attctggaat ttgttgggtg atacagtgga tattgccacc acctaagaga
    10861 atatctctgg ctggtattcc gacaacttta cggtctggga aacacttgct gaggatatct
    10921 aaggccactt ggtcgtttac atcctcaaac tgtggaacca agacagcctt gttggcgata
    10981 taaaagttta cgtaggaagc tgctagtcgt tcacctgcgt atcgcttttc ttctccttct
    11041 tcatagatgt agcctggcaa atcttcttct gtcacaactt gtcgaactgc agggataggc
    11101 aatttatgaa tggtgaagtg acaacctttt gcatctgttt cctgttctaa gagttcgaga
    11161 tctgcttttg acatggcata ctggggatca ttttcgtcat ctgtccaagc caaaacaagc
    11221 tcagcaggac caacaaaggc agcaacatta tcgacgtgtt cattggtttc atcctgataa
    11281 ataccataag gaagccaaat aactttttca gcaccaagac tttctaataa tgtgttttca
    11341 atctcctctt tagtcaggtt aggattgcga ccaggactaa gcaagcaact ttcagttacg
    11401 agaatagttc cttgaccatc gctatggatt gcgcctcctt ccagtacaaa aggtttagca
    11461 tcatagacag gccttcccaa ggcctcagca aaacgactgg ctacttggtc atcctcttca
    11521 taatcttgat aaagaccatc ataggtgcct ccccaagcat tgaaggccca atccacggct
    11581 aatttcttac ctttatcatt gacgagaatg gttgggccag tatcacgcgc ccaggcatca
    11641 ttggtgggaa tgtctaaata aacaaccttg tctccaagat aggattgggc ttcagataga
    11701 taggcctgct ccaccaaaag atagactctt tccccttctg ctatggtctc gatgatctga
    11761 gtaaatgctc ttttagcagc ctttccttga aaaggccatg atcctggtcg agtcggccat
    11821 atcatgaggg taccatgatg gggttcgtac tctgctggca tgtgatagcc taattttttt
    11881 ggactgtcca tcatgataat ctccctttaa agtcttgata gccaaaagct ttgagtaagc
    11941 tacagtctcc ctgttcgtcc atgagataga gacttggcaa tccaatacca ttaaaggtat
    12001 tatttttgac aaaagaataa atggccatgt cttgaaaata aagtctgtct ccgatttgga
    12061 ctggattttc aaaactataa tcaccaatca catcgcccgt cagacaggta ttagaagaaa
    12121 gtctgtaggt atgggctttt tcctgtgcct caaagccatt tctcaaagat ggacgatagg
    12181 gcatctcaag tacatcaggc atatggcagg tcgcagaggc gtctaaaacc aagatttcca
    12241 taccgttttc tacaatatct aatacctcag ttgctaaata acccgcatta agcgcaatgg
    12301 cttcaccagg ctcgatatag atttcaagat tgtaagtttt tcggatacgc ttgatttctg
    12361 aaatcagcaa atccacatcg taaccttctc ttgtaatatg atgaccacca cccatattga
    12421 gccattttac ctcatgtaag tagggaccaa actgttcttc tactgctttc aaagttgttt
    12481 gtaaatcatc tactccctgc tcgcaaaggg tatgaaaatg aagtccgtca accaaatcta
    12541 gcaaatcact cggaatcttg tctatagtaa ctccaaagcg agaacctggt gcacaagggt
    12601 catagagcgc gtgatctcct tgagttgaac actgagggtt gaggcgcaaa ccaacactga
    12661 caccagcctc tcgacaacgc ggaccgtgtt tacgcaactg tctctctgag ttaaagacga
    12721 tatggtccat tatctctagc aattcctcca agtctgcatc cttgaaagca ggcgcaaata
    12781 catggacttc accaggaaat tcttcccttg ccaatttggc ctcatagagt ccactagctg
    12841 tcgtacctga tagatactgg ctaatcaagg gataagtttt gtagagggaa tatgccttct
    12901 gggcaagcaa gaccttgcaa ccggcctctt cttgtacata ttgtagaatg cggcaattag
    12961 cttctaactt ggccaagtca ataacatagg ctggtgttgg tacttgttct aacttcatta
    13021 gtccaccatt tgtggatttt caaccacaac ccatggcaaa ccatactcat tcaaagcttc
    13081 catgaatgga tctggatcta actcctcaag gttatacact ccagcttgtt tccaagttcc
    13141 gttcatgact aattttgtcc caatcatggc tggaacgcct gtcgtgtatg aaattgcttg
    13201 tgacccgact tctgcatagc actcttgatg gtcgcaaaca ttgtagatgt agatagtctt
    13261 ttcaacgcca tctttgacac ctgtaaagat acatccaata ttggtttttc cgactgtacg
    13321 tggcccaaga ctggcaggat ctggaagcaa ggctttcaaa aattgaattg gaacaatttc
    13381 ttggccgtta aagttaatgg tatccgtacg aaggagtcca acattttcaa gacatttcat
    13441 gtgcgtcaag taagattgac caaaagtcat aaagaaacga atgcgtttga cacctggaat
    13501 gttcttggcc aatgattcga tttcttcatg gtgaaggaga tacatatctt tttgtccaac
    13561 ttgagggaaa tcatactcac gcttgataga catagcttcg acttcgaccc atttcccatc
    13621 ttcccagtaa gaacctggag cagaaacctc acggagatta atttctggat taaagttggt
    13681 tgcaaatgga taaccgtggt caccgccatt acagtctaaa atgtcgatat aatggatttc
    13741 atcaaaatag tgtttgaggg cataagctga aaagacacta gttacacctg ggtcaaaacc
    13801 agaaccaaga agagcagtca agcctgcttc tttgaatttc tcttgataag cccactgcca
    13861 tgagtagtca aagtaggctg taaaaccaag ttccttacaa cgtttttcgt agatagcacg
    13921 ccactcaggg tcttctgtgt cttctgcttc gtagttggct gtatcgatat agtgaacacc
    13981 tgttgccaaa caagcatcca taatggttaa atcttgataa ggcagagcta cattcaaaac
    14041 ggcttctggt ttgtagcttt caatcagggc aatcacttct tcaaccttgt cagcatcaag
    14101 tgctgcagtt tcaattttag tacttgtttt gccttctagc ttcgctttca agtcatcgca
    14161 ttttgacttg gtacggctag caatcataat ctctgtaaat gtttcgctat cttgacaaat
    14221 ctttgaaata gcaacttggg caacgccccc acaaccaata actagtaaac gactcatttt
    14281 tttccttcct cttcttctaa aatgtcctca acatacttgg gcaacataaa ggatcccacg
    14341 tgtaagtttg cagtgtagta ttctgtgaaa agctggcgtt ttttccaacc ttccttgtca
    14401 aaatctttga cagggtggta ttttttcgat gcaaatccaa acaaccaata gccagctggg
    14461 ctagttggaa tatgggcctg ataaacccga ctgattggaa aggattgatt gaccttgcgg
    14521 tgcatgcttc ggcaggccga ctcatcctcg tcaaagaagg gactcccatg ctggtaaatc
    14581 atgatgccgt cttccttcag agctcgataa ctattgccgt agaattcctt ggtaaagagt
    14641 ccttccgtat ggccaaatgg atctgtcgca tcgttgatga taatatcgta atcatcttcg
    14701 cagtttcgca aaaagcgtag cccattttgg tagtaaatgg taacacgagg atcatctagc
    14761 cctgcagcaa agtctgggaa atactcacga cagacctcga ccaacatctc atccggttcc
    14821 acgatatcga tttgttccag ttcaggatag agtgttaata cttgggcaac accgccgtca
    14881 ccacccccaa taaccaatac tttctttgga tttgggtgga cagccatggg aacgtgaacg
    14941 gtcatttcat tgtagacgaa atcatccgca tctgagaaca agacatggcc atttaaaatc
    15001 agtattttcc caaaagctgg cgtatccaag acttcgatat cctgccattc actttttcca
    15061 gcgtaaagtt gcttggctgt tctcagagac aatttgacat ctggagtatg aacttcagaa
    15121 aaccataaat ccatctattt ctccttatat tatatttagc gcagttagct actgccaaag
    15181 cccaagtggt atacttggaa taagccactg tggattagtt tattccctcc aatcgcttga
    15241 cgatttccga aaggctctaa ccacagtttt ttgtttcaat tggtaatgag tttgataacg
    15301 catagacgtt ttatctcgtc taaggtaaca agacaaaaaa ttcgtggata accaagtaga
    15361 cttgaaatac tacatctgga ggtactccca tgctttatgt gggcattgat gtcgctaaaa
    15421 ataaacacga tgttacagcc ttgaatgttc caggaaaaac tgttcttaaa ccactcactt
    15481 tttcaaataa taaagctggt tttgaactct tagatctgtc tcttcgacaa ctcaaccaag
    15541 actgtctcat cgctcttgaa aataccggac attatgcctt taatctactg aacttcctgc
    15601 atgaacaagg atataaagtt tacacctgca atcctttgct catcaaggaa tttgccaaat
    15661 cattatcact tcgcaagact aaaacggata agaaagacgc tcatggcatc gctcttaaac
    15721 ttctttctga ccccaatcgt gaacaatttc aacacgataa tcggcaagta gaactaaaaa
    15781 tactggctag acatattcat cgtctcaaga aaaacagtct gattggaaag tacaatacac
    15841 tcgttgtctt gatatcatct ttcctgagtt ggataaaatc gttggaaagc attcagaata
    15901 tacctaccaa ctcttgacac gctaccctaa tcctcagaaa aggattgagg caggatttga
    15961 taagctgata gaaattaagc gattgaccgc ttctaattca agggcttttt gccgtgctct
    16021 aaaatcatcg ccaaatcatc aaattgaaat aagaaatagt ttagataaaa ctattgactt
    16081 ttcttatagt ttgtctttct cttaataacg ttgatatgat tgacctctgg atcttccgtc
    16141 ccttggaggg agcaaccacg ttccttggcg aattggatat agtctacaat ttctcgtgta
    16201 atgcgttcac caggagccaa gataggaatc cctggaggat agcacatgac aaattctcca
    16261 cagacctgtc caacagactc atctaaggtc aaactttttc tctctgaata gaaggcttct
    16321 tgtggagaca gcaccaactc gggctgaata tattctccag ctattaagtc cttcccatct
    16381 cgtgaataga gtctcttaat atcagccaga gcaccaacca agcgctcgat gtcttggatg
    16441 cggtcgccga tggaaatata ggccaagata ttgccgatat caccaaactc gatctgaatg
    16501 tcgtattcgt ctcgcaagag gtcataaacc tcgatacctg ttaagcctat tccctgagtg
    16561 taaactgaca acttggttac atcaaaatca cagaccgaca caccatctat taactctttt
    16621 gagtaagcat agtaaccgcc aatggcattg atttcatgac gagcgtactc ggatagctca
    16681 atgacttcct caaacgactc tttaccacga agggccaagt tgcgacgtga aatatccaaa
    16741 ctagccatca ataagtaaga ggcagatgta gactgggtca ggtttataat ctgacgaacg
    16801 tactcgggat tcatctgctc cccgattaaa agaagcgaac tttgtgtcaa actcccacca
    16861 gacttatgca tggaaactgc tgccatatca gctcctgcat ccatagcaga aattggaagt
    16921 ttaccagtga aatgcaaatg cgctccatgg gcttcatcta ctaaaaccat catgccagct
    16981 tcatgagcca tttctgtcaa cccctttagg tctgaacaga tgccgtagta agtaggattg
    17041 ttgattagga tagccttagc atctggatgg tcctttatgg cctgtgctac tcggtcattt
    17101 tcaagaccta aagcgatacc aatcttagga tctacactca tctcgatata gatgggaatg
    17161 gcaccacata gaaccaacgc attgatagca gatttatgga catttcgtgg cagaataatc
    17221 ttatctcctg ccttgcaggt tgccagaatc atagtctgca ccgatgaagt tgttccacca
    17281 atcattagaa aggcatggct agctccaaaa gcatctgcag ccagctcctc tgcatcacga
    17341 ataatcgaaa taggatggcc taaattatcc aagggtttca tcgaattgac atcaatgcct
    17401 acacattttt ctcctaagag ttcgacaagt tctggatttc cccgtccacg cttgtgacct
    17461 ggaacatcaa agggaacaat ccttttcttg cgtaacttca ccaaggcctc ataaattggg
    17521 gcttggtttt gatctacctc tttcaaaaca tactcctttc aatattttta ggaccttatg
    17581 aaaactaagg aactaaaggt tgactcatga aaaaagagca ggttttcacc tgctctgcaa
    17641 tcttctgacg tgtttatttt ggtttctgtt gagtatgtct gttcccgatg tttcctaact
    17701 ctctagtagc aaatattacg tactttattg atcgtttcac aagatgacgt gtgctttcac
    17761 cacactaaaa atttatgaat taggacaagt gtcctaacat caacttataa aagtaggctt
    17821 ttaaccctat caataatgtg gcttttcaac cacgcttcgg cattcaaccc tgcctgtccg
    17881 taggcatttt ttactcgggt ttatatttgc tagaaaacat catctcattt tctaagcttt
    17941 attactatat catgttttta agaacttgta aagtattttt tgataaaaaa caaaaatata
    18001 atagattgaa actagaatag tacacttctg cttctaaaac attattagaa atagatttta
    18061 ctgtcctgat cgatttgttc tgttcttgtt tcattttact atatgttcgt aaatgaaagt
    18121 tctataatga agttagccac ccagccctcc taaaaattag atggttcaac tagctga
//
LOCUS       DAVBNZ010000042        18138 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000042 DAVBNZ010000000
VERSION     DAVBNZ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.042"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ860_001515"
     CDS             complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ860_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3119924.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYTENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQA"
     gene            complement(881..1867)
                     /locus_tag="VQ860_001516"
     CDS             complement(881..1867)
                     /locus_tag="VQ860_001516"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET3119925.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1830..2630)
                     /locus_tag="VQ860_001517"
     CDS             complement(1830..2630)
                     /locus_tag="VQ860_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET3119926.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2880..3260)
                     /locus_tag="VQ860_001518"
     CDS             complement(2880..3260)
                     /locus_tag="VQ860_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3119927.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ860_001519"
     CDS             complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ860_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET3119928.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ860_001520"
     CDS             complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ860_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET3119929.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ860_001521"
     CDS             complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ860_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET3119930.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4508..4639)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4805..5989)
                     /locus_tag="VQ860_001522"
     CDS             complement(4805..5989)
                     /locus_tag="VQ860_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119931.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            complement(5993..6580)
                     /locus_tag="VQ860_001523"
     CDS             complement(5993..6580)
                     /locus_tag="VQ860_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3119932.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6613..6801)
                     /locus_tag="VQ860_001524"
     CDS             complement(6613..6801)
                     /locus_tag="VQ860_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119933.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            complement(6980..9220)
                     /locus_tag="VQ860_001525"
     CDS             complement(6980..9220)
                     /locus_tag="VQ860_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET3119934.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSFQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQQGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGVDSW
                     KIESVR"
     gene            complement(9204..9854)
                     /locus_tag="VQ860_001526"
     CDS             complement(9204..9854)
                     /locus_tag="VQ860_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET3119935.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9922..10491)
                     /locus_tag="VQ860_001527"
     CDS             complement(9922..10491)
                     /locus_tag="VQ860_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3119936.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10668..11779
                     /gene="ald"
                     /locus_tag="VQ860_001528"
                     /pseudo
     CDS             10668..11779
                     /gene="ald"
                     /locus_tag="VQ860_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12146..12406)
                     /locus_tag="VQ860_001529"
                     /pseudo
     CDS             complement(12146..12406)
                     /locus_tag="VQ860_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12409..12909)
                     /locus_tag="VQ860_001530"
     CDS             complement(12409..12909)
                     /locus_tag="VQ860_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3119937.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            complement(13089..14057)
                     /locus_tag="VQ860_001531"
     CDS             complement(13089..14057)
                     /locus_tag="VQ860_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET3119938.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQDKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14143..14358)
                     /locus_tag="VQ860_001532"
     CDS             complement(14143..14358)
                     /locus_tag="VQ860_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET3119939.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ860_001533"
     CDS             complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ860_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET3119940.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ860_001534"
     CDS             complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ860_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET3119941.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15847..16584)
                     /locus_tag="VQ860_001535"
     CDS             complement(15847..16584)
                     /locus_tag="VQ860_001535"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET3119942.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ860_001536"
     CDS             complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ860_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET3119943.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
BASE COUNT         5187 a         4136 c         3376 g         5439 t
ORIGIN      
        1 gcttgactat gagaatcgta gacccattct ttttcagcta ttttcccatc aaatttgaga
       61 taaaaccaag attccttatc ccaaatccat tcattggctg ccatgtagcc accagatttt
      121 agataataat agtgaccatt ctcgaaaatc cattctttat cagcatagtt tccattttct
      181 tttatgtaaa accaagattg gtattgtttg tcaaaaagcc aaccttgctg tactttggca
      241 ccactagcat tcacataagc ttgattaatc cactgacttg ttagtagata accaccggat
      301 ttgaaataat agtccttccc tttaatttgg agccattctt tctctgcgtg ctgtccatct
      361 gctttgatat aaaaccaagc atcgtattga gaatcataga cccagtcttc tattactttg
      421 gcacctgttg caccaacata ggaagttcct acccaagcat ttcttttcat ctttccatct
      481 tggtcaagat aataaaaggc tcccttgtct tctacccatt ctgatttggc catatagcca
      541 ccagatttga ggtaaaaata gtcgtcacct tgctttagcc attcattttc agtatagtta
      601 gcatctgctt ttatatagaa ccaagattga taatgagtat caaaaaccca ctcattcgct
      661 gcttgactgc catcttcttt cagatactgt tttccttgcc aagtaccatc actagccatt
      721 gcaccctctg gactagctaa gaaaaatagc agagctaaaa aaataaatct tactttcttc
      781 attaaccttc ttcctctgtt cttatttatt ttattgtacc aaaattctcc taaattcata
      841 ttacaaacta ataaaaaatc aagaacagat tgattgcagt ttacctcaga gactctttta
      901 cttcctgacg gagttcttcc agactgctaa taccgtattt atccatgact tttggtaaat
      961 tttcgatgat gtcagggcag gcataaggat tggtaaagtt agctgttcca actccgatag
     1021 cagatgcccc agccagatac atttctaggg cagcttcagc cgaatccact ccccccattc
     1081 caatgatagg caggtctgtt gtttgggcta cttggcggat gagtttgagg gctactggaa
     1141 agactgctgg acctgacatt ccacctgttc cattggccaa gattggtttt ctggttttga
     1201 ggtcaaagcg cattccaacc agagtattga tcatggtcaa gccacttgct cccgcatctt
     1261 ctgcagcttt tgcgacagta acgatatcgg tcacactcgg ggttaatttg acataaactg
     1321 gcacttctga ggcttccaca gctgctttca ccacatcata agccaaatct ggatcttgac
     1381 caatcaaaag tccatgatta cagtggtcaa cattgggaca agaaatattg agctcgatag
     1441 cttttacatt agttgccttg gaaatcccat gagaaacagc tgcatactct tgttttgaaa
     1501 aaccagctac attggcaata ataggaagat ttggatattc tctttccagc caaggtagct
     1561 tttcagccaa aacaacctct aaaccaggat tttgcaagcc aattgcattg agcataccag
     1621 caggcgtctc tgctactctt ggagttgggt tcccaaaacg tggttcaagg gttgtcgcct
     1681 tgatcataat agaacctaaa aggtttaaat catagtactt ggcatactct tgtccaaagc
     1741 caaaacaacc tgatgctgga ataatcggat ttttcaaatc caaaccaggt agagacactt
     1801 gtaatcgatt tgtagtcata attttctcct tataatacaa ctgttcctgt gcggaaaaca
     1861 ggaccatctt cacagacgcg ttggctgacc gtctcgcttt ctggtacttt tagaacacag
     1921 gcatagcaag ctcccatccc acaagccata cgagattcca gagataaata ggctcttggg
     1981 tgatcatcaa aggtttgatt gatatacttc atcattcctg gagccccaca cgagtaaaca
     2041 gcatcaaact gactatctaa atcattgata acaacggaaa catttccctt gatgccataa
     2101 gaaccatcat ctgtcgttac aaagacctga ccatactgag ccaattccgt tttcaaaata
     2161 acagcatcct tattagcaaa accgaggact gtcactactt tcactccacg ttcatgcaat
     2221 tccttggcca cctcaagcaa gggtggaaca ccaatcccac caccaacaag gagaacctga
     2281 ttctgctcat caaggtcaga caagtcaaaa ccatttccct gaggccccat cacatcaaga
     2341 gtgtctccct gacttaaggt tgaaaaaatt gcagtcccag ctccctcaat ccgataaatg
     2401 aggtgacact gcttgtttgc cttgtcaata gacgaaattg aaataggacg acgtaagaga
     2461 tgggcatcgt ccggtacacg cagatgaaga aattggcctg ctcgcatggc ttcaaccatt
     2521 tctccttcta ggactaattc aaagattgct ggcgcgattt cctcttgtgc aaccaccttc
     2581 atggtttcca accgaatgac acccaaacgc ttcttacatg tgggattcat aacttttcct
     2641 ccttaaattt taaggggacc agataaagaa aagaccttgc tagtgcaagg cctcagttaa
     2701 aatcgtacaa cacaagagag cacactcaaa aagtctcctc tagaaaattg cactattctt
     2761 ttatctgaca ccttgtgagt ctctctggac tccccttaaa ggttgaattt ttattagtat
     2821 actctttcag ctaaaaaaag tcaagtagaa aacgaatatt ctacttaact tgcacgaaat
     2881 tatttttcac gaatgacttc gaccttatat ccatcagggt ctttgacaaa gtaatagttt
     2941 ggtgtagttc ctggtagacc atttggctca gtcacttcat agccttttgc actgtgttct
     3001 tgatgaagtg cctcaagatc aggtgtactg agggcgatat gggcaaaccc atcaccaacc
     3061 acatacggac cgtgatcgta gttataagtc aactccaact catagtcatc accctcaaga
     3121 cctagataga caatcgtgaa ggcatggtct ggaaaatctc tgcgacgcaa ttctttaaaa
     3181 ccaaaagcat cttgataaaa tgcgattgat ttttcaagat tttctactcg taagcaagtg
     3241 tgtagcattt ttgaagccat atttttctcc tttattttta aaaagactgg acaatcctgt
     3301 tccagtctca tcagttgtta tttaccaagt tttgctttag ctgcatctgc aagagctgtg
     3361 aaagctactg catcgttaac agccaagtca gcaagcattt tacggttaac ttcgatctca
     3421 gccaatttca aaccatgcat caattgtgag tatgaaagtc cgttcatacg agctgccgca
     3481 ttgatacgag tgatccacaa tttgcggaag tcacgttttt tctgacgacg gtcacggtat
     3541 gcatagtagt aagagttcat tacttgttct tttgcagtac ggaacaagat gtgtttagct
     3601 ccatagtaac cttttgctaa tttaagaata cgtttacgac gtttgcgtga tacaacgcca
     3661 cctttaacac gtgccatgtt ttatttcctc caaatatttc ctagaattgt ttacttacag
     3721 tcaagctatt atttcaagcg agtaagcatt gctttgatac gtttgtaatc tcctgaatgc
     3781 accatagatg ctttacgaag atgacgacgt tgtttcttag tttttccgtg gaaacggtga
     3841 gaagtgtaag cacggaaacg tttaagtcca ccagaacctg tacgtttgaa acgtttagct
     3901 gatgcgcggt gtgttttttg ttttggcatg attttttctc ctttatttaa ctttctgaca
     3961 attatttttt gtcagtcgct ggcgccaatt gcatgaacat ttgacgtcca tccattttag
     4021 cacgttgttc gatgatggca atatcttgag ttgcttcagc aaactcggct aaaacttttg
     4081 caccaatctc tttatgggta atcatacgac ccttaaagcg aatagatacc ttaactttat
     4141 ttcctttttc aaggaactta cgtgcattgc gaagttttgt atcaaagtca cccttgtcaa
     4201 ttgttggact tagacgaact tctttcacag taacaacgct ttgtttttta cgttgttctt
     4261 tttgcttctt ctggtactca aatttgaact taccgtagtc cataattttt gcaacaggcg
     4321 gtttggcttg gggttgaatc aatactaggt caacattagc gttatcagcc aaagcttgcg
     4381 cttcactgag tggcttgatg cctagctgtt ctccttcaag accaatcaag cgaacttcac
     4441 gtacacgaat ctcatcattg atgaataagt cttgctttgc tatggttttc acctcttttg
     4501 ttttattaga gaaaaacaat agcggactcg taaatataca agcccgcacg ttatgatagc
     4561 gtttcttcga aacttttcat ccgtagggcc aggcaactta atgtcacaag gcgagaagct
     4621 ctcacttctg cttttctcaa cttctatatg ataccaagtt ttctagctct tgtcaagata
     4681 aaaagttatt ttttgaaaag tttgtgtttg tgtttgtatt ttggtttggt tttcgaatca
     4741 aaaagagaga atcaagttga ttccctctct atgttagttt ttccttaact tccttataag
     4801 aatgctaaga cctattaaaa acttcctttt tacgtgaact tccccagctt tcgataaata
     4861 gaatccccac tagcaaaagg ataatcaggc aaggaagtaa gaccatcccc atgctccaat
     4921 ttagatcgac attatcaatc tgcttagata atcttccaga taaaatctcc actgaacgca
     4981 agtaagtaaa gggaatcaga tgtgcaatcc tttgaagagg ctgaattgtt tggatgccaa
     5041 acaataagcc aacaatccca atgagtgaaa gaaagaggac aggcattttt tgcttgaaaa
     5101 agtaagcaat caagtacaca acttccacaa tgacgataaa ggctaagaaa gctaagagca
     5161 agccaggaaa taatacatct tgtattttcc caatagttac ttcttgattc actaagctat
     5221 aaattgggta gggataatct aactgtccaa aaccacttat cagacttccc actagaaaag
     5281 aaaagccaca gattccgata aacagcacag ttacatatcc cactccaact ccaagagagg
     5341 atattgcaaa tgtcactttt gaaacaggat ataagtgagc tgtgtccaga tgattttgat
     5401 atctttctgc aaatagttgt gttagcataa aaataatcgc aaccacaaac aagcttggga
     5461 tgataacctc taaaatccag acaatctgat caatcccgtg ggtcggaaac tccaaagtat
     5521 gtgcttttat gttcaaggga tacagggctt ggtaaatctt ccgttcgcgg tcaaccccca
     5581 tttttaagcc agagctagca gtcgggtcat ttgatacaaa ttcataattc ttctcttcat
     5641 cttgccactg cagatagtag gcttctttcc agcgcccttc ttttagtaaa gttagaattt
     5701 ctgtctttcg cgtcaaaaga tttttttgca cgtctaaatt atttttagca aactggtatt
     5761 cctccgagct ggtatcagac atttgggaga gtttctcttc attttcattg atagccctct
     5821 cgttggctgc aatgcgactt tccaacctgc tctccaagct gtgtgagttt gcagtctgac
     5881 tatttaaata aaaggtaaca ccgagtacag atgcaaataa aagtaagata atccagttta
     5941 aacgactttt gaaaactttc tttaacaaaa atagactaac atctttcata aactaaacct
     6001 cttctatctg cccctgatga atggttacta ctctatcgca gacatcaacc aactcttcct
     6061 tatagtggga acttaaaaga accagctgtt cttgtctatc gatttgtgct agcctatcaa
     6121 aaaacttctg tcgataatac tcatctaagc catttgtaat ctcatccatg agccagcatt
     6181 tggcctgact gaggaaatac atggcaatca ccaagcgttg cttcatgcct aaggaatact
     6241 tgcgaatggg aagactgata tagtcagaca tttcccaata ggcgatttca tccctcaagt
     6301 tcagacctga cttccagatg tttttgataa gacgaaggta gtccatccca cttaagtttc
     6361 catccagcca ttcaatactc tcataataaa ataaagaagg aggggctgcg atatttccac
     6421 tacttatggg aattaaattg ctaatggcac ggaacagggt cgtctttcca gagccattga
     6481 tagcaagaag accataaacc ctaccctttt taaaggtgaa atccacatct tgcaagatga
     6541 cttgtcgcgt ttttaaggtc acatgagtaa gctgcaacat atctagccct cctttttctc
     6601 actctttaag aattaatagc ctccgctgta atagtttatg acctcataac gaccgtagtt
     6661 ccagcctccg ccaactttat actcagaata gctgtcataa cgagaccatg acggaatcca
     6721 agcatactga tggtcgtgat agttggtact atattcccaa accgtattcc aatcatactt
     6781 gtaactttta gtgactgtca cagcagatac actggactga agaagaccaa tagattataa
     6841 actaactaat taaacgattt ttgctaattt ttaatgattt tatatcctca atattgaata
     6901 cgttttcatt ataccatttt tatcattatt atgcaacaaa tttttagttt atttcactaa
     6961 tctacaacat ttatccttcc tatcgaacac tttcgatttt ccaactatcc acccccttaa
     7021 aacgtatagc tccttgctgg tcagttcgat aaactttgct attgatacct tccagtcgtg
     7081 tcaatgtttc ctgatggggg agtttcattc gattgctctt tccaactgag ataagagtaa
     7141 gctctggttt gagtttttct agaaaggctg gacttgatga ttttttattt ccttgttggc
     7201 tagctttcaa aacatttact ttcaagtctg gatagtgctt cagcaagtcc ttctctcctt
     7261 tctcctccaa atttcccgtg aagagaaatt gcttatccaa gaatttccca tacagaacta
     7321 gggtatcatc gtgtcctcca tctcccattt tccttggaga tagaacttct aactgacttc
     7381 caaaaatggg caagttctcc cctactgtca tactacgcac ctttgtttga gtcgcctgta
     7441 gttctgccac aaattccttc tgtttcagac tgtcttttga tactagaatc tcccctacat
     7501 ggaaagcctt ggtcacctct gacaaatctc caacattctc cttgtccgtg ttagtcaaaa
     7561 ttagctggtc aatcttagct actcctcgac ttttgagata gggaatcaag gttcgctggg
     7621 cattgctggt cgtcatcttt tcttgccatt tttcgatttt cttataagat tctgccttac
     7681 cacctacatc tatgagaatg gttttcccag ttacatcccg taggaaaata ctttctcctt
     7741 gccccacatc cagcatggtg atttcatttt ccagtggata cttggtaagg aaaaagagac
     7801 ctgtaatcaa taaactcaat actgttaatc ctttaatgtt tttcctcaaa tcatagacca
     7861 aagccaagga aattaacaat aagattaaaa gccatgcgtt gggttgacca aagacaagcg
     7921 gtctccttgc cacctgcgag accaagcgaa taatgccctc taaccattca aagataaagt
     7981 tcagctgaat gactggatag agaaaggaaa ggacaaataa gatagacaag agcggtaaga
     8041 agaccaagtc aaaaagaaag gaaaagacaa aggtcaaaag gatagaccaa ggttgaaatt
     8101 ccgcaaaata gaaggataga atgggcaata tgcccaagga gatgactaga ctttcactag
     8161 taacagcctt gagcccctcc ccttctttgc tggtcatggt caggataaaa gcataagcac
     8221 aggacaagac tcctcctgct gtcaagaaaa agtttggcat gacaataaag aggacaagca
     8281 ccgtcaaggc aaaattatcc aagcccttaa ccccatgttg agccagtagc ttttgcaaga
     8341 gactgcgaat aaccgatgct gaaaatccag ttagtcccgc atagataagg gaaaagggat
     8401 aagtcagcca cttcaacttt tcttgtgtca agcccaatcg taaaagtagt ttcttaaatc
     8461 cgtccatgaa aaaccctacc tgcatacctg acaaggcaaa aaggtgaata attcctaaac
     8521 tggaataaag ctcattcatc tcctcaaaat cggtgtccag atgtcctagc aagagtcctg
     8581 tcatgtaatt gcgcataggg tctgggaagt gcatcttaat ccaaaccaca gcctttcgac
     8641 gtaaactgga caggttttca cctatatccc aactgccaac cttttggaat gactggattc
     8701 ttttaatatt gagtgtctgg taaattccct gagtcttcag atagccttgg tagtcaaagc
     8761 caccaaaatt tctctgccct tctggctccg aaagcttccc ttctagtcct atctcatgaa
     8821 ggtcagttaa agcttgaaag gcttctttct cctcctcgga ctggagttta taatagactt
     8881 ggaaagcacg accatcagac ttaccacgaa aggacagact gtcaccgtta accttaatag
     8941 tgtctggtaa aatccgtacc ctttcaacag aatccaccaa attttgactc acttgactct
     9001 gttgccaagt ttgaaacaga aaccagaagc caaagactcc acaaatcact agaactttac
     9061 ctgctgattt ccaaggaaat tggataaaga ggcagactag cagaaaaaca aaacccaaca
     9121 aagcaaaata ggatactgag aaaatggcgt agtaaagcca tagtaacaga aaactcaggt
     9181 aaattagggg aatagagaaa ttcttaatcc actgtaacat agtctttaag tttttctatg
     9241 gtcttggcac caatgccaga gaccttcttg agctcgtcta ctgacttgaa cttgccattt
     9301 gcctcacgat ggtcaataat gtcctgagct cgttttcctc ccagtccctt gacctgcttg
     9361 agttcttcca gactggcctt gttgagattg accttctttt ccttgcttgt tgaagaagct
     9421 gtccccgaac cagtctgttg actaactgct tcttctccct tagtaggaac gtaaaccaga
     9481 gcctcatcac taactttctg agctagattg agcgacttgc tgtctgcttg ctctgtcaag
     9541 ccaccagcct tctgaacagc atcattgact cgactaccta caggcaagtc ataaatccct
     9601 ggcgatttga cagcaccttt gacatctact gtgattagat cttgttcaac tggttcttcc
     9661 ttctcttcct tgttcacttc ctttccggtc gatgagtcct tggaaacagc tgcaacttca
     9721 gcctgcaaat tcgtctcttt gacagatgtt tgtggagctg gctttagcag gaaaaatccg
     9781 cctacaagca agcccagacc agtacagatg acgatgattt tatactcttt gattttctcg
     9841 ataattgctt ccatattttc tcctctctta gattattcgt aagaggaaga aaaaacagtc
     9901 gaaaaatttc ttttcaactg cttatttatt tgcaaaatag tcttccttgg tcaagacata
     9961 atgaactctt gtcacgattc ggcctttttc atgctggtcc atacaagcat atggttctgc
    10021 atgggaaaaa cgcatgcctg atttctccat gacctttcct gacgcgggat tagccttatc
    10081 gtgaagggca gtcaacttat tcatccctat cttctcaaaa gctagctcaa tcacagcacg
    10141 attggcttct gtcgttaatc cttgattcca atacttttta ttgataatgt agccaatagc
    10201 tgccttctta agaacaggat caatcttgtg taagtcaata gttccgataa acttgccgtt
    10261 atcttttaat tcaatccccc aacgtcccaa gggattagcc aagtagaact gagcaatgtt
    10321 attcttggtt tcttccaagc tttgattggt tggaaaagtg taacgtgtat tacccttgtc
    10381 cgaggcatag tcaaacattg cttccgcatc atccaaagtt acaggtctaa gcaataaacg
    10441 ctccgtttct atagacggat actgggcaaa tttcacaaat attgattcca tacttttccc
    10501 tccattagag cttgattttc actagtctag cataaaaaaa tttggatgac aagtttttct
    10561 tgatttttga agcggtttca tatacaatga aaccgtcaca tttttgattt atgaactgga
    10621 atgtgacaac caaaacaaga ccgtcaattg aaaggtaggt tatctcaatg ttaatcggaa
    10681 tcccaaaaga aattaaaaat aacgaaaacc gtgtcgccct cacacctgca ggtgttcata
    10741 gcttagttag tcgtggtcat cgtgtcctta tcgaaacaaa tgctggtctc ggttctggct
    10801 ttactgatgc tgactatcaa aagcaaggag ctgagattgt cgctactgct ggtgaagctt
    10861 gggcagcaga gttggttgtg aaagtaaaag aacctttaag ttctgaatac ggttacttgc
    10921 gcgacgatct tcttctcttc acctacttgc acatggccgc tgctccagaa ttagcagatg
    10981 ctatgttagc agcaaaaaca acaggaattg cctatgaaac tgttcgtgac aatcaaggac
    11041 aactaccgct cctcgttcct atgagtgagg ttgcaggtcg tatggctgtt caaatcggag
    11101 ctcacttcct tactaagcaa gctggtggct ctggtgttct acttggtggt gtaccaggtg
    11161 ttccaaaagg aaaagtaact atcatcggtg atggtgtcgt cggtacacat gctgcccgca
    11221 tcgcccttgg tcttggtgct caagtgacta ttttagatat tagtgccaag cgtctctcag
    11281 ttctagaaga agtctttgga agtcaaattc aaactattat atctaattca ttcaacattg
    11341 aagcaagtgt gagagatgct gatgtggtga ttggagccat tctcatccct ggtgcaaaag
    11401 caccggaatt ggtgacagat gagatggtca aacaaatgcg tccaggctct gtatcgttga
    11461 cgttgctgtt gaccaaggtg gcgttatcga aacagctgac cgtgtgacaa cgcacgatga
    11521 acccgtctat gaaaaacacg gtgttctcca ctatgccgtt gccaatatcc ctggtgcggt
    11581 tgcccgcact tcaaccatcg ccctaaccaa tgtcactctt ccttatatcg aagctttggc
    11641 tggcaaagga ttcgcacaag caatctctga agatgaaggc ttgcgtcaag gtgtgaccac
    11701 ttatcaaggt tacttgacta gcctaccagt tgctcaagga cttaatcgtg actacactga
    11761 tatcaatgat ttagtataaa ttttgaaaag aaaagggtga cttcgcaagt cctacccact
    11821 gtgctttgtg tcatcagcta ttacatcgtt ggtttattgt actgtatact ttgcaactgg
    11881 agactttcgt tccagactca attgtgcata agaaactcta aattgaataa agtcaacaga
    11941 gtttcgccca accacttcgt cttgtaatga caattatata aaccaaagga agctgagctc
    12001 tttagtccca gcttcttttt atatataaaa ttttacccgt gcaaagacag ggccttagca
    12061 gacttctttt ttacttcgtt cacccttgct ttttcttttt aggtttgggc gttggcagtt
    12121 ggttatacat agctaaaatc aggtcttata gaaacatctt attatcaagt tcttccactc
    12181 aaatcatttc tttggcacct ttgtatggaa actcaaaaga agattggtca atcttatcta
    12241 agactgcttg cacgggttta actaaaaagc gatcgtcata aatgccgcca ataatcttgc
    12301 cgcggaagta aagaatatac tccccaatca tggaacggta agtcacatca tctaatcctg
    12361 ataattgttc caaaacaaat tccaaatagt tcttacttga tgccatttct aatcttctag
    12421 gctctgttca gcgataacaa ccgtatagag ttcttgctta acctcgcatc caattgattt
    12481 aaagccctgc ttttcccaaa aatgctgaga ttgcggattt cccttaacat aagccaaacg
    12541 tgcctttcga aagttcttag caaaataagc tagtgcttct gtcacaatat gactaccaat
    12601 ccctttcctc tgataggctt gatcaaccat aaacaaacca ataaaaacag tctcctcatc
    12661 aggatatgca tagacaaaat ccataacagc cacaaggtca gatccattcc aaaatccaac
    12721 aaaaaactta tcagccttag ctttaccttc aggtagacaa agcatgtcct cttttacagt
    12781 tgcaaaattt ggctctggtg gacaatgctg aaaatacaga ggattacttt catataaaga
    12841 taaaatactt ggaatatcct tttcagttag tatcctacaa ctgtaatact tagatagttg
    12901 gtcaatcatc ttttcaaatt cctactttct tgcgccctgt gattatgaca caggaagatg
    12961 cactgatcgt catcagccac ataaaagttc tttccatcgt gcctaatcgt tgtctcaaac
    13021 ctttagccta tacaactgga ttttcctctc tcaaaagtat attcttttgc aggcgaactt
    13081 cctcaaaatc agtcgtgtgc aacttcagta gaatattcat aggctcggat aatctgagcg
    13141 acaactggat ggcgaaccac atccttggct gaaaaatgaa caaagtcaat ctgatggatg
    13201 ttcttgagtt tatcttgagc atcaatcaaa ccggacttga cattacgtgg caggtcaatc
    13261 tgactgatat ctccattgac aatcatctta gaatgaaagc ctaaacgcgt caagaacatc
    13321 ttcatctgca tgatggtcgt gttttgcgcc tcatcgagaa tgacaaaggc atcatccaag
    13381 gtccggccac gcatataggc aaggggcgca atttcgataa tttcacgctc catgagacga
    13441 gtcgtttggt ctttcccaag aatttgatac aaggcatcgt aaacaggacg aaggtaagga
    13501 tccaccttct ccttaagatc acccggaaga aatccaagac tctctcccgc ttccaccgct
    13561 ggacgagtta ggataattcg cttgacttgc ccacgtttaa gggcagtcac tgccaaggtc
    13621 actgcaagga aggtcttccc tgtacctgct ggcccaattc caaaggtcac atcatgctgt
    13681 ttgacactgt ccacataaag tttttgacct aaggttttga cgcggatagg cttcccagta
    13741 ttatccttga tgatttcttc ttcgtaaagg gcgacaaact tgtcaatttc atcatttttg
    13801 accatactaa tagccgtcac tacatctggc gtaccaacgg tcatcccacg atttaccaag
    13861 gccatgagag cttgaataac ctgacgggct tcctcgcaag cagactcttc tcccaaaacc
    13921 tggacaatct ccgtacgagc atgaatcaca acatcaagct cttcttccat caaacgaaga
    13981 tggcgttcat tggaaccaaa aagatgaaac aggtcatctg gatgactcag ttgaatgtct
    14041 attgaatgtt ccttcaaata aagaacctct ctaatccttt tatttctttt tattatagca
    14101 gagggatgga gaaattacta gcccaaaccc aatgaataaa tgctagtgtt ctagatattc
    14161 ctgccaaatg ctgtcaaaat ctcctaggtt aaaagagaaa ctggcatgct cctccaaaaa
    14221 gcgactgacc tcatcaaaat catctgtatg ttttggaaaa gctgcctctt caaaagcgag
    14281 gtctgccaaa attgctttgg gattgttact tttaggattg cgctcggtca tgagccaagt
    14341 gtaaaatgat tttctcataa gcctccctaa atcaactctg taccaaactg gtcctgcttg
    14401 attttaccag ccttcataag accacctaaa gctttcttga actgaccttt agaaatgcca
    14461 aaggttgcct tgatgtcgtc tggagatgac ttgtcattta aggtcatgaa accgccattg
    14521 ctttccaaat aagtcaaaat catctgagca tcgttttcca acatttcaaa ggagcgtggt
    14581 ttgagggaga ggttcaaagt gcggtccact tcacggaaac caataacgcg cgcatctaat
    14641 acttgcccca aacgtggctc tgcgtaacgc tcgctaggat gaataaaacc aagcatgtta
    14701 ttttctggta ggtaaacaaa agttcctgat agcttgagac ggtaaacaat ggctggccag
    14761 ttttggttct gcatgttgtt gtaggcagga cgagcaagac gttggaagtc ttcttgataa
    14821 gccaagagac cccagatacg gtctttctta tccacttcaa gacggatgta gagttggtcg
    14881 cccttcttag gccagagttc cttgagctca gggagaatat cgagtgacac aacgatttcc
    14941 ttgtcaggaa ggcctgtatc cacaaagaca cccaagtcct tacgaacctc tgtgacacgt
    15001 ccccaaccaa attggtcctg agtggcagtc acttctaagc ttgtcaggcg gagtttttgc
    15061 ttcatatccg tgtatgcaaa acctttgacc gtatccccta ctgtatgttg gccttcttcc
    15121 ttagcaagag cataggtttg accatccttt tgcacaaagt aaaaacggtc gttttcatcg
    15181 atgatcagtc caacgataaa acttgcaaga tttgtattca tatttccttc tttcgaataa
    15241 aactcagcca gcaatgccaa ctgagttttt ctgtttattt ttagacttcc aaaagttctt
    15301 tctctttgtt ggcagtcata tcgtcgatgt gtttaacagc atcgtctgtt actttttgaa
    15361 tgtctttttc aagagtcttc aattcgtctt cagtgatttc ttttgctttt tcttgtttct
    15421 tagcttcgtc catagcatcg cgacggatat tgcggacagc cactttagca ttttcgccga
    15481 ccttcttcac ttctttagca aggtcacgac gagtctcttc tgtaagagct gggacaacca
    15541 agcgaatcac agaaccgtca ttagctggtg tgataccaag atcagaagcg ttcaaggcac
    15601 gttcgatgtc tttcaatgaa gacttgtcaa atggtgttac caacaaaaca cgcgcttctg
    15661 gaatcgtaat tgaagcgatt tggttaagag gagtttcaac tccatagtat tctacatgta
    15721 tacggtcaag caagcttgca ttggcacgac cagcacggat accaccaaat tcacgagcaa
    15781 gtgattggtg agactgggtc attctctctt tagctttttc aataattgcg ttagccatat
    15841 tctttcttat tccttttctt cgatattatt tgaaactgtt gttccgatat tttcaccaaa
    15901 tacgacacgt ttgatgttgc ctgattggtt catgttgaag acaaccaagt caatgtcgtt
    15961 gtccattgag agggttgaag ctgttgagtc catgatacga agacctttat tgataacgtc
    16021 acggtgggtc aattcttcaa acttaacagc tgtcttatct ttcttaggat cggcattgta
    16081 aacaccatcg acaccatttt tagccatgag gatggcatcc gcttcgattt cagctgcacg
    16141 aagggccgct gttgtatctg tcgagaagta tggtgaacca attccagcac caaagataac
    16201 gatacggcct ttttcaaggt gacgaagggc acgtccacgg acataaggct ctgccacttg
    16261 ttgcatagca atagctgttt gtacacgcgt atcaacccca acttgttgca atgaatctgc
    16321 catcacaaga gcattcataa cagtcccaag cattccagtg taatctgcct gaacacggtc
    16381 catacctgct tctgctgcag gttctccacg ccagagattt cctccaccaa taacaagggc
    16441 aatttcgata cctaagctat gaacttcttg aatctctttt gcgattgttt gaactgtttg
    16501 gatatcaatc cctacgccac gttcaccggc aagggcttca cctgataact tgattaaaat
    16561 acgtttatac ttgggattcg ccattttcac tctccttctt tcatcctacc tattttatca
    16621 caatttctaa gatttttata gtatcatgaa caattctttc aaaaaaatta gacagtcaaa
    16681 aattcctcta agtcggcaag ggcacgctct gcaatttttt cataacgagc cttcttatca
    16741 cggatacgct cgccttccaa ctccttgatg atcccaaaat tgacattcat tggttggaaa
    16801 tgtttgctgt cggcatgggt aatgtaatga gctaagcttc caatcgctgt cgtctcgggg
    16861 aaaataacct cgctttcttc cttgaagaga cgagctgcgt taattcccgc aactaagccc
    16921 gaagccgccg actcaacata gccttccacc cccgtcatct gaccagcaaa gaagagattt
    16981 ggttgtttct tggaacggta agtctgctca agaagatttg gtgaatccat gtaagaattg
    17041 cgatgcatga caccataacg gacaaactcc gcattttcaa gacccggaat catttggaag
    17101 acacgctttt gttctcccca tttgaggtgg gtctggaaac caacaatatt gtataggcta
    17161 ccagctgcat tatcctgacg aagttgcaca accgcataag gtgttttaaa ttctccatca
    17221 cgaggtcctg tgtagtcgtc cggatactca agaccgactg gcttcatagg gccataaagc
    17281 atagttttaa tgccacgttt ggccataact tcgattggca tacatccttc aaagtacttt
    17341 tctttttcaa aagaattgag cggtgcttct tccgcattga ccaaggcttc atggaaatcc
    17401 ataaactctt gcttggtcat tggagcattg agataggctg cttctccctt atcataacga
    17461 gatttgagat agaccttact catatcgata gtgttgacat cgataatagg cgctgctgca
    17521 tcgtagaaat agaagccatc gccattatta agggcatgaa tcttttcagc cagggcatcg
    17581 ctagtcaagg gaccagtcgc cacaactgta ataacatctg ttggcaattc tgtaatttca
    17641 tcacgcacca cttcaatcaa ggggtggttg accacttttt cggtcaccat ttgagagaaa
    17701 ccatcacgat ccaccgcaag ggctccaccg gcaggaacac gtgtagcctc agcagattcc
    17761 aagataacag aacccaagcg acgcatttct tccttgagaa gaccaactgc atttgtcaaa
    17821 gcatccccac gcaaagaatt ggaacaaacc aactcagcaa aattgtctgt tttatgctgg
    17881 ggtgtagact tgacaccacg catttcatat agtttaactg gaataccacg ctctgcgatt
    17941 tggtaagctg cttcagaacc tgccaaacca gcaccgataa cattgatata agattgagac
    18001 acgacactaa tacctctttg ggagtgtgaa gttaagattc acattgaaaa agccaatcag
    18061 acttacaagc tttcgagttt cttggctcag gctgaaaaag tccattggac ttacttcgct
    18121 ctcgaatttc ttggctca
//
LOCUS       DAVBNZ010000043        18101 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000043 DAVBNZ010000000
VERSION     DAVBNZ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.043"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            3..308
                     /locus_tag="VQ860_001537"
     CDS             3..308
                     /locus_tag="VQ860_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3119944.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            356..1831
                     /locus_tag="VQ860_001538"
     CDS             356..1831
                     /locus_tag="VQ860_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET3119945.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1854..1931
                     /locus_tag="VQ860_001539"
                     /pseudo
     CDS             1854..1931
                     /locus_tag="VQ860_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2091..8792
                     /locus_tag="VQ860_001540"
     CDS             2091..8792
                     /locus_tag="VQ860_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET3119946.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKLEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIANTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLVTVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLVTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVDLTIQANTEKKIAQSIRP
                     VNVVTDLHQEPTLPSTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARARVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEITVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKDIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9040..9896)
                     /locus_tag="VQ860_001541"
                     /pseudo
     CDS             complement(9040..9896)
                     /locus_tag="VQ860_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10107..10466)
                     /locus_tag="VQ860_001542"
     CDS             complement(10107..10466)
                     /locus_tag="VQ860_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET3119947.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLTLSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            10558..11514
                     /locus_tag="VQ860_001543"
                     /pseudo
     CDS             10558..11514
                     /locus_tag="VQ860_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11498..12055
                     /locus_tag="VQ860_001544"
     CDS             11498..12055
                     /locus_tag="VQ860_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3119948.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12048..12302
                     /locus_tag="VQ860_001545"
     CDS             12048..12302
                     /locus_tag="VQ860_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3119949.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12314..14368
                     /locus_tag="VQ860_001546"
     CDS             12314..14368
                     /locus_tag="VQ860_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET3119950.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEKSKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14547..15407
                     /locus_tag="VQ860_001547"
     CDS             14547..15407
                     /locus_tag="VQ860_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET3119951.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ860_001548"
     CDS             15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ860_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3119952.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16356..16922
                     /locus_tag="VQ860_001549"
     CDS             16356..16922
                     /locus_tag="VQ860_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET3119953.1"
                     /translation="MKKWQTCVLGAGSLLWLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16933..18045
                     /gene="msrB"
                     /locus_tag="VQ860_001550"
     CDS             16933..18045
                     /gene="msrB"
                     /locus_tag="VQ860_001550"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3119954.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         5445 a         3449 c         3978 g         5229 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattccgta
      241 tcccagcaat gagcgctcca gtatttgaca atattgaagc agctattaaa gaacacggat
      301 taagctaatt ctaatttgtt aacattcata taacataaaa aagggaggaa ctgttatgga
      361 tgcaatcttt gacctaatcg gaaaggtttt caatcccatc ttagaaatgg gtggacctgt
      421 catcatgttg atcattttga cagtattggc tttacttttt ggagtgaaat tctccaaagc
      481 gcttgaaggt ggtatcaaac ttgccatcgc tcttacaggt atcggtgcta tcatcggtat
      541 gctaaatggt gctttctcag catcacttgc aaaattcgtt gaaaacactg gtatccaatt
      601 gagtattaca gacgttggtt gggcaccact cgcaacaatc acttggggtt ctgcttggac
      661 actatacttc ttgctcatca tgttgattgt caacgtagtg atgcttgcta tgaagaaaac
      721 cgatacactt gatgtcgata tatttgatat ctggcacttg tctatcacag gtctcttgat
      781 taaatggtat gctgataaca atggtgtgag tcaaggggtt tcactcttta ttgctacagc
      841 agctatcgtc cttgtcggtg tgttgaaaat tatcaactct gacttgatga aacctacatt
      901 tgatgacctt cttaacgccc caagttcatc accaatgaca tcaactcaca tgaactacat
      961 gatgaaccca gttatcatgg ttttggataa gatttttgaa aaattcttcc caggccttga
     1021 taaatatgac tttgatgctg ctaaattgaa caagaaaatc ggtttctggg gatctaaatt
     1081 cttcatcggt ttcatccttg gtatcgttat cggtattatg ggaactccac atccaattgc
     1141 aggtgttgca gatgcagata aatggcgtct tgttatcaaa ggatggttgt ctcttggttt
     1201 gactgccggt gtatctttgg aactcttctc acttatcggt tcatggttca tcgcagccgt
     1261 agaaccacta tcacaaggta ttacaaacgt tgctactaaa cgtcttcaag gacgtaaatt
     1321 caatatcggt cttgactggc cattcatcgc tggtcgtgct gaaatctggg cttgtgccaa
     1381 cgtacttgca ccaatcatgt tgattgaagc agtgcttctt tcaaaagttg gaaatggtat
     1441 cttgccactt gcaggtatca tcgctatggg tgttactcca gctctcttgg ttgtaactcg
     1501 tggtaaattg ctccgtatga ttatcttcgg aacactcttg ttgccactct tccttctttc
     1561 aggtaccctt attgcaccat ttgcaacaga acttgctaaa ggtgtaggtg ccttcccaga
     1621 aggtgtgagc caaactcaat tgattactca ctctactctt gaaggaccaa tcgaaaaact
     1681 tcttggttgg acaattggta acactacaac tggtgatatc aaagcaatcc ttggtgcagt
     1741 agccttcctt gtattctata tcggtatctt tgcttggtac agaaaacaaa tgatcaaacg
     1801 taacgaagag tacgcagcaa aagcaaaata atgcgctcct ataaaatata aactcaatga
     1861 aaatcaaaga gcaaactagg aaactagcca caggttgctc aaaacacagt tttgaggttg
     1921 tagatgaaac tgacgaagtc agtaatcata tctacggcaa ggcgacgctg acgaagtttg
     1981 aattggattt tcgcagagtg taaattgttg aaactaggtt gtcataccat gtataccact
     2041 tgggctttgg tagtagctaa ctgcactaaa tataatataa ggagggtttt atggggaaag
     2101 gccattggaa tcggaaaaga gtttatagca ttcgtaagtt tgctgtggga gcttgctcag
     2161 taatgattgg gacttgtgca gttctattag gaggaaatat agctggagaa tctgtagttt
     2221 atgcggatga aacacttatt actcatactg ctgagaaacc taaagaggaa aaaatgatag
     2281 tagaagaaaa ggctgataaa gctttggaaa ctaaaaatgt agttgaaagg acagaacaaa
     2341 gtgaacctag ttcaactgag gctattgcat ctgagaagaa agaagatgaa gccgtaactc
     2401 caaaagagga aaaagtgtct gctaaactgg aagaaaaagc tccaaggata gaatcacaag
     2461 cttcaagtca agaaaaaccg ctcaaggaag atgctaaagc tgtaacaaat gaagaaatga
     2521 atcaaatgat tgaagacagg aaagtggatt ttaatcaaaa ttggtacttt aaactcaatg
     2581 caaattctaa ggaagccatt aaacctgatg tagacgtatc tacgtggaaa aaattagatt
     2641 taccgtatga ctggagtatc tttaacgatt tcgatcatga atctcctgca caaaatgaag
     2701 gtggacagct caacggtggg gaagcttggt atcgcaagac tttcaaacta gatgaaaaag
     2761 acctcaagaa aaatgttcgc cttacttttg atggcgtcta catggattct caagtttatg
     2821 tcaatggtca gttagtgggg cattatccaa atggttataa ccagttctca tatgatatca
     2881 ccaaatacct tcacaaagat ggtcgtgaga atgtgattgc tgtccatgca gtcaacaaac
     2941 agccaagtag ccgttggtat tcaggaagtg gtatctatcg tgatgtgact ttacaagtga
     3001 cagataaggt gcatgttgag aaaaatggga caactatttt aacaccaaaa cttgaagaac
     3061 aacaacatgg caaggttgaa actcatgtga ccagcaaaat cgccaatacg gacgacaaag
     3121 accatgaact tgtagccgaa tatcaaatcg ttgaacgagg tggtcatgct gtaacaggct
     3181 tagttcgtac agcgagtcgt accttaaaag cacatgaatc aacaagccta gatgcgattt
     3241 tagaagttga aagaccaaaa ctctggaccg ttttaaatga caaacctgcc ttgtacgaat
     3301 tgattacgcg tgtttaccgt gacggtcaat tggttgatgc taagaaggat ttgtttggtt
     3361 accgttacta tcactggact ccaaatgaag gtttctcttt gaatggtgaa cgtattaaat
     3421 tccatggagt atccttgcac cacgaccatg gggcgcttgg agcagaagaa aactataaag
     3481 cagaatatcg ccgtctcaaa caaatgaagg agatgggagt taactccatc cgtacaaccc
     3541 acaaccctgc tagtgagcaa accttgcaaa tcgcagcaga actaggttta ctcgttcagg
     3601 aagaggcttt tgatacttgg tatggtggca agaaacctta tgactatgga cgtttctttg
     3661 aaaaagatgc cactcaccca gaagctcgaa aaggtgaaaa atggtctgat tttgacctac
     3721 gtaccatggt cgaaagaggc aaaaacaacc ctgctatctt catgtggtca attggtaatg
     3781 aaataggtga agctaatggt gatgcccact ctttagtaac tgttaaacgt ttggtcaagg
     3841 ttatcaagga tgttgataag actcgctatg ttaccatggg agcagataaa ttccgtttcg
     3901 gtaatggtag cggagggcat gagaaaattg ctgatgaact cgatgctgtt ggatttaact
     3961 attctgaaga taattacaaa gcccttagag ctaagcatcc aaaatggttg atttatggat
     4021 cagaaacatc ttcagctacc cgtacacgtg gaagttacta tcgccctgaa cgtgaattga
     4081 aacatagcaa tggacctgag cgtaattatg aacagtctga ctatgggaat gatcgtgtgg
     4141 gttgggggaa aacagcaacc gcttcatgga cttttgaccg tgacaacgct ggctatgctg
     4201 gacagtttat ctggacaggt acggactata ttggtgaacc tacaccatgg cacaaccaaa
     4261 atcaaactcc tgttaagagc tcttactttg gtatcgtaga tacagccggc attccaaaac
     4321 atgacttcta tctctaccaa agccaatggg tttctgttaa gaagaaaccg atggtacacc
     4381 ttcttcctca ctggaactgg gaaaacaaag aattagcatc caaagtagct gactcagaag
     4441 gtaagattcc agttcgtgct tattcgaatg cttctagtgt agaattgttc ttgaatggaa
     4501 aatctcttgg tcttaagact ttcaataaaa aacaaaccag cgatgggcgg acttaccaag
     4561 aaggtgcaaa tgctaatgaa ctttatcttg aatggaaagt tgcctatcaa ccaggtacct
     4621 tggaagcaat tgctcgtgat gaatctggca aggaaattgc tcgagataag attacgactg
     4681 ctggtaagcc agcggcagtt cgtcttatta aggaagacca tgcgattgca gcagatggaa
     4741 aagacttgac ttacatctac tatgaaattg ttgacagcca ggggaatgtg gttccaactg
     4801 ctaataatct ggttcgcttc caattgcatg gtcaaggtca actggtcggt gtagataacg
     4861 gagaacaagc cagccgtgaa cgctataagg cgcaagcaga tggttcttgg attcgtaaag
     4921 catttaatgg taaaggtgtt gccattgtca aatcaactga acaagcaggg aaattcaccc
     4981 ttactgccca ctctgatctc ttgaaatcga accaagtcac tgtctttact ggtaagaaag
     5041 aaggacaaga gaagactgtt ttggtgacag aagtgccaaa agtacagacc attattggag
     5101 aggcacctga aatgcctacc actgttccgt ttgtatacag tgatggtagc cgtgcagaac
     5161 gtcctgtaac ctggtcttca gtagatgtga gcaagcctgg tattgtaacg gtgaaaggta
     5221 tggctgacgg acgagaagta gaagctcgtg tagaagtgat tgctcttaaa tcagagctac
     5281 cagttgtgaa acgtattgct ccaaatactg acttgaattc tgtagacaaa tctgtttcct
     5341 atgttttgac tgatggaagt gtacaagagt atgaagtgga caagtgggag attgccgaag
     5401 aagataaagc taagttagca attccaggtt ctcgtattca agcgaccggt tatttagaag
     5461 gtcaaccaat tcatgcaacc cttgtggtag aagaaggcaa tcctgcggca cctgcagtac
     5521 caactgtaac ggttggtggt gaagctgtca caggtcttac tagtcaaaaa ccaatgcaat
     5581 accgcactct tgcttatgga gctaagttgc cagaagtcac agcaagtgct aaaaatgcag
     5641 ctgttacagt tcttcaagca agcgcagcaa acggcatgcg tgcgagcatc tttattcagc
     5701 ctaaagatgg tggccctctt caaacctatg caattcaatt ccttgaagaa gcgccaaaaa
     5761 ttgctcactt gagcttgcaa gtggaaaaag ctgacagtct caaagaagac caaactgtca
     5821 aattgtcggt tcgagctcac tatcaagatg gaacgcaagc tgtattacca gctgataaag
     5881 taaccttctc tacaagtggt gaaggggaag tcgcaattcg taaaggaatg cttgagttac
     5941 ataagccagg agcagtcact ctcaaagcgg aatatgaggg agctaaaggc caagttgatc
     6001 tcactatcca ggccaatact gagaagaaga ttgcgcaatc tatccgtcca gtaaatgtag
     6061 tgacagattt acaccaagaa cctactcttc cgtcaacagt aacggttgag tatgacaaag
     6121 gtttccctaa agctcacaaa gtcacttggc aagctattcc gaaagaaaaa ctagactcct
     6181 atcaaacctt tgaagtacta ggtaaagttg aaggaattga ccttgaagcg cgtgcaagag
     6241 tctctgtaga aggtatcgtt tcagttgaag aagtcagtgt gacaactcca atcgcagaag
     6301 caccacaatt accagaaagc gttcggacat atgattcaaa tggtcacgtt tcatcagcta
     6361 aggttgcatg ggatgcgatt cgtatagagc aatacgctaa ggaaggtgtc tttacagtta
     6421 atggtcgctt agaaggtact caattaacaa ctaaacttca tgttcgcgta tctgctcaaa
     6481 ctgagcaagg tgcaaatatt tctgaccaat ggaccggttc agaattgcca cttgcctttg
     6541 cttcagactc aaatccaagc gacccagttt caaatgttaa tgacaagctc atttcctaca
     6601 ataaccaacc agccaatcgt tggacaaact ggaatcgtag taatccagaa gcttcagtcg
     6661 gtgttctgtt tggagattca ggtatcttga gcaaacgctc cgttgataat ctaagtgtcg
     6721 gattccacga agaccatgga gttggtgcac cgaagtctta tgtgattgag tattatgttg
     6781 gtaagactgt cccaacagct cctaaaaacc ctagttttgt tggtaatgag gaccatgtct
     6841 ttaatgattc tgccaactgg aaaccagtta ctaatctaaa agcccctgct caactcaagg
     6901 ctggagaaat gaaccacttt agctttgata aagttgaaac ctatgctgtt cgtattcgca
     6961 tggttaaagc agataacaag cgtggaacgt ctatcacaga ggtacaaatc tttgcgaaac
     7021 aagttgcggc agccaaacaa ggacaaacaa gaatccaagt tgacggcaaa gacttagcaa
     7081 acttcaaccc tgatttgaca gactactacc ttgagtctgt agatggaaaa gttacggcgg
     7141 tcacagcaag tgttagcaac aatggtctcg ctaccgtcgt tccaagcgtt cgtgaaggtg
     7201 agccagttcg tgtcatcgcg aaagctgaaa atggcgacat cttaggagaa taccgtctgc
     7261 acttcactaa ggataagagc ttactttctc ataaaccagt tgctgcggtt aaacaagctc
     7321 gcttgctaca agtaggtcaa gcacttgaat tgccgactaa ggttccagtt tacttcacag
     7381 gtaaagacgg ctacgaaaca aaagacctga cagttgaatg ggaagaagtt ccagcggaaa
     7441 atctgacaaa agcaggtcaa tttactgttc gaggccgtgt ccttggtagt aaccttgttg
     7501 ctgagatcac tgtacgagtg acagacaaac ttggtgagac tctttcagat aaccctaact
     7561 atgatgaaaa cagtaaccag gcctttgctt cagcaaccaa tgatattgac aaaaactctc
     7621 atgaccgcgt tgactatctc aatgacggag atcattcaga aaatcgtcgt tggacaaact
     7681 ggtcaccaac accatcttct aatccagaag tatcagcggg tgtgattttc cgtgaaaatg
     7741 gtaagattgt agaacggact gttgcacaag gaaaagttca gttctttgca gatagtggta
     7801 cggatgcacc atctaaactc gttttagaac gctatgtcgg tccagagttt gaagtgccaa
     7861 cctactattc aaactaccaa gcctacgacg cagaccatcc attcaacaat ccagaaaatt
     7921 gggaagctgt tccttatcgt gcggataaag acattgcagc tggtgatgaa atcaacgtaa
     7981 catttaaaga tatcaaagcc aaagctatga gatggcgtat ggagcgtaaa gcagataaga
     8041 gcggtgttgc gatgattgag atgaccttcc ttgcaccaag tgaattgcct caagaaagca
     8101 ctcaatcaaa gattcttgta gatggaaaag aacttgctga tttcgctgaa aatcgtcaag
     8161 actatcaaat tacctataaa ggtcaacggc caaaagtctc agttgaagaa aacaatcaag
     8221 tagcttcaac tgtggtagat agtggagaag atagccttcc agtacttgtt cgcctcgttt
     8281 cagaaagtgg aaaacaagtc aaggaatacc gtatccactt gactaaggaa aaaccagttt
     8341 ctgagaagac agttgctgct gtacaagaag atcttccaaa actcgaattt gttgaaaaag
     8401 atttggccta caagacagtt gagaaaaaag attcaacact gtatctaggt gaaactcgtg
     8461 tagaacaaga aggaaaaact ggtaaagaac gtatctttac agcgattaat cctgatggaa
     8521 gtaaggaaga aaaactccgt gaagtggtag aagctccgac agaccgcatc gtcttggttg
     8581 gaaccaaacc agtagctcaa gaagctaaaa aaccacaagt gtcagaaaaa gcagatacaa
     8641 aaccaattga ttcaagtgaa gctagtcaaa ctaataaagc ccagttacca aatacaggta
     8701 gtgcgtcaag ccaagcagca gtagcagcag gtttagctct tctaggtttg agtgcaggat
     8761 tagtagttac taaaggtaaa aaagaagact agaaattttg ataccttctt tatcattaaa
     8821 gaccaaagaa aaactcttgt cctaaataga agataaagag tctggaacaa aatagttctc
     8881 aaccacaaaa aagctagata tttccaattg cggaactcta gctttttaat tttgagtcgt
     8941 tctctgattg tatagtagat tgaaactaga gtagtacact tctacttcta aaacattgtt
     9001 agaaatcgat ttgactgtcc ttatcgattt gtcctgttct tatttgattt cactatgttt
     9061 taggaggtta ttggccataa gtaccaatcc catgtcaatt ctcacttgac gcttgcctct
     9121 cagattacat ctcttgtaac ccaaacaagc ctttatctgc ccaaagacag gttccacatc
     9181 aatcttgcgt tgagcgaaaa tctgtctatc ttggggagat aaaagcgcct gacattcttt
     9241 agctttcaag ttttgatagc gttcgttcat atacagtccc ttttgagggg ctgattcagg
     9301 ttcatcagcg tagtaaacct tgatttcctg ttgaaagtct gtctgtgttt tctggtactt
     9361 gatatggtga aaacgatagc accagccatc aggatgtatg tagctatcct ccttgtcatt
     9421 atagtgccaa ttcgctaagt ttttagctga ctgtttatac cctctctttt gtttcttatc
     9481 aaacatggca tatttaatca gaaggggagt gatttcttct tgaaaataga cttgtatctg
     9541 ttcttgaagt ttggcggaga atttctctgt ctttttcttc cacacaaaac tatacttgtt
     9601 ggcattggct tcaatcttag ttccgtcaat aaacaaacaa tctaaggtca ctaactcttc
     9661 catttttcaa tttttcgacc agagaaaatc ccttgtgaat aggcaaatag aagagtagat
     9721 acaagcattt taaggtgata agacgggcga tcaaaggcat gatagaaggc gtggaaatga
     9781 caatcctcca aggtattcac cactttttca atagtaaaaa cgagatggtc ttgtggcaag
     9841 aaggaactga tttctagtgg taaagttgtt tgatttgtgt tatagtgaat atgcatggga
     9901 tagcctttct aaatggttta ttgtgcaatt ctattttacc aagactatcg caaccatgca
     9961 aaaaagcaac ggcaaatccg ttgctttttt tggagataag agactattgt cccagactct
    10021 tttctttgta taaaattgta tagtgttatt gtctatacta ttttgtagag aaagcaaaaa
    10081 tccctagaaa atgcttaggg attcgactat ttcattaaga acaattcaac aatcatttct
    10141 acatacatga taagggttaa taagaatcct gcacgccaga agaatttgat gaatttagga
    10201 tagtaaaagc tgcgtttttt caaaaggaag aaaaagacga gaataatggc taggatcgag
    10261 agggttagcc ccagtctagg gaggaaatta tgggtaaagg ttttagctgt aatcaagtaa
    10321 tactcaaata ccaagactgg aaaagccaaa tccgcaaagt ttcgtcctag tttttttaat
    10381 ctaaaaagtt tggttaggat aatgcagatg actaaggtca gtatcaataa taaaatagat
    10441 gctaatttca ttaaaatcat acccatattg tatcataaaa aaaggctaat ggaaacgaga
    10501 aacagaggaa tttataagaa agtcaggctt ttgagattgt gggtgatttt tgttataatg
    10561 aaagttataa aatcttataa taccttgaat gattattatc gaaaactctt tggagaaaag
    10621 acttttaaag tccctattga tgcgggattt gactgtccca atcgtgatgg aactgtggct
    10681 catggaggct gtactttttg tacggtttca ggttctggag atgctattgt agccccagat
    10741 gcgcctatcc gtgagtaatt ttataaggaa attgacttta tgcaccgtaa gtggccggat
    10801 gttcagaagt atctggttta ttttcaaaat tttaccaaca ctcatgaaaa ggtggaagtt
    10861 attcgagagc gttatgaaca ggctatcaat gagccaggtg tggtaggaat caatattgga
    10921 acgcgcccag actgtttacc agacgaaacc atcgaatatt tggctgagtt atcggagtgc
    10981 atgcatgtga cgtttgaatt gggcttgcaa actacttatg aagcaacctc tgacctgatt
    11041 aaccgtgcgc attcttatga attgtaggtg gaaacggtca agcgtttgag aaagtatcca
    11101 aaaattgaga ttgtttccca tttgatcaat ggtttgcctg gtgaaaccca tgagatgatg
    11161 gttgaaaatg tccgccgttg tgtcacggat aacgatattc aagggattaa actgcatttg
    11221 ctccatctta tgacaaatac tcgtatgcaa cgagattacc atgaggggcg tttacaattg
    11281 atgagtcagg acgaatatgt cagggtcatc tgtgaccaac tggaaattat tcccaaacat
    11341 atcgtcatcc atcgaattac aggagatgcg cctagggata tgctgcttgg gcctatgtgg
    11401 agcctcaata aatgggaagc tctcaacagc attgagatgg agatgcgacg tcgtggaagt
    11461 gttcaaggat gcaaggctgt aaaacaggag tttgaaaatg aaaagaccac ttgagatggc
    11521 acatgatttt ttggctgagg tcgtgacaaa agaggatgtc gtagtggatg cgactatggg
    11581 aaatggtcat gacacgcttt ttttagccaa gctagccaag caagtctatg cctttgatat
    11641 tcagaagcaa gccttggaaa agacccaaga gcgtttgcat caggctgact tgacaaatgc
    11701 ccagttaatc ttgcaaggcc atgagacact ggaccagttt gtgataaaag ctaaggcagg
    11761 gatttttaat ctgggctatt tgccgtcagc tgataagtct gtcatcaccc gaccgcagac
    11821 aacgattgag gcattagaaa agctatgtgg cttacttgtc aaaggtggac gaattgctat
    11881 tatgatttac tatggtcatg aaggaggcga tctcgagaga gatgctgtct tggattttgt
    11941 gatccagttg aaccaacaag agtacacagc tgccatttac cgaactttaa accaagtcaa
    12001 caacccgccg tttttagtga tgattgaaaa attagagaga tacagacatg gataaacaat
    12061 acttacacga aaagctggat gccatgcgcc agaattttgt tgaatcaacc caccacgaac
    12121 gagcggtggg cgtgctagac caagcgcata tgagcaaaaa aatgcttaaa atcaagaaaa
    12181 aattagttgc tcttgaaatg gaacggtgcc agagaaaaat tgagcacaaa gactgttcca
    12241 agattgacca aaaaatcaaa gagcagaagg agatatttga atcctgttgt aaaaaagatt
    12301 aaggaggacg tgcgtggaat tactgattta cctcatccta tttttactgg ttttgattgt
    12361 ctcaagtaca accaataagc tcctgccctt tttgcctctc cctttggtgc aaattctttt
    12421 gggaattgtg attggtctct ttttacccaa tactgacttt caccttaata cggagttgtt
    12481 tttggcactg gttatcggac ccttgctttt ccgagaggct gaagaagcag atgttacggc
    12541 tattttaaaa cactggcgaa tcattgttta tctcatattt ccagtgattt ttatctcgac
    12601 cctgagtttg ggtggcttgg cccatcttct ttggttcagc cttcccttgg cagcttgctt
    12661 ggctgttggg gcagcccttg gtcctacgga cttggtggcc tttgcctctc tttcggagcg
    12721 ttttagcttt cctaagcgcg tgtccaatat tcttaagggc gaaggactct tgaatgatgc
    12781 ttctggtttg gtggcttttc aggtagcttt gacagcttgg acaactggag ctttttctct
    12841 ggggcaagct agcagttcgc tcatcttttc aatcctaggc ggttttttaa ttggattttt
    12901 aacagccatg accaaccgct tcctccatac cttcttgcta agtgtgcgcg caacggatat
    12961 tgccagtgaa cttttattag aattgagttt gcctctagtg accttctttc tggcagaaga
    13021 agtccatgtt tcaggtatta ttgccgtcgt agttgctgga attttaaagg caagtcgctt
    13081 caagaaaatc acgctcctcg aagcccaagt ggatacggtg accgagacgg tctggcatac
    13141 agtgaccttt atgctcaacg gttctgtctt tgtgatttta gggatggagt tggaaatgat
    13201 agcagaacct atcttgacca atccaatcta taatcctcta cttttattgc tatctctcat
    13261 cgcccttacc tttgtcctct ttgtcattcg ttttattatg atctatggct attatgccta
    13321 tagaacccga cgcctcaaga aaaagctaaa taagtatatg aaggacatgt ttctcttgac
    13381 cttttcaggt gttaagggaa cggtgtcgat tgctacgatt ctcttgatac caagtaatct
    13441 agaacaggag tatcctcttt tgcttttcct tgttgcaggt gtgacgcttg tcagcttttt
    13501 aacaggtctc ttggtcttgc ctcatctttc tgatgaagag gaaaaaagca aggattatct
    13561 catgcatatc gccattttga atgaagtaac gctagagttg gaaaaagagt tggaagacac
    13621 cagaaataaa cttcccctct atgcggctat tgacaattat catggacgta ttgaaaatct
    13681 cattttaagc caagaaaacc aggatgatca agaagactgg gctgctttga aactcttgat
    13741 tcttagtatt gaaagtgatg gtttggaaca ggcctatgaa gaggggaaca ttagcaatcg
    13801 tgcttaccga gtttaccaac gttatctgaa aaatatagaa caaggaatca atcgtaaact
    13861 tgcctcaaga ctgacctatt atttccttgt ttccttgagg attttacgtt ttctccttca
    13921 tgaagttttt actcttggaa agaccttccg tagctggaag gacaaggagc aaagccgtct
    13981 ccgtgctctt gattatgacc aaattgcaga gctctatctt gccaatacgg agatgattat
    14041 tgaaagtttg gaaaacctga agggagtcta cagacgctct ttgattagtt ttatgcagga
    14101 gtctcgtctt cgagaaacag ctattatcag cagtggtgcc tttgtcgaac gggttatcaa
    14161 tcgtgtcaaa cccaacaata tcgatgaaat gctgagaggc tattatctgg agcgcaagtt
    14221 gattttcgaa tacgaagaaa aacgattaat tacaactaag tatgccaaga aattacgaca
    14281 aaatgtaaat aacttagaga actattcctt gaaggaagct gccaataccc tgccgtatga
    14341 tatggtggaa ttggtaagaa gaaattagtt aatactcttc gaaaatctct tcaaaccacg
    14401 tcagcgtcgc cttggattat atatgtgact gacttcgtca gtttcatcta caacctcaaa
    14461 gcagggcttt gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta
    14521 taagattata aatgaaggag tatgacatga aaaagtggtg gaaagagctg atagacaagc
    14581 ctttattaaa agcttttttg cattattatc aagcatcaga tagtgagttg accagtgtcg
    14641 cagtagccta ctattggttg atttcgattt tccccctgct tttggtggtg gtcaatatcc
    14701 tcccctattt tcagattcct gtgggagaat ttctgtgctt tatgaaagac gttctgcccc
    14761 caagcctcta tgaaggtgtg gaaaaaatag ccagagaagt tttgacgcaa ccttcaacag
    14821 gtttattaag tttttctgtt ttatcggcgt tatggagttt ttcaaaatct atgaatttct
    14881 tgcaaaaagc ttttaacaag gcttatggcg tcgaaaagag tcgtggactt atttcccatc
    14941 agatgctaag tctcctagtc agttttggct tgcagctcct ctttgcgttt gccttgtttt
    15001 tgatcttatt tggtcagatg attttggctt tacttgctca ttattggaca aaagatggca
    15061 ttatctatca ggctttacaa gggttggcag gtcctctgat ttacgccctc ctctttgcta
    15121 tcttggtcat gctttattat tttcttccca atatatctaa caggaaaatt agctataccc
    15181 taccaggcag tgcctttgtt ctcttagtga ttttaggttt actaactctg ttctctagtt
    15241 atctcaatta ctatgtccat catttggtgg atgtccgaat tttaggttcc gttcttcttg
    15301 ttgttatgat gttttggttt atcttgattg ctaaaattgt tatcctaggc gcggttatca
    15361 atgccagtat gcagagtttg aaagatccgg tctttaaaaa agactaacta tttatccatt
    15421 ataaaagcgc atagtatcaa gactttatag aaccttgata ctatgcgctt ttgcgctttt
    15481 gtgctttgac agttttttgt atagtttttg tccaagattt ctaaatcatc tgattaaatt
    15541 cctattttcc cctatcattg tccctgtttt ttcgaaaatg gaaggagtat aataaatcta
    15601 tcaataaaat gataggagga actttatggg tcatattttc ttttttctaa gtgtcttttt
    15661 ggcagggatt ctatccttct tttctccttg tatcttacct ttgttaccgg tctatacagg
    15721 agtgttacta gatgataagg atggtgctca ggcttctagc ggcaaatttt caatctcagt
    15781 tactagttta ttacgaactc tggcctttat agcaggaatt tcctttatat ttattttgtt
    15841 gggctatgga gctggttttt taggcgattt gctttatgct tcttggttcc aatatcttac
    15901 tggggcaatt attatccttc ttggtttgca ccaaatggag attctacact ttaaggggct
    15961 ttataaggaa aagaggctac aactgcaagg acaggggcaa aatggtaagg gctatagtca
    16021 ggcattttta ttgggcttga cctttagttt tgcttggacg ccttgcgtgg ggccggttct
    16081 ggggtctgtt ttggccttgg cggcttcagg tggttcagga gcttggcagg gagctggtct
    16141 catgttggtg tatacgctgg gcttggcgct accattcttg cttctagctc tgacctctag
    16201 ttatgttttg aaacatttcc gaaaacttca tccctatctc ggaatcctca aaaaagtggg
    16261 tggttttctc attattgtga tgggactctt ggttctgttt ggaaatgctt caattttaag
    16321 tcaattattt gaataaaatg gaaaggaata tcaatatgaa aaaatggcaa acatgtgttc
    16381 ttggagcagg ttcgctcctt tggttgacgg cttgttcagg caagtccgtg actagtgaac
    16441 accaaacgaa agatgaaatg aagacggagc agacagctag taaaacaagc gcagctaaag
    16501 ggaaagaggt ggctgatttt gaattgatgg gagtagatgg caagacctac cgtttatctg
    16561 attacaaggg caagaaagtc tatctcaaat tctgggcttc ttggtgttcc atctgtctgg
    16621 ctagtcttcc agatacggat gagattgcta aagaagctgg tgatgactat gtggtcttga
    16681 cagtagtgtc accaggacat aagggagagc aatctgaagc ggactttaag aattggtata
    16741 agggattgga ttataaaaat ctcccagtcc tagttgaccc atcaggcaaa cttttggaaa
    16801 cttatggtgt ccgttcttac ccaacccaag cctttataga caaagaaggc aagctggtca
    16861 aaacacatcc aggcttcatg gaaaaagatg caattttgca aactttgaag gaattagcct
    16921 aggaggtgtc ttatgaatga taagttaaaa atcttcttgt tgctaggagt attttttcta
    16981 gccataaccg gtttctatgt tctattgata cgaaatgcag ggcagacaga tgcctcgcaa
    17041 attgaaaagg cggcagttag ccaaggagga aaagcagtga aaaaaacaga aattagtaaa
    17101 gacgcagact tgcacgaaat ttatctagct ggaggttgtt tctggggagt ggaggaatat
    17161 ttctcacgcg ttcccggggt gacggatgcc gtttcaggct atgcaaatgg tagaggagaa
    17221 acaaccaagt acgaattgat taaccaaaca ggtcatgcag aaaccgtcca tgtcacctat
    17281 gatgccaagc aaatttctct caaggaaatc ctgcttcact atttccgcat tatcaatcca
    17341 accagcaaaa ataaacaagg aaatgatgtg gggacccagt accgtactgg tgtttattac
    17401 acagatgaca aggatttgga agtgattaac caagtctttg atgaggtggc taagaaatac
    17461 gatcaacctc tagcagttga aaaggaaaac ttgaagaatt ttgtggtggc tgaggattac
    17521 catcaagact atctcaagaa aaatccaaat ggctactgcc atatcaatgt taatcaggcg
    17581 gcctatcctg tcattgatgc cagcaaatat ccaaaaccaa gtgatgagga attgaaaaag
    17641 accctgtcac ctgaggagta tgcagttacc caggaaaatc aaacagaacg agctttctca
    17701 aaccgttact gggataaatt tgaatccggt atctatgtgg atatagcaac tggggaacct
    17761 ctcttttcat caaaagacaa atttgagtct ggttgtggct ggcctagttt tacccaaccc
    17821 atcagtccag atgttgtcac ctacaaggaa gataagtcct acaatatgac gcgtatggaa
    17881 gtgcggagcc gagtaggaga ttctcacctt gggcatgtct ttacggatgg tccacaggac
    17941 aagggcggct tacgttactg tatcaatagc ctctctatcc gctttattcc caaagaccaa
    18001 atggaagaaa aaggctacgc ttatttacta gattatgttg attaatactc ttcgaaaatc
    18061 tcttcaaacc acgtcagcgt cgccttaccg tatgtagggt t
//
LOCUS       DAVBNZ010000044        17991 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000044 DAVBNZ010000000
VERSION     DAVBNZ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17991
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.044"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            331..1377
                     /gene="pheS"
                     /locus_tag="VQ860_001551"
     CDS             331..1377
                     /gene="pheS"
                     /locus_tag="VQ860_001551"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET3119955.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1377..1886
                     /locus_tag="VQ860_001552"
     CDS             1377..1886
                     /locus_tag="VQ860_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3119956.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1963..4365
                     /locus_tag="VQ860_001553"
     CDS             1963..4365
                     /locus_tag="VQ860_001553"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET3119957.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(4433..5434)
                     /locus_tag="VQ860_001554"
     CDS             complement(4433..5434)
                     /locus_tag="VQ860_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3119958.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5590..6037
                     /locus_tag="VQ860_001555"
                     /pseudo
     CDS             5590..6037
                     /locus_tag="VQ860_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6163..6429
                     /locus_tag="VQ860_001556"
     CDS             6163..6429
                     /locus_tag="VQ860_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3119959.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEL
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKILAVVRLEQGKS"
     gene            6689..8938
                     /gene="metE"
                     /locus_tag="VQ860_001557"
     CDS             6689..8938
                     /gene="metE"
                     /locus_tag="VQ860_001557"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET3119960.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYFFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            9002..9868
                     /gene="metF"
                     /locus_tag="VQ860_001558"
     CDS             9002..9868
                     /gene="metF"
                     /locus_tag="VQ860_001558"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET3119961.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEEHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10427..12640
                     /gene="pnp"
                     /locus_tag="VQ860_001559"
     CDS             10427..12640
                     /gene="pnp"
                     /locus_tag="VQ860_001559"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET3119962.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELITFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            12656..13273
                     /gene="cysE"
                     /locus_tag="VQ860_001560"
     CDS             12656..13273
                     /gene="cysE"
                     /locus_tag="VQ860_001560"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET3119963.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13285..14169
                     /locus_tag="VQ860_001561"
     CDS             13285..14169
                     /locus_tag="VQ860_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3119964.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFEREIASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14251..15594
                     /locus_tag="VQ860_001562"
     CDS             14251..15594
                     /locus_tag="VQ860_001562"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET3119965.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15587..15973
                     /locus_tag="VQ860_001563"
     CDS             15587..15973
                     /locus_tag="VQ860_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET3119966.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            15977..16861
                     /locus_tag="VQ860_001564"
     CDS             15977..16861
                     /locus_tag="VQ860_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET3119967.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTYVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            16998..17432
                     /locus_tag="VQ860_001565"
                     /pseudo
     CDS             16998..17432
                     /locus_tag="VQ860_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17740..17910
                     /locus_tag="VQ860_001566"
                     /pseudo
     CDS             17740..17910
                     /locus_tag="VQ860_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5428 a         3446 c         4088 g         5029 t
ORIGIN      
        1 tcatcttatt tcaatccgct ataaagttag ataagaataa gctaacaagc agaagtaaga
       61 taggtcttgc aagaatggta aaaatctgat aaactaagtg gtaattgaat agaaatctga
      121 aagactagta gcccaaggga agtatatcag ggaggagagc cgtgactgca agctctctat
      181 atgaaagctg ggtgaattca cttgcgcatg gatttagaaa tgaaggtctg acttgtcaga
      241 tgaaaacgga tggtaccgcg tgtcaacgct ccgagtggag tttttggcat gtggttttct
      301 ttttatctac gagagactga tggaggaaat atgtcaacta ttgaagaaca attaaaagcg
      361 cttcgcgaag aaacgctgac tagcttgaag cagattactg ctggaaatga aaaagagatg
      421 caagatttgc gtgtctctgt ccttggtaaa aagggttcgc tcactgaaat cctcaaaggg
      481 atgaaagatg tttctgctga gatgcgtcca atcatcggga aacacgtcaa tgaagctcgt
      541 gatgtcttga cagctgcttt tgaagaaaca gctaagctct tggaagaaaa gaaagtcgcg
      601 gctcaactgg ctagcgagag tatcgatgtg acgcttccag gtcgtccagt tgcgactggt
      661 caccgtcacg ttttgacaca aaccagtgaa gaaatcgaag atatcttcat cggtatgggt
      721 tatcaagtcg tggatggttt tgaagtggag caagactact ataactttga acgtatgaac
      781 cttccaaaag accacccagc tcgtgatatg caggatactt tctatatcac tgaagaaatc
      841 ttgctccgta cccacacgtc tccagttcag gcgcgtgcta tggatgccca tgatttttct
      901 aaaggtcctt tgaagatgat ctcgccaggg cgtgtcttcc gtcgcgatac ggacgatgcg
      961 acccacagtc accaattcca ccaaatcgaa ggcttggtag ttgggaaaaa tatctctatg
     1021 gctgatcttc aaggaacgct tcagttgatt gtccaaaaaa tgtttggtga agagcgtcaa
     1081 attcgtttgc gtccatctta cttcccattc acagagccat ctgttgaggt ggatgtttct
     1141 tgcttcaagt gtggtggaga aggctgtaac gtatgtaaga aaacaggttg gatcgaaatt
     1201 atgggagccg gtatggttca cccacgtgtc cttgaaatga gtggtatcga tgcgactgta
     1261 tactctggtt ttgcctttgg tcttggacaa gagcgtgtag ctatgctccg ttatggaatc
     1321 aacgatatcc gtggattcta ccaaggagat gtccgcttct cagaacagtt taaataatga
     1381 ttagaaaagt agaaatggca gatgttgagg tgttggctaa aattgccaaa caagcctttc
     1441 gtgaaacctt tgcgtatgat aatacggaag agcagttaca ggaatacttt gaagaggctt
     1501 atagtctgaa aactttgtca actgagttgg gaaatcctga ctctgaaacc tatttcatta
     1561 tgcatgagga ggagatagct ggttttctca aagtcaactg gggaagtgct caaactgaga
     1621 gagaattaga ggacgctttt gaaattcaac gcctctatgt gctacaaaaa ttccaaggat
     1681 ttggactagg taagcaactg tttgaattcg cacttgaact tgctacaaaa aatagttttt
     1741 cttgggcttg gctaggtgtt tgggagcata atacaaaagc tcaagcgttt tataatcgat
     1801 atggttttga aaaatttagc caacatcatt ttatggttgg tcaaaaagta gatacggatt
     1861 ggttactgag aaagaaatta aggtaagaag aggattcttc tattgaaatg ataggaaagg
     1921 aaaagaacca gtgtggcaat ggtcattctg gagaactaaa ttatgcttat atcttataaa
     1981 tggttaaaag aattggtgga cattgatgtg ccatcacaag agttggctga aaaaatgtca
     2041 actacaggaa tcgaggtcga aggtgtcgaa tcaccagctg ctggtctctc aaaaattgtc
     2101 gtcggtgagg tcttgtcttg cgaagatgtg ccagagactc acctccatgt ttgtcaggtt
     2161 aacgttggcg aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgctgggatc
     2221 aaggtcatgg tggctcttcc aggagctcgt atcgctgata actacaaaat caaaaaagga
     2281 aaaatccgtg gtttggagtc acttggaatg atctgttcac ttggtgaatt gggaatttct
     2341 gactcagttg tgcctaagga attcgcagat ggcatccaaa tcttgcctga agatgccgtg
     2401 ccaggtgagg aagtcttttc ttacctagac ttggatgatg aaatcatcga actttccatc
     2461 acaccaaacc gtgcagatgc cctttctatg tgtggagtgg ctcacgaagt ggcagccatc
     2521 tatgacaagg cagtcaactt taaagaattt actctaacag aaactaatga agctgcggca
     2581 gatgcccttt ctgtcagcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     2641 gacaatgtga ccatcgcacc aagtccacaa tggttgcaaa accttctcat gaacgaagga
     2701 atccgtccca tcaataacgt agtggacgtg accaactaca tcctgctcta ttttggtcaa
     2761 ccaatgcatg cctttgactt ggataacttt gaagggactg acatccgtgt gcgtgaagcg
     2821 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     2881 ctagtcatca ctgtcgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     2941 acagaaatct ctgaaaaatc tagtcgtgtt gtccttgaag ctgctgtttt caatggcaaa
     3001 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     3061 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     3121 gaacttgcag gtgcgacggt gcgtaagggc atcgtttcag cgggtgagct tgatacttca
     3181 gatgtagaag tttcttcaac ccttgctgat gttaaccgtg tcctcggaac tgagctgtct
     3241 tatgctgatg tagaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     3301 agctttacag tcagagtccc acgtcgtcgt tgggatatca caatcgaagc tgacctcttt
     3361 gaagaaattg ctcgtatcta tggttatgac cgcttgccaa ctagtctacc aaaagacgat
     3421 ggtacagcag gtgaattgac agccacacaa aaactccgcc gtcaagttcg tactattgct
     3481 gaaggagcag gtttgacaga aatcatcacc tatactctaa caactcctga aaaagcagtt
     3541 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     3601 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     3661 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     3721 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     3781 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taagggaatc
     3841 cttgaagccc tatttactcg tttgggactc caagtaacct atacagcaac atctgaaatc
     3901 gctagccttc atccaggtcg tacagccgtg atttcactcg gtgaccaagt tcttggtttc
     3961 cttggccaag tgcatccagt cactgccaag gcttacgata ttccagaaac gtatgtggct
     4021 gagcttaacc tttcagctat cgaagctgcg cttcagccag cgactccatt tgtagaaatc
     4081 accaaattcc cggcagtcag ccgtgacgtt gcccttctcc tcaaggcaga agtgactcat
     4141 caagaagttg tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     4201 tttgacgtct tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     4261 accttccaaa atccagaaga tagcttaacg gacgaagaag tcgcacgcta tatggaaaaa
     4321 atccaagcat cgctcgaaga aaaagtcaat gcagaagtgc gttaaacgat agtatgatac
     4381 aaattccccc tctagtttat gaacactaga ggggtgattt tatataaaat aattaaaatg
     4441 tgatttctgt aaaaatacat ctatgatcag agttttgaaa acttacaatg tctaaatctt
     4501 taacatagta gtggttttta ggcaataaaa tatgatctat tgttgcatta aaaagttttg
     4561 gactttggct attccaagtt cctctttcaa aaggtggcag tacatttaat gcgtccctat
     4621 gagagcttat ttttgcaagt gctccatgac gcatagttgc attaaaatca cctgcaataa
     4681 tagcctttgg atattttgaa gccaattgat tatgaatgat gtttaagtct tgcttccaga
     4741 tttccattaa acctggcaga ggaggagcag tatgcaaggc aatgatatct ggtatatttt
     4801 gttttctcga atgtaataca attgtcccga accgtgttgt atgaaaagtt ttagcttctg
     4861 tatagaaacc ataacttttc ttgacaatca cagtcacagg agctattcca ctattggtag
     4921 gtggagaagt gaaaatatca tagttggcca tagaaagtcc aacttgatga aacaatagtt
     4981 tgattctctg gttttcttgc tcacctctga tattggtagc tagttcaggg aatatagcca
     5041 tatcggcgtc aaaatggcta aaaattcgct caatatgttg tgcttctatt tgattagcga
     5101 cgttccaagt tactaatttt aaggttttag tcttatttga tgcagaagaa agggttttat
     5161 ctgttccgaa taatagtaat atgagcgata gtaagagcaa aatgccagag taaaaccgta
     5221 tttgtttatt tttcttgtaa aaagatagga aaaaaaataa gaaacttaaa atagcagcca
     5281 tagttgcagt agctaagggg aaggcataaa tctgtgccaa gataggttgg gtagatagcc
     5341 aaatgttaag attagaagat gggaaaaaag aataagttat gatagggata acaaagagaa
     5401 tgaccgaaag ggcagagaga aatgttttaa tcattgtgtg agtacctcaa tttgcaatgg
     5461 ttgctcggag ctaatgtgac tttgtgactt tacttgattg atattctttt tcttgtcttc
     5521 ctcatagatt aagtacaacc caagtaaaaa aagtccaatt taagattgaa atgattaaaa
     5581 ggcacagaga tgcaagacaa ttatactaca aaaggtaaac atttgacaat cgatagccgt
     5641 cgcttaatcg aaagatggaa aaaagaagga aaatcaaata gagaagttgc ctctctactt
     5701 ggaaaagctc ctcaaactat ccacactgaa atcaagcgtg ggacagtccg aaaatgtctt
     5761 ggaaaagggc gcttcaaaga ggtttattct gccgactacg ctcaacagtc ttatgaaaac
     5821 aatcgcaagc gctcggtcaa gaaatcaagc ttgaccaagg aactaaagga aaagattctc
     5881 cactatacat aaccaaaaat tttcgcctga aatgatggtt atggctaaag gggttaacgt
     5941 gggaatttca accatttact attggattca tcgtggaaaa ttggggttaa gcaagcagga
     6001 tctgctttat cctagaaaag gaaaatcgct taagaaatag gctagcacca actttaaacc
     6061 cgctggtcaa tctatcgaat cataattcgc tcattttttt aaaaatacat agacgtaaaa
     6121 gaaagagggt taagtgatga agaatagtgc tattgggagt aattggaagg atgtccatct
     6181 gagctcttta gcaaggagga aatccttgaa agtgatatgc gagtagctat catgagcgag
     6241 ttgattgaag ccagaaataa gcaaggaatc agtcagaaaa agctagagga actcagtgga
     6301 gtgagtcagc ctgttatagc taggatggag acaggtaaga ctagtccaca gttggacaca
     6361 gtcttaaaag tcctagctag tctaggaaag atactagcag tcgtccgact tgaacagggg
     6421 aaaagttgac tagaatcagt tatagtcttt tctaataaca agccatagtc acttataaga
     6481 attactaata acgcgtttga gcattctaac taaaatacag ctaaaaacaa gttataaaag
     6541 ggatttgagg catgtgtctc aagtcttttt cttttgtcta aaatagaggt atagtttcaa
     6601 actatatcaa agcctaattt tttacaatta tacagatgct ttcttttctg ttaagatagt
     6661 ttcaacaaca aattttggag gacacatcat gtcaactaca atcatcggtt tccctcgttt
     6721 gggcgaattc cgtgaattaa aatttacaac tgaaaaatac tttagaaaag aaatctcaga
     6781 agaagaactt ttagcagcag caaaagactt gcgtgctaaa cactggaaca ttgtcaaaga
     6841 aaaaggcatc actgaaattc catcaaatga cttttctcac tatgataact tcctagatgc
     6901 ggctttcctt ttcaacgtgg tgcctgcatc cgttcaaaac ttggacttgt ctgaccttga
     6961 gcgctacttc gctttgggac gtggttacca gggagaaaaa ggggacgttc gcgcccttcc
     7021 aatgaagaaa tggttcaaca ctaactacca ctacatcgtt cctaaatttg aaaaagacac
     7081 tcaagtaaaa ttggctggtc acaagatttt cgatgagttc caagaagcaa aagaacttgg
     7141 attgaacact cgtcctgttc ttgtaggtcc attcactttc cttcaattgt cagactttga
     7201 agaaggcgtg aaagcagacg acttcgtaga tagcttagtg gctgcttacc aagaagtttt
     7261 tgctaaattg gctgaacttg gtgcgactcg catccaattg gatgaagcgg ctcttgtaaa
     7321 agacttgaca gctgaagaaa aagctctctt cttgaacctt tacaacaaac tcttggctga
     7381 caaaaaaggt cttgaagtct tgcttcaaac ttatttcggt gatgttcgtg acgtatacgc
     7441 tgaccttgta aacttgccag tagatgctat cggtcttgac tttgttgaag gtaagaaaac
     7501 tcttgaactc gttaaaggtg gcttcccagc tgacaagact ctctatgtag gtattgtcaa
     7561 tggtaaaaac atctggcgca acaactacga aaagagcttg gctgttcttg agcaaatccc
     7621 agctgaaaac atcgttttga caagctcttg ctcacttctt catgtgccat ttacaactgc
     7681 taatgaagaa tttgaaccag cactcttgaa ccactttgcc tttgcagttg aaaaattgga
     7741 tgaaatccgt gacttggatg ctatccgcaa tggtcaaggt tcagaagctc ttgcagccaa
     7801 caaagaactc tttgcgactg agcgtgttgg tgaaaatgct gaacttcgtg cgcgtatcgc
     7861 tggcttgaca gacgcagact acactcgttt gccagccttt gcagaacgtg aagctatcca
     7921 agaagaagct ttcaaacttc cagctcttcc aacaacaacg attggttcat tccctcaaac
     7981 aaaagaagtt cgtgccaaac gtttggctta ccgtaaaggt gaattgtctc aaaaagagta
     8041 cgatgctttc cttgctgaaa cgattgacga atggatcaag tggcaagaag atattgactt
     8101 tgatgtcctt gttcacggtg aatttgagcg taatgacatg gttgagtact tcggtcaaaa
     8161 cttgtcagga tacttcttct ctaaaaatgg atgggtacaa tcatacggta tgcgtggggt
     8221 aaaaccacca atcatctggg gtgatgtcac tcgtcttaac cctatcactg ttaaatggtc
     8281 tagctatgca caaagtcgta caaacaaacc tgttaaaggt atgttgactg gacctgttac
     8341 catccttaac tggtcattcc cacgtgaaga catctctatc aaggattcta ctcttcaaat
     8401 cgcccttgct atcaaggatg aagtgcttga ccttgaagct gctggtgtga aaatcatcca
     8461 aattgatgag gctgctcttc gtgaaaaatt gccactccgt cgtagtgact ggtacgaaga
     8521 ttaccttgac tgggcaattc ctgccttccg cttggtacac tcaacagtag cgtcagacac
     8581 acaaatccac actcacatgt gttactcaga atttacagat atcatcccag ctatcgataa
     8641 catggatgca gacgttattt cctttgaagc cagccgttca aaccttgaaa tcttggacga
     8701 actcaaagcg aaaaacttcc aaacagaagt gggacctggg gtttacgata tccactcacc
     8761 tcgtgtacca aacgaaggcg aaatcgacaa cacaatcgaa gccatccttg ctaaagtgcc
     8821 aagcaagaaa gtttggatca accctgactg tggtttgaaa acacgtggta tcccagaaac
     8881 aaaagaaagc ttgatccgcc ttgttgaagc agctaaagct gcgcgtgaga aattgtaaga
     8941 ttggatttct ctccatacag tggttgttca aaaagaaatc aactagaaaa ggttattaca
     9001 tatgtcacgc caaacaccgt cactctcatt tgaagtgttc cctccaaacc cagccgtggg
     9061 taatggtaac attatttcag ccttgcagga tatgcaggag ttggctcccc attttatcag
     9121 tgtaactgcc agcaataata aatttaatat caaggaaacg acggttcgtt tggctgactt
     9181 tatccaaaat gacttggcga ttccgaccat tgcccacttg ccagctattt atctaactaa
     9241 ggacaaggtt gctgaaacta ttgttgactt ggacaaagtt ggggttcaga aaatcttggc
     9301 tcttcgtggg gatattattc cagacgtaga accacaaaag gatttccgct atgcaaccga
     9361 cttgattgag tttatcaagg aacaagcccc tcactttgat attattggag cttgctatcc
     9421 agaagagcat ccagattcgc caaatcagat ttcagatatt caaaatctta agaagaaagt
     9481 ggatgcaggc tgttcgagcc tcgtaactca gctcttcttt gacaatgagc gcttctatga
     9541 ttttcaggac aagtgtatct tggctgggat tgatgttccc attcatgcag gaattatgcc
     9601 aattctgaat cgaaatcagg ctctccgact cttgaagact tgtgagaata tccatcttcc
     9661 acgcaaattt aaagccatct tagacaagta tgagcatgac cctgagtcgc tcagagcagc
     9721 aggacttgcc tatgcagtgg accaaatcgt ggacttggta actcaggatg ttgccggtgt
     9781 gcatctctat acgatgaata atgctgatac agcaaaatac atccatcaag caacccatgc
     9841 cttgtttaat caccagtctc taggataata aaagcaaacc attcttctca ggtgagggga
     9901 atggttcctt tttaatggta aagacctcac tttttaagaa aaatatgata aaataaattc
     9961 tgtacgtact tgatacaaag atgaaggtat taaataatac aatgcattta aactgtaaga
    10021 tttaacgaca cgagtgagtc aaatcgatgt tatttgacga gagagttagt aaagcattta
    10081 gctaatcgcc cgatagcgat tagcgtgaaa gctttagata ctttagtatt aaacctttct
    10141 aatgatgtat cttgaaaact gaacttgcct acaactctgt ggaaaaagat aaatctccct
    10201 aggagtagtc gctccgtcgt tcgatttcct atcttccttt gagttgcttg acggcttggt
    10261 atcttgagta attgaacacg gccgaaaagc tgtgtaaaaa agataaactg tcttgtcttc
    10321 atcgaagact tcgtcagttt cctattttta ctttgctttt gacgtccttg gtatcttgat
    10381 ctttgtaggc aaggcgtata atttcatcaa tcaaaagggg attaaaatgg caaaacaagt
    10441 gtttcaaacg acttttgcgg gtcgtgagtt aattgtagag actggtcagg ttgctaagca
    10501 agcaaatgga tctgttgtcg tacgttacgg tgagtcaact gtcttgactg ctgccgttat
    10561 gtctaagaaa atggcaactg gggatttctt cccactccaa gtcaactacg aagaaaaaat
    10621 gtatgcggct gggaagtttc ctggtggctt tatgaaacgt gaaggacgtc cttcaacaga
    10681 tgcgaccttg acagcgcgtt tgattgaccg tccgattcgt cctatgtttg cggaaggttt
    10741 ccgtaatgaa gtccaagtca tcaatacagt gctttcttat gatgaaaatg catctgcacc
    10801 aatggctgct atgtttggtt catctttggc actgtctatt tcagatattc catttgacgg
    10861 accaattgct ggggtacaag tgggatatgt agatggccaa atcatcatca acccaagtca
    10921 agaacaagca gagcaatctc ttcttgaatt gacagtagct ggaaccaagc acgctatcaa
    10981 catggtagag tctggtgcca aagaattgtc agaagaaatc atgttggaag cgcttcttaa
    11041 agggcacgaa gctgtcaaag aattgattac cttccaagaa gaaatcgttg ctgctgtcgg
    11101 taaagaaaaa gcagaagtgg aattgcttca cgtggatgct gaattgcaag ctgaaatcat
    11161 tgcagcctac aacagtgacc tccaaaaggc agttcaagta gaagagaaat tggcccgtga
    11221 agctgcaact caagcagtga aagaccaagt gactgccgtt tacgaagaaa aatatgcgaa
    11281 ccacgaagaa tttgaccgta ttatgcgtga tgtggctgaa atcttggaac aaatggaaca
    11341 cgcagaagtg cgacgtttaa ttacagaaga caaggtgcgt cctgatggtc gtaaggtcga
    11401 tgaaatccgt cctttggatg cggttgttga cttccttcct cgtgtacatg gttcaggtct
    11461 ctttactcgt gggcaaactc aagctctttc agtcttgacc ttggctccga tgggagaaac
    11521 tcaaatcatt gatggtttgg atccagagta caagaaacgc tttatgcacc actataactt
    11581 ccctcaatat tctgtagggg aaacaggtcg ttacggtgcg ccaggtcgtc gtgaaatcgg
    11641 tcacggtgct cttggtgagc gtgctcttgc tcaagtcttg ccaagcttgg aagaattccc
    11701 atacgctatc cgtctagtag cagaagtttt ggaatcaaac ggttcttcat ctcaagcttc
    11761 tatctgtgcg ggaactcttg cccttatggc tggtggtgtg ccaatcaagg cgccagtagc
    11821 tggtattgct atgggactta tctcagatgg aaataactac acagtattga cagatatcca
    11881 aggtttggaa gatcactttg gagatatgga cttcaaggtt gcaggtactc gtgatgggat
    11941 tacagccctt caaatggata tcaagattca agggattact gcagaaatct tgacggaggc
    12001 tcttgctcaa gccaagaaag cgcgttttga aatccttgat gtcattgaag caaccattcc
    12061 agaagttcgt ccagaattgg ctccaactgc tccgaaaatt gatacgatca agattgatgt
    12121 ggacaagatt aagattgtca tcggtaaggg tggagaaacc atcgacaaga ttatcgctga
    12181 aacaggtgtt aagattgata tagacgaaga aggaaatgtg tctatctact ctagtgacca
    12241 agatgctatt aaccgtgcca aagaaattat tgctggtttg gttcgtgaag ccaaagtgga
    12301 tgaagtttac cgtgctaaag tcgttcgtat cgagaaattt ggtgcctttg ttaacctctt
    12361 tgataagaca gatgcccttg ttcatatctc tgagatggct tggactcgta ccaatcgtgt
    12421 agaggatttg gtagaaatcg gggatgaagt tgatgttaag gttatcaaga ttgatgaaaa
    12481 aggccgtatc gatgcctcta tgaaggctct tctacctcgt ccgccaaaac ctgagcatga
    12541 tgaaaaaggt gaaaagtctg agcgccctca ccgcccacgt catcaaaagg atcacaaacc
    12601 taagaaagaa tttacagaaa caccaaaaga ttcagaataa gaaaaggaga aatgtatggg
    12661 gtggtggcgc gaaaccattg atattgtaaa agaaaatgat ccagcggccc gcaccacttt
    12721 ggaggttttg ctgacttatc caggtgtcaa ggccttggcg gcccaccgtc tctcgcattt
    12781 tctctggaag cacggcttca aactattagc tcgtatgtac agtcagtttt ggcgcttttg
    12841 gactcagatt gagattcatc caggagccca gattgattca ggtgttttta ttgaccatgg
    12901 ttctggtctg gtgattggag agacagcgat tgttgaaaaa ggcgttcttc tctatcacgg
    12961 agtgactctc gggggaacag ggaaagactg tggcaaacgc catccgactg tacgaaaggg
    13021 agccctcata tcagcccatg cccaagttat cgggcctgtg gaaattggtg aaaatgccaa
    13081 ggtcggtgct gcagcagttg tcgtagcaga tgtacctagt gacgtgacgg ttgtcggtat
    13141 tccggccaag attgtccgtc ttcatggtaa gaaagatgag cctgtcattc acgaagtcga
    13201 agaaaaacga gagtattatg tcaataaact cgagcaggct aaagatgcca gtcacagatc
    13261 gtctggtttg tagaggatac ctatatgatt caagcaagaa acaagttaag ccaagaggag
    13321 ctatctgaag cgaaaaaagt aattaactgt tgccaaaact atgacggtac ctatcgcgat
    13381 ccctatctct ctaacatgct taattttgac ccaaacatgc ccgccttttt cctttattat
    13441 gaaaaaggcg aacttgttgg tttattaact gtctatgcag atgaccaaga tgtagaagta
    13501 acgatactgg ttcatccagg tcatcgccgt caggggattg cgcgtgcatt gtttactagt
    13561 tttgagagag aaatagcttc tttccccatt cggtcagtca cttttcagac agaacgtatt
    13621 tttttagaga atcatcctga ctttgccagt aactggggac taatcgagga tgaagagaca
    13681 gaaacttggt taggtaagga tagaagacct tatccgttag caaatgtttc ccatcttgaa
    13741 gttttgttag cagatagttc gtatcaggat caaattagtc aattaaaatt tcaggcattt
    13801 tcagaggaac atgaatcgag agaagttgtg gatagatatg tcgctgaagc tctgaaggat
    13861 ccagaaagtc gcttatatat tttattaaaa gacggtcagg ttattgggac ttgtacggtt
    13921 gatttatcga ctaatacgaa ttacttctac ggtttagcaa tattggaacc tgaacgtgga
    13981 aaaggctatg gaagctactt agcaaaatcc ctcgtcaacc aactaattga gcaaaatgac
    14041 aaggaatttc agattgcagt ggaagatagc aatgtaggtg ccaaacgttt gtatgaaaaa
    14101 attggctttg tcaaacagac tcaggtggtt tatctgaatg agaaaggagc aagggattcc
    14161 gaagtgtaga gatattcgga ctgaaattta cttgaacttt tagtgatgaa actaattgtt
    14221 cttggatttc agctttcctg attatgattt atgattaaaa tctatgacac catgtctcgt
    14281 gatttgcgag aatttgtccc gattgaggac ggcaagatca agatgtatgt ttgtgggcca
    14341 acggtgtaca actatatcca cgtgggaaac gcccgttcga cggtagcttt tgatacgatt
    14401 cgtcgctatt ttgagtaccg tgggtataag gttgcctata tttccaattt tacagatgtg
    14461 gatgataaga ttatcaaccg tgccagggaa gaaggcatca cgcctcagga ggttgcggat
    14521 aagtacatcg ctgcctttcg tgaggatgtg acggccttgg gcgtgaaacc tgcgactcgc
    14581 catccgcgtg tagtggagtt tatggcagac atcatccgtt ttgtggaaga cttgatcgag
    14641 aaaggctttg cctatgagag tcaaggggat gtctatttcc gtgtagaaaa atcccacaac
    14701 tatgctaaat tggctaataa aaccttggaa gatttggagc taggtgcttc aggtcgtacc
    14761 gatgaagaaa cggctcgtaa ggaaaatcct gtagactttg ctctatggaa atcttccaaa
    14821 ccaggtgaga tttcttggga tagtccttgg ggacctggac gtccgggttg gcatattgag
    14881 tgttcagtca tgtcgacaga gattttaggt gataccattg atatccacgg tggtggagct
    14941 gacctagagt ttccacacca caccaatgaa attgcccaat ctgaagctaa aacaggcaag
    15001 gcttttgcta actactggat gcacaatggc tttgtcaata tcgacaatgt caaaatgtct
    15061 aagtccttgg gtaacttcat tacggtacac gatgccctta aaactcttga tgggcaagta
    15121 cttcgtttct tctttgcgac ccagcactac cgtaagccta tcaacttcac ggaaaaggca
    15181 gttcgcgatg ccgagaccaa tctcaagtat ctgaagaata cttacgaaca accatttaca
    15241 ggaaacgtgg atgcccaaga gttacaaaac tttaaagata agtttgtagc agctatggat
    15301 gaagatttta atgctgccaa cggtatcaca gttgtctttg aaatggccaa atggatcaac
    15361 tcagggaact atgatgcaag tgtcaagcaa gctcttgcag atatgttaga aatttttgga
    15421 attgtctttg ttgaggaagt tttggatgca gagattgaag acttgattca aaaacgccaa
    15481 gaggcgcgtg ccaatcgaga ctttgagaca gcagaccaaa tccgtgacca attggttact
    15541 caaggaatta agctccttga taccaaggat ggagtgaggt ggacacgtga ttgatgtcaa
    15601 tctcattaac gggattgcgc tagcctttga gggggatgcg gtgtattcta tgtatattcg
    15661 ccgtcacctc atcctcaaag gtatgaccaa acccaataaa ctccatcaag aagcaaccaa
    15721 gtatgtgtca gccaaggctc aggctcgcct gattgctctc atgttggagg agcaggtcct
    15781 aacggaaaaa gaagaagaaa tctacaaacg tggccgcaat accaatagcc acacaaaggc
    15841 taaaaatgca gatgtcgtga cttatcgtat gtccacggga tttgaagcgg ttatgggcta
    15901 tctccatatg actgagaatc tggaacgtct tgagagtttg gtttcatggt gcatccaaaa
    15961 agtggagggc tagaacatga gggaaaaaga actacaagac tggtttcctg aggctcggat
    16021 ttcagaccaa ccagtagaga aagagggcta tctcacgctc cctttagctt ctcagcagtg
    16081 gattttgctg gaggaagctg ggctcagcga gcgtgaaaag cagttggttg cccttttgac
    16141 ccagcaggag caggctcgtt cgctaaaccc ttggtattcc tatctggttg aaggcaaggg
    16201 acaggcaccg caagttttta aaaagattca gttggtttat tgccatcttt cttattttca
    16261 gcaggaaaat ctggcttctt ggctagatat gatgcggact ctttttccga attgtcagac
    16321 agtgctacag gtcggatctc aggattatgt tttcgtgctt caacaagaca aatacactta
    16381 tgtaagagat attttaagtg atacgattga agcggttgag tatgactttg gacttcgtct
    16441 ttctatcatg ttgggtcagg tttggtctca gacgggacat caagccctat cagacttaat
    16501 caaagctgag cgggatttgt tcaagacatg gtggcgtcag ggtcaccaag gtgttcatac
    16561 tttttctcag ctctatcttt ggagtatggg agaaagactc gtggacttga agccaatcaa
    16621 ggaatgtcta caccagatga ttttggatca agatcagatt caggaaatca ttctctctct
    16681 ttgggaaaat agtgctgttc tcactaaaac agcccagcaa ctctatctgc accgcaattc
    16741 tctccaatac aagattgata aatgggaaga gttgacaggg cttcagttga aagagttgac
    16801 cgacctgacc ttgtgttatc aattgatttt aggttctttg tcaactatag ttggtttgta
    16861 aagaagttaa tatttggaga agaggatggc catcttctcc atttttatgt gcagagttat
    16921 agtggcttga tgctgggaaa gtacactgtg actgctaaaa cattcctaga agttgctttg
    16981 atttccctaa tctatttatg tgaattttat gttattttac tataacagtt gttgctaagc
    17041 taaataatag tggggaagtt tatttagacg taagcattga agataatcag ggaggtagtg
    17101 ggtataattt cagttctgtt tcaagtagct cacaaacagc taaatatgaa ggaactggtt
    17161 ataataacaa ttcatcatta tatataacga ttgataaaac gtctgatgca acagctcttt
    17221 tgaaattaaa gttgaataat gttgataatc aacctgctac tgaagttcct agttcaggaa
    17281 ttactgtaaa attaaatgct aaagataatg ctggaaactg gacaagtgct tcgaataaaa
    17341 aagaagtaac agtaaaaatt gtttctgcta aaccgacata tccagacaaa attttagtga
    17401 aaaatcctga taatataaaa gatacagaaa aaaatgccat tattgaaaaa ttgaaagagg
    17461 caaataaaaa tcatccagca ggagctccaa cctttgctaa aggtgaagga gagcatgcaa
    17521 atgatattgt agcaacttat tcagatggta caacttatta tgtaccgtta aatgatgtga
    17581 caaaatatgc gaggtagtgg ctgtaccact cacttattca cctccccgtg atttgtagta
    17641 gtgataggct ttctcactat tattataaaa caaaataaag atcacaacac tttttcattc
    17701 tgtgttgtgc cttgagtgaa acgaaaggaa tgaattataa atatgaaaag tatagtcact
    17761 aacatagatg agcgcttgcg tactcgccta cgagtgatta tctggaagca atggaagaag
    17821 aaatcgagac gattatgggg attgcttaag ttaggggttc ctaaatggat agcagataag
    17881 gtatctggct ggggcgagca ctatcaatta tattaaaatg aaataagaat aggacgaatc
    17941 gatcagggaa gtcaaatcga tttctaacaa tattttagaa gtagaggtat a
//
LOCUS       DAVBNZ010000045        17904 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000045 DAVBNZ010000000
VERSION     DAVBNZ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17904
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.045"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            1..789
                     /locus_tag="VQ860_001567"
                     /pseudo
     CDS             1..789
                     /locus_tag="VQ860_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1105..2079)
                     /gene="pta"
                     /locus_tag="VQ860_001568"
     CDS             complement(1105..2079)
                     /gene="pta"
                     /locus_tag="VQ860_001568"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET3119968.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(2123..3019)
                     /locus_tag="VQ860_001569"
     CDS             complement(2123..3019)
                     /locus_tag="VQ860_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3119969.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(3016..3834)
                     /locus_tag="VQ860_001570"
     CDS             complement(3016..3834)
                     /locus_tag="VQ860_001570"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET3119970.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(3818..4489)
                     /locus_tag="VQ860_001571"
     CDS             complement(3818..4489)
                     /locus_tag="VQ860_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET3119971.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            4617..5186
                     /locus_tag="VQ860_001572"
     CDS             4617..5186
                     /locus_tag="VQ860_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET3119972.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            5299..6258
                     /locus_tag="VQ860_001573"
     CDS             5299..6258
                     /locus_tag="VQ860_001573"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3119973.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            6268..7383
                     /locus_tag="VQ860_001574"
     CDS             6268..7383
                     /locus_tag="VQ860_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3119974.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFTNNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            7388..7735
                     /locus_tag="VQ860_001575"
     CDS             7388..7735
                     /locus_tag="VQ860_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET3119975.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKEVTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            7743..7958
                     /locus_tag="VQ860_001576"
     CDS             7743..7958
                     /locus_tag="VQ860_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3119976.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            8041..8682
                     /locus_tag="VQ860_001577"
     CDS             8041..8682
                     /locus_tag="VQ860_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET3119977.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            8700..9389
                     /locus_tag="VQ860_001578"
     CDS             8700..9389
                     /locus_tag="VQ860_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3119978.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(9386..10066)
                     /gene="radC"
                     /locus_tag="VQ860_001579"
     CDS             complement(9386..10066)
                     /gene="radC"
                     /locus_tag="VQ860_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET3119979.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(10109..12400)
                     /gene="pcrA"
                     /locus_tag="VQ860_001580"
     CDS             complement(10109..12400)
                     /gene="pcrA"
                     /locus_tag="VQ860_001580"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET3119980.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQNCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDTDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(12591..13396)
                     /locus_tag="VQ860_001581"
     CDS             complement(join(12591..13019,13022..13396))
                     /locus_tag="VQ860_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET3119981.1"
                     /translation="MNDEASKQLTDARFKRLVDVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADLGIHESNLIRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKTNRPKKQLANYSGKKKFHAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNFIAGIINHELGF"
     gene            complement(13776..14636)
                     /locus_tag="VQ860_001582"
     CDS             complement(13776..14636)
                     /locus_tag="VQ860_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET3119982.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(14652..15929)
                     /locus_tag="VQ860_001583"
     CDS             complement(14652..15929)
                     /locus_tag="VQ860_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3119983.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(15922..16473)
                     /locus_tag="VQ860_001584"
     CDS             complement(15922..16473)
                     /locus_tag="VQ860_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3119984.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(16489..17748)
                     /locus_tag="VQ860_001585"
     CDS             complement(16489..17748)
                     /locus_tag="VQ860_001585"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3119985.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT         5439 a         3906 c         3265 g         5294 t
ORIGIN      
        1 agaagaatca ccaaatccct cgtatcatca accaaaagat tgctcaaaag ttaattgaaa
       61 agatttctat gactgatatt gcccatcagc tttccatctc aacttcaact gttattcgta
      121 agctcaatga ttttcacttt gagcatgatt tttcgcgtct tcctgagatt atgtcttggg
      181 acgttgaaac agtccgggga gtgactgttt caatcgggag atggagatga gctttattgc
      241 tcaggacttt gataagctca atatcataac tgttcttgag agcagaacac aagccatcat
      301 ccgaaatccc atgaatacaa ggctatcaag cgctactgga aactcattca acaggatagc
      361 cgtaaactga gtgataagcg attttatcgt cctacttttc gtatgcattt aaccaataaa
      421 gagattttag acaagctttt gagctattca caagacttga aacatcacta tcagctctat
      481 caactcttgc tgtttcactt tcagaataag gaaccggaga aatttttcgg actcattgag
      541 gacaatctaa agcaggttca tcctcttttt cagactgtct ttaaaacctt tctaaaggac
      601 aaagagaaaa tcgtcaacgc ccttcaacta ccctattcaa acgccaaatt ggaagcgacc
      661 aataatctca tcaaacttat caagcgcaat gcctttggtt ttcggaactt tgaaaacttc
      721 aaaaaacgga tttttaccgc tctgaatatc aaaaaagaaa ggacaaaatt tgtcctttct
      781 cgagcttagc ttttcttcaa cccactacag ttgacaaaga gccagaaaac gcataatagc
      841 aggtgtcaag acacttaata ttatgcgttt tctcatgaaa aaattctctt ttcatactca
      901 tttaaaatca aaaagggaaa ttatcgtttt acggacatac atattacaga tttctatagg
      961 tcgtgtatag acaggatatc atcgcttgga agttttcctt tttgacacca atcagtaatt
     1021 tagttctcag gaattaatgg cagtgctttt cgtacatagt ttcataacta cagtatagca
     1081 tagtatatcg ctttatagtt ttcactattg atgaactgct tgagctgctg tgatgagggt
     1141 caacttgtaa acatcatctg cattacatcc acgagaaaga tcattaactg gcttgtttaa
     1201 accttgcaaa acaggtccta cagccgcaaa gccacccagg cgttcagcca tcttgtaacc
     1261 gatatttccg gcctcgatac ctgggaagat gaagacattt gcttgaccag ctaccgtact
     1321 tccaggagct ttcagagctg cagtttcagg aacaaaggct gcatcaaatt gcaactcacc
     1381 atcgatttca aggtcaggac gcaagtcgtg agcaatttta gttgcttcaa cgaccttatc
     1441 aacgctttca ccaaaccctg aacctttagt agaatagctc aacatggcaa ttttaggttc
     1501 gatgccaaac atcttagctg tgattgctga gttgatggca atttcagcca aggcttctgc
     1561 atctggattg atgttaatgg cacagtctcc aaataggtaa cgttccgtac cacgaaccat
     1621 gaggaaggct cctgaagtac gagttacatt tggacgagtt ttgatgattt gtagagctgg
     1681 acgaactgtt gaagctgttg agtgaatcgc tcctgacacc attccatcaa ccaagcccaa
     1741 gtaaaccaac atcacaccaa agtagttgac atcttcaacc aaaaccttgc gtacatcttc
     1801 ttcagtcatt ttgcccttgc gacgctccac caaggcagaa accatttctt caaattgagg
     1861 ataatgttga gggtcgatga cctcataacc atccatgatt ccttcaattt caagataaat
     1921 tttaattttt tcaggatttc caagcaaaac aggaatcact tctgtttctt ttactaagcg
     1981 ttttgttgct tgaagaatac gaggctcttc cccttcaggg agaacgatac gagcattttt
     2041 accaacaagg ttggctttga gactttcaaa aacttccatg agttttctcc tttaagataa
     2101 taattatact ctgagacagt ttttatagag tattagttga taactgggta ataaggttac
     2161 tgaaatcatc cggcaaggga ctttctaact gcaagtcttg ctctaaaaat ggatgataaa
     2221 aggataggta atggcaatgc agagcctgac gttgaatacc atcttccaga ctaccaccat
     2281 acaaatcatc tcccagcaaa ggaaaaccga tatgagaaaa atggactcgg atttgatggg
     2341 ttcgaccagt gtgcaggtga atatagacca agtgaatatt tccataagaa gctacaatct
     2401 tgtatgaagt atgggcatac tttccgcctt tagccactcg tctggtaata atggaatctt
     2461 catcacgcgc aatcggagca ataatttccc cttctggctc caaatgtcca tctcccttaa
     2521 ccaaagcaaa gtagcgtttc tcgatagatt tcttctgcaa ctgcttgtct aatcgtgcat
     2581 gggcataacc gtgcttggca aagagcatca agccagaagt gtccctatct agtctggtaa
     2641 caatgtgaac ctgctgattt tcataatttt gcttgacata gtaacccttg ataaaattgg
     2701 caatggtgtt agagtgattg acactaggaa tagaagccac tccatagggt ttattcaaga
     2761 ctagaaagtg gtcatcctca tagagaatat ctaatggatg ctcaatagcc tccaaggttt
     2821 caaagccttc ctcagcggga atgtaaatgg taacgtagtc tccaacgtcc aatagatacg
     2881 ttgcattttg cggttgatta ttgaccagaa tagctccacc tcgaaactta atcttagcca
     2941 gcaatccctt agaaacctcg tgctttttta aaaaggtctt aaccttgaca tgttcatctg
     3001 cgataaattc aaacctcatt catccacctc accgataaag gcatccttaa cacggttcca
     3061 gaaactggta tggctaggag tcgcgacaaa gtgaatctta tgatggtcga tttgatactc
     3121 aatacgctca atattacgga aagaataaac gctattgtca accgaaatag tatgataatc
     3181 gtttcttgtt ggaataagtt caatcttatc cttcttaggc acaataatgg aagagcccag
     3241 tgttcgataa acacgattat taaggctggc aatttccgtt aattgcaaag cttcaatggt
     3301 agggtgtaaa acagcaccgc caagagactt gttataggca gtactaccag tcggtgtcga
     3361 aactgttagc ccgtctccac gaaaacgttc aaagggaaca ccatttatta caatatctgc
     3421 caccatggtt cgatcagacc tgcggatgct ggcttcgttg agtgctctga aaatcttaac
     3481 ttcaccattt tcaagaaaga ccttcacatt cagaacaggg taagaaaccc ttgccccagt
     3541 atctagctgc aaattagtca ctagcttgtc caactcaaaa tcacgataat ctgtatagaa
     3601 gcccaaatgt ccagtatgaa gaccgataaa gcggaccttg tcaagctgat tttcgtactt
     3661 atgaaaggcc gacaagagca taccatcccc gccaatggaa atgacaatat ccggattggt
     3721 atcattgagt ataaactgat ttctcttcaa acgatctcgc aattcataca aaaccctttg
     3781 actctgcggt tttctattgg ctatcagatc aattcgttta cctgtattct tcatctgtat
     3841 cgtcactgtt tcctacaccg tcatttaatt ttctactcaa aggatcaaaa agtgcctggg
     3901 cttcttggat atcatcacga atttcaccca tttcttcatc caactgatgg gcgattctag
     3961 ctgtaatttc cagtcgcttc ttaatctcat ctgggaaatc cccttggtac ttgtagttga
     4021 gagaatgttc tatcgttgcc cagaaattca tggccaaagt acgaatttga atttctgcca
     4081 aaatagtctt agctccattg atggtatcaa ccgtatattc tactaccaca tgataggaac
     4141 gatagcctga tgcttttcta tgagtaatgt aatctcgctc ctgtatgatt cgcatatcct
     4201 gacgcttgtg caaaatatcc actacttcct tgacgtcatc tacaaactga accatcacac
     4261 gtaagccagc aatatcctgc aaatcgtgtt ccaaggtcgc ataagtaatg ccacgacgag
     4321 ccattttttc tttgatgctc tcaattggct tgactcgacc ggtcacaaac tcaattggag
     4381 aatgcttatt ttgcttacga tattgcttac gaataccacg aagtttaatc tttaactcac
     4441 caacagcttg aatgtaagga tctagaaatt cttcccattc taaggtcata tattctccct
     4501 tgttctcata ttatccgtca aaaatatctt tgattttttc tccagattca tatacaataa
     4561 atacaatgct tattatacca taaatccgct ttcaacgata aaaaaaggta agaaaaatga
     4621 aacatttaga aattgaattg aaaacactat tgaaaaaaga tgaatacaat cgtctaaaag
     4681 accagttcac aggtgtcact cctgttcttc aaacaaatta ctacatcgac acgcctgatt
     4741 ttgaactgcg agaaaagaaa gtcgctatgc gcattcgaac ctttgaagac tgggctgagt
     4801 tgacactcaa agtcccgcag agtgttggaa acatggaata caaccaaaaa ttgcaactaa
     4861 aagatgctga ggactatctg agtaaggaag aacttcctca aggactagta ctggatgaat
     4921 tggcgaaaca tggtatccaa agtaagaact ggcaggttct tggttgtcta acaacgcttc
     4981 gctatgaaat gaaaacagct attggtctca tggcactgga tcagagccga tactttgata
     5041 taacagatta cgaattggag cttgaagtgg aaaatcatga gcaaggcaaa caggatttcc
     5101 gacaattttt agagaaaaat cagatttcct accaaaaagc tccttcaaaa ttggttcgat
     5161 ttgtcaaaag tatgaaaaat agctgaaata atctccattt tttggtaaaa tagaaaagat
     5221 aaaaatacac aaatcccagt tcatatatgt aaggtaaata taactaggat ttataaagtt
     5281 tacagaggac ggtctataat gtcagataga aaaaacatga aacttttcgc actcaactct
     5341 aaccaagaga ttgcacaaaa aattgcccaa gctgttggtg tcccacttgg aaaactatca
     5401 tcacgtcaat tttcagacgg agaaatccaa gtaaatatcg aagaaagtgt ccgtggttat
     5461 gatgtttaca tcatccaatc aacaagtttc cctgtcaaca accacctaat ggaattgtta
     5521 atcatggtcg atgcttgtgt gcgtgcaagt gcccacagta tcaacgttgt ccttccatat
     5581 tttggctatg cacgtcaaga ccgcattgct tgtcctcgtg agccacttac agcaaaacta
     5641 gttgccaata tgctggttaa ggctggagtt gatcgtatcc tgactcttga tttgcatgcc
     5701 gttcaggttc aaggtttctt tgatattcca gtggataatc ttttcactgt tcccctattc
     5761 gcaaaacatt actgcgataa aggattgctt ggttcagatg ttgttgtcgt tagccctaaa
     5821 aattcaggtg tcaaacgtgc gcgtagcctg gctgaatatc ttgatgctcc tatcgccatt
     5881 atcgactacc ctcaagacga tgcaactcgt aacgaaggtt atattattgg tgatgttgaa
     5941 ggtaagaaag ctatcttgat tgatgatatt ttaaatacag gacgtacctt ctctgaagct
     6001 tctaaaatcg ttgaacgtga aggagctaca gaaatttatg ctgtttctag ccacggtctc
     6061 ttcgtcgagg gagctgctga gcttcttgac aatactaata ttaaagaaat tcttgtgact
     6121 gattcagtag caacaaaaga aaaaactcct aaaaatgtat gctatatcac tgctagtgag
     6181 ttaattggtg atgctatcgt acgtattcac gaaagaaaac cagtcagccc actctttgcc
     6241 tacaataaaa agaaataagg tgattctttg atttatttgg acaatgctgc aacgactcct
     6301 atgtcagcag ttgctatttc agctatgacc aaggttatgc aagaaaccca cggaaatcct
     6361 tctagtattc atggtcatgg tcgtcaagct ggcaaactct tgcgagaagc ccgtcaggaa
     6421 ctagcccagt tactaaggac aaaacctcaa catatctttt tcacttctgg tgggactgaa
     6481 ggcaataata ctaccatcat tggctactgt cttcgtcacc aagaacaagg aaaacatatc
     6541 atcacaactg ccatcgagca ccatgctgtc cttgaaacaa ttgattactt ggttcaacac
     6601 tttgggtttg aagcaaccat tatccagcca gaaaatcaag aaatcacagc ccagcaaatt
     6661 caaaaggctt tacgtgacga tacgattttg gtttctacca tgtttaccaa taatgagaca
     6721 ggaaacctac tgcccatcgc tgaaattggc caaatactca agcaacaccc tgctgcctat
     6781 catgttgatg cagttcaggc tattggtaaa atcccaattc attcagaaga attgggcatt
     6841 gattttctca ctgcttctgc ccacaaattc catggtccta agggaatcgg ttttctctac
     6901 gcatctagca tggactttga ttcctatcta catggcggag accaggaaca gaaaaaacgt
     6961 gcaggaactg aaaatctgcc tgctatcgta ggcatggttg cagccctaaa agaagaccta
     7021 gaaaaacaag aagaacattt tcaacatgta caaaatctag aaactgcctt tctggcagag
     7081 ctggagggca ttcagtatta cttgaataga ggaaaacatc atctccctta tgttctcaat
     7141 attggatttc ctggtcagaa aaatgacctc ttactccttc ggctagattt agctggaatt
     7201 tcaatctcta ctggctcagc ctgtactgca ggcgttgtcc aatccagcca tgttcttgaa
     7261 gccatgtatg gcgcaaattc agaacgcttg aaggaatccc ttcgcatcag tttgtcgcca
     7321 caaaataccg ttgaagacct acaaaccctc gcaaaaacct taaaagaaat tatcggaggt
     7381 tagccatatg gcatttgaaa aaatcattca gttaaaaaat tgtcgttacg attacactct
     7441 tagcccttct gttaaaaaat tcaccctcaa agataacacc ttttttgaaa ctaaggttgg
     7501 taactatgaa ctgactcgcc ttttggaaaa agtgccaaac agcggtgaag gcttccaact
     7561 caaaatcatc attaacaagg aagttacagg ggctaaaatc aatatcactg ataagtttgg
     7621 ccttcgtcta gttgatattt tcaaatcaga agaccaccat attcatcagg aaaaattcta
     7681 cttcctcatg gatagcttgg tagaacgtgg tgtctttaca aaatcggaaa gatagagcca
     7741 aaatgtttga actgacctat aaggactgct atcatgtaga gcgtactctc aagtatgagg
     7801 atcatgaggc tctcatgttg actttgtcag gatgtgtaac cttaccagat acactttatg
     7861 tgacttctct gacttttagg ggccaaaaag tttatcaggg tctggtcgga gacctctacc
     7921 gttttctatc tcatgcagat tttttgcatc aaaactaaga tttttcttag ttttttctta
     7981 tttttgttga ttttttcaca atgtttctat aaaatagaag aatagaaagg ttgtgatttt
     8041 gtgaaagata aacagtttgc tattccaaaa gctacagcaa aaagactctc tctctactat
     8101 cgaattttta agagatttca tgcagaaaag attgaacgtg ccaactctaa gcaaattgca
     8161 gaggctatcg gtattgattc agcgaccgta cgtcgtgatt tttcctattt tggtgaactt
     8221 ggtcgtcgtg gttttggata tgatgtcaaa aaactaatga cattttttgc cgatttgctc
     8281 aatgacaact ctattaccaa tgtcatgctg gttggtattg gaaatatggg ccatgccctt
     8341 ctccactacc gcttccacga acgtaacaag atgaagatta tcatggcctt tgacctagat
     8401 gaccatcctg aagtcggtac ccaaactcct gacgggattc ccatttacgg aatttctcag
     8461 atcaaggata aaatcaagga tgctgatgtg aagactgcta tcctaactgt tcccagcgtc
     8521 aagtcacaag aggttgctaa tctcttggtt gatgctggtg tgaaaggaat tctcagtttt
     8581 tcaccagtcc atctgcattt accaaaagac gtggtcgttc agtatgtcga tttgacaagt
     8641 gaactccaaa ccctcctcta cttcatgcga aaagaggatt agaaagcgaa aatcatttta
     8701 tgaaaaaacc agttattggg attacaggaa acgaaaaaac tcatccagat gatgacatca
     8761 tgatgagcta cgcagcaaaa ggctttgttg aaggcgttaa agatgctgga gggattccca
     8821 tcatcctacc gattggtgat caagaaatgg cctgccacta tatcagtttg attgacaagc
     8881 tcatcttgac aggtgggcaa aatgtcgatc caaaattcta tggcgaaccc aaaaccattg
     8941 atagcgatga ctatcacctt caaagagata tcttcgaact ggccctcatc aaggaagcta
     9001 ttaaacagaa aaagcccatt ttctctgtct gccgtggtac ccaactcttt aacgttgcca
     9061 tgggtggaac tttgtaccaa gatatcgaag accattggca ggattcttct gttgagtaca
     9121 caactcaacg cttggtgaca gaaccagata ccgttctcca agaaatctat ggagaaatct
     9181 ctcatatcaa ctccttccac caccagagca tcaaggactt agcaccaaat ttaaaagttg
     9241 tggctcatga tcctaaagat ggtatcattg aggctgtcat gagtacggat gatgtcgcct
     9301 ttctcggtgt ccaatggcat ccagaacttc tttttgaaaa tcgtcccaaa gataaaaaac
     9361 tctttgacta tgtcgttaat gaactttaga ttaaatctgt cttttcacga taactaaagt
     9421 aattagaatg agagacaatc aaatggtcca agagaacaat ccccatcagt tcgcaggctt
     9481 ctttaacaag tttagtgaca tgatcatcat tttggctagg cgctaccgct cctgaaggat
     9541 gattgtggac caagataaga gaagtcgcca tatgcttgat tgcatagtgc agaatctctc
     9601 gcggttcagc gatactacga gttacagaac cgataaaaat ggtctgctga tggatgattt
     9661 gattttgagt attgagatag agtgccacca ggtgctcttg ttttttatcc cctaattcct
     9721 gctgcatctt cttggccaac ttttgactgc tgagaatact ttccatttca agagtctcgt
     9781 gtttgtgaat acgatgcccc agttcaatca tagcttgtaa ttctatggcc ttaacacgcc
     9841 caataccaga caaactctgc aattcctgca gggtcatttt tttcaaatcc gttaggcttg
     9901 aaagattgtt caagactttt tgggcaattt caaaaacgct agcttgacgt gttcctgtcc
     9961 tgagtaaaat agctagcaac tcttggttac taagcgcttc aactccttcc ttggccagcc
    10021 tttctcttgg taatagtgaa tcttcttgga atgaaatact gtacataaaa atcctcctca
    10081 ctttattatt cgtgagaagg atggaaaatt agattttttt ctcaattgga gccacactgg
    10141 ctaaaagttt tttcaaacct acttctggga aattgatttt caattcctgc ctagcaccgc
    10201 tacctgaaac ttccagaaca gttccctctc cccatttctt gtggagagca atgtcaccaa
    10261 tggaccaatt tgcctcgcta gatgctgatt ttgcgccagc tgtaaattga ccaaatggaa
    10321 gaccgcttga ctggattgat tttggggcag caccgcgttt acggtcttga agagcctgag
    10381 ccaaactcat accttgacca aaggaaatac taccactgct atatgatgcc ttaaagcttg
    10441 tatttgcagg acgagccaga ccttgatact caagcaagtc tgaactgatt tcgttaataa
    10501 aacgagtcgg acggttataa ttggtacgac caaaaagcaa gcgtgagttg gcattggtca
    10561 gatagagaat tttctctgca cgcgtgatac ctacataggc tagacggcgc tcttcttcta
    10621 attcatctgt atcttcagtc gcacgactaa gtggaaagac attttcttcc atcccaatca
    10681 aaaagacaac tggaaattcg agacctttgg cagcatgcag ggtcatcaag gtcacttctg
    10741 atgtctcctg actacctgaa tctgtgtcgg caatcaaagc caagtcattt aagaaacgac
    10801 tcagtttgtc cagaccagtt tcctcttctg tcacatcagt ggtgtcatca aagttcttcg
    10861 taacagaaag aaactcttcg atattttcaa cccgtgcctt gctttctaga gtcgcttggg
    10921 cgttaagaat atcgacataa cctgtttttt ctaggacgga ctcaaccaac tctgtaatgc
    10981 ttaagtggtc tagctgctcc cgcaaatcaa gcatcatatt ggcaaaatcc cagatagatt
    11041 gggctgcctt acccttgata ccagacaaca taatattagc agaagcatcc agcatagaca
    11101 tattttgcaa atttgcaaaa tcacggattt tctcaactgt acctggacca attccacgtt
    11161 taggctcgtt gataatacgc tcaaaactaa tattgtcact caaattagca ataaggttga
    11221 gataagcaat aatatcgcga atttccttac ggctgtagaa tttggttccg ccaaccatgg
    11281 tataaggaat gttagacttg agcagggctt cctcaattgt acgggactgg gcattagtcc
    11341 gatagagaac tgcaaaatcc ttatgaagga agttttgact gcgactaagt tcatcgatgg
    11401 ttctggctac aaatacagcc tcatccagct catcatcggc acgatagtaa acgatttgct
    11461 ccccatcagc gttttgagtc cagagatttt taggacggcg atttttattg tttttaataa
    11521 cctcgttggc cgcttggaga atggttttgg ttgagcggta attttcctcc aacaaaacaa
    11581 ccttggcttt ggggtaatcc ttttcaaagt ccaagatatt ctgcatatca gcaccacgcc
    11641 aaccgtagat agactggtcc gcatccccaa ccacacagat atttttaaaa cgggaagcca
    11701 agagtttgac caattggtac tgagcgtggt tggtatcttg gtactcatca acgtggatgt
    11761 attggaattt ttgctggtag taggttaaaa catcaggatt ttgatcaaag agacgcaagg
    11821 tcagcataat caaatcatca aagtcaacgg attcagactg acgaagttct ttttgatagg
    11881 ctgtataaca ctgggccaca atttgcgtat acatatcgcc agcttgggca gcataagcaa
    11941 catcatcaat caaatcattc ttagcattgg aaatggtccc caaaatagtt cgttcattcc
    12001 attttttagg atccaagttc aactgtttga gaatacgttt catgagcgtt cgctgttcac
    12061 caggatccac aattgtaaaa ttacgattgt agccaatatg gtccgcatcg cgacgcaaaa
    12121 tacgcacaca catggagtgg aaggtcgcaa tcagacagtt ctgagtagct ggattgagac
    12181 tataagcacg ctctttcatc tcacgcgcag ccttgttggt aaaggtaatg gccaagatat
    12241 tccaaggatt gaccagcttt tcatcaatca aataagcgat acggtgggtt aaaacacgag
    12301 tctttccaga accagcccct gccatgatta gcaagggacc ttctgtcgtt tgcaccgcct
    12361 cagcctgacg gtcattcatt ccatttaata atgcgttcat cttctcttcc ttactcttga
    12421 agtcaatatt tctattatat cagaaatcag ggaaaataga aactttacgg ggagtagcaa
    12481 aatatagtgg attgaaacta gaatactaca ctgtgggttt ctaaaacact cgacttttca
    12541 cccaattttt tcataaacta gctcaatacc tcaatagact tcctgcaaaa ctagaatcct
    12601 agttcatgat tgataatacc agcaataaaa ttcattcgta atccgaagcg tttacgatga
    12661 tttcgataag ttgttgaaaa cattttaaac gtttttactt tggcaaagat gttctcaacc
    12721 ttgcttctct ccttagatag cgcatggtta taagccttat cttcaactgt tagcggcttg
    12781 agtttgctgg atttacgtgg agtttgtgct tgaggatata ttttcatgag cccttgataa
    12841 ccactgtcag ccaagatttt accagcttgt ccgatatttc tgcgactcat tttgaacaac
    12901 ttcatatcat gacaatagtt cacagtgata tccaaagaaa caattcttcc ttgacttgtg
    12961 acaatcgctt gagccttcat agcgtgaaat ttctttttac cagaataatt ggccagttga
    13021 tttttttagg gcgattggtt tttacttccg tcgcatcaat cattaccgtg tcctcagaac
    13081 tgagaggagt tcttgaaatc gtaaaaccac tttgaacaag agttacttca acccattggc
    13141 tccgacggat taagttgctt tcgtgaatac caagatcagc cgcaatttgt tcataagttc
    13201 gatattctcg cacatattga agagtggcca taagaaggtc ttctaggctt aatttaggtt
    13261 ttcttccacc ttttgcatgt ttaagttgat aagctgtttt taatacagct aacatctctt
    13321 caaaagtggt acgctgaaca tcaacaagac gcttaaatcg tgcatcagtt agttgtttac
    13381 ttgcttcatc attcatagaa ctactatacc atgttttgtt tcgcaggaag tataatataa
    13441 aaaaataaat ttaagattgg caatacgaac gttaaacaga attccatttc tctttttaga
    13501 atcaaaacga caatattgtg gaatctctac aggaacaata gactgcgaca ctaaaatatc
    13561 ctcccttagt tttactttac taatagtata taggaggaga gccctgaatc ctagaccctt
    13621 tgttatgatg cgcttacaaa cagagttgga aaaaatctta aaagcagaaa aacgcatgat
    13681 atcagcccct aacacttgat acaatgcgtt ttattatgaa aagatctact ggatttttta
    13741 tcaaaataaa cttccagtag tcttttcact ttttattaat aagttccttc ttcaccttgg
    13801 ctagtcaaga taacaggtcc atctttcgta atgacaaatt ggtgttcata ctgacatgac
    13861 aatccaccgt caatggtctt atgcgcccaa ccagttttca tatctgtatc aatttcccaa
    13921 tcgcctgtat tgatcattgg ttcaatggtt aagaccattc cttcacgaag acggagtcca
    13981 cgacctgcaa taccatagtt aggaaccatt ggttcttcgt gcatagttgg gccaacacca
    14041 tgaccaacca aatcacgcac tacaccgtaa ccacgacttt cagcgtattc ttgaatagcc
    14101 gcaccgatat caccgatacg atttccaaca acagcttgct caataccctt gtacatagct
    14161 tctttggtta catccatcaa gtttttgact tcttcggacg gtgtaccaac agcataagcc
    14221 caacatgagt ctgctaaacc accagaatag ctctgagtat attttttcat ttgttcaaca
    14281 ttgttgaagt ttaattttga gacattcagg tcagatttag caatgggacc tcccaaaacc
    14341 atatcaactt tgagcaaatc accatctttc aagatataat gacgagggaa agcgtgagcc
    14401 acttcatcgt taagagagca acaggtagca taaggatagt ccatcatggc accgtcaacc
    14461 ccaatctgaa gtggaaggaa attttcttct ttacaacgac ggcggacata ttcttcaact
    14521 tcccacatat ctacgcctgg cttaatcaaa tcacgtaagc ctatatgaat acttgctaga
    14581 aaatcaccag ccttgtccat agcttcgatt tcacgagctg attttaatgt tatcatcttt
    14641 tctcctagtt tctaattaat tttaacagtc acatttgctt ttgaaacaat ctggtgacca
    14701 tgataaatat cgtaatcaat tatagctgac cgtctcgtat gatgaataat ccgtgcctga
    14761 atgcgcaata tatcatctat ctgaacagcc tgcaaaaagt agatcagcat ctgctcgata
    14821 atgagattgc gaccactatt aacaactaaa tcttgggtca tgtgggtcag aatttctgcc
    14881 aatacaccat tagccaaaac tccatttttt tctagcataa agggttccac tgtaatgact
    14941 acttcatcat ggtgataaga gagcttttgt ccaatctgct cagaaaaagt tggtagagcc
    15001 gaaacttggg aacggctcat cttctccatg acatctcgtc gcgtcacaac gccaagcaaa
    15061 gtttgattgc ttcgaacaac tggtaccatt tcaaagtctt ctgcgatcat ccgttgactc
    15121 acattggcaa tatttgtcga taatccaacc aaaaatagac tacgagacat aaccttatca
    15181 attgtcgtgc ttggtgattt atcaccagcg tctctcatgg ttacaacgcc aacaacgacc
    15241 tgatgttgat tgataacagg gaaacggctg ctacgattct tacgaaccaa gtccaaataa
    15301 tctttaactg tatctgtctc tctcagaaaa ccatactcat gactagggcg ataaagtttc
    15361 tcaactgtca gaatatcagt cttgatttgg acatttgaca aggctttatt gatcatggtc
    15421 gcgacggtaa aggtatcatg cttacttctt agaacaggaa tccctttttg attggccagt
    15481 ttaagcacat catcatgaac ctgaaatccc cctgtaacca gaactgcatt ttcattttcc
    15541 aaggctagca actgaatacg ggttcggtct ccgacaatca agagcccccc atcatgaagg
    15601 taagacaaga tattttgttc agtcatggca ccaattgaaa acttactaaa ttctctctct
    15661 aaaccttctt gcccagccag aacctcagaa gaagtcactt ctgcaatttc agcaaacgtt
    15721 aatctctcta tagcaacttt ctgggattta acacgaattg ttccacttct aggacgggtc
    15781 tccacaattc cacggttttc agcttcttta atagcccgat aggctgttcc atcactaact
    15841 cctagatgat tcgaaatgct acgaacactg acccttttac ctactggtaa ttcctccaaa
    15901 tagcttagaa tttcctgatg cttactcatt gaactctcct tttacatacc gaaattcaag
    15961 ataatcccgc atttttcttg tgtaacgatc acttccctta aactgacgga acaaactaaa
    16021 tccagactta agagcaactc tttggctagc ttcattttca aggtgggtaa tgatagataa
    16081 ttgttttaag ccaaattcct caaaagaaag ctgacaaatt tttctaacaa cctctgtcat
    16141 aaatccttgc gaccaagcat cttttctcaa aaaatagcca agctcagctt cttttttgat
    16201 ttcatctaac ttctcaaatt taatagaacc aatcatttgt tgatttttct ggtcacaaat
    16261 tgcccacact cccaaagggg acttcataaa gtaattggcc agtgcatatt gactttcttc
    16321 cagacttgcc tgcgttggga aaataaattg aagattttct ggatttgaag ctatctcgcg
    16381 gaagtcctga ctatcactaa aaaagaaagg acgcaaatac aagcgatccg tttcaaaaaa
    16441 agaaaacatt gctaatttgg tccaaatatt cataaacacc tctacggttt aatcctcaac
    16501 aagtctaata tccgctccta aattacgtaa tttttcgata atatcagaat aaccacgtaa
    16561 gataaactcg atattggtaa tttcagtttt accttcagcc ataagcccag caatgactag
    16621 tgcagcccca gctcttaagt cggtcgcttt aacactggcc ccacgtaaat cacgtccacc
    16681 cgtgtacaaa atatgaccat ttgttgtcga aatatccgca tccatctttg ctagttcaaa
    16741 aacatgattt acacgttttt cgtaaatcgt atcgacaatt gtaccacgac cattcgctct
    16801 tagtaaaaga ggggtaagcg gttgttgcaa atcagttgca aagcctgggt aaggagctgt
    16861 cttaatattg attgctttca aattagactg ttcctcgaca aaaatgctgt cttcagatac
    16921 agtcattctc actcccattt cttccaactt agcaataaac ccttccaggt gttcgtaaag
    16981 aacattattt atacgaattc ctttaccaac tgcagcagct aaagatatat atgttccagc
    17041 ttcaatgcgg tctggaatca cctgatgacg tgtcccatgt aatctttcaa caccatcaat
    17101 aatgatgata ttagttcctg ccccacggat atgggcaccc atattattca agagagtagc
    17161 tacatcaata atctcaggtt cacgggctgc attttcaata atagtacgac catttgcttt
    17221 aaccgcagca atcatcgtat taatcgttgc tcccacacta accgtatcca tgtaaatact
    17281 tgcaccatga agtcctgtat ctttagcaga taacttcatg ttatctccct cgtagctagc
    17341 agtggcaccc atagcttcaa acgccttaag gtgtaagtca atcggacgag gaccaagatc
    17401 acatcctccc ggtagaccaa ctgtcgcttc accaaaacgg cctaagaggc tcccataaaa
    17461 atagtaagat gcacgaagac tgttaatttt accataaggc attggaatat tttgaacacc
    17521 tcttggatca atctccaaga catcgtcata acgcttaaca gtagctccca tcaattccat
    17581 gatttcgaca agactggcta catccgaaat atctggaaca caatccaaag tcaccacatc
    17641 atcagccaag ataatagctg gaattaaggc cacaacacta tttttagcac cactaatagt
    17701 aatttcacct tgcagtggta atccaccatt gataacaatt tttctcattc taagttttca
    17761 atactctttc aagatttcta ataaggtctt caaaataaag tatatcataa atttatcctt
    17821 ttttccatcc ttttcaattt tattggataa atcagagttg acgagttagt aactgaatta
    17881 ctaatactca ataaaaatca aaga
//
LOCUS       DAVBNZ010000046        16835 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000046 DAVBNZ010000000
VERSION     DAVBNZ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16835
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.046"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            49..537
                     /locus_tag="VQ860_001586"
     CDS             49..537
                     /locus_tag="VQ860_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET3119986.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            534..1721
                     /locus_tag="VQ860_001587"
     CDS             534..1721
                     /locus_tag="VQ860_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3119987.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            1714..2079
                     /locus_tag="VQ860_001588"
     CDS             1714..2079
                     /locus_tag="VQ860_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3119988.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKMAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            2095..3441
                     /gene="asnS"
                     /locus_tag="VQ860_001589"
     CDS             2095..3441
                     /gene="asnS"
                     /locus_tag="VQ860_001589"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET3119989.1"
                     /translation="MMTKRVTIIDVKDYIGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            3594..3884
                     /locus_tag="VQ860_001590"
     CDS             3594..3884
                     /locus_tag="VQ860_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET3119990.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            3896..4366
                     /gene="ssbA"
                     /locus_tag="VQ860_001591"
     CDS             3896..4366
                     /gene="ssbA"
                     /locus_tag="VQ860_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET3119991.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            4398..4637
                     /locus_tag="VQ860_001592"
     CDS             4398..4637
                     /locus_tag="VQ860_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET3119992.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            4932..6332
                     /locus_tag="VQ860_001593"
     CDS             4932..6332
                     /locus_tag="VQ860_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET3119993.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGLLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            6334..6693
                     /locus_tag="VQ860_001594"
     CDS             6334..6693
                     /locus_tag="VQ860_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET3119994.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVLDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            6747..7496
                     /locus_tag="VQ860_001595"
     CDS             6747..7496
                     /locus_tag="VQ860_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET3119995.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            7486..7785
                     /locus_tag="VQ860_001596"
     CDS             7486..7785
                     /locus_tag="VQ860_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET3119996.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            7856..8791
                     /locus_tag="VQ860_001597"
     CDS             7856..8791
                     /locus_tag="VQ860_001597"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET3119997.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            8877..9389
                     /locus_tag="VQ860_001598"
     CDS             8877..9389
                     /locus_tag="VQ860_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET3119998.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            9426..10021
                     /locus_tag="VQ860_001599"
                     /pseudo
     CDS             9426..10021
                     /locus_tag="VQ860_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            10122..10316
                     /locus_tag="VQ860_001600"
     CDS             10122..10316
                     /locus_tag="VQ860_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3119999.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(10362..11807)
                     /locus_tag="VQ860_001601"
     CDS             complement(10362..11807)
                     /locus_tag="VQ860_001601"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET3120000.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HSSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            11913..13535
                     /locus_tag="VQ860_001602"
     CDS             11913..13535
                     /locus_tag="VQ860_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3120001.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALVLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            13738..15696
                     /locus_tag="VQ860_001603"
     CDS             13738..15696
                     /locus_tag="VQ860_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3120002.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVVSKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGIESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            15868..16428
                     /locus_tag="VQ860_001604"
     CDS             15868..16428
                     /locus_tag="VQ860_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3120003.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTG"
     gene            16429..16803
                     /locus_tag="VQ860_001605"
     CDS             16429..16803
                     /locus_tag="VQ860_001605"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120004.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALENLLAVPKEKFE"
BASE COUNT         4991 a         3093 c         3752 g         4999 t
ORIGIN      
        1 ttcttatatt cacttgtaat aaagcttaat agatggtaaa atagacgagt gaaaaaaaga
       61 caaaacaaag caaaaaataa tctactgtgg cagtatggtc tagggatgac gattttgttt
      121 gtggttatca gtgcttcctt tctgtatatg gtttctctta gcatgaaacc ctatcaaaca
      181 gctaaaagtg aaggagaaaa attagctcag cagtatgcag gattagagca ggccgatcag
      241 gttgatttat acaatggctt ggaatcttat tacagcgttc ttggtcgtaa taaacagcaa
      301 gaagcacttg ctgttctgat tggaaaagat gatcataaga tttacgttta tcagctaaat
      361 cagggtgttt cacaagaaaa agcagaaacg gtttctaagg aaaagggagc tggcgaaatt
      421 gacaagatta tctttggtcg ttatcaagat aagccaatct gggaagtcaa gtcaggatct
      481 gatttttatc tagtagattt tgaaacagga gcattggtca acaaggaggg cctatgaaat
      541 tatccaaccg tgttttagaa atggaagaaa gtgtgacttt ggctgctgga gcccgtgcca
      601 aagcactgaa ggctgagggc agagatattt tgtctctaac cttgggtgag ccagatttca
      661 ctactcccaa aaatatccaa gatgccgcca ttgcatcgat tcgagatggg cgtgcttctt
      721 tttatacagt aacctcaggt ctgccagagc ttaaggcggc ggtcaatagc tactttgagc
      781 gcttttacgg ctattctgta gcgtcaaatc aagtgacagt cgctgcggga gccaaatatt
      841 ctctctatac cttctttatg gctgtggtca atccaggtga tgaagtcatc atcccaaccc
      901 catactgggt tagctatgga gatcaggtca agatggcaga aggcgttccc gtctttgttt
      961 ctactaagga agacaatcac tttaaggtga ccgtagatca gttagaagca gctcgcactg
     1021 acaagaccaa ggttttggtg ctgaattcgc catctaatcc cacaggtatg atttacaccc
     1081 gtgaggaact cttggcaatt ggaaactggg ctgtagaaaa tgatattctc atcctagcag
     1141 atgatatcta tggccgcttg gtttataatg gtcatgagtt cacaccgatt tctagcctat
     1201 cggaagcgat tcgcaagcaa acagtggtca tcaatggtgt gtctaaaacc tatgccatga
     1261 ctggttggcg gattggttat gccgttggag aagcagacat tatcgctgcc atgtccaaga
     1321 ttgcaggtca aacaacttcg aatccgtcag cagtagccca atatgcagca gttgaggctc
     1381 tatcaggtga gcaagatact gtagaaagca tgcgtcaggc ctttgaggaa cgtcttaata
     1441 ctatctatcc cctccttgca gaggtgccag gatttgaagt ggtcaaaccg caaggggcct
     1501 tctatctctt cccaaatgtc aaaaaggcca tggagatgaa aggctacacg gatgtgacag
     1561 actttacaac tgctatctta gaagaagccg aagtggcctt ggtaacagga gctggatttg
     1621 gagcaccaga aaatgtccgc ctcagctatg cgacagacct agacacgctt aaagaagcag
     1681 tcgaacgctt gaaagcattt atgggtagtg agaatgattg atcattttga gattaaggta
     1741 aaggatttac aaatttcaga aggattttat aggagttttc tcgctccttt ggactataaa
     1801 atggctttta agactagttc tctaattagt tttctatccc cgaacagccc tcatcctggt
     1861 ggtgattttt ggctgactca gggaacacaa gatcctgttc attttgcttt tttagcagaa
     1921 aataaggaag aagttcaggc ttgttatgag gctggcttag aggcaggtgg gcgagacaat
     1981 ggggttcctg gttatcgaag tgagcatccg atttattatg ctgcttttat gattgacctg
     2041 gatgggaaca atatagaggt ggtttgccat aaagaataaa aaagaaaagg aaaaataatg
     2101 acaaaacgtg taacgattat tgatgtaaaa gactatattg gtcaagaagt gacgattggc
     2161 gcttgggttg ccaacaaatc aggaaaaggg aaaatcgctt tcttacaatt gcgtgatgga
     2221 acagccttct ttcaaggtgt ggcttttaaa ccaaactttg tcgaaaaatt tggtgaagaa
     2281 gtgggacttg agaagtttga tgttatcaaa cgcttgagcc aagaaacgtc tgtttatgtg
     2341 acaggtattg tcaaagagga cgaacgttct aaatttggct atgagttgga catcacagac
     2401 atcgaagtga tcggtgaatc tcaagactac ccaatcacac caaaagaaca cggaacagac
     2461 tttttgatgg ataaccgtca cttgtggcta cgctctcgta agcaagtagc tgtgttgcaa
     2521 atccgtaacg ctattatcta tgcaacttat gagttctttg acaagaacgg ttttatgaag
     2581 tttgacagcc caattctttc aggaaatgcg gcagaagatt ctacagaact ctttgaaact
     2641 gactacttcg gaacgccagc ctacttgagc caatcaggtc aactttacct agaagcaggg
     2701 gctatggctc ttggtcgtgt ctttgacttt ggtccagttt tccgtgctga aaaatcaaaa
     2761 acacgccgtc acttgactga gttctggatg atggatgctg agtactcata cttgacacat
     2821 gatgagtcgc ttgacttgca agaagcttat gtgaaagctc ttctacaagg tgttcttgac
     2881 cgcgcgcctc aagccttgga aaccttggaa cgtgatacag aactcttgaa acgctacatt
     2941 gcagagccat tcaaacgtat cacttacgat caagccattg acctcttgca agagcatgaa
     3001 aatgatgaag atgctgacta cgagcatctt gagcatggtg atgactttgg gtcaccacac
     3061 gaaacttgga tttcaaacca ctttggtgtg ccaacatttg tcatgaacta tccagcagcc
     3121 atcaaggctt tctacatgaa accagttcct ggaaatccag agcgcgtgct ttgtgcagac
     3181 ttgcttgctc cagaaggcta tggagaaatt atcggtgggt ctatgcgtga ggaagattac
     3241 gatgcccttg tcgctaagat ggatgaactt ggcatggatc gtacagaata tgaattctac
     3301 cttgaccttc gtaaatacgg tacagttcca cacggaggat ttggtatcgg tatcgaacgt
     3361 atggtaacct tcgcagcagg aacaaaacat atccgtgaag ctattccatt cccacgtatg
     3421 ttgcaccgta tcaaaccata agaacaggaa aacgcccatg tggcgttttt tcgaattcta
     3481 gtgtttttac ttgcgtaaaa aaattttttc tagtataata gtttattgtg agcgaacctc
     3541 acttacccct tgcaaagtct tggggtcatt agaccaaaag gaggaacata tcaatggcta
     3601 aatacgaaat tctttatatc attcgtccaa acattgaaga agaagctaaa aacgctttgg
     3661 tagcacgttt tgactctatt ttgactgaca acggtgcaac tgttgttgaa tcaaaaactt
     3721 gggaaaaacg tcgtcttgca tacgaaatcc aagatttccg tgaaggactt taccacatcg
     3781 ttaacgttga agcaaatgac gatgcagctc ttaaagagtt tgaccgtctt tcaaaaatca
     3841 acgctgacat tcttcgtcac atgatcgtca aaattgacgc gtaagaaggt aaactatgat
     3901 taacaatgtt gtacttgtag ggcgtatgac acgtgacgct gagttgcgtt ataccccatc
     3961 aaatgtagca gttgcgactt ttactcttgc agtaaaccgt acatttaaga gtcaaaatgg
     4021 tgaacgtgag gctgatttta tcaatgtcgt tatgtggcgc caacaggctg aaaatcttgc
     4081 taactgggct aaaaaaggct cacttatcgg ggtgacaggt cgtatccaga ctcgtagtta
     4141 cgataaccag caaggacaac gtgtctacgt gacagaggtc gtggctgaga atttccaaat
     4201 gttggaaagc cgtagtgtgc gtgagggtca cacaggtgga gcttactctg caccaactgc
     4261 aaactattca gcacctacaa attcagtacc agacttttca cgtaatgaaa atccatttgg
     4321 agcaacaaac ccattggata tttcagatga tgatttacca ttctaatgga caactaaact
     4381 tataaaggag aaaaaacatg gctcaacaac gtcgtggcgg attcaaacgc cgtaaaaaag
     4441 ttgattacat cgcagcaaac aaaattgaat atgttgatta caaagatact gagcttctta
     4501 gccgtttcgt ttcagaacgt gggaaaatcc ttcctcgtcg tgtaacagga acttcagcta
     4561 aaaaccaacg taaagtaaca acagctatca aacgcgctcg cgtaatggct ttgatgcctt
     4621 tcgtaaacga agattaaaga aaagacccgg ttgggtctct ttttcatgag cttgaaaaca
     4681 agaaagcgaa ttaagacccc aacgggtctt ttttcacaag ctttgaaatg agagagcgag
     4741 ttaggctcag tggcttcctt tttacgagtt tgaaaacaag agaacacatt aaaagcacga
     4801 tggagctttt tcataaatat gtctcttttc tcatccaaga aattaaaata aaaatgataa
     4861 actttttgaa aataggggat ttgcctactt tatgatataa tggaaagagt tagattgaaa
     4921 gaggtagtga gatggacgcg aaattaagat acaaggcaaa gaagatcaag attgtctttt
     4981 ttgatattga tgatacattg cggaattcaa agacagggtt tattccaact acaattccca
     5041 ctgtttttaa acagttgcgt gaaaaaggaa ttttaacagg aatcgcctct ggacgtggca
     5101 tttttggtgt tgttccagag attcgtgatc tcaagcctga cttttttgta actttgaatg
     5161 gggcttatat cgaagataaa aaaggtcagg tcatttatca gcatcagatt gaaaagtcag
     5221 atgttgagga gtatatctct tgggctaagc aagaaggaat tgagtatggc ttggttggga
     5281 gtcatgatgc caagttgtcg actcgcaccg atatgatgag tgaagctatc aatccaattt
     5341 atcccgactt agatgtagat cccgatttcc atgaaaaaga agatatctat cagatgtgga
     5401 cttttgaaga taagggagat gacttgcact tgcctgacag tctctcagac aaacttcgca
     5461 tggttcgttg gcatcaacat tcgtctgata ttgtgccgat ttcaggctcc aaagcgacgg
     5521 gggtggaaaa ggttgtggaa caccttggct tgaaaccaga gaaggtcatg gtttttggag
     5581 atggtctcaa tgacttggaa ctctttgatt atgctggaat cagcgttgcc atgggaattt
     5641 ctcatgataa aatcaaagaa aaagcagatt atattacaaa aacattagaa gaagatggca
     5701 tttttgatgc cttagaagta tttggtatgg tagaaaaaga attgcatttt ccacaagtag
     5761 acattgaaac agtagaaggt cttcttgcga ctattaagac caatcacgga gacttacgta
     5821 tcaagctttt ccctgaacat gctcctaaaa cagtggctaa ctttgtatct ctttcaaaag
     5881 atggctacta tgatggtgtc attttccacc gtattatcaa ggactttatg atccaaggtg
     5941 gagacccaac tggaactggt atgggtggcg agtcaatcta cggcgaatct tttgaggatg
     6001 aattctcaga agagctttac aatatccgtg gtgctctttc catggcaaat gctggtccaa
     6061 ataccaacgg cagccagttc tttatcgtgc aaaaccaaca cctaccttat tcgaagaaag
     6121 aaattactcg tggtggttgg ccagaaccga ttgcagaaat ctatgccaat caaggtggga
     6181 cacctcacct agaccgccgt cacacggttt ttggtcagtt agctgatgaa gcatcttacg
     6241 ctgtcttgga tgccattgct gctgttgaga caggagctat ggacaagcca gttgaagatg
     6301 ttgtaattga aactattgaa atcgaggact aagatgaaaa tcggtgataa gctaaagggg
     6361 cgtattacag ggattcagcc ctacggtgcc tttgttgagt tagagacggg tgatacgggg
     6421 ctgattcaca tttcagaaat tcggacagga tttattgaaa atattcatga aaccttgaaa
     6481 gtcgatgaag aggttcaagt tcaggtactg gatttagatg aatttacggg gaaagccagt
     6541 ctttctatcc gcactttgga ggaagaaaag taccagtttc ctagacggag acgcttttca
     6601 agtgaccgct ttaactacgg ttttgctccc tttcgacgaa tgctaccaat ctggactgga
     6661 gaagctctgc accatttaaa aaagaagaag tagtttagag ttttatattt tttgtaatgt
     6721 taatataaat ttattataat aggaccatgg aagaagaaca attattaaaa tcaggagagc
     6781 gcattaacca gctcttttcg acagatatca aaatcattca aaatagagag gtttttagct
     6841 attcggtgga tagtgttctc ttatcacgat ttccacgttt tcctaagaag gggttgattg
     6901 tggatttctg tgctgggaat ggagcagtgg ggctttttgc tagcactcgt actcaagcac
     6961 agatattgtc tgttgagatt caggagcgtt tggcggatat ggctgaacgc tctgtccgtt
     7021 tgaatggatt agaggagcaa atgcaggtca tctgcgatga tttgaaaaat atgcctgctc
     7081 acattcaggg gagtaaggta gatatgattt tgtgtaatcc accctatttc aaggtggatc
     7141 cttattctaa tctgaacgag agtgaacatt atctcttggc tcgacacgaa atcacgacta
     7201 atttggaaga aatctgtcgt agtgcccaga gtattctcaa gtctaatggg cgtttggcca
     7261 tggttcatcg tcctgatcga cttctggata ttttggatac gttaaaacga cataatctag
     7321 cccctaagcg cctgcagttt gtttatccaa aaagagaaaa ggaagccaat atgcttttga
     7381 ttgaggcgat caaggatggc tcaacaagtg gctttaaggt cttacctcct ttgattgtcc
     7441 acaatgatga tggctcttat acgcccgaaa tcgaagagat ttattatgga tcataaggct
     7501 tatatgtacg ttctggagtg tcgtgatgga tcctactata taggctatac gactgatgtg
     7561 agaagacgcc tcgctatcca caatagtggg aagggagcca aatatacacg agcacgcttg
     7621 ccagtcaaac ttatctatgc tcaaggtttt gccagtaagg aagaagccat gtcggctgaa
     7681 gctcttctca agcgtaagaa gaggccacag aaggaagaat ttttatctga aaatcaagat
     7741 agaaatttac tcagttattt tgaagaatcg tggggagtcc tttgactcct cttacctttg
     7801 tcaaaaagcg aaaaaaatgc tacaataaag aaaataaaca aaatgaggta ttatcatgtc
     7861 caagattcta gtatttggtc accaaaatcc agactcagat gccatcgggt catctgtagc
     7921 ttttgcctac cttgcaaaag aagcttacgg tttggatacg gaagctgttg cccttggaac
     7981 tccaaatgaa gaaacagcct ttgtcttgaa ctattttggt gtggaagcac cacgtgttat
     8041 cacttctgcc aaagcagagg gggcagagca agttatcttg actgaccaca atgaattcca
     8101 acaatctgta tcagatatcg ctgaagtaga agtttacggt gttgtagacc accaccgtgt
     8161 ggctaacttt gaaactgcaa gcccacttta catgcgtttg gagccagttg gatcagcgtc
     8221 ttcaatcgtt taccgtatgt tcaaagaaca tggtgtagct gtgcctaaag agattgcagg
     8281 tttgatgctt tcaggtttga tttcagatac ccttcttttg aaatcaccaa caacacaccc
     8341 aacagataaa atcattgctc ctgaattggc tgaattggct ggtgtgaact tggaagaata
     8401 tggtttggca atgttgaaag ctggtaccaa cttggctagc aaatctgctg aagaattgat
     8461 tgatatcgat gctaagactt ttgaactcaa cggaaataat gtccgtgttg cccaagtgaa
     8521 cacagttgac atcgctgaag ttttggaacg ccaagcagaa attgaagctg caatgcaagc
     8581 tgcaaacgaa tcaaacggct actctgactt tgtcttgatg attacagata tcgtcaactc
     8641 aaactcagaa atcttggctc ttggtgccaa tatggacaag gtcgaagcgg ctttcaactt
     8701 caaacttgaa aacaatcatg ccttccttgc tggtgccgtt tcacgtaaga aacaagtggt
     8761 acctcaattg actgaaagct ttaatgcgta agattttggg tgtcagctca aaatcggaaa
     8821 gtctagtttg ccttatatcg aaaggagttt cggctccttt tttctaggag tgaagtatgt
     8881 tagaaaatgg cgatttgatt tttgtgagag atgggtcaga catgggacag gccatccaga
     8941 cttccacagg taactatagc catgttgcca tttatttgga tgggatgatt tatcatgcta
     9001 gtggacaggc tggtgttgtc tgtcaagaac cggcagactt ctttgagtcc aatcatttgt
     9061 acgacctcta tgtttaccca gaaatggata tccagtcggt gaaggaaaga gcttgcagac
     9121 atcttggagc accctacaat gcttctttct atccagatgc agctggtttc tactgctccc
     9181 agtatatagc agaaatccta cctatttttg aaactattcc tatgaaattt ggagatgggg
     9241 aacaggagat tagtgatttt tggagggagt attacataga actaggtctg cctgttcctc
     9301 tgaaccaagc tgggaccaat cctagtcagt tggcagcatc gcctctgtta caatgtaaag
     9361 aaaggaatct tcatgattca gatttttaat ccatctcgtt tgacgagaca gccatttttg
     9421 gagaattgat ccgctatctg gaccagtatg aggatgtgat tctacgggaa attaaggctc
     9481 aatttccaga tgttgcagtt gataaactca tggaagagta tataaaggca agcttgattc
     9541 tacgtgaaaa taagcgctat tacctcaatt ttcctacgct tgaatcactt gatagtcttg
     9601 aactggatca agagattttt gtcagagaag ctagtccggt ctatcaagcc ttgttggagc
     9661 agagttttga gacggaattg cgcaatcaaa tcaatgcagc tattttagtt gaaagacgga
     9721 ctttgcgcgc attaaaatga ccctgtccaa ttatttttac aaggtcaaac agcagtatcc
     9781 tttgacagaa aaacagcagg agctctatga cattttagga gatgttaatc ctgagtatgc
     9841 actcaagtat atgacggctt ttttgttgaa atttctcaaa aaagaccagc ttatgcagaa
     9901 atgccgtgat atctttgtgg acagtttggt tgtcttaggc tatattgtgc aaaatgaaga
     9961 tagaaagtat gagttggcta tcgattttga taaggagaga ttaactttct acttagcgtg
    10021 atttcttgtt tctgagcaca ttgtttgact ttccttagta ttcggtataa actatatgta
    10081 accggtaaca catatcggaa taaactaaag gagacaatca tatgtcactt gaaaacaaat
    10141 tggaacaagc aacaggcgct gtcaaagaag gttttggtaa agttactgga gacagcaaga
    10201 cagaacttga aggagctgtt gaaaaaacag ttgctaaggc aaaagacgtt gtagaagacg
    10261 caaaaggtgc tgtagaaggt gccgttgaag gtttgaaaaa cgtttttact aaataatagg
    10321 aaaaaatcaa gggtttcatt ttcccttgat tttttctatt cttataaata attttctgcg
    10381 acggctgtat ctcctgggta ggattctttc ttgccctgga tgatttggta acaatcggct
    10441 cccttacccg caataataac tgcatctaat tcgtgatttg tgatagccat tgccgccttg
    10501 atggcttctt ggcgatccgc aatcttttca acaggatgat tgatgtagct actaatttca
    10561 tctgcaatgg ccattgggtc ttcatagtta gggtcatcag cagtcagaaa gacttgaatc
    10621 tcagggtgtt gattgaggag gaggccaaag tccttacgac gactttctcc cttgtttcct
    10681 gttgatccca gaaccagagc aatctttccg gtttgatgag tttcaaccac attgatgagt
    10741 tttttcagac tatccccatt gtgggcatag tcgatgaaga ccttggctcc atttttctga
    10801 gtgaggactt ccatacgacc aggaacgcgg gttgcagcga tgcctttttt gatgtcctca
    10861 agacttgctc cgagacggag acaagcaagt ccagcagcaa ctgcattttc ttggttgaag
    10921 ttgccaatga gttggatatc ataatctcca gcgagtttac ccgtagctga aaagctaaag
    10981 gctttggaat tctcgatttg gttatcaaat tggctaccat agaaatcatg gtcttgatct
    11041 tcaacctgtt ctttcaagac tgagaagtgg tccatgtcac tgttaatgat gactgctcgg
    11101 ctattttcca tcaagagacg cttgtggtag aaatagtctt caaagctaga gtgttcaatc
    11161 gggccgatat ggtcaggagt gatgttaaga aagactccta catcaaaggt cagtccatag
    11221 actcgatgga ctagataggc ttgactggag acttccatga tgaggtgggt acggtcattt
    11281 tgcacagcct gattcatcat gtcaaagagg tcaatactct caggggttgt caacgctgac
    11341 ttaaaaaaag tctcgccatc aagagttgtg ttcatggtcg acaacatagc aggtctatgc
    11401 ccttgagata agatgttata ggcgaaatag gttgctgttg tcttaccctt agtaccagta
    11461 aaggcaagga gtttgagttt ctcttgtgga ttaccataga actccatggc aatcaaactc
    11521 atggctttct ttatatcgtt cacaatgatg acagggatat cgacttcgta gtccttttca
    11581 gctacatacc aagctaaacc ttgtgttata gcagaaagaa ggtattcttt tttaaaggca
    11641 gcgccttttg caaaaaaaag agtgtcttct gttacttttc ggctgtcgta gctgatgcta
    11701 tcaaaaataa ctttgctgta gttgtagtgg taatgacctt ggtcaataat ttcgcgaaaa
    11761 aggccatctt tctttaaaat atctaatacg gtttcaatct taatcatact ttctattgta
    11821 aaccgaaagt cgtaaattta caagtaacaa ggaaaagttt ataatggaag ataaggagtt
    11881 tttcctagtt atcaaaattg aatgaggaat ctatgtcgca cgaaaacaat caccagcagg
    11941 cccagatgtt acgggggact gcttggctaa cggctagtaa ctttatcagt cgcctactcg
    12001 gggctgttta cattatccct tggtacatct ggatgggggc ttatgcagct aaggcaaatg
    12061 gtctctttac catgggttac aatatctatg cttggttctt gttggtttca acagcgggga
    12121 ttccagttgc ggtggccaag caagttgcca agtataatac catgcgagaa gaagagcata
    12181 gctttgccct gattcggagc ttcttaggct ttatgacagg actaggtctg gtttttgctt
    12241 tagtcttgta tgtctttgct ccttggctag cagacttgtc tggcgtgggc aaagacttga
    12301 tcccaatcat gcaaagcttg gcttggggag tcttgatttt cccgtctatg agtgttatcc
    12361 gaggattttt ccaagggatg aataacctca aaccctatgc tatgagccaa attgctgagc
    12421 aggtcattcg tgttatctgg atgctcctag caacctttat cattatgaag ctcggttcag
    12481 gagattatct agcagccgtt acccaatcaa cctttgctgc ctttgtcggt atggtagcca
    12541 gttttgcagt cttgatttat ttccttgccc aagaaggttc actcaaaaga gtctttgaaa
    12601 caggagataa gattaacagt aagcgtctct tggttgatac cattaaggaa gccattcctt
    12661 ttatcctgac agggtctgcc atccagctct tccagatttt ggatcagctg acctttatca
    12721 atagtatgag ctggtttacc aactacagca atgaggactt ggttgtcatg ttttcttatt
    12781 tctcagccaa tcctaataaa atcacgatga ttttgatttc tgtaggggtt tcgattggga
    12841 gtgttggttt gccacttttg acggaaaact atgtcaaggg ggacttgaaa gcagcttctc
    12901 gtctcgttca ggacagtctc accctactct ttatgttctt gctaccagca acggttggag
    12961 tggttatggt aggagaacct ctttatacgg tcttctatgg taagccagat agtttggctc
    13021 tggtcttatt tgtctttgca gttttgcagt ctattatttt aggcttgtac atggtcttgt
    13081 ctccaatgct tcaggccatg ttccgcaacc gcaaggccgt tctctatttt atctatggtt
    13141 ctattgccaa gctagtcttg caactaccta ccatcgccct cttccacagt tatggtcctt
    13201 tgatttcaac aaccattgct ctcatcattc ctaacgtctt gatgtatcgg gatatttgta
    13261 aagtaactgg tgtcaagcgc aaggtgattt tgaagcgaac cattttaatc agtttgctga
    13321 ccctagtcat gtttctgtta ataggaacca tccagtggct gttaggattt ttcttccaac
    13381 caagtggacg tttgtggagc ttcttttatg tagctcttgt cggtgccatg gggggtggac
    13441 tttatatggt tatgagtctg cgtacctatt tattagataa ggtaatagga aaagcccaag
    13501 cagatcgcct gcgagcaaaa tttaagcttt cgtaaggtag catttataaa taaaaggaat
    13561 aagttgaaca atcttttagg agaacttgaa acttattcct tttttagcgt caaaatagct
    13621 aaaattatct ttcaaaaata gaaaatgagg tttttttgat tttttggaaa aaacaattga
    13681 ctaaacaaac ccagagttgt ataataaaac aaatatttaa agcaggaggt tctggaaatg
    13741 aaaaagtcta agagcaaata tctaaccttg gcaggtcttg tcctgggtac aggagtttta
    13801 ttgagcgcgt gtggaaattc tagcactgca tcaaaaacct ataactatgt ttattcaagt
    13861 gatccatcta gtttgaacta tctagcagaa aaccgcgcag caacatccga tattgttgca
    13921 aatttggtag acgggttatt agaaaatgac caatatggga atattattcc atcattagca
    13981 gaggattgga ctgtttctca ggacggtttg acctatacct acaaacttcg taaggatgcc
    14041 aagtggttta cttctgaggg agaagaatat gcgcctgtaa ctgcccagga ttttgtgaca
    14101 ggtttgcaat atgcagctga taaaaaatca gaagctttgt atctagtgca ggactctgtt
    14161 gctggtttgg atgactatat cactggtaaa acaagcgact tttcaactgt cggtgtcaag
    14221 gcacttgatg accaaacggt tcaatatact ttggttaaac cagaacttta ctggaattca
    14281 aaaacacttg caacgatact ttttcctgtt aatgcagatt tcctgaaatc aaaaggggat
    14341 gattttggga aggcggatcc atctagtatt ttgtacaatg gacctttctt gatgaaagca
    14401 cttgtctcaa aatctgctat tgaatataag aaaaacccta attactggga tgctaagaat
    14461 gtctttgtag acgatgtgaa attgacctac tatgatggta gcgaccaaga atcactggaa
    14521 cgtaatttta cagctggtgc ttatactacg gctcgtcttt ttcctaacag ctccagctat
    14581 gaagggatta aagaaaaata caaaaacaat atcatatata gtatgcaaaa ttcaacttca
    14641 tatttcttta attttaacct agataggaag tcttacaatt atacttctaa aacaagtgac
    14701 attgaaaaga aatcgactca ggaagcagtt ctcaataaaa acttccgtca ggctatcaat
    14761 tttgcttttg acagaacatc ttatggggct cagtctgaag ggaaagaagg tgcaacaaag
    14821 attttgcgta acctagtggt tcctccaaac tttgtcagta tcaagggaaa agactttggt
    14881 gaagttgtag tctctaagat ggtcaactat ggtaaggaat ggcaaggtat caactttgcg
    14941 gatggtcaag acccttacta caatcctgag aaagccaagg ctaagtttgc ggaagctaag
    15001 aaagaactcg aagcaaaggg tgttcaattc ccaatccact tggataagac tgtggaagta
    15061 acagataaag taggcataca aggagttagt tctatcaaac aatcaattga atctgtttta
    15121 ggttctgata atgtagtgat tgacattcag caattaacat cagatgagtt tgacagttca
    15181 ggctactttg ctcaaacagc tgctcagaaa gactatgatt tatatcatgg cggttgggga
    15241 cctgattatc aagacccgtc aacctatctc gatattttta atactaatag tggaggagtt
    15301 ctacaaaatc ttggactaga gcctggagaa gccaatgaca aggctaagga agttggactg
    15361 gatgtctata ctcaaatgtt ggaagaagct aataaagagc aagatccagc caaacgttat
    15421 gagaaatatg ctgatattca agcttggttg attgatagtt ctttagttct tccaagtgtt
    15481 tcgcgtgggg gaacaccatc attgagaaga accgtaccat ttgctgctgc ctatggttta
    15541 accggtacaa aagggattga atcatataaa tacctcaaag tacaagataa gattgtcaca
    15601 acagacgaat atgcaaaagc tagagaaaaa tggttgaaag aaaaagaaga atccaataaa
    15661 aaagcccaag aagaattggc aaaacatgtc aaataaaatc taattgtaga taagtttgtg
    15721 taagaagtct ttgtgcttaa aaacgcataa tatcaggtat ataaaatcct agatgttatg
    15781 cgttttgtta taggaagatt tattagattt tatcctcaaa ttgagttatt cccgacttta
    15841 tccgttgaaa tattataagg agtatttatg aaattaaaat tattaagagt agatactaag
    15901 gtgattatgg ggagtttctt acttgttctg tctagtctac ttgctttgtt gcttcccctt
    15961 atcttaaagg gtttaataga tgggagttct attgaaaata taggttccaa agtatttcaa
    16021 tcgtttttga tttttattgg tcaagccttg ttttcttcta ttggttacta tctgtttagt
    16081 caatcgggtg aaaaaaagat agcaaaaatc aggaaaaaag tgatagaggg gttgatttat
    16141 gcagagaaat ccttctttga taagagccaa agtggggagt tgacttctgc cattgtcaat
    16201 gacacgagtg tcattcgtga gtttttaatt acgactttcc caaatattat tctgagttta
    16261 gttatggtac ttggttccat tgtagtctta tttagtcttg attggaatct ttctctactt
    16321 ttattcatca ctcttccttg tatgatgttt attatcttgc tcctttccaa tatcagtgaa
    16381 aagtatagtc gtcgtttaca ggaggaaatc ggatttttaa cagggtaatt gactgaaaag
    16441 attcaagaac atgaattaat taagactaac caagcagaga aaagtgtaca ggatgttttg
    16501 gataattgta ttgaaagggt acaaaacaat tcactgaaat cagatagggt tacttctttt
    16561 gagaccccgt ttgctctctt atttatcttt gcgactatag ctgtgatgct aacctatggg
    16621 ggttatcggg tcagcgcagg atatatatct gtgggaacct tggtttcgtt tttgatttac
    16681 ctctttcaat tacttaatcc tattagtaat atagctaatt ttgtaactgt ttattctagg
    16741 agcaagggat cttcagttgc actggagaac ttgcttgcag ttcctaaaga aaaatttgag
    16801 tgaggaaaat cggtatcagg acaagggttg aattt
//
LOCUS       DAVBNZ010000047        16747 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000047 DAVBNZ010000000
VERSION     DAVBNZ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.047"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            74..538
                     /locus_tag="VQ860_001606"
     CDS             74..538
                     /locus_tag="VQ860_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET3120005.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            696..1121
                     /gene="lacA"
                     /locus_tag="VQ860_001607"
     CDS             696..1121
                     /gene="lacA"
                     /locus_tag="VQ860_001607"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET3120006.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            1152..1667
                     /gene="lacB"
                     /locus_tag="VQ860_001608"
     CDS             1152..1667
                     /gene="lacB"
                     /locus_tag="VQ860_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET3120007.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1678..2607
                     /locus_tag="VQ860_001609"
     CDS             1678..2607
                     /locus_tag="VQ860_001609"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET3120008.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYCASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFTKHGDTFYKVDIPRIQAVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2609..3589
                     /gene="lacD"
                     /locus_tag="VQ860_001610"
     CDS             2609..3589
                     /gene="lacD"
                     /locus_tag="VQ860_001610"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET3120009.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3823..4659
                     /locus_tag="VQ860_001611"
     CDS             3823..4659
                     /locus_tag="VQ860_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3120010.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4695..5012
                     /locus_tag="VQ860_001612"
     CDS             4695..5012
                     /locus_tag="VQ860_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3120011.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5012..6703
                     /locus_tag="VQ860_001613"
     CDS             5012..6703
                     /locus_tag="VQ860_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3120012.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            6918..8324
                     /gene="lacG"
                     /locus_tag="VQ860_001614"
     CDS             6918..8324
                     /gene="lacG"
                     /locus_tag="VQ860_001614"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3120013.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNVKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTTLEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIIRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8414..8626
                     /locus_tag="VQ860_001615"
     CDS             8414..8626
                     /locus_tag="VQ860_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET3120014.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(8905..9666)
                     /locus_tag="VQ860_001616"
     CDS             complement(8905..9666)
                     /locus_tag="VQ860_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3120015.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9848..10810)
                     /gene="nrdF"
                     /locus_tag="VQ860_001617"
     CDS             complement(9848..10810)
                     /gene="nrdF"
                     /locus_tag="VQ860_001617"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET3120016.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(10998..13157)
                     /gene="nrdE"
                     /locus_tag="VQ860_001618"
     CDS             complement(10998..13157)
                     /gene="nrdE"
                     /locus_tag="VQ860_001618"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET3120017.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13238..13456)
                     /gene="nrdH"
                     /locus_tag="VQ860_001619"
     CDS             complement(13238..13456)
                     /gene="nrdH"
                     /locus_tag="VQ860_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET3120018.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13807..14070
                     /locus_tag="VQ860_001620"
     CDS             13807..14070
                     /locus_tag="VQ860_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET3120019.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14076..15809
                     /gene="ptsP"
                     /locus_tag="VQ860_001621"
     CDS             14076..15809
                     /gene="ptsP"
                     /locus_tag="VQ860_001621"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET3120020.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16064..>16747
                     /gene="phtA"
                     /locus_tag="VQ860_001622"
     CDS             16064..>16747
                     /gene="phtA"
                     /locus_tag="VQ860_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3120021.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT         5214 a         3020 c         3475 g         5038 t
ORIGIN      
        1 tatcaatcat gaactaggat tctagttttg caggaagtct aataaagaaa ctagcaaggt
       61 caggccttac tttattggtg gacatccagg atttaattgt cttctacttg atgatgaagt
      121 ctatgaagat tattatctag agtttgagaa agaagagatt tgctctgttc cacgtccttt
      181 cccagaaaca ggtatgttgg atttccaaga tagaagtcca tggctagagg gacaaaaaga
      241 aatagatctt agttatgatc ttttcagcac agatgcagtg actttggatg aattgcaatc
      301 tcgaacaatt gcccttcgtt ctcttaaaca tgataaggga ttgaaagtgc attttgcaga
      361 atttccaaac ctcatcatct ggtcaacttt gaacaaggga cctttcatta cctttgaacc
      421 atggtctggc ttgtcaacat tccttgaaga aggagatcat ttagaagata agaagaatgt
      481 ttgtctctta gaagccaatc aggttgaaga attagggttt gagatagaag ttttataaaa
      541 aaagtaaaaa ataaataaca aaaacaaaca caaactgttg acttcttcaa acaatagtag
      601 tatattatgt ttgtgaggac taattgactg ttttttaaag acagccaata cactgctgga
      661 atccagcata gaaaaaataa aaaggagtat acaatatgtc tattgttatc ggtgcagatg
      721 ctgcaggttt gagattgaaa gaagttgtga aagacttctt agaaaaagaa aacttccacc
      781 ttgtggatgt tacagctgaa ggtcaagact ttgttgatgt gactctcgct gttgctgcag
      841 aagtaaacaa agaagaacaa aaccttggta tcgtgattga tgcttatgga gctggtccat
      901 ttatggttgc aactaagatc aaaggaatgg ttgctgcaga agtatctgac gaacgttcag
      961 cttatatgac tcgtggccac aacaactcac gtatgatcac tatgggggca caacttgttg
     1021 gtgatgaatt ggctaaaaac atcgctaaag gatttgttaa tggtaaatac gacggtggtc
     1081 gtcaccaaat ccgggttgac atgttgaaca aaatgtgcta attagattat agtaagaaag
     1141 gtaagttaaa aatgagaatt gcaattggat gtgaccacat cgtaacagat gaaaaaatgg
     1201 cggtttcaga atttttgaaa tcaaaaggat atgaagtcat tgactttggt acctatgacc
     1261 atacacgtac tcactaccca atctttggta aaaaagtagg ggaagcagta actagtggtc
     1321 aagctgatct cggggtatgt atctgtggta ctggtgttgg tatcaacaac gctgtaaata
     1381 aagttccagg tgttcgttct gccttggttc gtgatatgac aacagccctt tatgctaaag
     1441 aacaattgaa cgccaacgtt atcggttttg gtggtaagat tactggtgaa ttgcttatgt
     1501 gtgatatcat cgaagctttc attcatgctg aatacaaacc atctgaagaa aacaaaaaat
     1561 tgattgcgaa aattgaacac cttgaaagtc acaatgctca acaaacagac gcaaacttct
     1621 tcactgaatt ccttgaaaaa tgggatcgtg gagaatacca cgactaagag gtaacctatg
     1681 attttaacag ttacaatgaa cccatccatt gatatttcct atcccttgga tgagttgaag
     1741 attgatactg tcaatcgtgt ggtggatgta accaaaacgg ctggtggtaa gggactcaat
     1801 gttacccgag tactttcaga atttggcgat tctgttcttg ctactggttt agtgggtggc
     1861 aaacttggtg agtttttggt tgaacatatc gataatcaag taaagaaaga tttcttctca
     1921 attcagggag aaactcgtaa ctgtatcgct attctccacg gagacaacca aacagaagtt
     1981 cttgaaaaag gtcctgaagt attggaacag gaaggtcaag actttttgga acatttcaaa
     2041 aaactcttgg agtcagttga agtagtggcc atctcaggta gtctgccagc tggccttcca
     2101 gttgattact gtgcgagctt ggtagaactt gctaatcaag ctggcaagcc tgtagtcttg
     2161 gactgctcag gtgcagcact tcaggctgtt cttgaatcac cccataaacc aacagtcatc
     2221 aaaccaaata atgaagaatt gtctcagctt cttggaagag aagtttctga ggatttggat
     2281 gaattaaaag aagtacttca agaacctttg tttgcaggga ttgaatggat tatcgtttca
     2341 cttggtgcca acggtacttt taccaaacat ggtgacactt tctacaaggt agatattcct
     2401 agaattcagg cggtaaatcc tgttggatct ggagactcta ctgtggcagg aatttcttca
     2461 ggacttcttc acaaagaatc ggatgcagaa ttactcatca aggcaaatgt ccttggtatg
     2521 ctcaatgctc aagaaaaaat gactggtcat gtcaacatgg ccaactatca agctctatat
     2581 gatcaattaa tagtaaaaga ggtataaaat ggctttaaca gaacaaaaac gtgtacgctt
     2641 agaaaaactt tctgatgaaa atggtatcat ctcagctctt gcatttgacc aacgtggtgc
     2701 tttgaaacgc ctcatggctc aacaccaaac agaagaacca actgtggccc aaatggaaga
     2761 acttaaagtt ttggtagcag atgaattgac taaatacgct tcatctatgc ttcttgaccc
     2821 tgagtatgga cttccagcaa ctaaagctct tgatgaaaaa gctggtcttc tccttgctta
     2881 tgaaaaaaca ggttatgaca caacaagcac aaaacgcttg ccagactgct tggatgtttg
     2941 gtctgcaaaa cgtattaaag aagaaggtgc agatgcagtt aaattcttgc tttactatga
     3001 tgtagatagc tcagacgaac tcaatcaaga aaaacaagcc tacatcgaac gcatcggttc
     3061 tgagtgtgtg gctgaagata tcccattctt ccttgaaatc cttgcttacg atgaaaaaat
     3121 tgcagacgca ggttctgtag aatacgctaa agtaaaacca cacaaagtta tcggtgctat
     3181 gaaagtcttt tcagacccac gctttaacat tgatgtcttg aaagttgaag ttcctgttaa
     3241 cattaaatat gttgaaggct tcgctgaggg tgaagtggtt tacacacgtg aagaagcagc
     3301 agccttcttc aaagcgcaag atgaagcaac gaacttgcca tacatctact tgagtgctgg
     3361 tgtatcagct aaactcttcc aagatactct tgtatttgct catgaatcag gtgcaaactt
     3421 taacggagtt ctttgtggcc gtgctacatg ggcagggtca gttgaagctt acatcaaaga
     3481 tggtgaagca gcagctcgcg aatggcttcg cacaactgga tttgaaaaca ttgatgagct
     3541 caataaagtt cttcaaacaa cagcgacttc atggaaagaa cgtgtgtaag aaagtcctcc
     3601 tagtttagga acatgaatct aaaaaaattt aaaaaaagtt gtatgtaaag gtttacaaaa
     3661 taacttactt gtgctatact taaatcacaa gttaatacaa ggtgagtgtt actaagtaat
     3721 attaggcatg atcacaggtg aattagaaat cagctgattt tctagttcat ttgtggtcat
     3781 tttttgtact catatacctt taaaatataa aaggaggttg acatgtatcg aattctaaat
     3841 ccaatgaatc acaatgtctc gcttgtcaga aatgataagg gagaagaggt gattgtaatt
     3901 ggtaagggga ttgcattcgg aaagaagaag ggggatttga ttgctgaaaa tcaggttgag
     3961 aaaatctttc ggatgaagac cgaagagtcc agagaaaact ttatggctct tctcaaagat
     4021 gttccgcttg attttatcac agtgacctat gaaattattg ataagctatc aaagaaatat
     4081 cattatccga ttcaagagta tctctatgta accttgacag atcatattta ctgttcttat
     4141 caagctctaa ctcaaggaag gtacaaggat agtaatctgc cagatatttc cgctaagtat
     4201 cctgtcgctt ttcaaatcgc aaatgaagct tttgaaattt accgtcagaa gctagcagat
     4261 cattttcctg aggacgaaat tattcggatt gcttatcatt tcattaatgc tgaaggtgaa
     4321 aatgaagtgg aacttgtgga gtcgattgat aagaggaaag aaattctcag gaatgttgaa
     4381 gaagttttaa cggactatgc aattcaacga actaaaaaga ataaccattt ctatgatcgc
     4441 tttatgatcc atttgaatta tttcttggat tatttagaca gatctagaga tgataaccaa
     4501 tcacttctgg atatggaaga tcatattaaa caatcctatc caaaagcctt cgagattggt
     4561 tccaagatct atgatgtgat tacgcaacat acgggtcttg atttgtataa aagtgaacga
     4621 gtttatctag ttctacatat ccaacgttta ttgtcataaa aatttattta aaactatata
     4681 aggagaattc tatcatgaat agagaagaag taacattgtt aggttttgaa atcgtagcct
     4741 atgctggcga tgctcgttca aaactattgg aagccttgaa ggctgctgaa gctggtgatt
     4801 ttgaaaaagc ggacgctctg gtagaggaag ctggtagctg tattgcagag gctcaccacg
     4861 cgcaaacaag tctattgact aaggaagctt ctggtgagga cttagcgtat agtgtgacca
     4921 tgatgcatgg tcaagatcac ttgatgacaa ctatcttgtt aaaagaccta atgcaccatt
     4981 taattgaact ttacaagaga ggagttaaat aatgaataaa ctaattgcat ttatcgagaa
     5041 aggaaagcct ttctttgaaa aactatctcg taatatctat cttcgtgcta ttcgtgatgg
     5101 tttcattgca ggtatgcctg ttattctctt ctcaagtatc tttatcttga ttgcctttgt
     5161 accaaactca tggggcttta aatggtctga tgaagttgta gcctttctga tgaaacctta
     5221 tagctattct atgggtattc tggctctctt ggtagctggt acaacagcta agtcattgac
     5281 tgactcagta aaccggagca tggaaaaaac caatcaaatc aactatatgt caacattgtt
     5341 ggcagcaatt gttggtttgt tgatgttggc agctgatcct atcgaaagtg gtctagctac
     5401 tggattcttg ggaacaaaag gtttgctttc agccttcctt gctgccttcg ttactgtagc
     5461 catctataag gtctgtgtta agaacaacgt cactattcgt atgcctgacg aagttccacc
     5521 aaatatctca caagtcttta aagatgtgat tccattcact ctatcagtgg tttctcttta
     5581 tgctcttgat ttactagctc gtcattttgt tggttctagt gtggcagaat caatcggtaa
     5641 attcttcgca ccactcttct cagcagcaga cggatacctt ggtattacca ttatctttgg
     5701 tgcctttgcc ttcttctggt ttgttgggat tcatggtcca tctatcgttg aacctgctat
     5761 cgcagcgatt acctatgcaa atgctgaagt caacttgaac cttctccaac aagggatgca
     5821 tgcagacaag attcttactt ctggtacaca aatgtttatc gttaccatgg gtggtacagg
     5881 tgcgacattg gtcgttccat ttatgttcat gtggttgaca aaatcgaaac gtaaccgtgc
     5941 aatcggacgt gcttcagtag ttcctacctt cttcggtgta aatgaaccaa tcttgtttgg
     6001 tgcacctctt gttttgaatc caatcttctt cattccattt atctttgctc caattgcaaa
     6061 cgtatggatt ttcaaattct ttattgaaac tcttggaatg aactcattca ctgctaatct
     6121 accatggaca actccagctc cactaggtct agttcttgga actaacttcc aagtgctatc
     6181 attcattctt gctgcccttc taattgtggt tgacgtagtt atttattacc cattccttaa
     6241 agtctatgat gaacaaattc ttgaagaaga acgttcaggt aagtctaatg atgaattgaa
     6301 agaaaaagtt gctgcaaact tcaacactgc aaaagcggat gctattcttg aaaaagcggg
     6361 tgtcgatgca gcacaaaata ccatcactga agaaacaaat gtcctcgttc tctgtgctgg
     6421 tggaggtaca agtggactcc ttgcaaatgc tttgaataag gcagcagcag aatacaatgt
     6481 ccctgtgaaa gcagcagcag gcggctatgg tgctcaccgt gaaatgttgc cagagtttga
     6541 tttggttatc cttgctcctc aagttgcttc aaactttgaa gatatgaagg cagaaacaga
     6601 taagctcggt attaaacttg ctaagacaga aggcgctcaa tacatcaaat taactcgtga
     6661 tggaaaaggt gccctagcat tcgtacaaga gcaattcgat taaggctagg aactgtgaaa
     6721 cagtctccca tcgttacgga aatcgctatg gcgaatttcc taatcgcctt attaattcgt
     6781 cggtaaaaag atatcgtttt tacctcctca tgtcacaatt cagtgacttg gtacaagaag
     6841 tgagatggag aagcatggct cactgactcc tctcctctca cttttacttt atttaaatca
     6901 agaaataggt gaaaaaaatg acaaaaacac ttccaaaaga ctttattttc ggtggcgcaa
     6961 cagctgctta tcaagcagaa ggtgctacac atactgatgg aaaaggacca gttgcttggg
     7021 ataaatatct tgaggataac tactggtaca ctgccgaacc agctagtgat ttttacaatc
     7081 gatatccagt tgacctcaag ctagcagaag agtatggtgt caatggtatt cgaatttcta
     7141 ttgcctggtc acgtattttc ccgactggtt acggccaagt aaatgttaaa ggtgttgagt
     7201 tttatcataa tttatttgca gagtgtcaca aacgtcatgt tgagcccttt gtaactcttc
     7261 atcactttga cacgccagaa gctctccatt caaatggaga cttcttaaac cgtgaaaata
     7321 tcgaacattt tgtagactac gctgccttct gttttgaaga atttccagaa gtaaactatt
     7381 ggacaacctt taatgaaatt ggaccaatcg gtgatggtca atatttggtt gggaaattcc
     7441 ctccaggtat ccagtacgac cttgccaaag tctttcaatc acaccacaat atgatggtgt
     7501 ctcatgcgcg tgcagtcaag ctatataaag ataaaggcta taaaggggaa attggtgttg
     7561 ttcacgctct gccaaccaag tatcctttgg atcctaaaaa tccagcagat gttcgtgcag
     7621 ctgagttgga agatatcatc cacaataaat tcatcttaga cgcaacttat ctaggtcgct
     7681 attcagctga aaccatggaa ggtgtcaacc atatcttatc agtcaatggt ggtagtttgg
     7741 atcttcgtga agaagatttt acaacattag aagctgcaaa agacttgaat gatttcctag
     7801 gaatcaacta ctatatgagt gactggatgg aagcctttga tggagaaact gaaattatcc
     7861 ataatggtaa aggtgaaaaa ggaagctcta agtatcaaat caaaggtgtt ggtcgtcgtg
     7921 tagctcctga ctatgtacca cgcacggatt gggattggat tatctaccct caaggtttgt
     7981 atgaccaaat catacgtgtg aagaaagatt atcctaacta caagaagatt tacatcactg
     8041 aaaatggtct cggctataaa gatgagttcg ttgataacac tgtttacgat gatggtcgta
     8101 ttgattacgt gaaacaacac ttggagatct tgtctgatgc gattgcagat ggagctaatg
     8161 taaaaggtta cttcatttgg tcattaatgg atgtcttctc atggtcaaac ggttatgaaa
     8221 aacgttacgg tctcttctac gtagattttg aaactcaaga acgttatcct aagaaatcag
     8281 ctcactggta taagaaagta gcggaaactc agattataga ctagtagaat tagtcattag
     8341 atatagaatt ttagtgagtc aaaaagatgt tcaaagattt tatccaatct atttatgaaa
     8401 aaaagtttat attataaatt tcgaaaaatg ctctcaaata ccgtgtttga cgagtgaaga
     8461 attgaaaagt cttggaaaat ggtatgtctc gactggtaaa gaatggattt gtcattcaga
     8521 tgatgagctg gaagaattta aaaatctatt tttaaatttt atcaatcctg aagaatggga
     8581 tactatctcc tttgattcag attttatgcc gtttcaacaa tcgtaaccaa tttctcaaaa
     8641 aagttaaatc ttatatttag tactctgtaa aactcttatc taatcacgtt gcttatactc
     8701 aatgaaaatc aaagagcaac tttaaactag gaagcgagtc gcagatttct caatgcatag
     8761 ctttgaggaa ttgggcaaaa agtctttgat atagaaaaac gcatagtatc aggtgtttca
     8821 acacctgata ttatgcgttt tattgtggga agatttactt tttttcttct gaaattgagt
     8881 tgttacccag gctctttcag tttattaagg cttgatgact ttaatgtgtt tagatagctt
     8941 aaaaaggatt gaatcactta gtttagaatc tgaaacaata gtatcaagat ttgatacatt
     9001 ataaaaagta taaaaatcaa acttattgaa cttgctatga tctgcgagta aatatttttt
     9061 attagaatta tttaaagcga tgcgttgagc ctctccctct tcctcgctaa aagtagctag
     9121 agctccgttt tgaataccat tacagctaac gaaagcttta gaaaattgga gattagagag
     9181 attttgtagg gtcaatgtac caacaaaagc acctgtaata tcgcgataat ttccacctat
     9241 taaaatcaaa tctgttaatt ttcgttcgct taaaatcaga aaaacaggta gactgttggt
     9301 tacgacgcgg atattgtcaa taggcaactc acgcgcaaaa aactctaatg ttgttcctgg
     9361 tccaatgaaa atagtttctc tttcttctac tagactgcct gcaaaatggg ctatttcttg
     9421 tttttctgcc gtttggaggg cttgtttttc aatatttgat cgctcattag tcaaaaggga
     9481 gttggttcga agtttttcag ctccaccatg cacacgaatc agcaaatctt tatcagctaa
     9541 ttcctgtaaa tagcgccttg cagtcatatc tgaaacggct atttcgtcca taatctgttt
     9601 aactgttatg gttcctttac tatttactat ctctaaaatt ttggttaatt tttcttgttt
     9661 gagcatatta tcacctcgtt tcctactact atcttaccat aaacaaactc atcattcaaa
     9721 tacaaaaaca acaaaatgaa acaaaaacaa aaatatcgaa gtttgttttc aaaactttcg
     9781 atatttttgt tgggttataa ctttgatgtt tctagtttac tttttgatga ttgagagtga
     9841 tggagaatta gtctaaaccg tagttatagt catcgtcttg catggcttca acttcgccaa
     9901 gaaggtaacc atttccgact tgagagaaga agtcatggtt ggaagttcct gttgaaatac
     9961 cgttcataac gattgggttg acatcttcag ctgaatctgg gaaaagtgga tcttgtccca
    10021 tgttcatgag agctttattg gcattgtagc gaaggaaggt tttaacctct tcagtccaac
    10081 caacaccgtc ataaagactc tctgtgtagc cttcttcatt ttcataaaga gtatagagta
    10141 ggtcgtacat ccattctttg agtttttctt gctcttcttc aggcaattca ttgaaaccaa
    10201 gttggaattt gtaaccaatg taggttccgt gaacagactc gtcacgaata atcaatttaa
    10261 tgatttctgc aacgttggct agtttgttgt taccgagata gtagagggga gtgaagaaac
    10321 cagagtagaa gaggaaggtt tcgaggaaga cgctggcaac tttcttttca agtgggctgc
    10381 cgtttaggta gatttcgttg acaatctcag ccttcttttg taggtaagga ttggtattgg
    10441 tccattcgaa aatttcttca atctcagcct tagtattcaa ggtagaaaag attgatgagt
    10501 aagatttagc gtggacagat tccataaatt ggatgttatt gaaaacagct tcctcatgtg
    10561 gtgtacggat gtctgcgcga agggcttgaa ccccagtttc agattgcata gtgtcaagaa
    10621 gggttaaacc accaaaaact tttccgacca agtctttctc tttgttagat agctttctcc
    10681 agtcatccaa gtcgtttgat aagggaatac gtgtatcgag ccaaaattgc tccgtcagtt
    10741 tttcccaagt tgatttgtcg atgacatctt cgatggcatt ccagttaatg gctttgtagt
    10801 aagtttccat ttaaaatctc tttctgtgtt tagtattgcg aactcacaat tatttctact
    10861 ttaccataat tctataggag tatcgcacaa aaagtcggaa gcccgacttt taaaatgtta
    10921 cataaattat gttatgacat agtagatttg attttatcag tgctgcttag ggaaaaataa
    10981 tgtttctatg ctagaaacta aatcacacag ctttcacatt ggttggcgcc gacttctcca
    11041 ccgtcatctg taaaggtacg gacgtagtag atagacttga ttcccttgtt aaaggcatag
    11101 ttacgaagga tggacaaatc acgtgtcgtt tgtttatttt ccctcttcca ttcgtaaagg
    11161 ccttttggaa tgtcactgcg catgaagagg gtgagtgaaa gtccttgatc cacgtgttca
    11221 gtcgcagcag cgtaaacatc gatgacttta cgcatatcca tatcgtaggc agaagtgtag
    11281 taaggaatgg tttctgtaga caagccagca gcagggtagt agattttacc aattttcttc
    11341 tcttggcgtt cttcgatacg ttgcgtaatc gggtggatag aagcagaaac gtcgttgata
    11401 tagctgatag aaccatttgg cgctacagca aggcgatttt ggtggtaaag accatcttct
    11461 tgaaccttgt cgcgaagttc agcccaatca gcaacaccag ggataaaaac atttttgaag
    11521 agttctttaa cacggtctga tgttggaaca aattcaccag ttacatactt gtcaaagtaa
    11581 cttccgttag catagtctga tttttcaaag ttgtggaagg taataccacg ttcacgcgca
    11641 atattgtttg actctaccaa ggtccagtag ttcataagca taaagtagat gcttgtaaat
    11701 tcaacagact caggtgaacc atattcaatg agttgttggg caaggtagct gtgcagtccc
    11761 atggcaccga gaccaaaggt gtgggcttgg ctatttccat ggtcaatcgt tggtacagct
    11821 acgatatgtg aactatctgt aacgaaagta agggcacgaa ccatagcacg gatagaacga
    11881 ccaaaatcag gtgaagtcat catgttaacc acgttggttg aacccagatt acatgaaaca
    11941 tctgttccca tttgaaggaa ttcttgagca tcgttgatca agcttggttc ttgaacttga
    12001 agaatctcag aacacaagtt actcatgata atctttccat caacaggatt tgcacggtta
    12061 gccgtatcga tgttgactac ataaggatag ccagactctt gttgcaattt agagatttca
    12121 gtttccaaat cccgcgcctt gatttttgtc ttgcgaatat ttggatttgc gaccaattca
    12181 tcgtattttt cagtaatgtc gatgtaattg aatggcacac cgtattcttt ttctacagag
    12241 taagggctga agaggtacat ttcttcattt ttacgagcca attcgtagaa tttatcaggt
    12301 actacaacac caagtgatag agtcttgaca cgtacttttt catcagcgtt ttctttctta
    12361 gttgaaagga aagcgatgat atctgggtga aagacgttga ggtagacaac accagcacct
    12421 tgacgttgcc ccaattggtt ggagtaagag aagctgtctt caaaaagctt cataacagga
    12481 acgacacctg aagcagctcc ttcatagcct ttgataggtg caccagcttc acgaaggttg
    12541 ctgagggtaa ttcccacacc accaccaata cgtgaaagtt gaagagctga gttgatagaa
    12601 cgtccgatag agttcatatc atccgtcact tggattagga aacaagatac caactcccca
    12661 cgacgagcac gtccagcatt caagaaggaa ggagtagcag gttggtagcg ttggtggatg
    12721 atttcattgg caatatcgat tgcaacagct tcattcccat cagcgaaata aagggcgttg
    12781 aagaagacac ggtcttccat attttcaaga tagtattcac cgtcattagt ctttaaggca
    12841 tattgattgt aaaatttata agctgccatg aatgacttga attggaagtt ttggtctttg
    12901 ataaattgag ccaattcttc caagaactct ggacggtatt tcttgataaa ggctgtttcg
    12961 atgtagttgt gttcaatgag gtaattgatt ttgtctttga ttgaatcaaa aaccatagtg
    13021 tttggaacta cattttcttt aaagaaagca tccaaggctt ccttatcttt atgaagcatg
    13081 atttgtccat taacaggacg gttaatttcg ttattaagac ggaagtaagt cacgtcttca
    13141 agatgtttta atcccataaa atttccctta tctaattaca aaagaaaggc ttctaagtta
    13201 gccctaaaag cagtttcttc tggatgatgt actaagatta tgctaattgt ttcagttttc
    13261 ctggttggaa acctgaaaag acttcagttg gtgtttggat aacaggagct gcgctaaaac
    13321 cgagctcttt aacttgatcg acgtactcag gttgctcatc aagattgatt tcacgataag
    13381 agacattatt actgtccaag aaacgcttgg tcattttaca ttggacacaa ttgtttttag
    13441 aataaacggt taccattgtg taactcctct tcaaaattta atactatctt agtatatcag
    13501 aaaataaaat tttgtcaatg atttgaacta aatatagtgg tgttcttttg ttgtttttat
    13561 atataaacac aatatatagt gtttgtattg tgaaatagca atgattatcc tataaattgt
    13621 ttttaaagaa actatatcct gtgttttgtt atctaggata gaagattttc agcaagttat
    13681 ctgaaaggaa attgaaggaa aatccagaaa atgcttgaaa aaaatcctag aagatggtat
    13741 aatactaaat tgtaagggtt atcacatata actcaaaaaa agaaagaaca aaaggagagt
    13801 caaactatgg cttctaaaga tttccacgta gtggcagaaa caggtattca cgcacgtcca
    13861 gcaacattgt tggtacaaac tgctagcaaa tttgcttcag atatcactct tgagtacaaa
    13921 ggtaaatcag ttaaccttaa atcaattatg ggtgttatga gtcttggtgt tggtcaaggt
    13981 gctgacgtaa ctatctcagc tgaaggtgca gatgcagatg acgctatcgc tgcaatctca
    14041 gaaacaatgg aaaaagaagg attggcataa gggaaatgac agaaatgctt aaaggaatcg
    14101 cagcatctga cggtgttgca gttgcaaaag catatctact cgttcagccg gatttgtcat
    14161 ttgagactat tacagtcgaa gatacaaacg cagaagaagc tcgccttgat gccgctctac
    14221 aggcatcaca agacgagctt tctgttattc gcgagaaagc agtaggtacg ctcggtgaag
    14281 aagcagctca agtttttgat gctcacttaa tggttcttgc tgacccagaa atgatcagcc
    14341 aaatcaagga aactatccgt gcgaagaaag tgaatgcaga agcaggtctg aaagaagtta
    14401 cagatatgtt tatcactatc tttgaaggca tggaagacaa cccatacatg caagaacgcg
    14461 cagcggatat ccgcgacgtg acaaaacgtg tattggcaaa ccttcttggt aaaaaattgc
    14521 caaacccagc ttctatcaat gaagaagtga ttgtgattgc gcatgacttg actccttcag
    14581 atacagctca attggacaaa aactttgtaa aagcttttgt aaccaacatt ggtggacgta
    14641 caagccactc agctatcatg gcacgtacac ttgaaattgc tgctgtatta ggtacaaaca
    14701 acatcactga aatcgttaaa gacggtgaca tccttgctgt taacgggatc actggagaag
    14761 tgattatcaa cccaacagat gaacaagcgg cagaatttaa agcagctggt gaagcctatg
    14821 cgaaacaaaa agctgaatgg gcacttttga aagatgctca aacagtgact gctgacggta
    14881 aacacttcga gttggctgcc aatattggta ctccaaaaga cgttgaaggt gttaacaaca
    14941 acggtgcaga agctgttgga ctttaccgta cagagttctt gtacatggat tctcaagact
    15001 tcccaactga agatgagcag tatgaagcat acaaggctgt tcttgaagga atgaacggta
    15061 aacctgttgt cgttcgtaca atggatatcg gtggagataa ggaacttcct tacttcgata
    15121 tgcctcacga aatgaaccca ttccttggat tccgtgctct tcgtatctct atctctgaga
    15181 ctggagatgc tatgttccgc acacaaatcc gtgctcttct tcgtgcgtct gttcacggtc
    15241 aattgcgtat catgttccca atggttgcgc tcttgaaaga attccgtgca gcgaaagcag
    15301 tctttgatga agaaaaagca aaccttcttg ctgaaggtgt tgcagttgcg gataacattc
    15361 aagttggtat catgatcgag attcctgcag cggctatgct tgcagaccaa tttgctaaag
    15421 aagttgactt cttctcaatt ggtacaaatg acttgatcca atatacaatg gcagcagacc
    15481 gtatgaacga acaagtttca tacctttacc aaccatacaa cccatcaatc ctacgcttga
    15541 ttaacaatgt gatcaaagca gctcacgctg aaggtaaatg ggctggtatg tgtggtgaga
    15601 tggctggtga ccaacaagct gttccacttc ttgtcggaat gggcttggat gagttctcta
    15661 tgtcagcaac atctgtactt cgtacacgca gcttgatgaa gaaactcgac acagctaaga
    15721 tggaagagta cgcaaaccgt gcccttacag aatgctcaac aatggaagaa gttcttgaac
    15781 ttcaaaaaga atacgttaat tttgattaat cgaaaagtcc ctgcaactca gttacaggga
    15841 ctttttttga tattttaaaa agaattttca agaaaatctt tcttataaaa agtccaacct
    15901 tgaaaaagta gtggtcagaa caaaaaatac ttaaatggtt cataaaattc ttgacaagtt
    15961 ggagatttag gagtaaacta ttaaccagtt aagtaataga gaggagtttc tgcaatttag
    16021 aaatgaattg caactagaaa tatcaaatag aaagagagtt tcgatgaaaa ttaataagaa
    16081 ataccttgtt ggttctgcgg cagctttgat tttaagtgtt tgttcttacg agttgggact
    16141 gtatcaagct agaacggtta aggaaaataa tcgtgtttcc tatatagatg gaaaacaagc
    16201 gacgcaaaaa acggagaatt tgactcctga tgaggttagc aagcgtgaag gaatcaatgc
    16261 tgagcaaatc gtcatcaaga taacagacca aggctatgtc acttcacatg gcgaccacta
    16321 tcattattac aatggtaagg ttccttatga tgcgattttc agtgaagaat tactcatgaa
    16381 agatccaaac tataagctaa aagatgagga tattgttaat gaggtcaagg gtggatatgt
    16441 tatcaaggta gatggaaaat actatgttta ccttaaggat gctgcccacg cggataacgt
    16501 ccgtacaaaa gaggaaatca atcgacaaaa acaagaacat agtcaacatc gtgaaggtgg
    16561 gactccaaga aacgatggtg ctgttgcctt ggcacgttcg caaggacgct atactacaga
    16621 tgatggttat atctttaatg cttctgatat catagaggat actggtgatg cttatatcgt
    16681 tcctcatgga gatcattacc attacattcc taagaatgag ttatcagcta gcgagttggc
    16741 tgctgca
//
LOCUS       DAVBNZ010000048        16455 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000048 DAVBNZ010000000
VERSION     DAVBNZ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.048"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..906
                     /gene="lytB"
                     /locus_tag="VQ860_001623"
     CDS             <1..906
                     /gene="lytB"
                     /locus_tag="VQ860_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3120022.1"
                     /translation="YMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDS
                     DGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYES
                     DGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNY
                     SAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKD
                     KNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEY
                     ASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ860_001624"
     CDS             complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ860_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET3120023.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ860_001625"
     CDS             2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ860_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET3120024.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3205..3600
                     /locus_tag="VQ860_001626"
     CDS             3205..3600
                     /locus_tag="VQ860_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET3120025.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3617..4516
                     /gene="era"
                     /locus_tag="VQ860_001627"
     CDS             3617..4516
                     /gene="era"
                     /locus_tag="VQ860_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET3120026.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4565..5389
                     /gene="mutM"
                     /locus_tag="VQ860_001628"
     CDS             4565..5389
                     /gene="mutM"
                     /locus_tag="VQ860_001628"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET3120027.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYHKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5389..5994
                     /locus_tag="VQ860_001629"
     CDS             5389..5994
                     /locus_tag="VQ860_001629"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET3120028.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5981..7180
                     /locus_tag="VQ860_001630"
     CDS             5981..7180
                     /locus_tag="VQ860_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HET3120029.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ860_001631"
     CDS             7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ860_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3120030.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7369..7602
                     /gene="secG"
                     /locus_tag="VQ860_001632"
     CDS             7369..7602
                     /gene="secG"
                     /locus_tag="VQ860_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET3120031.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7704..10058
                     /gene="rnr"
                     /locus_tag="VQ860_001633"
     CDS             7704..10058
                     /gene="rnr"
                     /locus_tag="VQ860_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET3120032.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLKLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     AGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNYGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10021..10488
                     /gene="smpB"
                     /locus_tag="VQ860_001634"
     CDS             10021..10488
                     /gene="smpB"
                     /locus_tag="VQ860_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET3120033.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10504..11364
                     /gene="tehB"
                     /locus_tag="VQ860_001635"
     CDS             10504..11364
                     /gene="tehB"
                     /locus_tag="VQ860_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET3120034.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11437..12390
                     /gene="coiA"
                     /locus_tag="VQ860_001636"
     CDS             11437..12390
                     /gene="coiA"
                     /locus_tag="VQ860_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET3120035.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12409..14211
                     /gene="pepF"
                     /locus_tag="VQ860_001637"
     CDS             12409..14211
                     /gene="pepF"
                     /locus_tag="VQ860_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3120036.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14213..14926
                     /locus_tag="VQ860_001638"
     CDS             14213..14926
                     /locus_tag="VQ860_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET3120037.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14993..15934
                     /gene="prsA"
                     /locus_tag="VQ860_001639"
     CDS             14993..15934
                     /gene="prsA"
                     /locus_tag="VQ860_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET3120038.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDIITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16051..16392)
                     /locus_tag="VQ860_001640"
                     /pseudo
     CDS             complement(16051..16392)
                     /locus_tag="VQ860_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4950 a         3074 c         3687 g         4744 t
ORIGIN      
        1 tacatggcga aaaatgagac agtagatggt tatcagcttg gaagcgatgg taaatggctt
       61 ggaggaaaag ctacaaatga aaatgctgct tactatcaag tagtgcctgt tacagccaat
      121 gtttatgatt cagatggtga aaagctttcc tatatatcgc aaggtagtgt cgtatggcta
      181 gataaggata gaaaaagtga tgacaagcgc ttggctatta ctatttctgg tttgtcaggc
      241 tatatgaaaa cagaagattt acaagcgcta gatgctagta aggactttat cccttattat
      301 gagagtgatg gccaccgttt ttatcactat gtggctcaga atgctagtat cccagtagct
      361 tctcatcttt ctgatatgga agtaggcaag aaatattatt cggcagatgg cctgcatttt
      421 gatggtttta agcttgagaa tcccttcctt ttcaaagatt taacagaggc tacaaactac
      481 agtgctgaag aattggataa ggtatttagt ttgctaaaca ttaacaatag ccttttggag
      541 aacaagggcg ctacttttaa ggaagccgaa gaacattacc atatcaatgc tctttatctc
      601 cttgcccata gtgccctaga aagtaactgg ggaagaagta aaattgccaa agataagaat
      661 aatttctttg gcattacagc ctatgatacg accccttacc tttctgctaa gacatttgat
      721 gatgtggata agggaatttt aggtgcaacc aagtggatta aggaaaatta tatcgatagg
      781 ggaagaactt tccttggaaa caaggcttct ggtatgaatg tggaatatgc ttcagaccct
      841 tattggggcg aaaaaattgc tagtgtgatg atgaaaatca atgagaagct aggtggcaaa
      901 gattagtact ataagtgaat atgatttgag tgaatagtaa gttaaaaatc ctgatttcaa
      961 gtaaaatcag gattttttca tggatgcaat ttttttggag tctggtgtga cgcggagggt
     1021 cttttgtcct gtgtaagtga caaagccggg ttttccacca gttggtttat tgagtttttt
     1081 gacttcaatc atatctacct gcaccagatt cgacaggcgc ccttgagaga agtaggcagc
     1141 taactctgct gcgtctgtct tgactgcatc agatgggtca agatttcctg agatgacaac
     1201 atggcttcca ggaatgtcct tagcatggaa ccaaagttcc tccttgcggg ccattttaaa
     1261 ggtcaattcc tcattttgaa gattgtttcg tccgacatag atgatggttt tgccatcgct
     1321 tgctagatat tgttctagtt ttttgcgttt ctggattttc tcccgttgtc ttctgcggat
     1381 aaaacctgtt tgaatcaatt cttcacggat ttcagcgatt tcttccagtc cagcttggtt
     1441 gaggacggtt tctacacttt ccagatagag aatagtggct ttggtttctt caatcaaatc
     1501 agtcaagtat ttgacagctt ctttgagttt ctgataccgt ttaaaatagc gttgggcatt
     1561 ctggttggga gtcagagcct tatcaagcgc aatcatgata ggttggttgg tatagtagtt
     1621 gtctaggata acctggtctt ggtcgttagg cacttggtgg aggaaggttg tcagcaattc
     1681 tcctttttga cgaaattctt cagcgttgtc tgtcgccagt aactcttttt cctgtttttt
     1741 gagtttgtgt cggtttttct gaagttcatt ttcaacacga cgaatcagtt cactggcctg
     1801 ctgtttgacg cggtcgcgct cagccttatc cttatagtag gtgtccaaca aatcagaaag
     1861 atttgcaaga ggctctccca cctgatttgc aaaaggaact ggactgaagg aagtctcagt
     1921 caagcatggc ttggtttctt gattgaaaaa atttcggaaa gcggaaagtt tttcactaac
     1981 cagtatcctt tccaattcat ttgccgtatc gcgtcccaga ccttgaaaga ggctttgaag
     2041 attttttgct gttagttctt gggtttgcag gatttcaaag agcttttcat ccttgatagt
     2101 aaaaggattg agagattttg tacttggcgg agcgatatag gtcgatcctg gaagtaaggt
     2161 gcggtagcta ttttgtgaaa agccgacgtg tttgataact tcgaggattt tatgactgct
     2221 tttatcgacc agtagaatat tactgtgttt ccccataatt tcgataatca aggtagcctg
     2281 gatatggtct ccaatctcgt ttttattgga aactgtaatt tccacaatac ggtcattttc
     2341 cacttgctca atcgactcaa tcagggcccc ctgcaaatac tttctcaaaa ccatgataaa
     2401 ggtagaaggt tgggctggat tttcaaaagt cgtttgggtc agctgaatgc gtccaaaaac
     2461 tggatgggca gaaaggagca ggcgatggct ttggcgattg ctgcggattt gcaagaccaa
     2521 ctcttgttca aaaggctgat tgattttctg gatgcgacca ttcactaatt cgcttcgcaa
     2581 ttcctcaact atgtggtgta aaaaaaatcc gtcaaatgac atcgttctct ccttgtgatt
     2641 gtattccata gtattatatc aaaaaggtag aataaaatca tggaaatgtg gtataataaa
     2701 gccaagtaaa gagaaacgag aagcacatgt atattgaaat ggtagatgaa actggtcaag
     2761 tttcaaaaga aatgttgcaa caaacccaag aaattttgga atttgcagcc caaaaattag
     2821 gaaaagaaga caaggagatg gcagtcactt ttgtgaccaa tgagcgtagt catgaactta
     2881 atctggagta ccgtgacacc gaccgtccga cagatgtcat cagccttgag tataaaccag
     2941 aattggaaat tgcctttgac gaagaggatt tgcttgaaaa tccagaattg gcagagatga
     3001 tgtctgagtt tgatgcctat attggggaat tgttcatctc tatcgataag gctcatgagc
     3061 aggccgaaga atatggtcac agctttgagc gtgagatggg cttcttggca gtacacggct
     3121 ttttacatat taacggctat gatcactaca ctccggaaga agaagcggag atgttcggtt
     3181 tacaagaaga aattttgaca gcctatggac tcacaagaca ataaacgaaa atggaaaaat
     3241 cgtgacttga tatccagttt agaatttgct ttgacaggta tttttactgc tatcaaggaa
     3301 gaacgcaata tgcgaaaaca cgcagtgacg gctctagtgg tcatccttgc aggttttgtt
     3361 tttcaggtgt cacgaatcga atggctcttt ctcctattga gtattttctt ggtagtagcc
     3421 tttgagatta tcaactctgc tattgaaaat gtggtggatt tggccagtca ctatcacttt
     3481 tccatgctgg ctaaaaatgc caaggatatg gcggctggcg cggtattagt ggtttctctt
     3541 ttcgcagcct taacaggcgc attgattttt ctcccacgaa tctgggattt attattttaa
     3601 acagtaagag gaaattatga cttttaaatc aggctttgta gccattttag gacgtcccaa
     3661 tgttgggaag tcaacctttt taaatcacgt tatggggcaa aagattgcca tcatgagtga
     3721 caaggcgcag acaacgcgca ataaaatcat gggaatttac acgactgata aggagcaaat
     3781 tgtctttatc gacacaccag ggattcacaa acctaaaaca gctctcggag atttcatggt
     3841 tgagtctgcc tacagtaccc ttcgcgaagt ggacaccgtt cttttcatgg tgcctgctga
     3901 tgaagcgcgt ggtaaggggg acgatatgat tatcgagcgt ctcaaggctg ccaaggttcc
     3961 tgtgattttg gtggtgaata aaatcgataa ggtccatcca gaccagctct tgtctcagat
     4021 tgatgacttc cgtaatcaaa tggactttaa ggaaattgtt ccaatctcag cccttcaggg
     4081 aaataacgtg tctcgtctag tggatatttt gagtgaaaat ctggatgaag gtttccaata
     4141 tttcccgtct gatcaaatca cagaccatcc agaacgtttc ttagtttcag aaatggttcg
     4201 cgagaaagtc ttgcacctaa ctcgtgaaga gattccgcat tctgtagcag tagttgttga
     4261 ctctatgaaa cgagacgaag agacagacaa ggttcacatc cgtgcaacca tcatggtcga
     4321 gcgcgatagc caaaaaggga ttatcatcgg taaaggtggc gctatgctta agaaaatcgg
     4381 tagcatggcc cgtcgtgata tcgaactcat gctaggagac aaggtcttcc tagaaacctg
     4441 ggtcaaggtc aagaaaaact ggcgcgataa aaagctagat ttggctgact ttggctataa
     4501 tgaaagagaa tactaagtag aggtaggctc atgcctgctt cttgttttta cagaaggagg
     4561 acttatgcct gaattacctg aggttgaaac cgtttgtcgt ggcttagaaa aattgattat
     4621 aggaaagaag atttcgagta tagaaattcg ctaccacaag atgattaaga cggatttgga
     4681 agagtttcaa agggaattgc ctagtcagat tatcgagtca atgggacgtc gtggaaaata
     4741 tttgcttttc tgcctgacag acaaggtctt gatttcccat ttgcggatgg agggcaagta
     4801 tttttattat ccagaccaag tgcctgaacg caagcatgcc catgttttct tccggtttga
     4861 agatgggggc acgcttgttt atgaggatgt acgcaagttt ggaaccatgg aactcttggt
     4921 gcctgacctt ttagacgcct actttatttc taaaaaatta ggtcctgaac caagcgaaca
     4981 agactttgat ttacaggtct ttcaagctgc ccttgccaag tccaaaaagc ctatcaaatc
     5041 ccatctccta gaccagacct tggtagctgg acttggcaat atctatgtgg atgaggttct
     5101 ctggcgagct caggttcatc cagctagacc ttcccagact ttgacagcag aagaagcgac
     5161 tgccattcat gaccagacca ttgctgtttt gggccaggct gttgaaaaag gcggttccac
     5221 cattcggacc tataccaatg cctttgggga agatggaagc atgcaggatt ttcatcaggt
     5281 ctatgataag actggtcaag aatgtgtacg ctgtggtacc atcattgaga aaattcaact
     5341 aggcggacga ggcacccact tttgtccaaa ctgtcaaagg agggactgat gggaaaaatc
     5401 atcggaatca ctgggggaat tgcctcaggt aagtcaactg tgacaaattt tctaagacag
     5461 caaggctttc aagcagtgga tgccgacgca gtcgtccacc aactacagaa acctggtggt
     5521 cgtctgtttg aggctctagt acagcacttt gggcaagaaa tcattcttga aaacggagaa
     5581 ctcaatcgcc ctctcctagc tagtctcatc ttttcaaatc ctgaagagca aaaatggtct
     5641 aatcaaattc aaggggagat tatccgtgag gaactggcta ctttgagaga acagttggct
     5701 cagacagaag agattttctt catggatatt cccctacttt ttgagcagga ctacagcgat
     5761 tggtttgctg agacttggtt ggtctatgtg gaccgagatg cccaagtaga acgcttaatg
     5821 aaaagggacc agttgtccaa agatgaagct gagtctcgtc tggcagccca gtggccttta
     5881 gaaaaaaaga aagatttggc cagccaggtt cttgataata atggcaatca gaaccaactt
     5941 cttaatcaag tgcatatcct tcttgaggga ggtaggcaag atgacagaga ttaactggaa
     6001 ggataatctg cgtattgcct ggtttggtaa ttttctgaca ggagccagta tttctttggt
     6061 tgtacctttt atgcccatct tcgtggaaaa tctaggtgta gggagtcagc aagtcgcttt
     6121 ttatgcaggc ttagcaattt ctgtctctgc tatttccgcg gcgctctttt ctcctatttg
     6181 gggtattctt gctgacaaat acggccgaaa acccatgatg attcgggcag gtcttgctat
     6241 gactatcact atgggaggct tggcctttgt cccaaatatc tattggttaa tctttcttcg
     6301 tttactaaac ggtgtatttg caggttttgt tcctaatgca acggcactga tagccagtca
     6361 ggttccaaag gagaaatcag gctctgcctt aggtactttg tctacaggcg tagttgcagg
     6421 cactctaact ggtcccttta ttggtggctt tatcgcagaa ttatttggca ttcgtacagt
     6481 tttcttactg gttggtagtt ttctattttt agctgctatt ttgactattt gctttatcaa
     6541 ggaagatttt caaccagtag ccaaggaaaa ggctattcca acaaaggaat tatttacctc
     6601 ggttaaatat ccctatcttt tgctcaatct ctttttaacc agttttgtca tccaattttc
     6661 agctcaatcg attggcccta ttttggctct ttatgtacgc gacttagggc agacagagaa
     6721 tcttcttttt gtctctggtt tgattgtgtc cagtatgggc ttttccagca tgatgagtgc
     6781 aggagtcatg ggcaagctag gtgacaaggt gggcaatcat cgtctcttgg ttgtcgccca
     6841 gttttattca gtcatcatct atctcctctg tgccaatgcc tctagccccc ttcaactagg
     6901 actctatcgt ttcctctttg gattgggaac cggtgccttg attcccgggg ttaatgccct
     6961 actcagcaaa atgactccca aagccggcat ttcgagggtc tttgccttca atcaggtatt
     7021 cttttatctg ggaggtgttg ttggtcccat ggcaggttct gcagtagcag gtcaatttgg
     7081 ctaccatgct gtcttttatg cgacgagcct ttgtgttgcc tttagttgtc tctttaacct
     7141 gattcaattt cgaacattat taaaagtaaa ggaaatctag tgcgagtaaa aattaatctc
     7201 aaatgctcct cttgtggcag tatcaattac ctaaccagta aaaattcaaa aacccatcca
     7261 gacaagattg aggttttaaa gtattgtccc aaggaaagaa aagtaaccct acatcttgaa
     7321 tctaagtaga ttttatggta aaataatagg gattttaagg agtttgatat gtataaccta
     7381 ttattaacca ttttattagt attatctgtt gtgattgtga ttgcaatttt catgcaacca
     7441 accaaaaacc aatccagcaa tgtatttgat gccagttcag gtgatttgtt tgaacgcagt
     7501 aaagctcgcg gttttgaagc tgtaatgcag cgtttgacag ggattttagt ctttttctgg
     7561 ctagccattg ccttagcatt gacggtatta tcaagtagat aagaaaataa tgggcaggac
     7621 taggtctttg cctcttttta tttttaaagg atgtttgaga aggttttaca gtaaaagaaa
     7681 attaaaaaat ctagaaagaa aatatgaaag atagaataaa agaatattta caagacaagg
     7741 gaaaggtgac tgttaatgat ttggctcagg ctttgggaaa agacagttcc aaggattttc
     7801 gtgagttgat taaaaccttg tccttaatgg aaagaaagca ccaaattcgt tttgaagaag
     7861 atggtagtct gaaattagaa attaagaaaa aacatgagat taccctcaag gggatttttc
     7921 atgcccataa aaatggcttt ggctttgtta gtctggaagg cgaggaggac gacctttttg
     7981 tagggaaaaa tgatgtcaac tatgctattg ctggtgatac cgtcgaggta gtgattaaga
     8041 aagtcgctga ccgcaataag ggaacagcag cagaagccaa aattattgat atcctagaac
     8101 acagtttgac aacagttgtc gggcaaatcg ttctggatca ggaaaaacct aagtatgctg
     8161 gctatattcg ttcaaaaaat cagaaaatca gtcaaccgat ttatgttaag aaaccagccc
     8221 taaaattaga aggaacagaa gttctcaaag tctttatcga taaataccca agcaagaaac
     8281 atgatttctt tgtcgcgagt gttctcgatg tggtgggaca ctcaacggat gtcggaattg
     8341 atgttcttga ggttttggaa tcaatggaca ttgtatccga gtttccagaa gctgttgtta
     8401 aggaagcaga aagtgtgcct gatgctccgt ctcaaaagga tatggaaggt cgtctggatc
     8461 taagagatga aattaccttt accattgacg gtgcggatgc caaggacttg gacgatgcag
     8521 tgcatatcaa ggctctgaaa aatggcaatc tggagcttgg ggttcacatc gcagatgttt
     8581 cttattatgt gaccgagggg tctgcccttg acaaggaagc ccttaaccgt gcgacttctg
     8641 tttacgtgac agaccgagtg gtgccaatgc ttccagaacg actatcaaat ggcatctgct
     8701 ctctcaatcc ccaagttgac cgcctgaccc agtctgctat tatggagatt gataaacatg
     8761 gtcgtgtggt caactatacc attacacaaa cagttatcaa gaccagtttt cgtatgacct
     8821 atagcgatgt caatgatatc ctagctggcg atgaagaaaa gagaaaaaaa tatcataaaa
     8881 ttgtaccaag tatcgaactc atggccaagc ttcatgaaac tttagaaaac atgcgtgtga
     8941 aacgtggagc tctcaatttt gataccaatg aagcgaagat tttagtggat aaacaaggta
     9001 agcctgttga tatcgttctt cggcagcgtg gtattgccga gcggatgatt gagtctttta
     9061 tgttgatggc taatgaaaca gttgccgaac atttcagcaa gttggatttg ccttttatct
     9121 atcgaattca cgaggagcct aaggctgaaa aggttcagaa gtttattgat tatgcttcga
     9181 gttttggctt gcgcatttat gggactgcca gtgagattag tcaggaggca cttcaagaca
     9241 tcatgcgtgc tgttgaggga gaatcttatg cagatgtatt gtccatgatg cttcttcgct
     9301 ctatgcagca ggctcgttat tcggagcaca attacggcca ctatggacta gctgctgact
     9361 attatactca ctttaccagt ccaattcgtc gttatccaga ccttcttgtt caccgtatga
     9421 ttcgggatta cggccgttct aaggaaatag cagagcattt tgaacaagtg attccagaga
     9481 ttgcgaccca gtcttccaac cgtgaacgtc gtgccataga agctgagcgt gaagtcgaag
     9541 ccatgaaaaa ggctgagtat atggaagaat acgtgggtga agagtatgat gcagttgtat
     9601 caagtattgt caaattcggt ctctttgtcg aattgccaaa cacagttgaa ggcttgattc
     9661 acatcactaa tctacctgaa ttttatcatt tcaatgagcg tgatttgact cttcgtggag
     9721 aaaaatcagg tatcactttc cgagtgggtc agcagatccg tatccgtgtt gaaagagcgg
     9781 ataaaatgac tggagagatt gatttttcat tcgtacctag tgagtttgat gtgattgaaa
     9841 aaggcttgaa acagtctagt cgtagtggca gagggcgtgg ttcaaatcgt cgttcggata
     9901 agaaggaaga caagagaaaa tcaggacgct caaatgataa gcgtaagcat tcacaaaaag
     9961 acaagaagaa aaaaggaaag aaaccttttt acaaggaagt agctaagaaa ggagccaagc
    10021 atggcaaagg gcgagggaaa ggtcgtcgca caaaataaaa aggcacgcca cgactataca
    10081 atcgtagata cgctagaggc agggatggtc ctgactggaa ctgaaatcaa gagtgtacga
    10141 gctgctcgaa ttaatctcaa ggatggcttt gctcaagtga aaaatggaga agtttggctg
    10201 agcaatgttc atatcgcgcc ttacgaagag ggcaatatct ggaaccagga accagaacgt
    10261 cgtcgtaaac tcctgctcca taaaaggcaa attcaaaaat tggaacaaga gaccaaaggg
    10321 acaggaatga ccttagttcc ccttaaggtc tatataaaag atggctacgc taagcttctt
    10381 ttaggacttg ccaaagggaa gcatgactat gacaaacggg agtctatcaa acgtcgtgag
    10441 caaaatcgag atatcgcgcg tgtgatgaaa gctgttaatc agcgataaaa agaggaattg
    10501 aaaatggaaa aattagttgc ctataaacgc atgcctttgt ggaataaaca aacaatgcct
    10561 gaagctgttc agcaaaagca caatacaaaa gttgggactt gggggaaaat tactgtcttg
    10621 aagggagctc tcaagtttat tgaattgaca gaagaagggg aagttctagc tgaacacctc
    10681 tttgaagcag gggcagacaa tccaatggcc caacctcaag cctggcaccg agtggaagct
    10741 gccacagatg atgtggaatg gtacttggaa ttttattgta aacctgagga ttattttgct
    10801 aaaaaataca ataccaatcc tgttcattca gaggtcctag aggccatgga gacagtgaaa
    10861 caagggaaag ctttggattt gggttgtggt caggggcgta attctctttt tctagcccag
    10921 caagattttg atgtgacggc tgtagatcaa aatggactag ctcttgaaat cttgcaaagc
    10981 attgtggagc aggaagattt ggacatgcct gttggccttt acgatatcaa ttcagctagc
    11041 attgaacaag aatatgattt tatcgtttca acagttgttc tcatgtttct acaagcggac
    11101 cgcattccag ctattattca aaatatgcag gagaaaacca gtgttggtgg ttacaacctt
    11161 atcgtttgtg ccatggacac ggaggattat ccttgctcgg ttaacttccc attcaccttt
    11221 aaagaaggag aactggcaga ctattacaag gattgggaat tggttaagta caatgaaaat
    11281 ccaggccatt tgcaccgtcg cgatgagaat ggcaatcgta ttcaactacg ctttgcgacc
    11341 ttactagcta agaaaatcaa gtaaacacac atgaagatta ggaattttcc tgatcttttt
    11401 tcttttttac gaatgatata gaaaaggagg gaattcatgt ttgttgcgag agatgctagg
    11461 ggagaattgg taaatgtgtt agaggataaa cttgagaagc aagcatacac ctgcccagct
    11521 tgtggaggcc agctccattt gcgtcaagga ccaagtgtac ggacgcattt tgcccataaa
    11581 tccttaaaag actgtgattt tttctttgaa aatgaaagtc cagaacacct ggccaataag
    11641 gaatccctct atcactggtt gaaaaaagag acaaaggttc aattagagta cccgctttca
    11701 gaacttaaac agattgcgga tgtatttgta aatggcaatc tagctctaga agttcagtgt
    11761 agtcccttgc ctcagaaagt ccttaaagag cgaagtgagg gatatcgtag tcagggttac
    11821 caagtactgt ggttgctggg tcaaaaactg tggctcaagg agcgtttgac tcgtctacag
    11881 caaggttttc tttatttcag tcaaaacatg ggcttttatg tttgggaatt agacaaggaa
    11941 aaacaagttt taagactcaa atacctgatt taccaggatc tccgcggtaa actccattat
    12001 caaatcaagg aattttccta tggtcaaggt agtttattgg aaatattgcg tcttccctat
    12061 aagagacaaa aaatatctca ttttacagtt tctgaggaca aggacatctg tcgctatatc
    12121 cggcaacaac tttattatca aaatctcttt tggatgaaag aacaagcaga agcctatcaa
    12181 aagggagaaa atatcctgac ttatggactg aaagaatggt atccacaaat tcgaccaata
    12241 gtgggcaaat ttttccagat tgaacaagac ttgactagct attatcagca cttttatacc
    12301 tattaccaaa aaaatcctca aaatgattgg caaaagcttt atccaccagc cttttatcag
    12361 caatatttct tgaaaaatat ggtagaatag aaaggatgga ggaatctaat ggtattacaa
    12421 agaaatgaaa taaatgaaaa agatacatgg gatctatcaa cgatctaccc aactgaccag
    12481 gcttgggaag aagccttaaa agatttaaca gaacaattgg agacagtagc ccagtatgaa
    12541 ggccatctct tggatagtgc ggataaccta ctagaaatca ctgaattttc tcttgaaatg
    12601 gaacgccaga tagagaagct ttacgtttat gctcatatga agaatgacca ggatacacgt
    12661 gaagctaagt atcaagagta ctatgccaag gccatgacac tctacagcca gttagaccaa
    12721 gccttttcat tctatgagcc tgaatttatg gagattagcg aaaagcagta tgctgacttt
    12781 ttagaagctc aaccaaagct gcaggtttat caacactatt ttgacaagct cttgcaaggc
    12841 aaggatcacg ttctctcaca acgtgaagaa gaattattgg ctggagctgg agaaatcttt
    12901 ggttcagcaa gtgaaacctt tgctatcttg gacaatgcgg atattgtgtt cccttatgtc
    12961 ctagacgatg atggtaaaga agttcagcta tctcatggga cttacacacg tttgatggag
    13021 tctaaaaaac gtgaggttcg tcgtggtgcc tatcaagctc tttatgcgac ttacgaacaa
    13081 ttccaacaca cctatgccaa aaccttgcaa accaatgtta aggtgcaaaa ttaccgtgct
    13141 aaagttcgta actacaagag tgctcgtcat gcagccctcg cagcgaattt tgttccagaa
    13201 agtgtttatg acaatttggt agcagcagtt cgcaagcatt tgccactctt acatcgctat
    13261 cttgagcttc gttcaaaaat cttggggatt tcagatctca agatgtacga tgtctacaca
    13321 ccgctttcat ctgttgaata cagttttacc taccaagaag ccttgaaaaa agcagaagat
    13381 gctttggcag tcttgggtga ggattacttg agccgtgtta aacgtgcctt cagcgagcgt
    13441 tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg cctactctgg tggttcttac
    13501 gataccaatg cctttatgct tctcaactgg caggacaatc tggacaatct ctttactctt
    13561 gttcatgaaa caggtcacag tatgcattca agctatactc gtgaaactca gccttatgtt
    13621 tacggagatt actctatctt tttggctgag attgcctcaa ctaccaatga aaatatcttg
    13681 acggagaaat tattggaaga agtggaagac gacgcaacac gctttgctat tctcaataac
    13741 ttcctagatg gtttccgtgg aacagttttc cgccaaactc aatttgctga gtttgaacac
    13801 gccattcacc aagcagatca aaatggggag gtcttgacaa gcgatttcct aaataaactc
    13861 tacgcagact tgaaccaaga gtattatggt ttgagtaagg aagacaatcc tgaaatccaa
    13921 tacgagtggg ctcgtattcc acacttctac tataactact atgtatatca atattcaact
    13981 ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc atggtagtca agaagaccgt
    14041 gaccgctata tcgactacct caaggcaggt aagtcggact atccacttaa tgtcatgaga
    14101 aaagctggtg ttgatatgga gaaggaagac tacctcaacg atgcctttgc agtctttgaa
    14161 cgccgtttaa atgagtttga agcccttgtt gaaaaattag gattggcata aaatggttga
    14221 atcgtatagt aagaatgcta accataacat gcgtcgtcct gtcgtcaaag aagaaattgt
    14281 agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc ttgaaagaat tggaagactt
    14341 tgcccgcaag gaaaatattc ctattattcc ccatgaaacg gttgcttatt tccgttttct
    14401 tatggaaacc atgcagccta aaaatattct ggaaattggg acggctatcg gtttttcagc
    14461 tctcttgatg gctgaacatg cgccaaatgc taagattaca actattgatc gtaatccaga
    14521 aatgattggt tttgccaagg aaaattttgc ccagtttgac agtcgcaagc aaatcactct
    14581 cctagaggga gatgcggtgg atgtcttatc tacactgaca gagtcttatg atttcgtctt
    14641 tatggattct gccaagtcta aatacatcgt ctttctgcca gaaatcctca aacatttgga
    14701 agttggtggt gtggttgtct tggatgatat ttttcaaggt ggtgatgttg ccaaggatat
    14761 tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc cttcaaaaat tatttgatgc
    14821 aaccttagac aatccagaac tcaccgcaac attagtgcct ttaggagatg gtattctcat
    14881 gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc gaatgatttt cagaaaaatt
    14941 taagaaaaaa tagtaaaata gatagagtaa cacttatctc aaaggagtag acatgaagaa
    15001 aaaattattg gcaggtgcca tcacactatt atcagtagca actttagcag cttgttcgaa
    15061 agggtcagaa ggggcagacc ttatcagcat gaaaggggat atcatcacag aacatcaatt
    15121 ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc ttgttaaata tgaccatcca
    15181 aaaagttttt gaaaaacaat atggctcaga gcttgatgat aaagaggttg atgatactat
    15241 tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt gtcttgtcac aagcaggtat
    15301 gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa ttagttgagt tggcagttaa
    15361 gaaggtagca gaagctgaat tgacagatga agcctataag aaagcctttg atgagtacac
    15421 tccagatgta acggctcaaa tcatccgtct taataatgaa gataaggcca aagaagttct
    15481 cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta gccaaagata attcaactga
    15541 tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat tctgcttcaa cagaagtacc
    15601 tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat ggtgtttctg atgtgattac
    15661 agcaactggc acacaagcct acagtagcca atattacatt gtaaaactca ctaagaaaac
    15721 agaaaaatca tctaatattg atgactacaa agaaaaatta aaaactgtta tcttgactca
    15781 aaaacaaaat gattcaacat ttgttcaaag cattatcgga aaagaattgc aagcagccaa
    15841 tatcaaggtt aaggaccaag ccttccaaaa tatctttacc caatatatcg gtggtggaga
    15901 ttcaagctca agcagtagta catcaaacga atagtccaaa tcaatgagtc agggaaaaaa
    15961 actcgacttc aggaaaaaat gaagcaaaca ttcccacaat aaaacgcata gtacaaggtt
    16021 tgtactgacc ccaaaagtta gacaattaat ttatctgaag gatttagttc tgtattgcac
    16081 agggctaagt ccttttagtt ttaccttaat tctcttattg ttgtaataat caatatagtc
    16141 tataatggct tgttccaatt gattaagtga tttaaatgtt tgctcatagc cataaaacat
    16201 ttcggatttt aaaatgccaa agaaagattc catcctatcg ttgtcttggc tgtttccttt
    16261 gcgtgacata gatgcttgaa ttcccttact ctctaggaag caatgataag aatcgtgttg
    16321 gtattgccag ccttggtcac tatggagaat cgtattctcg tagtgcttct ctttgaatgc
    16381 ctgttccaac attaacgatc aatcaattta atcatgtacc taatattaga attgtttatc
    16441 ccaaatttat ttgaa
//
LOCUS       DAVBNZ010000049        15964 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000049 DAVBNZ010000000
VERSION     DAVBNZ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15964
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.049"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(<1..1205)
                     /gene="dcm"
                     /locus_tag="VQ860_001641"
     CDS             complement(<1..1205)
                     /gene="dcm"
                     /locus_tag="VQ860_001641"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET3120039.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARKSYKSIFQT
                     EGEIEFHDIRDVSDAEFKKLRGKVDIICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQLLNSKDFGVPQNRE
                     RVFIIGHSRKRGTRLLFPFRREGQTTNSETLKTLGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLDKRQNGRRFKENQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYHVAGVLIDGQFYRLRIRR
                     ITPKECFRL"
     gene            complement(1304..2083)
                     /locus_tag="VQ860_001642"
     CDS             complement(1304..2083)
                     /locus_tag="VQ860_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3120040.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKILKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQVENETAPVSHSAPRETEVSETKYSE
                     TDSLFIEDEEDRNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            complement(2080..2253)
                     /locus_tag="VQ860_001643"
     CDS             complement(2080..2253)
                     /locus_tag="VQ860_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120041.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVQLES
                     SGDLTLKELGGAL"
     gene            complement(2783..7996)
                     /locus_tag="VQ860_001644"
     CDS             complement(2783..7996)
                     /locus_tag="VQ860_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3120042.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(8040..14519)
                     /locus_tag="VQ860_001645"
     CDS             complement(8040..14519)
                     /locus_tag="VQ860_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3120043.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVSGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVEPEKVEALKEYTGKIEQPS
                     AEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHN
                     FINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVI
                     KLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQ
                     YQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVY
                     DELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENY
                     FMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKT
                     QQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVGT
                     NNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHA
                     DGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLID
                     KSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLW
                     DPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDEI
                     LTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEK
                     VYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVPMKDKEVISDINKNKSSIN
                     KLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALN
                     SVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKV
                     IDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNV
                     IELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQT
                     KAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFII
                     ANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEK
                     LYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGD
                     AFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPN
                     DPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAV
                     AKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIIT
                     RRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMV
                     PYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKERED
                     KFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRV
                     LKLKKAIFKAYLDQTGDFRSSIFENKK"
     gene            complement(14728..15906)
                     /locus_tag="VQ860_001646"
     CDS             complement(14728..15906)
                     /locus_tag="VQ860_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120044.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         4495 a         3249 c         2393 g         5827 t
ORIGIN      
        1 tgcagtcgaa aacactcttt aggagtgatt cgtcgtattc tcaaacggta aaattgtcca
       61 tctattaaaa caccagctac atggtaaact tgtttatctt ctccttcata gctagccact
      121 actactccca tttgaccact agttgttaat gtattcgcta taccttttcc aactctacca
      181 cgacgatact gagaacttgg tctttctaaa ttgattgaat ctccaatctc tgcttgagca
      241 tacccttttt tagttgcttc ccggactttt agaaattgga ttggttctgg aatcagtatt
      301 ttgggaattt tatctcctcc ttgcatcgta gtcagtgttg gagataagcc ctcgcttcca
      361 tagactcgac ctgtctcctt aaagctagtc ggtaaatctc caacaacgac aataccatga
      421 cgatcctgag tatttaaagt aaacatcggc tcttggtttt ccttaaagcg tctcccattt
      481 tgtctcttgt ctaatctgtc tggtgtcata caaggaatcg caaccttgaa tccttctcct
      541 tttccacgaa ctaaggttgg tgcaagacct tctgaataat agactttacc gctcattcca
      601 ctttttgatg gattcaaatt ccctagtgtt tttaaagtct cagagttagt tgtttgacct
      661 tctcgtctga aaggaaataa gagtctggta cctctctttc tagaatgtcc gataataaac
      721 accctctctc tgttttgggg aacgccaaaa tccttactgt taagcaactg ccactcaaca
      781 tcaaacccca actcatcaag tgtggtaagg attgtggtga acgtccgtcc cttatcgtga
      841 ttgagtaggc ctttaacatt ttcaagaaaa agaaaacgtg gttggatttg tttggccgcc
      901 cgagcaattt caaagaacaa agttcctcta gtatcttcaa atcccaatcg tcttcctgcg
      961 attgaaaatg cttgacaagg gaatccccca cagatgatat cgactttccc tctaagtttt
     1021 ttaaattctg catctgaaac atctcgtatg tcatgaaatt ctatttctcc ttccgtttga
     1081 aaaatggact tataagattt cctagcaaat ttatcaatct cacaaaatcc aatacactcg
     1141 tgtccaacac tttccattcc aagtcgaaat ccacctatac ctgaaaataa atcaataaat
     1201 ctcatttctt gatcacctct ttcttatcga ctaccattgt cataactgtc actccacttg
     1261 aaatgacaat aagcataact aatatccact cgattgacga catttaacca cctccttttc
     1321 taacacggtt attccaaaca gaatacaggc cattaaacac aaattcagca agtacttccg
     1381 ctcgtctaac aaagcgaaca ttgtcaagag catactgata gattctttca aaatcagtca
     1441 tagcaatttc actggctgtt tcagaaaaac cttctcgtct aaattgatct tgtaccaatc
     1501 cccaaatata atctcgatca tattttgtga ccttttctac ttttcttttc aaaataggtt
     1561 gagtattcct atcctcctca tcctcaataa ataaagaatc agtctcacta tatttagtct
     1621 cactaacttc agtctctcta ggggctgaat gtgagactgg ggccgtttca ttttcaacct
     1681 gccctagtct ttttttaaca ctaggcctgt ttgaattacc tactggggta gaagataatt
     1741 cccctaaata aatcttatta gctagtcttc ctttctcact tgaagactgt tgaacttcat
     1801 caattaagtc atattcttta agaatttttt tgatagacag taattttgac ttcgagcaac
     1861 ctaacagctt catcagttta gaattagaaa atactaaata aaccgctcct tcttcatcta
     1921 tccaaccacg actgagagat aattctaaac gatcttttaa aatagaataa gccaccttta
     1981 cttctagttt catatccata tatttctcat cctcaaaaag aattttaggt aatttgtaat
     2041 accgttctga agtttggtat tgatttgcgg taattcgttt catagcgcac ctccaagttc
     2101 tttgagtgtt aaatctccgc ttgattccaa ttgaaccaag ccactttttt ccaattcagc
     2161 cataagagag atggcttcaa caatgtcaat tcccatttca cgtactaaaa atgaaatgac
     2221 aatatagcgt gatgattgta attcttttgt cattttccct cctgaaaata aaaaaaacgg
     2281 aaagattgtg aaattccttt ccgtaacata ataaatattt gaacaccaaa ctcaacacca
     2341 aaaaaatgtt tttattgata attattgctc aatcaagcac ttataacaat gtaaaaaata
     2401 aaaatctgta ctcacaaaaa cccttgaaat tcaagggttt taagcattta ttctacttca
     2461 caatgtttta ttattttaaa tcttctagac caaccattga atagtagcca ttgagttttt
     2521 tcctttcgta gcaaggattt agatccccta ttttatttta ctatagtttg aacatagaga
     2581 gttttcaaat gaatgatgtc caaacagttc ttgttttatg acatagaaat ctactttata
     2641 ttatatcatg ccttctttat tttgtccgat gatagccttt taccctatct tttagcctat
     2701 cttttaccct atatagaaaa aagccatcaa atgatgactt ttcagaggga gcaaaaaact
     2761 gttccttcta tattctaaac atttaaatgt cttctttaaa cagtttatta aagaaaccgt
     2821 ctgtgttttt aagaagggct ttgaagacct tagatttaag agcaacagtg tgagagaagt
     2881 catctggttt cttcaaatct tcttcaactg ctttatcaaa taaaggcctt aactcatcat
     2941 agttactgat atggacgcca tcaatatcga tagcctcaaa acctttctta gctttagcaa
     3001 gaacttcccc gtaccaatgt ctcttccact cttcaagagt attaaagttt cctttcgata
     3061 ctttattaat tattagctta tcgcttagta aaccgtggtt gtttttatct gcttctgctt
     3121 tgtatttatt tgatacataa ctaataaagc cattttcata accataatag ccccacatac
     3181 ggaaagcatt gtgcttaaat gataatgaac caggagcacc ttgactcgta ttcccaccgt
     3241 aaattcctgc catcatattg acatttacgt aagctgagtt tggtgtaaaa tcttctggtc
     3301 tataacgtcc attacctgga tttccatgtt ttgtcatgaa gttattatcc actaaatcat
     3361 tgacgctaga taaagtcatt accttttctt catctttcaa atcacggata ctatcccatt
     3421 ggtttggacc taaaagatca ttatactgaa tcttagagcg catttctttg tcaatcttct
     3481 tgaaccactt actattgtct cctttaattt taggaagtac agcatcagct tctacatgat
     3541 caagcaacat catagcttca ttgtagtttc tcatgtagcg gtcaatgtca tcacgtgtct
     3601 ttaatttgtc aggatctggg ttgtaccatt ggttaccatc atttggacga tggtaagcca
     3661 tgttaattcc aagtgcgccg tattcaccat tagtcgttga gctgtcaggt gtttgcaaca
     3721 taccttgagc ataggcttca acgtctgtac cttgacgatg cttatgacca ccgaagtaaa
     3781 gcattctatc gtttacgtgt gttgtttcgt gagtaaaggc tgaaatacca aatgggctaa
     3841 tcatatccgt caccataaac aagaccttgt catcattatt tggattaggg aatattgatg
     3901 ccatagcgcc catacgccag tctctatcat ggtgtcgcca tgttggacca tataattcac
     3961 gaattggagc tatagggtta cctttactgt caaatcctcg acgacctaca ggagaaccat
     4021 tgtaggtctg gttatcccaa actggtgtcg gtaccatatt ttgactctta agaagtctat
     4081 cacgaacatt aggcagagct aatctggacc agaaatctaa ataagtttgt tgagcatgtg
     4141 caacttcatc aatcttagtt ttgaactcat tacgagcttc ttctgtatgt tttccatatt
     4201 tctcaaatga actgtacgcc atcgtgttat atgttgaaat taagaacata tgggcatctt
     4261 taagcgttag aagtggtaaa atcatacgac catgaacacc gttatctaaa ccatcgaaca
     4321 cacgatgacg tttatctttc aactctgtat ttgttgtctt aggttctgaa acataaacat
     4381 tcttagctga gtggataaac caatcattga tgtctttatc ctctgtaaac agacgcatgt
     4441 tgtattctaa gaagttacgc aaattacttt taccagtatt acctgcgatg atttcacggt
     4501 aagcatcctg agtccgatcc cctttcaagt tcttttcact tgaaccgatg ttgatgagtc
     4561 tgtcaataac acttggtgtt ttaccataaa aatcaggttt gaacatcatg atgtttttta
     4621 tacttatgtc accgtatttg atatcatagt aacgattgag ataagtcaga gccatcatga
     4681 ttttagcttt attggtttcc actttcttga gaagtgattt tatcgcagct tcatcaccat
     4741 tcaattgatg gtcttcattt tcgaccaagg atttgactaa cttatctaga ttttgcttca
     4801 cttcggcaaa gctttcttct aagtatagat ctttaatata accattctta cgttcatccg
     4861 tattctctgc aggtttatca cgtctactca ttaaatctct tacttcttgt gaaatcaatt
     4921 ccacacttga taattgagat ttaacatcag caatcaattt atcacgattt ttaacaacca
     4981 tattcggtgt ataaacaaca tcaccaagac cagatacact atattcacgc acttgttgga
     5041 ctttagaatc agtattctta gtaacatcca tttcttcctt agtaccatca gcatagtgaa
     5101 ccataatctt atcaatatct gataaatcgg tcacgaattg accatccttc atccccgtaa
     5161 cagaaaggac ttctttctta gctaagtttg aatcttctgc aagtttgtta ccttggttga
     5221 caatccattc tttattataa aatggttgaa gtttctcaat attacgataa gctaaatcac
     5281 gttcggattt gtagtcttga gttgacttat attcatcttc tcttctggtt aaacgattta
     5341 agcgattgac cacaggttcg ttgatttcgt atttatcagc agtaagtcca aaatttgcaa
     5401 ttctcttatt agcttcatct tgactaattt ctttaatttt gtcacgagaa cgtttgtatg
     5461 aatgcttacc tgaactgaca cctttgacaa caaagttacg ctctaaccag ccatttgtga
     5521 aataaccacc atcgtagtcc aaatcggaag aaccaaagaa ctcttcacca ttttcaactc
     5581 tcatcattga aatattatct tcaagtttac caaaaggaag attgctattg ataaatccac
     5641 ctgtttcaaa caaaacttta gtcttaatgg ttcctttggt gactgattta cgaattgaac
     5701 cgtatttacc aattcccata gagtcgttac cattatctgt tttagcaact aaaccaccta
     5761 tacgggctct gttagcaaca atatcagcct cgacatatgc ttttgcaaga ttacctctcc
     5821 aaatctcacc ggcaatgcca gccatatatt gacctttatc accaacacct gtaagattac
     5881 cgatgaaggc tacatttgtc aactgaccac cactatcgat tttattgacg atacccgcaa
     5941 tattgttatt agcaactaca ttaccagtta ccttaacatc ttcaacagtt gcatttttca
     6001 ccatattggc aacaggtgct attccgtcag cccaaggcat attgatatcc acattaccta
     6061 aattaatatt tttcacagaa ccattttcaa cacggtcaaa taagggacgg gcaatgttat
     6121 gaattgtata ttgtttacca tcaacacttg atagatgtcc cttaaacgta cctggaacat
     6181 attgtttgtt aggtgttggt acattcgttg cattcaaatc tgctccgatt ttaaatgtac
     6241 catttttatc agcattcatg gcatctacta actctttaaa gttataataa acgtcatcaa
     6301 cttttggaac tggtttttca atataatgaa catacttgtt acgaaccttc gttgggtctg
     6361 tatgttgaat caaatcttga gcttcggcag tgattttata aagtttctta ccttcttcag
     6421 tcacttcttc aattttatca actgctaaac gtgttacttt attatcacga ctagtaattt
     6481 ttaagtacat tttcttcaca tcttcatctg aaggtttttc agtcataaaa tcactaggtg
     6541 tttcagtacc atcgtcattt accttcacta aattagtaga tgcgatattt ttaatttcaa
     6601 cttttttcaa atccaagcga agtggtttct cttctaatgt tgcagtttct tctcccttgc
     6661 cacggtcata ggtcatagtg gtctctatct tatagtcctt gtagaatttt aaatcttcta
     6721 cctgcttatc taattgctct gaagtcaaat ctactgtttt gacaatttca tttccatctt
     6781 taattgtcgc agtaatttta ttgattgtga ctccatctgt attaactaaa tgataagaaa
     6841 gagttgcgga tcggtttaat acatttgtat ttgttctatc taaggtcaaa acaggagccg
     6901 ttttttcttt aggtttttct ttggtacctt ttacaagaat tttaggcttc atttctttca
     6961 aaatagttac tgtttcaact gggtcactga tttttttgcc atgtaactct tcatagctag
     7021 taacaatttg acgttcgcca tcctcaccaa cttgtctaac agaatcatcg cctataaatt
     7081 tgctaggatc agattcttct atagtggttt taggaatagt ctctgtccga atatcggtat
     7141 gtaaagaagg caactcttct ctttctgatg caacttctga aactgtagat attggttcag
     7201 tatactctgg aatgtcgcta acaggtggct caatcaagtt tccattttca tccactcctg
     7261 ttgtacctac tggctcagta tattctggga tgtcgttaac aggtggttca atcaagtttc
     7321 cattttcatc tactcctgtt gtccctactg gttcagtgta tgctagtttc tcatgaactt
     7381 caggctcaac aaggtttgca cctattggtt gcgtatagtc aggcttctca tgaacttccg
     7441 gttcgccttt ctctgttaca actttgggtt gctcaactgg cgaaacagtt gatgctggag
     7501 aaaccgacga aacagtttta tcatcaagct ccaagtaacc aacatatctg taaccagaaa
     7561 tttgcaacac accatcacgt ccagactcat ggatgttagc attcaaatta agtgctgaag
     7621 cagttgatag tgtaactaaa cctgtcgccc ctacaatcaa aaatgtagct atttttttat
     7681 ttctattatc ttttgtgata atcacaataa gactcccgat agctaacaaa cccaatgcag
     7741 tcataataga ttgagaactt cctgtgtttg gtagtgcgtc tttttcataa tccaaagcat
     7801 atgactcttt ggattcatca ggtctacctt gtttgagttg atcacgttca gtttgtgtca
     7861 aactactata atctaagtaa tgataagtcg atgcaccaac aactgacggt gcaaataaaa
     7921 gactccccaa gaataccgaa ccaacaatac cctttatttt ccgaatggaa aatttatctt
     7981 tttttaataa tgacaattct aatcctccac cttcactttt tatttcctaa tagtaaacac
     8041 tattttttat tctcaaaaat tgaacttcta aaatcaccgg tttggtcaag ataagcttta
     8101 aagattgctt ttttcagttt aagaactcta ctatttgtct caggatataa tttggcaact
     8161 tcatcctcag catcaaattt tactgcatct tcaatcattt tttcaagtct attaatatta
     8221 tcaatagtca ctttctgttg tcgagcccaa gaaccgtttg gatcgataaa actaacttta
     8281 tttaactttc caaatttatc ttctctttct ttatacatat ctttcttgaa atctatccaa
     8341 gaattatact ggttattaaa tacttttgaa agaacaattt catcagtaac taaacctatt
     8401 tgtttaccat atgatgtaat aacttttcct tgagctttcg cttctttttc atactgatta
     8461 gaaatatatg gaaccatacc gtctttgtac cccttggctg ccaataactc aaatgcaata
     8521 cgtcgtccca ttaaatctcc tggtgttcct attttactgc tcaatgctga ataaattggt
     8581 gagaatagat taattgtata gtagccattc cgcttataag ttgcttcatc tacataacct
     8641 cttcttgtta taatatcatg ttctatcaaa ctgttaaatg tagttaattt agtaagttct
     8701 tctggtttta atctacgtac aacattcgtt gcataaacag aatttccatc aggatcaggt
     8761 ttatattcat tttctatttt tcttaataaa tcatattttt gatttgtatc taatttagct
     8821 acagctttac cttctagtat ttcaagcatg tatattacat caaacatatt atgcatatac
     8881 ttatttagat catcaacact tccaaatcgt tgagttggat ctgctacttg aagccttgtt
     8941 gattcttctg attgatcata ttttaatatg gaattaatag tgactgttgg atcattagga
     9001 tgatcaggag cttgtagcag tcctttagca taaaactctg gtccaagtcc atttcgtctt
     9061 ccatagcctc caagataaat ttctctatct gagttatgtg tcatttcgtg tgtataagtt
     9121 accgcaccat ctttatcaag catgcgatat gccatataat agaatgcatc ccctgtagca
     9181 tatgctccat tagaattatg aacaacatta tttcccgctg gaccgaagaa atgttttata
     9241 gctggatgat tagtttcaaa agttgcttga tatgtatctt tatcttcttt ttcatctgta
     9301 ccaaatctaa atgcatcata gactagaaca cttctatata atttttcttt atttttatca
     9361 tctagtattc tataccaata atcatagtga tctctaaatc taacagccgc ttctttagct
     9421 tttttctcaa catagtcatt taaatcagtt cctgctggat gttctttact tctatatcta
     9481 tcataagcac cgaaacctat agtcgaaatg ttggctataa taaacaccga tttttcaggt
     9541 aatgttaata gcggcaacac catacttgga tatttccaag atgggctagt taatctatca
     9601 tatactccaa ttgaatatgg actaccagct attgattgct tatcacttac ctctttaata
     9661 gtagattttt cttctacaat atatgcttta gtttgttctt taaaccactc attatttgtt
     9721 ttatctggta caaatgcttt tctatatttc tctaatgcat caaataaatt attagtctta
     9781 taatttttcg ctaataaaac attataagtt ataacattat tttttgctag taagttatta
     9841 tatcccgatt tacctagttc gataacatta tctaacgctg aactatttga tttaccgaag
     9901 aaatccaagt ggtacatgac taaatctttc gcttttgtat cacgatattt gaagtcgtac
     9961 caacgctcta agtatgttaa tcctagaagt aaagcttctt tattattttt aattttctcg
    10021 attacataat tatctattac cttattgtta ttttcagcta ttgcagcatc tgcagtaaga
    10081 agttttgtca aactatcttt caaattagtt tttgtggtat tgaattgttc ttctaaatat
    10141 aactccgtta aactaacatc cttagaaaca tctaatactt ttctaattgc ctctgattta
    10201 tattctacac tatttaatgc tggtaatact tcatctaaaa tattttgata attgcgaagt
    10261 aatgtattcg gtgtataaat taagtttgta ccgcctattc tatactctgc tacatttgaa
    10321 aaatcagttt gataatttac attaagtgtc tctgatgtat tatccgcgta atatagtaat
    10381 agtttattta tacttgattt atttttgtta atatcactaa ttacttcttt atctttcata
    10441 gggactactg acaataattc tttattataa agattactac ttgtctctac taaatttccg
    10501 tacttaacaa ttgtttctct attataaaac ggtaatagtt tttcaatatt tttatatact
    10561 ttttcttttg atgaatcagc attctcaaga tttttatagt cagttacata tctagaagag
    10621 aaattaaaat cttctgtttt aatagtattt ttagatacaa aagtagcttt tttctctttt
    10681 atttgtgcat cttctaatac ttctcctctt tgaacagtag aatccttagt taagatttca
    10741 tcatcttctt gtactacgtt cacaacctta ttatttttat tactgtatgt gccatttgct
    10801 tttataccat taaaattata acctgcaata gcattaccat tcgttacatt aacatcgctt
    10861 agtacattag aaagtcgacc ggatttttct aatcctccaa ccggatccca aagattacca
    10921 actactccac caacgtttgc aaaacgttga acattattta gatttccttc agcataacta
    10981 ttactaataa gcgcactatt ttctactgca ccaactattc caccaataga ctggtctcct
    11041 tgtgttgcat ttgaagataa atcgattgat gcgaacgact tatctattaa tcccctcgga
    11101 ccagaaagtt tgcctactaa acctccgatt tgataactag caactgtttt atatgtatta
    11161 gttattctac ctgtatagct actgttagaa atagtagaat tattaacttg tgatactaat
    11221 cctcctatgc tacgttcccc agctatcgct ccatcagcat gaacgttatc aatatgagta
    11281 ttgttatttg cttctttcgc aagtgttgca gtatcgtcct ttgcggaaat attaacatct
    11341 tttagtgaaa gtttttctac tgtagcacca tttaattccc caaataatgg ttttttcaaa
    11401 ttataaatag cataatattt ctcattattt gttcctacta atattccatg gaatacatta
    11461 ttcacataac tttcttgacc atctggaagt tcaacttcac gagcatccat agttgctcct
    11521 aaacggaatg tgccattagg attgctattc attgcatcta ctaaattttt aaatgatgta
    11581 tataccccag tttcactttg ctgagttttt ggtaaatagt atgtataatt ttctagtaca
    11641 ttattatttt catgttgtat cagactattt gcacttgcta ctatcttata aacatctcta
    11701 ttatctttag tatcattagt aatgcttgta actggtagca tcacatcttt aaagttctct
    11761 gatttaactt tcataaagta attttctgca ttacttggta aagaagcaag tgaagttaca
    11821 tgtcgatact tattaccatc ttttgaatat agttctacag aagatatatt tctaagttct
    11881 aatttcttaa taacttcttt ttcatcttta gcgtcatctt ttttctcatc tttatgacga
    11941 taaagttcat cgtatactgg tggaatttca ttacctgcta taatactctt aatccaagct
    12001 aattgtgtag gagataaaat caatccgcct gagcgatttt gtgctccatt ttgatgcaca
    12061 ccaataactt caccattagc attaaatatt cctccaccac tcataccagg atttccacct
    12121 tgatattgaa caccgtaggt gttattcgca tattcttgtt ccatttctac cgtagcatct
    12181 tttaagtgcg tatatttccc agctggatat ccatgaacat ttagtttgtc attaagattt
    12241 actttcgaat aatttttaac taattctaca tgttctctgc cagttgtttc aggtagctta
    12301 atcactgcta aatcatagat aaatcctttt ggataatctt ttttattata aaaatgaata
    12361 ttgttagcag taaatgttcc tttttgtcca tcaggagtca cccactcata tacgttttta
    12421 gatttatcac ctctaaattc gccagtagta ttatcagtag aattattaat gaaattatgt
    12481 gctactgtta aaagtacatt tggtgcaata aaagtagctg atcctactcc agtaaccttc
    12541 gacgaatctg taataaagtt catattaatt aatgcactag attttttctg aatactcatt
    12601 tcttctggtg tattagtatt ttcattattt ggtttagtat cttctgcact aggttgttcg
    12661 attttaccag tatattcttt cagtgcttct actttttctg gttctactat tgctccggct
    12721 tgcacccctg tgtattctgg tagtggtgct atctgctctg gttcaacaat agcgccagcc
    12781 tgcacccctg tgtattcttt tgatggttct actttttctg gttctactat tgctccggct
    12841 tgcactcctg tgtattcctt cggtgcttct accttctctg gttcgactat cgctccagcc
    12901 tgcactcctg tgtattcctt cggtgcttct actttctctg gctcgactat cgctccggct
    12961 tgcacccctg tgtattctgg tagtggtgct acctgctctg gttcaacaat agcgccagct
    13021 tgtactccag catattccgg ttcaactttt tcaggttcaa caatagctcc agcttgtact
    13081 cctgtatatt ctggtagcgg ttctacctgc tctggatcac ccttgtcagt catgactgcc
    13141 tctggtaacg ctggttgaac ttctggtacg cctttatcac ttactacagc ttctggcaac
    13201 tctggttgga ctgctgactc acctttgtcg gttaatacag ctgctggtag ttcaggctga
    13261 attgcgggtt caacaatagc tccagactgt acttccttat gttctgcacc agtctcagct
    13321 tgttccttta taacttgagc ttttttagta cctttttcga ctattcttga aacaggcgca
    13381 gtcgttgaag ttgaaataat ttctcgtgaa acttcttcat tgtttacaga aaatattctg
    13441 acgatttcaa ctttcttacc taatgcacct tcttgtttta ctcttacagt tccttctgct
    13501 aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtttctat agtttcgtca
    13561 cgatataaga gttccggttt gttcaactga cctgatagca cttcatcctg tggatttaat
    13621 gtatttaccc cagtcttttc ctttggagaa atcttctcct ctttcttcgt ttctagattc
    13681 ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt tcttggattg
    13741 attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt agttgaagaa
    13801 acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa atttggtgta
    13861 acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc ttgattactt
    13921 acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt gtaacctgaa
    13981 atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt attgtaattt
    14041 agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc cattcccgca
    14101 accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac agcaaaaatt
    14161 aaaattccca gagcagctaa gctagcacca gaaactaggg cttgcctctc attcttgctt
    14221 ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac aagataataa
    14281 gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt cttttcttct
    14341 gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc ttgagcatcc
    14401 acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc agatacaagt
    14461 cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata cttttccatt
    14521 attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat tagtgtatta
    14581 tctattatct atagaaaagg cagtatacct taattatact cttaatttac aaaaaagtct
    14641 taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca ataacaccta
    14701 ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa atggtttgag
    14761 gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat ggtcttcctg
    14821 caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt caaaggcttt
    14881 cattttatag aaaaagtcga tgagatgatc ggacaggtat tcagttgaaa agggtacttc
    14941 accacttttt cgatattcta ataagagcct agaaaatcga gctttttctt caggaagctc
    15001 acgaaaatag gaattgagga gccaagtctg cttctgtttt ctttcaattg gatcctgact
    15061 ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga tagcccgttc
    15121 tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag tcagggtctc
    15181 tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta gaaccagatt
    15241 gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg cctggatacg
    15301 gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga gttggtcatc
    15361 cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca tccgagcctt
    15421 tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga aaagctggta
    15481 gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt tttcccagag
    15541 ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt cttttttctg
    15601 agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt ccaattgctg
    15661 gtcaagggac aatcgatgaa aatgacgaac acagtcgcta ccaattggaa agaggcgttg
    15721 gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttccac agacacaatt
    15781 gctacggccg ataccgttaa aaatcaagga aacttcattc cattccttgg tagcttgttc
    15841 ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc taactggaag
    15901 tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta gaaagctagc
    15961 cgca
//
LOCUS       DAVBNZ010000050        15765 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000050 DAVBNZ010000000
VERSION     DAVBNZ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.050"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(1..261)
                     /locus_tag="VQ860_001647"
                     /pseudo
     CDS             complement(1..261)
                     /locus_tag="VQ860_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            386..844
                     /locus_tag="VQ860_001648"
     CDS             386..844
                     /locus_tag="VQ860_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET3120045.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            857..1465
                     /locus_tag="VQ860_001649"
     CDS             857..1465
                     /locus_tag="VQ860_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120046.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            1536..1868
                     /locus_tag="VQ860_001650"
     CDS             1536..1868
                     /locus_tag="VQ860_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120047.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            1879..3294
                     /gene="ply"
                     /locus_tag="VQ860_001651"
     CDS             1879..3294
                     /gene="ply"
                     /locus_tag="VQ860_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET3120048.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            4175..4891
                     /locus_tag="VQ860_001652"
     CDS             4175..4891
                     /locus_tag="VQ860_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3120049.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            5015..5484
                     /locus_tag="VQ860_001653"
                     /pseudo
     CDS             5015..5484
                     /locus_tag="VQ860_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5501..6322
                     /locus_tag="VQ860_001654"
                     /pseudo
     CDS             5501..6322
                     /locus_tag="VQ860_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            6329..7300
                     /locus_tag="VQ860_001655"
     CDS             6329..7300
                     /locus_tag="VQ860_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3120050.1"
                     /translation="MDFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPAQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSIGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQRVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMV"
     gene            7426..7788
                     /locus_tag="VQ860_001656"
     CDS             7426..7788
                     /locus_tag="VQ860_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HET3120051.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLTCLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            7785..8288
                     /locus_tag="VQ860_001657"
     CDS             7785..8288
                     /locus_tag="VQ860_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3120052.1"
                     /translation="MKNYQEWYRNIRSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            8402..8848
                     /locus_tag="VQ860_001658"
     CDS             8402..8848
                     /locus_tag="VQ860_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3120053.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKSPRLIF
                     YKGTGEYYLDLSEILFFETEGSKIYAHTQKNAYEVRLKLYELEAILPRYFSRVSKSTI
                     VNIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            8853..9527
                     /locus_tag="VQ860_001659"
     CDS             8853..9527
                     /locus_tag="VQ860_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120054.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYAK"
     gene            9688..9879
                     /locus_tag="VQ860_001660"
     CDS             9688..9879
                     /locus_tag="VQ860_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET3120055.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            10164..10463
                     /locus_tag="VQ860_001661"
     CDS             10164..10463
                     /locus_tag="VQ860_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET3120056.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            10460..10777
                     /locus_tag="VQ860_001662"
     CDS             10460..10777
                     /locus_tag="VQ860_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET3120057.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            10793..11419
                     /locus_tag="VQ860_001663"
     CDS             10793..11419
                     /locus_tag="VQ860_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET3120058.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            11452..12213
                     /locus_tag="VQ860_001664"
     CDS             11452..12213
                     /locus_tag="VQ860_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3120059.1"
                     /translation="MVKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            12291..12686
                     /locus_tag="VQ860_001665"
     CDS             12291..12686
                     /locus_tag="VQ860_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET3120060.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            12956..13240
                     /gene="groES"
                     /locus_tag="VQ860_001666"
     CDS             12956..13240
                     /gene="groES"
                     /locus_tag="VQ860_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET3120061.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            13256..14878
                     /gene="groL"
                     /locus_tag="VQ860_001667"
     CDS             13256..14878
                     /gene="groL"
                     /locus_tag="VQ860_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET3120062.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEVTGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            15016..15765
                     /locus_tag="VQ860_001668"
                     /pseudo
     CDS             15016..15765
                     /locus_tag="VQ860_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567576.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
BASE COUNT         4697 a         2874 c         3624 g         4570 t
ORIGIN      
        1 tccttagata gcgcatggtt atagacttta tcttcaactg ttagtggctt gagtttgctg
       61 gatttacgtg gagtttgtgc ttgaggatat atcttcatga gcccttgata attactgtca
      121 gccaagattt taccagcttg tccgactttt ttgataagct gtttttaata cagctaacat
      181 ctctttaaaa gtggtacgct gaacactaac aagacgctta aatcgtgcat cagttagttg
      241 tttacttgct tcataattca tagaactact ataccatatt ttgtttcgca ggaagtctaa
      301 taagttatag tccagttttt actatacttt gatattcaaa tatgttatac tatggttatc
      361 aaagtaaatg aaaggagtta cgaatatgac gccagaagaa atgtacctga cagagcgatt
      421 agacgtacag atagctcatt ttttaaagaa aagcgttcaa catcgtaggc gctataaggt
      481 attaaaaata acagaaatcg tggcaggttt cctcatagct gtcttttgtg ctattcctat
      541 gccaggtgat cgctaccgtt tgatttcggt tgccttatcc agtctcggct tgctgtgtga
      601 ggggattatc aatttgtata atgcaaagga aaattggatt tcttaccaaa aaactgcgca
      661 actcctggag aaagaaaaat tcctctatca atgccaaacg gagaaatatg caggaaagac
      721 caaggctttt gccctatttg tcaagacatg cgaaggtctt atctcagagg agattaacca
      781 gtgggaaagt atccagtcaa aagaagtggc agctagtgca gatgctccag ttaaaaaaga
      841 gtaggaggta gaggaaatgt ctcaatccag ttacctgtcg cccttgctct ggttaaaaaa
      901 agaagccgat aaggaaaaga tgagcgcgac ccagtgccag atatttttct tttactatca
      961 aatgtttgag ctcttatttg ctagagaaag cgacatgaaa gacttatgtc tgggaacgaa
     1021 aggtttttat ttctcgcagt tagagaaaaa tttgctttct ggagtttccc gatttctaaa
     1081 aaacttggag gggaaagtaa ctctcaaggc taaccaagaa gtatcagctc gcaaagccct
     1141 ttttctagcc ttgacaacta gccaatcaga ttggcaggag ttagctcctg tttttgattt
     1201 ttatcagact atcgggaggc ttgaaaatcc ttctctcttg agttctcagg acagacaaca
     1261 tctgatgtgg atttaccagt cagctttgga gaaggattat attgtcaagg ttattggcga
     1321 caagcatttt gtattgaaga gacaagatgc tactaaattg acagcgcgcc aaactcaaac
     1381 tttggaaatt ctgagtcaat cagaagactt ggtcaatcct gtctatgtta cattaggaga
     1441 aaagggggtg ctcttgcttg attaagagag gagatgttgt agctctttat ttgccttttc
     1501 cgactattag tagcgatttg gctgtgaaga atcatatgta tatctgtatt gacaacagca
     1561 tgactaaaaa caaagagttg gttaaaaatc agaccttcaa accagctctc ttgaccagac
     1621 gtttggtcaa gaactttatg atagaagagc cggatctagc tcgtaatcct tttacaagac
     1681 caaccttgat tgacttagat aaggtattta tgttggataa tacggttatt ccgacttctt
     1741 atctagccag acggcgacgc aatgtctcag aagaattgta cgaggaaatt ttggatcact
     1801 tagtccaacc acggctgatt tcgctgaaca agtctgagtt tatgcaactc aatccaggaa
     1861 cttattagga ggtagaagat ggcaaataaa gcagtaaatg actttatact agctatgaat
     1921 tacgataaaa agaaactctt gacccatcag ggagaaagta ttgaaaatcg tttcatcaaa
     1981 gagggtaatc agctacccga tgagtttgtt gttatcgaaa gaaagaagcg gagcttgtcg
     2041 acaaatacaa gtgatatttc tgtaacagct accaacgaca gtcgcctcta tcctggagca
     2101 cttctcgtag tggatgagac cttgttagag aataatccca ctcttcttgc ggtcgatcgt
     2161 gctccgatga cttatagtat tgatttgcct ggtttggcaa gtagcgatag ctttctccaa
     2221 gtggaagacc ccagcaattc aagtgttcgc ggagcggtaa acgatttgtt ggctaagtgg
     2281 catcaagatt atggtcaggt caataatgtc ccagctagaa tgcagtatga aaaaatcacg
     2341 gctcacagca tggaacaact caaggtcaag tttggttctg actttgaaaa gacagggaat
     2401 tctcttgata ttgattttaa ctctgtccat tcaggcgaaa agcagattca gattgttaat
     2461 tttaagcaga tttattatac agtcagcgta gatgctgtta aaaatccagg agatgtgttt
     2521 caagatactg taacggtaga ggatttaaaa cagagaggaa tttctgcaga gcgtcctttg
     2581 gtctatattt cgagtgttgc ttatgggcgc caagtctatc tcaagttgga aaccacgagt
     2641 aagagtgatg aagtagaggc tgcttttgaa gctttgataa aaggagtcaa ggtagctcct
     2701 cagacagagt ggaagcagat tttggacaat acagaagtga aggcggttat tttagggggc
     2761 gacccaagtt cgggtgcccg agttgtaaca ggcaaggtgg atatggtaga ggacttgatt
     2821 caagaaggca gtcgctttac agcagatcat ccaggcttgc cgatttccta tacaacttct
     2881 tttttacgtg acaatgtagt tgcgaccttt caaaatagta cagactatgt tgagactaag
     2941 gttacagctt acagaaacgg agatttactg ctggatcata gtggtgccta tgttgcccaa
     3001 tattatatta cttgggatga attatcctat gatcatcaag gtaaggaagt cttgactcct
     3061 aaggcttggg acagaaatgg gcaggatttg acggctcact ttaccactag tattccttta
     3121 aaagggaatg ttcgtaatct ctctgtcaaa attagagagt gtaccgggct tgcctgggaa
     3181 tggtggcgta cggtttatga aaaaaccgat ttgccactag tgcgtaagcg gacgatttct
     3241 atttggggaa caactctcta tcctcaggta gaagataagg tagaaaatga ctagtagagg
     3301 agaatgcttg cgacaaaaag aggcgatgat ctctctgcgg atatctgaaa gtttatctct
     3361 tgcctagcga tttccattgg agtatgctcg tgatgttaaa atgaatctat caaacagaat
     3421 gtgtaaaaaa gtaaaaaggg tagccaattc cttgatatac aggggattga ttatccttta
     3481 cttgttttag atgattggaa attcaagaat gacacgtatc ggaaatattt tgctgtttat
     3541 atctaatacc catttatgga aaaaatgaaa ttaaatatga acaaatcaat tgctagcaat
     3601 ggtttagaag tgccagtgta ctagtctaat ttctccatct tgggaacacg taaattatac
     3661 tcttcgaaaa tctcttcaaa ccaggtcagc cctatccgca acctcaaaac agtgttttga
     3721 gcaacctgcg gctagctttc tagtttgctt tttgattttt attgagtatt agaggtttgc
     3781 ttagaaactc ttctattgat ttcttagaat acaatagcgc ctataagaac tgttggattt
     3841 caaagtattt acttgaacta tgatatgtct ggagtagact gtcaacaaaa ggtgcagtat
     3901 gattgttttt gtcgcttata tctacaaact tcaaacagta atttgagctg actttgtcaa
     3961 acttggctga aactttctat ttgcagataa tggtctagtt tgttttttga atgtggatga
     4021 gtgtctgttg ataaagatag aaaggtaaga ccatcttagc aggtaaagtg ctatcctagc
     4081 ttgatttgct aataaaatcc atttcctcta gtgaaaatca aaaaaacttg tgttataata
     4141 agaaagatta aaatgtgaaa aaaggagatt cctaatggga cgtaaatggg ccaatatcgt
     4201 agccaagaaa acggctaaag atggagctaa ctctaaagta tatgcaaaat ttggtgtaga
     4261 aatctatgta gcagctaaaa aaggtgatcc agatccagaa tcaaactcag ctttgaaatt
     4321 cgttatcgac cgtgctaaac aagcccaagt gccaaaacac attatcgata aagcgattga
     4381 taaagccaaa ggaaacacag acgaaacctt tacagaagga cgttacgaag gttttgggcc
     4441 aaatggctct atgctaattg tggatacttt gacttctaac gttaaccgta cagcagccaa
     4501 tgtccgtgca gcctttggta aaaacggcgg aaacatgggc gcttcaggtt ctgtttctta
     4561 cctttttgac aacaaaggtg ttattgtatt tggaggtgaa gatgcggacg cagtctttga
     4621 gcaattgctc gaagcggatg tggatgtgga tgacgtagaa gcacaagaag gtacaatcac
     4681 agtttacaca gcgccaactg accttcacaa ggctatcgtt gctctccgtg agtctggtat
     4741 tgaagaattc caagtgactg aattggaaat gattcctcag tcagaagtgg aattgtcagg
     4801 cgaagacctt gaaacctttg aaaaacttta cagcgttctt gaagacgacg aagacgtcca
     4861 aaagatttat acgaacgtag atgggtttta atttaaccta tagaacatga tcctaagtga
     4921 gaaaatcact tgggattttt ttaatcaaga aaatagttct catagaaatt taattattct
     4981 ccagagaact atttttattt agaaggggga gattatggat aaaccgatgt tagtctttaa
     5041 gcgttttggt catcaaattt acctgatggt gcaaaaggaa gccaaacgtt gcggcattga
     5101 atttatgggt gggccgcaag gtcaggttgt gcgttttttg gataatcgcg agaaaaacca
     5161 agacttggtc ttgattaaag atatcgagca ggaactcaat attaccaagt ctgttgctag
     5221 taatctggtt aagcgtatag tgcaaaatgg tttggtggaa ttggaggcga gtcctgttga
     5281 taagcgggct aagtttgttc gtctgacgga caaagcacgt tctcagatgc aacaggttaa
     5341 ggcttttttg aacgcataga caagcagttg atggaagaca ttgatgaaga tgaattactg
     5401 atttttgaga aagttctcgg tcaactacag gcaaatatca agggaatagg aggagagaat
     5461 aaagaaatta gccaaaagaa ttagtagaaa agaatggggg atgattttac tagccattct
     5521 ctttacttgc ttttcggtct atctagagtt ggaagtgccg acctatatct cgaaaattac
     5581 ggatttgcta ggtagtcaag gaactaattt agatgagttg tggcagccgg caagcatgat
     5641 gatgggaatg ccctttcttg ccttcttgtc cgtagttgca gttggatttt ttgcatcccg
     5701 agtggcggct tcttatacta gtaggctgag aagtgatatt tttaaccgag ttttggatta
     5761 ctcgcagaca gagattaaga aattttcaat tcctagcctc ttgatgcgta ctaccaatga
     5821 cattactcaa gttcaaatgt tgattactat ggacttgcaa gtggtaacgt gtggtccaat
     5881 tatggctatc tgggctattg ggaagatttt aggtcattca gaatactggc tctgggccgt
     5941 acttgtggca gtgattgtca acgtcctgat gacgaccgtt ttgatgacgc tagcctttcc
     6001 aaaacagtcc ttgattcagg ggctgacaga taaactgaac agtatcactc gtgagagttt
     6061 aacaggtatt cgtgtcgttc gtgcctacaa tgcagaggat tatcaaaatg aaaaatttgc
     6121 agcagtaaat gatgaattga cccgttaaaa tttgtttgtc aaccgtctta tggctatttt
     6181 gaatcctatc atgatgggga tttcaagtgg tttgagtgtg gcgatttact ggattggggc
     6241 ctatgtgatt aacgacgctg ctccgatagc gcgtctgcct ttctttagtg acatgattgt
     6301 tttcatgtct tatgccatgt aggttgtcat ggacttcctt ctcatgggag cactcttcat
     6361 cgttcttccc cgaactatgg tctctgctaa gcggattaat caagttttag atttgcattc
     6421 ttctatccaa aaccctgctc aagtgcagct gactgatgaa aacttcaaag gtcaggtcga
     6481 gtttaaggat gtgaccttcc gctatgcggc aaattcggag gcagttattg aacatgttag
     6541 ctttaaagca gaaactggtc aaacagtggc ctttattggg tcaataggtt ctggtaaatc
     6601 aactctggtc aatctgattc cacgtttcta cgacgtgtca gcaggagaaa ttctggtgga
     6661 cggtgtcaat gttcaagact atgacttctc tgcgacagct catgctggtc aaagggttgc
     6721 cattgttggg ccgactgggg ctggtaagac aaccattgtc aatcttttga tgaaattcta
     6781 tgagattgat aagggaagta ttcgcattga tggtgtggat accaaggcta tgacgcgttc
     6841 agaagtgcat gatgcctttt caatggtctt gcaggatacc tggctctttg aaggaactat
     6901 tcgagacaat ctcatctata atcaaatagg gattagtgat gaacgaatga tggaagctag
     6961 taaggctgtg ggaattcacc actttattat gaccttgcca gatggctatg ataccatctt
     7021 ggatgacacc gtgaccttgt ctgtaggaca aaaacaacta ttgactattg ctcgtgccct
     7081 tcttaaggat gcaccgcttt tgattttgga tgaggcgact tcttctgttg acacacggac
     7141 agaggaattg atccaaaaag ccatggaccg tttgatggaa ggacgcacat cctttgtcat
     7201 tgcccaccgc ttgtcaacca tccgaaatgc agacttgatc ttggtcatga aagatggaaa
     7261 tatcatcgag caaggcaact atgaggaact gatggtgtaa ggtggcttct acgctgactt
     7321 gtacaatagt caatttacag aagatgaagc agaagaataa atcaaaagaa ggcttgacgg
     7381 ccttcttttt cttatttata ctagtacaca tagaaagaga gaagtatgag tcagaaatta
     7441 tacaatatga aatttgctgc tgtctactta gccttgattg caaaagttga gcgaaagggt
     7501 ggaaaggcag agtcagttca ccaagtgacc agttggttga cagggtatga agtgagtgac
     7561 gttcttactt gtctggatag ggatgttact tacggagatt tttttcgaca agcaccatat
     7621 tatgtccctg aacgaattgc aattacaggg aagatttgcg gtgtccgtat tgaggaaatt
     7681 gatgatcctc tgatgcagga aatacgtcgc ttggacaagc tagtggattg gcttgccaag
     7741 gggaaaacat ctcaacaagt tctagaaaag tatgagaagc ataaatgaaa aattatcaag
     7801 aatggtatcg aaatatcaga tccagactaa ctagtcgtcc aattctttta ttcctattac
     7861 gcagtttcaa tcgtttgatg acagtcgcca tgcccctggt ctatctgatc ttgctagtca
     7921 ccacttacct gcaactagga cttggtcagc aagttggagt ttatgtgctt attcctgcat
     7981 caggttttgt ggccttgtcc ctgtttcgta aaaaaatcaa tcacccgaga ccttatgaaa
     8041 cttgggatat ctgtcccctt cttgataagg atagttcggg acggtcgatg cccagtcgcc
     8101 atgtcttttc tgcaactatc atctccatgg cctgtctgca tgctagtcta cctattggct
     8161 tagtatgctt gatcttttca gctttgctgg ggttggtgag ggttttaggg ggtgttcatt
     8221 atcccaagga tgtcttggtt ggctatgctt gtggtctggt gtggggattc cttttcttct
     8281 tattctgaca tgtaagttaa gctagtccta caaccactta ctgcttcaaa ttgaccactt
     8341 gcttttttgc ccttgtattc ctaacttagc tttgatatag tagagtcaga aaggagatgt
     8401 gatgaagtta cgaattgaga ttgacggcaa tttagaggag actgaaattg tcatcaagac
     8461 ccccactttg acagatgaaa ttgcagactt gcaacggctc ttgcaagaat ccaagtctcc
     8521 taggttgatt ttttacaagg ggacgggtga atattatctg gacttgtcgg aaattctctt
     8581 ctttgagaca gaaggtagca agatttatgc ccatacccag aaaaatgcct acgaagttcg
     8641 gctcaaactc tatgagttag aggctatcct tcctcgctat tttagtcgag tatccaagtc
     8701 aacgatcgtt aatattcggc aaatctattc ggtggacaag tccttttcag gaacgggcac
     8761 catttccttt tatcaaaccc acaaggaggt tcatgtgtca cggcattacc aatccctcct
     8821 aaaagaaaat ctaagaaata tgaggtaaga acatgaaaaa gaaagcattt ggtattgtgt
     8881 tgcttgtact agcagcttta atattagtac aaggaaattt tggaatccct tctctaggag
     8941 ggcacatttg gcccttgatt ggtattgctt tttttgccta ccaatcagtt ggagctttgt
     9001 tgcgtcgcca cttaacttca gcctctttta cagctctagt agccttaatg attgctaacc
     9061 acttttatgg cattttaccg attccaaacc agacactaat ctgggcagga gttctaatcg
     9121 ttctcggagt aaatatgttg actcattcta acagaacttg gaatgggaaa aaatggtggt
     9181 atgatggtga aaaaaacatt cttatagata aggaagttgc ttttgggaca gggactttct
     9241 acaagcaaga ccaagaattg gtagaagacc aagtagaagt tggttttggc aatgcaaaaa
     9301 tctactatga caatgcagag atgttaggtg attttgcaac tttaaatatt gaagtagctt
     9361 ttggtaatgc aactgtctat gttccgcaac actggcgtgt cgatttgaaa gtagaaacat
     9421 cctttggtgc agccaaggcg gacgctcctg tagccccaac cagcaaaacc ttgattatcc
     9481 gtggagatgt ggcttttggg aagttggaaa ttgtctacgc taaataaaaa aatcttcact
     9541 tcaaccatca aaataggcgt actaagagta ggaaattgat gccttgctct gatttcagtt
     9601 ctatggttgt tagactttaa aaaatgaaat gctgccttta aaagttgtat atttttcgat
     9661 attttggctt ttacgtttga tgtatctatg tactacagcg tagatgatgt agtgtcgaat
     9721 gcttttaaaa aacgaatgat attggacagt ttttttgcct ttaattgctc aggaaccatg
     9781 aaagtcagta cttgggttta tgacaaggga gaatggtatt atgtaagttc ttctggttcc
     9841 atgattgcga atgattgggt caaagacaat ggcaagtagt attatctggc ttcatcaggt
     9901 aagatgcttc gcaataccta cacacctgat ggttactacg ttggcaactt aggtgcctgg
     9961 caataagaat aatactcttt gaaaatctct tcaaaccacg tcaacgtcgc cttatctaca
    10021 acctcaaaac cgtgttttga gcagcctgcg gctagctttc tagtttgctc ttagtataag
    10081 aagtcctttt ccttaaagga agaggctttt tacttgcttt tctgctgctt cctcatttgt
    10141 cctgaagcct tttttgtgtt aaaatgaatg gtatgaaagc taaaaaaatg tggatggcag
    10201 gcttggctct gctaggtatc ggaagccttg ctcttgctac gaaaaaagtt gcagatgacc
    10261 gtaagctcat gaagactcag gaagagttga cagagattgt gcgagaccat ttttccgaca
    10321 tgggggaaat tgcgaccctt tatgttcaag tttacgaaag cagtctggag agcttggttg
    10381 gtggcgtcat ttttgaggat ggccgtcatt atacctttgt ctatgaaaat gaagacctag
    10441 tctatgagga ggaagtctta tgatacagcc agcaagttta gaagaattag catctttagt
    10501 ggaaaaagcg ggcaagaagg tcttcctttt tgtggcagac tggtgtggcg attgtcgtta
    10561 tatttatcct gccttaccag agattgaaga gaccaatcca gagttcacct ttattcgaat
    10621 ggaccgagat cagtatatgg atttggccaa actctgggat gtttacggaa ttcctagcct
    10681 tgttgttcta gaaaaggaca aggaaatcgg tcgttttgtc aatcgcgacc gtaaaagtaa
    10741 ggagcaaatt aacgattttt tagcaggatt gaaataggag aaaaaggaaa caatgatttt
    10801 tacgtataac aaagaacatg tcagtgatgt ccttatggtc atcgtgaaaa atagcggaga
    10861 tgccaaactg aatgtggaac gcaaaggcaa ggtagcccgt gttttcctca aagaaaatgg
    10921 ggaaacagta gcttggaaca tttttgaggt ttcgagcttg tttgaaattg cagagcgcgg
    10981 tcaagtcttt ttatcagatg agcaagtcgc tcgtttgaac caagaattac aggcggaagg
    11041 ttttacagaa gaaattgtta atgataagga acctaagttt gttgttggtg aaattgtcga
    11101 gatggtagct catccagaca gtgaccacct caacatctgc caagttgcag tcgcaagtga
    11161 caagatagtg caaatcgttg caggagcacc taatgcgcgt gttgggttga aaaccattgt
    11221 ggctcttcct ggtgccatga tgccaaaagg gaatttcatt ttcccaggcg aacttcgtgg
    11281 tgaaaagagt tttgggatga tgtgtagtcc tcgtgaattg catttgccaa atgctccgca
    11341 aaaacgtggg gtgcttgaat tatcagaaga ccaagttgtc ggaacaccgt tcgacccagc
    11401 gaaacactgg actgcctagg aacttgtcag catctgatag aaggaaataa gatggtaaaa
    11461 aatgtagtga ttacgggagc aacctcagga atcggtgaag cgattgcgcg tgcttatctg
    11521 gagcagggtg aggatgtcgt tctaacagga cgacggatag acagattaga aatcctcaag
    11581 tcggagtttg cagtaagctt tccaaatcaa accgtctgga cttttccact agatgtgacg
    11641 gatatggtca tggtgaagac tgtttgctct gatattctag aaacgatagg gaggattgat
    11701 atcttggtca acaacgccgg actggctctt gacttggctc cctatcaaga ctatgaggag
    11761 ttggatatgt tgaccatgtt ggataccaat gttaaaggtc tgatggcggt tactcgctgt
    11821 ttcttgccag caatgataaa agtcaatcaa ggtcatatta tcaatatggg gtcaaccgca
    11881 ggaatctacg cctatgctgg tgccgctgtt tactcagcta ccaaggctgc ggttaagacc
    11941 ttttcggatg gactgcgaat tgataccatc gcaacggata tcaaggtgac aaccattcag
    12001 cctgggattg tcgaaacaga tttctcaact gttcgttttc atggtgataa agagcgagct
    12061 gcgtccgttt accaaggaat agaagccttg caagctcagg atattgcaga cacagtagtc
    12121 tatgtgacca gtcagcctcg ccgtgttcag attacagata tgaccattat ggccaatcaa
    12181 caggcgacag gtttcatgat tcataaaaaa taagaaattt cctcgaaaag ttacaaattt
    12241 ctgtaacttt ttttgatttc ctacgaatag ataagtagga ggaagaaaat atgtataata
    12301 aagttatcat gattgggcgt ttaacgtcta caccagaatt gcacaaaacc aacaatgaca
    12361 agtcggtagc gcgagcaact atcgctgtga accgtcgtta caaagaccaa aacggtgaac
    12421 gtgaagctga ttttgtcaat atggtcctat ggggcagact agcagaaact ttggcaagct
    12481 acgcaaccaa aggtagtctc atttccgttg atggagaatt gcgtacccgt cgctttgaga
    12541 aaaatggcca aatgaactac gtgaccgaag tacttgtaac aggattccaa ctcttggaaa
    12601 gtcgtgctca acgtgccatg cgtgaaaata atgcaggcca agatttggca gatttagtct
    12661 tggaagagga agaattgcca ttttaatact cttcgaaaat ctcttcaaac cacgttagct
    12721 ttatccacaa catcaaagca atgctttgag cagcctgcgg ctagcttcct agtttgctct
    12781 ttgattttca ttgagtataa acattaaaaa gtctgagttg gtctcaggct ttttatcttg
    12841 agaaagtcag acttttttct tgattatttc tgactaagtg atacaataga actatgaatt
    12901 agcactcagg tataaagagt gctaataata tctatctcat tatggaggaa atcagatgtt
    12961 gaaaccatta ggggaccgtg tggtcttaaa aatagaagaa aaagaacaaa ccgttggggg
    13021 ctttgttctc gcaggttcag cccaagaaaa aaccaaaaca gcccaagttg tggctactgg
    13081 acaaggtgtt cgtaccttga acggtgactt ggttgctcca agtgttaaaa ctggagaccg
    13141 tgtcttagtt gaagcccacg caggtcttga tgtcaaagat ggcgatgaaa agtacatcat
    13201 cgtaggcgaa gctaacatct tggcaatcat tgaagaatag aaggagaaag taagtatgtc
    13261 aaaagaaatt aaattttcat cagatgcccg ttcagctatg gtccgtggtg tcgatatcct
    13321 tgcagacact gttaaagtaa ccttgggacc aaaaggtcgc aatgtcgttc ttgaaaaatc
    13381 atttggctca ccattgatta ccaatgacgg tgtgactatt gccaaagaaa tcgaattgga
    13441 agaccatttt gaaaatatgg gtgctaagtt agtatcagaa gtagcttcta aaaccaatga
    13501 tatcgcaggt gacggaacta cgactgcaac agtcttgacc caagctatcg tccgtgaagg
    13561 aatcaaaaac gtcacagcag gtgcaaatcc aatcggtatt cgtcgtggga ttgaaacagc
    13621 agttgccgca gcagttgaag ctttgaaaaa caacgccatc cctgttgcca ataaagaagc
    13681 tatcgctcaa gttgcagccg tatcttctcg ttctgaaaaa gttggtgagt acatctctga
    13741 agcaatggaa aaagttggca aagacggtgt catcaccatc gaagagtcac gtggtatgga
    13801 aacagagctt gaagtcgtag aaggaatgca gtttgaccgt ggttaccttt cacagtacat
    13861 ggtgacagat agcgaaaaaa tggtggctga ccttgaaaat ccgtacattt tgattacaga
    13921 caagaaaatt tccaatatcc aagaaatctt gccacttttg gaaagcattc tccaaagcaa
    13981 tcgtccactc ttgattattg cggatgatgt ggatggtgag gctcttccaa ctcttgtttt
    14041 gaacaagatt cgtggaacct tcaacgtagt agcagtcaag gcacctggtt ttggtgaccg
    14101 tcgcaaagcc atgcttgaag atatcgccat cttaacaggc ggaacagtta tcacagaaga
    14161 ccttggtctt gagttgaaag atgcgacaat tgaagctctt ggtcaagcag cgagagtgac
    14221 cgtggacaaa gatagcacgg ttattgtaga aggtgcagga aatcctgaag cgatttctca
    14281 ccgtgttgcg gttatcaagt ctcaaatcga aactacaact tctgaatttg accgtgaaaa
    14341 attgcaagaa cgcttggcca aattgtcagg tggtgtagcg gttattaagg tcggagccgc
    14401 aactgaaact gagttgaaag aaatgaaact ccgcattgaa gatgccctca acgctactcg
    14461 tgcagctgtt gaagaaggta ttgttgcagg tggtggaaca gctcttgcca atgtgattcc
    14521 agctgttgct accttggaat tgacaggaga tgaagtaaca ggacgtaata ttgttctccg
    14581 tgctttggaa gaacctgttc gtcaaattgc tcacaatgca ggatttgaag gatctatcgt
    14641 tatcgatcgt ttgaaaaatg ctgagcttgg tataggattc aacgcagcaa ctggcgagtg
    14701 ggttaacatg attgatcaag gtatcattga tccagttaaa gtgagtcgtt cagccctaca
    14761 aaatgcagca tctgtagcca gcttgatttt gacaacagaa gcagtcgtag ccaataaacc
    14821 agaaccagta gccccagctc cagcaatgga tccaagcatg atgggcggga tgatgtaagc
    14881 attctataga aaacaactta taaaaaacac aaaaggaggg aatgactaac ccttcttttt
    14941 ataatattca cttctaaatt gatttgagct ctcctaactt atatgataaa ataagactag
    15001 aaaaaggaga agaacatgat cgatgtagaa aaaattctgt gcaagatgcc ccccaatcag
    15061 aagattaatt atgaccgtgt catgcagaaa atggtagaag tatggtagaa aaatgagcaa
    15121 cggccaacca ttctcgtgca tgtttgctgt gccccttgta gtacctatac actagaatat
    15181 ttgaccaagt atgcagatgt gaccatctat tttgccaatt ctaatatcca tcccaaggta
    15241 gaataccata agcgggtcta tgtcaccaag aaatttgtta gtgattttaa tgagcggaca
    15301 ggaaatacgg ttcagtacct agaagctccc tacgaaccca attaataccg aaaactagtt
    15361 aggggactag aggaggagcc cgaaggtggc gaccgttgca aggtttgttt tgactaccga
    15421 ctggataaaa cagcgcaagt ggctatggac ttgggctttg actactttgg ttcagccttg
    15481 accatcagtc ctcataagaa ttctcaaacc atcaacagca tcggaatcga tgtgcaaaaa
    15541 atttacacga cccactatct tcccaacgat ttcaagaaaa atcaaggcta caaacgttca
    15601 gtagagatgt gtgaggagta tgatatctat cgtcaatgtt attgtggctg cgtctatgca
    15661 gcccaagccc agaatattga cctggttcaa gttaagaagg acgctacagc attcttgttg
    15721 ggtaaggatg ttgagaaaga ctattctcat atcaaattta tagta
//
LOCUS       DAVBNZ010000051        14761 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000051 DAVBNZ010000000
VERSION     DAVBNZ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.051"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            83..880
                     /locus_tag="VQ860_001669"
     CDS             83..880
                     /locus_tag="VQ860_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET3120063.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGFLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="VQ860_001670"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="VQ860_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2383..3657
                     /locus_tag="VQ860_001671"
     CDS             2383..3657
                     /locus_tag="VQ860_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET3120064.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VQ860_001672"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VQ860_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET3120065.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMAEFMQDEGKIYEGEITLGYSTTTEDTSGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VQ860_001673"
     CDS             4786..5088
                     /locus_tag="VQ860_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3120066.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VQ860_001674"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VQ860_001674"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET3120067.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VQ860_001675"
     CDS             5962..7302
                     /locus_tag="VQ860_001675"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET3120068.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VQ860_001676"
     CDS             7280..7492
                     /locus_tag="VQ860_001676"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET3120069.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VQ860_001677"
     CDS             7489..8364
                     /locus_tag="VQ860_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET3120070.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VQ860_001678"
     CDS             8357..9172
                     /locus_tag="VQ860_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET3120071.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VQ860_001679"
     CDS             9165..9596
                     /locus_tag="VQ860_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3120072.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VQ860_001680"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VQ860_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET3120073.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VQ860_001681"
     CDS             11272..12000
                     /locus_tag="VQ860_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET3120074.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VQ860_001682"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VQ860_001682"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET3120075.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14106..14186)
                     /locus_tag="VQ860_001683"
                     /pseudo
     CDS             complement(14106..14186)
                     /locus_tag="VQ860_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14360..>14761
                     /locus_tag="VQ860_001684"
     CDS             14360..>14761
                     /locus_tag="VQ860_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3120076.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGN"
BASE COUNT         4396 a         2672 c         3483 g         4210 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ttcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagttatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt tgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gcattggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggccatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttag ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggccttattg gctaaggaca aggaagtaca ggccttggaa
     2701 aaccagttgg cgaccttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa tgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggccgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatacta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgct aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccagaatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaaacggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgca ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtttatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgaaacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggtaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gtaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattggaag aaattgccca gcaggttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta aggttcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggta ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattgccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctca
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgaa atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccat ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggag
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccatttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aaatacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgcc ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aatcatgttt tgagctgact
    14101 tcgtcagttt catctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    14221 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaaa gagacaaaaa
    14281 agaatagaaa gtaattaaca acgatttcat atagtgttat acttatagca taaagttaat
    14341 ggaaagaagg gaaaacctta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg
    14401 cttagaagcg gataatcaag aacaactctt tgatcaggta gcaagcttgt tggaagaacg
    14461 agaaattgtc actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac
    14521 tggtttagat atggaatttc taggaaagga cttgccaaat gtagcgattc ctcacacaga
    14581 tattgttcat aatctagctg aaaaagtggt ggttgttcga ttagaaaaac cagtaacttt
    14641 tcacaatatg attgcgccag gtaaggaagt agaagtatcc ctactcttct ttatcattaa
    14701 caattcaagt tcaagtcaaa caaatattct ggctcagttg atggactttt tcacaggaaa
    14761 t
//
LOCUS       DAVBNZ010000052        14344 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000052 DAVBNZ010000000
VERSION     DAVBNZ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.052"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(83..646)
                     /locus_tag="VQ860_001685"
     CDS             complement(83..646)
                     /locus_tag="VQ860_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3120077.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(630..1181)
                     /gene="coaC"
                     /locus_tag="VQ860_001686"
     CDS             complement(630..1181)
                     /gene="coaC"
                     /locus_tag="VQ860_001686"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET3120078.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="VQ860_001687"
     CDS             complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="VQ860_001687"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET3120079.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2112..3782
                     /locus_tag="VQ860_001688"
     CDS             2112..3782
                     /locus_tag="VQ860_001688"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET3120080.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            4110..5285
                     /gene="mutY"
                     /locus_tag="VQ860_001689"
     CDS             4110..5285
                     /gene="mutY"
                     /locus_tag="VQ860_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET3120081.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            5341..6045
                     /locus_tag="VQ860_001690"
     CDS             5341..6045
                     /locus_tag="VQ860_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3120082.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            6038..7387
                     /gene="vicK"
                     /locus_tag="VQ860_001691"
     CDS             6038..7387
                     /gene="vicK"
                     /locus_tag="VQ860_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET3120083.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            7389..8198
                     /locus_tag="VQ860_001692"
     CDS             7389..8198
                     /locus_tag="VQ860_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3120084.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKNKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            8289..8531
                     /locus_tag="VQ860_001693"
     CDS             8289..8531
                     /locus_tag="VQ860_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET3120085.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVANLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            8533..8787
                     /locus_tag="VQ860_001694"
     CDS             8533..8787
                     /locus_tag="VQ860_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3120086.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            8834..9577
                     /locus_tag="VQ860_001695"
     CDS             8834..9577
                     /locus_tag="VQ860_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET3120087.1"
                     /translation="MKKKCFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLIGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDVVPTSIFGKWLAVLLMLVGIGTIGMLTSTLTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELH"
     gene            complement(9867..10853)
                     /locus_tag="VQ860_001696"
     CDS             complement(9867..10853)
                     /locus_tag="VQ860_001696"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET3120088.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            11047..13515
                     /gene="gyrA"
                     /locus_tag="VQ860_001697"
     CDS             11047..13515
                     /gene="gyrA"
                     /locus_tag="VQ860_001697"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET3120089.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            13515..14258
                     /gene="srtA"
                     /locus_tag="VQ860_001698"
     CDS             13515..14258
                     /gene="srtA"
                     /locus_tag="VQ860_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET3120090.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         4393 a         2477 c         3188 g         4286 t
ORIGIN      
        1 ttttactata gtaaagattt cattaaaaag aaactgtata gagcaaaatc tccaccttca
       61 ggtttgaaag cggagattgt ttttattttt tcaaggtttg tagtcgtgga acaatggcta
      121 gggttagaat tgcagaaatg accaattcag caattgaatt tgttgagata acggttgcca
      181 gaagaagttg gatatttcca ttataaacat ttccaaatag gaagaagatt cctccaagga
      241 caaagatagt atttgtcaag gaaccaagag ccccagctaa aatcagacca gtcttgtttt
      301 tcatcagttt atagactaag taaggagtta aaccaatcaa aatacgtggg acaatggcaa
      361 tgatagctga gtagatgttt ccgtttggta cgaagggaga gaagaggtag cttgtcggta
      421 gaatcgtaat cgtgttaacc gtcaagctaa gtaatcccat caaaaatcca agtgtaaccc
      481 caactcgtgg accataaata atgctggcaa taatgacagg aatatgaaca atggtcggtt
      541 tgattggaaa tggaaaaagg ttaaagataa gtgagctcag aaagtgtatc acgagcatgg
      601 tagcaaaaaa gatagcaatg ggtgcaatat tagagcgttt tttcatcgag agtttccttt
      661 attctttcta aaataattgt gaggtcagct aaagctcctc gtccgtggtc tccacaagct
      721 agtagggatt ccttaggagc aatcagctga tagccgtagg tttctaatgt tttcagatta
      781 ttctgagtta ctggatggtc atacattttt gtattcatag caggagctat tagtttggga
      841 atatgacttg gtagggctag agctgtactg gttaccatgt tgtccgcaaa tccgtgagct
      901 agttttgcaa tagtgttagc agttgcaggt accacgataa ataaatctgc tttttttcca
      961 agttcgatat gattgacctg atcaggatag ggttccttca tgacatccaa gtggacagga
     1021 ttctgtgaga gtacctgtag tgtcaaaggt tggataaact ctgtagcagc ctgagtcatt
     1081 aagacagtga cttgatggcc ttgttttttt agagaactga ctaaatctgc cgacttataa
     1141 gaggcgattg aacccgttac agccaagaga atgtttgcca tagttttcct ttctaagaat
     1201 gataggcttg aattttttca aggaggagtt ctgcaatttc ttctttagtc tggactgttt
     1261 gaagctgatt tttctcaaca aatatagctc ggtgctgatc tgctgaaatt tgagtcaggt
     1321 cattcgcgat gattaaatct gcttgattct tgataagact ttttcgtgca atgtcaacca
     1381 gatgatcttc ggtaacatca accagcagtt tgaaaccaat cagatgaata gtaggattcc
     1441 attccttgac tagggatatg attttgggtg tctttttaag gaacaaaacc tgaacctcat
     1501 cagttgaaga aatcttggcc tgatgattct gcttgcttaa aaattctttt agattggagc
     1561 tagcctgaac ttcctcaagc cctgtcatat aaacaggagt gtagtcagaa acagccattg
     1621 agtggatcaa gacctgataa tcctgaacac gttcttgcat ttctattaga aggtccttgg
     1681 tattggtaat ttctcgaata cttaggttag gatgaggctc tggcttcaga gctcgttttg
     1741 tcgtaattaa acaaacttca tgccctgcag aaagcaaagt ctctgtgata attttcccca
     1801 agtgacctgt agaatggtta gtgatagagc ggacgctatc gatagcttca ctggtaccgc
     1861 ccgatgtaac taaaattttc atagcactat tgtacacaaa aataagcggt aagtaaaatg
     1921 aaagtgataa atttttggta aaaacgaaga tttattatag tttcaaacta taaagccata
     1981 taaaatttaa gaaaggactc taaaagtctt aaaaacagag atatttacga acgtttagag
     2041 agttttagga tgttaaaaat cttgttttgt gatataatga attatcatat aagaggttag
     2101 aggaattttg aatgaaaaca gatattgaaa tcgcacagag tattgagttg aagccaattg
     2161 ttgatgttgt agagaaactt ggtatttctt atgacgattt ggagttgtac ggaaagtaca
     2221 aggctaaact cagctttgat aaaattcgtg cagttgagag caatccagtc ggtaaattga
     2281 tcttggttac tgccatcaac ccaacacctg caggtgaagg aaagtcgacg cttaccattg
     2341 gtcttgcgga tgccttgaac aagattggca agaaaaccat gattgctatc cgcgaaccgt
     2401 ctcttggtcc agtcatgggg atcaagggtg gtgctgctgg tggtgggtat gcacaagttc
     2461 tgccaatgga agacatcaac ctccacttta ctggagatat gcatgctatt acaactgcca
     2521 acaatgccct ttctgccttg attgacaacc acttgcacca agggaatgag ctgggaattg
     2581 atcaacgtcg tatcctctgg aaacgcgttg tggacttgaa cgaccgtgcg ctccgccatg
     2641 tgactgttgg tcttggtggt cctctaaacg gtattccacg tgaggacggt tttgatatta
     2701 cagttgcttc agaaatcatg gcaattcttt gcttggcaac ggacatcgag gacttgaaac
     2761 gtcgtttggc gaatatcgtt attggttatc gctatgaccg tacgcctgtt tctgtaggtg
     2821 atttgcaggt tgagggtgcc ttggctttga ttttgaagga tgctattaag ccaaacttgg
     2881 ttcagacaat ttacggtaca cctgcctttg tacacggtgg tccatttgcc aatatcgctc
     2941 atggctgtaa ctctgttttg gcgacgacaa cagcccttca cttggctgat tacactgtta
     3001 ctgaagctgg ttttggtgcg gatcttggtg ctgagaaatt ccttgatatc aagacaccaa
     3061 acttgccaac atctccagat gcagttgtta ttgtcgcaac ccttcgtgcc cttaagatga
     3121 atggtggtgt ggctaaagac gctctgactg aagaaaatgt agaggcagtt cgtgcaggtt
     3181 ttgctaactt gaaacgccac gttgaaaata tccgtaagtt cggtattcca gcagttgtag
     3241 ctattaacga atttgtatct gatacagaag ctgaaattgc agtcttaaaa gaactctgtg
     3301 cctcaatcga tgtaccagtt gaattggcta gtgtctgggc tgatggagca gaaggtggag
     3361 tagcacttgc cgaaacagtt gttaagacaa ttgctgaaaa tccagctaac tataaacgtt
     3421 tgtacgataa tgatctttct gtccaagaaa agattgaaaa aattgtcact gaaatctatc
     3481 gtggtagcaa agtgaacttt gagaagaaag ctcaaacaca aattgctcaa atcgttcaaa
     3541 acggttggga caaattgcca atttgtatgg ctaaaactca atacagtttc tcagacaatc
     3601 caaatgcgct tggagcacca gaaaactttg aaattaccat tcgtgaattg gtaccaaaat
     3661 taggtgcagg cttcatcgtt gccttaactg gtgatgttat gaccatgcca ggtcttccaa
     3721 aacgtccagc agctctcaac atggatgttg aaagcgatgg aactgtgcta ggcttgttct
     3781 agtggattga aattgacttt aagtgagttt ggaaataata tccaagctca ttttttctca
     3841 gactgcaagc agttcatcaa taagatttat actcttcgaa aatcttttca aactacgtca
     3901 gcttcacctt gccgtaggta tatgatactg actctgtcag ttctatccac aacctcaaaa
     3961 cagtgttttg agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
     4021 aagtagatag aaaagttata tactatctat tgaaaatatt ataaatcaga tacaaagaca
     4081 ggtgaaacct tctgtgttat actagagata tgttagattt gaaagaatac ggtatcgtca
     4141 tgtggccgga ggagaaagtc atttctttcc gtgagaaact tctcgcttgg tatgatgaaa
     4201 acaaaagaga tttgccttgg aggagaagta aaaatcctta tcacatctgg gtatctgaaa
     4261 tcatgcttca gcagaccagg gtggatacag ttatccctta ctacgaaaga tttttggact
     4321 ggtttccaac tgtcgaaagt ctggcaactg cgcctgagga gagtttactg aaagcttggg
     4381 agggcttggg ctattattct cgagttcgca atatgcaggc tgcagcccag cagattatga
     4441 ctgactttgg tggccaattt ccaaatacct atgaaggaat ttccagcttg aaagggattg
     4501 gaccttacac agcaggagcc atttccagta ttgcttttaa cttgcctgag ccagctgtag
     4561 atggtaatgt catgcgggtc ttggcgcgtc tgtttgaagt caaccacgat attgggattc
     4621 caagtaatcg aaaaattttt caggcaatga tggagatctt gattaatcca gatcgtccgg
     4681 gtgattttaa tcaagccttg atggacttag ggtctgatat tgagtctcct gtaaatccca
     4741 gacctgaaga aagcccagtc aaggacttta gtgcggcata tcagaatgga accatggacc
     4801 gttatccaat taaatctcct aagaaaaagc cggttcctat ttatcttaaa gccttagttg
     4861 tgaaaaattc tcaaggacaa tttttacttg aaaaaaatga aagcgaaaag ctcttggcag
     4921 gtttttggca tttccccttt atagaagttg ataacttttc gcaagaagag cagtttgacc
     4981 tctttcatca ggttgcggaa gaaagtgtga actctggccc cagtccagaa gagagtttcc
     5041 agcaggacta tgacctagat gttgattggc ttgatgtttg ttttgataca gtccagcatg
     5101 tttttagtca tcgaaaatgg catgtacaga ttgtagcagg tcaggtgagt gacttccatg
     5161 atttttcaga tagggaagtt cgttggcttt caccagaaga attcaagaat tacccacttg
     5221 ccaaacccca acaaaaaatc tggcaggctt atgcacaagc caacttagac agtagccaag
     5281 actagctatt gtgtcttctg actatttttt tggtataata gtagagaaaa aggtgaacat
     5341 atgaaaaaaa tactaattgt agatgatgag aaaccaatct cggatattat caagtttaat
     5401 atgaccaagg aaggttacga agttgtaact gcttttaatg gtcgtgaagc gctagagcaa
     5461 tttgaagcag agcaaccaga tattattatt ctggatttga tgcttccaga aattgatggt
     5521 ttagaagttg ctaagaccat tcgtaagaca agcagtgtgc ccattcttat gctttcagcc
     5581 aaagatagtg aatttgataa ggttatcggt ttggaacttg gggcagatga ctatgtaacg
     5641 aaacccttct ccaatcgtga gttgcaggcg cgtgttaaag ctcttctgcg tcgttctcaa
     5701 cctatgccag tagatggtca ggaagcagat agtaaacctc aacctatcca aattggggat
     5761 ttagaaattg ttccagacgc ctacgtggct aaaaaatatg gcgaagaact agacttaacc
     5821 catcgtgaat ttgagctttt gtatcattta gcatcgcata caggtcaagt catcacgcgc
     5881 gaacacttgc ttgagactgt ctggggttat gactattttg gtgatgtccg tacagttgat
     5941 gtgactgtac gacgtctgcg tgagaagatt gaagatacgc ccagccgacc agagtatatc
     6001 ttgacacgcc gtggtgtagg gtattacatg agaaataatg cttgatttac tgaaacaaac
     6061 catttttacc agagatttta tctttatcct gattttgtta ggtttcatcc ttgttgtgac
     6121 cctcttatta ctggaaaata gacgtgataa tattcagttg aagcaaatca atcaaaaggt
     6181 taaagatttg attgcaggag attattccaa ggttcttgat atgcaaggtg ggtctgaaat
     6241 caccaatatt accaataatt tgaatgactt gtcggaggtt attcgtctca ctcaggaaaa
     6301 tctagaacaa gagagtaaga ggctaaatag tattctgttt tatatgacag atggggttct
     6361 tgcgaccaac cgtcggggtc agattatcat gattaacgat acagccaaga agcaactggg
     6421 gttggttaag gaagatgttc tgaatagaag cattttggaa ttgctcaaga tagaagaaaa
     6481 ctatgaattg cgtgatttga ttacccaaag tccagaattg ttgctagatt cccaagatat
     6541 caatggtgaa tatttgaacc ttcgagttcg ctttgccttg atacgtcgag agtctggctt
     6601 tatttcaggt ttggtggctg ttttgcatga tacgacggag caggagaagg aagaacgcga
     6661 acgaagactc tttgtttcca atgttagcca tgagttacgg actcctctga ctagcgtaaa
     6721 atcctatctt gaagccttgg atgagggggc tttgtgtgaa actgtagcac cagactttat
     6781 caaggtttct cttgatgaga ccaaccgtat gatgcgcatg gtgacggatc tcctccatct
     6841 ttcacgtatt gataatgcta ccagtcacct agatgtggaa ctgattaact tcactgcttt
     6901 tattaccttt atcctcaatc gttttgacaa gatgaaagga caggaaaagg agaaaaaata
     6961 tgagttggtg agagattatc ccatcaattc tatctggatg gaaattgata cagataagat
     7021 gacgcaggtt gtcgacaata ttttaaataa tgctattaaa tattcgccag atgggggtaa
     7081 aatcactgtc agaatgaaga caactgaaga ccagatgatt ttatccattt ctgaccacgg
     7141 tttggggatt cctaagcagg atttaccacg tatctttgac cgtttctatc gtgtggatcg
     7201 tgctagaagt cgtgcacaag gtggtacagg tctaggactg tctatcgcta aagaaattat
     7261 caaacaacat aagggcttta tttgggccaa gagtgaatac ggcaagggtt caacctttac
     7321 cattgtgctc ccttatgata aggatgcagt gaaagaagaa gtatgggagg atgaagtaga
     7381 agactagaat gagtgaaata ggctttaaat acagtatttt agcgtcgggt tccagtggaa
     7441 attcttttta tctggaaacc tcaaaaaata agcttttagt agatgcaggc ttgtctggca
     7501 agaaaattac cagtctgcta gctgaaatta accgtaagcc agaagacctg gatgccatct
     7561 tgattaccca tgagcattca gatcatatcc atggagtagg cgttttggct cgcaagtatg
     7621 gtatggatct ttatgccaat gaaaagacct ggcaagctat ggaaaatagt aaatatcttg
     7681 gcaaggtgga ttcttcgcaa aagcatattt ttgaaatggg taaaaccaaa acctttggag
     7741 atatcgacat cgagagtttt ggtgtaagcc atgatgcagt cgcaccgcag ttctatcgct
     7801 ttatgaagga tgataagagt tttgtccttt tgacagatac aggttatgtc agtgaccgta
     7861 tggcgggcat tgtcgaaaat gcggatggct atcttatcga ggccaaccat gatgtagaga
     7921 ttttgcgatc aggttcttac gcttggcgac tcaaacaacg aatcctatct gaccttggtc
     7981 acctttctaa cgaggacggt gctgaagcta tgattcggac gctaggaaat cgtactaaga
     8041 agatttacct tgggcattta tctaaggaaa ataatatcaa ggaactggct catatgacca
     8101 tggtcaatca gctggctcaa gctgatctgg gagtcggagt agactttaag gtttatgata
     8161 cctcaccaga taccgcaaca ccattgacag agatataaaa agaacgctga gaaggtgttc
     8221 tttttatatt gactgaacac ctaaaaagta atacaatggt gttaccatta aaaaagggag
     8281 cacaaaagat gactactatt acattaaaag tttctgaagc tgataaaaca tttatgaaag
     8341 caatggctaa gtttgaagga gtttcccttt cggaacttat tcgcaccaaa actcttgaag
     8401 ccctagaaga tgaatacgat gctcgtgtgg caaatttagc ctatcaagag tatttagaag
     8461 acttggaaaa aggagttgaa cccattactt gggaagaaat gatgcatgat ttaggcttga
     8521 aggatgaata atttgtataa attagttcca acaagacgtt ttatcaagca attgaaaaaa
     8581 ttggaccgtt atacgcagaa gctaattaca aactatttac aaaccaatgt tttggaaggc
     8641 ccaagacgac acggaaaggc tttggttggt aatcgcgttg gtcaatggcg ctatagaatt
     8701 ggtaattatc gagttatcgt acaaattgta gatgatgaat tagtcgttgc tactctagaa
     8761 gttggtcatc ggagagatat ttattgaatt aaagctgagt aataacaata tagaaagtaa
     8821 ggagagtaaa aatttgaaga aaaaatgctt ttttgcagat tattatgata caacaattat
     8881 tttacttgct ttaatctctg ttattctggt attacttgga tttgctgaga tgattgattt
     8941 ggacaatccg ccttatagta ttattgattt agtaatctgg ggtgtttttg taattgatta
     9001 tagttggcgc ttttttatta ctaaaagaaa atggcgcttt attcttgaaa atatttttga
     9061 tttattggct attctccctt taaatgctat tttcacagtt tttcgattag ggcgtatctt
     9121 tcgtttagtt aaactaacaa aattactgaa actgactcgt ttacttagaa taattggact
     9181 tataggtaaa ttagaaagaa aaattagtag attcttacgg acaaatggcc tgatttatat
     9241 cttatatgtt aatatcttta ttgttctagt agggagttcg attttatccg ttgttgaaga
     9301 aaaatccttc tcagatagtc tctggtgggc tcttgtgacg gtaactactg ttggttatgg
     9361 tgatgttgtt cctacttcaa tttttggtaa atggttagct gtcttattaa tgcttgtcgg
     9421 tattgggaca ataggaatgt taacgagtac cttgacgaac ttttttgtaa aggataatcc
     9481 agatgaacag ataaaacttg ataaactcaa agacgaatta tcgagccaaa gaatattaat
     9541 agagaaacaa tctgaaaaaa tcgaagaact acattgaatg ataaaagact tagttgaaaa
     9601 aatatcataa aggtgagaca aaacaaaact tgattcgagg agaaatcaag taagtcttga
     9661 cacaatagaa cgcatattat caggtataaa aacttgatac tatgcgtttt atagagaaat
     9721 aaaataaaat ctgaacaaat caattaggaa tttaaagcat tttataacaa cgttttagag
     9781 tgatagggtg ctatttcaac ttcaacctac tataatacag aaaaaaaaca actccctgat
     9841 gattcaagga gttgtctata gttaaattag tttttagaag cttcttggaa ttctggattt
     9901 ttccatgctt cgtcaataat agcttgcaat tctttagcag atgcttgcat tttttgagtt
     9961 tctgcatcgt tcaatggaat gtttactgga cgaacgatac catgtgcacc aacaacagct
    10021 ggttgaccga taaagacatt ctcaactccg tattgacctt cttggaatac tgaaagtgga
    10081 agtactgcgt tttcatcgtc aaggattgct ttagtgatac gagcaagggc tactgcgata
    10141 ccgtagtatg ttgcaccttt tttgttgatg attgtgtagg ctgcatcacg aacaccttcg
    10201 aacaattcaa tcaattcagc ttcttgaaca ttttgagtgt ctttaaggaa ttcttcaagg
    10261 tttacaccag cgatgttagc gtgtgaccaa acagcgaact cagagtcacc gtgttcaccc
    10321 atgatgtagg cgtgcactga acgagcatcc acatccaatt tttcagcaag tgcttgacgg
    10381 aaacgagctg agtcaagtga agtacctgaa ccgataacgc gttctttagg gaaaccagag
    10441 aatttccaag ttgagtaagt caaaacgtca actgggttag cagcaacaag gaagatacct
    10501 ttgaaaccag attcaacaac ttgagttacg attgatttgt tgatagcaag gtttttacct
    10561 acaaggtcaa gacgagtttc acctggtttt tgaggtgcac ctgcagtgat cacaacaagg
    10621 tcagcgtctg cacagtcaga gtattgagct gcatagattt ttttaggtga agtgaaggca
    10681 agggcgtgac taaggtcaag cgcatcacca acagcttttt catgcaattg tggaatttcg
    10741 ataattccaa gctcttgtgc aattccttgg ttaacaagtg caaaagcgta agatgaacct
    10801 acagcaccat caccgacaag gataactttt ttgtgttgtt tagttgaagt cattgtttta
    10861 aacatctcct taattttatt aggggatttt ccctagacaa cttcattcta tcacttttaa
    10921 aaaactttgt cacgaatatg ccttatagtt ctcgatgtaa acgttttagt ggtttagagg
    10981 ctgaaataga tgggaattta tggtataatg ttgttactta ctaattgtga aatgaggcat
    11041 ttattaatgc aggataaaaa tttagtgaat gtcaatctga caaaggagat gaaggcaagt
    11101 tttatcgact acgccatgag tgttatcgta gcgcgagctc ttcctgatgt tcgagatggc
    11161 ttaaaacctg ttcaccgtcg cattctctac ggaatgaatg aattgggtgt gaccccagac
    11221 aaaccccata aaaaatctgc tcgtattaca ggggatgtca tgggtaaata tcacccacac
    11281 ggggattcct ctatttatga agccatggtc cgtatggctc aatggtggag ctaccgttac
    11341 atgcttgtag atggtcacgg gaattttggt tccatggatg gagatagtgc tgccgctcaa
    11401 cgttataccg aggcacgtat gagcaagatt gctctggaaa tgcttcgtga tatcaacaaa
    11461 aatacagttg atttcgttga taactatgat gccaatgaac gggaaccctt ggtcttgcca
    11521 gcgcgttttc caaacctttt ggttaatgga gcaactggta tcgcggttgg gatggcaacc
    11581 aatattccac ctcataatct gggtgaaacc attgatgcag tgaagttggt catggataat
    11641 cctgaagtga ctaccaagga cttgatggaa gtcttgcctg gaccagattt tccaactggt
    11701 gctcttgtca tggggaaatc aggtatccat aaggcttatg aaacaggtaa aggttcgatt
    11761 gccctacgtt ctcgtacaga gattgaaacg actaagactg gtcgtgagcg catcgttgta
    11821 acagaatttc cttacatggt caataaaacc aaggtgcatg agcatattgt tcgcttggtt
    11881 caggaaaaac gcattgaggg tatcacagca gtacgtgatg agtcaaaccg tgaaggtgtt
    11941 cgatttgtta ttgaagtcaa gcgcgacgcc tcagccaatg ttattctcaa taacctcttc
    12001 aaaatgaccc aaatgcaaac caattttggt ttcaatatgc tcgctatcca aaatggtata
    12061 ccgaaaattt tgtctcttcg tcagattttg gatgcttata tcgagcacca aaaagaagtg
    12121 gttgttcgtc gtacacgttt tgataaggaa aaagcggaag cgcgcgctca tatcttagaa
    12181 ggtctcttga ttgcgctaga ccatatcgac gaagtgattc gtatcatccg tgctagtgaa
    12241 acggatgcgg aagctcaagc tgagttgatg agcaagttta agctttctga acgtcaaagt
    12301 caagctatcc ttgatatgcg tcttcgtcgt ttgacaggtt tggaacgcga taagattcaa
    12361 tctgagtatg atgacctctt ggctctgatt gcggatttag cagatattct tgctaagcct
    12421 gaacgtgttt ctcaaattat caaagacgaa ttggatgaag ttaaacgtaa attttctgat
    12481 aagcgccgta cagagttgat gattggacag gtcttgagtc tcgaggatga ggacttgatt
    12541 gaagaatcgg atgtcttgat taccctttct aacagaggct acattaagcg tttggatcag
    12601 gacgagttca ctgctcaaaa acgtgggggt cgtggtgtcc aaggaacggg agtgaaagat
    12661 gatgactttg ttcgtgagtt agtgtcaact agcacccatg atcatctgct cttcttcaca
    12721 aacaagggac gtgtctatcg tcttaaaggt tatgaaattc ctgagtatgg tcggactgcc
    12781 aaagggctac cagtagtcaa tctcttgaaa ttggatgaag acgaaagtat tcagacggtt
    12841 atcaatgttg agtctgatcg cagtgatgat gcttatctct tctttacaac ccgtcacggt
    12901 attgtgaaga gaaccagtgt taaggagttt gccaatattc gtcaaaatgg tctcaaagcg
    12961 ctgaatttaa aggatgaaga tgagttaatc aatgtcttgt tggcagaagg agatatggat
    13021 attatcattg gtaccaagtt tggttatgca gttcgcttta atcaatcagc cgttcgtggt
    13081 atgagtcgta tcgccactgg tgtaaaaggt gttaaccttc gtgaaggaga cacagttgtt
    13141 ggtgccagct tgattactga tcaagatgag gttcttatta tcacagaaaa aggatatggt
    13201 aagcgtacag tcgctactga atacccaaca aaaggtcgtg gtggtaaggg aatgcagaca
    13261 gctaaaatta ccgaaaaaaa tggcttgctg gccggtctta tgactgttca aggggatgag
    13321 gatttgatga ttatcactga tacaggtgtc atgattcgaa ccaatcttgc caatatttca
    13381 caaacaggac gtgcaactat gggagttaaa gtaatgcgcc tggatcaaga tgctcagata
    13441 gtgactttca caacggttgc ggtggcagaa aaagaagaag ttgggacaga aaacgaaaca
    13501 gaaggtgaag aataatgtct caaaaaaata ataaaaagaa aaacaagcga aaaaatctgc
    13561 tgacaaatat cctagcagga tttctgatat tactgtcact ggctttgatt tttaatactc
    13621 aaattcgaaa tattttcata gtctggaata ccaataagta tcaagttagc caggtatcaa
    13681 aagaaaaatt agaagaaaat caggatacag aaggcaattt tgactttgat tctgtcaaag
    13741 ctatctcttc ggaagctgtt ctaacttctc aatgggatgc tcaaaaatta ccagttattg
    13801 ggggaattgc aattcctgaa ttggaaatga atttgccgat ttttaaagga cttgataatg
    13861 ttaatctctt ctacggagct ggtacaatga aacgcgagca agtaatggga gaaggaaatt
    13921 atagtctagc tagtcaccat atctttggtg ttgataatgc taataaaatg ttattttctc
    13981 ctttagataa tgctaaaaat ggcatgaaga tttatctaac cgataaaaat aaagtttata
    14041 cttatgaaat acgtgaagtc aaacgtgtga caccggatcg tgttgatgaa gttgatgata
    14101 gagatggggt caatgaaatc acattagtaa cctgtgaaga ccttgctgct acagaacgta
    14161 ttattgtcaa aggtgatttg aaagaaacaa aagattattc acaaacatct gatgaaattc
    14221 taacagcttt caatcaacca tataaacaat tttattaata caaatcagtg aaatcatgga
    14281 tttcactgat tttttaagat tttcataaaa atatagtaaa atgaaataag aataggacga
    14341 atcg
//
LOCUS       DAVBNZ010000053        14208 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000053 DAVBNZ010000000
VERSION     DAVBNZ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.053"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..211
                     /locus_tag="VQ860_001699"
     CDS             <1..211
                     /locus_tag="VQ860_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3120091.1"
                     /translation="PRKSSKLKPLTVEDQAYNHALSKERSKVENIFAKVKTFKMFSTT
                     YRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(526..2217)
                     /locus_tag="VQ860_001700"
     CDS             complement(526..2217)
                     /locus_tag="VQ860_001700"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET3120092.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2353..2799
                     /gene="argR"
                     /locus_tag="VQ860_001701"
     CDS             2353..2799
                     /gene="argR"
                     /locus_tag="VQ860_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3120093.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2850..5384
                     /gene="mutS"
                     /locus_tag="VQ860_001702"
     CDS             2850..5384
                     /gene="mutS"
                     /locus_tag="VQ860_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET3120094.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5531..7225
                     /gene="patA"
                     /locus_tag="VQ860_001703"
     CDS             5531..7225
                     /gene="patA"
                     /locus_tag="VQ860_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET3120095.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDNEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7555..7818)
                     /locus_tag="VQ860_001704"
                     /pseudo
     CDS             complement(7555..7818)
                     /locus_tag="VQ860_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            8016..9782
                     /gene="patB"
                     /locus_tag="VQ860_001705"
     CDS             8016..9782
                     /gene="patB"
                     /locus_tag="VQ860_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET3120096.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMCNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9921..10610
                     /locus_tag="VQ860_001706"
     CDS             9921..10610
                     /locus_tag="VQ860_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3120097.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10614..10793
                     /locus_tag="VQ860_001707"
     CDS             10614..10793
                     /locus_tag="VQ860_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120098.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10780..12129
                     /locus_tag="VQ860_001708"
     CDS             10780..12129
                     /locus_tag="VQ860_001708"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET3120099.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12253..13713
                     /locus_tag="VQ860_001709"
     CDS             12253..13713
                     /locus_tag="VQ860_001709"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET3120100.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYESLGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13727..14161
                     /locus_tag="VQ860_001710"
     CDS             13727..14161
                     /locus_tag="VQ860_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3120101.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4160 a         2749 c         3194 g         4105 t
ORIGIN      
        1 tccacgtaaa tccagcaaac tcaagccact aacagttgaa gatcaagcct ataaccatgc
       61 gctatccaag gagagaagca aggtcgagaa catctttgcc aaagtaaaaa cgtttaaaat
      121 gttttcaaca acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgattgc
      181 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctatta tttggttagg
      241 tgaattagtg aagcgtttag gcaagtgtct ctggttacga cgtcatggcc tctaaatcga
      301 ttatatttag gggtcatgac tagtgaagca gttagctagt tcgcatataa gcggctagcg
      361 tctaacaatt aggaacttta gttccaataa ctttaagatt acgacgtttt aggacataaa
      421 tcgatcatat ttatgtccta aaactagtga agcgcctagc caaagtccga ataggatttg
      481 gcgttagtta cttagattgc tttgcaatca agtaactttg gcgatttaca tcttctctgg
      541 cgcttctact ccaagcaagc gaagggcttc ttttagaacg actgcggttg cgtagctgag
      601 ggctagacgg ctgtcgcgtt ctgggctttc atccaagata cgtgtatgtg catagtattt
      661 gttaaaggat tgagctaggc taattgcaaa tttagcaatg atagaaggtt caaagttatc
      721 tgccgcacgg ttgataatac gtgggaagtc ttgaatgagt ttaatgattt cccagctttc
      781 agtatcattc aagctatagt tgccagctgt ttctggtttg aaatcggctt tgcgtaagat
      841 agattggata cgagcgtagg catattgaac gtaaggtcca gtttcaccct cgaaggatac
      901 catagcttct aggtcgaagt cgtatccatt tgtacggtcg gttttgaggt catagaattt
      961 aatggctcca accccaacag catgtgctac ttggtctttg ttttctagtt caggattttt
     1021 agcctcgatt tggaccttgg cacggctaac agcctctgca acagtaggct ctagcaagat
     1081 gacattccct ttacgagtag agagcttctt cccttccttt gtaaccaaac caaaaggaac
     1141 gtgagtaatg tcgtcactcc agtcgtagcc catctcttgc aagacagctt tgagctgttt
     1201 aaagtgggca gattgttctt gaccaacgac atagatagat ttagcaaatt ggtattcgtt
     1261 tttacggtaa agggctgcag ccaagtcacg tgtgatatag agagttgcac catcagactt
     1321 cttgatgagg gctggatgtt caattccata tttctcaaga ttcacaactt gggcaccttc
     1381 tgattcaaga agtagtcctt tttcagaaag aatgtctaca actgcatcca tcttatcatt
     1441 gtagaaggct tctccgttat agctgtcaaa ttcaaccttc aattcattgt aaaggcggtt
     1501 aaattccact aaactttcat cgcggaacca ttgccaaaga gcgagagctt cctcatctcc
     1561 attttcaagt ttacggaacc attcgcgcgc ttcttcatcc aagctagggt cattttcagc
     1621 ttcagcgttg atgcggacat agagtttaag gagttcatcg attggatgag cttttacagc
     1681 ttcttcgtcg ccccattttt tgtaggcaac aatcaacatc ccaaattgtt taccccagtc
     1741 tcccaaatgg ttgaccttga ccgtttgata accgattttt tggaaaatat gtgacaagct
     1801 atctccgata acagttgaac gcaggtggcc aatagaaaat ggtttagcga tattcggact
     1861 agacatgtcg ataacaacat tttcttgttt gccaatattt tggtcagcat agtgttcttt
     1921 ttcagttgta acagcttgca atacttgagc agaaatggca gatttatcaa ggaaaaagtt
     1981 aacgtaaggt cctgttgcga caactttttc aaaggcttgg ctgttcattt tttcagccag
     2041 ttcagccgca atcatttgtg gtgctttacg ttcgactttg gcaagagaaa aagcagggaa
     2101 agcgatgtca cccatttctg agtttttagg ggtttccagt aactttaaaa tagcctcttg
     2161 gtccaggcta tcaatgatgc tagccaattc gctagcaatc aattcttttg tattcattaa
     2221 gagctccttt ttggactttt ctactatttt aacacaattt taaagaaaga agaaaaaatt
     2281 tttgaaatct cttgtttttt tggtataata tggttataaa tatagttata aatatgcacg
     2341 caagaggatt ttatgagaaa aagagatcgt catcagttaa taaaaaaaat gattactgag
     2401 gagaaattaa gtacacaaaa agaaattcaa gatcggttgg aggcgcacaa tgtttgtgtg
     2461 acgcagacaa ccttgtctcg tgatttgcgc gaaatcggct tgaccaaggt caagaaaaat
     2521 gatatggtgt attatgtact agtaaatgag acagaaaaga ttgatttggt ggaatttttg
     2581 tctcatcatt tagaaggtgt tgcaagagca gagtttacct tggtgcttca taccaaattg
     2641 ggagaagcct ctgttttggc aaatattgta gatgtaaaca aggataaatg gattttagga
     2701 acagttgctg gtgccaatac cttattggtt atttgtcgag atcagcacgt tgccaaactc
     2761 atggaagatc gtttgctaga tttgatgaaa gataagtaag gtcttgggag ttgctctcaa
     2821 gacttatttt tgaaaaggag agacagaaaa tggcgataga aaagctatca cccggcatgc
     2881 aacagtatgt ggatattaaa aagcaatatc cagatgcttt tttgctcttt cggatgggtg
     2941 atttttatga attattttat gaggatgcgg tcaatgctgc gcagattctg gaaatttcct
     3001 taacgagtcg caacaagaat gccgacaatc cgatccctat ggcgggtgtt ccctatcatt
     3061 ctgcccaaca gtatatcgat gtcttgattg agcagggtta taaggtggct atcgcagagc
     3121 agatggaaga tcctaaacaa gcagttgggg ttgttaaacg agaggttgtt caggtcatta
     3181 cgccagggac agtggtcgat agcagtaagc cggacagtca gaataatttt ttggtttcca
     3241 tagaccgcga aggcaatcaa tttggcctag cttatatgga tttggtgacg ggtgactttt
     3301 atgtgacagg tcttttggat ttcacgctgg tttgtgggga aatccgtaac ctcaaggctc
     3361 gagaagtggt gttgggttat gacttgtctg aggaagaaga acaaatcctc agccgccaga
     3421 tgaatctggt actctcttat gaaaaagaaa gctttgaaga ccttcattta ttggatttgc
     3481 gattggcaac ggtggagcaa acggcatcta gtaagctgct ccagtatgtt catcggactc
     3541 agatgaggga attgaaccac ctcaaacctg ttatccgcta cgaaattaag gatttcttgc
     3601 agatggatta tgcgaccaag gctagtctgg atttggttga gaatgctcgc tcaggtaaga
     3661 aacaaggcag tcttttctgg cttttggatg aaaccaaaac ggctatgggg atgcgtctct
     3721 tgcgttcttg gattcatcgc cccttgattg ataaggaacg aatcgtccaa cgtcaagaag
     3781 tagtgcaggt ctttctcgac catttctttg agcgtagtga cttgacagac agtctcaagg
     3841 gtgtttatga cattgagcgc ttggctagtc gtgtttcttt tggcaaaacc aatccaaagg
     3901 atctcttgca gttggcgact accttgtcta gtgtgccacg gattcgtgcg attttagaag
     3961 ggatggagca acctactcta gcctatctca tcgcacaact ggatgcaatc cctgagttgg
     4021 agagtttgat tagcgcagcg attgctcctg aagctcctca tgtgattaca gatgggggaa
     4081 ttatccggac tggatttgat gagactttag acaagtatcg ttgcgttctc agagaaggga
     4141 ctagctggat tgctgagatt gaggctaagg agcgagaaaa ctctggtatc agcacgctca
     4201 agattgacta caataaaaag gatggctact attttcatgt gaccaattcg caactgggaa
     4261 atgtgccagc ccactttttc cgcaaggcga cgctgaaaaa ctcagaacgc tttggaaccg
     4321 aagaattagc ccgtatcgag ggagatatgc ttgaggcgcg tgagaagtca gccaacctcg
     4381 aatacgaaat atttatgcgc attcgtgaag aggtcggcaa gtacatccag cgtttacaag
     4441 ctctagccca aggaattgcg acggttgatg tcttacagag tctggcggtt gtggctgaaa
     4501 cccagcattt gattcgacct gagtttggtg acgattcaca aattgatatc cggaaagggc
     4561 gccatgctgt cgttgaaaag gttatggggg ctcagaccta tattccaaat acgattcaga
     4621 tggcagaaga taccagtatt caactggtta cagggccaaa catgagtggg aagtctacct
     4681 atatgcgtca gttagccatg acggcggtta tggcccagct gggttcctat gttcctgctg
     4741 aaagcgccca tttaccgatt tttgatgcga tttttacccg tatcggagca gcagatgact
     4801 tggtttcggg tcagtcaacc ttcatggtgg agatgatgga ggccaataat gccatttcgc
     4861 atgcgaccaa gaactctctc attctctttg atgaattggg gcgtggaact gcaacttatg
     4921 acgggatggc tcttgctcag tccatcatcg aatatatcca tgagcacatc ggagctaaga
     4981 ccctctttgc gacccactac catgagttga ctagtctgga gtctagttta caacacttgg
     5041 tcaatgtcca cgtggcaact ttggagcagg atgggcaggt caccttcctt cacaagattg
     5101 aaccgggacc agctgataaa tcctacggta tccatgttgc caagattgct ggcttgccag
     5161 cagacctttt agcaagggcg gataagattt tgactcagct agagaatcaa ggaacagaga
     5221 gtcctcctcc catgagacaa actagtgctg tcactgaaca gatttcactc tttgataggg
     5281 cagaagagca tcctatccta gcagaattag ctaaactgga tgtgtataat atgacaccta
     5341 tgcaggttat gaatgtctta gtagagttaa aacagaaact ataaaaccaa gactcactag
     5401 ttaatctagc tgtatcaagg agacttcttt gacaattctc cacttttttg ctagaataac
     5461 atcacacaaa cagaatgaaa aggagctgac gcattgtcgc tcccttttgt ctatttttta
     5521 aggagaaagt atgctgattc agaaaataaa aacctacaag tggcaggccc tggcttcgct
     5581 cctgatgaca ggtttgatgg ttgctagttc acttctgcaa ccgcgttatc tgcaggaagt
     5641 cttaggcgcc ctccttactg ggaaatatga agctatttat agtatcgggg cttggttgat
     5701 tggtgtggcc gtagtcggtc tagttgctgg tggactcaat gttgtcctcg cagcctatat
     5761 tgcccaagga gtttcatccg accttcggga ggatgccttc cgtaaaattc aaaccttttc
     5821 ttatgctgat attgaacaat ttaatgcggg aaatctagtc gttcgaatga caaatgatat
     5881 caaccagatt cagaacgttg tcatgatgac cttccagatt cttttcagac ttcccctctt
     5941 gttcatcggt tcgtttatcc tagcggttca aaccttacct tctctgtggt gggtgattgt
     6001 tctcatggta gtcttgattt ttggtttgac tgctgtcatg atgggaatga tggggcctcg
     6061 ttttgccaag tttcaaaccc ttcttgagcg catcaatgcc attgccaagg aaaatttacg
     6121 tggcgttcgt gtggtcaagt cctttgtcca agaaaaagag caatttgcta agtttacaga
     6181 ggtctcagac gagcttcttg gtcaaaacct ttacattggt tatgcctttt cagtagtgga
     6241 accctttatg atgttggttg gttacggggc ggtcttcctc tctatttggc tggtcgcggg
     6301 aatggttcag tcggatccgt ctgttgttgg ttccatcgct tcttttgtta attacctaag
     6361 ccagattatc tttaccattg ttatggttgg atttttggga aattctgtca gccgtgccat
     6421 gatttccatg cgtcgtattc gagaaattct tgacgcagag ccagctatga ccttcaagga
     6481 tatcccagat gaagagttgg ttggaagcct tagctttgaa aatgtgacct ttacctatcc
     6541 aatggacaat gaaccgatgc tgaaagatgt gagctttact attgaacctg gtcaaatggt
     6601 tggtgtagtt ggagcgactg gtgcaggaaa gtcaaccttg gctcaattga ttccacgtct
     6661 ctttgatcca cagaacgggg ccattaaaat cggtggcaag gatattcgag aagtgagtga
     6721 aggaaccctg cgtaaaacag tttccatcgt tctccaacgt gccattcttt ttagtggaac
     6781 gattgcagat aacttgagac aggggaaggg aaatgctact ctatttgaaa tggagcgcgc
     6841 agccaatatt gcccaggcta gtgaattcat tcatcgtatg gagaaaacct ttgaaagtcc
     6901 agttgaagaa cggggaacca atttctctgg tggacaaaaa caaaggatgt cgattgcgcg
     6961 tgggattgtc agcaatccac gtattctgat ttttgacgat tcgacctcag ccttggatgc
     7021 caaatcagag cgcttggtgc aagaagcttt gaataaggac ttgaagggga cgacaaccat
     7081 tattattgct caaaaaatta gctcggttgt ccatgcagac aagatcttgg ttctaaatca
     7141 aggacgattg attggtcaag gcacgcatgc agacttggtt gccaacaatg ccgtttaccg
     7201 tgaaatctat gaaacacaga aatgaaagac aaactataag aaaagtcaat agttttatct
     7261 aaattatttc ttatttcaat ttgatgattt ggcgatgatt ttagagcacg gcaaaaagcc
     7321 cttgaaaaag tccatttttt caaaggtaat cctgtgttga tttcagaaat tacatcactt
     7381 tttgttcgtc aaatggcagc tcttttttag gatataaaac agggttcgga taagtttttt
     7441 tgtaaggtgg atgatggcta cattgtaatg ttttccttat tctaacttag tcttaagata
     7501 ggccttaaaa gcaggtgaaa agcgagggca tgctttggca gcttgtatga gtgcctaccg
     7561 cagatgaggg gaaccccgtt tgatcattct tccagctaaa tcaatctgat ctgactgata
     7621 aatagaagaa tccagtccag cgaaagcttg taattgagca ggattatcaa aggcatgaat
     7681 attttgaatc tcggctaaaa tgaccgcccc taaacgattc ccaatcccag taaccgtcgt
     7741 gatgatcgag ttgaactcag ccatcaagtc attgacacat gtttccgcct tgtcaatgag
     7801 cctcttgtaa tgtttgatgt tttcattaca cgagataaaa cgtttatgcg ttatcaaact
     7861 catgaccaat tgaaacaaaa agctgtggtt agatcctttc ggaaattgtc aagcgattgg
     7921 aggaaatgaa ctaatccaca gcggcttatt ccaagtatac cacttgggct ttggcagtag
     7981 ctaactgcgc taaatataat ataaggagga gtaaaatgaa gacagttcaa tttttttggc
     8041 attattttaa ggtttacaag ttctcatttg tagttgtcat cctgatgatt gttctggcga
     8101 cttttgccca agccctcttt ccagtctttt ctggacaagc ggtgacgcag ctagccaatt
     8161 tagttcaagc ttatcaaaat ggcaatccag aacttgtatg gcaaagccta tcaggaatca
     8221 tggtcaatct tggcctgctg gttttggttc tatttatctc tagtgtaata tacatgtgtc
     8281 tcatgacgcg cgtgattgca gaatcgacca acgagatgcg caaaggcctc tttggtaagc
     8341 ttgctcagtt gacggtttct ttctttgacc gtcgacaaga tggcgatatc ctgtctcatt
     8401 ttaccagtga tttggataat atcctccaag cctttaacga aagcttgatt caggtcatgt
     8461 gcaatattgt tttatacatt ggtctgattc ttgtcatgtt ttcgagaaat gtgacgctgg
     8521 ctctcatcac cattgccagc accccattgg ctttccttat gctgattttc atcgtgaaaa
     8581 tggcacgcaa atacaccaac ctccagcaga aagaggtagg gaagctcaac gcctatatgg
     8641 atgagagcat ctcaggccaa aaagccgtga ttgtgcaagg aattcaagag gatatgatgg
     8701 caggatttct tgaacaaaat gagcgcgtgc gcaaggcaac ctttaaagga agaatgttct
     8761 caggaattct tttccctgtc atgaatggga tgagcctgat taatacagcc atcgtcatct
     8821 ttgctggttc ggctgtactt ttgaatgata agtctattga aacaagtaca gccctaggtt
     8881 tgattgttat gtttgcacaa ttttcacagc agtactacca gcctattatc caagttgcag
     8941 cgagttgggg aagccttcag ttggccttta ctggagctga acgaattcag gaaatgtttg
     9001 atgcagagga ggaaatccga cctgaaaagg ctccaacctt cactaagttg caagaaagtg
     9061 ttgaaatcag tcatatcgat ttttcatact tgcctgataa acctattttg aaagatgtca
     9121 gcatttctgc ccctaaaggc cagatgacag cagttgttgg gccgacaggt tcaggaaaaa
     9181 cgactattat gaacctcatc aatcgctttt atgatgttga tgctggtggt atttattttg
     9241 atggtaaaga cattcgtggc tatgacttag atagtcttag aagcaaggtg ggaattgtat
     9301 tgcaagattc ggtcttgttt agcggaacga ttcgagacaa tatccgattt ggtgtgccag
     9361 atgctagtca ggaaatggtt gaggtagcag caaaagcaac ccacattcac gactatatcg
     9421 aaagtttgcc tgataagtac gatactctta ttgatgatga ccagagcatc ttttcaacag
     9481 ggcagaagca attgatttca atcgctcgaa ccctgatgac agatccagaa gttctcattc
     9541 tcgatgaagc aacttcaaac gtagatacgg tgacagaaag caagattcag catgccatgg
     9601 aggtggttgt agcaggtaga actagtttcg tcattgccca ccgcttgaaa accattctca
     9661 atgcagatca gattattgtc cttaaagatg gagaagtcat tgaacgtggt aaccaccatg
     9721 aacttttgaa gctaggtggc ttttattcag aactctatca caatcaattt gttttcgaat
     9781 gagaaagaag ttgtcctatg tgggcagctt tttcttgtcc ataaaaaatg tttatcacag
     9841 ccttaaaaaa aacatattag acgaaagtca ttttgagtga tatgatagga ctatcgttag
     9901 cattcgaaag gagaggcatc atggctagaa cggttgtagg agttgctgca aatctatgtc
     9961 ccgtagacgc agaaggcaaa atcattcatt catctgtatc ttgtagattc gcagagatca
    10021 ttcgtcaagt cggtggtctc cctttagtca ttcctgttgg tgatgagtca gttgtacgtg
    10081 attatgtgga aatgattgac aaactcattt tgacaggagg ccaaaatgtt catcctcagt
    10141 tttatggaga gaaaaagacc gtcgagagcg atgattacaa tctggtccgt gacgaatttg
    10201 aattggcact cttgaaggaa gcgcttcgtc agaataaacc aattatggca atctgtcgcg
    10261 gtgtccaact tgtcaatgtt gcctttggtg gaaccctcaa tcaagaaatc gaaggtcact
    10321 ggcaaggact acctttcggg acatctcact ctattgagac agtagaagga agcgtggtgg
    10381 ctaagctatt tgggaaagaa agtcaggtca attcagtcca tcgtcaaagc attaaagatt
    10441 tggcacccaa tttccgtgta actgctattg attcaagaga ccaaactatt gaagcgattg
    10501 agtctatcga cgagcaccgc attatcggtt tacagtggca tccagagttt ctggttaatg
    10561 aagaagatgg caatttagaa ttatttgagt atttattgaa tgaactgtaa cgattggaac
    10621 atctggtcgt tctttctttt attttttcaa aatttttaga atgtggtatt ttacgcaaac
    10681 gtttgaattc tgataaaaat tggagaaatt cgacaaaaaa acttgaaaaa aacgaaggta
    10741 agcgttatga tagaaaagaa gaaatattgg aggaagaaca tgtcacatat taaatttgat
    10801 tattcaaaag ttttagacaa atttgttgca ccacatgaag tggaatacat gcaatcacaa
    10861 gtaacagcag cagatgaatt gatccgtaaa ggaactggtg ctggtagcga cttcttggga
    10921 tggttggacc ttcctgaaaa atacgaccgc gaagaatttg accgcatctt gaaagctgct
    10981 gagcaaatca agtcagacag cgatgttttg gttgtgatcg gtattggtgg atcttacctt
    11041 ggtgcaaaag cagcaatcga cttcttgaat caccattttg ctaacttgca aacaaaagaa
    11101 gaacgcaaag ctccacaaat cctttacgca ggaaactcaa tctcatctac ttaccttgct
    11161 gacttggtag agtatgttgc agacaaagac ttctcagtaa acgtaatttc taaatcaggt
    11221 acaacaactg aaccagcgat tgctttccgt gtctttaaag aactcttggt taagaaatac
    11281 ggtcaagaag aagctaacaa acgtatctat gcaacaactg accgccaaaa gggtgctgtt
    11341 aaggttgaag cagacgctaa cggttgggaa acatttgttg ttccagatga tatcggtgga
    11401 cgcttctcag tattgacagc cgttggtttg cttccaatcg cagcatcagg agctgacatc
    11461 aaagctctta tggaaggtgc gaatgcagct cgcaaagact acacttcaga caaaatctct
    11521 gaaaacgaag cttaccaata cgcagctgtt cgtaacatcc tttatcgtaa aggctatgca
    11581 actgagatct tggtaaacta tgagccatca cttcaatact tctcagaatg gtggaaacaa
    11641 ttggctggtg aatcagaagg aaaagaccaa aaaggtatct acccaacttc agccaacttc
    11701 tcaactgact tgcactcact tggtcaattt atccaagaag gaactcgtat catgtttgaa
    11761 acagttgtcc gtgttgacaa acctcgtaaa aacgtgctta ttcctacttt ggaagaagac
    11821 cttgacggac ttggttacct tcaaggaaaa gacgttgact ttgtaaacaa aaaagcaact
    11881 gacggtgttc ttcttgccca cacagatggt gatgtaccaa acatgtatgt gactcttcca
    11941 gagcaagacg ctttcactct tggttacact atctacttct tcgaattggc aattgccctt
    12001 tcaggttact tgaatgctat caacccattt gaccaaccag gtgttgaagc ttataaacgt
    12061 aacatgtttg cccttcttgg aaaaccagga tttgaagaat tgagcaaaga acttaacgca
    12121 cgtctataat agaagaaaag agtggtttac ccactctttt tactctcttt atccatagaa
    12181 attggactca gtcaagactt gtgatataat atagaaagca aaaaggcaga tgcctagata
    12241 ataggagaaa ctatgtcaaa agatatccgc gtacgttacg caccaagtcc aacaggacta
    12301 ctacacatcg gaaatgctcg tacagcattg tttaattact tgtatgcgcg ccatcatggt
    12361 ggaacatttc tcatccgtat cgaagatact gaccgtaaac gccatgtcga ggatggtgaa
    12421 cgttcacaac ttgaaaacct tcgctggtta ggcatggatt gggatgaaag tccagaatca
    12481 catgagaatt atcgccagtc tgagcgttta gacttgtatc aaaaatacat tgaccaacta
    12541 ttagctgaag gaaaagccta taaatcttac gttacagaag aagagttggc agctgaacgc
    12601 gaacgccaag aagtagctgg cgaaacacca cgctacatca atgaatacct tggtatgagt
    12661 gaagaagaaa aagcagctta catcgcagaa cgtgaagcag cagggatcat cccaactgtt
    12721 cgtttggctg tcaatgagtc aggtatctac aagtggcatg atatggtcaa aggcgatatc
    12781 gaatttgaag gtggcaatat cggtggtgac tgggttatcc aaaagaaaga cggttaccca
    12841 acttacaact ttgccgttgc catcgatgac cacgatatgc aaatctctca tgttatccgt
    12901 ggagatgacc atattgctaa tacaccaaaa cagcttatgg tctatgaatc tcttggttgg
    12961 gaagctccag agttcggtca catgaccttg attatcaact ctgagactgg taagaagtta
    13021 tctaaacgtg atactaatac acttcaattt atcgaagatt accgaaagaa aggttacctt
    13081 ccagaagcag tctttaactt tattgctctt cttggttgga acccaggtgg tgaagatgag
    13141 attttctctc gtgaagaact cattaaactt tttgatgaaa accgcctcag caagtcacca
    13201 gcagcctttg atcagaaaaa actagactgg atgagcaatg attatatcaa gaatgcagac
    13261 cttgaaacca tctttgaaat ggcaaaacca ttcttagagg aagcaggccg tttgactgac
    13321 aaggctgaaa aattagttga gctctataaa ccacaaatga aatcagtaga tgagattatc
    13381 ccattgacag atcttttctt ctcagatttc ccagaattga cagaagcaga gcgcgaagtc
    13441 atgacgggtg aaacagttcc aacagttctt gaagcattca aagcaaaact tgaagcgatg
    13501 acagatgata aatttgtgac agaaaatatc ttcccacaaa ttaaagcagt tcaaaaagaa
    13561 acaggtatta aagggaaaaa tcttttcatg cctattcgta tcgcagtttc aggcgaaatg
    13621 catgggccag aattaccaga tacaattttc ttgcttggac gtgaaaaatc aattcagcat
    13681 atcgaaaaca tgctaaaaga aatctctaaa taaagaggat acaataatgg acatctggga
    13741 aaagatgtac gaagaagcac agaaactata caatccacat gaagtatcag actttgttta
    13801 tgccaatcat gttgtagctg cagtagaagc agaagatgga caaatattta caggattctg
    13861 tatggaggga acctgtggtg ttttccatct ctgcgcagaa cgggcggccc tcttcaatat
    13921 gtaccaattt tcaggacaaa ctaaggttaa gaaagtatta gcctttcgag acaaaccacc
    13981 ttatggtgga agttcagcca tgccttgcgg tgcttgtaga gaattccttt tagagcttaa
    14041 tgctgaaaat aaagatgcag aattcatgat ggactataat ataagaaaaa cagttaaagt
    14101 cgcagaacta atcccttatt ggtggggaga agaacgtgct tctaagttta atgagcgata
    14161 gaagagtcag tataattttg gctcttttta ctataagttg aaaaaata
//
LOCUS       DAVBNZ010000054        13176 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000054 DAVBNZ010000000
VERSION     DAVBNZ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.054"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            276..890
                     /locus_tag="VQ860_001711"
     CDS             276..890
                     /locus_tag="VQ860_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET3120102.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAILRLVF"
     gene            994..1824
                     /locus_tag="VQ860_001712"
     CDS             994..1824
                     /locus_tag="VQ860_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3120103.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            1978..2832
                     /locus_tag="VQ860_001713"
     CDS             1978..2832
                     /locus_tag="VQ860_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3120104.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            2932..4305
                     /locus_tag="VQ860_001714"
     CDS             2932..4305
                     /locus_tag="VQ860_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET3120105.1"
                     /translation="MFFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLCGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4298..5359
                     /locus_tag="VQ860_001715"
     CDS             4298..5359
                     /locus_tag="VQ860_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET3120106.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5361..6053
                     /locus_tag="VQ860_001716"
     CDS             5361..6053
                     /locus_tag="VQ860_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3120107.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6083..6652)
                     /locus_tag="VQ860_001717"
     CDS             complement(6083..6652)
                     /locus_tag="VQ860_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3120108.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            6787..7401
                     /locus_tag="VQ860_001718"
     CDS             6787..7401
                     /locus_tag="VQ860_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3120109.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7403..9049
                     /locus_tag="VQ860_001719"
     CDS             7403..9049
                     /locus_tag="VQ860_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3120110.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGNTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRNFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9061..10347
                     /locus_tag="VQ860_001720"
     CDS             9061..10347
                     /locus_tag="VQ860_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3120111.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQAWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRIPITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10399..10932
                     /locus_tag="VQ860_001721"
     CDS             10399..10932
                     /locus_tag="VQ860_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3120112.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRVAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11010..11480
                     /gene="nrdI"
                     /locus_tag="VQ860_001722"
     CDS             11010..11480
                     /gene="nrdI"
                     /locus_tag="VQ860_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET3120113.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHLYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11773..13035)
                     /locus_tag="VQ860_001723"
     CDS             complement(11773..13035)
                     /locus_tag="VQ860_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET3120114.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3901 a         2452 c         3007 g         3816 t
ORIGIN      
        1 tatcttattt caatctgcta tataatagtc catgctatgg ctggattctt ttcagtctac
       61 ttatactctt cgaaactctc ttcaaaccac gtcagcttca ccttgccgta gtacggttac
      121 tgacttcgtc agttctatcc acaacctcaa aacggtgttt tgagcaacct gcggctagtt
      181 tcctagtttg ctctttgatt ttcattgagt attattaaga caatatgagg agaaagatga
      241 aagaaaaagg attttaggag ggggcgcagg cagccatgcc aacggctctt ggctatgtca
      301 gtatcggcct ggcctgtggg actatcggtg cgccctatgt gacacctgtt gagatgggct
      361 tgatgagtct ctttgtttat gctgggagtg cccagtttgc catgttggca ctgattgtgg
      421 ttcaagctcc tgtggcagct attgctatga cggtttttct aatcaacttg cgtctctttt
      481 tgttgagttt acacgcatcg acttatttcc gtcataccag tctttggtac aatatcggta
      541 tgtctagtat cttgacagat gagacctatg gcgttttgat gggtgaattg gcccatacag
      601 acaaggtaaa tcctatgtgg atgcacggaa acaatcttaa cagctatgtg gcttggtttg
      661 tggggacagt agtcggaacg gctctgggtg gcctgctacc aaatccagaa atctttgcct
      721 tgattctttc aagcgtagtg acaggtaagg ttgggagcct tcctcaaatt aaatggctag
      781 acttcttagc cgtctttcca acagcttggg tagcctttcg ctaccgcaat ctagtcggaa
      841 cagttctctt tggagtggtc ttgattgcca tcttgcgttt ggtcttttaa attacccata
      901 aaaaaaactt atcacagaga tagatatcat ataatggcgt aaatgctctt tttctgttaa
      961 gattataagg tattctattt tggaggaaat gacatgaaaa aaatcgttaa atactcatct
     1021 cttgctgccc taggacttgt tgctgcaggt gtgcttgcgg cttgctcagg gggtgctaag
     1081 aaagaaggag aagcagctag caagaaagaa atcatcgttg caaccaatgg atcaccaagg
     1141 ccatttatct atgaagaaaa tggcgaattg actggttacg agattgaagt cgttcgcgct
     1201 atctttaaag attctgacaa atatgatgtc aagtttgaaa agacagaatg gtcaggtgtc
     1261 tttgctggtc ttgacgctga ccgttacaat atggctgtca acaatcttag ctacactaaa
     1321 gaacgtgcgg agaaatacct ctatgccgca ccaattgccc aaaatcctaa tgtccttgtc
     1381 gtgaagaaag atgactctag tatcaagtct ctcgatgata tcggtggaaa atcgacggaa
     1441 gtcgttcaag ccactacatc agctaagcag ttagaagcat acaatgctga acacacggac
     1501 aacccaacta tccttaacta tactaaggca gacttccaac aaatcatggt acgtttgagc
     1561 gatggacaat ttgactataa gatttttgat aaaatcggtg ttgaaacagt gatcaagaac
     1621 caaggtttgg acaacttgaa agttatcgaa cttccaagcg accaacaacc gtacgtttac
     1681 ccacttcttg ctcaaggtca agatgagttg aaatcatttg tagacaaacg catcaaagaa
     1741 ctttataaag atggaactct tgaaaaattg tctaaacaat tcttcggaga cacttatcta
     1801 ccggcagaag ctgatattaa ataatttctt gaaatcatcc attctgagta aggtgggtgg
     1861 tttctcagtt tttagggata tagttttaaa ctatatatct gactatctaa taacaatttg
     1921 tgaaatcaaa caaattgtga gatactagta cggtattatt tttaaggaga aagaatcatg
     1981 aaaatcaaaa aatggcttgg tctagcagcc cttgctacag tcgcaggttt ggctcttgca
     2041 gcttgcggaa actcagaaaa gaaagcagac aatgcaacaa ctatcaaaat cgcaactgtt
     2101 aaccgtagcg gttctgaaga aaaacgttgg gacaaaatcc aagaattggt taaaaaagac
     2161 ggaattacct tggaatttac agagttcaca gactattcac aaccaaacaa agcaactgct
     2221 gatggcgaag tagatttgaa cgctttccaa cactataact tcttgaataa ctggaacaaa
     2281 gaaaacggaa aagaccttgt agcgattgga gatacttaca tctctccaat ccgcctttac
     2341 tcaggtttga atggaagtgc caacaagtac actaaagtag aagacatccc agcaaacgga
     2401 gaaatcgctg taccgaatga cgctacaaac gaaagccgtg cgctttactt gcttcaatca
     2461 gctggcttga ttaaattgga tgtttctgga actgctcttg caacagttgc caacatcaaa
     2521 gaaaatccaa agaacttgaa aatcactgaa ttggacgcta gccaaacagc tcgttcattg
     2581 tcatcagttg acgctgccgt tgtaaacaat accttcgtta cagaagcaaa attggactac
     2641 aagaaagcac ttttcaaaga acaagctgat gaaaactcaa aacaatggta caacatcatt
     2701 gttgcgaaaa aagattggga aacatcacct aaggctgatg ctatcaagaa agtaatcgca
     2761 gcttaccaca cagatgacgt gaaaaaagtt atcgaagaat catcagatgg tttggatcaa
     2821 ccagtttggt aataagaaac agggaggtgg gagagaaaat tccacctctt gcttttgtat
     2881 agagtataga ttgtaaagaa gactattcgt tcatagaaag gtagagagaa tatgtttttt
     2941 cctagcgaac aagaacagat tgaaaaattt gaaaaggatc atgtagccca gcattatttt
     3001 gaggttttgc gtaccttgat ttctaagaaa tcagtctttg cccagcaggt tggactcaag
     3061 gaagtcgcaa actatctggg tgagattttc aagcgtgttg gagctgaagt ggagattgat
     3121 gagagctata cagcgccctt tgtcatggca catttcaaga gttcgcgtcc agatgccaag
     3181 accttgattt tctataacca ctatgacact gtgccagcgg atggggatca ggtctggaca
     3241 gaggatcctt ttacgctttc ggtccgcaat ggcttcatgt atgggcgtgg ggttgatgac
     3301 gacaagggtc atatcacagc tcgcttgagt gctttgagaa aatatatgca gcaccatgat
     3361 gatttacctg tcaatatcag ctttatcatg gagggagcgg aggaatcggc ttcaacagac
     3421 ctagataagt atttggaaaa gcatgcagac aaactctgtg gggcggattt gttggtctgg
     3481 gaacaaggga ccaaaaatgc cttggaacag ctggaaattt ctggtggcaa taagggaatt
     3541 gtgacctttg atgccaaggt aaaaagcgct gatgtggata tccactcgag ttatggtggt
     3601 gttgtggaat cagctccttg gtatctcctc caagccttac agtctcttcg tgctgcggat
     3661 ggccgtatct tggttgaagg cttgtacgaa gaagtacaag agcccaatga acgagaaatg
     3721 gccttgctag aaacttatgg tcaacgaaac ccagaggaag ttagtcggat ttatggattg
     3781 gagttgcctc tcttacagga ggagcggatg gcctttctaa aacgtttctt tttcgagcca
     3841 gcgcttaata tcgaaggaat ccagtctggt tatcaaggtc agggtgttaa gactatttta
     3901 cctgcagaag ccagtgcaaa gctagaggtt cgtctggttc cgggcctaga accgcatgat
     3961 gttctggaaa aaattcggaa acaactagac aaaaatggct ttgataaggt agaattatac
     4021 tataccttgg gagagatgag ctatcgaagc gatatgagcg caccagccat tctcaatgtg
     4081 atcgagttgg ccaagaaatt ctatccacag ggtgtttcag tcttgccgac gacagcgggg
     4141 acaggaccta tgcatacggt ctttgatgcc ctagaggtac caatggttgc attcggtcta
     4201 ggaaatgcca atagccgaga ccacggtgga gatgaaaatg tgcgaatcgc tgattattac
     4261 acccatatcg aattagtaga ggagctgatt agaagctatg agtagagata ttatcaagtt
     4321 agatcagatc gatgtgactt ttcaccaaaa gaagagaacc attacagcgg ttaaggatgt
     4381 gaccattcac atccaagaag gggatatcta cggaatcgtt ggatattctg gagcaggaaa
     4441 atcaaccctt gtacgggtga ttaacctctt gcaaaaacca tctgcaggga aaattaccat
     4501 tgacgacgat gtgatttttg atggtaaggt caccttgacg gcagagcagt tgcgtcgtaa
     4561 acgtcaagat atcgggatga ttttccagca ttttaacctg atgagccaaa agacagcaga
     4621 ggagaatgta gcctttgccc ttaaacactc tggactcagc aaggaagaaa agaaggctaa
     4681 agtagctaag ttgttggact tggttggttt ggcagatcgt gctgaaaact acccttcaca
     4741 attatctgga gggcaaaaac agcgtgtggc aattgcgcgt gccttggcca atgatccaaa
     4801 aatcttgatt tcagacgagt caacttctgc ccttgaccct aagacaacca agcagatttt
     4861 ggccttgttg caagatttga accaaaaatt aggcttgact gttgtcttga ttacgcatga
     4921 aatgcagatt gtcaaagaca ttgccaaccg tgttgcagtt atgcaggatg ggcatttgat
     4981 tgaagagggt agtgtgcttg aaatcttctc aaaccctaaa caacctttga ctcaagactt
     5041 tatctcaaca gctacaggta ttgacgaagc catggtcaaa atcgagaagc aagaaatcgt
     5101 ggaacacttg tctgaaaaca gtctcttggt gcaactcaag tacgctggag cttcaacaga
     5161 cgagccactt ttgaatgaat tgtacaagca ttaccaagta atggctaata ttctctatgg
     5221 gaatatcgaa attctcgatg gtactcctgt tggagaattg gtggtggttt tgtcaggtga
     5281 aaaagcagcg ttggcaggtg cccaagaagc cattcgtcaa gcaggtgtac aactaaaagt
     5341 attgaaggga gtacagtaag atggaatcat tgattcaaac ctatttacca aatgtctata
     5401 agatgggttg ggctggtcag gcaggctggg gaacggctat ctacttaact ctttatatga
     5461 cagttctttc cttcattatc ggaggcttct tggggctagt ggcaggtctc tttctcgtct
     5521 tgacagcgcc aggtggtgtc ttggagaata aagtcgtatt ctggatttta gacaaaatta
     5581 cctcaatttt tcgtgcggtt ccctttatca tcctcttggc aatcttgtca ccactttctc
     5641 acttgattgt taaaacaagt atcgggccaa atgcagccct tgtcccactt tcttttgcag
     5701 tctttgcctt ctttgcccgt caggtgcagg ttgtcttggc tgaattggat ggcggtgtca
     5761 ttgaggcggc tcaagcgagc ggagcgactt tctgggacat cgtgggtgtt tacctatcag
     5821 aaggtcttcc agatttgatc cgtgtgacga ctgtgacctt gatttccctt gttggggaaa
     5881 cagctatggc cggtgcggtt ggagctggtg gtatcggtaa cgtagccatc gcttatggat
     5941 ttaaccgcta caatcacgat gtgaccatct tggcaaccat tattatcatt ttgattatct
     6001 ttgcaatcca attcttggga gatttcttga ctaagaaatt gagccataaa taaaaaagag
     6061 ccgcgtggct ctttttaact gatcagattt tctgtgcaaa ttttttactc aaggcttgtc
     6121 caatcaaagc acccactagg gctccgatga caatacttgc gataaataga aggacagttc
     6181 cagggtttgg agcgaccatg atacggtcga tatattcttg ggattttcct cttgccagaa
     6241 gagtagccat ataggctttg ggcgcaatcc acataagcaa gattggtcct gttgtactaa
     6301 aggcgaaaat aatgaaagaa aggaagttct ttgttttgtc cttgtatttt cctaaatgag
     6361 ctacttcatc tgctaggagg ccacagataa ttccaggaag gaaggaacca gcaccgtgtt
     6421 tagttcccaa gaaaaagaag gcaatgacaa ggccgatagt ggtaatggct ccaaagcgcg
     6481 gaacttttgc gactaggatc atatagacgc taccgccgac aagggcagta aaggcaggcg
     6541 cataaaacat gtttccagtt tggtcaaaga gattgcccaa aaggacacca atccccatgc
     6601 agaggaagta aagaactgca aaaagcagtg tagttaagat agatttcttc atgaattgtc
     6661 tcctgataat tttttcacaa ttctcatttt accatggttt ggtgggattg taaatggata
     6721 ctagaagttt ttgaaaacgc ttgaaatatg atataatggt ttcatagtta tttttagggg
     6781 aatatcatgg gtagattttt agactttgtc tttaatcgtt tctttttagg gatgattgcg
     6841 acagccttct tttggctatt aactttagca ggagggatta tccttggtct agcgccggct
     6901 agtgccacct tgatgagctt atatgcagaa catggttata gctttcggga atacagtttg
     6961 aaggaggctt ggtctcttta caagcaaaat tttgtctcaa gcaacctgat tttctatagc
     7021 tttttaggtg tgggtctagt tttgacctat ggtttgtatc tcttggtgca attgcctcat
     7081 cagaccattg ttcatttgat tgcgaccctt ttgaatgtct tagtagttgc cctgatcttt
     7141 ttggcttata cagtatcttt aaaattacaa gtttattttg ccttgtccta tcgaaatagt
     7201 ctcaaattat ccttgattgg catctttatg agtctagcag ctgtggccaa ggttctcctt
     7261 gggactgtgc tacttgtagc aattggttac tatatgcctg ccctgctatt ttttgtagga
     7321 attgggatgt ggcatttctt tatcagtgat atgttggaac ctgtctatga aatcatccat
     7381 gaaaaattgg cgacaaaata gaatgaagca gttttggcta catacgcttc taagaaccta
     7441 tagttcagtg atgatcatta tcattgcgag ttttgcaatc ttactctctt acgctgactg
     7501 ggattcacgt gaaaaggaag cccagagagt agcccagcgt gtaactgcta gaacagtgag
     7561 tgaaattgaa tattaccata gagagtcaac ccagatagct caggctttag ttgaaaatca
     7621 agctcgtatt gagggaatct ataaatactt tagccttagc atgccagact atttttactg
     7681 gcaattagag cggaaagctt cgccttatat atcagtctct ctgtatgaaa atgttgatga
     7741 cctctatgtt cgaaatgatt ttgtaactgg agtggccatt gcttttcaag attacaagga
     7801 agtctatgtt tctactaaag acaaacgtag tggagaaaaa atcagggctg aggatttcaa
     7861 accagcagga aatagttttg ccattccggt gtcagatcca gtgtcagatc aagatttagg
     7921 agtgatttac atctccttgg atcctgctgt tttataccat gccattgata atactagagg
     7981 taatactccg atggcagtaa cagtgacctc accttttgat acggagattt ttcatattgg
     8041 tgagacagtt gataaggaga gtgaaaattg gctagttggc ttaacttctc atggatatca
     8101 ggttcaggtg gcagttccta aaaactttgt tttacaagga acagtgacta gctctgcttt
     8161 gattgtgggt ttgagccttc tctttattgt cattctttat ctgactttga ggcagacttt
     8221 tgctaattac caaaagcagg tagtggattt agtagaatcc attcaagtca ttgctcaagg
     8281 cgaagagggt cgtcggattg acatttccga gaaagatcag gaattactcc taatcgcgga
     8341 gacgaccaat gatatgttgg atcgattgga aaagaatatc catgatattt accagttaga
     8401 gcttagtcaa aaagatgcta atatgcgagc cttgcaggcg caaatcaatc ctcattttat
     8461 gtataatacg ctggagttct tgcgcatgta tgcagttatg cagagtcaag atgagttggc
     8521 agatatcatt tatgaattca gtagtctctt gcgtaacaat atttccgacg aaagagagac
     8581 cctcctcaaa caggaattag aattttgccg taaatacagc tatctctgca tggttcgcta
     8641 tcccaagtcc attgcctatg gtttcaagat agatccagag ttagagaata tgaagattcc
     8701 taagttcacc ttgcaaccgc tggtagaaaa ttatttcgcg catggtgttg accacaggcg
     8761 gacagataat gtgattagca tcaaggctct taaacaggat ggttttgtgg aaattttggt
     8821 ggtcgataat ggtagaggaa tgtcggctga aaagttggca aatatccgag aaaaattaag
     8881 tcagagaaat tttgaacacc aagccagcta cagtgatcaa aggcagtcta tcgggattgt
     8941 caatgtacac gagcgttttg tgctctattt tggagaccgc tatgccatta ctatagagtc
     9001 tgcagagcaa gccggtgttc agtatcgtat tacaattcaa gatgagtaga aagggagaaa
     9061 atgtataaag tattattagt agatgatgag tacatggtga cagaaggtct gaagcgtttg
     9121 attccctttg ataagtggga tatggaggtc gtcgcaacag ccagtcatgc cgatgaagct
     9181 ctagaatatg ttcaggaaaa tcctgtcgat gtcatcattt ccgatgtcaa tatgccagac
     9241 aaaacagggc ttgatatgat tcgggagatg aaagagatct taccagatgc tgcctatatc
     9301 ctgctctcag gttatcagga gtttgattat gtaaaaagag caatgaacct tagtgtggtg
     9361 gactatttgg tcaaacctgt tgataaggta gagctgggaa atctgctgga gaagattgca
     9421 ggtcagctcg gcgagagagg gaagaaaagt cagactctta gtcaagaatt agacgaggct
     9481 ggatttgtta gttatttagg ggataaggag aattggtgga taggtctatc caaggaaaaa
     9541 caaggttcct tcaccattcc ctactatgtc ttgggtcaag cctggcagat tttcatttct
     9601 gaccaacccc tagatggttt agtcgttaca ccttttgaag ctccttatca agaacatttt
     9661 gaacgctgga agctgaatgc tgagaaaacc ctcttttacg gttctgtaaa tctgcagcag
     9721 tctgagagtc tctttgccta ttacgaaccg atttataggg ttatcattca gggaaatctc
     9781 aatcaaatcg tagaagagtt aaatctcttg gagaaggtag ttcttgaaaa tacgccgcga
     9841 attccgatta ctaaacagct ttttatccag tttgtcatgg atgtcttcca tttatttgaa
     9901 catctcaaag ctgatgatat gacggacatt gtcaaaacca ttcatgctat tcaatccttc
     9961 gatgaattgg tttcttatat caaggaaact ctgatcagct ttttcggtca ataccgtatg
    10021 aatgaaaatg tggtcagtgt gctggaagtc attggtcgtg attaccaaaa agagctttcc
    10081 ctcaaggata tcagtaaggc cctctttatc aatcctgtct atctagggca gttgattaag
    10141 cgtgaaaccg attcgacctt tgcagagtta ctaaacaaac aacgtattaa ggctgcccag
    10201 cagctcttgc tttcaaccag tgacagtatc gaagatattt gttatgctgt tggttacagt
    10261 aaccttggat atttctataa agttttccga aaattgtgcg gaaaatcgcc aaaagcctac
    10321 cgaaaacagg tagaaactat actataagat ttgtattcct ttacaaaatg tgctataata
    10381 ttatcaggag gttctatcat gaaaaagaaa ccaatttatc tatgggtctt gctaatcttg
    10441 tctgccctta tttcagttcc gtctctgttt ggaattgtga gtcccttgcc tagtaaagaa
    10501 gcccttcgtg ttgctcagaa acaagttgca ggggtcaatg ctcagcaatt agaagaccag
    10561 cttaattata cctatagagt agcagaagca tctcattcta tttttaatgt tgctttgatt
    10621 gtgctatcta ctattttagt ggtcgtagcg attgtcttcc ttgttcgtaa aaatttgcaa
    10681 tatgcaaact atacttacgt tggctatgtt ttgttagcta ttattggttc gatttatggc
    10741 tatgttggtt tacaagacgc tgtgcagttg gttcaagatg agagcatgcg tttgacagtg
    10801 agtattggtt caaaagctgt tagcattttc tatatcgtca tcaatgttct cttcctagcc
    10861 cttgtcttct ataagatgtg gcgacaacag aaagccttgg cagaagaaga ggaaacagaa
    10921 gagcttgcct aagtattgac aaaaaagaac tatcaagata caatcttggt agttattttt
    10981 tgattataga taaaatcatg gaggtacata tgaagacaat ttctttagtt tatattagtt
    11041 tgagtggcaa cactgaaagt tttgtgacgc gcttgaaaga ctatctcttg tcccagtaca
    11101 aagggattga ggttcaaaag attcatatca aggatttggt caaggaaggc aaaaatttct
    11161 atgaaatgga ccatctctat gtcgcttttt tgccgaccta tctcgaaggt gggaatggcg
    11221 tggataacgg agatgttgag attttgacaa caccggtggg agattttatt gcctatggta
    11281 acaatgctag taagtgtttt ggtgtggttg ggtcaggaaa tcgtaacttt aataaccaat
    11341 actgcctaac agccaagcaa tacagtcaac gctttggctt ccctgtattg gctgactttg
    11401 aaatgcgagg catgctggaa gatatcaaac atgtcgcagc tattatcgca gatttgtatg
    11461 agttggaaaa ggagaattaa tactcaatga aaatcaaaga gcaaactagg aagctagtcg
    11521 caggttgctc aaagcacagc tttgaggttg cagatagagc tgacgtggtt tgaagagatt
    11581 ctcgaatagt ataaagttct tataagaggt ggttgaagtt gttcaactgt tttttgagta
    11641 taaacagtct ttaagaacgt aaaaaagcat aagttcaggt cttcaaaacc ttgttcttat
    11701 gctttttatc atagaaatat ttgctgaatt ttctcttgaa atgaaacctt atcttcatct
    11761 cgcgcttgtc ccttaccctg cttttccgat tgcgagtgcg tagataaaga agatggcgaa
    11821 gccaaagagg aaaatcaatc ccgcaatggc aaggtgtttg agccaagaag gaagattttt
    11881 gttttcacgc gttaccaagg cgtaattcaa aagagcaaag aaaggtgttg tcaggaaaga
    11941 tccaatcatg gcaaagcgga gcatggttga aacctgacca gcgaagaact tgataatgac
    12001 gataccgatg atagcagtga tggtcatcca gatgttcaaa gatttacgat tgtcctcttt
    12061 ttgactgatt agcagtcgga gagattcctg attaacgcga gaatagccat cgataacagt
    12121 tataactgtt ccaaagatac agaggaaggc aataaaggta atcaagtaac gggaccattc
    12181 gccaagaaca gaggcataca tgcccacgaa ttgagagatg tatttggctg aagcagcttc
    12241 aaccgcctgc cctgtaggat actgaatcag tgctcccagt gccacaaaga agacggctag
    12301 gatagctgtt ccaatataac cagtgttaaa gtcaaacaga gcgtcttctg tgttaaagtt
    12361 gacggtcttt ctcttttcag ctgaccaaag tgaattgata gctgaaattt caataggagc
    12421 cggcatccat cctaggaggg agacgatgaa gggcagagct gccatttgcc aaggtgtctt
    12481 ctcgacaaaa tcagaactgt attctggatg cttgaccgct gctatgataa ctgccagaac
    12541 agtcgcaatg gttaaggcag acataatcca tttgaccatg ccgtctaaaa gtttgtagcc
    12601 tccaaagagt agcatagccc aaatgattgc aacgagaatg agggaccact gagtaatgct
    12661 aagtccaatc attgggaagg cactggcgat gatagctgag cacagaatgg caacaccagc
    12721 cgtgttgacc atagccgaaa agacattgag gataaagaaa atccagagat agagttttcc
    12781 tttttcggca taaccttcaa ccaaagtctt tccagtatca gctgtgtatt cagcaccaaa
    12841 acggaaaaat ggatatttaa agacattggc taagatgact aagagaagta gagaccaacc
    12901 gtaagaaccg ccagcttgag ttgaggatac aatgtgggaa cctccaacag cggcagttgc
    12961 cattaggatt ccaggtccca ttgcttttag cttgcttgcc caggttgatt gatttaagga
    13021 aatagcttgc gacatgataa atactccttt ttgaattttc agaataatct gtatatgtaa
    13081 tctatattct acaaaaaatt ttggaaaaat gcaagaatat tttgaaaaaa gatagaaaat
    13141 ttacaaagaa aatctgaaat aactgttatg atatag
//
LOCUS       DAVBNZ010000055        13159 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000055 DAVBNZ010000000
VERSION     DAVBNZ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.055"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..367
                     /locus_tag="VQ860_001724"
     CDS             <1..367
                     /locus_tag="VQ860_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3120115.1"
                     /translation="PNLEQVQTMLEQTFTEKHYENTILHSDQGWQYQHDSYHQFLESK
                     GIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSRKQLEQAIVDYIDYYNNKR
                     IKVKLKGLSLVQYRTKSFG"
     gene            complement(442..972)
                     /locus_tag="VQ860_001725"
     CDS             complement(442..972)
                     /locus_tag="VQ860_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HET3120116.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKIEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAYMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSDIHKLGI"
     gene            complement(966..1434)
                     /locus_tag="VQ860_001726"
                     /pseudo
     CDS             complement(966..1434)
                     /locus_tag="VQ860_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1984..2661
                     /locus_tag="VQ860_001727"
     CDS             1984..2661
                     /locus_tag="VQ860_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET3120117.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGKIESAIA
                     GEVVEGPYQSAVKNVEAHGLEEKIQVRLANGLAAFEEEDRVSVITIAGMGGRLIARIL
                     EEGLDKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2648..3445
                     /locus_tag="VQ860_001728"
     CDS             2648..3445
                     /locus_tag="VQ860_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET3120118.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3462..4565
                     /locus_tag="VQ860_001729"
     CDS             3462..4565
                     /locus_tag="VQ860_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET3120119.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            4866..5885
                     /gene="galE"
                     /locus_tag="VQ860_001730"
     CDS             4866..5885
                     /gene="galE"
                     /locus_tag="VQ860_001730"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3120120.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            5887..6840
                     /locus_tag="VQ860_001731"
     CDS             5887..6840
                     /locus_tag="VQ860_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3120121.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(6902..7108)
                     /locus_tag="VQ860_001732"
     CDS             complement(6902..7108)
                     /locus_tag="VQ860_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET3120122.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            7160..7636
                     /locus_tag="VQ860_001733"
     CDS             7160..7636
                     /locus_tag="VQ860_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET3120123.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            7645..8316
                     /locus_tag="VQ860_001734"
     CDS             7645..8316
                     /locus_tag="VQ860_001734"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET3120124.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8447..8785
                     /locus_tag="VQ860_001735"
     CDS             8447..8785
                     /locus_tag="VQ860_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET3120125.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            8788..9417
                     /locus_tag="VQ860_001736"
     CDS             8788..9417
                     /locus_tag="VQ860_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET3120126.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            9657..10808
                     /locus_tag="VQ860_001737"
     CDS             9657..10808
                     /locus_tag="VQ860_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3120127.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLSIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            11126..11875
                     /gene="truA"
                     /locus_tag="VQ860_001738"
     CDS             11126..11875
                     /gene="truA"
                     /locus_tag="VQ860_001738"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET3120128.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            11865..12638
                     /locus_tag="VQ860_001739"
     CDS             11865..12638
                     /locus_tag="VQ860_001739"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3120129.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKVFVYRAIAQADQYGVRQYEANKNN"
     gene            12616..13077
                     /locus_tag="VQ860_001740"
     CDS             12616..13077
                     /locus_tag="VQ860_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3120130.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMAGMIVGFILSQSIKKIK"
BASE COUNT         3762 a         2466 c         2903 g         4028 t
ORIGIN      
        1 acccaactta gaacaagtac aaacaatgtt ggaacagaca ttcacagaga agcactacga
       61 gaatacgatt ctccatagtg accaaggctg gcaataccaa cacgattctt atcatcagtt
      121 cctagagagt aagggaattc aagcatccat gtcacgtaag ggcaacagcc cagacaacgg
      181 tatgatggag tccttctttg ggattctgaa atcggaaatg ttttacggtt atgagaagtc
      241 gtttcagtcg cgtaagcaat tggaacaagc tattgtagac tatattgatt actacaacaa
      301 taaacgaatt aaggtaaaac taaaaggact tagccttgtg caatacagaa ctaaatcctt
      361 cggataaatt aattgtctaa ctttttgggg ggcagtacat ttttggtata tataaaattt
      421 gtaggagcta tatctacaat tttatattcc cagtttatgg atgtcgctta ctatgttcac
      481 aatgttatcc agtgtttttt ctctaatatt taaggagtgt tctgtttctc gaataaattc
      541 ttcaaagttt aacccgtcaa cttgttcctg aacaagaaaa taatcatcca cgatataaaa
      601 ttcatcagtt aaattagtag tataactttt atcggctaat ttttttagca tgtaagcctc
      661 attttttata tcatcaagtg ctgtccattc tccttcggca tcataattca caaaaggtct
      721 tgactgcttg atgattactt tttgcccgtc cgattttcta attgcccgat aaacattccc
      781 tttatttgat ctcttaataa ttttttctat tttgtattta tttattgcag agtccttact
      841 tgaaacttca catgtggttt gaaaataaat ccttttttct tcttctgaaa ataaatccat
      901 tttccagcta ggaagactag ggaaattttg tctcttatct tctacatagt tcttcctttt
      961 ttcatctagc aataaataga tgactttttt atttttttca tcataagctt gtttttttaa
     1021 aaaagcccca tatctataat gaactggaga atgcattcca cattgatagt cagatagtat
     1081 ttttggagcc ttaaattctg acagtctatt cgtaagatta caaatcatac tcttagcttc
     1141 agattctgac ttaggatata gagttataaa tttgttagca gtagggctca tttccctagg
     1201 ggaattaatt ctttttaatt cctctaaatt tttaacaact ttaaagctac aattatttag
     1261 ttgggatagt ttatacacaa tcttaaaaat atttacagcg tcttttattt gggagcttat
     1321 gtgtattttc cacccttgtg caggcacctt atctgataaa taatagtaat tccaaatatc
     1381 accctgttgg aaatttttat cacattttaa acattctttc tctaataaat ccataacaaa
     1441 ctcctaatta ttaaaatagg ctagagacac agcactagcc tattccgtaa gtaaagctac
     1501 ttattttata taaaatataa ctagcgacct gtaattaaac aagtaaaaga acaatactta
     1561 gggagacctg tgacaatgat atcttcctct ggaagtagtt ctaattcaaa caatgtttgt
     1621 tccatgactg tatcctcctg ttatgataaa ttccagaaag catagagcaa attcgtggtt
     1681 cgtctgacta aatttcttat ctgaacacca ccttcaaata caaattttag tcaaactttt
     1741 attttttcta actttctaat tatattctac catgtgtttt tatatgtcaa gaattttctg
     1801 aataaactgt ttatttttta tttttttgac atttttgcaa attgtttaaa atctttcaat
     1861 tggattcact tattacttta ggacattgaa gcttctttcg ccagaggtgc ttatattact
     1921 gggaagttga agattgaaat gtggtataat aagaggtaat agagttttgg aaagagagag
     1981 aagatgattt caaagagatt agagttggta gcttcctttg tgccgcaggg agccatttta
     2041 ctagatgtgg ggagtgacca tgcttatttg cctatagagt tagtcgaaag aggaaaaatc
     2101 gaaagtgcca ttgcaggtga agttgtggag ggaccttatc agtctgctgt caaaaatgtt
     2161 gaggcccacg gcttggaaga aaaaatccaa gtccgtttag ccaatggttt ggcagctttt
     2221 gaagaggaag accgagtgtc tgtcattacc atcgcaggga tgggcggccg tttgattgct
     2281 aggattttag aagaaggctt ggacaagtta gctaacgtag agcgtttgat tctccagccc
     2341 aataatcgtg aagacgactt gcgtatctgg ctacaggatc atggattcca gattgtagca
     2401 gaaagcatct tagaagaagc tggaaagttt tatgagattt tggtggtgga agcaggacaa
     2461 atgaagctat cagccagtga tgttcgcttt ggtcccttct tgtccaaaga agtcagtcca
     2521 gtatttgtcc aaaaatggca aaaagaagct gagaagctag agttcgccct cggacaaatc
     2581 ccagaaaaaa atctggaaga acgtcaagtt ctagtagata agattcaagc tatcaaggag
     2641 gtgctccatg ttagcaagtg aagtgatcca agcttatgaa gccttttgcc ctcaggaatt
     2701 ttctatggag ggagacagcc gtggtctgca aattggcact ttagacaagg gtatccaaag
     2761 ggtcatggtt gccctcgata ttcgtgaaga gacagtggca gaggccattg aaaagggtgt
     2821 ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct atcaaggact tgcttgccag
     2881 ccgtccgcaa aatcagattt acatcgacct gattaagcat gacatcgcag tttatgtcag
     2941 ccataccaat attgatatcg ttgaaaatgg gctcaatgac tggttttgtc agatgctagg
     3001 aatcgaggag acgacttatc tgcaggaaac aggtccagaa cgtggaattg gacgtattgg
     3061 gaatattcag cctcagacat tttgggaatt ggcccaacag gtcaagcaag tctttgacct
     3121 agatagcctt cgaatggtgc attatcaaga gaatgatttg cagaagccta tttcaagagt
     3181 agcaatttgt ggtggaagcg ggcagtcttt ctataaggat gctttggcaa agggggcaga
     3241 tgtctatatc actggtgata tctactacca tactgctcag gatatgctgt ctgatggctt
     3301 gttagcattg gatccaggtc actatatcga agtgcttttt gtggaaaaaa tcgcagcact
     3361 ccttactcaa tggaaagaga aaaaaggctg ggaactagag attttaccta gtcaagcatc
     3421 gaccaatcct ttccgtcata tctagttaga aagtgaagac aatgaaaaaa gttgccatta
     3481 ttggagcagg aattgtggga gcaacagctg cctactacct ctcgagagaa agtgacctag
     3541 aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa ggccgcagca ggaattatca
     3601 gtccttggtt ttccaaacgc cgtaataaag cctggtacaa gatggcgcgc ttgggggctg
     3661 acttttatgt ggatttatta gctgatttag agaaatcagg acaaaaaatc gacttttacc
     3721 agcgttcggg agtctttctc ttgaaaaagg atgaatccaa gttggaagaa ctttatcaac
     3781 tggccctcca gcgcagagaa gaatctccct tgatagggca attagccatt ctggaccaag
     3841 cttcagctaa tgaattattc cctggtttgc agggatttga ccgcctgctc tatgcttctg
     3901 gtggagcgag agtagatggc caactcttgg taactcgtct gctagaagcc agtcatgtca
     3961 agctggtcaa agaaaaagtg actctgacac tcttatcatc aggctaccag attggcgaag
     4021 aggtgtttga tcaggttatt ttggcaacgg gagcttggtt gggggacatg ttagagcctt
     4081 taggttatga agtggatgtc cgtcctcaaa aaggacaact acgagattat cagcttgccc
     4141 aagacatgga agattaccct gttgtcatgc cagaagggga gtgggatttg attccctttg
     4201 caggtgggaa attatccttg ggcgctaccc atgaaaatga catgggattt gatttgacgg
     4261 tagatgaacc cttgctccaa caaatggagg aggcggcctt gcctcattac ccagttttag
     4321 ctagagcgac ttcaagggct gagcgtgtgg gaatccgtgc ctataccagt gatttctctc
     4381 ccttctttgg gcaggtgcca gaattggcag gtgtctatgt agccagtgga ctaggttcat
     4441 caggcctcac aactggtcct atcattggtt accatctagc ccaactgatc caagacaagg
     4501 agttgacctt ggaccctcta aattacccaa ttgaaaacta tgtcaaacga gtaaaaagcg
     4561 aataatactc aatgaaaatc aaagaacaaa ctaggaaact agccgcgggt tactcaaagc
     4621 actgctttga ggttgtgtat agaactgacg aagtcagctc aaaacactgt tttgaggttg
     4681 tgtatagaac tgacgaagtc agtaaccata cccatggcaa ggcgacgttg acgtggtttg
     4741 aattggattt tcgaagagta taagcatttt actgaaattt tatcaggtag tttaggatgg
     4801 caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa ataatctgag aatcgaggaa
     4861 aaaagatgca agaaaagatt ttggtaactg gtggtgccgg ttttattgga acccacactg
     4921 ttattgaatt gatccaagca ggccatcaag ttgttgtggt ggataatctt gtcaatagca
     4981 atcgtaagag tttagaagtt gttgaaagaa tcacaggagt tgagattcct ttctatgagg
     5041 cagatattcg tgacacagtt accctcagag atattttcaa gcaggaagaa ccgactggtg
     5101 tcattcactt tgctggtttg aaggctgttg gcgaatcaac acgtatccct cttgcctact
     5161 atgacaacaa tatcgctgga actgtcagcc ttttgaaagc catggaagaa aacaactgta
     5221 aaaacatcat cttcagttct tctgcgacag tttacgggga tccgcacaca gtgcccatct
     5281 tggaagattt cccactttca gtgaccaacc catacggtcg taccaagctc atgctagagg
     5341 aaattttgac cgatatttac aaagcagact cagaatggaa tgttgtcttg cttcgttact
     5401 ttaacccaat cggagcccat gagagtggtg atttgggaga aaatccaaac ggtattccaa
     5461 acaatctctt gccatatgtg actcaagtag ccgttggaaa attagagcaa gtgcaagtgt
     5521 ttggagacga ttacgatacg gaagatggaa caggtgttcg tgactatatc cacgttgtcg
     5581 atttggctaa gggtcacgtt gcagctttga aaaaaatcca aaaaggttca ggactaaacg
     5641 tttataacct tggaactggt aaaggttact cagttcttga aattatccaa aacatggaaa
     5701 aagcggtggg acgtcctatt ccttaccgca tcgtagaacg tcgcccaggt gatatcgctg
     5761 cctgctactc agacccagca aaagctaaag cagaactcgg ttgggaagca gaactcgaca
     5821 tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa gcatccaaat ggatttgaag
     5881 actaagatga tgatttcaat catcgtccct tgtttaaacg aagaggaagt acttcctctt
     5941 ttttatcagg ctctggaagc tttacttcca gatttggaaa cagaaatcga gtatgtcttt
     6001 gtcgatgatg gatcaagtga tgggaccttg gaactcttaa aggcctatcg ggagcaaaat
     6061 ccggcagtcc attatatttc tttctctcga aattttggca aagaagcagc cctttatgca
     6121 ggcttgcaat atgcgacagg agatttggtg gtggtgatgg atgcagacct ccaagatcct
     6181 cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa atgtagactt ggactgcgtt
     6241 gggacacgga gaactagtcg ggagggagaa cccttctttc gcagtttctg tgctgttctc
     6301 ttttatcgcc tcatgcaaaa aatcagccca gtagctctgc cgtcgggtgt ccgtgatttt
     6361 cgtatgatga gaaggtctgt ggtcgatgcc attttaagct tgactgagtc caatcgtttt
     6421 tctaagggac tctttgcctg ggtcggcttt aaaacccact atctggacta tccaaatgtc
     6481 gaaaggcagg ctggcaagac cagttggagt tttaggcaac tcttttttta ctccattgaa
     6541 gggattgtta atttttcaga tttccctttg actatagcct ttgtagctgg tctcctatct
     6601 tgttttcttt ctctgctgat gacctttttt gttgtggttc ggaccctcat tttgggcaat
     6661 ccgacatctg gttggacctc tctgatggct gttattctct ttcttggagg cattcaactc
     6721 ttgaccattg ggattctcgg taagtatatc agtaagattt atttagagac taaaaaaaga
     6781 ccactttatc ttatcaaaga aaaaagtgac cttcctgatt ttacagaaaa aataaagtga
     6841 aaagactata attttacatg gaaatgtgct aaactagagg gagtggatta tcgccattga
     6901 tttaggcttc ctggtttcca atcagggcgc gagttgggca atttttaaca gcctctaaga
     6961 catcctgact aggagaaatt tctttttcca gttggtcagg gtcatcgtaa aaacgcacga
     7021 ttccattatc gtggtaatca aataaatcag aataagtttg gcaaagtcca caggcgatac
     7081 atcgttcagg tataagtgtg attttcatgt tcatatttat attgtaataa gaaaagtaaa
     7141 aaaaaacaag gagtaaggta tggcaaaaga accgtggcaa gaagatattt atgatcaaga
     7201 agaatcaaga gcagggcgtc ggcatcgaaa ccacggaggg gctgatagga tggctaatcg
     7261 tattttgacg atcctagcta gtattttctt tgtaattgtg gtggtgatgg tcatcgttct
     7321 catctatcta tcatcggggg ggagtaatcg cacagcagcc ttaaaagact ttcatgattc
     7381 tgatgcaagt gtagtacaaa tctcatcttc aagcagttct cagcctgagc agagttcaga
     7441 gccagaatct acttctagta gttcagaaga agctgctaat cctgaaggaa cgattaaagt
     7501 tctcgcagga gaaggggaag cagctattgc cgctcgtgca ggaatctcca ttgctcagtt
     7561 agaggccttg aatcctgggc acatggctac aggatcttgg tttgctaatc caggtgatgt
     7621 tataaaaata aaataggagc cgatatgaaa acaattcaaa ttgctattga tggtcctgct
     7681 tccagcggta agagtacggt cgcaaagatt attgctaagg attttggatt cacctacctt
     7741 gatacaggag ctatgtatcg tgcagcgacc tatatggctc ttaagaacca attaggagtt
     7801 gaagaagtcg aagcccttct agccttgttg gaccagcatc caatcagctt tggacgttca
     7861 gaaactggag accagcttgt ttttgtagga gatgtggata ttacccatcc tatccgtgaa
     7921 aatgaagtga ccaatcatgt ttctgctatt gcagcaattc ctgaagtgcg tgagaaactg
     7981 gtttctctcc aacaagaaat tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt
     8041 ggaactgttg tattgccaca agcagaattg aaaattttcc tagtagcttc tgttgatgag
     8101 agagcagagc gtcgttacaa ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc
     8161 ctaaaaaagg aaattgctgc gcgtgactac aaggatagtc atcgtgagac ttctcctctc
     8221 aaacaagcag aggatgctgt ctaccttgat acaactggtt tgaacattca agaagtagtt
     8281 gaaaaaatca aagcagaagc tgaaaaaaga atgtaaatgt agaaaagccg atagattgat
     8341 atcggttttt ttctaaattt gtcaaaatgc tgattttagg gtataatagt tgctgttcga
     8401 gaaattttga ttttcaaaga atagtgaatg atgataagga gaaaccatga acaatttacc
     8461 aaattgtccc aaatgtaact cagagtatgt ctacgaagac ggtgccctac tggtttgccc
     8521 agagtgtgct catgagtgga atcctgctga agttgcagaa gtagaagaag gtcttgtcgc
     8581 tatcgatgcc aacggaaata aattgactga tggtgataca gtaactctca tcaaggactt
     8641 gaaagtaaaa ggtgcgccaa aagatttgaa acaagggacg cgcgtgaaaa atatccgcat
     8701 cgtagaaggc gaccacaata tcgactgtaa gattgatggt tttggtgcca tgaaacttaa
     8761 atcagagttt gtgaggaaga tttaagcatg tcaaaacact ataaacttgt attttatagc
     8821 cgtatcttct tgtttctagc ggcttttacg ggagtttatc ttgaaattac taggcatggt
     8881 ggttttggga tgcttctcta ttacacggtt ctgtccaacc tcttggtaac tatttttacc
     8941 ctttatcttc taaaggttat gagccgtgta ggtgaaaatt ggcaaaggcc aagtctcttg
     9001 cgcttaaaag gtggggtcac catgagcatc atgattacct gtgtgattta ccatttcctc
     9061 ttggcgccca ttgcgactaa tttctatacc ctagaaaatt tcctttgcca ctatatcgtt
     9121 cccatctggt ttttagcgga taccctcttt tttgacaaac agggtcaata caagatttgg
     9181 gatccagcag tgtggaccat tttacccttt ctgtatatga tgtttgctct ttttaatggc
     9241 ttggttctaa aactcaatat tccaaatgcc aaggataatc ctttccctta cttctttttg
     9301 aatgtgaaca agggttggaa tgttgtgttt aagtggtgtc tgattatctt tgttgcctat
     9361 atggtagcag gatttatttt ctactttatc aagcaaatca agagaaagtc atcctaatac
     9421 tcttcgaaaa tctcttcaaa ccacgtcagt ttccatctgc aacctcaaaa cactgttttg
     9481 aacaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaag
     9541 ggattcattt tcgaatttaa gaaggagtct acaaaccaat gaggcttctt cttttcttgc
     9601 ttatttgata actatcaaaa aagtagaaga ttaagagaaa tatagaaaga gatttcatga
     9661 aacaattttt agaacgggcc agcattttgg ctctctccct cgttttgatt acctcctttt
     9721 ccatttcgag tgccctacca gccatgtttg actattatca gggttattct aaggaacaaa
     9781 ttgagctctt ggtgagcttg ccttcctttg gaattatgat gatgttactg ctaaatggtt
     9841 tcttagaaaa aatatttcct gagcgcttac agattagttt gggcttgctg attttatcat
     9901 tgagcggtac agctcccttc tggtaccaag cctatccctt tgtctttgga acacggcttc
     9961 tctttggttt gggtcttggg atgatcaatg ccaaggccat ttctattatc agtgaacgct
    10021 accaaggaaa aaggcgaatt cagatgttag ggctacgcgc ttctgcagag gtcgttggag
    10081 cttctctcat taccttggcc gtcggtcagt tgttggcctt tggttggaca gctatctttc
    10141 tagcctatag tgctggattt ttggtgctgc ccctttatct gctctttgtc ccttatggaa
    10201 aatcaaagaa agaagtcaag aaaagagcga aggaagcaag tcgtttaact cgagaaatga
    10261 aaggcttgat ttttacctta tctatcgaag cggcagttgt agtttgtacc aatacagcta
    10321 ttaccatccg tattccaagt ttgatggtgg aaagaggatt gggggatgcc cagttatcta
    10381 gttttgttct tagtatcatg cagttgatcg ggattgtggc tggggtgagt ttttctttct
    10441 tgatttctat ctttaaagag aaactgctcc tctggtctgg tattaccttt ggcttggggc
    10501 aaattgtgat tgccttgtct tcatccttgt gggtggtagt agcaggaagt gttctggctg
    10561 gatttgccta tagtgtagtc ttgacgacgg tctttcaact tgtctctgaa cgaattccag
    10621 ctaaactcct caatcaagca acttcatttg ctgtattagg ctgtagtttc ggagccttta
    10681 cgaccccatt tgttctaggt gcaattggct tactaactca caatgggatg ttggtcttta
    10741 gtatcttagg aggttggttg attgtaatct ctatctttgt catgtaccta cttcagaaga
    10801 gagcttagga ttgattccta agtttttctt ttgatactca atgaaaatca aagagcaaac
    10861 tatagttgat tgagtttgga atagtacgct gtagctgcta aaatatttct agaaattaat
    10921 ttgactttcc taatagagtt attcatatct tatttcaatc tactatagaa agctagccgc
    10981 aggttgctca aaatagtgtt ttgaggttgc agatggaaac tgacgtggtt tgaagagatt
    11041 ttcgaagagt atgagatttt tatacccata caatatttgt tttaggtcct tgtttacaga
    11101 ctaatttctt gataaaatag aggttatgac gagatataaa gcaactattt cctatgatgg
    11161 ttatgccttt gctggctttc agcgccagtc tcatgcgcgt agcgttcagg aagaaattga
    11221 aaaaaccttg accagattaa ataaagggca agccattact gttcacggtg ctggtaggac
    11281 agatagtggg gttcatgccc tgggacaggt cattcatttt gacctgcctt atcagattga
    11341 tgaggagaaa ctccgttttg ccttggatac ccagtctcct gaagatattg atgtgatttc
    11401 gattgagctt gtggcagatg attttcattg ccgttatgcc aagcatagca agacctatga
    11461 gtttattgtg gatagaggac gtcccaaaaa tccgatgcgc cgtcactatg ccacccactt
    11521 tccctaccca ctcgatgtgg aacgaatgca gattgcaatc aaaaagctag agggaaccca
    11581 tgattttacc ggttttacag cctctgggac tagtgtagag gataaggttc gcaccatcac
    11641 agaagctagt ttaatagtcg atgagacagg acaatttttg acctttacct tttccggaaa
    11701 tggtttcttg tataaacaga ttcgcaatat ggtggggact cttctcaaaa tcggtaacaa
    11761 ccgcatgcca gtagagcaga ttgctctcat cttggagaag aaggacaggc aacttgcagg
    11821 tcccactgca gcaccaaatg gtttgtattt aaaggagatt cgttatgaag aataatcgta
    11881 ttttagcact ttctggaaat gatattttta gtggtggtgg actgtcagct gatttggcta
    11941 cctatacctt gaacggcttg catgggtttg tagcagtgac ttgtttgaca gccttgacag
    12001 aaaaaggatt tgaagtcttt ccaactgatg ataccatttt tcaacatgaa ttagatagct
    12061 tgcgtgatgt ggaatttggg ggaattaaga ttggtcttct ccctactgtc agtgtggctg
    12121 agaaggcctt ggactttatc aaacaacgcc caggagtacc tgtggtgttg gatcctgtct
    12181 tggtctgcaa ggaaacgcat gatgtagctg tcagtgagct ctgccaagag ttgattcgct
    12241 ttttccctta tgtcagtgtg attacgccta atctcccaga agcagaatta ttatccggtc
    12301 aggaaattaa aaccttggaa gacatgaaaa ctgcagcgca gaaattgcat gatttaggag
    12361 ctccagcagt cattatcaag ggaggcaatc gtcttagtca ggacaaggct gtggatgtct
    12421 tttatgatgg acagaccttt actatcctag aaaatccagt tatccaaggc caaaatgctg
    12481 gtgcaggttg tacctttgcc tctagcattg ccagtcactt ggttaaaggt gataaacttt
    12541 tgccagcagt agaaagttct aaggttttcg tttatcgtgc tattgcacaa gcagatcagt
    12601 atggagtaag acaatatgaa gcaaacaaaa acaactaaaa tcgcccttgt atccctatta
    12661 accgcccttt ctgtggttct aggttatttc ttaaaaatcc caacacctac aggaattcta
    12721 actcttttag atgctggtgt cttctttgcg gccttttact ttggtagtcg tgaaggagcg
    12781 gtagtcggag gactagcaag tttcttgctt gacctcttat caggctaccc tcagtggatg
    12841 ttttttagct tggtcaacca tggcttgcag ggatttttcg caggatttaa aggaaaaagt
    12901 cagtggttag gccttatttt agcaactatt gccatggtag ggggctacgc cttgggttct
    12961 actttgatga atggctgggc agcagccctc ccagaaattc taccaaattt tatgcaaaat
    13021 atggcaggga tgattgtagg atttattctt agtcaaagta tcaagaagat taagtaatac
    13081 tcttcgaaaa tctcttcaaa ccacgtcggc ttccatctgc aacctcaaaa cactgttttg
    13141 agcagcctgc ggctagctt
//
LOCUS       DAVBNZ010000056        13139 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000056 DAVBNZ010000000
VERSION     DAVBNZ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13139
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.056"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(278..1501)
                     /locus_tag="VQ860_001741"
     CDS             complement(278..1501)
                     /locus_tag="VQ860_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3120131.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1669..2991
                     /locus_tag="VQ860_001742"
     CDS             1669..2991
                     /locus_tag="VQ860_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3120132.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGGIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTIENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            2993..4879
                     /locus_tag="VQ860_001743"
     CDS             2993..4879
                     /locus_tag="VQ860_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET3120133.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            5047..5391
                     /locus_tag="VQ860_001744"
     CDS             5047..5391
                     /locus_tag="VQ860_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3120134.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5401..6813
                     /gene="lacG"
                     /locus_tag="VQ860_001745"
     CDS             5401..6813
                     /gene="lacG"
                     /locus_tag="VQ860_001745"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3120135.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVREFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6883..8562
                     /locus_tag="VQ860_001746"
     CDS             6883..8562
                     /locus_tag="VQ860_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3120136.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPCEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(8688..10127)
                     /locus_tag="VQ860_001747"
     CDS             complement(8688..10127)
                     /locus_tag="VQ860_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3120137.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(10131..11480)
                     /gene="trkA"
                     /locus_tag="VQ860_001748"
     CDS             complement(10131..11480)
                     /gene="trkA"
                     /locus_tag="VQ860_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET3120138.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVNRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11668..12516
                     /locus_tag="VQ860_001749"
     CDS             11668..12516
                     /locus_tag="VQ860_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET3120139.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12531..13079
                     /locus_tag="VQ860_001750"
     CDS             12531..13079
                     /locus_tag="VQ860_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET3120140.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         4025 a         2106 c         2804 g         4204 t
ORIGIN      
        1 gagaattgta aaaacaaaaa tggggatttc atataaagtt tattctagga gtatgtatct
       61 tgaataaaaa ttgttattta agttctgggg gttatgatga atgtttttat aataataaaa
      121 tgcagctaga agaaaagtta ttttaatata aatcactcaa catagagaga aggcggtttc
      181 ctatatggaa gtcgtcttgt tttcatattg tctaaatacg agatatttac tacaggttat
      241 agttgattta aacaggtcta tagatttcta atatatatta aggtgaaata atatcttgta
      301 atacattgct atgctctatg aaaaaagcaa cgatagctaa tgcacaagct cctatacttc
      361 cacgatgttt gttgtaaggt aaaatttcaa tttctatatt acgagtaaag ggaacgaagt
      421 ggagctggtc ttggatttta tccctgactt catgagtgaa aggttgataa ttaagcaatt
      481 gactgttgat atagatttta tcagcaggat tgatgaggag aagatttgca atagaagtgg
      541 ctaataaatt gactccttta tcaatttgtt gacgtaaagc ggagtcgcct aaattataag
      601 ccgttaaaag ggtgtctaaa tgaatgtctt tttcagtctt tacaaggctt tttagtacag
      661 ttagttggga atttttaaat aataattggg cgtgtttgat taaccaagca tccgaaatat
      721 atgtttgtaa acaacctttt tttccgcatt cacaatattg cccattcaat tcgacaatgg
      781 tgtgtccaat ttctccgata taaggatttt tagaggctcc tattttttct tttgtgaaaa
      841 aggaagtgta aatacctaat ccagcgtgta ggaaaataaa gttatcgggg gtattgtgtg
      901 gattaaaaag gtattgtcct atagccatac aatcgatatt attttttaca ataaaaggaa
      961 aattgaatct tttaattaca tttaataaat taaaagattc ccatatgggg ttgtttgtaa
     1021 tgatacttcc ggagtctttg ttataatgtc caggtattga taagccaaat ccaagtaatt
     1081 ttgtttccaa agggacgtac tctatagctg tttttatcat attggtaatg gtggaattga
     1141 tttctgaaat aggataatct tcattcaaaa tttctgtctc gaaaagagtt ttcccttgta
     1201 agtcacatag actgagaaag atacctagga cgtttatttc aatacctcca acaacatacg
     1261 gaatattatc tgtgatagaa atagtttttc tacgtcttcc agatccggaa aactcgctaa
     1321 attcatcacc agtttcgtat atgagggact gttcgcttag ctcttttatg atgttagtcg
     1381 ttgttgctgg agtaagtcct gtttcattaa caatatctgt acgggatgtt gctggatttc
     1441 gatatagaaa ctccagtata gtggctctat tttgtaaaaa ggctgattgt tttgtaatca
     1501 tttgtttcct cctttggttt attttatatt aaacataaga aaaaatcaat taaaattatt
     1561 attctataca aagaaaaaaa tattgtaaaa acaacaaaaa atatattgac aacgctttct
     1621 gttagtggta tatttaattt ataaaaaata aaaaaaggag ttccggtgat gaacaatatt
     1681 ttagcgtttt tagaaacaaa agtcgctccg tttggtgaaa aagttggcaa ccaacggcat
     1741 ttgaaagcta ttcgtgaagg atttatgatg gcaatgcctt tgattttagt cggatcttta
     1801 tttcttattc taatcagttg gcctcaagag gattttacaa attggctgaa tagtgttgga
     1861 ttgctaagta tcttgacaac tatgaatcag tcaacagtag cgattatctc cttggtcgct
     1921 tgtttcggta ttgcctacag gttgtcggaa ggatatggta cagatggtcc gtcggcaggg
     1981 atcatagcct tatccagttt tgtattgatg gcacctcgtt tttcgagtat ggtttatgat
     2041 aaaaatgggg agcaggtcaa gcagttattt ggcggcgcaa taccattttc tagcctgaat
     2101 gcatcttctt tgtttatggc gattactatt ggattggtta cagcagagat ttatcgtatg
     2161 tttatccagc gcggaattac gataaaaatg ccaagtggtg tcccagatgt ggtaagtaaa
     2221 tcattttcag ctcttttacc tggctttact acttttgttt tgtgggctct ggtcttaaaa
     2281 ggtcttgaag cggcaggagt tgcaggaggt ctcaacggac tcctaggtgg aattgttgga
     2341 acaccgctta agttaattgc aggaacgctt ccaggtatga ttctatgtgt tattgtaaac
     2401 tcattctttt ggttctgtgg agttaatggg ggacaagttt taaatgcttt tgtagatcca
     2461 gtttggttac aatttactat agaaaaccaa gaagctgtgg ctgcaggaca aacactccaa
     2521 cacattatta cattaccgtt taaagattta tttgtattta ttggtggcgg tggagcgact
     2581 attggtcttg cgatttgtct cttcctattt agtaagagtc gtgcgaataa aacattaggt
     2641 aagctagcta ttataccgtc tatttttaat atcaatacag ctattctatt tacgtttcca
     2701 acagttttaa atccgattat gctgattccg tttattgcta ctcctacaat caatgccttg
     2761 attacctatg tatcaatggc tgtaggatta gtaccctata caacaggtgt aatccttccg
     2821 tggacaatgc caccgattat aggaggcttc cttgcaacag gggctagttg gcgaggagct
     2881 ctattacaag ttgttttgat tttggtttct gtagcaattt attatccatt cttcaaaatt
     2941 gcagataaac gcaatcttga aaaagaaaaa gctactgttg gagggaaata agatggttat
     3001 cagagtattt gatcaacaga aaaatactta ttctagcttt gccttagagg aattaagtta
     3061 ctatatgaat cgggtcttta agactaacat agagcttgtc gaggagaagg aagcggatat
     3121 ttttgtagga ttagtcaata aagaggacag aaaagaccat gttcttatct cattagacaa
     3181 gggtaaggga agaattgagt ctaatacaat tgtaggttta cttattggaa tttaccgaat
     3241 gtttcatgaa tttggggttg tgtatactag accagggcgc agacatgact ttgttccaga
     3301 gttacgattt gaagattttt tagataaaca gctatctata gatgaaacag ccagttacta
     3361 tcatagggga gtatgtatag agggagcgga ttcatttgaa aatatactag atttcattga
     3421 ttggctacct aagattggga tgaacagttt tttcatccag tttgaaaatc cttactcttt
     3481 tttgaaacgt tggtatgaac atgaatttaa tccatatcta aataaagaac aattttcaaa
     3541 tgaattagta caagaattga gtgataggtt ggataaagaa ttgcaaaaaa gaggtcttat
     3601 tcatcatcgt gttggtcatg gatggacagg tgaagtttta ggttactctt caaaatttgg
     3661 ctgggaatca ggtcttagta tttcagagga gaagaaaccc tatgtcgctg aaataaacgg
     3721 gaaacgagaa ttgtttaata cggctccgat tttaaccagc ctggattttt caaatccaga
     3781 tgtagctgat aagatggtag aaattatcaa ggattatgcc aagaaaagac ctgatgttaa
     3841 ctacttacat gtatggttgt cggatgctcg taataatatt tgtgaatgcg aaaactgtag
     3901 acaagaattg gtttcggatc agtatattcg tattctcaat caattggata gggctttaac
     3961 gagtgaggga ttagatacaa agatttgttt tctgctttac catgagttgc tatgggcgcc
     4021 tcagaaagaa aaattagata atcctgaacg ctttaccatg atgtttgcac cgattacaag
     4081 aacatttgaa atgagttatg cagatgtaga ttttgacaat tccataccta cgcctaaacc
     4141 ttatctgcgt aataaaatta tacttccgaa ttctcttgag gaaaatttat cttatctttt
     4201 tgagtggcaa aaaacattta aaggagatag tttcgtatat gactatcctt tagggcgtgc
     4261 tcattatggc gatttaggct atatgaaaat tagtcaaacc atttacagag atgtatctta
     4321 tctttctaac ctacatttga acggttacat ttcgtgtcaa gaattacgtg ccggattccc
     4381 tcataatttt cctaattatg ttatggggga aatgctctgg aagaagacaa gaagttatga
     4441 agaattgatt gaagaatact tttctgcttt gtatgggtca aattggcagt ctgttgttga
     4501 atatttagaa aaattatcca gttattcctc atgtgattat tttaatgcaa ttggcagtcg
     4561 tcaaaatgat gttttagcga atcattatta tatagcttac aatctagctg ataatttttt
     4621 gccaattatt gaggaaaata tttctaagtt attaaatagt caaaaggatg aatggaaaca
     4681 gctcagttat catcgtgaat atgttgttaa gatggcgaag gctttatatc ttcaagcaac
     4741 cggaaaaaca aggcaagctc aagatgaatg gagaaatgtg ttgaattata tccgtgggca
     4801 cgaactgcta ttccaatcta atttggatgt ttatcgtgta attgaagtag caaaaaatta
     4861 cgctggtttc cacttataaa tcataagtat agaaaatgaa ccaaggtatt cagagaagat
     4921 tgatcctaaa tattatgaaa tttaaggatt tttaagatat ttagggtcga ctttctattt
     4981 atatcgtagc gaagtcattt taataatgat gtgtaaaaga tggatcaaga ttgaggagga
     5041 agaaagatga aatcaaaaga agaaataaat atgcttggtt ttacaattgt cgcttacgca
     5101 ggagatgcaa ggtcagattt gatggatgct ttggcgtttg cgagagatgg atattttgaa
     5161 caggcaagag aattggttga gtctgcaaac gactcaatag tgtctgccca tcgagaacag
     5221 actaatttat tagcggagga ggcatctgga gataattttg aagtgagttt tatcatgatt
     5281 catggtcaag ataccttgat gacaacgatg ctattgtatg atcaggtcaa gttttttatt
     5341 gatgaatatg aacgaattcg aaagattgaa gaacatattg gtttgcaatg aggattagtc
     5401 atggaaaatt tacaggttaa agccttaccg aaggagtttt tattaggagc tgctaccgct
     5461 gcttatcaag tagagggtgc aactagggta gatggcaaag gaacaaatat gtgggatgtt
     5521 tatttgcaag aaaacagtcc gtttttacca gatccggcta gtgattttta ttatcgttac
     5581 gaagaggata tagctttggc ggcagaacat ggtttgcagg ctttgcgttt atctatttct
     5641 tgggttcgta tatttcctga tatagatggg gagcctaata tattagctgt tcgttattac
     5701 catagagtct ttcagtcttg cttaaaacat aatgtgattc cgtttgtttc tttacatcat
     5761 tttgattcgc ctcagaaaat gttagaaaca ggggattggt tgaatagaga gaatattgat
     5821 cgtttcatac gatatgctcg cttttgtttc caagaattta cagaagtcaa gcattggttt
     5881 acaatcaatg aactgatgtc tcttgctgca ggtcaatata taggaggtca gtttcctcca
     5941 aatcatcatt ttcaattatc tgaagcaatt caagcgaatc ataatatgtt gttggcgcat
     6001 gctcttgcag tccgcgaatt tcatcaatta gggattgagg gaaagatagg ttgtattcat
     6061 gctttaaagc caggctatcc tattgatggg caaaaagaaa atattttggc agctaaacgg
     6121 tatgatgttt ataataataa atttctatta gatggaactt ttttgggcta ctacagtgag
     6181 gacacgcttt ttcacttgaa tcaaatattg gaagctaata attctagctt tattattgaa
     6241 gatggtgatt tagaaattat gaagagagct gcagctctta atacgatgtt tgggatgaat
     6301 tattatcgtt cagaatttat tcgtgaatac aaaggtgaaa atagacaaga atttaattca
     6361 acaggaataa aaggacagtc ttcttttaaa ttaaatgctc taggtgaatt tgtaaaaaaa
     6421 cctggtattc cgacaacaga ttgggattgg aatatttatc ctcaagggtt atttgatatg
     6481 ttgcttcgta tcaaagaaga atatcctcaa catccggtca tttatttaac tgaaaatggt
     6541 acagccctta aagaagttaa gccagagggc gagaatgata ttattgatga cagtaagaga
     6601 atccgttata ttgagcaaca tttacacaaa gttttagagg ctcgagatag aggagtcaat
     6661 attcaaggct attttatatg gtctttgcaa gatcaatttt cttgggcgaa tggctacaat
     6721 aagcgatatg gtcttttctt tgttgattat gaaacacaga agagatatat taagaaaagt
     6781 gctctttggg taaaagggct aaaacggaat taaggttagc gatttgactg atgtttaata
     6841 tattttaact atgagcttaa attttttaca ggaggagttt ttatggataa gttagtcgct
     6901 gccattgaaa agcaacaagg gaaatttgaa aaaatttcta ctaataatta tatgatggct
     6961 attaaagatg gatttattgc tactatgcct ttaattatgt tttcaagctt tttgatgatt
     7021 attattatga ttcctaaaaa tttcggagta gagttaccga gtccagctat tgcctggatg
     7081 aggaaagtgt atatgctaac catgggagtt ttgggtatta ttgtttcagg gacagttgca
     7141 aagtcattgg ctggaaatgt taatagaaaa atgcctcctg gaaaggtaat aaatgatact
     7201 tctgcaatgt tggcggccat atgtggctat cttgtattaa ctgtaacgct tgtagttgat
     7261 gagaaaacgg gatctacaag tttgtcgaca aactatttag gatctcaagg attgataact
     7321 tcgtttgtca gtgcctttat tactgtaaat gtttaccgat tctgtattaa gcgagacatt
     7381 actattcatt tacctaagga agttcctggg gctatatcac aagcttttag agatattttt
     7441 cctttttctt ttgttttact tattagtggt ttgttagata ttgtatctcg ttttagttta
     7501 gatgttcctt ttgcccaagt atttcaacaa ctattgactc ctatttttaa gggggcagaa
     7561 tcatatcctg ctatgatgtt gatttggttt atgtgtgctt tgctttggtt tgttggaatt
     7621 catggaccat ctattgtctt acctgctgtt acagctttac aactgagcaa tatggaagag
     7681 aatgctcaac ttcttgcaaa tgggcagttc ccttatcatt ctttaacacc taatttcggg
     7741 aattatatcg ctgctattgg aggaacgggg gctacctttg ttgtaccatt tattttgatt
     7801 ttctttatgc ggtctaaaca attaaaatcg gtaggtaaag ctacaattac tcctgtttta
     7861 tttgcggtaa atgaacctct tctatttggt atgcctgtta ttttgaatcc ctatcttttt
     7921 gtaccttttt tgatgactcc accagtgaat gtatttctag gaaaggtatt tattgatttc
     7981 tttggaatga atggatttta tatccagtta ccttgggcct ttcctggtcc cttgggattg
     8041 ttaattggaa cgaattttca acttatctcc tttgtatttt tatctttgat gttagttgtc
     8101 gacatattga tttatttgcc attctgtaga gcgtatgata gacagttact ggtgaaagaa
     8161 gatattgcaa gctcaaatga tattatttta gaggaggata caagtgaaat aatgccttgt
     8221 gagatagatg taataaaaag taaggagttg aaagtactgg ttctttgtgc agggtctgga
     8281 acaagtgcgc aattagccaa tgcaattaac gagggcgctc aattagcaga agttagagtg
     8341 attgcgaatt caggagcgta cggagctcat tatgatatta tgggtgttta tgatttaatt
     8401 attctggccc cacaagttcg gagttattat agagagatga aggtggatgc agaaagatta
     8461 ggtattcaga tagttgctac cagaggaatg gaatatattc atttaacaaa gagtccaagt
     8521 aaagccttac aatttgtatt ggagcattac caagctgtgt agtaagtttt tccatctttt
     8581 atttgagtaa agattttgct tacagatagg cttggattta aaaacgttcc ccctttttta
     8641 atataagaat ccctctttca caattgtaaa aagagggatt ttgtatttta tctcttagac
     8701 caagttctct tcataaagag aaggaggatt gggtaaatct ccaagcgccc tgcaatcatt
     8761 gcaaaggata ggagaatttt tgagatggga ctaaagattg agaaactaga agtggttcct
     8821 agaataggcc cgatattatt gaaacagcta aagacagcgc tggtcacgac cagaaaatca
     8881 ttgctatcta ggctgacaat aaagataagc gctagcaaaa tcatagcata gatgacaaag
     8941 tacttgagaa tcttatgctg ggtatctttg tcaatcaccg ttttattaac atggagggtc
     9001 aaaacacggt ggggcgatag gattgacaaa atttggtttt tggcaatttt tgaaaggatg
     9061 aggcctcgaa taatcttgag tccacctgca gttgatccag cagagccacc gattgccatg
     9121 aggaaaagga ggataaactg ggagaagagg ggccagttgg taatatctcc atatccaaaa
     9181 ccagttgttg taatgatgtt ggaaacctgg aagaaggtca tttcaaagct ctttgaaaac
     9241 cctgggtaga ggtagagggt gttgaggcta atcaagcctg tagaaaccag tacaatgacc
     9301 aagtaagccc gaagttcttc gtcaccaaag aaggccttga tgcgacggag catgaggtag
     9361 tagtagaggt tgaaatttac cccaaaaacc agaactccga tactgaccag ataggtaatc
     9421 agtgagctgc catagtgggc aattccgtcg ttatagacgg taaagcctcc agttcccgct
     9481 gtccccatag caatgacaaa actatcgtag agaggcatac cagctagata atagatgatg
     9541 acaaagaggg agaagagagc tagataaagg agatagagaa tctgggcagt gttttttagt
     9601 ttggatacaa ccttgccaaa aacaggacct ggaacctcag ccttcatcac ctctaggtgg
     9661 ctatttttgg cattgtccat aatagcaagt gcaaaaacaa gcactcccat ccctccaatc
     9721 aagtgggtaa aacttcgcca gaagaggagg gaacggctga gaaccgaaat gtcgttcaaa
     9781 atacttgctc cagtagttgt aaacccagaa ctaatttcaa aaaaggcatc aataacgcta
     9841 gggatttgcc cagaaaagac aaaggggaga ccaccaaaga aagaccaaag gatccaacag
     9901 agggcaacga tcaagactcc ctccttggca taaatccgtt gattttttgg cttctgtaaa
     9961 ctccctgaac cgcctaacaa tacgagaatc cctatggtcg aaaagagggc tgtaaagact
    10021 tggctcgatt cacggtaata gacagcgata gccacaggaa ccaagaggag aacagcttca
    10081 atcaaaagta actttgaaag gaggtaacga atcatacttt tattcatttc ttacctcgca
    10141 atcaagtcat aaatcttggt gatgtttggc aacaaggttg ttactaggag cttgtctcca
    10201 acttccaaca tatcctcccc agttgggaaa atagtcttgc cctttcgaat aatggctgca
    10261 ataagaaccc cttttttcaa tttcagttga gaaagaggtt tggcagtcat tttattggct
    10321 tccttgatat ggaattgcag ggtttcaatt tggccattgg ctagatggtg catggcttga
    10381 aggtctgaat actgggcatt aactcgacca cgaataaagt gcataatcgt atctacagcg
    10441 atgcttttag gtgtgatgat acttgaaaaa tcaggcgcat tgataatctc gaggagactg
    10501 gtacgattga ccttagtaat atttttctgt acacctaccc tgtcaaggaa catagatgta
    10561 atcagatttt cctcatcgac acctgttaga gtcgcaacgg catcatagtg ttgagcactt
    10621 tcttccagca ggatatcttt tgcggttcca tctccttgaa cgatgtagag atttgggaat
    10681 ttctcgctaa agaagctggc gatttcagga ttgatttcaa tgacttttgt atcgatacga
    10741 ctatctttga gaataccaag tagataatag gcaattctac ctgccccaac gatgagaagg
    10801 ctcttcacgg cgcgtgattt aaaataatta tggaagagta tcatatcgac acggttacca
    10861 gtgacaaaga ttctatcttt atcctgtaca gtcatgtcac cgcttggaat gataatttga
    10921 tgatccctct ctatcgcaca gacaatgaca ttaccaaatt ttttacgaaa atcagaaatg
    10981 ggcatttggc aaagaccgct ggtggacttg acgacaaatt ccatgaggct aacgcgtcca
    11041 ccagcaaagc gttcgacaga cagggcgttg gggaagtcaa tgatattcgc gatagcgcgg
    11101 gcagccaaga gctcaggatt aacgataaga gaaaaaccga gaatattctt ttccttgaaa
    11161 taagagttag aatattcagg gttccgcacc cgaacgatag tttctttagc tcccattttc
    11221 ttggctagaa ctgctgcaat catgttgact tcatcgtgct cagtcagggc gataaagata
    11281 tcacaatctt ggacgctggc ttgctcaaga atggcaaaat cggccccgtt accaaggata
    11341 ccaatgatat caaagcgatt gacaatatga ttgagaacag cttcgtcttg ctcaatcagc
    11401 aaaacatcat gcttttctgc aaccaaggag cgacagaggg caaaaccaac ttttccccct
    11461 ccgacaagga taattttcat aataaaacct actttttcat gatgtaacta tcataccctt
    11521 tttcaagaaa aaatgcacct actagctaat aacaagagct tttagtgaaa attcgctata
    11581 aggtaaaact ataccctaac caattgaaat agctattagc gactttctct gaaatatggt
    11641 atgataaagg atatacaagg agataaaatg aataataatt tactggtatt acaatcagac
    11701 tttggtctgg ttgatggtgc ggtatcggct atgattggag tggctttaga agagtctcca
    11761 accttaaaaa tccatcactt gacgcacgat atcacgcctt ataatatttt tgaggggagc
    11821 tatcgtctct ttcagacggt ggattactgg cctgagggaa cgacgtttgt atcggttgtc
    11881 gatccaggtg tcggttcgaa acgtaagagt gtagttgcca agactgcaaa aaatcaatac
    11941 attgtcacgc cagataatgg gacgctttcc tttatcaaga aacacgttgg cattgtagcc
    12001 attcgtgaga tttctgaggt ggccaatagg cgtcaaaaca cagagcattc ttataccttc
    12061 cacggtcgtg atgtctatgc ctatactggt gctaaactgg ccagtggtca cattactttt
    12121 gaggaagtag ggccagagct cagtgtggaa cagattgtag agcttccagt cgtagcgacc
    12181 atcatagaag atcatctggt gaagggagcc attgatattc tggatgtgcg tttcggttcg
    12241 ctttggacct ctatcacacg ggaagaattt tacaagctgg aaccagaatt tggtgatcgt
    12301 tttgaagtga ccatctatca tgctgatatg ctggtctatc aaaatcaggt tgtctatggc
    12361 aaatcatttg cagatgtgag aattgggcaa cccatccttt acatcaactc tctctatcgt
    12421 ttaggtttgg ctatcaacca aggttccttt gccaaggcct ataatgtagg tgtcggttca
    12481 tcttggacca ttgaaataaa gaaaatagaa ggataaaata ggagaatagt atggaaatca
    12541 aatttacaat taaacaagtt gttgctgtcg gaattggcgc tgccctcttt gtcgtcatcg
    12601 ggatgatcaa cattccaacc cctgttccaa atacaagcat ccagcttcag tatgcggtac
    12661 aagcgctact ttctattatt tttggaccga ttatcggttt gcttgtcggg ttgattggtc
    12721 atgcaatcaa ggactctctt gctggttatg gtctatggtg gacttggatt atcgctagcg
    12781 gactttttgg tctagttgtg ggacttttta gaaagtacgt tcgagtgatc aatggtgttt
    12841 ttgactggaa agatattctt atttttaacc tcattcaact acttgcaaat gcccttgttt
    12901 ggggtgtctt ggcaccactt ggagatgttg tgatttatca agaagcggca gaaaaagtat
    12961 ttgcacaagg gattgttgcg ggaattgcca atggtgtatc tgtagctatt gcaggaactc
    13021 ttctcttact tgcctatgca ggaacccaaa ctcgtgcagg aagtttgaaa aaggactaat
    13081 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacagtgt
//
LOCUS       DAVBNZ010000057        12973 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000057 DAVBNZ010000000
VERSION     DAVBNZ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.057"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            87..3437
                     /locus_tag="VQ860_001751"
     CDS             87..3437
                     /locus_tag="VQ860_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3120141.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            3681..3782
                     /locus_tag="VQ860_001752"
                     /pseudo
     CDS             3681..3782
                     /locus_tag="VQ860_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4023..4493)
                     /locus_tag="VQ860_001753"
     CDS             complement(4023..4493)
                     /locus_tag="VQ860_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3120142.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4510..6783)
                     /locus_tag="VQ860_001754"
     CDS             complement(4510..6783)
                     /locus_tag="VQ860_001754"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET3120143.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7129..10230
                     /locus_tag="VQ860_001755"
     CDS             7129..10230
                     /locus_tag="VQ860_001755"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET3120144.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDEQEVNLRFLSLSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YKLSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIQVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10313..11320
                     /gene="pfkA"
                     /locus_tag="VQ860_001756"
     CDS             10313..11320
                     /gene="pfkA"
                     /locus_tag="VQ860_001756"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET3120145.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11379..12884
                     /gene="pyk"
                     /locus_tag="VQ860_001757"
     CDS             11379..12884
                     /gene="pyk"
                     /locus_tag="VQ860_001757"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET3120146.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         4023 a         2203 c         2850 g         3897 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtagaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctc ttgagaaaca tatcggctat cagccaattt
      961 gctttattac aaatggcttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cacttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctaatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggctgggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcct
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagataaag
     1381 aaggagctca atcaagtcgc atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt tcactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gctactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttgttttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgttgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctccgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctctggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggctga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagccgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaattagct gcaggctgct caaaacactg ttttgaggtt gtagataaga
     3781 ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta
     3841 accataccta cggcaaggcg acgttgacgc ggattgaaga gattttcgaa gagtataaat
     3901 cttcctagga taaagcaaaa cgcatagtat caagtgttga aaacccttga tactatgcgt
     3961 tttctgatgt taaagacttt ctaccagttt ttttaagcat aattgttagt tgtagtcatt
     4021 tattattctt caaagaaaaa tggtggggcg aattttttca gttcttcaaa gcacttttga
     4081 gcagtatctg catcttcaca gatgataaga cagacatcat taccacaaag ggtagcgata
     4141 gcgtcaggga agctcaaagt atcaatgata gaaccaaagg attgagccag tccaggaagg
     4201 gtttttagta ggacttggtg ttgaactggg cgcatccaga caagggcgtc ttccatgtag
     4261 agttcgagac gtttttccca ttttgagatg gaaccattgt taagaacata ataagcgcta
     4321 tcttcttcgc ggacttttga taggttcata tttttgatgt cgcgtgagag ggttgcctgg
     4381 gttacttgaa tgtcgttctt agcaagaagg gcttgcaact cagcctgtgt atgaatcttg
     4441 ttttttgtga taagagcgcg tataagttgg tggcggtgtt ctgatttatt cataataatg
     4501 taactccttt tagcaaggta aggtaagcat ggactgagcg aggtcgacag tcaagtggta
     4561 gtctgtattg tcacggatgg tgatttcaaa gtcagtagta tagaggacta aacggagagt
     4621 gtctccttct tttagcttgt aaatagttgg ctgcagttca aattgaacgt ccatccattc
     4681 atctgcagta atatcctcta ctaacagtaa atcatttcta ttttgtaaat taaggtaacc
     4741 ttttgtcacg actcgttgtg cctctggtct aaatggcaat tcacagagat tttccaacat
     4801 gtgatagcga ccgttatcaa tggttctagc acttaaaata gctggataag gttgtaggta
     4861 tttcttttgc ccaaattcta gcagttgggc agataagagc cccttgtttg tactggattt
     4921 gatacgaaga ttgagctgag cgcgaccgtt taggtggaga tctttagtca caggaaggtt
     4981 aatagtaatc tgattagctt tcccttgata gagctctgta ttgaaggttt ggtatgtctt
     5041 actatagcgc tcaaaatcct tatctgggta ctggttttga atagcttgct cttcttgacc
     5101 aagtgagaag gttttacagt tttcttgccc accgaagtta tcaagtgata accaagtctg
     5161 tggagctgta ttgtcctgcc agataacagt aggaagttga aagtctgttt cctgtcctag
     5221 taatttcttg gttaataagg catttatgga ctcacggaag tcaattgatt gccaattgtt
     5281 catgtaaaca tgggcaccat tatggaaaaa gagatgcttg tgtatatgag taggaagagc
     5341 atggaacatc tggtaaacat gaagtggttt gacattccaa tcctgagaac catgagtaaa
     5401 gacaacctct gcctttactt tatgggcatt gagcagataa ttgcggtcat gccaaaactg
     5461 attgtagtcc ccagtttttc ggtctagctg agctttcact ttttctaagt cagcttggtg
     5521 agcttcattg ccacggatat agtcgccagc taagagatta cgagaatagg ttaactcagc
     5581 aagggagtca aagtcctcac ctggataacc acctgggcta gtcaccagac cgttttcacg
     5641 gtagtagttg taccatgatg aaattcctgc ctcggcaatg ataacttcta aaccatcgac
     5701 tcctgtagtc gcaagaccat tggacatggt acctagatag gaaagtcccg ttgtagcaac
     5761 ttttccgttt gaccaatcag ccttgacttg acgctggcgc gtgtgatcag taaaggcacg
     5821 gcaacggccg ttaagccaat cgatgacatt tttataagcc tcgatttgct ggtagtctcc
     5881 attagtcatg aaacctgtcg agtctttggt accaacacct gagacataga gattggcaaa
     5941 gcctctcgga aggaagtagt cgtttagtgt atagctagag ttgatgtgag ttagcttttc
     6001 ctcagcctct gctataagct cagcttgacc ttggggttgg acgagattta gttgaggttt
     6061 ctctagctca atcttgtgag gaagcttaac ctcaagctcg ccctccatct tgtagagagc
     6121 cttgtcacta gccttgtcat tggttccctg atgataaggg ctggctgtca tgatggcagg
     6181 gatttttcca tcaaaacgag ggcgaataat gctaaccttt actaggtctg atagcccttt
     6241 ttggtcagta tcgacacgag actcaacgta aacgacttca cgaatgacat cctggttaga
     6301 aaaagtagcc aaactcttgc cgttaaagta gtggtagtca ttatcctccg gaataagacc
     6361 atcactaaca agttggtcga taagagtatt tccttttttg gtgcgagtat tgagtaactg
     6421 atagagattt tcaatcaagt caccatatat aatgggaaat ccagtttctt tacgaaaaac
     6481 gtcactatct tcgaagtcaa ccaaataaga aaagcctaaa agttgaaaag caacagtata
     6541 aaaaatatct gctgtcagtt catcttctga ttgaaaaaat gtcagcaggt ctgttttttt
     6601 atcagctgct aggatagaaa gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg
     6661 taaaaaggtt tcaagtgagt ctttgtgatt ggctgtattt tgtaaatcaa agccacattt
     6721 ttttagctca gataagacat tttcttttgg aaaattgata taactatatt gattaaaacg
     6781 catagaacct ccatatagaa tgacagttaa ggttattata tcaaaaaaaa agcagaaagg
     6841 gaattgttaa cttcaaaagg aaataatcca ataaaaatga ataaagtact aaattcaata
     6901 tagagaacag agtaacaata agaataatag atagggtata aaagttctag gagatttata
     6961 ttatatgctt tctattttta tatacaatat agtataaata taaaaatgat gacaaaaata
     7021 caaatgaata gaaaataaat tagtaagctg atgaaatttt tctcaagaga agccatttat
     7081 aggtgaaaat ggtataatat agtgagaagg atagaggaga agtgtaaatt gatcgcacaa
     7141 ctagatacaa aaacagtcta tagttttatg gaaagcgtca tttcgatcga aaagtatgtg
     7201 agagcagcta aagaatacgg ctacactcat ttggctatga tggatattga caatctttat
     7261 ggcgctttcg actttctaga gattacaaaa aaatacggca ttcatccttt gctagggctt
     7321 gaaatgacag tgtttgtaga tgaacaggaa gtgaatttgc gctttttatc tctatctagt
     7381 gtgggctatc agcagttgat gaagctttcg acagccaaga tgcaggggga gaaaacttgg
     7441 tcagtcctgt cccagtacct ggaggatatc gcggtcattg tgccttattt tgatagagtt
     7501 gagtcgttag aactaggctg tgattactat ataggggttt atccagaaac actagcaagc
     7561 gaatttcatc atcctatctt acctctttat cgggtcaacg cttttgaaag cagggataga
     7621 gaagttcttc aagttttaac agcgattaaa gaaaatctac cgctcagaga agttcccttg
     7681 cgttcgagac aagatgtctt tatatcagca agttctttag agaaactatt ccaagagtgt
     7741 tttccgcaag ctttggacaa tttagaaaag cttatttcag gcatttctta cgacttggat
     7801 actagtctga aactgcctcg ttttaatcca gctagaccag cagtagagga gttgagagag
     7861 cgtgctgaac tggggcttgt tcagaagggg ttgactagta aagaatatca agatagacta
     7921 gaccaagaat tgtctgttat tcatgatatg ggctttgatg attatttctt ggttgtttgg
     7981 gatttgttgc gttttggacg atcgaatggc tattatatgg gaatgggaag gggttctgca
     8041 gtaggcagtt tggtttctta tgccttagac atcacgggga ttgacccagt agagaaaaat
     8101 ctgatttttg aacgctttct taatcgtgaa cgctatacca tgcctgatat tgatattgat
     8161 atcccagata tttatcgtcc agattttatc agatatgttg gtaataaata tggtagtaaa
     8221 catgcggcac aaatcgttac tttttcaacc tttggagcca agcaagctct tcgagatgtc
     8281 ttgaaacgct ttggtgtgcc agagtataaa ttatctgcaa ttactaagaa aatcagtttt
     8341 cgtgacaatc ttaagtcggc ctatgagggc aatctccagt ttcgtcagca aatcaatagt
     8401 aagttagaat accaaaaagc ttttgagatt gcttgcaaga tagagggcta tccaaggcaa
     8461 acctctgtcc atgcggctgg tgttgtaatt agtgaccaag atttaaccaa ctacattcct
     8521 ctaaagtatg gtgatgaaat tccactgact cagtatgatg ctcatggagt tgaggctagc
     8581 ggacttttga agatggactt tctgggacta cgaaatttga cctttgtcca gaagatgcaa
     8641 gagttgcttg ctgaaacaga aggtattcac cttaaaattg aagaaataga tttggaagac
     8701 aaagaaacgt tagatttatt tgcctctgga aatacaaaag gtatctttca atttgagcaa
     8761 cctggtgcca ttcgcttgct caaacgtgtt caaccagtct gttttgaaga tgtcgtagca
     8821 actacttctc taaatcgacc aggtgcaagt gactacatca ataattttgt ggcaaggaag
     8881 catgggcagg aagaagtgac tgttctagat tcagctctgg aggatatttt ggctccaact
     8941 tatggcatta tgctctatca ggagcaggtt atgcaggttg ctcagcgatt tgctggattt
     9001 agtcttggga aggccgatat tttgcgtcga gctatgggta aaaaggatgc ctctgctatg
     9061 catgagatga gggcttcctt tattcaaggc tccatagaag caggccatac tgcggaaaaa
     9121 gcagagcagg tttttgatgt tatggagaag tttgcaggtt atggatttaa tagatctcat
     9181 gcctacgcct actcagcctt ggccttccag ttggcttatt tcaaaacgca ttatccagcc
     9241 attttttatc aggtcatgtt aaattattcc aacagtgatt acttaataga tgcacttgaa
     9301 gcaggttttg aagtagcctc tctatccatc aatactattc cctatcacga taaaattgcc
     9361 aacaagtcta tctatatagg tttgaaatcg attaaggggc tcagcaagga cttggcgctt
     9421 tggattattg aacatagacc ttattctaac attgaagatt ttatagctaa attacctgag
     9481 aattatctga aacttcctct gctagaacct ttggtaaaag ttggtctttt cgattcattt
     9541 gaaaaaaatc gtcaaaaagt atttaataac ttagctaatc tatttgaatt tgtgaaagag
     9601 ttgggaagtt tgtttggaga tgctatttat agttggcagg aatcggaaga ttggacggaa
     9661 caagaaaaat tttatatgga acaagagctt ttagggatag gtgtcagcaa acatccacta
     9721 caagctattg caagtaaggc tatttacccg attaccccaa tcggaaattt gtcagaaaat
     9781 agctatgcta ttattttggt tgaagttcag aaaataaaag tgattcgtac caaaaagggt
     9841 gaaaatatgg ccttcttaca ggcagatgat agtaagaaaa aattggatgt cactctcttt
     9901 tcagacttat atcgtcaggt tggacaggaa ataaaagagg gagccttcta ctatgtaaaa
     9961 ggaaaaatac aatcacgtga tggccgtttg caaatgattg cacaagaaat aagagaagca
    10021 gttgctgaac gcttttggat acaggtgaaa aatcatgaat cggatcaaga aatttcacgt
    10081 attttagaac aatttaaagg cccaatccaa gtcatcatcc ggtatgaaga ggaacagaaa
    10141 accatcgttt ctccccatca ttttgtagct aaatccaatg aattagagga gaaattgaat
    10201 gaaatcgtta tgaaaacgat ttatcgctaa aaatacggaa aatagaagaa ttttaaaatc
    10261 aaatgtgata taatcaagaa gaatgttaaa agaaaaagga gcataaacca atatgaaacg
    10321 tattgctgtt ttgactagtg gcggagacgc acctggtatg aacgctgcta tccgtgcagt
    10381 tgttcgtcaa gcaatttcag aaggaatgga agtgtttggt atctatgacg gatatgctgg
    10441 tatggttgcc ggtgaaattc atcccctaga tgcagcttca gtaggagaca tcatttctcg
    10501 tggtggtact tttcttcact cagctcgtta cccagagttc gctcaacttg aagggcaact
    10561 taaagggatt gagcaattga aaaaacacgg aattgaaggt gtagttgtta tcggtggtga
    10621 cggatcttac cacggcgcta tgcgtttgac tgaacatggc ttcccagcta ttggtcttcc
    10681 aggtacaatc gataacgata tcgttggtac tgactttaca atcggttttg acacagcggt
    10741 tactactgcc atggacgcta tcgataagat tcgtgataca tcatcaagtc accgtcgtac
    10801 ttttgtaatc gaagttatgg gacgtaacgc tggtgatatc gctctttggg ctggtattgc
    10861 aactggtgct gatgaaatca tcatccctga agcaggcttc aagatggaag atatcgtagc
    10921 aagcatcaaa gctggttatg aatgtggtaa aaaacacaat atcatcgtct tagctgaagg
    10981 tgtgatgtca gcggctgaat ttggtcaaaa acttaaagaa gctggagata caagcgacct
    11041 tcgtgtaaca gaacttggac atattcaacg tggtggttct ccaactgcgc gtgaccgtgt
    11101 tttagcgtca cgtatgggtg cacatgctgt taaacttctt aaagaaggta tcggtggtgt
    11161 tgcggttggt attcgtaacg aaaaaatggt tgaaaatcca attcttggta ctgcagaaga
    11221 aggggcattg tttagcctta ctgcagaagg taagattgtg gttaacaacc cgcacaaagc
    11281 cgatattgag ctatctagct tgaataagag cttgtcataa tttacaattt agttaataag
    11341 accaaaaagg tcatatatat aaaggagtca caaaaatcat gaacaaacgt gtaaaaatcg
    11401 ttgcaacttt gggtcctgcg gtagaaatcc gtggtggtaa aaaattcggt gaggacggat
    11461 actggggtga aaaacttgat gttgaagctt cagctaaaaa cattgctaaa ttgattgaag
    11521 ctggtgctaa cacattccga ttcaacttct cacacggcga ccaccaagaa caaggtgagc
    11581 gtatggcaac tgttaaactt gcggaaaaaa ttgcaggtaa aaaagttggt ttccttcttg
    11641 atacaaaagg acctgaaatc cgtacagaat tgttcgaagg tgaagctaaa gaatattcat
    11701 acaaaactgg tgaaaaaatt cgtgttgcaa ctaaacaagg aatcaaatca actcgtgaag
    11761 tgattgcgtt gaacgttgct ggtgctcttg atatctatga tgatgttgaa gttggtcgtc
    11821 aagttttggt tgacgatggt aaacttggtc ttcgtgtggt tgctaaagat gatgcaactc
    11881 gtgaatttga agttgaagtt gaaaacgatg gtatcatcgc taaacaaaaa ggtgtgaaca
    11941 tccctaacac taaaattcct ttcccagctc ttgctgaacg cgataacgac gatatccgtt
    12001 tcggtcttga acaaggtatc aacttcatcg caatttcatt cgtacgtact gcaaaagatg
    12061 tgaacgaagt tcgtgcaatc tgtgaagaaa ctggaaacgg acatgttcaa ttgttcgcta
    12121 aaatcgaaaa ccaacaaggt atcgataact tagacgaaat catcgaagca gctgatggta
    12181 ttatgattgc tcgtggtgat atgggtatcg aagtaccgtt cgaaatggtt ccagtttatc
    12241 aaaaaatgat tatcaagaaa gtcaatgctg caggtaaagt tgttatcact gcaacaaaca
    12301 tgcttgaaac aatgactgaa aaaccacgtg caactcgttc agaagtatca gacgtattca
    12361 acgctgttat cgacggaact gacgctacaa tgctgtcagg cgagtctgca aacggtaaat
    12421 acccactcga gtcagtaact acaatggcta caatcgacaa gaacgctcaa gctcttctta
    12481 atgaatacgg acgtcttgat tcagattcat ttgagcgtaa ctctaagaca gaagtaatgg
    12541 cttctgctgt taaagatgct actaactcaa tggatatcaa attggttgta actcttacta
    12601 agacaggtca tactgcacgt ttgatttcta aataccgtcc aaatgctgac atcttagcat
    12661 tgacatttga cgaattgaca gaacgtggct tgatgttgaa ctggggtgtt atcccaatgt
    12721 tgacagatgc tccatcttca actgacgata tgttcgaaat cgctgaacgt aaagcggtag
    12781 aagcaggtct cgttgagtca ggcgatgata tcgttatcgt tgctggtgtg ccagtaggag
    12841 aagctgttcg cacaaacaca atgcgtatcc gcacagtacg ttaagaaaaa tataaaaacc
    12901 tatcatatcc agctttctag cctgtatgat gggctctttt tttgtccagg gggcaaaact
    12961 ttcataatgg att
//
LOCUS       DAVBNZ010000058        12086 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000058 DAVBNZ010000000
VERSION     DAVBNZ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12086
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.058"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            413..640
                     /locus_tag="VQ860_001758"
     CDS             413..640
                     /locus_tag="VQ860_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120147.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            928..4065
                     /gene="nanA"
                     /locus_tag="VQ860_001759"
     CDS             928..4065
                     /gene="nanA"
                     /locus_tag="VQ860_001759"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET3120148.1"
                     /translation="MNRSIQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDASAPRFYNLFSVSS
                     DTKENEYFTMSVLDNTALIEGRGANGEQFYDKYTDAPLKVRPGQWNSVTFTVEQPTAE
                     LPHGRVRLYVNGVLSRTSLKSGNFIKDMPDVNQAQLGATKRGNKTVWGSNLQVRNLTV
                     YDRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTARFMTQYDTKTLLFTVDSEDMGQKVTGLAEG
                     AIESMHNLPVSVAGTKLSNGMNGSEAAVHEVPEYTGPLGTSGEEPAPTVEKPEYTGPL
                     GTSGEEPAPTVEKPEYTGPLGTSGEEPAPTVEKPEYTGPLGTAGEEAAPTVEKPEFTG
                     GVNGTEPAVHEIAEYKGSDSLVTLTTKKDYTYKAPLAQQALPETGNKESDLLASLGLT
                     AFFLGLFTLGKKREQ"
     gene            5081..5533
                     /locus_tag="VQ860_001760"
     CDS             5081..5533
                     /locus_tag="VQ860_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3120149.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFIYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5552..6889
                     /locus_tag="VQ860_001761"
     CDS             5552..6889
                     /locus_tag="VQ860_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3120150.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6968..7852
                     /locus_tag="VQ860_001762"
     CDS             6968..7852
                     /locus_tag="VQ860_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3120151.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7852..8685
                     /locus_tag="VQ860_001763"
     CDS             7852..8685
                     /locus_tag="VQ860_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3120152.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8703..10796
                     /gene="nanB"
                     /locus_tag="VQ860_001764"
     CDS             8703..10796
                     /gene="nanB"
                     /locus_tag="VQ860_001764"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET3120153.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKADFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     NETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10808..11911
                     /locus_tag="VQ860_001765"
     CDS             10808..11911
                     /locus_tag="VQ860_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3120154.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
BASE COUNT         4065 a         1927 c         2532 g         3562 t
ORIGIN      
        1 agttctatct gccacctcaa aacggtgttt tgagctgact ttgtcagtct tatctacaac
       61 ctcaaaacag tgttttgagc atcatgcggc tagcttctta gtttgctctt tgattttcat
      121 tgagtataaa aacagatgag tttctgtttt ctttttatgg actataaatg ttcagctgaa
      181 actactttca aggacattat tatataaaag aattttttga aactaaaatc tactatatta
      241 cactatattg aaagcgtttt aaaaatgagg tataataaat ttactaacgc ttataaaaag
      301 tgatagaatc tatctttatg tatatttaaa gatagattgc tgtaaaaata gtagtagcta
      361 tgcgaaataa cagatagaga gaagggattg aagcttagaa aaggggaata atatgatatt
      421 taaggcattc aagacaaaaa agcagagaaa aagacaagtt gaactacttt tgacagtttt
      481 tttcgacagt tttctgattg atttatttct tcacttattt gggattgtcc cctttaagct
      541 ggataagatt ctgattgtga gcttgattat atttcccatt atttctacaa gtatttatgc
      601 ttatgaaaag ctatttgaaa aagtgttcga taaggattga gcaggaagta tggtataaat
      661 agcataagct gatgtccatc atttgcttat aaagagatat tttagtttaa ttgcagcggt
      721 gccctggtag ataaactaga ttggcaggag tctgattgga gaaaggagag gggaaaattg
      781 gcaccaattt gagatagttt gtttagttca tttttgtcat ttaaatgaac tgtagtaaaa
      841 gaaagttaat aaaagacaaa ctaagtgcat tttctggagt aaatgtctta tttcagaaat
      901 cgggatatag atatagagag gatcagtatg aatcggagta ttcaagaacg taagtgtcgt
      961 tatagcatta ggaaactatc ggtaggagcg gtttctatga ttgtaggagc agtggtattt
     1021 ggaacgtctc ctgttttagc tcaagaaggg gcaagtgagc aacctctggc aaatgaaact
     1081 caactttcgg gggggagctc aaccctaact gatacagaaa agagccagcc ttcttcagag
     1141 actgaacttt ctggcaataa gcaagaacaa gaaaggaaag ataagcaaga agaaaaaatt
     1201 ccaagagatt actatgcacg agatttggaa aatgtcgaaa cagtgataga aaaagaagat
     1261 gttgaaacca atgcttcaaa tggtcagaga gttgatttat caagtgaact agataaacta
     1321 aagaaacttg aaaacgcaac agttcacatg gagtttaagc cagatgcatc agctccacgc
     1381 ttttacaatc tcttctctgt atccagtgac accaaggaaa atgagtactt tactatgtcg
     1441 gtccttgata atacagctct tattgaaggg cgtggcgcta acggagagca gttctatgat
     1501 aagtatacag atgctccttt gaaagttcgc ccaggacaat ggaattccgt gacctttact
     1561 gtcgaacaac cgacagcgga gttacctcat ggacgagttc gtctctatgt gaacggtgtc
     1621 ttatctcgaa caagtctcaa atctggtaac tttatcaaag atatgccaga tgttaatcaa
     1681 gctcaacttg gagcaaccaa acggggcaat aagacagttt ggggaagcaa tctacaagtt
     1741 cgaaacctaa ccgtctatga tcgtgcctta agcccagaag aagttcagac gagaagccaa
     1801 ctatttgaaa gaggtgattt ggagaagaaa cttccagaag gtgcgaaaat ctcagagaaa
     1861 gaagacgtct ttgaaggggg aatgaacaac aaaccaaata aagatggaat taagagttat
     1921 cgtattccag ctcttctcaa gacagataaa ggaactttga tcgcaggtgc agatgaacgc
     1981 cgtctccatt cgagtgactg gggtgatatc ggtatggtca tcagacgtag tgaagataat
     2041 ggtaaaactt ggggtgaccg agtaaccatt accaacttac gtgacaatcc aaaagcttct
     2101 gacccatcga tcggttcacc agtgaatatc gatatggtgt tggttcaaga tcctgaaacc
     2161 aaacgaatct tttctatcta tgacatgttc ccagaaggga agggaatctt tggaatgtct
     2221 tcacaaaaag aagaagccta caaaaaaatc gatggaaaaa cctatcaaat cctctaccgt
     2281 gaaggagaaa agggagctta taccattcga gaaaatggta ctgtctatac accagatggt
     2341 aaggcgacag actatcgcgt tgttgtagat cctgttaaac cagcctatag cgacaagggt
     2401 gatctataca agggtgacca attactagga aatatctact tcacaacaaa caaaacttct
     2461 ccatttagaa ttgccaagga tagctatcta tggatgtcct acagtgatga cgacgggaag
     2521 acatggtcag ctcctcaaga tattactccg atggtcaaag ccgattggat gaaattcttg
     2581 ggtgtaggtc ctggaacagg aattgtactt cggaatgggc ctcacaaggg acggattttg
     2641 ataccggttt atacgactaa taatgtatct cacttagatg gctcgcaatc ttctcgtgtc
     2701 atctattcag atgatcatgg aaaaacttgg catgctggag aagcggtcaa cgataaccgt
     2761 caggtagacg gtcaaaagat ccactcttct acgatgaaca atagacgtgc gcaaaataca
     2821 gaatcaacgg tggtacaact aaacaatgga gatgttaaac tctttatgcg tggtttgact
     2881 ggagatcttc aggttgctac aagtaaagac ggaggagtga cttgggagaa ggatatcaaa
     2941 cgttatccac aggttaaaga tgtctatgtt caaatgtctg ctatccatac gatgcacgaa
     3001 ggaaaagaat acatcatcct cagtaatgca ggtggaccga aacgtgaaaa tgggatggtc
     3061 cacttggcac gtgtcgaaga aaatggtgag ttgacttggc tcaaacacaa tccaattcaa
     3121 aaaggagagt ttgcctataa ttcgctccaa gaattaggaa atggggagta tggcatcttg
     3181 tatgaacata ctgaaaaagg acaaaatgcc tataccctat catttagaaa atttaattgg
     3241 gaatttttga gcaaaaatct gatttctcct accgaagcga aagtgaagcg aactagagag
     3301 atgggcaaag gagagatggg caaaggagtt attggcttgg agttcgactc agaagtattg
     3361 gtcaacaagg ctccaaccct tcaattggca aatggtaaaa cagcacgctt catgacccag
     3421 tatgatacaa aaaccctcct atttacagtg gattcagagg atatgggtca aaaagttaca
     3481 ggtttggcag aaggtgcaat tgaaagtatg cataatttac cagtctctgt ggcgggcact
     3541 aagctttcga atggaatgaa cggaagtgaa gctgctgttc atgaagtgcc agaatacaca
     3601 ggcccattag ggacatccgg cgaagagcca gccccgacag tcgagaagcc agaatataca
     3661 ggtccattag ggacatccgg tgaagagcca gctccaacag tcgagaagcc agaatacaca
     3721 ggcccactag ggacatccgg cgaagagcca gccccgacag tcgagaagcc agaatacaca
     3781 ggcccactag ggacagctgg tgaagaagca gctccaacag tcgagaagcc agaatttaca
     3841 gggggagtta atggtacaga gccagctgtt catgaaatcg cagagtataa gggatctgat
     3901 tcgcttgtaa ctcttactac aaaaaaagat tatacttaca aagctcctct tgctcagcag
     3961 gcacttcctg aaacaggaaa caaggagagt gacctcctag cttcactagg actaacagct
     4021 ttcttccttg gtctgtttac gctagggaaa aagagagaac aataagagaa gaattctaaa
     4081 catttgattt tgtaaaaata gaaggagata gcaggttttc aagcctgcta tctttttttg
     4141 atgacattca ggctgatacg aaatcataag aggtctgaaa ctactttcag agtagtctgt
     4201 tctataaaat atagtagatt gaaataagat gtgaacaact ctatcaggaa agtcaaatta
     4261 atttatagaa aaattttagc agtcaaggtg tactgttata gattcaatat attatgcgac
     4321 tattaacctt gtcttctcct aaaattgact ttcttgtttt cttatcttgt ccactcgaaa
     4381 caagtattgt aagaatttga ttatttttga aagtactttt aatatacttg atatagttaa
     4441 aaaagatttg aaactaaatt ccaaattaga aaaagacttg aaatactaaa aaaaaaaaag
     4501 tatactctaa ttgaaaacgg taacaaaact aatttagaga atgaaatata gagtatttct
     4561 ctcttaaaag tttttggtga aacgagatgt agaaaggaga tttagccaaa gagtctatta
     4621 gtgctagaat aatagattag aattatttta gaaaaacgaa gtgagcagct tataaattca
     4681 agtccccaaa tagattcata ctagtatctt ttgcaaaaaa taaagggcga cttccttcat
     4741 gaatatcaat ttcatctata aggaaggtag ctaattgaac taacttattt attctgtttg
     4801 tcgctagaaa aatcagacct ccttgtgaag attgaggaga tactgaatga aaatcaaaga
     4861 agaaactagc aagctagtag cagattgccc aaaacaccgc tttgaggttg tagataagac
     4921 tgacgtatat aatccaaggt gaagcgactg tggtttgaag agattttcaa agagtatagg
     4981 ctagagagta gtgtttttat gtccttctag tagaaaatgc tagacagaag aatggggaac
     5041 ttggatagga aaaatagatt gagaaaggag gttagaagag atgattatta caaaaattag
     5101 ccgtttagga acttatgtgg gagtcaatcc acattttgca acattaatag attttctaga
     5161 aaaaacagga ctagaaaatt taacagaagg ttcgattgct atcgatggta atcgattgtt
     5221 tgggaattgc tttatttatc tagcagatgg tcaagcaggg gctttctttg aaacacacca
     5281 aaaatatttg gatattcatt tagttttgga aaacgaagaa gccatggctg ttacatcgcc
     5341 ggaaaatgta agcgttaccc aagaatatga tgaagagaaa gatattgaat tatacacagg
     5401 gaaagtggaa cagttggttc atttgagagc tggtgaatgc ctcatcactt ttccagaaga
     5461 tttacatcaa cccaaggttc gtataaatga tgaacctgtg aaaaaagttg tctttaaagt
     5521 tgcgatttct taatgtagaa agagaagaac gatgaaaaaa atgagaaagt ttttatgtct
     5581 agctggaatt gcgctagcgg ctgttgcctt ggtagcttgt tcaggaaaaa aagaagctac
     5641 aactagtact gaaccaccaa cagaattatc tggtgagatt acaatgtggc actcctttac
     5701 tcaaggaccc cgtttagaaa gtattcaaaa atcagcagat gctttcatgc aaaagcatcc
     5761 aaaaacgaaa atcaagattg aaacattttc ttggaatgac ttctatacta aatggactac
     5821 aggtttagca aatggaaatg tgccagatat cagtacagct cttcctaacc aagtaatgga
     5881 aatggtcaac tcagatgctt tggttccgct aaatgattct atcaagcgta ttggacaaga
     5941 taaatttaac gaaactgcct taaatgaagc aaaaatcgga gatgattact actctgttcc
     6001 tctttattca catgcacaag tcatgtgggt tagaacagat ttgttaaaag aacataatat
     6061 tgaggttcct aaaacttggg atcaactcta tgaagcttct aaaaaattga aagaagctgg
     6121 agtttatggc ttgtctgttc cgtttggaac aaatgactta atggcaacac gtttcttgaa
     6181 cttctacgta cgtagtggtg gaggaagcct cttaacaaaa gatcttaaag cagacttgac
     6241 aagccaactt gctcaagatg gtattaaata ctgggttaaa ttgtataaag aaatctcacc
     6301 tcaagattct ttgaatttta atgtccttca acaagctacc ttgttctatc aaggaaaaac
     6361 agcatttgac tttaactctg gcttccatat cggaggaatt aatgccaaca gtcctcaatt
     6421 gattgattcg attgatgctt atcctattcc aaaaatcaaa gagtctgata aagaccaagg
     6481 aattgaaacc tcaaacattc caatggttgt ttggaaaaat tcaaaacatc cagaagttgc
     6541 taaagcattc ttagaagcac tttataatga agaagactac gttaaattcc ttgattcaac
     6601 tccagtaggt atgttgccaa ctattaaggg gattagcgat tctgcagcct ataaagaaaa
     6661 tgaaactcgt aagaagttta aacatgctga agaagtaatt actgaagctg ttaaaaaagg
     6721 tactgctatt ggttatgaaa atggaccaag tgtacaagct ggtatgttga ctaaccaaca
     6781 cattattgaa caaatgttcc aagatatcat tacaaatgga acagatccta tgaaagcagc
     6841 aaaagaagca gaaaaacaat taaacgattt atttgaggct gttcagtaga tgtaaaagac
     6901 tagaaaatag gtgggctagt gatctgaaaa gctctagccc aattttgtaa aagaagggag
     6961 aaggagaatg gttaaagaac gtaatttaac tcgctggata tttgttttgc cagctatgat
     7021 tatcgtagga ttactctttg tttatccgtt tttctcgagt attttttata gctttaccaa
     7081 taagcatttg attatgccta attataaatt tgttggtttg gctaactata aagctgtgct
     7141 atcagatccc aacttcttta atgcgttctt taattcaatt aagtggaccg ttttctcatt
     7201 agttggtcaa gttttagtag ggtttgtgtt ggctttagct cttcacagag tacgccactt
     7261 caagaaatta tataggacct tattgattgt tccttgggca tttcctacca tcgttattgc
     7321 cttctcttgg cagtggattc taaacggggt ttatggctac ttacctaatc taatcgtaaa
     7381 attaggttta atggaacata cacctgcatt tttgacagat agtacatggg cattcctatg
     7441 tttggtgttt atcaacattt ggtttggagc accaatgatt atggttaatg tgctttcagc
     7501 tttgcaaaca gtaccagaag aacaatttga ggctgctaag atagatggtg cttcaagttg
     7561 gcaggtgttc aagtttatcg tctttccaca tattaaagtg gttgtaggac ttctagttgt
     7621 tttgagaact gtatggatct ttaataactt tgacattatc tacctcatta ctggtggtgg
     7681 accagccaat gctacaacga cgcttccaat ttttgcttac aacctgggtt ggggaactaa
     7741 attgttgggt cgtgcttcag cagttacagt attgctcttt atcttcttgg tggcgatttg
     7801 ctttatctac tttgctatca tcagtaagtg ggaaaaggag ggtagaaaat aatgaagaag
     7861 aaatccagta tttatttaga tattctctca catgtacttt tagttggtgc gaccatcgtt
     7921 gcagttttcc cattggtatg gattatcata tcttctgtca aagggaaagg ggaattaact
     7981 cagtatccaa cacgattttg gcctgaacag tttacattag attatttcac tcatgttatc
     8041 aacgatttgc acttcattga taacattcga aacagtttaa tcattgcctt ggctacaacc
     8101 ctcattgcga ttattatttc tgctatggca gcctatggta ttgttcgatt ctttcctaaa
     8161 ttgggagcaa tcatgtcgag actactcgtc attacctata ttttcccacc aattttgtta
     8221 gcaattccct attcaattgc cattgctaaa gttgggttaa caaatagttt atttggcttg
     8281 atgatggttt atctatcttt tagtgttcca tatgcagttt ggctcttagt tggatttttc
     8341 caaacagttc caattggaat tgaagaagcg gctagaattg atggtgcaaa taaatttgtt
     8401 acgttttata aagttgtgct accgattgta gcaccaggta ttgtagcaac agctatttat
     8461 acatttatca atgcttggaa tgaattcctg tatgccttga ttttgattaa caatacagga
     8521 aagatgacag tagcagtagc ccttcgttca cttaatggtt cagaaatact agactgggga
     8581 gatatgatgg cagcgtctgt tattgtagtt cttccatcaa ttattttctt ctctatcatc
     8641 caaaataaga ttgcaagtgg attatcagaa ggatctgtga agtagacgaa agaaggaaaa
     8701 aaatgaataa aagaggtctt tattcaaaac taggaatttc tgttgtaggc attagtcttt
     8761 taatgggagt tcccactttg attcatgcga atgaattaaa ctatggtcaa ctgtccatat
     8821 ctcctatttt tcaaggaggt tcatatcaac tgaacaataa gagtatagat atcagctctt
     8881 tgttattaga taaattgtct ggagagagtc agacagtagt aatgaaattt aaagcagatg
     8941 aaccaaactc tcttcaagct ttgtttggcc tatctaatag taaagcagac tttaaaaata
     9001 attacttttc aattttcatg agagattctg gtgagatagg tgtagaaata agagacgccc
     9061 aaaagggaat aaattattta ttttccagac cagcttcatt atggggaaaa cataaaggac
     9121 aggcagttga aaatacacta gtatttgtat ctgattctaa agataaaaca tacacaatgt
     9181 atgttaatgg aatagaagtg ttctctgaaa cagttgatac atttttgcca atttcaaata
     9241 taaatggtat agataaggca acactaggag ctgttaatcg tgaaggtaag gaacattacc
     9301 tcgcaaaagg aagtattgat gaaatcagtc tatttaacaa agcaattagt gatcaggaag
     9361 tttcaactat tcccttgtca aatccatttc agttaatttt ccaatcagga gattctactc
     9421 aagctaacta ttttagaata ccgacactat atacattaag tagtggaaga gttctatcaa
     9481 gtattgatgc acgttatggt gggactcatg attctaaaag taagattaat attgccactt
     9541 cttatagtga tgataatggg aaaacgtgga gtgagccaat ttttgctatg aagtttaatg
     9601 actatgagga gcagttagtt tactggccac gagataataa attaaagaat agtcaaatta
     9661 gtggaagtgc ttcattcata gattcatcca ttgttgaaga taaaaaatct gggaaaacga
     9721 tattactagc tgatgttatg cctgcgggta ttggaaataa taatgcaaat aaagccgact
     9781 caggttttaa agaaataaat ggtcattatt atttaaaact aaagaagaat ggagataacg
     9841 atttccgtta tacagttaga gaaaatggtg tcgtttataa tgaaacaact aataaaccta
     9901 caaattatac tataaatgat aagtatgaag ttttggaggg aggaaagtct ttaacagtcg
     9961 aacaatattc ggttgatttt gatagtggct ctttaagaga aaggcataat ggaaaacagg
    10021 ttcctatgaa tgttttctac aaagattcgt tatttaaagt gactcctact aattatatag
    10081 caatgacaac tagtcagaat agaggagaga gttgggaaca atttaagttg ttgcctccgt
    10141 tcttaggaga aaaacataat ggaacttact tatgtcccgg acaaggttta gcattaaaat
    10201 caagtaacag attgattttt gcaacatata ctagtggaga actaacctat ctcatttctg
    10261 atgatagtgg tcaaacatgg aagaaatcct cagcttcaat tccgtttaaa aatgcaacag
    10321 cagaagcaca aatggttgaa ctgagagatg gtgtgattag aacattcttt agaaccacta
    10381 caggtaagat agcttatatg actagtagag attctggaga aacatggtcg aaagtttcgt
    10441 atattgatgg aatccaacaa acttcatatg gcacacaagt atctgcaatt aaatactctc
    10501 aattaattga tggaaaagaa gcagtcattt tgagtacacc aaattctaga agtggccgta
    10561 agggaggtca attagttgtc ggtttagtca ataaagaaga tgatagtatt gattggaaat
    10621 accactatga tattgatttg ccttcgtatg gttatgccta ttctgcgatt acagaattgc
    10681 caaatcatca cataggtgta ctgtttgaaa aatatgattc gtggtcgaga aatgaattgc
    10741 atttaagcaa tgtagttcag tatatagatt tggaaattaa tgatttaaca aaataaagga
    10801 gaaaaacatg gttaaatacg gtgttgttgg agcagggtat tttggagctg aattggctcg
    10861 ctacatgcaa aagaatgatg gagcagagat tactcttctc tatgatccag ataatgcaga
    10921 ggcgattgca gaagaattgg gggcaaaagt agcaagttcc ttagatgagt tggtttctag
    10981 cgatgaagta gattgtgtta tcgtcgcaac tccaaataat cttcataagg aaccggttat
    11041 taaggctgca cagcatggta aaaatgtttt ctgtgaaaaa ccaattgcgc tttcttatca
    11101 agattgtcgc gagatggtag atgcgtgtaa agaaaacaat gtaaccttta tggcaggaca
    11161 tattatgaat ttctttaatg gtgttcatca tgcaaaagaa ctcattaatc aaggagttat
    11221 cggagacgtt ctatattgtc atacagctcg taatggttgg gaagaacaac aaccgtcagt
    11281 atcatggaaa aaaattcgtg aaaaatcagg tggtcacttg tatcaccaca tccatgaatt
    11341 ggattgcgtt caattcctta tggggggcat gcctgaaact gtaaccatga caggtggaaa
    11401 tgtggcccat gaaggtgaac atttcggtga tgaagatgat atgatttttg tcaatatgga
    11461 attttctaat aagcgttttg ccttgttaga atggggttca gcttatcgtt ggggtgaaca
    11521 ttatgtctta atccaaggaa gcaaaggtgc catccgctta gacttattca actgtaaagg
    11581 aactcttaag ctagatgggc aagaaagcta tttcttgatt cacgaatcgc aagaagaaga
    11641 tgatgatcgg actcgtatct atcatagtac agagatggat ggagcaattg cttatggtaa
    11701 accaggtaaa cgtactccat tatggctatc atctgtcatt gataaagaaa tgcgctatct
    11761 gcatgagatt atggaaggag ctccagtatc agaagaattt gcaaaacttt tgacaggtga
    11821 agctgcccta gaagcaattg ctactgcaga tgcttgtacc cagtctatgt ttgaagatcg
    11881 caaagtaaaa ttgtcagaaa ttgtaaaata aattttggta ttctcctatt ataggtcgac
    11941 ttgctcctct gaaagtactt ttagaggagc tgtttgactt tgctagtttt tgaaactgaa
    12001 atctattata ctacaaacta ttgaaagcgt tttaatttta aggtataata atctcataga
    12061 aataaagaaa aggaggaaag aggatg
//
LOCUS       DAVBNZ010000059        12027 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000059 DAVBNZ010000000
VERSION     DAVBNZ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12027
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.059"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(<1..207)
                     /locus_tag="VQ860_001766"
     CDS             complement(<1..207)
                     /locus_tag="VQ860_001766"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120155.1"
                     /translation="MENMTNHLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFF"
     gene            complement(275..916)
                     /locus_tag="VQ860_001767"
     CDS             complement(275..916)
                     /locus_tag="VQ860_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3120156.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(918..2947)
                     /locus_tag="VQ860_001768"
                     /pseudo
     CDS             complement(918..2947)
                     /locus_tag="VQ860_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(3216..4115)
                     /locus_tag="VQ860_001769"
     CDS             complement(3216..4115)
                     /locus_tag="VQ860_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3120157.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ860_001770"
     CDS             complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ860_001770"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET3120158.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(4747..5520)
                     /locus_tag="VQ860_001771"
     CDS             complement(4747..5520)
                     /locus_tag="VQ860_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET3120159.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKNLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(5825..6718)
                     /locus_tag="VQ860_001772"
     CDS             complement(5825..6718)
                     /locus_tag="VQ860_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET3120160.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLETTPGGDKGGNTGRSDANANAGGGSQAGGPVHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVAVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(7002..7136)
                     /gene="rpmH"
                     /locus_tag="VQ860_001773"
     CDS             complement(7002..7136)
                     /gene="rpmH"
                     /locus_tag="VQ860_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET3120161.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(7281..8495)
                     /locus_tag="VQ860_001774"
     CDS             complement(7281..8495)
                     /locus_tag="VQ860_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3120162.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLGIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(8651..8944)
                     /locus_tag="VQ860_001775"
     CDS             complement(8651..8944)
                     /locus_tag="VQ860_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120163.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLIYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            9106..9558
                     /locus_tag="VQ860_001776"
     CDS             9106..9558
                     /locus_tag="VQ860_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET3120164.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIVHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(9593..10981)
                     /locus_tag="VQ860_001777"
     CDS             complement(9593..10981)
                     /locus_tag="VQ860_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3120165.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            11047..12009
                     /locus_tag="VQ860_001778"
     CDS             11047..12009
                     /locus_tag="VQ860_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET3120166.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT         3435 a         2823 c         2193 g         3576 t
ORIGIN      
        1 aaaaaaatca gcttcttgat aacttcgatt ttcgggtagg gtcaaatcca catcctcctc
       61 cacatcatcc actgtcagtt caaccgtttg aggtaaattt ttcaaacgat aatgcttttg
      121 cctttgccct tcactactag caaaatcaag caaatagcca tgcactcgga tttgaaccaa
      181 aaggagatga ttggtcatat tttccatgat gaggatatct tataaaccac ctctggcact
      241 aggataatca gataccctgc gaatacggat tttttcacac atgagcaagt ttcctcatat
      301 caatgatttc atcagcctta ttccagacta ggggattatg ggtcgcaatg atgataattc
      361 gattttcatc tttcaaatcc accaagagat tcataacctc ctctgaattt tcaggatcaa
      421 gagctgctgt tggttcatct gccaaaatca agggtggatt tttcaaaata gttttcgcaa
      481 gggcaactcg ttgggcctct cccccagata aagtataaat tttttgttct aaatccaaat
      541 accctagatt aactttttct aaagccccca cttgcctttc caaacgttct acttttgaga
      601 ttttctgacc aacaaaaccc aaatccaaat tttctttgat tgattggttt tctaagaggc
      661 caaaattttg aaagagatag cccatctgat ctcgaaaata ctcacgagtg ggaatggttt
      721 ttaaatcttt cccctgatag agaacccttc ctccatctat cttttctagc tttcccaaga
      781 tattcagcag cgtcgtcttt ccgcttccac tctttccgat taaggcataa accttgccct
      841 tctccagctt gagattcaaa ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc
      901 cttgaatatc aatcatctta ttttcctttc aatactgcca tgctaccagc ttcttctttt
      961 ttgtcctgcc ttactaaaat caagagggcg ttaagcgtaa acaaagctac aactagagcg
     1021 ctaatcaaac catctcttgt caaaatacta gataggacta ggccaagcaa gagaactcct
     1081 ccttgcgcca gtaaatactt gccatgaagc tcatagattg tcataccagc aagacgttta
     1141 atcataagct cccgtctgaa ctgctcaaaa tagagaagat tcatggaatc aaataacaag
     1201 atagccgtag acagggtcaa aatcgtccca ataaggagag agtaaaactc tacccgtttg
     1261 tcatttagta ccttggcaaa aatagctggc tttttaccaa gtaagaaacc ttgtgataca
     1321 gaccttgctc ttttagagct gtgatgctgt ctccatatcg atctagtttc aaggcactat
     1381 tagccgtagt tccccacaac atccctgcaa caggtcttgt tccagtcgct tgcggcgtta
     1441 gaactacaat aatcggatct tttaggtact ggcgtgttgt cttgtaccca tcattataga
     1501 ggaaacgttc ctgtcctgtt tctgtaaaag ctagacttac ctgtgggagg tagtatttct
     1561 gactcgtcac ttctacactt tcagatgaaa agttttgcag gtaatctgta aacaatcctt
     1621 ggtagtaggc agactgctct cgcaagctct caggcaagat cagcccaaac tctccctcag
     1681 acaagttttg catcttgtcc ataaactctg aagaaacggt aatcttttct tctatcagat
     1741 agcgtggtga gacatagata acattccctg acggtgtgta gtcactgaga cgattgccat
     1801 ctaggtccac ttctgctccg tctgagaaat tgtcaacatt gctcataata taaaaagagt
     1861 ctgtattggc taaccgttct tcagtaaatg tctgccactc acgattatcc ttacgcgttc
     1921 cttcttcatc ggcaaatgca ctagaccaac caaaggatag acggtaacgg tctgaggact
     1981 ggctccattt attgctagct ctctccattt cctgcatttc acggtagtgg ggtaggagag
     2041 ctgtcgcact cgatccgacc accaatacag ctaagagttg ccccaccatc atcaatgtca
     2101 tcatacgttt gagagggagt ttccctttca atagatccac cagactattt tcctgtaaac
     2161 caagtagata gacgacactt agtaaggtag aaatccctgc cagggtcaat ccataaagta
     2221 gaagagcaat gatgaccagt tgcaccgttg ccataaacaa gacaccttga taccagagaa
     2281 tccccaatcc caaaagactg gataccagca ctgagtagat aaactgtctc acatcttcta
     2341 acactggtct gagagcaact ccaaacaagc tctcaccagc tattaagcga atccctgcct
     2401 gacgaaggga tttgatccga taaatcaggg tcagactcat aaaggtcagc agaaaaatag
     2461 ctaaactcag tagcaccata ggggtggccg ccaatagtaa gactatcgaa aatggatctt
     2521 ctccattcga aacaaagcct tgatagccaa gttctttcaa ggtggtctgt aagctcactc
     2581 catccaaact tcctgacaca atcaagtaag accctaataa atcactcgtt tctgcactct
     2641 ccttggagga aatggtcaga ccttctggaa gctctccctc accataagtg gcataggtaa
     2701 agagtgtttc tccagcttca tttggctcaa cgattcgacg ggcgatgaga ctattatgct
     2761 ctaccgccaa gtgactcaaa acctctgtca cctcttcgcg actagctact ggttgattta
     2821 tcatcattcc tgtcacatca acagaaggat agttaccaaa taaaatctct tctcgatggt
     2881 caacggaagt tatcaccata taaagcgata ccaataccat tgaaatcaaa ataaataaac
     2941 gtttcatcat ttcctccaaa aagttacttg gtcacttagt gagaaggtga ccacagtcac
     3001 tgcgatgtta agaagcttat taagttcttt ctactagcaa catcttcaaa tacattatat
     3061 ccgttttttc aagaactatc aaggacatca atgtccttaa aatctaacca tttcgtgtca
     3121 tttttagctt atatctaaaa aaacagccct aaagacgaac tttagaactg ttttgatgcg
     3181 agaacaagga catttttgtc actgattcac tatgtttata aatatttttt gacatcctct
     3241 tgccattcct ctgtcaattt ctttactaga aattcatctc caattagctg cgcaaatgtt
     3301 ttagaagact gataaaatga ttcagctaaa ctaaaatctc tttcttctct taatgcttgc
     3361 ttccacaaaa acataaatac aagaggtttc ttttgataat cttgagtttt atccataatt
     3421 tcttgtaaac acgatagata atcattaaaa caatcagtta ctcctacctt ttcaagacaa
     3481 cacattcctg aaataagagt atctctaatt ataaagaagt tttctaattt agttaccttt
     3541 ttctgttcca aaagaaagag cattagcttt tcgatttgat ttataaattt ggcaagatct
     3601 tttctaatga gcatttgata aaaaaacaaa cgaatcaaca acatatcatt tgttgaataa
     3661 acttcttttt ctatgatctg aggcatatgt tcctcaagta ttaactctgc atattcaggc
     3721 cttctagttc tagaagtatc caaacacgcc tgcaatactt cacatgctaa ttgttcttct
     3781 ttaggaagat tatcaaagta tgttttataa atctcttcca aacacgcttc cttcttatcg
     3841 tactcctctt ctttaccata gattggttca cgtaaaatct ggtatttcaa ttctaaataa
     3901 gcaggaggaa gagctgaaaa atccggcata aggctataaa ctggaactcc tagccggcga
     3961 gcaatatagt ctaacttggg caaactcggt tgcgaagctc cactttcaat tcgcgacagt
     4021 tgacgaactg tcagttcttg ctcatctcca caaaaatctg gacgactaat tcctttttct
     4081 atccgaatct ctttaatttt ttgaccaatt aacatcagac gcctcctctt ctacctgctt
     4141 cgaaaaatac tgtgaaactt aaaaaattgt aacggctaca tctttcctac tcataagatt
     4201 tcatagcttc ttccacttct gccaaagtaa ccccaaacaa ctctaggcgt ttgaggagtt
     4261 gcttgccgtt ggaatagccg attcggagag tctctccgag atattctcta cgcttacggc
     4321 tgtctgcccc tgctagaaaa ccaaggcgaa tcaaatcgct acgactaatg tcaaactgac
     4381 tctcatgttc aaattgttct gtcacctgag ctagagccgt tttcaggtct tcatagctgg
     4441 catgctcaat tcccagagaa cgccccttgg tcttggactt gggaacagct tcatctcgct
     4501 tgagaaaggc atgctgaact gttggaatga ccgtcatgat catgcgccga atccgttccc
     4561 cattaaaatc tgggtctgta aagacaatga ctccatgacg ttggtgcagg cgctgaatcc
     4621 gctctatatc ctgatcattg atggcagaac ctcgagtctc ataggtctcc acatcgaaat
     4681 aacgcttgag attgaccgta tcatcacgcc cttcaaccac aattacttgg gaaattttct
     4741 ctttcattac ttgctgtcca atccaaaaat gcgttctgca tttgcagtcg ttgccgccgc
     4801 tagctcttct gtcgtcatac cacgcaagtc agcgataaag tcgaccacat agcgagtata
     4861 ggctgtttta ttttcacggc cacgcttggg tacaggtgct aagtaaggcg catctgtttc
     4921 caccaacatc ttgtccaaag gtaactcttt agctgcttct tggaggtcag ttgccttctt
     4981 gaaagtcacc actcctgaga aggaaatggt cataccaaga tccacaaact tctctgccca
     5041 ctcaagcgtc cctgaaaatg aatgcatgat accaccacga ggaccaacgc cctcactctt
     5101 gataatctca taggtatctt ccagcgcatc acgggtatgg acaacaaaag gcaaatccaa
     5161 gttcttagat agctgaatct gacggcgaaa aacctgctcc tgcacctctt tgggcgctgt
     5221 catccaatgg tagtctaagc caatttcacc taaagccaca accttggaat gttttaactt
     5281 atccaacaag taagcctcaa cttcctctgt ataagtacca gcttctgtag gatgccaacc
     5341 aatagtcgca tagagctgct catactcatc taccaactcc aaggcatgct caatcgtcgg
     5401 tttatcaaaa ccaacaatat tcatctgtgt cacacccatc tcagcagcca aggcaatttc
     5461 ttctgcctca cgacctgcaa attcttctac attcaagtgt gtatgtgtat caaaaatcat
     5521 ctcttctaac ctcgttttct atcttctatt ataccaaaaa agaggagggg cacctaattt
     5581 ttcggtttcc cctcctctct tcaataaaga gctattctgc tatcttttct atccgatatt
     5641 gcccatctcc tattccacag ttagagacag aagagattgg ctacattgat agaatattcc
     5701 tattcagcta aagtatgtga ttatcttggg ttctcacttt tctcacccat cactaggatt
     5761 gatgacttct caaaatcccc cttataatct aactttaagt agagaataga attttctagc
     5821 tgttctattt tctacgtcta gtctttcttc ctagcaaagc aaaaccactt gttgccacca
     5881 ctagaccaag actagcaagt gctgcacttg atgctgaacc tgtgttaggt aattgtttgc
     5941 cagcaggtga ctggtaggta acatcttgca ttgttcctgc agttgcttgc ggtgcacttg
     6001 ttgtcttagg agcagcatta ggagccactg gtctcttagg aactgcaacc atggcaatgg
     6061 cttgcactcc aatcgtttct gcttccttca catcttccat agttttcgca ttttcaatct
     6121 ctttgagagc tgcttgtttt tctgcttcca ctcttgctaa aagttctgct ttttctttat
     6181 cagaaagcgg tgcgcctttg atttcatcct gcttgttctt ggctgctttt tcaatggcat
     6241 ttttagctga ttctttttca gtagctaatt gcttagaagc ttgtgattga gctgagtttt
     6301 gtgaacctgt gtgaactggt ccacctgcct ggctaccacc gcctgcattc gcattagcat
     6361 ctgatcttcc agtattgcct cccttatctc cacctggtgt agtttctagc ttatactctg
     6421 gtgtagcttc ttgagttaca gattcacctt tcgcagattg ttgaactgta tcttttccta
     6481 gaatcgtcac tactgaacca tctgggaatg tgattgttgc tgtaccatct ccagctacat
     6541 tgattgtcgc tccgtctaat gctgaaccat ttgcttgtaa aatagcaacc ttaacttttt
     6601 cttcatctgt taaatgagtt atatctttta catctactct ttgagcaggt gctttaacag
     6661 ttgatttttc agcagtcggt ttagtactat cttgtgcttt tggatcttgt gctaccaatt
     6721 gatttcctgg aattgtaata gctgaaccat ctttaaagac gattgtcgct gtaccatctc
     6781 cagctacttc aactttatag taaaataaaa taataacagg acaaatcgat caggacagtc
     6841 aaatcgattt ctaacaatgt tttagaaaca gaggtgtact attctagttt caatctacta
     6901 taacatcgct tccgaatcca tttgcatcta ctgaactttt ttacaaaaat aaaaatcagt
     6961 agactcgagt tcctactgat ttttgataga attcgtttgg attatgcagc caaaactttg
     7021 cgtcctttac gacgacgagc tgccaatacg cgacgaccat ttttagttga catacggtta
     7081 cggaatccgt gtttgcgcgc acgacgaagt ttacttggtt gataagtacg tttcacgatg
     7141 aatacctcct catagatttt gtattcgttt agccggctat aaagtgatca gttactaaac
     7201 atactttact attctatctg attctttcac ttttgtcaat agctctaggc aaatgtttcc
     7261 agctttttcg aatgcaagcc ctatctacga tactgtttca agaaacgagt catcttttct
     7321 tggatttggg ctaactcatc aacacgagga aggtaaacga tacggaagtg gtctggttcc
     7381 tgccagttaa agcctcgacc atgaaccaag agaacctttt cctgcttcaa gaaatcaagg
     7441 acaaactgct catcatcatc gatacggtac atattgcggt cgatttttgg gaagatatag
     7501 agccccgcct tgggtttaac ggcagacaaa cctggaatat cttgaatggc attatagatg
     7561 aaatttcttt gctcgtagat tcgtccacca ggaagaagca attcatcgac tgattggtga
     7621 ccccccaagg aagtttgtac gacttgttgg gccaaaacgt tagagcaaag gcgcatattg
     7681 gacagcatat tgagcccttc gatatagccc ttaacatgag tcttagggcc agacaagacc
     7741 atccaaccca cacggaaacc tgctatgcgg tgggattttg acagaccatt catgctgaca
     7801 cagaagacat ctggtgccaa gctcgccaca ggcgtatgca catgtccgtc cattaccatg
     7861 cggtcataga tttcatccgc aaagataatc aaatcgtttt gacgggcaat ctcaataatc
     7921 cccagcaaga gttccttagg ataaagggct ccagttgggt tatttggatt gataaggaca
     7981 attgccttgg tattggaagt gatttttgac ttgatatcgt caatatctgg gtaccattcc
     8041 acagcttcat cacagatata gtgaacggca tttcctccag ctaggctgac agccgccgtc
     8101 catagaggat agtctggcat tggcactaag acctcatccc cattgtccaa aagcccctgc
     8161 atggacatga caatcaactc actgacacca tttccaaggt aaatatcatc aatatctacg
     8221 tttgggaatt tcttcagctg gcaatactgc atgatggcct tacgggctga gaaaatccct
     8281 ttggagtcag aatagccttc actatcacgc gcattcataa tcaagtcatg aatgacctcg
     8341 tctggcgctg taaagccaaa ttctgctgga tttcctgtat tcagacgtaa aatcttttct
     8401 ccattcgctc gcatccgcat ggcttcttcc aatacaggac cacggatatc ataagcaaca
     8461 tgctctaact tactagactt gttatattct ttcatcttgt ttcctcaatt catcaggata
     8521 gtaacattat accactagaa agagaatgcg acaagtttac tgaaatgtgt tactagtttc
     8581 gtatagaaga aaaaccttgc taaaggcgag gttaagaacg tagagatagc aggtattttg
     8641 caaagacaca tcacatacca aaagataaac ctagaaaaag caagcctaga aaggagtcat
     8701 aaagaagatt aaacatgagg aaaagccccc atatcatcaa gtaatcccaa cgcccacttc
     8761 gttttgcaac tagaaataag attagatggt agagtacatg aaagactaaa aatccaataa
     8821 aacctggata aataagcggt accaaactct ctaattgcca gatcatgatc acttctacca
     8881 agactgaaac taggataatt ccataataca ggaaatttga tttttgaaaa gagtttttca
     8941 tcattctccc ttccttcact tctttcctgc tatcctttct tttattttat catatattta
     9001 tatagatttt aagccctaat attcttttga aaaatacttt ttttgcttta cttctatagt
     9061 gaaaaggttt acaattatag taagaaaatt tcaggaggtt tcattatggc acaacgttac
     9121 caaaatatca tggtcgcaat cgatggttct aaggaagcgg acttggcttt tgtcaaggga
     9181 gttcattctg ctctacgaaa cgacgctaaa ctcaccatcg tacatgtcat tgacacacgc
     9241 gctctccaaa gcgtatccac ctttgatgct gaagtttacg aagaactcca agtcgacgct
     9301 gaaagtctga tgaaagagta cgaaaaacgt gctaaagatg ctggggtagc agatgttcat
     9361 atcgtcattg aaatgggaaa tccaaagacc ctgctagcac gtactattcc agatgccgag
     9421 gaagtggacc tcatcctcgt tggcgcaact ggtctcaacg cctttgaacg cctcttagtc
     9481 ggctcttcat ctgaatacat actccgccat gctaaggtcg atttgctggt tgtgagagaa
     9541 caagaaaaaa ccttataatc acaaagaaaa ggagccccta gctccttttt gtttacgatt
     9601 tatttctctc tttatggcgt tcgtaagcct tgagctggcg ctgcagttcc tttttaatag
     9661 caggttctgg agcatatttt tcttcccaat tatctggttt taagatttta tgggtcactg
     9721 gatcaaaatg agccttgcca tctggaaaaa ttttccccat attggcctga tggacaatat
     9781 caaaaatacg ttctgggtcc acccccatca agacaaaact gccgtaggtg aagtaaagcg
     9841 tgtcaatcaa ggcatccact tgccctatca aatcttgctg agcaggtgtc ttcttggcta
     9901 ctttacctgc tgccttatca agggcctgat gaagttgcga tacagcttga ccaaaatctt
     9961 cttcagaagg actggctgct cgaacaaact ccaccaattc ttctatttta aaaccagccc
    10021 tatgggttgc accctctaaa tcccaagctc gaggttcttc ttgggttcgt tcatccatca
    10081 tgtggtggaa ggtcttgacc ttattgaaat gatagtcacg gctgacaaag actttttctg
    10141 aagacaaaac accaaaatgt tccaaggcct tgtggatccc atcttgttga ttgctagtgg
    10201 taatgtgctt ggcagcttcc ttgacactgc tactaccatt tcccatagcg accgacatac
    10261 cgacgccagc cagcatttca aggtcattat ctgagtcacc aaaagccatg acttggttga
    10321 ggtcaaagcc atattctttc ccaactcggc gaatgccttc taatttagaa tttccctgat
    10381 tgatgacatc cgatgcaaaa ggattgctac gtgtcaattt caagtcttca aaatcagctg
    10441 ccgccttctc agattcttct ggtgtcatca gcatcaaaac ttggtagata ggctgattca
    10501 tcaggtgaag caggtcctct tccttttggg gaacaacctt gctgaccatg cgattaaaag
    10561 actgactcac cgtccgagtt aaaacagagg gaacgaagcg actaattcgt tgggaaaaag
    10621 aacccagacc aaaggacatg attttagaac ccaacatggc atccttggtc cctagagcaa
    10681 tctccgtgcc ctctttttta gcatagctaa ttagatggcg caaatgtaac ttggaaatag
    10741 ggctcgtgaa caagactctg tctttactaa agatatactg gccattatag gttaccgcaa
    10801 aatccagatc caaatcgtcc atcaattcct taacaaaaaa aggtcctcgt cctgtcgcta
    10861 cgccaactag taccccttgt tctttgacaa tcttaatcgc gtccttagtg gatttcaaaa
    10921 cactcttgcg attgttgacc aaggttccat cgatatcaaa aaaaacagct ttgacttcca
    10981 tcctattcca atctcccctt ttgtgataca atgattatac cacatttcag aaagagttag
    11041 taaatcatgc ctaagaaaat ccttgtttta catacgggtg gaactatttc catgcaggcc
    11101 gatgcttctg gcgctgttgt gacgagttca gataatccca tgaaccatgt gtccaaccca
    11161 cttgaaggaa tccaagtcca cgccttggac ttttttaacc ttccaagtcc ccatatcaaa
    11221 cccaaacata tgctggtcct ctaccagaaa attaaagagg aagcagataa ctacgatgga
    11281 gtggtgatca cacacggaac cgatacttta gaggaaacag cctatttcct tgataccatg
    11341 gaagttcccc atatgcctat cgttctaaca ggagccatgc gtagctccaa tgagctcggt
    11401 agtgatggtg tttataatta cctaagtgct ttacgagtgg ccagcgatga cagggctgct
    11461 gacaaaggag ttttggtcgt tatgaacgat gaaatccacg ctgccaagta tgtcaccaaa
    11521 acacatacga ctaatgtcag caccttccag actccaacac atggccccct cggtctcatc
    11581 atgaaacagg aaatcctcta cttcaaaaca gctgaacctc gtgttcgctt tgaccttgat
    11641 cacatacaag gtttagtccc tatcatctcg gcttatgctg gtatgacaga tgagctgatt
    11701 gatatgctgg atttagaaca cttggacggt ttgattatcc aagccttcgg agctggtaat
    11761 attcccaaag aaacggctca aaaattagaa agccttctgc aaaaaggaat cccagtcgct
    11821 ctggtatcac gatgctttaa cggtattgcc gagcctgttt atgcctacca gggtgggggc
    11881 gtacagttgc aaaaagcagg cgttttcttt gttaaagaac tcaacgccca aaaagctcgc
    11941 ttgaaactcc tcatcgccct caatgccgga ctaacaggac aggctttgaa agactatatg
    12001 gaaggctaat actcttcgaa aatctct
//
LOCUS       DAVBNZ010000060        11716 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000060 DAVBNZ010000000
VERSION     DAVBNZ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.060"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ860_001779"
     CDS             complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ860_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET3120167.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ860_001780"
     CDS             complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ860_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET3120168.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2411..2905)
                     /locus_tag="VQ860_001781"
     CDS             complement(2411..2905)
                     /locus_tag="VQ860_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3120169.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2902..3366)
                     /locus_tag="VQ860_001782"
     CDS             complement(2902..3366)
                     /locus_tag="VQ860_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3120170.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3376..4710)
                     /locus_tag="VQ860_001783"
     CDS             complement(3376..4710)
                     /locus_tag="VQ860_001783"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET3120171.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLIRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4721..5338)
                     /locus_tag="VQ860_001784"
     CDS             complement(4721..5338)
                     /locus_tag="VQ860_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3120172.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5386..8484)
                     /locus_tag="VQ860_001785"
     CDS             complement(5386..8484)
                     /locus_tag="VQ860_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3120173.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELSDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLSGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8577..9743)
                     /locus_tag="VQ860_001786"
     CDS             complement(8577..9743)
                     /locus_tag="VQ860_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3120174.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(9751..10845)
                     /locus_tag="VQ860_001787"
     CDS             complement(9751..10845)
                     /locus_tag="VQ860_001787"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3120175.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(11003..11656)
                     /locus_tag="VQ860_001788"
     CDS             complement(11003..11656)
                     /locus_tag="VQ860_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3120176.1"
                     /translation="MFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYD
                     FNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMK
                     EGLDTEVGERGRLLSGGQSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYS
                     VLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
BASE COUNT         3252 a         2680 c         2220 g         3564 t
ORIGIN      
        1 aagtcagtaa ccatacatac ggcaaggcga cgctgacgtg gtttgaagag attttcgaag
       61 agtagcaaaa tggaaaaagg agtgagtgaa gcacatcgcc tccccactcc tttttctgtt
      121 tttaggctgt tttttcaacc ttcaagattt ttacatcata gctaccaaca ggcgtttcaa
      181 tggttgctgt atcacctgtt ttcttgccaa tcaaggcctg cccaattggg ctttcatttg
      241 aaaccttacc tgcaaaggca tccgcaccag ctgaacctac gataatataa acttcttctt
      301 cgtcctcacc aatttcttgg atggtgactg ttttaccaat cgctacttcg tcctgggcaa
      361 ctgcgtcgct attgacgatt tcagcatagc ggatttttgt ttctaagcta gagatttgtc
      421 cttcgacaaa ggcttgttca tccttagctg cttcgtactc actgttttct gaaagatcac
      481 cgtatgaacg ggcaatctta atgcgttcta ccacttctgg tcgacgaacc aatttcaatt
      541 cttctaattc tttttcaagt ttctcctttt cctcaagggt cataggatat gttttttctg
      601 ccatttttct caactttctt ctgataatat tttctaaaga aaattatgtg aagtatcaca
      661 taattttagt ttgtttagtt taatttgctg ttgacatgtt cagcgacatt gcggtcgtgg
      721 tcttcttgat tgttagcata gtagaccttg ccttctgtga catctgctac aaagtagagg
      781 ttatcgctct tagtttgatt gatgcttgac tcaatcgcat ccagacttgg actatcgact
      841 ggaccaggca tgagacctac atttttataa acattataag gtgaatcaat gtcggtatca
      901 atcgcaacat cctcagctag actgatattt tgccccagtt ttccttgggc atacaagatt
      961 gcaatattac tttgaagtgg catatcacga tttaaacgat tgtagaatac acctgcaatg
     1021 agcttacgat cttctgtctt ggcaccttct ttttcgacca aggaagcaat ggtcaacaac
     1081 tcattgatag tcaagttttt agatttgata gtactatagt aaggagatag gttcttatcc
     1141 atagcagcta acatctcatc aatcaagctc tcaatagttg tgctttcctt gatagagtat
     1201 gtagctggga aaaggtatcc ttccaaacga taacgcgcac cgctgtcttt tacaggcaaa
     1261 ctttccagta aagtaggata tttcgctact gcttgactga taaacgtctc atcttgaact
     1321 ttagccaaga aagcctccgc tgtcaaagac tctttgaagt caccttgcaa ttgacccaca
     1381 gtttgagcaa tctgatccaa ggtataacct tctggaattg tcaaagtcgc aagtacaggt
     1441 tcttgcggtt catctgttcc acctttttgc aactctttga gtaagtcttc tgtactcata
     1501 ctcttttgca aattgtagta acctgctttc aagtcggtat aatttttata cttggcataa
     1561 aaactaaaaa tcagaccatg ctttaccaaa ccagcttttt caagcgtcgt accgatttct
     1621 tgaacgtttg aaccttctgg aattccaacc gtcacatatt tcttagaatt agcatcgata
     1681 ggtaacaaag aatctagcac gtactggtaa ccaaagtaac cacctgctga gagcaaggca
     1741 aggaatacaa ggaatgaaat cacaaaagct ttcacatgtg acttcttctc tttcttaggt
     1801 ttaacgggtt ttgctccttc tctacggcta cgacgtgatg tatcgctgat gatatccact
     1861 gtttctgtag caggcgtagg tgtttctgga cctgcttgtt ctgctttttt ctctgccgtc
     1921 gtataggaaa cagctaccct tgttggggtt tcattgtatt ctctttcaag tttcttaggt
     1981 ctaacaggac ctggacctgg tcttgatcca ctttcttccg ctggagaaga aggtacatct
     2041 tgacttggat gacttggaac accaggagtt tctctttgaa tctcatctgc tggagaagct
     2101 ggtacacctt gacttgggtg agtaggcacg gtaggagctt ttctcataat ctcctctacc
     2161 gttgacaagg aatcagccat gagttcttca gctgaaggtt catttgcagg agtgcgaact
     2221 actgcctcat cttctttcag aacttcatca tagcctttta ctttttctaa atctctcaga
     2281 atctgctctt taaagcttaa tttctcttct tctcttgact tttcactcaa aagtttttcc
     2341 tccttgttga taatccataa tattatatct taaaagtcca aaaaaagcaa tctatgatac
     2401 ttttcctaac ttattttttc atttcccaga ccatatcata ccatgtttcc cctgcaaagg
     2461 ttgactggga ctggccttcg ttgacaaatc catgtttttc ataataggcg atgagatagt
     2521 catgacaggt tagattaatg ccatctctct catcttcaag agcaacttct ttcaaggctg
     2581 tcagcaattt ctgacccagt ccgagtccct gtgcctcctt ggcaatagac agacaggtca
     2641 cagagatata accaccaggc tcatgactat agtcttttat ttcttctgta aaagactggt
     2701 cttgcagatg gcggtgcagg ccaactggtc cttcgatata acccatgatt cttccttctt
     2761 tttcagcaac cagaaaagag gtctgaattt ctctcaaatg tgcttcaaag acagaaggag
     2821 gaatggcttc ttcgaccgaa aaattttcaa attcaagttc aacaatccga tccaaatctt
     2881 ctaatcttgc ttgtctgatt ttcattgttc ctccagataa aagggattaa accaaatcat
     2941 actatagccc tggctagttg catagagcaa agttgcttct tcatcaacaa aaccgttcat
     3001 ttcaaaatag gaaagcagct catcaggact ctccaaacga atccctttgt aatccagatc
     3061 aactgccacc tctttcaagg ctgcaagaag aagtgttccc aagccctgtc tctgatggtc
     3121 agactcgatg actaaagaat gtacttttag atattgcgga ttgtctgact ggggacttga
     3181 taaaatatag cctaaaagtt gattttcatc cctagctaga agaaaggtat ccgcacactt
     3241 acggatactt tcttctaaaa tatgggaaag ttgctgcttt tcagctggaa aagacgaggt
     3301 ctgaagtgcc cctatctcag gcaaatcaga cttgcttgcc tgaatgatct taattggaat
     3361 ttccatggga acatcctatt gaacattgct tgtcaagtta gacaagagac gctcaaatga
     3421 gtattcatag gtttggatgt ctcctgctcc cataaagacg taaacagcat tgtcatggtc
     3481 taggagcgga gaaacatttt caacagtaat cacttggtgt tttttgttga ttttgttggc
     3541 taggtcttct accttaacgt caccatgatc tacttcacga gccgagccat aaatttgcgc
     3601 tagataaaca gcatctgctt ggtttaaagc atgggcaaag tcgtccaaca aggcaatggt
     3661 tcttgtaaag gtatgcggtt gaaagactgc tacaatttcc ttgcttgggt atttctgacg
     3721 agccgcatcc aaggtcgcaa taatttctgt tggatgatgg gcaaagtcat cgataatcac
     3781 tgtatcattg acaattttct cagtgaaacg acgtttaaca ccggaaaatg ttttcaagtg
     3841 ctcacgcacc aagttcaaat caaatcctgc tgtgtaaaga agaccaataa cggctgtcgc
     3901 attcatgata ttgtgacgac caaaggttgg aatgtggaat tgccccaagt tttgtccacg
     3961 gaaatgaacg gtgaaggttg aaccagttgt tgaacgaata agatcactag ctacaaagtc
     4021 attgccttca gcttcaaaac cataataata aattggtgca tcagacgtaa tcttacgcaa
     4081 ttcagcatct tcaccataga caaaaagacc cttggtgatt tgtttggcat agtcgttaaa
     4141 ggcattgaaa acatcctcga gacttgtgaa ataatctgga tggtcaaagt caatgttggt
     4201 gataatagag tattctgggt ggtaaggcat gaagtgacgc tcatattcgt cagattcaaa
     4261 gacaaaatat ttggcattgg ccgaaccacg acctgtccca tctccaatca agaagctggt
     4321 atctgtaatg tgagacaaga catgagacaa catacctgtc gttgaagttt ttccatgtgc
     4381 tcctgctact cccatgctaa caaagtcacg cataaagcta cctagaaact catggtaacg
     4441 tttatagctg ataccatttt ggtccgcata ggcaatttcg acgttgttat ctggacgaaa
     4501 ggcatttcca gcgataattt ccatatcacc gtctagattc ttttcatcaa aaggaagaat
     4561 ggtaattcct gcctgctcaa gaccgcgttg ggtaaagtag tacttttcaa catctgatcc
     4621 ctgaaccttg tgccccatct ggtgcaacat caaggccaag gcactcatcc ctgatccctt
     4681 aattccgata aaatgatatg tctttgacat gttttctccc ctattctgtc attctggtca
     4741 gattcaactc ttgggcaacc cgacgttctt gttctgtttg tttacttttt ttattgtaga
     4801 tttggctctt ctttagaaaa tcataattgt ttttctttgg agcaggtgct gacacttctt
     4861 cattcttggt agggatagaa tgaacttctt ccgccaagat ataatgagac tgggtcaatt
     4921 tttggctata tttgacaaat tcaccaggat tttccttttg gaaaggagtt gtcggttgat
     4981 tgccctgtct aactagactg ggctgagaat gacgtctcgc aaggctgaaa tcctgagtta
     5041 gatagttagc agagcgtttc tttttcaagt ctgcacgcgc ttcttcacgc gccacctccg
     5101 catagctctt tccttctttt ttaaccccta aaggagcttt tttaggtttc cctacttgct
     5161 tttcaatcgg ttttactggt ttttcttcag caataggagc ccattctaaa taatttttat
     5221 ctcgatactc acccttgata ttactgatca gatcagactc atcatagaga ttcatgactg
     5281 gcatttcagt caacatgacc tcgtcatctg acaccaatgg aaatcgttct tgtttcattt
     5341 tctatttcct ttcaacactt cattatagcg tattgtcttg atttttcaag tgctggcttc
     5401 agaaattccc aaaatttctc taatttctgc tagggtcaga ctaccacgtg actctgtgcc
     5461 gtccaatact tgtgacacca gatgtttctt ttgttcttgg agttcctgaa ttttttcttc
     5521 aatggttccc ttggtcacca agcgatagac ctcaaccgtt tcttcctgac ccatccgatg
     5581 ggcacggcca atggcttgcg cttccaccgc aggattccac caaaggtcaa ccaagatcac
     5641 tgtatctgca cctgacaggt tcagaccgac cccaccagcc ttgagggaaa tcagaaaggc
     5701 atctctttct ccttgattaa aggccttggt catgtcttgt ctttccttgg ctggggttga
     5761 acccgtaatt ttaaaggaag tcaggcccaa gtctgacagt tcttgttcaa ttttttccaa
     5821 cattcccttg aactgagaga aaatcaagac acggtgtccg ccgtctgcca cctgtaccag
     5881 taggtctcgg agactatcta gtttgccgct ggctccctga taatcttcca taaacagggc
     5941 aggagtgtca catatttgac gcaagcgcat caaaccagat aaaatttcca cacgacttcg
     6001 ctgaaattcc tgttctgaca cttgagccag atggtctcgc atctgttgta actgggcaag
     6061 gtaaatagcc ttttgctggt cttccagttc atttttataa accacctcaa tcaagtctgg
     6121 caattcagtc agaacttctt ctttcttgcg tcgcatcacg aaaggcttga taaactgagc
     6181 cactcgctct gctggcaatt tcataaattc tttcttgctt ggcaaaagtc cgggcatgac
     6241 gatttggaaa atagaccaca actcacccag atggttttca atcggagttc ctgacaaggc
     6301 aaagaccgac ggcaccacaa attgtctcaa ggtctgggca atcttggtct gggcattttt
     6361 catgacctga gcctcatcta agaaaaggaa gtcaaaggcc atcccctgat aaaactcact
     6421 gtcctgacgg aaggtggcat agctagtcac atagatttga tggctctcgg caagaatctc
     6481 ctcacgactt gctttcaaac catgaacaac agccacatcc aactgtgggg caaatttctg
     6541 aaactcatcc gcccagttgt aaatcaaacc cgacggagcg agaatcaaga ctcgactttc
     6601 ttttgtcact tgactagtca aaaaagcaat ggtctgaagg gttttcccaa gtcccatatc
     6661 atcagccaaa atcccaccaa aaccataatg atggagcatc tgcaaccagc caattccctt
     6721 ttcctgataa tctcgcaagt cagccttgac ctgagttgct tgcaaaggaa agtcctctgg
     6781 atgcgtcaaa tcctgggcca gattctggaa ttcttgtgaa aaagaaacac ggtctcgccc
     6841 ttcaaagaga tgagctaaac tgtaggccaa ggatttccga gcctgcaagg tcccatcttt
     6901 taattcaaat tgccccagtt cctgtagatt ttggcgaatt ttcttggttt cttcatcgaa
     6961 aaagtaaact tgattagacg aatcaatata aaaatcctga ttggcaacca aggcctgcat
     7021 ggcttggtcg atttcctcct gggcaatatt ttgaaaatca aactggattt ccaagagacc
     7081 tcccttggag gcaatctgca cctgaggact cgctaggcta taaagctctt ctagtttatc
     7141 tgataggtca acatgcccga gtttttcaaa gactggaatg atatcatgaa aaaaatgata
     7201 gacagactcc gcttttaagg cctgacgcca agattgaaaa tcggcttcaa agcccgcagc
     7261 caaacagact tggaaaattc tttcttctaa gtccgcgtca cttgaaaatg gtaattcttc
     7321 tagctcttgt cggctagata cctgtctatt tccataatca aactgaattt ctaaacgaat
     7381 ccgattatct tcttccctgt caaagtaaaa agagggcgca aaagttttga tttgtagacg
     7441 ttctggagct gaaacggtgc ccatctggat aaaaagagtc agacaggagg ccaatttgtc
     7501 tcgatcactg ctatcaaatt gcaggtattt ctttccttgt tgacccacag gtaacgcttt
     7561 aatttccttg agaagacgca tctgctggtc tgttaaaaaa taaacctgac ctttatggaa
     7621 aagtactgct ccctgataaa agacattgac cctaggactc tcactgattt ccatttcaaa
     7681 atagtccgag tattctgtta ctgtaaaggc aaatagattg gcatcagcat gcatatcctg
     7741 aaaaagcagg gtttggtagc tatccacttg atggtcaaat tgaaaatggg gcaaggccat
     7801 cagtaaattc acaccctgct caaaaaaggt cagagggaaa aagaggtgcc gaccttggtt
     7861 ttggaaaaag aggtctggaa ccagcccttc ctccgttagt ccgtgcaaga aagtcaaaag
     7921 ttcttggctg gcatcatcaa aggcttccca agaaagagac tcctcataaa tcttgccaat
     7981 catatacgac tttctctgct cgacaatcct taaaaaaagt ggaatatccc gaatgacata
     8041 gtatttttgg ctattgattt ggccgattct cagagtccac aagatatgat tggttcctgc
     8101 ttccacctga cccacagctg ataactcata ggcgcattct gattttggag ataaaattcg
     8161 attcaaaaac ttgccaccca aggtcacctt ggtttcaacg gcctcttttt cttcatgacc
     8221 ttcttccaga ctccacaaga tttcctgacc acgctcatca tttttcagaa aatgctctag
     8281 cgctgccaaa tgcacacagt agcccctctt ttgaaaagaa tcacaggcac aaaaaaccaa
     8341 atcatcctct aaactatagc gcagttcttc ttctgcaacg cgagcgtaga gccgattgtt
     8401 cttttccttg atgatatcaa ccttaccagt ttcataaagg gcaacacctt cgatacgaat
     8461 tttccccgga atcaatttag ccatattttc acctttacct tatcttttta ttataccata
     8521 ttttcgccta tgaaaatagc cttctaggaa gacttttctc ctagaaggct ggatttttaa
     8581 cgtttggcaa aagtagccac aatccgctga cagacttctt gcaacagaga tttgggcata
     8641 gctatattga tgcgggcatg gagacttcct tcctctccaa aatccaaacc acggttgagg
     8701 ataaccttgg cttcatttct caacaactct tgcaatgttt catcagtcag gtcataggct
     8761 gaaaagtcaa gccaaatcaa gtaggtacct tgcggtttca tgaccttgat tttagtctct
     8821 tttccaaata gatccaccac ataattgatg tggtcttcaa agacttgctt gagttcctct
     8881 agccaatctt taccgtatcg ataggcagct tctgtcgcca aataacccaa gcctgaaatt
     8941 tcatgctgat tattggccaa caggcgtttc tggaaagcca gtctcaactt aggattttca
     9001 atgactgcat aggaattttt tgttccagca atattaaatg ttttagtggc actgctcaag
     9061 acgatagcaa aatttttgaa ggcaggattg atggtattga aagactggtg tttgtgacca
     9121 aagagggtca aatcttggtg aatctcatcc gaaactaaca aaacaccgtg tttttggcaa
     9181 agttggccaa tcttctccaa cacttctttt tcccaaacac gtccaccagg attgtgaggg
     9241 ttgcaaagaa tatagagttt aacctcctct tccaccaaat ccttttcaag ttggtcaaag
     9301 tcaatctcaa acagaccatc cttttccact aaggaattag taatcaatct acgattattc
     9361 aacttgacac tgcgagcaaa gggtgggtag acaggcgtgt taattaaaac cgcctcgcct
     9421 tcttttgtaa aggtttgaat agctgttgag atggctggta ccacaccctc gataaagaca
     9481 agagcctctt tgtcaaagtt gtaaccgtat tgtgtagctt cccacttttg aatttcctta
     9541 attaagtctt cactggcata ggtataacca taaaccagtt ggtctgcgta agtttgcacg
     9601 gcttggcgga tttcaggcaa gaccacaaag tccatatccg ctatccaagc tggtagaact
     9661 tcactatccg tttctgtttc tttccattta taggtatggt gccctaaacg gttgggcagg
     9721 cttgtaaaat catattttcc catctttgtc ttatccttct aaggcttggc gcaaatctgc
     9781 aatcaaatct ctagcatcct caatcccaat agacaaacgc aagaggtcat ctgtcaaacc
     9841 ataagaatgg cgtacttctg ctggaatatc agcatgagtt tgagtcgttg gataagtaat
     9901 aagactttcc actccgccca aactttccgc aaaagagaag accttgagac tgttcaaaat
     9961 atgaggaatg cgtgtttcat cggctacttt aaaggaaatc atgcctccac gaccagtgta
    10021 gagaacttcc ttaactgctg gagaatcctt caaaaaggca accacttctt gggcgttagc
    10081 tgttgagcgc tccatacgaa gagataaggt cttgagacca cgaagcaact ggtagctgtc
    10141 aaatggagac aagactgccc ctgttgtatt gagattgtaa aaaagcttct cgtatagttc
    10201 taaactattg gtcacaacca ctccagccaa gacatcattg tggcctgcta gatacttggt
    10261 tgctgaatgg agaacgatat ctgctccatc ttcaatcgga cgttggtaga tagggctata
    10321 gaaggtattg tccaccacca ctttggcacc cttagcatga gccaattttg ctagtttttc
    10381 gatatcaaat tccaacatca agggattggt tggggtttcg atatagagaa catccacatc
    10441 cttttctaac tcggcaatca actcttcttc tgtattggca taggtaaaat ggaaacgacc
    10501 ttcctgctcc acttggttaa accagcgaaa agaaccaccg taaagatcac gcactgccaa
    10561 gaccttactt cctactggaa agacgctaaa ggccagtaca atagctgaca tccctgagct
    10621 agtcgctagg gcatagtctg ctgactcaat agccgccaag acttcctcag ccttactacg
    10681 agttggattt ttagtgcgcg tatagtcaaa cccagtagat cgaccaaact ctggatgctg
    10741 ataggtcgtt gaaaaatgaa gcggtgtcac caatgcacct gtcgcttcat ctgacttaat
    10801 acccgcctgg gccaaaattg tgttaatgtg taattccttg ctcatacaat acctccaaat
    10861 ctatagtaac tattgtacca cttattttca tcaactcatt ttcttctttt caagagctag
    10921 ttatagtttc aaactatata aaaagggagt ttttcctgct ccctttaata gactataaaa
    10981 tggtgaatct caaaagacac cttcactcta tcatttgctc ctgcacaaaa cgagcataac
    11041 gctcatgatt ttccagtagt tccttatgag ttcctgagcc agtgattttc ccctcctcta
    11101 agaagaaaat acaatccaca tcttttaccg ttgacaaacg atgcgctata atcacaaccg
    11161 tcttctcctt taatacagaa tagaggctac tgataatcgc atactcagaa tccgcatcaa
    11221 gattagcagt ggcttcatca aatataagaa tttcagcatc ttttaagtag gctctagcta
    11281 tttgaagtct ttggctttgc ccccctgaca agagtcgtcc gcgttcacca acttcagtat
    11341 ctagtccctc tttcatggag cgaatctcat cacctagtga tactaagtct agcactttca
    11401 tcaattcatc atcagttact aagcgattca aaccgagaca aagattgtca cgaatactgc
    11461 cagataagac tgcattattt tgtgaaaccc aagcgatttt acttctccat tcttttaagt
    11521 taaaatcata tatacttgat tgctccatta gaatatctcc tgaaagcggt ttataaaacc
    11581 gctctaacaa acgcacaatc gttgattttc ctgatccaga tggtccaaca aaagcaattt
    11641 tttgcccctt gaaaattgaa caagtaatat cctttaagac aggtcgattt tcatcataac
    11701 caaaatagac atggtt
//
LOCUS       DAVBNZ010000061        11444 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000061 DAVBNZ010000000
VERSION     DAVBNZ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11444
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.061"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..125
                     /locus_tag="VQ860_001789"
     CDS             <1..125
                     /locus_tag="VQ860_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120177.1"
                     /translation="KASQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
     gene            complement(355..1335)
                     /gene="dusB"
                     /locus_tag="VQ860_001790"
     CDS             complement(355..1335)
                     /gene="dusB"
                     /locus_tag="VQ860_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET3120178.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1322..2194)
                     /gene="hslO"
                     /locus_tag="VQ860_001791"
     CDS             complement(1322..2194)
                     /gene="hslO"
                     /locus_tag="VQ860_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET3120179.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2359..3786
                     /locus_tag="VQ860_001792"
     CDS             2359..3786
                     /locus_tag="VQ860_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3120180.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3945..5453
                     /gene="glpK"
                     /locus_tag="VQ860_001793"
     CDS             3945..5453
                     /gene="glpK"
                     /locus_tag="VQ860_001793"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET3120181.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQMDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEIDD"
     gene            5600..7426
                     /gene="glpO"
                     /locus_tag="VQ860_001794"
     CDS             5600..7426
                     /gene="glpO"
                     /locus_tag="VQ860_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET3120182.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7496..8200
                     /locus_tag="VQ860_001795"
     CDS             7496..8200
                     /locus_tag="VQ860_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3120183.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8497..8700
                     /locus_tag="VQ860_001796"
     CDS             8497..8700
                     /locus_tag="VQ860_001796"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120184.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8787..9047)
                     /locus_tag="VQ860_001797"
     CDS             complement(8787..9047)
                     /locus_tag="VQ860_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120185.1"
                     /translation="MTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(9102..9446)
                     /locus_tag="VQ860_001798"
     CDS             complement(9102..9446)
                     /locus_tag="VQ860_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120186.1"
                     /translation="MSKMFKCMCLLVMSVFCMSSISPSLVVFADDSLSANSKVVSGEA
                     QFENGSSVRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEID
                     LNISFRSYDPNV"
     gene            10486..>11444
                     /gene="ltrA"
                     /locus_tag="VQ860_001799"
     CDS             10486..>11444
                     /gene="ltrA"
                     /locus_tag="VQ860_001799"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET3120187.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLS"
BASE COUNT         3389 a         2225 c         2609 g         3221 t
ORIGIN      
        1 tgaaagcaag ccaatggttc aaagtatcag ataaatggta ctatgtcaat ggctcaggtg
       61 cccttgcagt caacacaact gtagatggct atggagtcaa tgccaatggt gaatgggtaa
      121 actaaaccta atataactag ttaatactga cttcctgtaa gaactcttta aagtattccc
      181 tacaaatacc atatcctttc agtagataat atacccttgt aggaagttta gattaaaaaa
      241 taactctgta atctctagcc ggatttatag cgctagagac tacggagttt ttttgatgag
      301 gaaagaatgg cggcattcaa gaggctcttt aagagagtta cgggttttaa actattaagc
      361 cttctccaat tgcaagaggg cttcaatctc tgctagggtg ctagcttgcg aaatggctcc
      421 acggagtttg gcagcgccag atgttccacg gagatagtga ggagcgaggc cgcggaattc
      481 acgaactgcg acgttttctc ctttgaggtt aatcaatcgt ttcaagtgtt cgtaggcgat
      541 cttcatcttg tcttcaaatg tcaaatcagg taggatttct cctgtttcaa agtaatggtt
      601 gatttggttg aagaggtaag gatttcccat ggcagctcgg ccaatcatga ctgcgtcagc
      661 accaacttct tcgatgcgtt gcttggcttc ttggacagta cggatatcac cgttggcgat
      721 gaatggaatc ttggttagag cttgggcaac cttgtaaagg gtctcaaggt ccgcgtggcc
      781 agtatacatt tgttcacggg tacggccatg catggcgagg gcagaaacac ctgcagcctc
      841 agcagcgagg gcattttcta ctgcaagaga tgggtccgcc cagccggtac gcattttgac
      901 agtaagtggg atatcaagga cagactggac cttgttgatg atagagtaga tcttgtcagg
      961 atccttgagc cacatagcac cagcttcgtt cttcacgatt ttgttgacag ggcagcccat
     1021 gttgatatcg acgatatcgg tcttggtgtt ttcttggatg aattctgctg cgcgtgctag
     1081 gctgtcttca tcgctaccaa aaagttggat agagacaggg ttttcgccct catcgatatg
     1141 aagcatgtgc agggtttttt cgttgttgta ttggattccc ttgtcagaga ccatttccat
     1201 tacaacgagt ccagctccga gctcttttgc tatggtacga aaggctgagt tggtcacgcc
     1261 agccataggc gctaaaacgg tacgattggg aatctcaata ttgccaatca taaaaggtgt
     1321 attaagattt gtcacgaatg agttcctcca ggtccttttc atcaaagttg taagtagttt
     1381 ggcagaattg acaagtgatt tctgcaccgt ggtcttcctc tttcatttcc tgtaagtctg
     1441 agcttggaag gctggcaaga gcgttcataa agcgttcatg gctacagtca cattggaaac
     1501 ggatttcttc ttcagaaaga cgcttgtagg cttcgtcccc gtagatagcc ttgaggaggg
     1561 cttcgatatg gtcgtcgctt tcgagaagag tagagatagc tggcatttct tggatgcgtt
     1621 tttcaaagcg agcaatctct tctttcttgg ctcctggcaa gacttgaact aggaaaccac
     1681 ctgcaacctt gaccttgtct tcctcgtcca aaaggacatt gaggccgacc gctgaaggcg
     1741 tttgttggct ttcagtaagg taaaaggcaa ggtcttcacc gatttctcca gagatgaggg
     1801 gagttataga gttgtaagga tttccagtac cgtagtctgt gataacgagg aattgaccat
     1861 ttccaacaaa aggtccgact aggacttcac cagtcgcagt ctttttgatg tcaacaccag
     1921 gattttgaac atagcctttg acgttcccct tggtatcagc gacggtgata atagcaccta
     1981 gagagctaga tcccaacacc ttaactgtaa gtttggtatt tcctttttca ttggctgcga
     2041 gaatctggct ggcgataaga gttcgaccaa gcgctacagt tgagctagct tgggtttgat
     2101 gtttttcttg agcagtgcgg acggtttcag tgctatcaag gacaaaagca cgaaaggctc
     2161 cgctttctga tatagtttta ataattttat ccatagctac tattttagca taaaaatgcc
     2221 caaaggggga gccgtgtgtt tactgatttt caggataatg gaccaggaaa tcagcatgaa
     2281 aataaaaaga gaaacagatt attttagcat ttgtaagatt tatgctatgc ttaaggtaga
     2341 aaatgaaagg gataacaaat gtatttagga gatttgatgg agaaagccga gtgtggtcaa
     2401 ttttcaatcc tttcctttct attacaagag tctcagacga ccgtcaaggc tgtaatggaa
     2461 gaaacaggat tttcaaaagc aaccctaacc aaatatgtca ccctgctcaa tgacaaggct
     2521 ttggatagtg gcttagaact gactattcac tcagaagatg aaaatctgcg tctgtctatc
     2581 ggtgcagcta ccaaggggag agatattcgg agcttgtttt tggagagtgc tgttaaatac
     2641 cagattttgg tttatcttct ctaccaccaa cagtttttag cccatcagct ggctcaagaa
     2701 ttagtgatta gcgaggctac gcttggtcgt cacttggctg gtttaaatca gattttgtca
     2761 gaatttgatt tatccatcca aaatggacgt tggcgaggtc cagagcatca gattcgctat
     2821 ttctatttct gtcttttccg aaaggtctgg tcgagtcagg aatgggaagg tcacatgcag
     2881 aaaccagaga gaaaacagga gattgccaat ttagaggaaa tctgcggtgc aagtttgtct
     2941 gcggggcaga aattggactt ggttctctgg gctcacatca gtcaacaacg tcttcgggtc
     3001 aatgcttgtc agtttcaagt tatagaagag aaaatgcgag ggtattttga caatatcttc
     3061 tatcttcgtt tgctgagaaa ggttccgtcc ttttttgctg ggcaacatat tccactagga
     3121 gttgaggatg gtgagatgat gatattcttc tcttttctcc tatctcatcg cattcttcct
     3181 cttcatacta tggagtatat tcttggtttt ggagggcagt tggcagattt actgacgcaa
     3241 ttgattcaag aaatgaagaa ggaggaacta ttgggggatt atacagagga ccatgtcacc
     3301 tatgaactca gtcagctttg tgctcaagtc tatctctata agggctatat tttacaggat
     3361 cgctacaagt accagttaga gaatcgtcat ccatatttac tgatggaaca tgattttaaa
     3421 gagacagcag aggagatttt tcatgctcta cctgcttttc aacaggggac agatttagat
     3481 aagaagattc tctgggaatg gctccagtta atcgaatata tggctgaaaa cggtggccag
     3541 catatgcgga ttggtctgga tttgacatct ggttttcttg tcttttcaag gatggcagcc
     3601 attttgaaac ggtatttgga atacaatcgt tttattacca ttgaagctta tgaccctagt
     3661 cggcattatg atttgctggt taccaataac cctattcata agaaggaaca gacaccagtc
     3721 tattatttaa aaaatgactt ggatatggaa gatttggcag ggattcgtca gttattattc
     3781 acttaaaagg cttggttaat ccaggtcttt tttgtgaaat tcacacaatc tcctcacatt
     3841 tttttaaaaa ttaaaaaaag ttgataaaca agaaagcgct ttattttgta tactagtaag
     3901 tgtaaagagg aaacacctca agatctttat caggaggaca gtacatgtca caagaaaaat
     3961 acatcatggc cattgaccag ggaactacaa gttctcgtgc catcattttc aacaaaaaag
     4021 gggaaaaggt tagctcgagt caaaaagagt ttacccagat tttccctcaa gcaggttggg
     4081 ttgagcacaa tgccaatgaa atttggaact ctgttcagtc agttattgcg ggtgctttca
     4141 tcgaaagtgg tgtcaagcca aatcaaatcg aggcaatcgg gattaccaac caacgtgaaa
     4201 caacggttgt ctgggataag aaaacaggac ttcctatcta caatgctatc gtttggcagt
     4261 cacgccagac agcacctttg gctgagcaac taaaaagcca aggttatgtg gaaaaattcc
     4321 atgaaaagac tggtttgatt attgatgctt acttctctgc taccaaggtt cgttggattt
     4381 tggatcatgt agaaggtgct caagagcgag cagaaaaagg ggaattgctc tttggtacta
     4441 tcgatacttg gttggtttgg aaattgactg acggtgcggc tcacgtgact gactactcaa
     4501 atgcagctcg taccatgctt tataacatta aagaactcaa atgggatgat gagattttgg
     4561 aaatccttaa cattccgaag gctatacttc cagaagttcg ttctaactcc gaaatctacg
     4621 gcaagacagc tccattccat ttctacggtg gagaggtgcc aatctcaggt atggctgggg
     4681 accaacaagc agccctcttt ggacagttgg cttttgagcc aggtatggtt aagaatactt
     4741 atggaacagg ctctttcatc atcatgaata ctggggaaga gatgcagttg tctgaaaaca
     4801 acctcttgac aaccattggt tacggaatca acggtaaggt ttattatgcc ttggaaggtt
     4861 ctatcttcat cgcaggaagt gctattcagt ggcttcgtga cggtcttcgc atggttgaaa
     4921 attcaccaga atctgaaaaa tacgctcgtg attctcacaa caacgatgaa gtttatgtcg
     4981 ttccagcctt tacaggtcta ggcgctccat actggaacca aaatgctcgt ggttccgtct
     5041 ttggtttgac tcgtggaaca agcaaagaag actttatcaa ggcgactttg caatctattg
     5101 cttatcaagt gcgtgacatc atcgacacca tgcaaatgga tactcagacc gccattcaag
     5161 tactgaaggt ggatggtggt gcagccatga acaacttcct catgcagttc caggcggata
     5221 ttttaggcat tgacattgca cgtgctaaaa acttggaaac aacagctcta ggagcggcct
     5281 tcctagcagg tttgtcagta gggtactgga aagacttgga cgagttgaaa ctcttgaacg
     5341 agacaggaga actctttgag ccatctatga acgaatctcg caaggaacaa ctctacaagg
     5401 gctggaagaa ggctgtgaaa gcaactcaag tctttgcgga aatcgatgac taatactcaa
     5461 tgaaaatcaa agagcaaact aggaagctag ccgcaagctg tacttgagta cggtaaggcg
     5521 acgctgacgt ggtttgaaga gattttcgaa gagtataata ctggcagaat aaagcgattt
     5581 atttagaaag tgtgtaaata tggaattttc aaagaaaaca cgtgaattgt caattaaaaa
     5641 aatgcaggaa cgcaccctgg acctcttgat tatcggtgga ggaatcacag gagctggtgt
     5701 agccttgcag gcggcagcta gcggtcttga gactggtttg attgaaatgc aagactttgc
     5761 agaaggaaca tctagtcgtt caacaaaatt ggttcacgga ggtcttcgct acctcaaaca
     5821 attcgacgta gaggtggtct cagatacggt ttctgaacgt gcagtggttc aacaaatcgc
     5881 tccacacatt ccaaaaccag atccaatgct cttaccagtt tacgatgaag atggagcaac
     5941 ctttagcctc ttccgtctta aagtagccat ggacttgtac gaccttttag caggtgtgag
     6001 caacacacca actgcgaaca aggttttgag caaggatcaa gtcttggaac gccagccaaa
     6061 cttgaagaag gaaggcttgg taggaggtgg agtgtatctt gacttccgta acaacgatgc
     6121 gcgtctcgtg attgaaaaca tcaaacgtgc caaccaagac ggtgccctca ttgccaacca
     6181 cgtgaaggca gaaggcttcc tctttgacga aagtggcaag attacaggtg ttgtagctcg
     6241 tgatctcttg acagaccaag tatttgaaat caaggcccgt ctggttatta atacaacagg
     6301 tccttggagt gataaagtac gtaatttgtc taataaggga acgcaattct cacaaatgcg
     6361 cccaactaag ggagttcact tggtagtgga ttcaagcaaa atcaaggttt cacagccagt
     6421 ttactttgac acaggtttgg gtgacggtcg tatggtcttt gttctcccac gtgaaaacaa
     6481 gacttacttt ggtacaactg atacagacta cacaggtgat ttggagcatc caaaagtaac
     6541 tcaagaagat gtagattatc tacttggcat tgtcaacaac cgctttccag aatccaacat
     6601 caccattgat gatatcgaaa gcagctgggc aggtcttcgt ccattgattg cagggaacag
     6661 tgcctctgac tataatggtg gaaataacgg taccatcagt gatgaaagct ttgacaactt
     6721 gattgcgact gttgaatctt atctctccaa agaaaaaaca cgtgaagatg ttgagtctgc
     6781 tgtcagcaag cttgaaagta gcacatctga gaaatatttg gatccatctg cagtttctcg
     6841 tgggtctagc ttggaccgtg atgacaatgg tctcttgact cttgctggtg gtaaaatcac
     6901 agactaccgt aagatggctg aaggagctat ggagcgcgtg gttgacatcc tcaaagcaga
     6961 atttgaccgt agctttaaat tgatcaattc taaaacttac cctgtttcag gtggagaatt
     7021 gaacccagca aatgtggatt cagaaatcga agcctttgcg caacttggag tttcacgtgg
     7081 tttggatagc aaggaagctc attacctagc aaatctttac ggttcaaatg caccgaaggt
     7141 ctttgcactt gctcacagct tggaacaagc gccaggtctt agtttggcag acaccttgtc
     7201 ccttcactat gcaatgcgca atgagttgac tcttagccca gttgacttcc ttcttcgtcg
     7261 taccaatcac atgctcttta tgcgtgatag cttggatagt atcgttgagc cagttttgga
     7321 tgaaatggga cgattctatg actggacaga agaagaaaaa gcaacttacc gtgctgatgt
     7381 cgaagcagct ctcgctaaca acgatttagc agaattaaaa aattaagaaa aaataaaaga
     7441 ggtggagggc agcattcctt gtcgcccgtc ccttcttttt aatggagaca gaaagatgat
     7501 gaatgaatta tttggagaat ttctagggac tttaattctg attcttctag gaaatggtgt
     7561 tgttgcaggt gtggttcttc ctaaaaccaa gagcaatagc tcaggttgga ttgtgattac
     7621 tatgggttgg gggattgcag ttgcggttgc agtctttgta tctggcaagc tcagtccagc
     7681 tcatttaaac ccagctgtga ccatcggtgt ggccttaaaa ggtggtttgc cttgggcttc
     7741 cgttttgcct tatatcttag cccagttcgc aggggccatg ctgggtcaga ttttggtttg
     7801 gttgcaattc aaacctcact atgaggcaga agaaaatgca ggcaatatcc tggcaacctt
     7861 cagtactgga ccagccatca aggatactgt atcaaacttg attagcgaaa tccttggaac
     7921 ctttgttttg gtgttgacaa tctttgcttt gggtctttac gattttcagg caggtatcgg
     7981 aacctttgca gtgggaactt tgattgtcgg tatcggtcta tcactaggtg ggacaacagg
     8041 ttatgccttg aacccagctc gtgaccttgg acctcgtatc atgcacagca tcttgccaat
     8101 tccaaacaag ggagacggag actggtctta cgcttggatt cctgttgtag gccctgttat
     8161 cggagcagcc ttggcagtgc ttgtattctc acttttctag tttatactct tcgaaaatca
     8221 aattcaaacc acgtcagcgt cgccttaccg tactcaagta cagcttgcgg ctagcttcct
     8281 agtttgctct ttgattttca ttgagtatta gaaaacaatt atgttgatag agcttgggca
     8341 agagcccaat ttcagcaaaa aatgaagtaa atcttctcat aataaaacgc atcatatcaa
     8401 gcacgaaaat tccacgaggt caactacagt cagaaagctg aacaacaagc caaaacgccc
     8461 aaaaaaggcg gcaaaaagca agcacctgca agcaacgtgc cgaaatggtc aaatcctgat
     8521 tatgtcaacg aattagaccc aaaaatcgtt gatatgctag tagaatttca caagtcacaa
     8581 ggcactttgg aaactcccga ggcgcaagca gaaatcgccc aaaaacgtga agaaatcgag
     8641 caaaggagag ctgagcttga ggataaaaaa caagagcttt tgaaccgctt gaacaaatag
     8701 agtttcgcaa gtattatgct tacaaattac ttgagcaatt aactaaaata taaaccctgc
     8761 ctttatatct aggcagggtt tatattttag aaattcacgt aggttgttac ggtttttaca
     8821 tacccagtat agtttgagtt tctatagtat tcagtgataa acttccattt tctttgagca
     8881 acatggatat aagtacttgt tatgtagtat ggatatgggc tttgtgaatc caagtaagac
     8941 tgataagctt gtataccaaa atatgctcca ccaattattg caccccatgg accccccaat
     9001 aaagcaccta tcctaccaat catataactg attccagcac cagtcatgaa gttagcgaat
     9061 gtgttagctt gtttattccc atgtattgtg ttgacgtaat ttcaaacatt aggatcgtat
     9121 gatctaaaag atatatttag gtcgatttca ttcttttgat aagccatata aaatgcccca
     9181 ttgatataga cgccgtcagc acgtcgttca atagtgtcta cacttccatc tggattgaca
     9241 acctcaagaa cttcatcgct taaaatattt acttgcgtat ctccgaaccg cactgatgag
     9301 ccattctcaa actgagcctc accagataca actttagagt ttgccgataa gctatcatca
     9361 gcaaaaacaa caagcgacgg ggaaatgcta gacatacaga aaacagacat aactagcaaa
     9421 cacatgcatt taaacatctt agacataacg gaaactcttt tgtatttttg atttttttca
     9481 acttttatta tacaataaaa ccaaataaaa agaaagcggt aacaatatgc ttaatgcgaa
     9541 aattttttat atatttttat gtttgatcgt tatcgaaact acaggcttgt tgttgttgaa
     9601 aagaggtctc gaaatgggtt atttagacac agaagctatt atcctcgcag ttttttcatt
     9661 tgctttttac aacctatgtt cattcgcttg ggtctgctct acaataaaaa acaataaaaa
     9721 ataaatagac gtattttcaa aaaaaaaaaa aaatgcatat ttatcttagc aaaatgacga
     9781 tttaaatcgt cgtttttttg tagtacgacg ggcatgtcgt atatctgagg tgtaagtcct
     9841 cggtgggcac ctgctaccgg tgaacccaat agcgattccc aagcctgact atcgtgaggt
     9901 agcagggaga ggaagggata gcgaaatcgt ggctctacga acaggaacgt gatagtaagg
     9961 cgtatatagc ggataaggag gcttcaaact ctaaagtcca aaaaggtagt cgtaacctat
    10021 atgtgtaaat cacgagagta attgaattcg gactaaggtt tgtgtgaaaa agataaatct
    10081 ttctagagtc taaagactct gcgtcagatt tcctattttc actgtaacct tttaacgtcc
    10141 tcatatcttg tataaacgag gaaagatgta cgacttatcc cgtgaggttt catgagcgct
    10201 gaaagcgtag taacaacgaa tcatgagaag tcagccgagc ccatagtagt gaggaaactt
    10261 ctgtagtgga agtggagcga cggggtgaat actcaaacag tctggggaga gactgtttga
    10321 ggtctgtcgc tagaaagaga aaacgacaga tcgaagtaat cctacttcac ttgtgtctgt
    10381 aaaatgagtg gtctgataga actggacttt gacacgtaat gactagatga aggttcacca
    10441 atataagatg tccctcaggc accaaaacaa gaaaggaata ggcacatgtc aaaactgcta
    10501 gataagatat tatcacgcga aaatatgctg gaagcctaca atcaagtaaa atccaataaa
    10561 ggctcagctg ggattgatgg aatgactatc gaagagatgg ataattatct cagacaaaac
    10621 tggcgcttga ctaaggaact gataaaacag agaaaatata agcctcaacc agttcttaaa
    10681 gttgagatac ctaaaccaga cggaggcatc cgtcaactag gaattccaac agttatggat
    10741 agaatgattc aacaggccat tgtccaagtc atgagcccca tttgtgaacc ccatttctca
    10801 gatacgagtt atggtttcag accaaatagg tcatgtgaaa aagccatcat gaagctctta
    10861 gaatacttaa atgacggcta tgagtggata gtggatatag acctagagaa atttttcgat
    10921 acagttcctc aagatagatt gatgtcctta gtacataaca ttatcgaaga cggagatacg
    10981 gaatccttga ttcgtaagta tcttcattca ggtgttatca ttaatggtca acgttataaa
    11041 acactagttg gtacaccaca gggaggaaat ttatctcctc tcttatccaa tatcatgctt
    11101 aatgaattgg acaaggaatt agaaaagagg ggacttcgat ttgtgcgcta cgcagatgat
    11161 tgtgtgatta cggtcggaag cgaggcagcc tctaagcgtg tgatgtattc agtcagtcgt
    11221 tttattgaga aacggctagg tttgaaagta aacatgacca agactaagat taccagacca
    11281 agagagttga aatatctagg ttttgggttc tggaaatcat cagatggttg gaaaagccgt
    11341 ccacatcaag atagtgttcg gagatttaag tttaaattga agaaactaac acagaggaaa
    11401 tggagtatag acctaacaag acgtattgag caactgaatt tgtc
//
LOCUS       DAVBNZ010000062        11410 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000062 DAVBNZ010000000
VERSION     DAVBNZ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11410
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.062"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ860_001800"
     CDS             complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ860_001800"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET3120188.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEITYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2224..3483)
                     /locus_tag="VQ860_001801"
     CDS             complement(2224..3483)
                     /locus_tag="VQ860_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3120189.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3485..4186)
                     /locus_tag="VQ860_001802"
     CDS             complement(3485..4186)
                     /locus_tag="VQ860_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3120190.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4170..5369)
                     /locus_tag="VQ860_001803"
     CDS             complement(4170..5369)
                     /locus_tag="VQ860_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET3120191.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5634..6980
                     /gene="gor"
                     /locus_tag="VQ860_001804"
     CDS             5634..6980
                     /gene="gor"
                     /locus_tag="VQ860_001804"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET3120192.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDSSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFTSMYSACTCNRQETRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMRATKADFDATVAIHPTSSEEFVTMR"
     gene            7176..7712
                     /locus_tag="VQ860_001805"
     CDS             7176..7712
                     /locus_tag="VQ860_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET3120193.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7763..7849
                     /locus_tag="VQ860_001806"
                     /pseudo
     CDS             7763..7849
                     /locus_tag="VQ860_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7918..8133)
                     /locus_tag="VQ860_001807"
     CDS             complement(7918..8133)
                     /locus_tag="VQ860_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET3120194.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8231..8551
                     /locus_tag="VQ860_001808"
     CDS             8231..8551
                     /locus_tag="VQ860_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120195.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8582..8920)
                     /locus_tag="VQ860_001809"
     CDS             complement(8582..8920)
                     /locus_tag="VQ860_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120196.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ860_001810"
     CDS             complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ860_001810"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET3120197.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQVYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ860_001811"
     CDS             complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ860_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET3120198.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10190..10978)
                     /locus_tag="VQ860_001812"
     CDS             complement(10190..10978)
                     /locus_tag="VQ860_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3120199.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(11082..11325)
                     /locus_tag="VQ860_001813"
                     /pseudo
     CDS             complement(11082..11325)
                     /locus_tag="VQ860_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
BASE COUNT         3274 a         2508 c         2077 g         3551 t
ORIGIN      
        1 cagtgctttg atcaacccgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
       61 aaataaaaaa acagaactag tctgaactag tcctgtctac ttttacccaa tcacacttcc
      121 atttggtaca gctggatcaa ctgtgagaag ggttaatttg ccatcatgtt cagctgatag
      181 aatcataccc tggctgacat attttttcat cattttacgt ggtttgaggt tagcaacgat
      241 ttgaactttc ttgccgacca attcttgttc atttggatag tattttgcaa ttcctgaaag
      301 aatctgacga tcttctccat caccagcatc caagcggaat tgaagcaact tatctgaacc
      361 ttctacttta gacacttctt tgacttctgc gacacggatt tcaaccttgt caaagtcttc
      421 aaacttgatt tcatccttgt ttagtttgag ctcaacttcg tccggattcc attctttttc
      481 gactgctggt ttattgcctt ccatttgttc cttgatatag gtgatttctt cttccatatt
      541 tagacgtgga aagataggtg ttcctttggc aactacagtc acatctgctg ggaagtcagc
      601 caaactcaag ttttcaagac tagaaacttc ttccaaacca agttgagtca aaactgcacg
      661 actagtttcc atcataaatg gttcaatcaa gtgagcaact acacgaatgc tggctgccaa
      721 gtggctcatg acacttgcca attggtcacg aagagcttca tccttggcca agacccatgg
      781 tgcggtctca tcgatgtatt tattggtacg agagatcaga gtccagactg cttcaagcgc
      841 acgtggatag tcaactgctt ccatgtgtgt atggaagtct gcgattgatt gttctgcaac
      901 ctcagcaaga acatgatcaa attcagtcac accttctaca taggcaggga tttgtccatc
      961 aaagtactta ttaatcatgg aaaccgtacg gttaaggagg ttcccaaggt cattagccaa
     1021 ttcatagttg atacggccga catagtcttc aggagtaaag gttccgtctg aaccaactgg
     1081 aaggttacgc atgaggtagt aacgaagtgg atctagtcca taacgctcta ccaacatttc
     1141 agggtaaacg acattccctt ttgacttaga catttttccg tctttcatga caaaccaacc
     1201 atgggcaatc aaacgatcag gtaatttaac atccaacatc ataagaagga ttggccagta
     1261 gatagagtgg aagcgaagga tatcttttcc taccatatgg aagactgttc cattccagaa
     1321 cttgtcaaag ttaccatgtt cgtcttgagc gtagccaaga gctgtcgcat agttaagaag
     1381 ggcatcaatc caaacgtaga caacgtgttt tggatttgat gggacaggca ctccccatgt
     1441 aaaggttgta cgagataccg ccaaatcttc caaacctggc tcgatgaagt tgcgtagcat
     1501 ttcattaagg cgaccatctg gcgtgataaa ttcaggatga gctttgaaaa attcgaccaa
     1561 acggtcttgg tatttgctaa ggcgaagaaa gtatgattct tcagaaaccc attcaacctc
     1621 atggcctgat ggagcaatac caccagtcac atttccagct tcatcacgga aaacttctgc
     1681 cagctggctt tctgtaaaga attcttcgtc tgatactgaa taccaaccag agtattcacc
     1741 caagtagata tcatcttgag caagtaagcg ttcaaagact tgtgcgacaa ctttttcatg
     1801 gtagtcatca gttgtacgga taaatttatc gtatgagata tctagtaatt gccagagttc
     1861 tttaactcca accgccattc catcaacata ggcttgaggt gtaataccag cttcttccgc
     1921 tttctgctgg attttctgac catgttcatc aagacctgtc agataaaata catcgtagcc
     1981 catcaggcgt ttgtaacgtg ctaggacatc acatgcgata gttgtgtagg cagaaccgat
     2041 atgaagtttc ccagatggat agtaaatcgg cgttgtaata taaaaatttt tttcagacat
     2101 aatttttcct ttccaggcaa atgaaacctg tttttctaac acttcattat atcacatttt
     2161 taatgaattt cgatagggaa atccatacaa aaacaagata gacgagtgtc catcttgttg
     2221 atctcattca taacgaaggg cttcaattgg atcaagtttc gatgccttgt tggctggcaa
     2281 gactccaaaa atcataccaa cactagccga aactgcaaga ctaaataggg caactgggat
     2341 tgatactcca acttctatac cttctattaa accttgcagt aacaaacctg ctaaggcagt
     2401 taaaccactt gcaattgtca agccaattaa gccacctaac aaggtcaaaa tcatggattc
     2461 aatcaaaaac tgaattaaaa tattggcacg tgttgcgccc aaagccttac gaagaccaat
     2521 ctcacgagtg cgctctgtca ccgaaaccag catgatgttc atgacaccag ttcctccaac
     2581 aaagagagaa atccctgcga tggaactaat aatcgtcgtc ataaaactaa acgattgttg
     2641 aatttctgca aatacaacgg actcatctgc cacctggtat tctccctgtt gtaagcctgc
     2701 aagctctgtc atttttcgtg ccagttctgg acccagagtt ggggttaaac tggtatcatt
     2761 cactcgaaag acaatactag ctatttcatc tatattaaaa ttcgcagcaa gggagatatt
     2821 ggtagtaata ggcaagccac caaacccata tatttttgac cttttagcct ccggactagt
     2881 ataaacccca atgacccggt aactaaatcc attgacttct acaaccttgt taatagcctc
     2941 ttgaggagat tcaaataaac taatggacaa ttcctcatct agcaaaataa cacttgcaaa
     3001 ctctttgaaa tcttgctctc tcagactacg acctgcaata atttcattct taacagcgtc
     3061 catgtaagtt ctgtttccac ctgtcaaatt agcattctca acctttttat cttgataggt
     3121 caagatggca ttcgttgaat tggttacata gtaactatcc actcccttca gtttagctgc
     3181 ctcttgaacc caggattctt gcggttttgg cggttcaaca ggaacttcct cttcctttcc
     3241 agaaaccgta aaagctgatt gtttctgagt aaaagaccca tctttacttt ttttaggaga
     3301 gaaaaagacg ctaatatttt tctgagattt agtcatatct ttattgactt gacgagatag
     3361 ggaatcaccc aaagccataa tcacaacaac tgatgaaaca ccgataataa tcccaatcat
     3421 agtaagcaaa gaacgcatct tgtgagccat gatagatgaa aaggcaaatt tcagattctg
     3481 catcttagtt ttcctccttt cctaactgag cactgtcaga cgaaatgacc ccatcccgaa
     3541 tgacaatctg acgtttggca taggcagcaa tctcaggctc atgcgttacc atgataatgg
     3601 tttttccttc tttattcaaa tcaaccaata attgcataat ttggttacct gttttggtat
     3661 ccaaggctcc tgtcggttca tccgctagga taatagaagg attgtttacc aaggcacgcg
     3721 caatggctac acgttgcttt tgaccaccag ataattctga aggtaaatgg tgactacgtt
     3781 ctgtcaattc aaccttgtct aaatattcct cagccaactt gcgacgtttt gaagacgaaa
     3841 ctcctgcgta aatcaagggc aattctacat tttgcagagc attgagcttc gatagaagaa
     3901 agaactgctg aaagacaaaa ccgatttgtt ggttacgaac cttagctagt tgtttttcac
     3961 caagcccagc cacttcttga ccttcaagat aatattctcc actggttggt gtatccaaca
     4021 tgccaatcgt attcatcaga gtggacttac cagaaccaga tggccccatg atggctacaa
     4081 attcaccctc attcacttct agattgatat ttttgagaac ctgcagttct tggtcaccat
     4141 tacggtagct tctgaagata ttttttagac taattagttg cttcatcagc cttcacctct
     4201 tttccttctt ccaaggaaga tgttggatta ctgatgacct tagcaccatt tgtcaaacca
     4261 gaagtgattt cttgattttc tgcgtcagca tttcccaatg aaacctcaac ttttttagcc
     4321 ttttgttgtt catccacaat ccagacataa tttttactat catccattac tagactgcta
     4381 acaggaacaa gaatagcctt agttttgctt ttaacctcaa tgttgacaga aaaaccttgt
     4441 ttcaaatcac caacctcgcc tgtcacatca atagtataag ggtatttaga acctgtatta
     4501 ttcccggctg ctggactagc tgcttcacca ttgtttttag gatagtcaga aatatagctt
     4561 aatttcccag tccatttttt atcaggatac actttagaag taaagcttac ttcttgacct
     4621 acagaaaggt tggctagatt gtactcagac aattctccct tgacttgtaa attttcattg
     4681 ctgacaatat gaaccataac ttgactcgcc cctgttggag atttagaaac attgctattg
     4741 acttcgacta cagttccctc tagggtactg agaacagttg ttgcatccaa ttgactttga
     4801 gccttgctta attgcgctgc agcatctgca cgcgcatcac gggcatcacc caattgagca
     4861 tcaatagaag caacagaatt tccagccact ggagttgggc tttgcaccgt tgcatcttct
     4921 cctcctactg gcgctggtaa ctgtggagcc tgagctgaag cggcttcatt tcgtgcttga
     4981 ttgagttcat tgatatgacg atctgcctta gctactgctc gactagctga atcataggcc
     5041 gcctgcgctt ctgaactact gtacttgact aaagcctgcc cttcgctgac cttatcgccc
     5101 acagaaacaa ggatttcatc taaatcaccc ttactagcat caaaataaac atattgttca
     5161 ttttttgctg ttactgtccc tgacaataaa acagaggatg ccacgcttcc ttccttggca
     5221 acaacaagat gagtaggctc atcttttaca gcagtctgag aaggttgtct aaaaagtaaa
     5281 atccccccgg cacccaatac aactacactc gcagcaccga ttgctgcata cagttgccac
     5341 tttttagctt taccattctt tttcttcata atgaaactcc ttttcttttt tacaatactt
     5401 tgctattata ccaaatttcc ctccagcaaa caatacagtt caggattaag caatcgttcg
     5461 gaatttttct tttctattgt actagatata taatacacta tcttgactta tttggcaagc
     5521 ttttttgcaa ttttttgtgc gtagcagatt tttgcaatca aatcaaaaaa agaataaaat
     5581 ataactatca aaaaagacgc tctactattt aaaagattac aaaggagttt tcaatgagag
     5641 aatatgatat cattgctatc ggtggaggta gcggaggaat cgctaccatg aaccgtgctg
     5701 gtgaacatgg agccaaagca gccgttattg aggaaaagaa attaggtgga acctgtgtca
     5761 acgtcggttg tgttcctaaa aaaatcatgt ggtacggggc gcaaatcgct gagactttcc
     5821 atcaatttgg agaagactac ggctttaaga ctactgatct taactttgac tttgcaaccc
     5881 tacgtcgcaa tcgtgaagcc tacattgatc gcgctcgttc ttcttatgat agtagtttta
     5941 aacgcaacgg tgtagacttg attgaaggtc atgctgaatt tgtagattct catactgtaa
     6001 gcgtaaatgg tgaactgatt cgtgctaaac atatcgtgat tgctacaggt gcccatccaa
     6061 gtattcctaa tattcctggt gctgagctag gtggctcttc tgatgatgta tttgcctggg
     6121 aagaacttcc agagtcagtt gccattctag gcgctggtta tatcgccgtt gaattagctg
     6181 gcgtactcca cacttttggt gtcaagacag atctctttgt tcgccgcgat cgtcctttac
     6241 gtggttttga ttcctacatc gttgaaggtt tggtcaagga aatggaaaga ataaacttgc
     6301 cacttcatac tcacaaagtc cctgccaagt tagaaaaaac tgctaaaggc attaccattc
     6361 atttcgagga tggtaccagt cacacagcta gccaagttat ctgggctaca ggtcgccgtc
     6421 caaacgttaa gagcttgcaa cttgaaaaag ctggagtgac tctgaatgaa cgtggcttta
     6481 tccaagtaga tgaataccaa aatactgttg ttgagggaat ctatgctcta ggtgatgtaa
     6541 caggtgaaaa agaactgact ccagttgcaa tcaaggctgg gcgtacccta tcagaacgtc
     6601 tctttaacgg aaaaacaact gcaaaaatgg attactcaac tattccaact gttgtctttt
     6661 cacaccctgc tatcggaact gttggtttga cagaagaaca agctattaaa gaatacggtc
     6721 aagaccaaat caaggtttac aaatcaagct ttacttctat gtactctgct tgcacttgca
     6781 accgtcaaga aactcgtttc aaattgatca cagctggttc agaagaaaaa gttgtcggac
     6841 ttcacggaat tggctacggc gttgatgaaa tgattcaagg atttgctgtt gctatcaaaa
     6901 tgagagcaac caaggctgac tttgacgcaa ctgtagcgat tcacccaact tcatctgaag
     6961 aatttgtaac catgcgttaa tcgaaacaaa agaagctgat ataaatatgt ctgcttcttt
     7021 tttaatgatt ttcgaatcaa caaaaaatta tccaacttga ctagtcacga aaatcggctg
     7081 ttacagtttt tgttaccttg tttttaaaaa atggttgaca tcgactccta tatgagtata
     7141 atagttacta tacattagaa aagaggttaa ctattttgaa aaaagctcac gtttatgcta
     7201 tccctgctat tggggctgct ctcattgctg ttttggcaca aatcagtctt ccaattggac
     7261 ctgttccctt cactctgcaa aactttgcaa tcggcttgat tgctactgtc tttagaccga
     7321 gagaggctgt actttctgct ggactctatc ttcttctagg tgctatcggt cttcctgtct
     7381 ttgcaggagg tggagctggt tttcaggctt tagttggccc tactgcaggc tatctttggt
     7441 tttatctcgt ttactctgga cttacttcct ctctaaccaa cagcaagagt ggtgttgtta
     7501 agatttttct tgcaaacctc ttgggtgatg cccttgtctt tgtcggcggg attctcagct
     7561 tgcatttcct agctggaatg gcatttgaaa aagctcttgc tgtgggggtt cttcccttta
     7621 tcattccaga ccttggcaaa cttctggcta ttagttttat tagccgtccc ctacttcaac
     7681 gccttaaaaa tcaggcttac tttactaact aaaaaaggat atcgagttat catgactcaa
     7741 tatccttttc ttttattttg aaaacttata ctcaatgaaa atcaaagagc aaactagaaa
     7801 gctagccgca ggctgctcaa aacactgttt tgaggttgtg gatgaaactg acgaagtcag
     7861 taaccataca tacggcaagg caaagctgac gcggtttgaa gagattttcg aagagtatta
     7921 gttgccttta aaggcatcca ccatcgtttg aaattcttca tttgagagag taatcccttt
     7981 gcccatttta gtatggtctg gactccaagc acgaatatca aactttgcag gggcaccatt
     8041 aaagctcaca cggttaattt ccttggtcca acctttttcg ttttcagaaa gagtcaacaa
     8101 gtgctcttcg atttcaaatg taaattctgc cattttcttc tcctttttta gtttcattag
     8161 tttattcgta aaatcttgta gattttagga aaattttata taatattgat ataaaagaag
     8221 ggaggccaat atgagacata aattccagca agttctaaat aaaatacatg attttttaaa
     8281 tggatatgac caacctgacc agactgaaac caactccctt acagccacta ttgaagaggc
     8341 tatccagaaa caaaccgctg ttcaccttat cttgtctgag acaagtttta caggtgatat
     8401 catcaaatat gatcagcaag gccagcaaat tatcgtgaaa aattttgcca aaaatgtgag
     8461 ccggattatc cgtataagcg atattcaacg cctgcgattt gtcccctcaa ctgtccaaac
     8521 agcccaaaaa aatagattta agaaagagtg agatgtagtt gcttcatccc actctttttt
     8581 cttagcgaat ttgttcaaaa tgtaaatgaa ctgcaatatg atctccataa ccacttcttt
     8641 ccaagtcacg ttgtaaacga taggaaatgt agtgttctgc aatggtaatg taacctgcgc
     8701 ccaataaacg atgttcaacc atagattgaa tcatactgat agtcgcacgt tccaccttgg
     8761 cttcttgtaa atccaaaact accttcttag tgacttgagc aagattttga cgcaaatcat
     8821 ctgtcaaaac ataaacagtt tgggctgcct tcaagatggc ttggtaaatc ttatctggat
     8881 taaattcagc aatttcgcca ttacgtttga ttacttgcat aggtttctcc tttattcttt
     8941 gttttctttg atttctgcca gcattttttc ttcttctact gtcagttgat aatgttcaag
     9001 taaatccggt ctgcgctcgt aggttttctt taaactctcg tacaatcgcc actgacgaat
     9061 cttttcatgg tggccactca tcaatacatc tggcacgacc atgcctcgat aatcataggg
     9121 acgtgtgtac tgaggatatt ctaaaagacc tgaagaaaaa ctatcatctt ggtggctaga
     9181 ctccttgcca atcacttctg gaatcaggcg aactgtagca tcaatcatgg tcatagctgc
     9241 caattctcca ccagtgagga catagtcgcc tagggaaatc tcatctgtta ccaaggtctt
     9301 aatgcgctca tcataaccct catagtgccc acagataaag attagctctt cctcttgagc
     9361 caaatcttca gcataaacct gatcaaactg ctttccagca ggatcgagga gaataacgcg
     9421 cggatttttc ttttcaatag catcaaagga atcgaaaata ggttgtgctc tgagcaacat
     9481 gccctgaccg cctccgtagg gctcatcatc tacatgacgg gccttttcag cattttctcg
     9541 aaaattatga tactggatat ccaagagccc tttttctcga gcctttccaa cgattgagtg
     9601 ctccagtgga gaaaacatct ctggaaagag ggttaaaata tcaatcttca tcgtctaacc
     9661 cttctaagat ttccacatcg acccgtttat ttggaatatc aacattgaga accactggtg
     9721 ggatataagg taaaagcaaa tcacgtttgc cttttcgttt gaccacccag acatcattag
     9781 cacctggttg caggatttcc ttgatggttc caaccaagct atcaccctca tagacttcca
     9841 aaccgataat ctcgtgatag taaaattcac catcgtctag gtcattcaaa tcttcctcag
     9901 cgaccttgag actgtatccc ttgtactttt cgatagtatt gatatggtac atatctttga
     9961 atttaataat gtcaaagttc ttctgtttac ggtggctagc gatggtcact gtttggacaa
    10021 actgatcttt ttcatcaaac aaagccagct cagctccttt tttaaaccgt tcttctgcaa
    10081 aatccgtcac agacaagact cgcatctcac cctgtaatcc ctgcgtatta acgattttcc
    10141 caacattaaa gtagttcatc ttgtctcctg taatctcctt ttttccatct tattctgaca
    10201 attctcgaat aatagccgca attttttccg attctgacca ttgtaaataa tggtgattcc
    10261 ttcctaaaat gagtttagta ttggaagtcc aatattctga ttctctgtac tctttttctc
    10321 tataagtctg acaaaaaata aatacaggga catgagattc tatcgacaaa ttctcaaaat
    10381 cttcctcagt aatctctcca gatatctgaa attctggatc ttgattttcc aactctaagc
    10441 ctttttcttg cattaattcc cagatttttt tattcgtttc aggactaaat gttgcttgag
    10501 ttaagttctt aaaataaagt tcaggaccac actcgtcaat cagcctcatc tgctcttcca
    10561 tttctggata aggattttct gaaaaatcag caaacatgac ttttttagtt gtcggttcaa
    10621 ttgctactaa agtctgacgc ttaattggtt tctcgagtaa tttgcaagct aaaattccac
    10681 tccaactatg tgcacaaagt atatattcag aaattcctaa ttcttcaagt acttcataaa
    10741 ccgcatctgc aagattatct agattttttc cagcttggtc atgaatcgga ctcctacctg
    10801 tgttcggaaa atcaattgtc aaataaccaa ttgtaggagg aggtttttca agtataagtg
    10861 aaaaattttc ataacttggt agcaaacctg ctccgtttag acaaactagc actttctttt
    10921 gcttttgata agtaacagag aggctaccaa tttctgtaga tacttcaaac ctcttcataa
    10981 agaaatccac tcattctata taatgaatta ttaaaaatcc ttatccttta ttttatcacg
    11041 ttccaaagat tttctcaagt tggaggaagg ggacaacatc tctactttcc cttcaagaat
    11101 ccttccaaat catgtttatg ttggtaatta acggctgcgg ttttgtcttt ctcaaagatg
    11161 gttctagtta ggtcaatatg cttgatagca gcaatagcga cggtgtagtg aatgatatca
    11221 gccagttcta tggcaggttc ctcgttcgaa tcctatccct tcttttcgac cagagcgcct
    11281 attcaaaacc tcggctactt ctccgacttc ctccactaac ttcataaaga gaccttcatc
    11341 agtccgagac tgctgttaat gttcgagtaa gtagtcttgg aattgcctaa acgttcaatc
    11401 ttttatagta
//
LOCUS       DAVBNZ010000063        11266 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000063 DAVBNZ010000000
VERSION     DAVBNZ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11266
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.063"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(392..1528)
                     /gene="dnaJ"
                     /locus_tag="VQ860_001814"
     CDS             complement(392..1528)
                     /gene="dnaJ"
                     /locus_tag="VQ860_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET3120200.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1733..2086)
                     /locus_tag="VQ860_001815"
     CDS             complement(1733..2086)
                     /locus_tag="VQ860_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120201.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(2099..3922)
                     /gene="dnaK"
                     /locus_tag="VQ860_001816"
     CDS             complement(2099..3922)
                     /gene="dnaK"
                     /locus_tag="VQ860_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET3120202.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4402..4926)
                     /gene="grpE"
                     /locus_tag="VQ860_001817"
     CDS             complement(4402..4926)
                     /gene="grpE"
                     /locus_tag="VQ860_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET3120203.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4953..5987)
                     /gene="hrcA"
                     /locus_tag="VQ860_001818"
     CDS             complement(4953..5987)
                     /gene="hrcA"
                     /locus_tag="VQ860_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET3120204.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(6151..6660)
                     /locus_tag="VQ860_001819"
     CDS             complement(6151..6660)
                     /locus_tag="VQ860_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET3120205.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            7268..7568
                     /locus_tag="VQ860_001820"
                     /pseudo
     CDS             7268..7568
                     /locus_tag="VQ860_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818342.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
     gene            7763..9601
                     /locus_tag="VQ860_001821"
     CDS             7763..9601
                     /locus_tag="VQ860_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3120206.1"
                     /translation="MKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQII
                     HRLRKAGLAKRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYL
                     GLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGM
                     TATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKV
                     DTNGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHA
                     ERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTT
                     GVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDF
                     DGEPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLIT
                     ESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQE
                     IDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGEL
                     ESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9614..11077
                     /locus_tag="VQ860_001822"
     CDS             9614..11077
                     /locus_tag="VQ860_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3120207.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            11077..>11266
                     /locus_tag="VQ860_001823"
     CDS             11077..>11266
                     /locus_tag="VQ860_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HET3120208.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         3435 a         2207 c         2212 g         3412 t
ORIGIN      
        1 ccatggcaag ccgacgctga cgtggtttga agaaattttt gaagagtatc attcaccatt
       61 tcacaactaa atcgaagact ttctgccgta atgaaaacac ctgaaacagc ttggtttcag
      121 ctgtccggaa actttaagac ttaggttcaa agtttaggta tggaacttcg aaggaggtcg
      181 ctaccgtccg tcattactta ggaaagtctt aaaaaatcta taaagtaaaa agagcccgac
      241 agctcttttt gtttatactc aatgaaaatc aaaaagcaaa ctaggaaact agccacgggc
      301 tgctcaaaac actgttttga ggttgtagat acgactcaca tatatacggc aaggcaacgc
      361 tgacgtggtt tgaagagatt ttcgaagagt attattctcc atcaaaggca tcttttatat
      421 ggtcaaagaa gccttttttc tttggattta ctttcaagtc accagcagtc gcgaattctt
      481 tcaaggctac tttttggcgg tcgttcaagc ctgtcggtgt tacgacatta acagtaacgt
      541 attggtcacc aactgcaccg ccacgaaggc tcggtgcccc cttactacgt aggcggaatt
      601 tcttaccagt ctgagttccc tctggaataa ccaattcaac atcaccgtga acagttggaa
      661 tatctactgt atcaccaaga gccgcttgga caaagttgag gttgagattg tagaagatag
      721 tcgttccttc acgttcaaac ttgtcgctag cttctacaga aactactaca tacaagtcac
      781 cataaggtcc accgttaaag cctgcttcac cttgaccagc gaggcgaatt tgttgacctg
      841 tttccacacc agcagggatt ttcacatgta cgctatgagc ttgtttctca tgacctgttc
      901 catgacaggt tgtacatgga tatttgattt cttttcctcg accgtgacag acatcacagg
      961 ttacttggcg acgcatcata ccaagaggag tctgcgtatc gacgttaatg acaccagcgc
     1021 catgacagcg tccacaagtg actggacttg tccctggctt agcaccagag ccattacatg
     1081 tacgacagcc agcttcacga tgatacttaa cttccttctc agttccgaag atagcttctt
     1141 caaatgtcaa attgacacga tactggagat catctccttg gcgaggagcg tttggattgc
     1201 gcgaagaacc gcctccgccg aagaaacttg agaaaatatc ctcaaaacca ccgaagccac
     1261 ctgccccatt gaaaccaccg aaaccaccag ctccaccaaa accaccattg gcgcctgcag
     1321 caccatactg gtcataggca gcacgttttt ggtcgtcact caaagtctca taggcttctt
     1381 gaacttcctt gtacttgtcc tcagcaccag gctccttgtt gatatctggg tgatattttt
     1441 tggaaagctt acgataagcc tttttgatct cgtctgccga agcgtttttt gacaccccca
     1501 gacgatcata aaattcagta ttgttcatac aagataccaa gaccgtaaaa ttcgactgaa
     1561 aaataggaaa tctgacgctg gagcgacgct cctagacaga tttctctttt ttccgagaat
     1621 ttaggtcggg ttcaattcct ttcttttata ttgatgagat aatactccag ccactcggcc
     1681 ctatcccttt ttaccgaaaa acagaggctg ggttgcaacc tctgtggtta gattattcat
     1741 ttgaaataaa aatggttgta ttatctctag tagtaatctt caaagacctt ttagctaaat
     1801 caaactcaaa tttattatag tgtgggtctt gtgttttata taggtgtaac tcctgacata
     1861 tatgatccga aaagtaaatc ataacatctt taaacacaga agtgtagtca tatttactct
     1921 taccaacagc tacttctgta aattctttat aaatgacatt tccatttctt tccacagtca
     1981 ccagcatttc tgttggatta taatccaaat taaataattc ttcaaaaaac tttatctttt
     2041 catgataatc tgcaatgtca gaaagattat ttttattaac actcataaca ctagcccctt
     2101 atttttccgt aaactctccg tctacgacgt catcgcctgc gtttcctgtt gcttgtgcgc
     2161 cttctgctcc ttcttgagct tgttgcgctg ctgcggcttg ttcgtagagt ttaacagcaa
     2221 gtccttgagc tttttcgttc aatgcttcaa gtttcgcttt catgtcgtcc aagttgttgt
     2281 cttcttgagc tttcttaagg tcatcaaggg cagcttgggc agcgtcacgt tctgcgtcga
     2341 agcctttacc ttcagtttcc ttgattgtct tttcagtcgc aaagattgct tggtctactt
     2401 cattacgaag gtctacttct tctttacgtt tcttatcggc ttcagcgttt gcttctgcat
     2461 ctttcatcat gcggtcgatt tcttcgtcag tcaaacctga gttcgattgg atgacaatag
     2521 tttgttcttt ttgagttcca aggtctttgg ccttaacaga cacgataccg ttcttgtcga
     2581 tgtcaaatgt tacttcgatt tgaggaattc cacgaggtgc agctgggata tcagtcaatt
     2641 ggaagcgtcc aagagtcttg ttatctgctg ccattgggcg ttcaccttga agaacgtgga
     2701 tatcaacggc tggttggttg tctgctgctg ttgagaagac ttgtgattta gatgttggga
     2761 ttgtagtgtt gcgatcgata agttttgtaa atactccacc cattgtttcg ataccaagtg
     2821 acaatggcgt tacatcaaga aggacaacgt ccttgacatc accagtaatc acaccacctt
     2881 ggatagccgc acccatagca actacttcat cagggtttac tgatttgttt ggttctttac
     2941 cagtttcagc tttaacagct tcaacaacgg cagggatacg agttgaacca ccaacaagga
     3001 taacttcgtc gatttctgac aagctcaaac ctgcatctga aagggcttga cgaactggaa
     3061 cttttgtacg ttcaacaagg tcacgagtca aatcatcaaa tttcgcacga gtcaaagtca
     3121 tttccaagtg aagaggtcca gcctcacctg cagtgataaa tggcaagctg atttgtgttg
     3181 aagttacacc agaaaggtct ttcttcgctt tttcagccgc atctttcaaa cgttgcattg
     3241 ccatcttgtc agtagacaag tcgataccgt tttctttctt gaattctgct accaagtggt
     3301 caatgatttt ttggtcaaag tcgtcaccac caagtttgtt gtcccctgca gttgacaata
     3361 cgtcgaagac accgtcaccc aattcaagga tagagacgtc gaatgtacca ccaccaaggt
     3421 caaataccaa gattttttct tctttatcag tcttgtccaa accataagca agagctgctg
     3481 cagttggttc gttaacaata cgttctactt caagaccagc aattttacca gcgtcttttg
     3541 ttgcttgacg ttgagcgtcg ttgaagtaag ccggaactgt gataacagct ttggttactt
     3601 tctcaccaag gtagtcttca gcgtagcctt tcaagtattg aaggatcata gctgagattt
     3661 cttgtggagt gtattctttt ccatttgcag aaactttttc agaagttccc atcttagatt
     3721 tgatagagat aactgtatct gggtttgtga ctgcttgacg ttttgcagca tcaccaacga
     3781 tgatttctcc gtttttgaat gagactacag atggagttgt gcggtttcct tctgggtttg
     3841 cgatgatttt gctttcagtt ccttcaagaa ctgcaactgc tgagtttgtt gtacctaagt
     3901 caataccgat aattttagac atgtgttttt ctccttgtta gttaattttc tatttttctt
     3961 tttgatactc ttcttaagtg gcgacgccgt cagagcttga cttcgtcaat ctctttgact
     4021 aaactttgag cctaaggtct caaaatttgc gcaaatagcg ccacggcgaa gagtatcgtg
     4081 tttggttcgc ttcgctcact attacaaagc caaacatatt ttatctttct tcatagttta
     4141 ttgtcgtttc ggacaagttt tctattatgt aaattgcgac acgaagagtc gaaatcgatt
     4201 ttatttcgac gacgagttag taaggaagct aggcaaacgc catagcgatt gccgttttct
     4261 gacgagttgc tttagctacc gtcagaattg ccgaatcgaa cacgccctaa gctctgagta
     4321 aaaaagatag attttcttgt gttcatcgaa cacttcgtta atctcctatt tttactgcga
     4381 gctttttacg ggctttgtat cttagttata caccactacc attgctgggc gtaggatgcg
     4441 gtcatggagt ttgtagcctt tttgaaagac ttgagcgatg gtatctactg ggtgttcatc
     4501 gtctgctggg agagtttgga tggccatatg gtagttatgg tcaaattcgc catctgctgc
     4561 gatttcttca attccttctt ctttcaaagc gtgaatcaag ctttcttgca ccatccccaa
     4621 gcccttcttc acatcatctg tcaaaccttc aactgcaagt gcacgctcaa ggttgtcaag
     4681 agatggtaag attgcttttg ccaagtcctg gctacgataa cgttgcaagt tttgacgttc
     4741 ttcattggca cggcgttgga tattttgcat ttctgcatga gcgcgaagat atttgttttc
     4801 gaactcatct gcacgttcat ttgccaagtc caactcagac ttttcaggag ttgtttcttc
     4861 agctgtttcc acaacttcct cttcttgaac ttcttctact tcttcatttt ttatatcttg
     4921 ggccatgttc gcctccttta atgatttcaa tcttaatgta cttcgtaatg attactgctg
     4981 aggtagcggt aaaaatctgt caacttcatg gtcaaaacac ggttgaccac attgatttga
     5041 ttgattagct gttggtaatc cagattaact ggaccgataa tggctagaat tccaactccc
     5101 cgataaggaa tgaggaactt actactaatc accgctaggt cagctaaaca ggactcttga
     5161 ccgtctgcaa tacgaacatt ttgcatctga tcctcacgca acccctcacg aatctccaag
     5221 gccacctttt gcggttggtc aaagaactga taggctgcta gattggcaaa attcaagaga
     5281 ttgaccttgc ccgccatcac aatgttttcg ttgaacattt ccttaaagat gtgttcaaag
     5341 agatcgatga cattatccgt tgttgtaaag taacgctgga taatctgcgg aatctccgtc
     5401 cgaatcttgt agtgaatatc taaaacggtg tgaccgagga aacgttcctg aatgatgctc
     5461 ttcagtttca gcaaatcctc ctgcaagaag ttccttggaa tcagaaactg actagtaacc
     5521 gttcgcgact cgtctagggt aaataccgcc aaggctgtat gttgccccaa aacaacgata
     5581 tcaaaggctg tcaaacgttg cctgctcggc tcaacatcca gtgccactac cgtacagcca
     5641 ctcaggtctg ttagcaagtt agcagcctct tgcagaatat cctccaattt gaagaattcc
     5701 tgatcaaagg ctttgacaat ctcatatacc tcattttcag ccagccggtg aaaatccagt
     5761 gagtgtttca catagtactg aaaaccagca acacttggca tccgaccgct tgaagtatga
     5821 gccttctcaa gcaacccttg tttttctagt tccgccatgt cattacgaat ggttgcactg
     5881 ctagagttaa tagactcttg caaggctttt gatccgacag gttcgtgcgt tttggtaaag
     5941 atgtcaataa tcagatttaa aatatcctgc tgacgctctg taaccatctc atcactcctc
     6001 tctgtctgat caattagcac tcaatgcatc caagtgctaa cttatgattc tattatacac
     6061 ccttagaaga gaatgtcaag acaaaaactc aaaaaattag cactctttta tcaagagtgc
     6121 taaaaatcaa tctgaagacc tagaaccttg ctattcatct actcggtatt tcctttttag
     6181 tctgaaataa ccatgaatta gataagaaat cagaaaagca tataaaacaa aaataagaaa
     6241 gaaagacata gaaagatcct ctctaaacaa actcgtacaa acaacaagac cacctaagaa
     6301 agtagctgta caggaacgaa gtctagatcg cataacttcc catttgagcc ccttactcat
     6361 atagacttga tcctctggaa gtaaatcaga agacgattta cgaagaatcg aacaagaacc
     6421 tgctcctatc aattcccaac ctctatctct aaaatcttgc agttcatgct tatatttttt
     6481 aagaaatcta gaatcataga tacggtagat gacatcgtct ggttgacatt ggtcaaaata
     6541 gaacaaacca aaacgactcg ttctatacct ccaacctttc aaatgcatct catgtaaata
     6601 ttcttctttc ttgtccaaat caacaatggt gaaaatccga aattctactc tgctattcat
     6661 tgtcttaccc caaaattaga aaacatgcct agcgttattt attagataat tctttccact
     6721 tttgactcaa tctccaaaaa atataagaaa tctgaatcgc aaaaactatc aataaaaccc
     6781 aatctattat gaaaatcaaa aacacttccc aactgaaaga actacctcca gtgacaaact
     6841 ttgagaaaaa cggtagtaga gctaaaaaga gaagcaaaat aggaagcatc cgcattgtta
     6901 aaatccgttt ggcataaaaa aatctttatt taaacgaaaa tattatggca aaatttacgc
     6961 cagtttttga acggctgatg tagatatttt atactttcaa aatgtttaaa tgtgattatt
     7021 tatttttgaa aaatagctca ccagcccgac tgaaagtgct tatagaatga taataagtcg
     7081 cctgccgaaa acagcggaaa atagcggtgt tatgcggaga taatctgacg cgatgcgaaa
     7141 gtatattgca tacttatttt caacaattta gcagagtatt tttataagtg tgatataata
     7201 gaagtataat ttgttctgat agtttatttt atggagaagt agatttttag aatgcggagg
     7261 gttcaatatg gttgagttta taaagtctaa gaaagaaatg agtgaggagg atattaaagc
     7321 aaatttcatc actcctgcta ttgtatccaa aggatggaaa aatggtgagc atatcgctta
     7381 cgaagaatac ttcactgatg gtcgaattga ggttagagga gataaggctc gtcgtaaaga
     7441 aggaaaaaaa tcagactatt cactgtatta ccaatttgga actcgaattg caattgttga
     7501 ggcaaaggat aataaacaca gcgttcgagc aggattacaa caagctattg aatatggaga
     7561 gattttagat gttccatttg tttattcttc aaatggtgat ggctttattg aacacgaccg
     7621 tatcacgaga gaagaacgtg agctggagtt agacgaattc cctactcgtg aagaattatt
     7681 ttctcgtatg acgaaggaaa aaggattgac gtacgaaatt acagaagcta tctaaactcc
     7741 atactataca gacgccttct caatgaaaac gccacgctat tatcagcaaa tagctatcaa
     7801 ccgtactatt gaaacagttg ccagaggaca aaaacgagta atgtttgtga tggcaacagg
     7861 aacggggaaa acgttcatgg cttttcaaat tattcatcgc cttcgaaaag ctggtttggc
     7921 taaacgagtt ttattcttag cggatagaaa catcttagta gaccaaacga tggctgaaga
     7981 ctttaagcca ttcgaaaagg taatgacgaa aattacacca aaacttttga ctgctcctga
     8041 aaaattaaat tcttttgaaa tttatctagg gctttatcag caactaactg gtgaagatgg
     8101 aactgaaaca cattatcaaa aatttgacaa agacttcttt gatttaatcg taattgatga
     8161 agcgcaccgt ggttcagcta aggaaaacag taactggcgt aagataattg attatttcag
     8221 ttctgcgaca cagattggga tgaccgctac tcctaaagaa accaagaatg cttccaatac
     8281 ggaatacttt ggtgagccaa tctatactta tagtttaaaa cagggaatcg aggatggttt
     8341 tttggctcca tatcgtgtta tgagggttaa tttagatgtg gatgtggatg gttatcgtcc
     8401 agaaactgga aaagttgata ctaacggaca attaatagaa gataggtact acggcaggaa
     8461 agattttgat aaaaccattg tcattgatga tagaacgcaa agagttgcca agtttgtttc
     8521 tgattatatg aagcaaagca atgcacgatt tgataaaaca attgtttttt gtgttgatat
     8581 tgaccatgcc gagcgaatgc gtgctgcact tgtaaaagag aatctagact tagtccaaga
     8641 agactatcgt tatgtcatgc aagtaactgg tgacaacgct gaaggaaaag ctcaactgga
     8701 taactttatg gatgtcaatt ctaattttcc cgctattgta acaacgtcta aattattaac
     8761 gacaggagtt aatgctaaaa catgtcgttt gattgtttta gactctaata tccaatccat
     8821 gactgaattt aaacaaatta ttggtcgtgg cacacgtctt tatcctcaaa aggggaaaga
     8881 attttttacg attattgatt ttcgaaatgt taccaatttg tttgctgacc ctgattttga
     8941 tggtgagcca gtgaaggtgc tggaaacagg tgcgaaaaca gtcagtggtt ccacgcccgg
     9001 tttcgtagat gaggaaggtg acccagtaga aaaatatatc gttacagaca agcaggttac
     9061 cattcttaat tctactgttc aagtattgga tgaaaacggg aaactgatta ccgaaagcct
     9121 gaccgactac actcggaaga atatcttagg tagctacgcc actttgaacg attttatcac
     9181 agtttggcat acggcggata aaaagaagct tatcttagac gaactttata aaaaaggagt
     9241 ttatctagat gctattcgag agtcggaggg aatatcagaa caagaaatcg atgattttga
     9301 tttactccta aaacttgcct atggtcaaaa agaattaacc aaaacggaac gtatcaataa
     9361 actcaaacaa agcggatatt tatataaata tagtgaggaa gcgcgtgctg ttttggaaat
     9421 tttactgaac aaatacatgg ataaaggtat tggagaactc gaaagcattg aaacattaaa
     9481 acttccagaa tttcagatat atggtggaac cttcaaaatc atcaatactt attttggaga
     9541 taaaaaacga tatttacaag caattaaaga attggagcaa gagctattta cagtagctta
     9601 atgaaaggaa agtatgtcaa ttacatcatt tgtaaaaaga attcaagata tcactcgaaa
     9661 cgatgctggt gttaatggtg atgctcaacg tattgagcaa atgtcttggt tattattctt
     9721 aaaaatttat gatagccgtg aaatggtttg ggaattagaa gaagacgagt atgagtcaat
     9781 tatcccagag gaattaaaat ggcgaaattg ggctcatgct caaaatgggg aacgggtatt
     9841 gacaggcgat gaattacttg attttgtcaa taacaagtta ttcaaagagt tgaaagagct
     9901 tgaaataact tcaaatatgc ctattcgaaa aacgattgtt aaatcagctt ttgaagatgc
     9961 gaacaactat atgaaaaatg gcgtcttgtt acgccaagtc atcaatgtta ttgatgaagt
    10021 tgatttcaat agccctgaag atcgtcattc gtttaatgat atttacgaaa aaattcttaa
    10081 agatattcaa aatgctggga actcaggaga attttatacg ccacgtgcag cgactgattt
    10141 tattgccgaa gttcttgacc caaaacttgg agaatcaatg gcagaccttg cttgcggaac
    10201 aggaggcttc ttgacttcga ctctgaaccg tttaagtagt caacgtaaaa ctagtgaaga
    10261 taccaaaaaa tataatacag ctgtttttgg tattgaaaag aaagcatttc ctcatctttt
    10321 agcagttaca aatctgtttc ttcacgaaat tgatgaccct aaaattgttc atggaaatac
    10381 tttggagaaa aatgttcgtg aatatacgga tgatgaaaaa tttgacatta ttatgatgaa
    10441 tccacctttt ggagggtcag aattagaaac aataaaaaat aactttccag cagaattacg
    10501 gagttctgaa acagctgatt tatttatggc tgtcattatg tatcgtttga aagaaaatgg
    10561 tcgtgttgga gttattttac ctgatggttt tctatttggt gaaggtgtaa aaactcgctt
    10621 gaaacaaaaa ctggtagatg agttcaactt gcatacgatt attaggttgc ctcatagtgt
    10681 ctttgcaccg tatacaggaa tccatacgaa cattcttttc tttgataaaa caaagaaaac
    10741 agaagaaact tggttttatc gtttagatat gccagatggt tataaaaatt tctcgaaaac
    10801 taagccgatg aagtcagaac acttcaatcc tgttcgtgac tggtgggaaa atcgtgaaga
    10861 gattctggaa ggtaagttct acaaatctaa atcatttaca cctagtgaat tggctgagtt
    10921 gaattataat ttagaccagt gtggttttcc aaaagaggaa gaggaaatct taaatccctt
    10981 tgagttgatt cagaattatc aagcggaaag agcaacttta aatcataaga ttgataatgt
    11041 attagctgat attttgcagt tgttggagga caaataatga caccagaaca acttaaagca
    11101 agtattctcc aaagagcgat ggaagggaaa ttagtgccgc aaaatcccaa tgacgaacct
    11161 gcaagtgaat tattaaagag aattaaagct gaaaaagaaa aacttatcag tgaaggaaaa
    11221 atcaaacgag ataaaaagga aactgagata tttcgtggtg atgatg
//
LOCUS       DAVBNZ010000064        11085 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000064 DAVBNZ010000000
VERSION     DAVBNZ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.064"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ860_001824"
     CDS             <1..116
                     /locus_tag="VQ860_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3120209.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK"
     gene            140..1063
                     /locus_tag="VQ860_001825"
     CDS             140..1063
                     /locus_tag="VQ860_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HET3120210.1"
                     /translation="MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSK
                     VQSNKIRVYDGKFNLLFEQDGQISPDKGITIEVENEIYYILGSSIYRITIDESVEEIC
                     IGDFDFQLESGYGCYYNGHLFFGFQESYLFNIETKELFKKSDFPVSGRGQGLSVKYQN
                     ELYYLGGANNEAYLDGYKYIFEKDKWEKLEFELPSSVLGASSIQINESDLLILGGFNE
                     IAYNKAVIDLATPGYREEYFSKGRDFFNWNRSLRILDLETGKVDIIANDERFALCGAG
                     FLKTDNGYYVVSGECSPGRRTSDILLLEEEM"
     gene            1145..2773
                     /locus_tag="VQ860_001826"
     CDS             1145..2773
                     /locus_tag="VQ860_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3120211.1"
                     /translation="MKKIVKLALTAAAVLIAVVGLVACSSGSKKSDSSESGKEKVFYL
                     SGLLQGTGDRIPYVWQNGDGLVPYLLYRTLLMADSKYEKSTPDLAKDWKKSDDEKTYE
                     FTLKDGLKWSDGEALTASDVEFSVKLALKASVINGIFPSTFTKIEGAKDFKDDKADKI
                     SGLTVDGNKVTFKLTAPVGNFEQMMTQFFILPKHKLESENPLELNNSSFWTAPVTSGM
                     YKVKEISAGNFLEYDKNENYENEKPKFDKVVFNYISDPVLALQDGKSYFYSTNKPQEI
                     SQLDAVSTLTKKPIDILFYRYFIANLAGVEGNGDSLIANPKVREAILYAINRDELAKS
                     VFSGIADVNNTGVPSSLEAHLKSANKFEYNPEKAKQLLKEAKYDNSRNLILAYYYKDQ
                     ASQDFMQAVSYQLNEVGIKNEVVQITSDATTGLFKTRKYDLAYKGLSSFGYETWYGEY
                     SSTNTNFKNITNGETSFDELSKKLSETSDVKERNKILASLQKLEQEKLLKLNLFTFKN
                     FLYLNTEKVLIPDDVQFGNPFYKFDYKFEKWDAK"
     gene            2882..3832
                     /locus_tag="VQ860_001827"
     CDS             2882..3832
                     /locus_tag="VQ860_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3120212.1"
                     /translation="MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMA
                     SSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFE
                     LAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
                     LRILPIGGRFTSGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKT
                     ARAKGVPEWKVYFKHIFRNAMRPILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSS
                     VTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY"
     gene            3849..4700
                     /locus_tag="VQ860_001828"
     CDS             3849..4700
                     /locus_tag="VQ860_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3120213.1"
                     /translation="MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYS
                     PDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLG
                     GIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
                     MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAG
                     LSFLGVGVPSDIPTWGNIINAAKTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRD
                     IMDPKQQ"
     gene            4713..6695
                     /locus_tag="VQ860_001829"
     CDS             4713..6695
                     /locus_tag="VQ860_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3120214.1"
                     /translation="MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGES
                     GCGKSVTVNTVLNLLPKNGRIAEGEITYFDEDKPIELQKLKQYGKEFRKLRGENISMI
                     FQDPMSALNPVYTIGNQITEVLHEHYDISKEEANKRAIKMLEKLGIHNAAERMNDYPH
                     QFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTSIILI
                     THDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMDKKLH
                     VIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHFFFED
                     KEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTTIGIV
                     GESGSGKSTIAKSLMKLHEITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDP
                     YASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKESLKMVNVPVEYLERYPHEFSGGQ
                     RQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGV
                     VKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKE
                     NEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            6705..8114
                     /locus_tag="VQ860_001830"
     CDS             6705..8114
                     /locus_tag="VQ860_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120215.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDIKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            8119..8607
                     /locus_tag="VQ860_001831"
     CDS             8119..8607
                     /locus_tag="VQ860_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HET3120216.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
     gene            8895..9302
                     /locus_tag="VQ860_001832"
     CDS             8895..9302
                     /locus_tag="VQ860_001832"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3120217.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYFPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGTSQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLNGKGNILELRLEELVPYSFSSLEM"
     gene            9334..10251
                     /locus_tag="VQ860_001833"
     CDS             9334..10251
                     /locus_tag="VQ860_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3120218.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKDVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEDLNIGSVR
                     SPLTPVTEEDRPVVEEAAALIRETKERFL"
     gene            10278..10472
                     /locus_tag="VQ860_001834"
                     /pseudo
     CDS             10278..10472
                     /locus_tag="VQ860_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(10622..>11085)
                     /locus_tag="VQ860_001835"
     CDS             complement(10622..>11085)
                     /locus_tag="VQ860_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3120219.1"
                     /translation="YAMFDKEQKRGYKQSARNLANWHYNDKEDSYTHPDGWYYRFHHT
                     KYQKTQTDFQQKIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQR
                     KIDVEPVFGQIKACLGYKRCNLRGKRQVRIDMRLVLMANNLLKYNKRTTQN"
BASE COUNT         3694 a         1665 c         2114 g         3612 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggaatc gttgttggtg
       61 gcgctattac tagaccaaaa gagattacag aacgttttgt agcgggatta aaatagcatg
      121 ccagagtaag aggtgtaata tgaaaattga tgttataaat catttagact caccaggatt
      181 agctgggatg atttgtagac ggattaataa tagaatttta gtttatggag gtagttattt
      241 cccaaataac gatcctttaa aaagttcaaa agttcaatca aataaaatta gagtttatga
      301 cgggaaattt aatcttctat ttgaacaaga tggacagatt tctccagata aaggaataac
      361 gattgaagtt gaaaatgaaa tctattacat tctaggctcg agcatttatc gtattacgat
      421 tgatgaaagt gtagaagaaa tctgtatcgg ggattttgat ttccaactag agagtggtta
      481 tggttgttat tataatggcc acttattctt tggatttcag gaaagttatc tgttcaatat
      541 tgagactaaa gaacttttta aaaaatctga cttcccagtt tctggtagag gacaaggttt
      601 atcagtcaaa tatcaaaatg aattgtatta tttaggtgga gcgaacaatg aagcttattt
      661 agatggatac aaatatattt ttgaaaaaga taagtgggaa aaacttgagt ttgaattacc
      721 aagttcagtt ttaggagcgt caagtataca aataaatgaa agtgatttat taatccttgg
      781 tggctttaat gaaattgctt ataataaagc agttattgat ttagcaaccc ctggctatag
      841 ggaagaatac ttttctaagg gaagagattt ctttaattgg aatcgtagct tgcgaatact
      901 agatttagag acaggtaagg tcgatattat tgcaaacgat gagcgttttg ctctttgtgg
      961 ggcaggattt ttaaaaactg ataatggata ttacgttgtt agtggggaat gtagcccagg
     1021 aagacgtact tctgacatac ttttgttaga ggaggaaatg taacgaagag tttaaatttt
     1081 taattactgc aatacttact taatcacata aataattact taatacaaat aaaggagtat
     1141 taaaatgaaa aaaattgtta aattagcttt aacagctgca gcagttttaa tagctgtagt
     1201 aggattggtt gcttgtagtt cgggaagcaa aaaatctgat tcttcagagt ctggaaaaga
     1261 aaaagtattc tatttatcag gtttgcttca aggaactgga gatcgtatcc cttacgtttg
     1321 gcaaaatggt gatggtttag ttccatattt gttataccgt acactgttaa tggcagattc
     1381 aaaatatgaa aaatcaactc cagatttagc taaagattgg aaaaaatctg atgatgaaaa
     1441 aacttatgaa tttacactta aagatgggtt gaaatggtct gatggagaag ctttgacagc
     1501 ttccgatgtg gaattcagtg ttaaattagc attgaaagct tcagtaatta atggaatttt
     1561 cccttcaaca ttcacaaaaa ttgaaggagc taaagatttc aaagacgata aagcagataa
     1621 aatttctggt cttacagttg atggaaataa agtaacattt aaacttactg ctccagttgg
     1681 taactttgag caaatgatga ctcaattctt tattcttcca aaacataaat tagagtctga
     1741 aaatcctctt gaattaaata atagctcatt ttggacagct cctgttacaa gcggtatgta
     1801 caaagtaaaa gaaattagtg caggtaattt cttagagtat gacaaaaatg aaaactatga
     1861 aaatgaaaaa ccaaaatttg ataaagtagt attcaactat atttcagatc cagttttagc
     1921 attgcaagat ggtaaatcat acttctattc aacaaacaaa cctcaagaaa ttagtcagtt
     1981 ggatgctgta tctactttaa ctaaaaaacc aattgatata ctattctatc gctactttat
     2041 cgctaactta gcaggtgttg aaggtaatgg agattccttg attgctaatc ctaaagttag
     2101 agaagctatt ctatatgcaa ttaatcgtga tgaattagct aaatctgtat ttagtggaat
     2161 tgcagatgtt aataatactg gtgttccttc aagcttagaa gctcatctga aatcagcaaa
     2221 taaatttgaa tataatccag aaaaagcaaa acaacttctt aaagaagcta aatacgataa
     2281 tagcagaaat ctaattttag cttattacta taaagatcaa gcctctcaag atttcatgca
     2341 agcagtaagt tatcaattga atgaggttgg aatcaagaac gaagttgtcc aaattacttc
     2401 tgatgcaaca acaggattgt tcaaaacacg taaatatgac ctagcttata aaggattatc
     2461 atcatttggt tatgaaactt ggtatggtga atatagttca acaaatacta actttaaaaa
     2521 tattacaaat ggcgaaacaa gttttgatga gttgagcaaa aaattgtctg aaacttctga
     2581 tgtaaaagaa agaaacaaaa ttttagcaag tctacaaaaa ttagaacaag aaaaactatt
     2641 gaagttaaac ttattcacat ttaaaaactt cttgtattta aatactgaaa aagttttaat
     2701 tcctgacgat gttcaatttg gtaatccatt ctataaattt gattacaaat tcgaaaaatg
     2761 ggatgctaaa taaaatcgtt taaaattatc agtgattaag tttgataatc ttttaggagt
     2821 gtagagatgc tgtttattga atcatgtatc tctcactctt gttttttcag gagaaattaa
     2881 aatgaaaaaa tatattctaa aaaaagtatt attcatgatt cctatgttgt tgattattag
     2941 ctttttagta ttcattgcac tagatttaac accagcagat ccattgacat atatggtatc
     3001 tccagatatg gctagtagtg cagaacaaat cgaaaagcta agacagcaat taggtttaaa
     3061 tgatccagta ttagttcgct atggaagatg gctttggcaa ttactccatg gtgattttgg
     3121 atacagtatt gtaaatggta acccaatttc caaaattgta ggacaagcat tgcctgcaac
     3181 ttttgaatta gcttttgtgt cattaattat ttcaacaatt gttggtattg taattggggt
     3241 tatatcagcc gttaaacaaa atggtattat cgataatgtt gctcgttttc tagctgttat
     3301 cggaactgcg attccacaat ttttctttgg tattttaatt ttaaacttct ttgcaattca
     3361 gttaagaatt ttacctattg gtggtagatt taccagtgga gattttacat ttattaatag
     3421 agttgaacac ttaattctac cagtaatggc tatgtcaatt gcattggtag ccgctttaat
     3481 gagatacaca cgtaattcta tgttggatgt ttttaatgca gattatgtta aaacagctcg
     3541 tgcaaaaggt gttcctgaat ggaaagttta ttttaaacac atatttagaa atgctatgcg
     3601 accaatttta gtgttattga ttttccgtct accaatgtta attggtggat cagtaattat
     3661 cgagagtgtc ttttcttggc ctggaattgg ttctatcatc ctatctagtg taacagcagg
     3721 tgactatcct gtaattatga ttaccacatt aatgatttct gtcgtagtgt tatttgctag
     3781 tctacttgta gatattatgg ctgcaatatt agacccacgt attcgttatt aggaaggagg
     3841 tcaatgttat gaaacctatg cctttatgga aaagaaattt gaaaaaattc tataataaca
     3901 aattggcctt tatcggcttt atatgcttca tgctaattct attagcatgt attctagcac
     3961 ctttattgac aacctattct ccagatgttg ttgatttagg atctatgaac cgtcctcctt
     4021 cagcaaaaca cattctggga acagataaac taggtcgtga cgtatttgct cgaatcctat
     4081 atggtggtcg agtttcaatt caagtaggga tgtatggagc gatttgtgga gcggttattg
     4141 gtactgtact tggtggtatt gctggatatt ttggtgggaa aattgatgct cttctagttc
     4201 gtctagcaga attattctta acattcccga atatgattgt cattctcttg ctttcaagta
     4261 tttttggaca aggtgtattc aatcttatct tcgtattctc agtaatgggt tggatgacaa
     4321 cgttccgaat ggttcgtaat gagttcatgt ctttgaaaca agaaacatat gtggatgtat
     4381 gtagagcttt tggtttttct gacagtcgaa ttatctttaa taatatttta agaaatgcta
     4441 tctcaccagt aattgtatcg ttgtctttaa acgttgctgg tttcattctc agtgaggcag
     4501 gtcttagttt cttaggagta ggtgttcctt ctgatattcc tacttgggga aatatcataa
     4561 atgctgccaa aacagccgat gttattaaaa atagttggtg gctgtggtta gttccagggt
     4621 caatcattac tcttttcgtt ctttctatca actttattgg tgatggatta cgagatataa
     4681 tggatccgaa acaacagtag gaggttgaca aaatgaatca aacagtttta gatgtaaaaa
     4741 acttaaaaac tgaattcatc actgataaaa aagcatttcc gattattaaa gatgtaaact
     4801 tcactttgga aagagggaaa gttttaggga ttgttggtga atctggatgc ggtaagagtg
     4861 taacagtgaa tacagtgtta aacttattac ctaaaaatgg acgcattgct gaaggtgaaa
     4921 tcacatattt cgatgaagat aagccgatag agcttcaaaa attaaagcaa tatggtaaag
     4981 aatttcgaaa gttacgtggt gaaaacatat caatgatttt ccaagatcca atgtctgcat
     5041 tgaatccagt atatacaatt ggtaatcaaa ttactgaagt ccttcatgaa cattatgaca
     5101 tttctaaaga ggaggcaaat aaacgtgcta taaaaatgtt agaaaaactt ggaattcata
     5161 atgctgcaga acgcatgaat gactatccac accaatttag tggagggcag cgtcaaagaa
     5221 tagtcatagc gattgcaatg gtatgtaatc cagatattct aattgcagat gaaccaacaa
     5281 ctgcccttga tgtaacaatc caagcacaaa tacttgattt acttgatgat ttacgtaaag
     5341 agcatggaac ttctattatc ttaattactc acgatttagg cgttattgct caaattgcgg
     5401 atgaagttgc agtgatgtat gctggtgaag tcgttgaagt tggaactgta gctcagatct
     5461 ttgatcaacc taaacacccg tatactcgtt ctctattaag atctattcct aatcctgaaa
     5521 atatggataa aaagctacat gttatccagg ggagcgtacc ttcaatttct gaaatatctg
     5581 aaaaaggatg cagattcgca aatcgtattc catggttaga aaaagaacat catgaagaag
     5641 aacctcaatt gcatgattta ggtgacggac attttgtaag gtgttcttgc tataaacatt
     5701 tctttttcga agataaggaa gaagaaacat tagcggaaaa acatgtaggt aatgttgttt
     5761 tagaagtaaa aaatattaaa aagtactact atcctaagaa acaactattc aagccactag
     5821 gttctccgtt gaaagcactt gatgacgtat ctctagagtt aagaaaagga actactattg
     5881 gtatcgtagg agagtctgga agcggtaaga gtacgattgc gaaatcatta atgaaactcc
     5941 atgagattac agatggtgaa atcaatattg atttgaatgg gaaaactcaa aatatttatg
     6001 gaattaaacg taaggaagat ttggatttcc gtaagaaagt tcaaatggta ttccaagatc
     6061 cttatgcatc attgaaccca actaagaaaa tttataattc atttgatgaa ccgatgattg
     6121 tccataatat tggaaacaaa gaggaacgct ttgaacgtat gaaagaatcc ttgaagatgg
     6181 taaacgtgcc agttgagtac ttggagcgtt atcctcatga attttcaggc ggacaacgtc
     6241 aacgtttatg tattgctcgt gccctttgta tgaaaccaga aattttaatt ttagatgaac
     6301 ctgtttcagc attagatcta tctgtacaag cgcaagtttt gaattatctt gttgaaatcc
     6361 aaaataaaga agatttgact tatgtattta tttctcatga cctaggtgtt gtgaaataca
     6421 tgtgtgacta tctatatgtt attcataaag gacgtattgt agaagctggt tctcgagaag
     6481 atatctacaa taacccaatg catatttaca ctaaaaaact attagctgct attccagaag
     6541 ttgattatca cttcaaagag gcattggcaa caaaacgtaa agaaaatgaa gttgaattta
     6601 aagcacagta ccatgaattt tatgatgaag atggccgtgc ttatgatctt aagcaggttt
     6661 caccaacaca ttttgtagcg ttaaaaccag aataggtggt aaatatgaaa ttaaataaaa
     6721 aaatatattt ctttgataaa ggaattttta atccttatcg aatgagtaat gtaaaattaa
     6781 aagttaatca ggcagtaaag gataaagaaa ttttcttcac tgaggaaaaa ccatgggaaa
     6841 ttcgttttga taacagttat ccaaatgttt tctttgatga tttagcaggt gtttatcgtt
     6901 gctactattc tacatttact gatgatgagg agtctgaaaa atactcttta gaggagcgta
     6961 aggaacgtca atatctacct cgtgcgaagc gtattgtttc actttgttat gctgaaagta
     7021 aagatggtgt taactgggtg aaaccaaatc taggtattac agaatttcga ggatcaactg
     7081 aaaataatat tatcggacat tttttacatg gtacatctgt ttttctagat aaacatgacg
     7141 cagatgaaaa tcgtcgttat aaaatgttta caaagattga ttacggtaac ggtgttcatt
     7201 ttattgctgt agcattttca aaagatggtc tacactttga tgaatacatt aaagtaccaa
     7261 acttcaatcc acgtgcagac actcataacc atatcatata tgatgaagca ttaaatcgct
     7321 atgtgctaat tactcgtact tggagagatt cattgcgctt gccgtgtgta tctacgagtg
     7381 ctgatttcat taactggact ccaattcaag aaattttgaa tgtctgtgat tatgaaaatc
     7441 aaatttattc tatgcctatt tttaaacgtg gcgattatat actaggttta gcttcagttt
     7501 tccatgaagg agatcaactg aacaagaatt acgatacagt ggaccttcaa ttgacttata
     7561 gttatcgtca tgttggttgg cattatctaa acactgatac tccacttatt cctcgtggta
     7621 aaggtcaata tggtgatgga gaatttgact gtggatgtat ctattcttct gcaccagtta
     7681 ctatcggtga ccgtacttat ttctactaca tgggaggaaa tggacaacat acaaacttcc
     7741 gtgaaacaag cttgtctcgt gcttatattg agaaagatca ctttgcatat tgggatatta
     7801 aacgtccaga atatccaggt gttttgtata ccaatggatt tattttcctc aatgatcaag
     7861 tttaccttga tgcagatatt gcagctggag gctttgtaac aattgaattg ttcgagaata
     7921 atcacactcc aatggaaatt acagcttccc ttgaaaaaat agaagatggt cgctatcaag
     7981 tgttattcag cgaaccttta cctcgaactc aaactcgact gaaaattagc tttaaaaatg
     8041 ctaaaatcta cgcaatcgaa ggaaatttag atattttcag aattgaatca gacaatgctc
     8101 tattgagggg gtaagattat gaaatatgat ttatatgata attgtattga acttctaaaa
     8161 gaacgcgaag ttacaattga agatatggca gcgttagtaa tattttcaca acaaaaatat
     8221 taccctgaat taactcttga cgacgcttca tatgcaattc aacgtgtact aaaaaaacgt
     8281 gaagttcaga atgtaattat gacaggaatt gagttagata agttagctga agcacaaaaa
     8341 ctatctccag aatttcaaaa gattatggag aaagataatc cattgtatgg gattgatgaa
     8401 gtaatcgtct tatcgatatt gaatttatat ggttctattg cctttacaaa ttatggctat
     8461 ttagataaat taaaaccact gattttagaa agattgaatg agaatcacga aggtgtttgt
     8521 aatgtatttc tagatgatat tgttggtgca atagccgcag cagcatgtag taaaattgca
     8581 cacaatcatg ctagtgatga aatataacta ttgaatttag tatcgtaaat aataaagcgt
     8641 ttggtttcta gattattgtc attcaaattg gataatgata aatctagaaa ccaaatatat
     8701 tttccgcata aaatgaggga ttatatatct cactttttta caattgtata gtggattaaa
     8761 actagaatag tgcatctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat
     8821 tgatttgtac tgttcttatt tcattttact ataatttagt gtgagtaaaa tataataata
     8881 aaggagttaa aacaatgaca gtaattaata aatttgtttt aatggagcaa gcaaaaaaag
     8941 ttttaaaaaa tgcttacttt ccgtattcca aatttcctgt aggtgcagca attttattta
     9001 aagatggtaa agtaattaca ggagcaaata tagaaaatgt atcgtttggt gtaactaact
     9061 gtgcagaacg tagtgctatt ttttatggga cttctcaagg atatagaaaa ggagatattc
     9121 ttgcgattgc tgttgcaggt gaaactgaag actacttacc accatgcaac atttgtcgtc
     9181 aagttatggt agaattttgt gagcctgata ccttagtctt tctattaaat ggtaagggaa
     9241 acatacttga attgcgatta gaggaattag tcccatattc gttctcaagt ctagaaatgt
     9301 aattacgtag tatgaaataa ggagaaaaaa acaatgtcag atttgaaaaa atacgaaggt
     9361 gtcattccag ccttctacgc atgttatgat gatcaaggag aagtaagccc agaacgtacg
     9421 cgtgccttgg ttcaatactt cattgataaa gatgttcaag gtctttatgt caatggttct
     9481 tctggtgaat gtatctacca aagcgttgaa gatcgcaagt tgattttgga agaagtcatg
     9541 gcggtagcca aaggtaaatt gaccattatt gcccatgttg cttgcaataa tactaaagac
     9601 agtatggaac ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca
     9661 ccaatttatt tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct
     9721 gcagctccaa acacagacta cgttatttac aacattcctc aattggcagg ggttgctttg
     9781 actccaagcc tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt gaagaactct
     9841 tctatgccag ttcaagatat ccaaaccttt gtcagccttg gtggagaaga ccatatcgtc
     9901 tttaatggtc ctgatgagca gttcctagga ggacgcctca tgggggctag ggctggtatc
     9961 ggtggtactt atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat
    10021 aaggacctag aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc
    10081 acttctgctc atggaaatat gtacggtgtc atcaaagaag ttttgaagat caatgaagac
    10141 ttgaatattg gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt
    10201 gtagaagaag ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atccataagg
    10261 aggtatttat gacgcactac gttgccaatc cagaggtggt cattctcggg ggtggcatca
    10321 tgggacaaga agctatcctc aaaccaaaga ttcgtgcagc cttgaaagaa gccttggttc
    10381 caagtttggc tgagaacaca agattagaat ttgctcatca tcaaaacact gctgatatgc
    10441 ttggagccta ctatcatttt aaaataaaat aaatttaata tttactttac taaattagtg
    10501 tattcttcct actttaatta gagaatgatt taagttctct ttaaaaatca aaagagtcta
    10561 ggataaaata gttctcaatc acaaaaaagc taaagatttc caattgtgga actctagctt
    10621 tttaattttg agtcgttctc ttattgtatt ttaggaggtt attggccata agtaccaatc
    10681 tcatgtcaat tctcacttga cgcttccctc tcagattaca tctcttgtaa cccaaacaag
    10741 cctttatctg cccaaagaca ggttccacat caatcttgcg ttgagcgaaa atctgtctac
    10801 cttggggaga taaaagcgcc tgacattctt tagctttcaa gttttgatag cgttcgttca
    10861 tatacagtcc cttttgaggg gctgattcag gttcgtcggc gtagtaaacc ttgatttttt
    10921 gttgaaagtc tgtctgtgtt ttctgatatt tggtatggtg aaaacgataa taccagccat
    10981 caggatgtgt atagctatcc tccttgtcat tatagtgcca attcgctaag tttctagctg
    11041 actgtttata gcctctcttt tgttccttat caaacatggc atatt
//
LOCUS       DAVBNZ010000065        11007 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000065 DAVBNZ010000000
VERSION     DAVBNZ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.065"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(128..1759)
                     /locus_tag="VQ860_001836"
     CDS             complement(128..1759)
                     /locus_tag="VQ860_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET3120220.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2052..6992
                     /locus_tag="VQ860_001837"
     CDS             2052..6992
                     /locus_tag="VQ860_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET3120221.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFVGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     AGEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVQAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQKP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHEISTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLDAKPNHPSGS
                     ALAPLLEKNKVLVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7082..8278
                     /locus_tag="VQ860_001838"
     CDS             7082..8278
                     /locus_tag="VQ860_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET3120222.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8414..8941
                     /locus_tag="VQ860_001839"
     CDS             8414..8941
                     /locus_tag="VQ860_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3120223.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9018..9374
                     /gene="glnR"
                     /locus_tag="VQ860_001840"
     CDS             9018..9374
                     /gene="glnR"
                     /locus_tag="VQ860_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET3120224.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9411..10757
                     /gene="glnA"
                     /locus_tag="VQ860_001841"
     CDS             9411..10757
                     /gene="glnA"
                     /locus_tag="VQ860_001841"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET3120225.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10847..10966)
                     /locus_tag="VQ860_001842"
     CDS             complement(10847..10966)
                     /locus_tag="VQ860_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET3120226.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         3512 a         2037 c         2414 g         3044 t
ORIGIN      
        1 tagaggtgta ctattctagt ttcaatatac tatatatctg cagaatactc tttcagtttc
       61 attcagccta gtcttgctta ggaaaaagta aaaagccatc caattatgat ggatagcttc
      121 ttggttctta gatttgttct gcaaaaacct tttcagcaag gttcatagcg tggtctgata
      181 cacgagtgta gtgtgagatg atgtcgataa agttgacccc agcttgtgtt gaacattcgc
      241 ctttgttgag gcgtttgatg tgggtttttc tgagaacacg ttctatctta ttgattgctt
      301 catgacgttc tacaagactg cgtgcttttt caatatcatt gttttccaca ctatccagag
      361 catctttgat aaagtcacta gtttggcggt aaacttcctc taattctttc aaggcggcat
      421 cagaaaattc aacatttttc cgttgaagat agtcagtcag attgagtaga gcctccgtgt
      481 ggtctccaat ccgttccaaa tcacgggagg aatcaaggat attggtaagc acttcacttt
      541 ctttttggct gagagcttcg cttgaaaggg caatgagata acgtgttaat tgctcatcga
      601 tggtgttaat tgcttcttcg gttttatgcc ctttttcagc aactttttca tccaagtcaa
      661 tgatgtactt ataggaaagg tcaaaggctt tagcagcgta gtttcctaag tgcaagagct
      721 ctttcttagc atttcctaga gcgatagatg gggcctgttt gatgaaatgt tcatcaagat
      781 ataagggttc gtatttgaca acctcgtcct ctccaggaat aatcttggtt acaaagtaag
      841 ccagagctcc gataaatgga aattggacaa tggtgttggt aatattaaag gttccgtgag
      901 caaaggcgat ggtcatttcc ggtgctagat ttagcgtagc ttcaaaccaa tgaatcagga
      961 cagtaaaagg aactagaaaa ataacgcaga caactgttcc gataacgttg aaggcaacat
     1021 gagctcctgc tacccgttta gctgcaatat tagcccctaa agaggcaatg atggctgtaa
     1081 tggttgtccc gatattgtca ccaaatagaa ctggcaaagc tccctgtagg tcaattagat
     1141 tgccggcgta gaggttttgt aaaatcccaa tggtagccga agaagcttga attagcaagg
     1201 tcaagccagt accgacaaag acacccaaaa caggattctt acttagctca atcatatagt
     1261 ccttaaagac ctgtaaatcc ttgagtggag ccattgcgcc gctcatgaga ttgagggcaa
     1321 aaaagatacc accgacacca aagaggatgc gtccgatatt attgactgtc cgattttttg
     1381 taaaaaagag acagacggca ccgataaaga gcataggtag ggcatagtta cctaatttaa
     1441 aaccgatgag aaaggatgtg acagttgtcc caatattagc acccatgaca atcccgatag
     1501 cctgacgtaa ggttaagaga ccggcactga ccaggccgac tgtaataact gttacaccag
     1561 aactagactg aattagagca gtcatcccaa taccaaccag aactccaaag aaaggattac
     1621 tagtatattt gtcaatgtaa aaacgaaggc gatctccagc agcttgttgc aaaccgtctc
     1681 ccatggtctt gatactatat aagaatagcc ccagaccacc taaaaagtga aataaaattt
     1741 cctgccaatt aatggacatt tctttttcct ccgaaaaata atcgcggaat atctcctatt
     1801 ttattttaaa ggataaaagt aaatctaaca agtgttaatg tcaagtttgt aaaagaaaat
     1861 tataattgat aagtgtatta tttttaagag tttttaacct tattttagat ttgtgaaaac
     1921 agctattgtt ttttgtctaa aaatgtttta ggataaaaat gtgattatca tggttctaga
     1981 gtttgataaa aaactacaga atataaagcg ctttcttgaa aacaacaaaa tcaatctttt
     2041 aggaggagaa aatgaagaat ccattttttg aaagacgttg tcgttacagt attcgtaagt
     2101 tatcagtagg agcctgctcg ctgatgattg gtgctgtttt atttgttggt ccagccttgg
     2161 ctgaagaaac tgcagttcct gaaaatagcg gagctaatac agagcttgtt tcaggagaga
     2221 gtgagcattc gaccaatgaa gctgataagc agaatgaagg ggaacatact agagaaaaca
     2281 agctagaaaa ggcagaagga gtagcgacag catctgaaac tgcagaagca gctagcgcag
     2341 ctaaaccaga ggaaaaagca ggtgaggtgg ttgcagaaac accatctgca gaagcaaaac
     2401 ctaagtctga caaggaaaca gaagcaaagc ccgaagcaac taaccaaggg gatgagtcta
     2461 aaccagcagc agaagctaat aagactgaaa aagaagtcca gccagatgtc cctaaaaata
     2521 cagaaaaaac attaaaacca aaggaaatca aatttaattc ttgggaagaa ttgttaaaat
     2581 gggaaccagg tgctcgtgaa gatgatgcta ttaaccgcgg atctgttgtc ctcgcttcac
     2641 gtcggacagg tcatttagtc aatgaaaaag ctagcaagga agcaaaagtt caagccttat
     2701 caaacaccaa ttctaaagca aaagaccatg cttctgttgg tggagaagag ttcaaggcct
     2761 atgcttttga ctattggcaa tatctagatt caatggtctt ctgggaaggt ctcgtaccaa
     2821 ctcctgacgt tattgatgca ggtcaccgta acggggttcc tgtatacggt acactcttct
     2881 tcaactggtc taatagtatt gcagatcaag aaagatttgc tgaagctttg aagcaagacg
     2941 cagatggtag cttcccaatt gcccgtaaat tggtagacat ggccaagtat tatggctatg
     3001 atggctattt catcaaccaa gaaacaactg gagatttggt taaacctctt ggagaaaaga
     3061 tgcgccagtt tatgctctat agcaaggaat atgctgctaa ggtaaaccat ccaatcaagt
     3121 attcttggta tgatgccatg acctataact atggacgtta ccatcaagat ggtttgggag
     3181 aatacaacta ccaattcatg caaccagaag gagataaggt tccggcagat aacttctttg
     3241 ctaactttaa ctgggataag gctaaaaatg attacactat tgcaactgcc aactggattg
     3301 gtcgtaatcc ttatgatgta tttgcaggtt tggaattgca acagggtggt tcctacaaga
     3361 caaaggttaa gtggaatgac attttagacg aaaatgggaa attgcgcctt tctcttggtt
     3421 tatttgcccc agataccatt acaagtttag gaaaaactgg tgaagattat cataaaaatg
     3481 aagatatctt ctttacaggt tatcaaggag accccactgg ccaaaaacca ggtgacaaag
     3541 attggtatgg tattgctaac ctagttgcgg accgtacgcc agcggtaggt aatactttta
     3601 ctacttcttt taatacaggt catggtaaaa aatggttcgt agatggtaag gtttctaagg
     3661 attctgagtg gaattatcgt tcagtatcag gtgttcttcc aacatggcgc tggtggcaga
     3721 cttcaacagg ggaaaaactt cgtgcagaat atgattttac agatgcctat aatggcggaa
     3781 attcccttaa attctctggt gatgtagccg gtaagacaga tcaggatgtg agactttatt
     3841 ctactaagtt agaagtaact gagaagacca aacttcgtgt tgcccacaag ggaggaaaag
     3901 gttctaaagt ttatatggca ttctctacaa ctccagacta caaattcgat gatgcagatg
     3961 catggaaaga gctaaccctt tctgacaact ggacaaatga agaatttgat ctcagctcac
     4021 tagcaggtaa aaccatctat gcagtcaaac tattttttga gcatgaaggt gctgtaaaag
     4081 attatcagtt caacctcgga caattaacta tctcggacaa tcaccaagag ccacaatcgc
     4141 cgacaagctt ttctgtagtg aaacaatctc ttaaaaatgc ccaagaagcg gaagcagttg
     4201 tgcaatttaa aggcaacaag gatgcagatt tctatgaagt ttatgaaaaa gatggagaca
     4261 gctggaaatt actaactggc tcatcttcta caactattta tctaccaaaa gttagccgct
     4321 cagcaagtgc tcagggtaca actcaagaac tgaaggttgt agcagtcggt aaaaatggag
     4381 ttcgttcaga agctgcaacc acaacctttg attggggtat gactgtaaaa gataccagcc
     4441 taccaaaacc actagctgaa aatatcgttc caggtgcaac agttattgat agtactttcc
     4501 ctaagactga aggtggagaa ggtattgaag gtatgttgaa cggtaccatt actagcttgt
     4561 cagataaatg gtcttcagct cagttgagtg gtagtgtgga tattcgtttg accaagccac
     4621 gtaccgttgt tagatgggtc atggatcatg caggggctgg tggtgagtct gttaacgatg
     4681 gcttgatgaa caccaaagac tttgaccttt attataaaga tgcagatggt gagtggaagc
     4741 tagctaagga agtccgtggc aacaaagcac acgtgacaga tatcactctt gataaaccaa
     4801 tcactgctca agactggcgc ttgaatgttg tcacttctga caatggaact ccatggaagg
     4861 ctattcgtat ctataactgg aaaatgtatg aaaagcttga tactgagagt gtcaatattc
     4921 cgatggccaa ggctgcagcc cgttctctag gcaataacaa ggtacaagtt ggctttgcag
     4981 atgtacaggc tggagcaact attaccgttt atgataatcc aaattctcaa actccgctcg
     5041 caaccttgaa gagcgaagtt ggaggagacc tagcaagtgc accattggat ttgacaaatc
     5101 aatctggtct tctttattat cgtacccagt tgccaggcaa ggaaattagt aatgtcctag
     5161 cagtttccgt tccaaaagat gacagaagaa tcaagtcagt cagcctagaa acaggaccta
     5221 agaaaacaag ctacgccgaa ggggaggatt tggaccttag aggtggtgtt cttcgagttc
     5281 agtatgaagg aggaactgag gacgaactca ttcgcctaac tcacgcaggt gtatcagtat
     5341 caggttttga tacgcatcat aagggagaac agaatcttac tctccaatat ttgggacaac
     5401 cagtaaatgc taatttgtca gtgactgtca ctggccaaga cgaagcaagt ccgaaaacta
     5461 ttttgggaat tgaagtaagt cagaaaccga aaaaagatta cctagttggt gatagcttag
     5521 acttgtctga aggacgcttt gcagtggctt atagcaatga caccatggaa gaacattcct
     5581 ttactgatga gggagttgaa atttctggtt acgatgctca aaagactggt cgtcaaacct
     5641 tgacgcttcg ttaccaaggt catgaagtca actttgatgt tttggtatct ccaaaagcag
     5701 cattgaacga tgagtacctc aaacaaaaat tagcagaagt tgaagctgct aagaacaagg
     5761 tggtctataa ctttgcttca ccagaagtaa aagaagcttt cttgaaagca attgaagcgg
     5821 ccgaacaagt gttgaaagac catgaaatta gcacccaaga tcaagtcaat gaccgactta
     5881 ataaattgac agaagctcat aaagctctga atggtcaaga gaaatttaag gaagaaaaga
     5941 cagagcttga tcgtttaaca ggtgaggttc aagaactctt ggatgccaaa ccaaaccatc
     6001 cttcaggttc tgccctagct ccgcttcttg agaaaaacaa ggtcttggtt gaaaaagtag
     6061 atttgagtcc agaagagctt gcaacagcga aacagagtct aaaagatctg gttgctttat
     6121 tgaaagaaga caagccagca gtcttttctg atagtaaaac aggtgttgaa gtacacttct
     6181 caaataaaga gaagactgtc atcaagggtt tgaaagtaga gcgtgttcaa gcaagtgctg
     6241 aagagaagaa atactttgct ggagaagatg ctcatgtctt tgaaatagaa ggtttggatg
     6301 aaaaaggtca agatgttgat ctctcttacg cttctattgt gaaaatccca attgaaaaag
     6361 ataagaaagt taagaaagta tttttcttac ctgaaggcaa agaggcagta gaattggctt
     6421 ttgaacaaac ggatagtcat gttatcttta cagcaccaca ctttactcat tatgcctttg
     6481 tttatgaatc tgctgaaaaa ccacaacctg ctaaaccagc accacaaaac aaagtccttc
     6541 caaaacctac ttatcaaccg gcttctgatc aacaaaaggc tcctaaattg gaagttcaag
     6601 aggaaaaggt tgcctttcat cgtcaagagc atgaaaatgc tgagatgcta gttggggaac
     6661 aacgagtcat catacaggga cgagatggac tgttaagaca tgtctttgaa gttgatgaaa
     6721 acggtcagcg tcgtcttcgt tcaacagaag tcatccaaga agcgattcca gaaattgttg
     6781 aaattggaac aaaagtaaaa acagtaccag cagtagtagc tacacaggaa aaaccagctc
     6841 aaaatacagc agttaaatca gaagaagcaa gcaaacaatt gccaaataca ggaacagctg
     6901 atgctaatga agccctaata gcaggcttag ccagccttgg tcttgctagt ttagccttga
     6961 ccttgagacg gaaaagagaa gataaagatt aaatatcgaa aaatcttgtg aaatctttcc
     7021 ttatatttcc aaagtgtgat ataatagttt cgaataaaat aaataaagga gtttttgtaa
     7081 catggcaaaa cttactgtta aagacgttga cttgaaaggt aaaaaagtcc tcgttcgtgt
     7141 tgacttcaac gtaccattga aagatggcgt aatcactaac gataaccgta tcacagcagc
     7201 tcttccaact attaagtaca tcatcgaaca aggtggacgt gcaattcttt tctctcacct
     7261 tggacgtgtg aaagaagaag ctgataaagc tggtaaatca cttgctcctg tagcagctga
     7321 cttggcagca aaacttggtc aagatgttgt tttcccaggt gtcactcgtg gtgctgaatt
     7381 ggaagcggca atcaacgctc ttgaagatgg acaagttctc ttggttgaaa acactcgtta
     7441 cgaagatgtt gacggcaaga aagaatctaa aaacgatcct gaacttggta aatactgggc
     7501 atcacttgga gatggtatct tcgtaaacga tgcattcggt acagctcacc gtgcacacgc
     7561 atctaacgtt ggtatctcag caaacgttga aaaagcagtt gctggtttcc ttcttgaaaa
     7621 cgaaattgcc tacatccaag aagcagttga aactccagaa cgtccattcg tggctatcct
     7681 tggtggttca aaagtttcag acaagatcgg tgttatcgaa aacttgcttg aaaaagctga
     7741 taaagtcctt atcggtggtg ggatgactta cacattctac aaagcacaag gtatcgaaat
     7801 cggtaactca cttgtagaag aagacaaatt ggatgttgcg aaagctcttc ttgaaaaagc
     7861 aaatggtaaa ttgatcttgc cagttgactc aaaagaagct aacgcatttg ctggttacac
     7921 tgaagtgcgt gacactgaag gtgaagcagt ttctgaaggc ttccttggtc ttgacatcgg
     7981 tccaaaatct atcgccaaat ttgacgaagc tttgactggt gccaaaacag ttgtatggaa
     8041 cggacctatg ggtgtatttg aaaacccaga tttccaagct ggtacaatcg gtgtgatgga
     8101 cgctatcgtg aaacaaccag gagttaaatc aatcatcggt ggtggtgact cagctgccgc
     8161 agcgattaac cttggccgtg cagacaagtt ctcatggatt agtacgggtg gtggagcatc
     8221 aatggaactt cttgaaggta aggttcttcc aggacttgca gccttgacag aaaaataaga
     8281 ttttataaat aaatcaaaga agagagggat gaaagttcct cttttctttt gcttaaaata
     8341 aaaacgcttc ctctcaacta ttactcataa aaatcaccga tttatgataa aatggaaata
     8401 gaaagttgag attatgagtt attttaaaaa atataaattc gataaatccc agttcaaact
     8461 tggtatgcga acctttaaaa caggtattgc tgtttttcta gttctcttga tttttggctt
     8521 ttttggctgg aaaggtcttc aaattggtgc tttgacagcc gtttttagcc tgagggagag
     8581 ttttgatgag agtgttcatt ttgggacttc gcgtattcta ggaaatagta tcggtggact
     8641 ctatgccttg gtcttcttct tattaaatac ctttttccat gaagcctttt gggtgacctt
     8701 ggtagttgtt ccaatctgca ccatgttaac cattatgaca aatgtagcca tgaataacaa
     8761 agcaggggtt attggtggtg tagcagctat gttaatcatt accctatcaa ttccaagtgg
     8821 tgagacaatt tcgtacgtgt ttgtgcgtgt atcagaaacg tttatgggag tttttgtcgc
     8881 aattatcgta aattacgata ttgatcgtat tcgtctcttt ttagagaaaa aagaaaaata
     8941 atgttacatt ttataacatt atcaattgac gtttgtcttt ttttagacta taatagacag
     9001 aaagaaggaa attgtaaatg aaggaaaaag aatttcgccg aaatatggct gtttttccta
     9061 tcggcagtgt tatgaagttg accgatctat cggcgcgtca gattcgttat tatgaagatc
     9121 aagagttgat caagcccgat cgaaacgaag gaaatcgtcg catgtattcc ttgaatgaca
     9181 tggatcgtct gcttgaaatc aaagattata tctctgaagg ttataatatc gctgccatta
     9241 agaaaaaata tgctgaacgt gaagcgaaat ccaagaaagc ggttagtcag actgaagtac
     9301 gtcgtgcact tcacaatgaa ctcctccaac aggggcgttt tgcttcagta cagtcacctt
     9361 ttggtcgcgg ttaggcaacc gcaagtagtc atagattaag gagaaaactt atgccaatca
     9421 cagctgcaga tattcgtcgt gaagtcaagg aaaaaaatgt tacctttatt cgtcttatgt
     9481 tctcagatat tttgggaacc atgaaaaacg tcgaaattcc tgctacagat gaacagttag
     9541 ataaggtctt gtcgaacaag gttatgtttg atggatcttc tattgaaggt tttgtacgta
     9601 tcaatgagtc ggatatgtac ttgtacccgg acttggatac atggacagtc ttcccttggg
     9661 gagatgaaaa tggaagtgtt gcaggtctga tctgtgatgt ctatacaaca gaaggtgaac
     9721 catttgcggg tgaccctcgt ggtaatttga aacgagctct tcgtcacatg gaagaagttg
     9781 gattcaaatc cttcaacctt ggtccagagc cagaattctt cctatttaag ttggatgaaa
     9841 atggggaccc aacacttgaa gtgaatgaca agggtggcta ctttgatttg gcacctactg
     9901 accttgcgga caacacacgt cgtgagattg tgaatgtctt gaccaaaatg ggatttgaag
     9961 tagaagcgag tcaccacgag gttgcggttg gacagcatga gattgacttt aagtacgatg
    10021 aagttctccg tgcttgtgat aagattcaaa tctttaaact tgttgttaaa accattgctc
    10081 gcaaacacgg actttacgca acatttatgg cgaagccaaa atttggtatt gctggctcag
    10141 gtatgcactg taatatgtcc ttgtttgatg cagaaggaaa taacgccttc tttgatccaa
    10201 atgatccaaa aggaatgcag ttgtcagaaa cagcttacca tttcctaggc ggtttgatca
    10261 agcatgctta caactatact gccatcatga acccaacagt taactcatac aaacgtttgg
    10321 ttccaggtta tgaagcgcct gtttacattg cttgggctgg tcgtaaccgt tcgccacttg
    10381 tgcgcgtacc tgcttcacgt ggtatgggaa ctcgtcttga gttgcgttca gtggatccaa
    10441 tggcgaaccc ttacattgct atggctgttc ttttggaagt tggtttgtat ggtattgaaa
    10501 ataaaatcga agcaccagct cctatcgaag aaaatatcta catcatgaca gcagaagagc
    10561 gcaaggaagc tggtattaca gaccttccat caactcttca taatgctttg aaagctttga
    10621 cagaagatga agtggttaaa gctgctctcg gagatcacat ctacactagc ttccttgaag
    10681 ccaaacgaat cgaatgggca agttatgcaa ccttcgtttc acaatgggaa attgataatt
    10741 atttagacct ttactaatat agaagaaaga ttgcctgtgg gtaaacagtc acacagcagt
    10801 ctaagccatc aaatacctat aacccttaaa atagcgattt cggtcgctat ttatttttcg
    10861 aaaaatcctc ttgactcttt tgcgaattag atttatcatc agacgtgtag aagaaaatca
    10921 aggagtcact atggaaaaat tcaatttcaa aaacaatatc gggcaagaaa acaagttact
    10981 tcaaatcgaa atctacaagt ttactaa
//
LOCUS       DAVBNZ010000066        10754 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000066 DAVBNZ010000000
VERSION     DAVBNZ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.066"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(117..1541)
                     /locus_tag="VQ860_001843"
     CDS             complement(117..1541)
                     /locus_tag="VQ860_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3120227.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ860_001844"
     CDS             complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ860_001844"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET3120228.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ860_001845"
     CDS             complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ860_001845"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET3120229.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6527..7705)
                     /locus_tag="VQ860_001846"
     CDS             complement(6527..7705)
                     /locus_tag="VQ860_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3120230.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQTIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7785..8648)
                     /locus_tag="VQ860_001847"
     CDS             complement(7785..8648)
                     /locus_tag="VQ860_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3120231.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8651..10552)
                     /locus_tag="VQ860_001848"
     CDS             complement(8651..10552)
                     /locus_tag="VQ860_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3120232.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRTILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEQTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKVTAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3220 a         2371 c         1916 g         3247 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaatccct
      181 tgcactccag ctccagaacc tttgacacca aggaacggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa tttcttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg caaataagcc gcacgttcaa ttgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaaccacaa ccctttttgc gaaatttttg
     1621 agattatttt cacaagcttg atttttcaaa gtatactcaa taaaaataaa aaaatccact
     1681 acgtcaaggc gaggctaatg tggtttgaag aaattttcga agagcgtgaa tgagtatcat
     1741 ctatagtaaa ataaaaaaac tgaacaattt ggtttgggac agtcaaacca atttctcaca
     1801 atgttttaga aacacgggtg tgctattcca atttcaggct actataactg tcatagattg
     1861 ctgaaacaaa gtctaggtaa aagtcttcat aataaaaaga cctcctatca aatgttcaaa
     1921 aactttgata ggaggtcttg tttcgtgaaa atatttatca aattttctat acaagtgagc
     1981 tgttagccag gttctttcta ttctttcaat ttcaatgaat ggatttttta ccaatactca
     2041 taactgggaa tttttctgtg taaaaatagc gagatagatg gtatttataa aacactcaag
     2101 acagctagac taatatcatt taaaacatta tcttcttttg agcgactgtt ggttaccaac
     2161 atagctaaat ttcctgcatt ttcaaattga tagggttctg atttagcatt cacaaccacc
     2221 aagaggtgtt ctttgccgtg aacttcatag ataaggcagc cgctatgttc aatcgccgaa
     2281 tgcacaaaga catgatggta aatttcatca tagctagagt aagaaaaggc accagttttt
     2341 gtcttcaatc ggatgacttg acggataaac tcaatactgt cttgacgctc attaatcaag
     2401 ttccagttca cttggttcac actgtcagga gcattatagc tattcatcgc acgctctcta
     2461 tcatcatggg tcaactcacc attttcacca gtcgcaacca gtttggtacg accaaattct
     2521 tgaccgattt ccataaaggc catcccctgc atgagcagat tcatggctgt ggcagtttcg
     2581 accttgcgca tgatttgctc tgaactttgg tctggatgaa gggttgccaa taaatcgtga
     2641 agattgtaat tgtcatgggc ttctacatag ttaagcacct gatttggatg tgtatagctt
     2701 cctaattcac gacttcctag gattgcttta gctagaattg gctctgtcgc agcaccactg
     2761 acaaaacctg acttgatagc accataaact tctccccctt tgacagcatc gcgctgattg
     2821 tcattaaaga aaccaatatt tggcatctgg taggcattgt ccttcttggc cttatcataa
     2881 ggggcaagac ctgttcccat atcccatcct tctccataga ggataatgtt ggagtcgatt
     2941 tcatccaagc tttgacgaat catctgcatg gtcttgacat catgaatccc catcaagtca
     3001 aaacggaagc cgtcaatatt atattcctgc acccagtata gaagagaatc aatcatatac
     3061 ttgcgaaaca tttcgtgttc actggctgtt tcatttccaa cacccgttcc attctggaag
     3121 gtaccatctg gattcatacg ataatagtaa tcagggactg ttgtttggaa tggtgcatca
     3181 acaactgaga aggtatggtt atagactaca tccataatga ctccaatacc cgcatcgtga
     3241 taagcttgaa ccatcacctt caaatcacga atgacctgag ctggatcatc tggattagtt
     3301 gaaaaactag tttctggcgc gttatagttt tgtggatcat aaccccagtt gtaggttaca
     3361 tttccatcct catcgtattc tttatgacgg tctgcaattg gttgcaattg aacataattg
     3421 tagcccagct tcttgatgta atcaaaagca gttgactggc cgtattggtt aactgttcca
     3481 gcctgagcag cacccaagaa agttcctcga agatgttcat ctacacccga tgtaggtgat
     3541 ttagtcaaat cacgaatgtg catttcacag ataactgcct tacatggatt ttccaagcgc
     3601 caagtagcct ccgaaccgtg cttaacctcg aagttttcaa cttgcttttc tacatggctc
     3661 agaatagctg aacgtttgcc atcagggctg gtcgcgattg tataaggatc acgtgtcagt
     3721 gtttggtgat gagggaattg gacttgatac tgataagcct tacctaccaa atcttcctca
     3781 acatccaaac tccagacacc gattgtattg tccttatgat tataagagta gctattgcct
     3841 cttttcatct caaaagtctt ccaaacgggt gcatcattag cagctgattc ataaacgaca
     3901 acttgcactt ctgtcgctgt aggtgaccag agggaaaaat gagcctgatt gtcctctaca
     3961 cggcaaccca attctccttg gtaaccccaa tgatggtcaa aactagcact gttaatggcc
     4021 ttatcaaagg caaaaggatt ttgattttta tagaaaggac tggcaatagc aggattttca
     4081 gagtaataaa tcctatcatc gccttccaaa atccagactt ctgttaatag gggatagtga
     4141 ttaaaacgga tagaatattc tttactagtt tgacctgtat gaaccacaaa attcaagctt
     4201 tctataacat gtgaacttgg gtgttcaaag ctaaataaag ctccaaaata atcttctttg
     4261 taggttagca aatcaattcg ttgatcctga ctttttacaa aggagcaagt gtcatattca
     4321 ccattcttgc gatggtaatg aatgcgcata gggtagttat acatttttta tttttccttt
     4381 ttactttgtt tctatttcac taataaattt ttgtcaatct cgtctcaatt aacagacata
     4441 gtcatattct ctaaactctg tttttaaacg atccattaca aactttctag ccatgcctca
     4501 tctctgacct ggataccaag ttcttgtgct ttttgcagtt tacttccagc gtctgcacct
     4561 accacgacga ggtcggtctt tttagaaaca ctacctgtca ctttggcacc cagactttcg
     4621 agtttacttt tagcttctga gcgcttgagt cgttccaatt ttcctgtcaa taccacggtc
     4681 aaacctgaca aggccgcatc cgctactacc gtctgtcctt tatagtccag attgacccca
     4741 gtttctttca attctctgag cagaatttca gagccttctg tcgcaaaata agtctgaaga
     4801 cttttggcaa tcacgccacc tagactttca atactagcca cttcctctga atctgcctga
     4861 tacagatttt caattgaatg gaaatattga agtaaaagct gactagcctt gcttccgaca
     4921 tgacgaattc ccaaaccaaa taagagcttc tcggcagaat tttcctttga tgcttggata
     4981 gcctgataca gtttagcagc ggacttttcc ttaaccccct ctaaaaggag gaaatcctct
     5041 tcttgcaaac gataaatatc cgccacatcc ttgactaaat tagcagcaaa aagcttctca
     5101 acaatagatg gaccaaggcc tgtaatattc atagcatcac gagaagcaaa gtgaatcaag
     5161 ccttccatga tttgagcagg gcaacgcgga ttgatacaac gtagggccac ttcatcttca
     5221 aagtgcaaca agtcagagtt acaacttgga cagtttgtag ggatatctag tttttcttca
     5281 gaaacccgtt tggactctac cacacgtaaa acggcaggga tgatgtcacc agccttatat
     5341 acaatgaccg tatcgtcttt tcggatatct ttttcagcaa tataatctac attgtgcagg
     5401 gtcgcacggc taacagtcgt accggcaagt tgtactggtg ttagattagc agttggagtt
     5461 acaacaccgg tacggccaac tgtccagtca actgataaga gttgagcttc tttttcttca
     5521 gcagggaact tgtaggctac tgcccacttt ggagccttaa cggtaaaacc aagttcttct
     5581 tgacttgcta ggtcgttgac cttgattacc actccatcaa tatcgtaagg tagattttcc
     5641 cgttcctgtc ctacttcttg gataaaattc cagatttcat ctatgttttc agccaagatt
     5701 cgcttaggat tgaccacaaa acctagttgt tctaggtact tcaaaccctt ttcttggcta
     5761 tcacgagttg aaggactggc ttcttgatag agaaacgttg caagattacg ctttgcaact
     5821 actgctgtat ccaactgacg cagagttcct gctgccgcat tacgaggatt agcaaattca
     5881 ggctctccat tttcttggcg cgcttggtta acttggtcaa aggaagcgcg tggcatgtaa
     5941 cattccccac gaactgtgat atctagttct tctggcaaag tcaaagggat gtccttaaca
     6001 cgcttgaggt tttctgtgat attttcacca attgaaccat ctccacgtgt taccccagca
     6061 accaaaatcc ccttttcata agtcagcgag atagataagc catcgatttt cagctcacaa
     6121 atataggtcg gatgagccac ttccttacga acacgcgcat caaaagcatc tagctcctca
     6181 cgtgaaaaag catcctgcaa actataaaga ggatactgat gactgtattt ttcaaaacca
     6241 tctaaaacct tgccaccaac acgatgagtc ggactgtctg ctagcacttg ctctggataa
     6301 gcagtttcta actcgaccaa ctcacggtaa aggcggtcat actcactgtc tgaaaccgag
     6361 ggattatcgc tggtatagta ctcagtcgca tagcgattga gcaaagcgac taactcattc
     6421 attcttttat tcataagacc attttaccat aaaacaagcc ctcctcacaa acgagaaggg
     6481 cggaaaaaac acttagtttg aaattatttt tgaaactcaa gcaaccttat atcaattttt
     6541 caaaatgagt tcgaacataa ataaacgata tacaagacaa gatgataaca ccacttccaa
     6601 ttatcaggaa agaagagaga tgtacacttg gcaagactgt cataaatcct tttgcaatag
     6661 gcataaatag aatagctaag gtaaaaattg tactcagtac tctcccaaga aattcgctct
     6721 caaccttggt ttgtacttga gtaaaaaagt gaatattaaa aatcgtcata aacaattcac
     6781 aaactaaatt tccagaaaag gaaagaaaag ttggaagtgg taatcccatc ataaaaactc
     6841 cgacacctgt caaagccagt aaaatcaaaa gattataaat attagcttta attttactag
     6901 ctagaagagc cccaatgatg gaaccaatag cccccatagt taaaatactt gcataggctc
     6961 cttctgaccc gtaaagctga ttcgaaaagg gaagtagaaa ttcaaaagct gcaaaaaaga
     7021 aattaacgct ggaagctacc agcaaaagga agaaaatttc ttgctgatgc cagatatagt
     7081 gtaacccatc cttgatatct acaaaaatat ctctcccagt aaaagccttt ttctcttgaa
     7141 cttttgcttc ctcttttgga aggaaagcca ctagaacaaa agcaatgaaa aaagtcagcg
     7201 agtctagcag tagcgtcata tggagacttg caaactgtaa aacaaggaag gaaagaacag
     7261 gagagctaac acctacaacc tgcaaaacca gctctaagcg agaattatag atcacaatct
     7321 catctttctc caccacttca gttatgatag ctttattggc tgtgcgagaa aaggcaaaag
     7381 caatagtctg cacaatgtta gcaacaatca aagcgccaat catccagcta tcattcctta
     7441 tgaaagaaat agccagacaa agaatcccac aaacaagatc tgccgtcatt aaaatcttac
     7501 gacgagaaaa acggtctgaa ataactccgc caaagggatt gacgagaata gatgtgacga
     7561 gctcagaaat ctgatacatt cctaaaactg tctgtcctat agtccccata gaagccaacc
     7621 agacactatt tccataatca tagagcatat ttcccatttt attgatagcc ccacggctaa
     7681 tcaactgcac tgcatagcga ttcatattaa agctcctctc aaattttgaa actattgtat
     7741 caaaaccgaa aggagctttt tattttttcc cttatttggg aaaattaact tttgacaaat
     7801 ttttcgtagt gttcctgata ataggctact tgctctggaa gacctaacac atcaaaaata
     7861 tgcatggcct cttgcatctg cttacagcct tctttacact gtcctttttg atataaggcc
     7921 aaacctttta aataatggaa aacattacgc tcataaagct taataccttt gtcaataatc
     7981 ttctctgtat aagcctcaaa atagttggca ttataaaaag aagaatgctc taaacaatgc
     8041 tggtaacaat tgagggccaa aattaacact aatctcttat ggcgactaat ctcttggtaa
     8101 aattcctccc tctccataac ttctctacca atccgagtga catagtctac atcgtagaaa
     8161 ctatagaggt taccgaaaag aatcaactca tacatggtcc attcttctgt tttgaagaga
     8221 taatctgcta ccttatccaa atcatcctgc ttcatatcat aactcgcatc tctttgacaa
     8281 atcagacctt gtagcaaaat ccagttcagc tcaaaataaa ggggagtcgt cgaactctta
     8341 gacttttcaa gttgttctct ttgaagcttt tgaaaacctg caatatcgtt tgaatagtaa
     8401 agtgggataa tctgtgccat catagacaca tgttcatgat tatgaaaatt ccttgcctta
     8461 tccatgaaat tttcgattgt tacatgaatg ttatccaaaa tctcaaagaa acgggagact
     8521 gccaggtcag actccccaag ctcaaagcga gataactgag aggtagagca ggattcgcct
     8581 gctgcttcct ttaaagaata atttccactt gttcgaaatt cacgaaatac ttttccaaga
     8641 tgttccatct ttacacctgc tctgataatt cttcccactc aagcatagct tcttcctgac
     8701 gatggctgat tttgtccagc tcagcctgta attccatgag tttgtcggca tcgtttgttt
     8761 ccaacatttg ttcagaaatg gcttggcttt gactttctag ctcttcaatt tcagcttcta
     8821 gactttcgat ttgtcgcatg agtttgcgaa cttctttttg actttctttc tgggcctgat
     8881 agtcattgac tggacttgct tcctttgctt gattgctagt tgaagcttcc tcagtctgac
     8941 tcatttctgc tgttactttc ttctcaacat agtagtcgta atctccaagg tagagagttg
     9001 aaccattctc agacaattcc aaaacatgag ttgccacacg attgataaag taacgatcat
     9061 gactgacaaa aagcaaggta ccatcaaagt caatcaaggc attttctagc acttccttac
     9121 tatcaatatc caagtggttg gtcggctcat ccagaatcaa aaagttattg ttttccatag
     9181 acaatttggc taaaagcaaa cgagcttttt cgccaccaga tagcatgccg actgattttt
     9241 taacatcatc tcctgagaaa aggaaggctc caagacggtt gcggatttca acttctggtg
     9301 tcagtttgaa atcattccag agttcatcca gcaccgtatt acttggtgtc agcttgcttt
     9361 gggtttggtc atagtaacca acctcaacat tagcgccaaa gcgcttttct cccttgataa
     9421 acggaatttg atccacgatt gatttgataa aggttgattt tccgatacca ttgggaccaa
     9481 cgatagcgac agcattcatc ttacgaagat ctaggttgat aggttgtgac aagacttccc
     9541 cgtcataacc aatagcagta ttttcaacag tcaaaacaac attgcccgac gtttgttcag
     9601 actggaaggt catgttggct gctttcttgc cagcttcagg cttgtccaaa cgctccattt
     9661 tttctagttg tttacggcga gattgagcac gtttagtcgt tgaagcacga actagattgc
     9721 gattgacaaa gtcttccaga gcagcgattt ccttctgttg cttttcatag ttttttgcct
     9781 cagtaactag cttttgctcc ttcaattcga caaaacgaga gtaattcccc acatagcgat
     9841 ccaaggaatg cttggtcaaa tctagcgtaa ttgtcgcaac cttgtccaag aaataacggt
     9901 cgtggctgac gataatgagg gcaccgctat agtttaccaa gtaattctct agccaggcga
     9961 tggtttcaat atccaagtgg ttagttggct cgtccaagac caagagattg ggcttttcaa
    10021 ggagcatttt ggcaagtgcc aaacgagtat tttgaccacc agaaagctca gcaattttca
    10081 tctgccacat agactcgtca aacttgaatc cattcaaaat cgttcgaata tcagcttcat
    10141 aggtaaagcc acctgcttgg cgaaaattct cagataagcg gtcataatct gacatcagtt
    10201 tatccaaatc ctcaccagac ttttcaccca tctccagctc catctgacgc agttgtctct
    10261 ccgtccgacg caaattatta aagacatgaa gcatttcatc gtagatggta ttttcagact
    10321 caaaacggct atcttgggct aggtaagaca gagaaatatc ttttttctta ttgatttctc
    10381 cgctagttgg ctcctcttct ccaactaaaa tcttcaaaag agtagactta cctgcaccat
    10441 ttttcccaac aagggcaatc cgatctcgtt catcaacctg caggttgata ttatcgaaaa
    10501 gaacctctcc tgcaaaagaa cgttcaattt tattagcttg taaaataatc ataagagtag
    10561 tatagcatgt ttccctaagg cattcaagat aatcgtaagt cttttagtac aacttttata
    10621 acataaaata aactaaatta tgtatatttt atattagatt cttcactatc ttgttggatt
    10681 ttctaaccag ctaatcttgt ttcaaatagt tatcgcacaa gcctattatt taattctttt
    10741 cattatttac gtac
//
LOCUS       DAVBNZ010000067        10686 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000067 DAVBNZ010000000
VERSION     DAVBNZ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10686
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.067"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            85..366
                     /locus_tag="VQ860_001849"
     CDS             85..366
                     /locus_tag="VQ860_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET3120233.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGIDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            498..1442
                     /gene="manA"
                     /locus_tag="VQ860_001850"
     CDS             498..1442
                     /gene="manA"
                     /locus_tag="VQ860_001850"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET3120234.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1433..2937)
                     /locus_tag="VQ860_001851"
                     /pseudo
     CDS             complement(1433..2937)
                     /locus_tag="VQ860_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3042..3782
                     /locus_tag="VQ860_001852"
     CDS             3042..3782
                     /locus_tag="VQ860_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3120235.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAAYVQTNAE"
     gene            complement(3811..4266)
                     /locus_tag="VQ860_001853"
     CDS             complement(3811..4266)
                     /locus_tag="VQ860_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3120236.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4286..5461)
                     /locus_tag="VQ860_001854"
     CDS             complement(4286..5461)
                     /locus_tag="VQ860_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3120237.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDEVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5520..6365)
                     /locus_tag="VQ860_001855"
     CDS             complement(5520..6365)
                     /locus_tag="VQ860_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3120238.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6490..7047
                     /locus_tag="VQ860_001856"
     CDS             6490..7047
                     /locus_tag="VQ860_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3120239.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7066..7533
                     /locus_tag="VQ860_001857"
     CDS             7066..7533
                     /locus_tag="VQ860_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET3120240.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7622..8251
                     /gene="upp"
                     /locus_tag="VQ860_001858"
     CDS             7622..8251
                     /gene="upp"
                     /locus_tag="VQ860_001858"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET3120241.1"
                     /translation="MGKIEVINHPLIQHKLSILRRIDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8425..9015
                     /gene="clpP"
                     /locus_tag="VQ860_001859"
     CDS             8425..9015
                     /gene="clpP"
                     /locus_tag="VQ860_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET3120242.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAHETLEYGFIDEIMANNSLN"
     gene            9094..9342
                     /locus_tag="VQ860_001860"
     CDS             9094..9342
                     /locus_tag="VQ860_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET3120243.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9443..10603
                     /locus_tag="VQ860_001861"
     CDS             9443..10603
                     /locus_tag="VQ860_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3120244.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEVAEVVKP"
BASE COUNT         3385 a         2105 c         2278 g         2918 t
ORIGIN      
        1 tcttctttaa ttgatttcat attactattg tataatgatt tttgatttta gtttagtatt
       61 atcgtagaaa atggactcgg tgctatggat acaccggatg agaatggtta tgtagcagat
      121 gactatcgga ttacttactt agaggcccac atcaaggcca tgcgagatgc catttaccaa
      181 gatgggattg acttgcttgg ttatacgact tggagctgta tcgatccggt ttcagctggc
      241 acaggggaaa tgaataagcg ctatggcttt atctatgtag atcgagataa tgtaggaaat
      301 gggactctca aacgtagcaa gaagaagtcc ttctattggt acatgtcatt tatagcaatg
      361 gtgtaagcat cgagtagagc acatttgttt actattttta taaaatcttc tccctgcttt
      421 ataagatgta aaaaagagtt caaatggaac tctttttttg ctataatgag gggagaaaaa
      481 tcagacagga gattaagatg tcagaaccat tatttttaca atcagttatg caagaaaaaa
      541 tctggggtgg taccaagcta cgtgatgagt ttggctacga catcccaagt gaaaaagtcg
      601 gagagtactg ggctatctca gctcatctaa atggtgtttc taaagttgcc aatggtcgtt
      661 acgagggaac agatcttgct actttgtatg cggaacaccg tgaattattt ggcaatcgtc
      721 cggaacctgt atttccactt ttgaccaaga tcctcgatgc caacgactgg ctcagtgtcc
      781 aagttcaccc agacgatgct tatggactcg agcatgaagg cgaacttgga aaaacagaat
      841 gttggtacat cattgcagca gatgaaggtt cagagattat ctacggtcac aatgccaagt
      901 caaaagaaga actccgccag caaatcgagg ataagaactg ggatgcgctg ttgacaaaag
      961 tgccagttaa agcaggagat ttcttctatg taccaagcgg taccatgcac gctatcgggg
     1021 cgggtatctt gattcttgaa acccagcagt ctagcgatac cacttaccgt gtctatgact
     1081 ttgaccgtaa ggatgacaag ggcaatttac gtgaacttca ccttgaaaaa tctatcgatg
     1141 tcttgaacat tggtgaaccc gcaaatagcc gtccagtgac aatcaaagca gatgatctac
     1201 gttccactct ccttgtatcc aatgatttct tcgcagttta caaatgggaa attactggaa
     1261 aagttaactt tgaaaagaca gctgactaca gcttgttgag tgtcttggct ggtcaaggtc
     1321 aactaactgt tgacgggaaa aactatccaa tccaaaaagg gagacacttt atcctaccaa
     1381 gtgatgttga agcttggact ctggaagggc aagatttaga attaattgtt agtcatccat
     1441 aaaaaagaaa gggcctgagt tcattactca agtccttttg attacataaa ttgggcgatg
     1501 aagaccacga tgatgattgg aatgacggaa cgaagaaacg aagaaggaag agccagactt
     1561 ggaacagtcc ttgtttccat gctctttcat cgagatggag ttcctccatt gcaagagcct
     1621 ttttaaagat atagcctgta aaaagtgaaa ggaagagagc tccaaatggc atgaggagat
     1681 tggaaaccaa gaagtccata gcgtcaaaga aggtcttacc aaaaatgtga acatccgcca
     1741 tgacaccgta agatagggct gaaggaatgc caaagacaaa ggtcaaaatt tctaaaataa
     1801 cactccattt agcacgcttg ctgttgtcct gattggtgat attgtctaca ttgatttcta
     1861 gcatcacgac agaagaagtg acagtcgcaa agaggaagag gacgtagaaa atggttccaa
     1921 aaggcatctt gtcaaagagt tgaggcaaga cgataaagag caggctgggt cccccttcag
     1981 actggatatt gaagggggat cgagcttgga aaatggctag acctgccatg atggatatcg
     2041 agatattcat ggctacgatg gagattcctg actggactag attggttttc ttgtccaagt
     2101 aagaagcata ggtcaacatg actgtaaccc ctagtgagag ggcaaagaaa gattgtccca
     2161 gagcatagag gagaccagcg ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa
     2221 ccccttccat ggcatttggc aaactgagag agcgaccgat gataaaaaca aagacgataa
     2281 agagcagggg catcatgact ttcgaagctc tttcaatctc tttttgaacc ccacgtgata
     2341 caatgaagat attcaatagg ataaaggccg cttgagctcc tagggcaatg gctggatttg
     2401 aaatgattga agtaaataac tgagcataat cacccgttcc accaagttgg aacaatttcc
     2461 caaactcaat acctagatag actagaatcc atcctccgat aacactgtaa aaagataaga
     2521 ggataaagag ggcaaaggcg ccaatccaac cgataaagtt gtacttgtta ttcttgccca
     2581 gttttccaaa ggttttgata gcggaaacgc cagcactacg gccaagggca aactcagcca
     2641 gcaggagagg gaaaccgatt aaaatagtgg aaatgagaaa gattagtaaa aagcctccac
     2701 cgccattagc agcagtcatg tagggaaact tccaaacgga accaagcccg atggccagcc
     2761 agcagatgct agaataaaac caagtttcga cccccattgt gatttttctg acatagttaa
     2821 actctgatct cctttttcaa aataagaaaa agctacttga gttgtcaaat agccttctgt
     2881 ttgattgata gacttgacta tcctatcatg ttttctaagg tctgtcaaga aaatcatttt
     2941 caagttttca cacctttctc aaaaaagtta aaaaattttc tcaaaaacgc ttgactctga
     3001 cctaagggga ggggttatac tatcattgta aggaggaaat catgtaccat ataaaagaag
     3061 ctgcgcagct ttcaggtgtc tctgtcaaga ccctgcatca ctatgacaag ataggactct
     3121 tggtcccctt aaagtcggaa aacggctatc gaacctacag tcaagaggat ttggaacgcc
     3181 ttcaggttat tctttactac aaatatctag gcttttcttt agagaaaata gcagagctgt
     3241 taaaggaaga aaggacagat ttattgcccc atttgactag gcagttggac tatctaactc
     3301 gcgaaaggca acatctggat accttgattt ccaccttgca aaaaactatt caagaacaaa
     3361 aaggagaaag aaaaatgacc attgaggaaa aattcacggg atttagctat caagacaatc
     3421 aaaaatacca ccaagaagcg gtagagaaat atggtcaaga agtcatggga caagcgctcg
     3481 aacgccaaaa aggtcacgaa gacgaggcta cggccgcctt taaccaagtc tttcaaactt
     3541 tggcacaaaa tcttcaagtt ggtttacctg caacagcaac cgaaaaccag gagcaagcag
     3601 ccaagctctt gcaagccatt cgcacttatg gatttgactg ctctattgag gtattcggtc
     3661 atatcggtaa aggttacgtc tacaacccag agtttaagga aaacattgac aagtttggtt
     3721 ctgaaacagc ccagtacacg tcagatgcca ttgcggctta cgttcagaca aatgcagaat
     3781 aaataggcta ggaatttcct agcctatttt ttacttcaaa tcataaagcc agtcgtcacc
     3841 gtttttgtag taaaagaatt cactgagatc ttcttctaga aacacacgaa gcatatcaga
     3901 catatcatcg gttgcaagtt ttagatgaga aagattttca aagtcctccc accaaacttt
     3961 cccttcgtct gaagactgga gttcaccagt aaagtgttct gtcttgtaaa aaaggacgac
     4021 ataacgataa tccttgtcgt cataccagtt tttgatacca cagagttggg gtttggaaat
     4081 gatcagacca gtttcttctt tcacttcacg aatgacagca tcgacaaagg attcgccacg
     4141 ttcaacatga ccaccaggaa aagtaatgcc agaccagtcg ggactaactc ggtcttggac
     4201 caggacctta tctccgtttt taatcataca catgttaaca aattcgactg cctctcttct
     4261 gttcattctt cacaaccttt aatctttaat cataatgcag acttcccgcc acccagccgg
     4321 tacagagggc agaagtgatg ttaaagccac ccgtgtgggc attgatatcc ataacttcgc
     4381 ctgcaaagtg gaggccaggt accagcttac tttcaagggt tttaggattg atttccttga
     4441 gactgactcc acccttggta acaaaggact ttgcaaggga catttttcca gttacaggaa
     4501 ttttaagttc tttaatggac tggacaagtt gttctcgttc cttttcagtc agttgtttga
     4561 ctttttcagg atatccttgt acaaaaaatt cggccaagcg ttctggtaac aaggttttta
     4621 aagcgttttt caaggatttt tcccgatttt cttctagaaa tgtaaccaag tccttctcag
     4681 aaagttgagg caaaacatcg agtgagagaa cctccccacc tttgacaaag ctagacatgc
     4741 gtagggcagc aggacctgac aaaccaaagt gggtaaagag taaatcatga gtgatgacat
     4801 gcttaccata acttagggtc acctcgtcca gagaaatccc ttgtaaggct ttatgtggaa
     4861 aatctgttaa taaaggactt tcagcagcct caagatcggt gatggtatgc ttaaaatggc
     4921 gagcaatctc gtgaccaaaa ccagtcgaac cagtcgaagg ataagactta ccacctgttg
     4981 tgacaatgag tttctcacaa gtgaaggttt gatccgctga cttaaggaca aactggttat
     5041 ctactttttt aacagaaacg atttctattt gagtagcaac ttgaccacct agttcggtga
     5101 ttttcttttc caaagcttcg ataatagtcc gagacttgtc actggctgga aagacgcgtc
     5161 cgtggtcttc gaccttaagt ttaacaccat tttctgtaaa aaagttgatg atgtcatgat
     5221 tatcgaactg ggagaaaaca ctgtaaagaa agcgtccgtt tccaggaatt ccagctagca
     5281 ggttgtctaa gctaccattg ttggtcacat tgcaacgtcc cccaccagtc ccagctaatt
     5341 tttttccaag tttccgattt ttttcgatga ggagggtttt ctgtccataa aagctactgg
     5401 aaatcgtagc catcatacca gcaggtcccc caccgatgac aatagtatca aaatgtttca
     5461 tagctctatt gtaccacaaa aaaacaagag atgatggtca cctcttgtca agaatgcaat
     5521 taatcaattt catagcccat cagcaaaccg ccctcttctg catagaaact gcagagacca
     5581 gaggttggta gaattttaat atccgcttgt gggaaggttt cacggattcg ctctgagagc
     5641 tgttgacaac atttttcgtt attgcgttgg gccatgacaa tacggccacc agcatatcca
     5701 gcttttacta actcatcata ggcagcttga actgatttct ttgatcccct tgctttttgt
     5761 agcaattcga gagttccagt ttcactagct tttccgacca tacgaatgtt gagaaggcca
     5821 acgaccgtac cgataagctt gctcaaacgg ccgttcttca ccaagttatc gactttggct
     5881 aggacaaaga gcaacttagt tttttcttga taggcagtga tagcttcaac cacttcttca
     5941 aaagacaagc cctggtcaat caagtcattc aatttttcta cgagtaggtc aacttcacca
     6001 ccagcagata aactatcaat cacatgaatc ttagtgtcag gatggtcttc cagataaata
     6061 ttctttgcta gttgagcact attgtgactg ccagaaaggg tacctgtgat ggttactagg
     6121 aaaatgtttt tggcaccttc aaatgctcgc aaatagtcat ctgggcttgg acaagctgat
     6181 tttgaagctt ctgcagttgc atacatggtt tccatcattt ggtcaatatc gagactggcg
     6241 tcatcaacaa agacctgatc agctacttga atggttaagg ggacacttac aaaggttgtg
     6301 ttaatagctg gtgttggcag ttgacgataa tcacaaccag agtcagcaat aatcttccaa
     6361 gtcatagaaa ttctccatct ttgtcagtta tacattgaca aaggttctgt ctttttttac
     6421 aattatatca tgaaaactct tgaaacaaaa gcatcatccg tctgttgtga caagtagaaa
     6481 gaaaatgtta tgtctgaacg tagaatctct gaaaagtctc ttgaaaatct cagaaaatca
     6541 aaccaagaat ccaatttatt aaccagagaa gccattgaaa cagccctctt gcaactcttg
     6601 gaaaaaaagg agctgaccaa gattagtatt tctgaattgg tcaaacgtgc aggtgtttcg
     6661 cgtgcggcct tttatcgcaa ttatgactcc aaagaggaaa ttttagagag cgtctttaaa
     6721 cgaactgtcc acaatattat ggaacagctg catcattacg atttaaagac agacctttat
     6781 ttggtttggg ttcacctttt ccgggaggcc agaaaggaag ctagagtaat tcaattggcc
     6841 ttggattacc atctggaaaa aatctttgtc caagccatgc aggaatttct agaaaaatac
     6901 catgggaaat caaaaggtgt cagctcttat cttcattcct tctggagctc agccatcgtc
     6961 tctgtccttc taaaatggat caaggatggc atgaaggtac cagctgaaaa gattgcagat
     7021 ttaggtttac cattttttaa aaaatagaga aaaaggagaa aagagatgac tgaaaaaaga
     7081 ctggcctggg atgagtattt tgcagcccaa gccctactaa ttgcgaatcg ttccacttgt
     7141 aaacgtgcta aagtgggcgc gattctggta aaagataata aggtaatttc cactggttac
     7201 aatggttcgg tgtcagggac tgagcattgt attgatcacg aatgtttggt cattgaaggc
     7261 cactgtgttc gcacccttca cgctgaggtc aatgctatcc ttcaaggtgc tgagcgtggt
     7321 gttcccaaag gctttacagc ctatgtaacc cattttcctt gtctcaactg tacaaaacaa
     7381 ttgcttcagg tcggctgcaa gcgcgtggtt tatatcaacc agtaccgaat ggacgactac
     7441 gcccaatacc tttatcaaga aaaagggaca gaattgaccc atttaccact tgagacagta
     7501 cagacagctc ttaaagaggc tgatctaatg taaaaattat caaaaataaa tggtttagaa
     7561 agatttttaa accgtttttt ggtataatga gaagaataaa ttgaaagaag gaattccaaa
     7621 aatgggaaaa attgaagtta ttaatcaccc actgattcaa cacaaattgt caatcttgcg
     7681 tcgtatagat acttctacaa aagcttttcg tgagctagta gatgagattg caatgttgat
     7741 ggggtatgaa gtacttcgtg atcttccact agaagatgtg gaaatcgaaa caccaattac
     7801 aaaaacagtt caaaaacaat tggcaggtaa gaaattggcc atcgtcccaa tcttgcgtgc
     7861 aggtatcggg atggttgatg gtctcttgag cttggttcca gctgctaaag ttggccacat
     7921 cggtatgtac cgtgatgaag aaacacttca accagttgaa tacttggtga aattgcctga
     7981 ggacattgac caacgtcaaa tttttgtagt agacccaatg ttggcaacag gtggctcagc
     8041 aatcttggct gttgattctc ttaaaaaacg tggcgcatca aatatcaaat ttgtctgcct
     8101 tgtatctgct ccagagggtg taaaagccct tcaagaagct catccagatg tagaaatctt
     8161 tacagcagcc ttggatgaac gtttgaacga acacggttat atcgttccag gtcttggaga
     8221 tgctggagac cgcttgttcg gtacaaaata agatcgaaaa gaagaatgac ttggaaaagt
     8281 atttccagtc acgaaaggag gttgggtttt tgtttctgtc taatgaaagc agagcaaaaa
     8341 tttgaccttt tttgaccaag atattataat agtcttatct tcagtcattt gaccaacaaa
     8401 attaaaactc aaaaggagaa atgaatgatt cctgtagtta ttgaacaaac aagccgtgga
     8461 gaacgttctt acgatattta ctcacgtctt ctcaaagacc gcatcattat gctgacaggt
     8521 ccggttgaag acaatatggc taactctgtt attgcccaat tgcttttctt ggatgcccaa
     8581 gatagtacaa aagatattta cctttatgtc aatacaccag gtggttctgt ttcagctggt
     8641 ttggcaatcg tagataccat gaactttatc aaggcagatg tccaaaccat tgttatggga
     8701 atggctgcat ctatggggac tgtcatcgca tcaagtggag caaaaggcaa acgtttcatg
     8761 cttccaaatg ctgaatacat gattcaccaa ccaatgggcg gtacaggtgg tggtacccaa
     8821 caaactgata tggctatcgc tgcagaacac ttgctcaaaa ctcgtaatac cttggaaaaa
     8881 atcttggctg aaaattcagg tcagtcaatg gaaaaagtcc atgcagatgc agaacgtgat
     8941 aactggatga gcgcccatga aacacttgaa tatggcttta ttgatgaaat tatggccaac
     9001 aattcattga actaatgatg atagaaggca aactcgactg ggtttgcttt ttttggtata
     9061 atagggagag atttcttaga aagaggattt atcatgtttg aaaaagtcaa tcgctctggc
     9121 ttgattatct atctttacta taatcgtgat gccaaaaaac tgcaggatta tggagatatt
     9181 acctatcatt ccaagaaaca tcgttactta caactctatg ttccaactca agaagtggag
     9241 caattggtcg gacgcttgag caaggaaaaa tttattaaaa aagttagggt ttgtcatatc
     9301 caagagttgg aaacaccctt tgtgggcaat ctttatcgat aggaaaacgt tatcatcgaa
     9361 aaagttcaag gaaaacattg acaattttct gataattcgg tatattctta acagactatt
     9421 taagaaataa ggagacaaaa agatgaagaa aaaatttgcc ctatcgtttg tggcgcttgc
     9481 aagtgtagca cttcttgcag cctgtggaga agtgaagtct ggagcagtca acactgctgg
     9541 taactcagta gaggaaaaga caattaaaat cgggtttaac tttgaagaat caggttcttt
     9601 agctgcatac ggaacagctg aacaaaaagg tgcccaattg gctgttgatg aaatcaatgc
     9661 cgcaggtggt atcgatggaa aacaaatcga agtagtcgat aaagataata agtctgaaac
     9721 agctgaggct gcttcagtta caactaacct tgtaacccaa tctaaagtat cagcagtcgt
     9781 aggacctgcg acatctggtg cgactgcagc tgcggtagcg aacgctacaa aagcaggtgt
     9841 tccattgatc tcaccaagtg cgactcaaga tggattgact aaaggtcaag attacctctt
     9901 tattggaact ttccaagata gcttccaagg aaaaattatc tcaaactatg tttctgaaaa
     9961 attaaatgct aagaaagttg ttctttacac tgacaatgcc agtgactatg ctaaagggat
    10021 tgcaaaatct ttccgcgagt catacaaggg tgaaatcgtt gcagatgaaa ctttcgtagc
    10081 aggtgacaca gacttccaag cagcccttac aaaaatgaaa gggaaagact ttgatgctat
    10141 cgttgttcct ggttactata atgaggctgg taagattgta aaccaagcgc gtggcatggg
    10201 aattgacaaa ccaatcgttg gtggtgatgg attcaacggt gaggagtttg tacaacaagc
    10261 aactgctgaa aaagcatcaa acatctactt tatctcaggc ttctcaacta ctgtagaagt
    10321 ttcagctaaa gctaaagcct tccttgacgc ttaccgtgct aagtacaatg aagagccttc
    10381 aacatttgca gccttggctt atgattcagt tcaccttgta gcaaacgcag caaaaggtgc
    10441 taaaaattca ggtgaaatca aggataacct tgctaaaaca aaagattttg aaggtgtaac
    10501 tggtcaaaca agcttcgatg cagaccacaa cacagtcaaa actgcttaca tgatgaccat
    10561 gaacaatggt aaagttgaag tagcagaagt tgtaaaacca taatagaaaa atgttgaaat
    10621 agggaatgag cctttgactc actccctgtt tcgatattta atactcttcg aaaatctctt
    10681 caaact
//
LOCUS       DAVBNZ010000068        10503 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000068 DAVBNZ010000000
VERSION     DAVBNZ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10503
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.068"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            164..376
                     /locus_tag="VQ860_001862"
                     /pseudo
     CDS             164..376
                     /locus_tag="VQ860_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            276..722
                     /locus_tag="VQ860_001863"
     CDS             276..722
                     /locus_tag="VQ860_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3120245.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(860..2164)
                     /gene="eno"
                     /locus_tag="VQ860_001864"
     CDS             complement(860..2164)
                     /gene="eno"
                     /locus_tag="VQ860_001864"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET3120246.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2328..2774
                     /locus_tag="VQ860_001865"
     CDS             2328..2774
                     /locus_tag="VQ860_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET3120247.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPLGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2771..3886)
                     /locus_tag="VQ860_001866"
     CDS             complement(2771..3886)
                     /locus_tag="VQ860_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET3120248.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPSGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4000..4224)
                     /locus_tag="VQ860_001867"
     CDS             complement(4000..4224)
                     /locus_tag="VQ860_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3120249.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            complement(4169..4540)
                     /locus_tag="VQ860_001868"
     CDS             complement(4169..4540)
                     /locus_tag="VQ860_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET3120250.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4599..6032)
                     /gene="glgA"
                     /locus_tag="VQ860_001869"
     CDS             complement(4599..6032)
                     /gene="glgA"
                     /locus_tag="VQ860_001869"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET3120251.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6029..7168)
                     /gene="glgD"
                     /locus_tag="VQ860_001870"
     CDS             complement(6029..7168)
                     /gene="glgD"
                     /locus_tag="VQ860_001870"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET3120252.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7158..8300)
                     /locus_tag="VQ860_001871"
     CDS             complement(7158..8300)
                     /locus_tag="VQ860_001871"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET3120253.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8290..10218)
                     /gene="glgB"
                     /locus_tag="VQ860_001872"
     CDS             complement(8290..10218)
                     /gene="glgB"
                     /locus_tag="VQ860_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET3120254.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGSLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3199 a         2300 c         1847 g         3157 t
ORIGIN      
        1 ttttttgaag cttggtttca gaaatttctc ttaccaacat taaccgcacc attggttatt
       61 atattaaaac gaagtaagaa taggacaaat cgatcaggac agtaaaatct aattctaaca
      121 atgttttaga agtagaggtg tactattcta gtttcaatct actatattaa tggacaatgc
      181 aagattccat agaatgggga agctagaact cttgtgtgaa gagtttgggc ataaactttt
      241 acctcttcct ccctactcgc ctgagtacaa tcttattgag aaaacatggg ctcatatcaa
      301 aaagcacctc aaaagggtat taccaagttg caataccttt tatgaggctc ttttgtctag
      361 ttcttgtttc aattgactat ataaattgtc taagcgaaac aaccgataag aattggcaca
      421 aaagcgaccg tatttttgtt accaatacag gaaaaccagt tcatagttct atcttgagca
      481 agtctctcca gcgagcaaac gaacgcctta aaaaaccaat tcccaaacat ctgtcccctc
      541 acatcttcag acacaccact attagcatct tatcagaaaa taaaattcct ttaaaaacaa
      601 tcacggacag ggttggtcat tccgactctg aagtcactac ttccatctac acccacgtca
      661 caaagaacat gaaagatgaa gcaatcaatg tactggataa agttatgaaa aagatttttt
      721 aaaaagtttt gtcccttttt tgtcctctaa atacaaaaat agcccttcgg ataaaatccg
      781 aggggctaga aacgttgtta aatcaacggc cgaacttttg aatttcatgg ttcgggataa
      841 aatagttcac tgaactattt tattttttaa ggttgtagaa tgatttcaat ccacgatatt
      901 cagctacttc accaagttgg tcttcgatac gaagcaattg gttgtattta gcgatgcggt
      961 ctgtacgtga aagtgaacca gtcttgattt gtcctgcgtt agttgcaact gcaatatcag
     1021 cgattgttga atcttcagtt tcacctgaac ggtgtgatac aacagcagtg taaccagctt
     1081 ctttagccat ttcgatagct tcaaaagttt cagtaagagt accgatttgg ttaactttga
     1141 taaggattga gttagcagca ccttcttgga taccacgtgc aaggtagtca gtgtttgtta
     1201 cgaagaagtc gtcaccaaca agttgtactt tcttaccaag acgttcagta agagctttcc
     1261 aaccatccca gtcgttttca tccataccat cttcaatagt gatgattggg tatttgttaa
     1321 ccaattcttc aaggtagtcg atttgttctg cagatgtacg aacagcagca ccttcacctt
     1381 caaatttagt gtagtcgtaa actttacgtt ctttatcgta gaattctgat gaagcacagt
     1441 caaatccgat aaatacgtct ttacctggta catatccagc agcttcaatc gcagcaagga
     1501 tagtttcaac accatcttca gttccttcga aacgaggagc gaatccacct tcgtcaccta
     1561 cggcagtttc caaaccacgt gatttaagga ttttcttaag agcgtggaag atttcagcac
     1621 cgtaacgaag ggcttcttta aatgttggcg caccaactgg caagatcatg aactcttgga
     1681 aagcgattgg agcgtcagag tgagaaccac cgttgatgat gttcatcatt ggagttggaa
     1741 gaactttagt gttgaatcca ccaaggtagc tgtaaagtgg gatttcaagg tagtcagcag
     1801 cagcacgagc tacagcgata gacacaccga ggattgcatt cgcacccaat ttacctttgt
     1861 taggagtacc gtcaagtgcg atcatagcac ggtcaatagc ttgttgatca cgtacatcgt
     1921 agccaatgat agcttcagca atgatgttgt ttacgttgtc aacagctttt tgtgtaccaa
     1981 gaccaccgta acgagatttg tcaccgtcgc gaagttcaac tgcttcgtgt tcaccagtag
     2041 aagctcctga tggaaccata ccacgtccga aagcacctga ttcagtgtaa acttctactt
     2101 caagtgttgg gttaccgcgt gagtctagga cttcgcgagc gtaaacatca gtaataattg
     2161 acatttttta ctctccttat gagttaaatt ttttacacct ctataatacc ttaaaacccc
     2221 tcctttttca agaaaaaacg ttatctttgt gcaacttttc cttaacttta taaagtaatc
     2281 gctttctttt gtctgtttta ttctaacttt tatgatatac tgttttcatg acagatttat
     2341 caaaacaatt acttgaaaaa gctcatggtg ggttaaaaat aaatccggat gagcaaagac
     2401 gctatcttgg tacttttgag gaaagagttc ttggatatgt agatattgac acagcaaata
     2461 gccctcagtt agaaaaaggc tttttattta ttttagaaaa ccttcaggaa aaagcagagc
     2521 cactatttgt gaagatttca ccaactatcg aatttgataa gcaagttttc tacttaaaag
     2581 aagcaaaaga aactgatagt caagccacca tagtatctga agagcatatt acttctcctt
     2641 tgggcctggt tattcatagc aatgcaccag ttcaagtaga agaaaaagac cttcgacttg
     2701 cttttccaaa actttgggaa gttaaaaagg aagaaccagc caaaacatcc ttatggaaga
     2761 aatggtttag ctaaatcttg cacatattta ataagtgccc aatattggca gccgtgcgct
     2821 ccagatagag actggcattt ttcaaactat cttctaaagg ttcacttttc tccaaaatag
     2881 aaaagacagc ttggatattt tcaaatggta ggggaggtaa atcttcagca agactaccgc
     2941 aaatagcaat aacaggaact ccaacagggg ttctttttgc aacacctata ggcgctttcc
     3001 cagcaaagct ttgactatca agtcttcctt ctccaacaac aaccaagtca gcatctgaaa
     3061 ctttcttatc aaagttgatt aagtccaagc aggtatcaat tccagacacg atacttgcct
     3121 gagcaaaggc acacaaacca ccagcaaggc ctccacctgc tcctgctcct ttaatttcta
     3181 atgttgcagg tgagaatttt tcataaaaat cttggatcgc ctgatctacg actgcaaaca
     3241 tagtcggatg tagacctttt tgattgccaa aagtgtaagt cgcaccttga tgaccacata
     3301 agggactcac gacatctgct agaatatgaa tttgaacacc ttcaggaatt ttatagcaat
     3361 tttctgttga aacagaagct aagtttaata aggattgatc ggaagcaggc aagacatttc
     3421 catccctatc ataaaattga taacctaaac cagcagcaat ccccagtcct ccatcattac
     3481 tggccgtgcc accaacaccg atataaatat ctttaatccc tttagaaatg agatggagaa
     3541 tcaactctcc aataccacaa gtttggattt gaagtggatt tcgtttctct agcggaattt
     3601 ttccaagacc aaccaagtca gctacttcaa atagtgccag ttcccctttt tgaaaatagc
     3661 gcatggcttc tttttgtcca gaagggtctg tcacttggat ccatttttct tttaggtcaa
     3721 gagaatgtcg gatagcatct acagtacctt ctcccccatc accaacaggg cagaggagac
     3781 attctacatc tgctatcgat tgttggaagc ctctttttat tgcttcagct acctgttgag
     3841 ctgtcaagct ttccttaaac gaatccggtg caattacaat cttcatattt tccctcattc
     3901 taaacagtca atcaaaggaa gaacttctaa aaaatccctc ttgtcaacat gatgtggtat
     3961 ttcttttttg agcatttctt tggaacaaaa ggcgattcct cactccgccg acttcaacat
     4021 taatagatta ttgaccccat caccgattgc caccgttctt tctttagaaa gttttagttt
     4081 ctttctccat ttttccagag tttctttttt gacctgggga cttataattt gtccaactaa
     4141 ttttcctgtt aaaagacctt ctttgacttc aagctggttg gcagtgaaat aggcaatacc
     4201 aagggatttt gctaatctct ccaactattg gtgtaaatcc accagacacc agaccaacta
     4261 ggatgccatt cttttggaga atagagatga actctgggac atttagcgat agatgaattg
     4321 agttgaagac gttatcaaag accaaaatag gaagaccttc caacaaggac actctttttc
     4381 ttaaactgct ttcaaagacc aactctcctc gcattgctcg acttgtaatc tgcgaaattt
     4441 ccgcctcatg acctgcctct ctccctaaaa gatcaatcac ttcttctagg attaaggttc
     4501 catctacatc caaaacacac aagcctttta cttgagacat cagttctcct ctctaaacag
     4561 cctaaaaatc gtatgaagtc atcatacgat tttatctatt aattaactaa actatggtac
     4621 aagtcaaggt atgacttgca ggctgtatcc catgagaagt cactctccat agcttgtttt
     4681 tgtaggtttc tccaaatgtc tggatggttt ctatacaagt ccaatgctgt ttggaaagtc
     4741 caatttaacc aataaggaga tagattgtca aagctaaagc cagtaccgct tccttcgatt
     4801 ggattgaaag cgcgaactgt atctcgcaag cctccaactt catggaccaa tggcaaggtt
     4861 ccataacgca tagccatcat ttgagacaag ccacacggtt caaaacgact tggcatgagg
     4921 aagaggtcac aagcagcgta gatttcctga gcaagtttga catcaaaagt gatatttgtt
     4981 gatagcttgt ctgggtaaat ctgagcaaac catgagaaag ctccttcaaa ggctggatcg
     5041 ccagttccca aaagaacaat ctgaacatct tcttgcaaga tatggtgaag actttcgacc
     5101 accacatcaa aacctttttg acgtgtcaaa cgagaaacaa ttcccaccag tggaacgtct
     5161 gctctaacag gcaagccaac tctttcttgc aattttgcct tatttttggc tttcccagac
     5221 aaatcttcct gattgaaatg atagtctaaa agagcatccg tctgaggatt ataaagatca
     5281 gcatcaatcc cattcacgat accagatact ttaccagact ccattttaag aatctgatcc
     5341 aaattacatc caaactgact agtcataatt tcatgagcat agctaggtga aacagttgaa
     5401 acacggttcg catagagaat acctgccttc atccagttca gacagttgtt ccatcgaagg
     5461 gtgccatcag cgtaacgttc aaagccaact ccaaacaaat cacccaacat tccttctgaa
     5521 aattgtcctt ggaattctaa attatgaatg gttaaaactg tttcaatgtc ctcataggct
     5581 tgaatccaac ggtatttttc cttcaacaag aaaggaatca tagctgtatg gtagtcatga
     5641 acatggagaa gatcaggaat aaagtcaatc ctttccatag cctcaatggc agccagttgg
     5701 aaaaaggcaa agcgttctcc gtcatcaaaa tcaccgtaaa catgaccacg gaagaaataa
     5761 tattgattgt caataaagta gaaggttaca ccatttaata ctgttttctt aattccacaa
     5821 tactgtctgc gccaaccaac gctcacctca aaatgaagca catcttcaat ctgacttcca
     5881 aatttagcct ctaccatatc atagtagggt aaaatcactg caacttcgtg cccagctttt
     5941 accagtgatt ttggaagagc gccaatgacg tctcccaaac cacctgtttt tgaaaagggt
     6001 gcaccctctg ctgctacaaa taaaattttc atgaatgaat atcctctgtt actttagcac
     6061 ctttcttaac cacaactgga tgttctgcag ttcctcgaat cacaacacca ggctcaactt
     6121 caaccccttt gtccaagata gcatattcga cctgagcccc ttctccaata acaacacgag
     6181 ggaagagcag gctatcttta accaagctat ccttatggac atgaatatta cgtgatagaa
     6241 cagaattagc tacttgacct tcaataatac taccagaggc aaactgagaa gtgcttacct
     6301 tagatgtatt agcatagtaa gttggctctt cgtttttgac ctttgtataa atcttttggt
     6361 ttggtgagaa aagagaatag aatttttgtg attcaagcat atcgatattc gcttgataat
     6421 aagatttaac agagtgaata ttggctagat agcccgtgta ctcgtaggcg aaagctccct
     6481 cttttacagc caaatcccgt aaaacatagc gcaatttctc tggatgttct tttttagctt
     6541 cttcttccaa gtgttcaatc aaccaaggtg tatcaacgac aaagatatct gtagacatat
     6601 tgaacgtttc agctgttgac ttgctatcaa agagtttatg agaaagaaca tggtctgttt
     6661 catctacatc caagattgca tttacttctg aaatatcttt cttagctagt tttttataaa
     6721 ctacagtgat aggctctttt gttgtactat gtaggtggaa aacttggttc aaatcaatgt
     6781 taataagaac atcgcagttg agggcaaccg tttggtttga gccagaacgt ttcaaataag
     6841 taagaagctg ttggtagtat tcttttccaa ctgtactact ttctacacgg gtattgtaaa
     6901 ttcctagata gtaatggcta agaagggttg ataagcccca ctcgcgtcct gaacgaatat
     6961 ggtcaaatac tgagctgata ttatcctgct ggaaaatacc aaagacacta cgaacacctg
     7021 cattagcaag gcttgaaagt gggaagtcaa tcaaacgata tttcccacca aatggcaaac
     7081 ttgctactgg acggtggtcc gtcaatgtcg acatattgtg aaaaccaact gtatttccta
     7141 aaatggcaga atatttatca atcttcatct gttgctaccc ccactacttc attatatcct
     7201 acaacttgta cttcatctgt tccatcaatt tcgacaccgt cagaaataat cgcaccttca
     7261 ccaataatgg cacgtttaat cttagctcct tgaccaatga tagctccact catgataact
     7321 gaatcaagga cttccgctcc ttcgcgaact tgcgcgcctg ttgaaaggat agaatgttta
     7381 acagttccat caacgaaaca tccgtctaca actaatgagt cttccacatg agcatttgcc
     7441 ccgaggaagt ttggtggtga aatcaagttt cttgagtaaa tcttccattg acggttacga
     7501 ctatccaagg cattttctgg agaaatatac tccatgttcg cttcccaaag tgactcaata
     7561 gtaccaacat ctttccaata accactaaat tcataagcat aaacactttc acctgactca
     7621 aggtaatttg gaatgacatt tttaccaaag tctgacatgc caaccttgct cttttcagca
     7681 gcgactaaca tattacgaag gcgttgccaa tcaaaaatgt agattcccat agaagctttt
     7741 gtagatttag gttgagctgg tttttcttca aattcaacaa tacgattgtt agcatctgtg
     7801 ttcatgatac caaaacggct tgcttcttta agagggacgt ctaaaactgc tactgtcaag
     7861 ctggcattat tatccttatg agactggagc atatcatcat agtccatttt gtagatgtgg
     7921 tccccagaca aaatcaagac atactcagga ttgacactgt cgatatagtc gatattttgg
     7981 taaatagcgt gactagtccc ctcaaaccaa cgatttcctt cacttgcaga ataaggttga
     8041 agaatagaga cacctgaatt aataccgtct agtccccagc ttgaaccatt cccaatatgg
     8101 ttgttgagag caagtggttg atactgtgta acgaccccaa cattatgaat ccctgagttg
     8161 gcacagtttg atagggcaaa gtcaatgata cggtagcgcc caccaaattg cacagctggt
     8221 tttgcgatgc tttgagtgag tttaccgaga cgagttcctt gcccaccagc aagaatcaaa
     8281 gctaacattt catttttcat tttctactcc tttttggttt ttatttgtga cggttttagt
     8341 agatttcaag cgacgtttga ttttccatac acttgctccc atagccggta gagtaaaggt
     8401 taaggtctgc tcataatctt tccatagtcc ttcttgcgtt tgaacagttt gattatgttc
     8461 tttccaaacg cctccccact cttccaactc agtattccat acttcttcgt aaattcctgc
     8521 aacgggtagt ccgattgtaa aatctttccg ctcaacaggt accatattaa agatacagac
     8581 taacatttct ccctttttac ccttacgaat aaaggaaaga acactctggt ctcgattatc
     8641 cgcatcaatg atttcaatac catcatagct ggtatcaatt tcccacagac agcgatgatc
     8701 tttgtaaaac tggtttagct gagaagcgaa atacttcatc ttagcattca ttgggtcttc
     8761 taggttagac cattccaact gttcttcaga tttccattct aggaattgac cgtattcgct
     8821 acccatgaag agcaatttct taccagggtg acaaatttgg tacgtataga gattgcgcaa
     8881 gcctgcgaat tgattgtaac gatctcccca catcttatgc atcatactct tcttgccatg
     8941 aaccacttca tcgtgcgaga atggcaagag ataattctcc ttgaaaacat acataaagct
     9001 gaaagtcacc aggttaaagt catatttacg ataaatcgga tcttcttcgt agaaacggag
     9061 gatatcattc atccagccca tgttccattt gtagtcaaat cctagactac caatctcttt
     9121 cattcccgta atcttggtcg cagacgaact ttcttctgca atcatcatca catctggata
     9181 ttctaactta ataacttcat tcaagcgttg aagaaaataa taaccttcat agttgagatt
     9241 tccgccatct ttattaggtg tccatggagc attatcatag tccaaataga gcatgttgct
     9301 aacagcatcc acacgaatac catccaaatg atagacatca atccaatgct taatgcaaga
     9361 aattaagaag gactggactt cattttttcc aaggtcaaaa ttaagggcac cccaaccatg
     9421 gttatgagcc ttattatggt cttggtattc aaaagtcggt gtcccatcat aataggctaa
     9481 ggcatcatcg ttgatggtaa agtgacctgg tacccagtcc acaataaccc caatattatg
     9541 ggtatgacac tcctcgacaa aatcttgaaa ctcctctggt ctgccataag catgctctaa
     9601 agcgaagtaa cccataagct gataccccca actcaagccc aaaggatggg acatcaaggg
     9661 cataaactca atatgagtat agttcatttc aacgagataa ggaatgagtt catccttgag
     9721 ctgggcaaaa ctataaggac tgccatcaga atttcttttc catgatccag cgtgaacttc
     9781 ataaatattg acaggacgct cttcaaagcc ccaacgtttt cttcgtgcca gccaaagtcc
     9841 atccttccat ttcttctcag gaagctctgt taagattgcc cctgttcctg gacgagcctc
     9901 atacctgaca gcaaaagggt caatcttcat cagttgatga ccattttgac gtgtgacatg
     9961 atatttgtaa atatgccctt cttgagccat attggtaaag acttcccaga ccccaaaatc
    10021 atttcttacc attggaatct gattttcaat ccagttggta aaatcaccaa ccaagtgaac
    10081 agcctgagca ttaggtgccc aaacacggaa ggtatagcca tgctctccat ttagttcttc
    10141 cctatgtgct cctagataat gttggagata aaaattttca cccgtcataa aggtttttaa
    10201 tgcttctcta ttatccatat actccccttc tcctgtaagc gttttctatg tttttattat
    10261 actacctttt tagagaagat tcaagtaaat tactatactt ctttaattat tttgaaaatc
    10321 tacaacaagt tcacttactc gttcaattgt aaatcaatat tttttcaaaa aattgcgaaa
    10381 acgcctttct ttttctacta tagtgaaatg aaataaaaca tgcgcaagtc gattaaggaa
    10441 tttaatctaa tttctaacaa tgtcttagaa atcaaagtgt actattttaa cttcaatgta
    10501 cta
//
LOCUS       DAVBNZ010000069        10492 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000069 DAVBNZ010000000
VERSION     DAVBNZ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.069"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(26..628)
                     /locus_tag="VQ860_001873"
                     /pseudo
     CDS             complement(26..628)
                     /locus_tag="VQ860_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(1214..1990)
                     /locus_tag="VQ860_001874"
     CDS             complement(1214..1990)
                     /locus_tag="VQ860_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET3120255.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            2112..2858
                     /locus_tag="VQ860_001875"
     CDS             2112..2858
                     /locus_tag="VQ860_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3120256.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            2871..3851
                     /locus_tag="VQ860_001876"
     CDS             2871..3851
                     /locus_tag="VQ860_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET3120257.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGI
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            4046..4366
                     /locus_tag="VQ860_001877"
     CDS             4046..4366
                     /locus_tag="VQ860_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3120258.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            4412..4720
                     /locus_tag="VQ860_001878"
     CDS             4412..4720
                     /locus_tag="VQ860_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3120259.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            4737..6035
                     /locus_tag="VQ860_001879"
     CDS             4737..6035
                     /locus_tag="VQ860_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3120260.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            6186..8624
                     /locus_tag="VQ860_001880"
     CDS             6186..8624
                     /locus_tag="VQ860_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET3120261.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            8643..9311
                     /locus_tag="VQ860_001881"
     CDS             8643..9311
                     /locus_tag="VQ860_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET3120262.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            9329..10417
                     /locus_tag="VQ860_001882"
     CDS             9329..10417
                     /locus_tag="VQ860_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET3120263.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT         3438 a         1487 c         2086 g         3481 t
ORIGIN      
        1 aatttgtcct gttcttattt cattttacta taccatcaat aagtgtgaaa agatctttta
       61 cataagacca agccttatta tctttgtaac caccttgagc ttgtagcata tttgttaatt
      121 gagcaaaggc gctagaagag tttgctgggt cagcagttgc gatttttcct tttagttcag
      181 gtttgagaag gtcgctatat ccttcgatgt tcatgccttt agttaaatca gggtggacga
      241 ttaaaacact accatctagt gtataaggag tagagaagcc agttgtgttt tgatattctt
      301 tgataacatt atcattttct tttgaaatat agttttcaaa gagttctccg tgggtagcat
      361 attgtgtata agaaccacca aagataacat cagctacagg aacttctttt tctgactcta
      421 gttttttgaa aagttctcca gtaccagctt gaatcagttc tattttgata ccatattttt
      481 cttcaaaggc aggaatagtt gctccaatta agccttctga gtttggtgaa taaacgacta
      541 gcgaaccacc gtctccttta tcagatgaac tgtcatcggc agattcatta gaagaacaag
      601 cagcataata catccatttc tttttcatga tggatacctc cgttgtgtta tttaagttta
      661 ttttaaaaca atgtaagcgt ttttaaaacc tacaattcta ttctatagtg tattgaatct
      721 ataacagtac accttgactg ctaaaatatt tctataaatt aatttgactt tcctgataga
      781 gatgttcaca tcttatttca attcactata ttagagtaaa attctctaca aaaaaaagaa
      841 tagcctattt tactattttt ccgagtgatt tcaattcctt tggggaaata tggagatact
      901 ttttaaatcc tgacaaatgg ttgtttcttt ttctaaatcg gtgatactgt atcggagaat
      961 gcgcgtgagg tcacaaaggc tgcgatagag cttctatgga gaatttcttt ttggagagat
     1021 tttttaaagg aatgagacat ccgctacctc cttggaaggt tttttgtgat aagtatagca
     1081 gtttaaaaat tctagagcaa ggtaaaatag aaaaggtttg gctaaaattt tttagctaaa
     1141 ccttttgaaa agttaagtat gtattataga tgcttgttat ctgcaaatat ctagagcatt
     1201 tcaaggaaat aaactagaaa taacaattaa tatggtggtt cagaaatacc ttttgataat
     1261 caataagatc ttcaggatga agtgcgttga ctccatccat ttcatatttc cgatttaata
     1321 aacgatattt gttttcacca aattgatgaa aagggagtag ttgaacttgg tcgatattta
     1381 atgagttaaa tagagtagcg aatttttctg catcctctaa actattgtta aaattaggaa
     1441 taactgggat tcttaaaacg atagttttat tttgagaaaa agcataatga atgtttttaa
     1501 taatcatttg attaaaaacc ccagtcactt ttttatgttt tatagaatta taatgtttta
     1561 ggtctgtgta gataaaatcc acatattgaa ttaaatcgat aaatttttca tgatcaacaa
     1621 aggcagtagt ttcaatggca gtgtgtatgt gatgttcttt agctgatttt aagatggctt
     1681 tagcaaattc aaactgagca aatatttcac ctcctgataa agttaaacct ccaccggatt
     1741 cttcgtaaaa ttctttgtct tttaatacct ctgtaataat ttcttctaca gtcttttctt
     1801 caccgactaa ggtgaatttc tctcgttgag catctttcat tttttcaggt ttcattcttt
     1861 gagattcagg attagaacac catggacagc gcagaggaca tccttttaaa aaaacagttg
     1921 tacgaatacc cgggccgtca tgaattgaaa agtgttgaat attaaaaata attcctttag
     1981 atatttccat aagagttcct cctcttcata agtctatcct atcacaaaaa cgaaagaaaa
     2041 acaattacga acgaaaggtt aatttgttgt tttttgcttt ttattttggt agaataaaac
     2101 ggaggtgtaa aatgaaaaga ttggaacaaa ttattaaatt agtatcagaa tatgaaaaga
     2161 tcgacgttaa tacattatcg gaaaaattaa atgtatcgaa agtaacgatt agaaaagatt
     2221 tagataaatt agagtcaaaa ggtttattac acagagagca tggatatgct gtattaaata
     2281 gtggagatga cttaaatgta cgtttgtcaa ttaattatga aattaagaga aaaattgttc
     2341 aggaagcagt aaaattggtg tcagataatg aaacaataat gatagaatct ggatcgacct
     2401 gtgctttact tgctgaggaa atttgcaagc aaaaaagaaa tgttacgatt gtaacaaatt
     2461 cattttttat agcaaatttt gtgagagctt atgattcatg tcgtattatt gttcttggtg
     2521 gagagtttca gaaggattca caggttactg tgggaccttt attaaaagaa atgatacaga
     2581 cttttcatgt gcgtcaagct tttgttggga cagatggcta cgataaagag atgggcttta
     2641 caggaaaaga tttaatgcgc agtgaggtag ttcaatatat ttcagcagcg tcggataaag
     2701 tcattgtact aactgactca agtaaatttg ataaaagggg tacagtaaga agatttgctt
     2761 taagtcaagt ctatgaagta ataacagacg aaaaactttc taaacaaaat atagctacat
     2821 tagaaaatgc tgggataatg gttaaggtag tttcgtaaga ggttaagtgt atgaatcaag
     2881 ataggaataa actgctctct aaaattgctt atctgtatta tattgaaaac ttaaatcagt
     2941 cacaaatagc agcaaaatta ggaatttata gaacctctat tagtagaatg ttaacagaag
     3001 caaggaatgc aggaattgtt aaaattgaaa tagagaattt tgataccaat atgtttaagt
     3061 tggaaaatta tgtaaaagaa aaatatggtc tggaaagttt agaaattatt ccaaatgaat
     3121 ttgatgataa tccaacaatt ttatctgaaa gaatttctca agttgcagca ggtatcctta
     3181 ggaatctaat tgatgataat atgaaaattg gcttttcttg ggggaaaagt ttaagtaatt
     3241 tagtagattt aattcacagt aaaagtgtcc gaaatgttca cttctatcct ctagcaggtg
     3301 gtcctagtca catacacgct aaataccatg tgaatacact gatttatgaa atgtctagaa
     3361 aatttcatgg agagtgtaca tttatgaatg caacgattgt gcaagaaaat aaattgttag
     3421 cagatggtat tttgcaatca agatattttg aaaatttgaa aaatagttgg aaagatttag
     3481 atatagctgt agtcggaatt ggtgatttta gcaataaagg aaagcatcaa tggttagaca
     3541 tgcttacaga ggatgacttt aaagaattga ccaaagttaa aactgtagga gaaatttgtt
     3601 gtcgattttt tgattcaaaa ggtaaagaag tctatgaaaa cttacaggaa agaacgatag
     3661 caatctcttt ggaagattta aaaaatattc ctcaaagttt agctgttgct tacggtgata
     3721 cgaaagtatc ttcgattctt tctgtcttgc gtgctaattt agtaaatcat ttgattacag
     3781 acaaaaatac aattttaaaa gttttggaag aagatgggga tttgactttt agagagattc
     3841 taggtgagtg aaaatgatag actgattcag tttatcgttt ttctttttag ttgattgcac
     3901 atttgtgctt atataaacaa aaatagttta tctgttgttt ttggattgac aactttatta
     3961 tgtagttgta ttctatagtt acaaaagaaa attttaaaat ttcaaatgaa aaaagctttt
     4021 tacatagtga aatgaggagg aatttatgga aattattgtt ccagatcaaa ttatcatggg
     4081 tttaatttta tatgctggcg atgcgaaaca acatatttat aaagcattag attacataaa
     4141 gaacggtaca tgtgaacgat gtgaagaaga aatccagtta gctgatgccg ccttattaga
     4201 agctcataat ctacaaacaa aattcttggc acaggaagcg tctggtacaa agacagaaat
     4261 tacagctctc tttgttcatt cacaagatca tctcatgact agtatgacgg agattaattt
     4321 aatcaaagaa attattagtt tgagaaaaga acttcataaa aaataatact agagtattat
     4381 cattgttatt aacatagagg aggaaaacat aatggtgaag attggtttgt tttgtgcagc
     4441 aggtttttct actggtatgc ttgtaaataa tatgaaaatt gcagcgcaag ctagtggagt
     4501 tgaggcagaa atagaggcgt tttctcagtc taaattagcg gattatgcgc caaatataga
     4561 tgttgcacta ttgggtccac aagttgctta tacattagat aaatcaaaag aaatttgtga
     4621 taagtgtgat gttccgatag ctgttattcc gatgatggac tatggtatgt tagatgggaa
     4681 aaaagtatta gatttggccc tatctttgat tagtgggtaa gaaaaggaga tttattatgt
     4741 caaagatgga tgttcagaaa atcattgcac cgatgatgaa gtttgtgaat atgcgtggca
     4801 ttatagctct aaaagatggg atgttagcaa ttttgccatt gacagtagtt ggtagtttgt
     4861 tcttgattat gggacaattg ccgttcgaag gattaaataa gagcattgct agtgtttttg
     4921 gagctaattg gacagagccg tttatgcaag tatattcagg aacttttgct attatgggtc
     4981 taatttcttg tttttcaatt gcctattctt atgctaagaa tagcggagta gaggctttac
     5041 cagctggagt tctatctgta tctgcattct ttattttgct aagatcatct tatatcccta
     5101 aacaaggtga ggcgattggg gacgctatta gtaaagtttg gtttggaggc caaggaatta
     5161 tcggtgctat cattataggt ttggtagtag gaagtattta taccttcttt ataaagagaa
     5221 aaattgttat taagatgcca gaacaagttc cacaagctat tgccaaacag tttgaagcaa
     5281 tgattccagc atttgtaatt ttcttatctt ctatgattgt atatatttta gcgaagtcat
     5341 tgactaatgg cggaacattc atagaaatga tttattctgc tattcaagtt ccgttgcaag
     5401 gtttaactgg atctttgtat ggtgctattg gaattgcatt ctttatatca tttttgtggt
     5461 ggtttggtgt tcatgggcaa tcggtagtaa atggagtagt gacagctctg cttttatcta
     5521 atcttgacgc taataaagct atgttagcct ctgctaatct atcattagaa aatggtgcac
     5581 atattgttac tcaacaattt ttagattcat ttttaattct atcaggttca gggattacgt
     5641 ttggtcttgt agttgccatg ctttttgcag caaaatcaaa acaataccaa gccttaggaa
     5701 aagttgcagc ttttccagca atatttaacg taaatgagcc agttgtattt ggatttccga
     5761 ttgtcatgaa tccagttatg tttgtacctt tcattcttgt tcctgtactt gcagctgtga
     5821 tagtatatgg agctattgca acaggtttca tgcagccatt ctcaggggta acattgcctt
     5881 ggagtacacc agctattcta tcaggatttt tggtgggtgg atggcaaggt gttgtgactc
     5941 agttattagt attggtgata tctacagtgg tttactttcc attctttaag atacaagatc
     6001 gtttagctta ccaaaatgaa atcaaacaat cttagaggta tttgtgtgtt actgttaaac
     6061 tcacacattt gtgctaaaaa ttagagagtt aaaatttttc tagttaaaag cttgaaaatt
     6121 tctataaaaa tcggtattat attttcgaaa gaaataaaaa tattttcgaa agaaaggtgc
     6181 ttacgatggt aaatacagaa gtagcaagaa caacaatcaa gacagaatat tttggcagcc
     6241 ttactgaaag gatgaacaaa tatcgagaag atgttttaaa taaaaaacct tatattgatg
     6301 ctgagagagc agttctagca acacgcgcct atgaacgata caaggaacaa cctaatgtcc
     6361 taaaacgtgc atatatgctg aaagaaattt tggaaaatat gtctatctat attgaagaag
     6421 aatctatgat tgcgggaaat caagcttctt ccaataaaga tgctcctatt tttccggaat
     6481 atacgctaga atttgttctc aatgagttgg atctttttga aaagcgtgat ggagatgttt
     6541 tctatattac agaagaaaca aaagaacaac ttagaagtat tgctccgttt tgggaaaata
     6601 ataatttacg tgctagagct ggtgccttat tacctgaaga agtgtcagtt tatatggaaa
     6661 caggattctt cggtatggaa ggtaagatga attctggaga tgctcactta gcagttaact
     6721 atcagaaact tttgcaattt ggtttaagag gttttgaaga gcgggctcgt aaagcaaaag
     6781 tagctctaga tttaacagat ccagcaagta ttgataaata tcatttttac gactctatat
     6841 ttattgtaat cgatgctatt aaagtatatg caaagcgctt tgttgctctt gctaaaagtt
     6901 tagccgaaaa tgcaaatcct aaacgtaaga aagaattact tgagattgca gatatttgct
     6961 ctagagtccc atatgaaccg gcaactactt ttgcagaagc tattcaatca gtttggttta
     7021 ttcaatgtat tttacaaatt gaatctaatg gccactctct ttcatatggc cgttttgatc
     7081 aatatatgta tccatatatg aaggctgatt tagaaagtgg taaagaaaca gaagatagca
     7141 ttgttgaacg tctgacaaat ctttggatta agacaattac aattaataag gttcgcagtc
     7201 aatcacatac attttcttca gcaggaagtc ctttatatca aaatgttaca attggtggac
     7261 agactcgaga taagaaggat gctgttaacc cattatctta tttggtatta aaatcagttg
     7321 cacaaaccca tctaccgcaa cctaatctaa ctgtacgtta ccatgcaggt ttagatgctc
     7381 gtttcatgaa tgagtgtatt gaagtgatga aacttggttt tggtatgcct gcatttaata
     7441 atgatgagat tattattcct tcttttattg caaaaggagt attggaagat gatgcttatg
     7501 attacagtgc cattggatgt gttgaaacgg cagttccagg gaaatggggc tatcgttgca
     7561 caggtatgag ttatatgaac ttccctaagg ttctacttat cacgatgaat gatggaattg
     7621 atccggcttc gggtaaacgg tttgcaccaa gctttggtca ttttaaggat atgaagaact
     7681 tttctgaatt agaaaatgct tgggataaaa cactaagata tttgacacga atgagtgtta
     7741 ttgttgaaaa ttctattgat ttatcattgg aacgagaagt tcctgatatt ctatgttcag
     7801 cattgactga tgattgtatt ggtcgtggaa aacaccttaa agaaggtgga gcagtatatg
     7861 attatatatc aggattgcaa gttggaattg caaatttgtc ggattcatta gctgcaatta
     7921 aaaaattggt gtttgaggaa gaacgtataa gcccaagtca gctttggcat gcactggaaa
     7981 cagattatgc cggagaagaa ggtaaggtca ttcaagaaat gttgattcat gatgcaccta
     8041 agtatggtaa tgatgatgat tatgctgaca aattggttac tgctgcttat gacatttatg
     8101 ttgatgaaat tgctaaatat cctaatacac gttatggaag agggcctatt ggaggaattc
     8161 gttattcagg aacatcttct atatcagcca acgtagggca gggacgtgga acattagcaa
     8221 ctccagatgg acgcaacgcg ggtacaccgt tagcagaggg ttgttcacca tcacataata
     8281 tggatcaaca cggccctaca tctgttttaa aatctgtttc aaaattacca acagatgaaa
     8341 tcgtaggtgg ggttctctta aatcagaaag taaatcctca aacgttagcc aaagaagaag
     8401 ataaattaaa actaattgct ttgttacgaa cattctttaa tcgtttacat gggtaccata
     8461 ttcaatacaa tgttgtttcc agagagacgt tgattgacgc tcagaaacat cctgaaaaac
     8521 acagagactt aattgttcgt gttgcaggat actctgcatt cttcaatgtt ctttctaagg
     8581 caacccaaga tgacattata ggacgtactg agcatacttt gtaaaataaa gaggttcttt
     8641 ttatggaatt tatgcttgac acattaaatt tagatgagat taaaaagtgg tctgaaattt
     8701 tgccgctagc tggggtaact tcaaatccca ctattgcaaa aagagagggt tctattaatt
     8761 tttttgaacg aatcaaagat gtaagagaat tgattggctc cacaccctct attcatgttc
     8821 aggtgatttc tcaagatttt gaaggcatct taaaggatgc tcatgaaatt cgaagacaag
     8881 caggagatga tatatttatc aaagtacctg ttactccagc tggattacgt gcaataaagg
     8941 tgctaaaaaa agagggctac catatcactg caacagctat ttatacagtt attcagggat
     9001 tattagctat cgaagtagga gcggattacc tagctccata ttataataga atggaaaatc
     9061 tgaacattga ttcaaattct gtcattcgtc aattagctct tgctattgat agacagaact
     9121 ctcctagtaa gattttagct gcatccttta aaaatgtagc acaagtaaat aatgctttag
     9181 ctgcaggtgc gcatgctgtt acagcaggag cagatgtttt tgaatcagct ttcgccatgc
     9241 catctatcca aaaggcggtt gatgattttt ctgacgattg gtttgttact caaaatagtc
     9301 gttccattta gatagagagg aaatacatat gagaattttt gctagtcctt ctagatatat
     9361 tcagggggaa aatgccttgt ttgaaaatgc caaatcaatt ttggatttgg gaaattaccc
     9421 gattctatta tgcgatcagt tggtttatga tattgttgga aaacgatttg aagattatct
     9481 acataggtat ggtttccata ttgttctggc gctatttaat ggtgaagctt ctgacaatga
     9541 aatcaatcga gttgttgcct tggctgagaa agaaaattgt gatagtatta tcggtcttgg
     9601 tgggggaaag acgattgata gcgcaaaagc tattgcagat ttgattgaaa agcctgttat
     9661 tattgctcca acaattgcat cgaccgacgc acctgtatct gctttatctg ttatttatac
     9721 agatgaaggt gcatttgatc attatctatt ttattctaaa aatccagatt tagttttggt
     9781 tgatacaaaa gttatttcac aagcccctaa gcgtttatta gcgtctggta ttgcagatgg
     9841 tttagcaact tgggttgagg cgcgtgcggt tatgcaggca aatggaaaaa ctatgttggg
     9901 acaacagcaa acattggctg gagttgcaat tgcgaagaaa tgtgaagaaa cgctgtttgc
     9961 agatggttta caggctatgg cagcttgtga agctaaagtg gtgacaccag cattagaaaa
    10021 tattgttgaa gctaatactt tattgagtgg tctaggtttt gaaagtggag gattagctgc
    10081 ggcgcatgca attcataatg gttttactgc attgacaggt gacattcatc atttaacaca
    10141 tggtgaaaaa gtagcttatg gaactttagt acaactatta ttggaaaata gacctaaaga
    10201 agaacttgat aagtatattg agttttacaa aaaaattggt atgccaacaa ctctaaaaga
    10261 aatgcatttg gatcaagttg gatatgatga tttaataaaa gttggtaaac aagcaactat
    10321 ggagggtgag acaattcatc agatgccgtt taagatttcg ccctcagatg ttgctcaagc
    10381 tattatcgct gtagatgcct atgtaaattc aaaataaaca ataaggacta ctgttttcca
    10441 aatggtagtc ttttattgat ccctgtattg aattctatag cagattgaaa ta
//
LOCUS       DAVBNZ010000070        10470 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000070 DAVBNZ010000000
VERSION     DAVBNZ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10470
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.070"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(100..903)
                     /locus_tag="VQ860_001883"
     CDS             complement(100..903)
                     /locus_tag="VQ860_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET3120264.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1178..1933)
                     /locus_tag="VQ860_001884"
     CDS             complement(1178..1933)
                     /locus_tag="VQ860_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET3120265.1"
                     /translation="MSKHPHYELLNLIGYGLAKFAKLFIKEFQYSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNSRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYVEIVKM
                     LLASEGKQTGITIIEKPIIRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDACLY
                     GDGYDFQVDIQEHSYLAEVKGIRKPKGRVRLTAYEFEKAKEFQSDFILSLVTNLDDIP
                     KLVLVDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2003..4654)
                     /locus_tag="VQ860_001885"
     CDS             complement(2003..4654)
                     /locus_tag="VQ860_001885"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET3120266.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(4647..5225)
                     /locus_tag="VQ860_001886"
     CDS             complement(4647..5225)
                     /locus_tag="VQ860_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3120267.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5225..5785)
                     /locus_tag="VQ860_001887"
     CDS             complement(5225..5785)
                     /locus_tag="VQ860_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3120268.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWGVI"
     gene            complement(5772..6221)
                     /locus_tag="VQ860_001888"
     CDS             complement(5772..6221)
                     /locus_tag="VQ860_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HET3120269.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(6634..7029)
                     /locus_tag="VQ860_001889"
     CDS             complement(6634..7029)
                     /locus_tag="VQ860_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET3120270.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQTAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASHFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(7125..7379)
                     /locus_tag="VQ860_001890"
     CDS             complement(7125..7379)
                     /locus_tag="VQ860_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET3120271.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7389..8723)
                     /locus_tag="VQ860_001891"
     CDS             complement(7389..8723)
                     /locus_tag="VQ860_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET3120272.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8723..8956)
                     /locus_tag="VQ860_001892"
     CDS             complement(8723..8956)
                     /locus_tag="VQ860_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET3120273.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(9269..9409)
                     /locus_tag="VQ860_001893"
     CDS             complement(9269..9409)
                     /locus_tag="VQ860_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120274.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9406..9588)
                     /locus_tag="VQ860_001894"
     CDS             complement(9406..9588)
                     /locus_tag="VQ860_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120275.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(9590..10369)
                     /locus_tag="VQ860_001895"
     CDS             complement(9590..10369)
                     /locus_tag="VQ860_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120276.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT         3041 a         2341 c         1944 g         3144 t
ORIGIN      
        1 tttggggtca gtacatttta acacttgata ctatgcgttt tattgtggga atgtttactt
       61 cattttttcc taaaattcaa tgtttactca gtatttggat tatgaaaaat cgaggtctaa
      121 atctagatac attttttctg aagacaaatc attttgacca ccgagcaaga gattttcaaa
      181 aaaagctgtt aaaaactcag gacgtcgctg taaaatcttt gcattatcta ataccaaggc
      241 atcacgaaaa tacttggaat gttgctgaaa tggtatatta tcaatatcaa aaccaaactc
      301 acgaagatac tgaatcaaaa agaccgttac tgtccgagtg tttccttcgc gaaatggatg
      361 aatctgccag attcctgaaa taaaatgctg gatttgttta accacatccg cctgagttag
      421 tgtcgcatat gcaacttgtt tttcctgatt aaaatcataa tctaaggtca tttgaatcat
      481 ggagtaatca gagtacacaa cactttcacc attcaaaaca ggttcattct ttgtgatatt
      541 ggtctgacga aattgcccca ccggaataga gggttcaaat atatcttgaa acaactcctt
      601 atgaatagca agtaaggtcg caggactaaa gctaaagcct cttcgagaca atagttctac
      661 aatacgtaga gaaaccaagt ctgcctcttc cgtacttgca tcaatagtat ggtgataagc
      721 cgttgcatcc tcataaacct gctcataagt cagttctccc cgggactgtt tctcagccaa
      781 agattccata tacgctgatg gcactagatt gtcaactttc tgcagaccaa aacctatccg
      841 ccataaatca cgcttcgctt cataagacaa gtttggattg tcaatgttgt aagttgattg
      901 catagaaata tcctttcaat tgtttttctt cattaccagt aaatcacgaa attggttgga
      961 aactggctta aactataaaa agtcctcaca ataggttcta tgatatatat atacttcatg
     1021 taaataataa aagagttata atcagcacta ctgataaatt caataccgat ttcgccatct
     1081 taaaacttag tcaaacgaat accgttgatt tccagttcat taagtcgttg acctgtcaag
     1141 acttctcgtt ccttcaactg gaaaagttaa gggggaacta atacaaatcc tctacgcttc
     1201 tatattcaat gatttcattt tttataatat tctttttaaa ctcaaaatgt tttagaggat
     1261 tatcaactaa tactaacttt ggaatatcat ctaggttggt gaccagagat aaaataaaat
     1321 ctgattgaaa ctctttagct ttctcaaatt cgtaggcagt taaacggaca cgacccttag
     1381 gttttcgaat ccctttaact tcggcaaggt aggaatgttc ttgaatatct acttggaaat
     1441 catatccatc accataaaga catgcatcgg ttaactgtcc accttgaaat ttttcttctt
     1501 tatcaaaatg aaggataaaa taattctctg cctccatccc cgtttcctgt agacgtttga
     1561 atttagttcg aataattggt ttttcaatta tagtaatgcc tgtttgcttt ccttcactag
     1621 caagtaacat tttaacaatt tcaacataac tatgaacatc ttcatttcca aacatcatat
     1681 caattaaatc tttacgaaaa cggtaaactt cagctttctg ccaccaacct tttcgactat
     1741 tgtcaaaata aggatcaaat aaatccattc tattttttac aactccagtt gtttcagcaa
     1801 ttcccaaaga aaccacatag cgataaaact ccgacttact agaatattga aattctttta
     1861 taaaaagctt ggcaaacttg gcaagaccgt agccaattaa atttaacaat tcataatgcg
     1921 ggtgtttaga catcactttc tccatcaata gatagtaatt tcattatccc aaaaaacacg
     1981 gcattacacc atgtttctgt gtttatttca ccaacttctt catctcatca atacgtgcta
     2041 cggtcgcatc atacttggct tggtagtcag cttgtttgtc gcgttctttt tggacgactt
     2101 ctggtttggc gttggctacg aagcgttcgt tagagagctt cttaccgacc atgtccagtt
     2161 ctttttgcca tttagcaagt tccttgtcaa gacgagccag ttcttcttcg acattgagga
     2221 ggtcagccaa tggcaggtag atttctgctc ctgtaatgac gcttgacata gccagttcag
     2281 gtgcagggat ggttgatgcg atttccaagt gttctggatt tgtaaagcgt ttgatatagt
     2341 tgacattgct gttaaagaag gcttccaagt cgctatcgct tgtcttaaca aggatggtga
     2401 taggcttgct tggtgctacg tttacttccg cacgcgcatt acgaacggca cggatcaagt
     2461 ctttgagact ttctacacca gtatgagccg caaggtcttc aaaggctaga ttaacagttg
     2521 ggtatgcagc tgtcacgata gaaccttctg agatttgtcc aaagatttcc tctgtcacga
     2581 atggcatgat tgggtgaagg agacgaagga tcttgtccag agtgtaaagg agaacagatc
     2641 gagtaatgac cttatcgtct tcattgtcgc tgtaaaggac ttccttggtc aattcaacat
     2701 accagttggc aaattcttcc caaatgaagt tgtaaaggat atgaccagcc acaccaaact
     2761 cgaacttatc aaagttttca gtaacttttg caatggtttc gttgagattg tggagaatcc
     2821 agcggtccgt cacattacca gcctcacctg ttgcaacttt tgtgacattg tcatgcgcca
     2881 catccagcgt caaaccttca ttgttcatga ggatatagcg agaaatgttc caaattttgt
     2941 taataaagtt ccatgaagca tccattttct cgtaagagaa acgaacgtct tgaccaggag
     3001 ctgagccgtt tgacaagaac caacgaagac tatctgtacc atatttatca ataacatcca
     3061 ttgggtcaat gccatttcca agagatttag acatcttacg tccttcttca tcacgaatta
     3121 gaccatggat aaggacgttt tggaatggtt gacggcctgt gaattccaat gactggaaga
     3181 tcatacgaga cacccagaag aagatgatgt cgtaacctgt taccaaggtt gaagttggga
     3241 aataacgttt aaagtcttct gagtcaactt caggccagcc catggttgaa aatggccaga
     3301 gggcagaact gaaccaagta tccaagacgt cttcgtcctg agtccatccg tcaccttctg
     3361 gagcttcttc gccgacatac atttcaccat cagcattgta ccaggcaggg atttggtgac
     3421 cccaccaaag ctgacgagag ataacccagt cgtggacatt ttccatccat tgaaggaagg
     3481 tatcgttgaa acgaggtggg tagaattcga ccttgtcctc tgtgtcttgg ttggcaatgg
     3541 cgttcttagc caattggtcc atcttgacga accattgagt agacaagcgt ggctcaacta
     3601 cgacacctgt ccgttctgag tgaccgactg aatggacacg tttttcgatt ttgacaaggg
     3661 caccgatttc ttccaactta gcaacgactg ccttacgagc ttcaaaacga tccatgcctg
     3721 aaaattcaaa ggcaagctca ttcatagttc cgtcgtcgtt catgacgttg acttgtggca
     3781 agttatgacg ttggccaacc aagaagtcat ttggatcgtg ggcaggtgtg attttcacga
     3841 caccagtacc aaactcagga tctgcgtgct catctccaac gattgggatg agtttattag
     3901 cgattggaag gatgacgttt ttaccaatca agtccttgta gcgcgggtct tctggattaa
     3961 ccgcaaccgc aacgtcccca aacatagtct caggacgagt tgtagcaact tcaagggcgc
     4021 gtgaaccatc ttccagcatg tagttcatgt ggtagaaggc accttcgaca tccttgtgaa
     4081 tcacctcaat atcagaaagg gctgtgcgag ctgctgggtc ccagttgatg ataaactcac
     4141 cacggtagat ccagcctttc ttgtaaaggt ccacaaagac cttacgaaca gcttttgaca
     4201 aaccttcgtc aagagtgaaa cgctcacgag agtagtctac agagagcccc atcttgcccc
     4261 attgttcctt gatagtagtg gcatattcgt ctttccattc ccagactttc gtcaagaaag
     4321 actcacgacc aaggtcatag cgggaaatgc cctcaccacg caagcgctcc tctaccttag
     4381 cctgagtggc aatccctgcg tggtccatcc caggaagcca aagggtatca aaaccttgca
     4441 tgcgtttttg acggatgata atatcttgca aagttgtatc ccaagcgtga ccaaggtgaa
     4501 gtttacctgt aacgtttggt ggtggaataa cgattgaata aggcttagcc ttttgatcgc
     4561 ctgaaggctt gaaaacatca gcatcaagcc atttttggta acgaccagcc tcaacctcgg
     4621 ctggattgta tttagatgaa agttctttag acatgtgtgt gtcctttctc tattttgttt
     4681 attttatttt gaatttgctt agcagcttct tctgcagaca aattcgtatt atttatttta
     4741 aagtagtggt gcaactcatt cggttgatat tgggaattta attgaagtgt ttcagcggtc
     4801 tctaaaattt ctctttcaga tacctcaata tgtcgtttta agggtttgtg ctttaatcga
     4861 ttctccgttc gatttcgacg tatgcactct tcaagacttg tttccaactc aacaaaaaga
     4921 atctcttgat gataatcatc caacaaattc tgaatttgct ttaaatatat cagatgatac
     4981 tgatttgaaa aatcaattac atctgttaaa attactgatc gctgatttct tgcacttgct
     5041 ccaaggaatg aaaaagtgat tccacgaaca aattcccaca tttcctctgt atagtcctga
     5101 tagatttcta gtgcaaaatc aatggcttga tggttataaa atagggtagc atccgtcagt
     5161 cgagataatt cttgaccaat ggtcattttt cctgatgctg gagcaccaat gatgaaaaga
     5221 tgcatcaaat caccccccac tcactcttca gcaaggcata tctcaaatca tcacagcagt
     5281 tgccttgagc atctttacgg tctcttatgc gagcttcgag ggtaaagcca agcttttccg
     5341 cgactcgttg actttgaagg ttatatccaa agcaagttag ttcaatcttg tgaagaccca
     5401 aatctttaaa ggctaagtca atcaaggcac gcgcagcttc tggcacataa cctcgccccc
     5461 aatagtctga gtgtaaggta tagccgattt ccatcacatc atcttcatgg cgatggttga
     5521 aatagataga gccaacgatc ttatccgttc ctttgacgac aatcccgtag cctgctggga
     5581 gattttcctt ttgattacgc tccggaagaa tgtgctccag ataataaatc tcatcttcca
     5641 aggtcttgac tggaggaaaa cctgctggat aggcgacctc tggcaaacta gcatagtcaa
     5701 agatatcctc agcatccgcc acagtacgga ctcgtaaaac gagacgttct gtttcgattt
     5761 tatctggcag ctcagttctt gccatccttc ttcctcgctt ttttgatgaa actgcccttc
     5821 atatctacac gcttgtccag atagcgataa acgcgctgat atccatctcc catgaaatag
     5881 gttggggcaa acagttgatt tttaaaatgt cccttttcat ccaggagttc tggggcaaca
     5941 agtcgctcaa gaatcttggc aaagatgtgg caaataccgt cttcctcaac aatcctatct
     6001 acccgacaat ctaaaacaag tggacaggcg tctaaaatag gagtctgagt tcgttcagaa
     6061 atttcataat gcactcccaa acgttccaat ttctcctgat gactgataaa accagcctgc
     6121 tccatcgcaa gcatagaagt ttcatcagaa atattcacag taaatttttg atactgtttg
     6181 atctgctctg cggcattctc tctcgcaacg actccaatca caacccaatc tcctagacta
     6241 taagaggaac tacaggtcgt gatgttatag ccaaaattct aatcttgata tcctaaaata
     6301 aaaacaggaa aaccataata tagtttactt gtgttaaaag attgcttcat aacaaccccc
     6361 tttgactaag acgtaaaaga aaagccctgc catctacatg acagggacga atgtgtttat
     6421 ccgcggtacc acccaatttc gggcagttgc ccgcaactct cgtctttaaa gcaaaaagac
     6481 acttttattt caatttttca tccattagca accagttttg acacatttgt ggacttctca
     6541 gcgccgccac tttctgtaaa atgtgggatt caaaacacct ctaatggctc tattgtagca
     6601 agattttttc ggaaatgcaa ggctcaagaa aaattacttg aacttgatgc cattttcttt
     6661 caatttcttg atggtagctg ggccgattcc tttcaagtca aggagttctt tttcagtcca
     6721 gtttttgaaa tgtgaagcag acttgattcc ttcatcatag aaagtcttgg cacgatcaag
     6781 tggaagtcca cccaaatttg ctgcaaaatc ttctacagaa ttagctactt tttgagcttg
     6841 ctctttggta gcttctactg cttgttcaac ttttttagaa acagccttac cagctgcgct
     6901 tgctgtctgt tctgcacgct tcacgacttt ttttgtctca tctacaacct tagtcacagt
     6961 acttgaaaag gcacctgcgc gacggaggcc atttcgtaat tgttttttac gattgagttt
     7021 ctttgacatg ataaaatcct ttcaataaaa aatccctgct ctgacaagga tttaacataa
     7081 acattctatc aagattttag tgaaaaatca agaatctttc tcgtttaata atttcgctca
     7141 ccaaacaagc cttctggcaa atcatggaat cccttgccta ctttgaagtt ttcaaactta
     7201 ccaagcaaga actgataagc atccaagcga ctctcgtagc gaatcatggc atctttggca
     7261 cgctcgtcct ggtcttcttc gtaaactttt tgactttcct tgtgcgccat atcgttaatc
     7321 atgatttggg tattgaccca agcttcaaat tccttcataa attcttgttc gtaactcatt
     7381 ttttctcctt attctaatcc acgaaaatag tccgtatcaa tctcacggta gggctggata
     7441 tcctgaacat actccaacac tccttggaat tctccgtctt catcgtgtac tgcagcatag
     7501 gtgatgtgga caaacttacc tcgcgactca gacttgaacc acatttcata cttgtccttg
     7561 gtcccctcac gaagtccctt catgatagcc ttgaccttgt ccaaatactt aggcggatga
     7621 cagagttcga cattgcgccc gacttgggac ggcgtccgtt tgaaaatcat ctcatcagct
     7681 ggcgtattgt cattgtaata ctggaaaata tcttctttat tgacaaaggt aatctccata
     7741 gggagatgat tgaggatgag attggcctgc tcgactgaaa gatagccatt accaaaagcc
     7801 tgttgactat ggcggtccag cacagcttcc ttttccttag gggtaaaggt aatggtaaaa
     7861 tggccttctg gcgtatctat gacttgttga acttgacctt ctgccgtatc tagttgtaca
     7921 ggctcctctg caatcttttc ctcaataaag atctgtcgtt ctggcaccca tttctctgac
     7981 ggacggatga tggcatagcc ataggcatca ctctcctccg caatctgaag ccagtcatcc
     8041 tgagtaaaag actcaaggag aatcatgagc aggatggact cttccttgaa aatcatactt
     8101 tcaaactctg tcgcaaaagc ttcaaaagct tcctttacac tgctaattga cacttctggt
     8161 agtgacttgg ctgtcgttag agctgtttga aagagttccc taatctgatc atccactccc
     8221 cacataactt tgggaggtga atcgtgtcca tagcgctcca tgataggaaa gaagagttct
     8281 tccttacgtt ggtaatggat gtcaaattga cccacaagtc ccatctgacg caccaaaccc
     8341 ttacgcatct ccgccagcat ttcctcgtct tccatagact cataggtatc taacaatcta
     8401 cgaatgcgaa tcaaggccgc acggagagcc agattttctt ctttgaagac acgaactggg
     8461 tgacctggat gctcagtatc tgaaacttcg acacctttga tagcattttt aaaaagattg
     8521 gcatggacat cacagagttc cataacatct tcaaaagtga cgcccgaatc cgagttcatc
     8581 agctcgtgct ccataaggga aatctcaatg gctgagacac ccgcaaaggt cgcatcaaaa
     8641 cgctcctgaa ccgactcagg agaggcgcca ttatgcaatt ctaataaaat atcccgtagg
     8701 acatgaatcc gttcatctgc cattagtcta atccaatcac ttcgtagcca ttcgcttcca
     8761 gtgtgcgtac aatcttgtcc ataggagttc ctgctagctt agaaccctgt ttaagtgata
     8821 ctttacgacc aactgtattg cgcattaagg gattggcaag gggtttaaaa cccaactcca
     8881 ctagaatttc caagacttct ggatgcttgt ccaccacttc tgcaacagga attgacacat
     8941 cgatgatatt gtccatgacg acctccatta tatgttctaa tactcaatga aaatcaaaga
     9001 gcaaactagg aagctagccg caggttgctc aaaacagtgc tttgagattg tagatagaac
     9061 tgacgaagtc agctcaaaac accgttttga ggttgcggat agaactgacg aagtcagtaa
     9121 catatataca gcaaggtgaa gctgacgtgg tttgaagaga ttttcgaaga gtataaaatg
     9181 attttactgc ttatattata ccatatggaa agagaataaa aaactagcag tggagttcct
     9241 gctagttctc tgcgacttgg attaccatct agataagttt aaagaaccaa tccaatatct
     9301 tgtaaaacag caattggact gcaaaagaga tgatcatcca aaagaatttc acaatcccaa
     9361 taatcggttt gataaaaata atggcaagaa gtccccagaa aaatttcatt ttttatcctc
     9421 tggcttaatg agccaccgag ccgtatccat taacttgtcg gcaataaaaa gtttccccag
     9481 accgacaacg gcattatcat ctttctttat cgttttcatt acttttacac cttgcacggt
     9541 caaaaagtaa ttaccataaa ttttagcaaa agctttgata ggattcatat tactctcctt
     9601 tgatgatttc agcctctttt cggattgttt caacatcttc ttgatattga acttcactat
     9661 agttgactag cttggataat tctttctgca agctttcccc cattggtttc atagttgcaa
     9721 aggttaaacc acctgaaatg ataccaccca agataggaat aaatttcccc attcctttgg
     9781 ccagccctcc cttggtaaga ttcacaccaa atattcttaa gactttcttc aaaataggat
     9841 accaaagcgt ctttgttaaa gctttattag gtactgtttt cattacctgt ttggcaattg
     9901 ttataccacc agcacgtagc aaagcagcag ttccattcac ccccaacatg acgcctagat
     9961 aaagcaaaag ggtattttga gcatcttcac tcaactcatc gcgtgaagcc caaagatcct
    10021 cataaccata aatataacct aattcttggg ccaatttcag agagaaacca taaaattgag
    10081 ccacatcagc tggaatggta attgccatag caagccctcc aggtaatcct gccaaaacag
    10141 aagtcccact cgctaataaa acattatccc taatacaggc attagccact cgatctaaga
    10201 tttcttgaga taagagagac gttggacctt gttccaataa ggtaggaatg tcctgtggac
    10261 ccaattcttt ggaaaactta tccactaaaa atttcgaacg atcaacctta acaacaggta
    10321 gtttcaccac ttgttgcaat acttgcatag ctaagtcttg ttcagccata tacaaactcc
    10381 ttatttcttt tttgcacctt atcatattat atttcctaca aaaaaagcat tttctaatta
    10441 gataacatta aaaaatacag aacccctttt
//
LOCUS       DAVBNZ010000071        10361 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000071 DAVBNZ010000000
VERSION     DAVBNZ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10361
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.071"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            95..343
                     /locus_tag="VQ860_001896"
     CDS             95..343
                     /locus_tag="VQ860_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120277.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            474..1646
                     /locus_tag="VQ860_001897"
     CDS             474..1646
                     /locus_tag="VQ860_001897"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET3120278.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1646..2920
                     /locus_tag="VQ860_001898"
     CDS             1646..2920
                     /locus_tag="VQ860_001898"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET3120279.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(2955..3920)
                     /locus_tag="VQ860_001899"
     CDS             complement(2955..3920)
                     /locus_tag="VQ860_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3120280.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     SYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILIIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(3901..5355)
                     /locus_tag="VQ860_001900"
     CDS             complement(3901..5355)
                     /locus_tag="VQ860_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3120281.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLIFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5731..7614
                     /locus_tag="VQ860_001901"
     CDS             5731..7614
                     /locus_tag="VQ860_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3120282.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            7763..8650
                     /locus_tag="VQ860_001902"
     CDS             7763..8650
                     /locus_tag="VQ860_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3120283.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(8693..9310)
                     /locus_tag="VQ860_001903"
     CDS             complement(8693..9310)
                     /locus_tag="VQ860_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET3120284.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(9725..9913)
                     /locus_tag="VQ860_001904"
                     /pseudo
     CDS             complement(9725..9913)
                     /locus_tag="VQ860_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         3002 a         2028 c         2307 g         3024 t
ORIGIN      
        1 attatcaatc atgaactagg attctagttt tgcaggaagt ctactacttt ccttattgtc
       61 tgtaaatcta ctgaccttgt tgtttatccc agtcatggtt tctagttcgg gctcagagtt
      121 tcaaagtgga tggcaagagc atcaattgat tgctgagaag gttagtaaaa cacttgataa
      181 gacatttgat aaggatgtca gagaaattcc gaccagtcag ttttatcaaa aatttgtaga
      241 tgagatggga aggacttact caggaaattt gatcctccag gagctgataa ctgtgaatgg
      301 agcttataaa gctacttata tcggtgaact ctctagcaac taatcattct ttaaaatgat
      361 gaccaataag aggcttgatt tggtgaatca agtctttttt ctctctttta ctgccatttg
      421 tgataaaata gtatagaacg attttttaca tgaatgataa aacagaggta aatatgacaa
      481 tcggtattga taagattggt tttgcgacca gtcaatatgt cttgaaatta caagacttag
      541 cagaagcgag gggaattgac cctgaaaaat taagtaaagg actcttactc aaggaattga
      601 gtattgcgcc cctaactgag gacatcgtga ccttggcggc cagtgctagt gactctattt
      661 taactgagca agaaagacaa gaagttgaca tggtcattgt ggcgaccgag tcaggaattg
      721 accagagtaa ggctgcggcc gtctttgtgc atggcttgct gggcatccag ccctttgctc
      781 gtagtttcga gattaaagaa gcctgctatg gggcgactgc tgccctccat tatgccaaat
      841 tgcatgtgga aaattctccg gagtccaagg tcttggtcat tgcaagtgat attgccaaat
      901 acggtattga aactccggga gaacccactc agggtgccgg aagtgtggct atgttgatta
      961 cacaaaatcc acgcatgatg gcctttaata atgacaatgt agctcagacc cgtgacatca
     1021 tggatttctg gcgaccaaat tactcgacaa ctccttatgt aaatggtgtc tattctaccc
     1081 aacaatactt ggatagtttg aaaacgactt ggcttgaata tcaaaaacgc taccagctta
     1141 ctttggatga ttttgcggct gtttgtttcc acttgcctta tcctaaatta gcgctaaaag
     1201 gcttgaaaaa aatcatggat aagagcctgc ctcaagagaa aaaagacctc ttacaaaagc
     1261 attttgacca gtctattctc tacagtcaaa aggtggggaa tatctacaca ggttcacttt
     1321 tccttggact tttgtctctc ttggaaaata cagatagctt gaaagctggg gataaaatcg
     1381 ccctttatag ttacggaagt ggagctgtgg ctgagttctt cagtggtgaa ttggttgaag
     1441 gatatgaagc ttatttggat aaagaccgct tgaacaagct caaccaacga actgtcttat
     1501 ccgttgcaga ctatgaaaag gtcttttttg aggaagtaaa cttggatgaa acaaactctg
     1561 cccagtttgc tggctatgaa aatcaagatt ttgccttggt tgaaattctc gaccaccaac
     1621 gccgttatag caaggttgaa aaataatgaa gataagttgg aatggatttt ctaaaaaatc
     1681 ataccaagag cgcctcgagc tgttaaaagc tcaggcgctc cttagtcctg agagacaagc
     1741 tagtctggag aaggatgaac agatgagcgt gactgtggca gaccagctga gtgagaatgt
     1801 agtgggaact ttttctctgc cttattcact ggttccggag gtacttgtca acggtcagga
     1861 atacaccgtt ccctatgtga cagaagaacc ctctgtggtt gcggcggcca gctatgccag
     1921 caaaatcatc aagcgtgcag gtggttttac tgcacaagtc catcagcgac agatgattgg
     1981 gcaggtagcc ctttatcaag ttgctaatcc taaactagcg caagagaaga ttgccagcaa
     2041 gaaagcggag ctcttggagc ttgccaatca agcctatcct tctatcgtta aacgtggagg
     2101 tggggcgcgt gatctgcatg tcgagcagat aaaaggcgaa ccagactttc tcgttgttta
     2161 tattcatgtc gatacccagg aagccatggg tgccaatatg ctcaacacca tgctggaagc
     2221 cttgaaacca gtcttagaag aactcagtca gggacagagt ctcatgggaa tcctgtccaa
     2281 ctacgcgacc gattctctgg tgactgcaag ctgtcgcatc gcctttcgct acttgagccg
     2341 ccaaaaggat caaggacgag agattgcgga gaaaattgcg ttggctagtc agtttgcgca
     2401 ggctgatcct taccgagctg ctactcataa taaaggaatt tttaatggta ttgatgcgat
     2461 tttgattgcc actggtaatg actggcgtgc catcgaagct ggggcccatg cctttgccag
     2521 tcgagatgga cgctatcaag gtcttagttg ctggacgctg gaccttgaaa gagaagaatt
     2581 ggtcggtgag atgaccctgc ccatgcctgt agcgactaag ggtggctcta tcggcctcaa
     2641 cccacgtgta gctctcagtc atgatctact aggaaatcct tctgccagag aattagccca
     2701 gattatcgtg tccatcggtc ttgcccaaaa ttttgcagcc ctcaaagcct tggtaagtac
     2761 gggcatccag caaggccaca tgaaactaca ggccaaatcc ctagctctcc tagctggggc
     2821 tagtgaatct gaagttgctc ccctagtaga gcgcctcatc tcagataaaa cctttaacct
     2881 agagacagcc cagcgctatc tcgaaaattt aagatcataa aaactcagac gaatcggtct
     2941 gagttttctt gtgtttaaat actttttcct ggtaatagtg taactggtaa gaagtaacca
     3001 gttgtggcga cttccttgcc ttcaatcttt tgcaagagaa gatcaatagt gagacaagca
     3061 atctcttcca aaggttgctt gatagtagcc aattgagggt agtaattttc gataaagtag
     3121 gtcccatcat agccgataac cttgagctct tttgggacag aaatgcccaa ttcttgagcg
     3181 attttaatga tcagaatagc tgtcaaatca tccgaagcaa aaatggcatc tggtttttcc
     3241 cgggtcaaga tattcttgat ttccatttct tttctgacgg gagaaaagtc actggaaaca
     3301 ttgataatag gagcttttgg gagtacggat gcaaaaccag cgtggcgcag tccggttggc
     3361 gaattggaat tgtcattccc tgtaatcatg atgatagact gggcacctgt cttgaccaag
     3421 gtttgggcag caagaacccc accagcatag ttgtcagagg agacaacagg gatgtctggc
     3481 gataggtttc ggtcaaagga aataatcggc gctgtcacac gattgtagtc ttcgattcct
     3541 aggttgtgac taccagaaat gatgccgtct acctgattgg cttccaacat ttcgatgtat
     3601 tcgcgttcct tctcagaatc atgttcactg ttgcagatga tggtcttgta accatttttg
     3661 aagagttggt gttccaattt atcaatcaat tctgcataga aaacattgga aatattgggg
     3721 aaaatcaagc cgattaactt agctgatttt ccttgcagac tacgagccag gttgttgggt
     3781 ttatagctta attctctcat ggcttcattg actttttgga tggttttctc agatagatac
     3841 ccttttttat tgataacccg agaaacggta gtaggactga cgcctgcaag tttggcgaca
     3901 tcagttagtt ttgcgaccat aatctaattc atagtaagtt ccagttgggt ttccagattt
     3961 gatcaggata ccattttggt ccgcatgtgg gaagacacga ccagaaaata ctttttctcc
     4021 tttattgatg aaaatttcaa agacagagtt atcgatgaag attgtagcag tagtagcctg
     4081 attctcgata gggcaagaac gagttgtccc aaattcttgg gcatactgtt ctccagcctg
     4141 gctacgatcc actgtcactt gaccgtttac aaggtcaaag ttgattgaaa gtcccttacc
     4201 ttctttatca gcaagtaaga caatctcgct ctggctatta gcttccaagt tgagttcaag
     4261 ttcgtaagtg ttcttggttt gggaacggtt tgagaaggct tcttcagaag cacgaaggtc
     4321 cttaatagca gcgactggat actggtagag cttgtcgtct ttgatagtga gttccttgac
     4381 caaagagaag gttccttggt gatcaaaaca gtcagatggg taagaaacat ctggcaaacc
     4441 aagccagcta actgctagag cacgcccatc aggagcgttg aaggcttgag ttgcataggc
     4501 ttcgaaaccg taatccatgt tttgaagttg agacacatct accattttgg catttttagg
     4561 gtcaaaggaa gccccaatct tatacatatt tggaaagata ttatcgtagt ctagaacttt
     4621 cttatccaat ccttgtggac agtagagaag gacaggctgt tcctctacaa agatcagatt
     4681 aggacattcc atcatgtagg cagtacggtc gttagcaaag tcaaggtcgc caactgcttg
     4741 ccagtttgtg tagtcgttat tgacagcctt gtagagacgg acgaagcctt ttttctccaa
     4801 gtcctgtcca ccgacgacag catagtattg acctttaaag ttaaaaattt gtggatcgcg
     4861 gaagtggtca gtagagtctg ctggctggtc aatcaagatc ttgtcaatct ttgtaatctt
     4921 accctccttg tccatcaaag caccgatctg gtatgggtga cggatccagt tttcatcgcg
     4981 aacatttcct gtataaaata ggaataagtt atcgccaaat tgcatggcag aaccagagta
     5041 ggcaccgtgg ctatctaatg gagtatctgg taaaactttg attccagttt ctttaaagtg
     5101 aaccaaatca tcactttcta gctgtgccca agatttcaaa ccgtgggctg caccaaaagg
     5161 aaaattctgg taaaagagga tccacttgcc atcaaagtaa gaaaagccat ttgggtcgtt
     5221 gagaagtcct gtttttggct caacatggta atgagtatgc catggagatt gtgccatatt
     5281 ttcctttata tgttgaattt cttcttgcgt ccaatcttga taaagtctgt aacgacgctc
     5341 agttgtccat tccattcatt cctccaaaaa tcttatcact tttaatagta actgttttcg
     5401 ataaaaaatg caagcctttt atgttaaaaa agaggaaaaa ctgtcaaacg attatcataa
     5461 aataaataca ggaaatcaat caaattttta cgaaaatgtg aaagataatg aaataaaata
     5521 ctttttaacc aaggtttcaa acttattttt caaggaattc ctgatgaaac agtcaaaaac
     5581 aatcaatcta aagcttgccc actaagtgga tagaatattt ttatgcaaaa cgcttgacat
     5641 atttttaaaa catgataaaa taatagtcgt aagggcgaat aaaatcgctt tcaaacaaga
     5701 acaaaatgtt atataaggag atttttgcaa atgaacaatc aggaaattgc aaaaaaagtc
     5761 atcgatgcct tgggcggacg tgaaaatgtc aatagtgttg cccactgtgc gactcgtcta
     5821 cgtgtcatgg tcaaagatga agagaaaatc aataaagaag tgattgagaa cttggaaaaa
     5881 gttcaaggtg ctttctttaa ctcagggcaa taccaaatta tctttggtac aggtacagtt
     5941 aacaaaatgt acgatgaagt tgttgtactt ggattaccaa catcatctaa ggatgacatg
     6001 aaagcagaag ttgctaaaca agggaactgg ttccaacgtg ctatccgtac ttttggtgat
     6061 gttttcgttc caatcatccc agttatcgta gcgacaggtc tcttcatggg tgtgcgtggt
     6121 cttttcaacg ctcttgaaat gccacttcca ggtgactttg caacttacac acaaatcttg
     6181 acagatacag ccttcatcat cttgccaggt ttggttgtgt ggtcaacctt ccgtgtattt
     6241 ggtggaaatc ctgccgttgg tatcgttctt ggtatgatgc ttgtctctgg ctcacttcca
     6301 aacgcttggg cagttgctca aggtggtgaa gtaacagcga tgaacttttt tggtttcatc
     6361 cctgttgttg gtttgcaagg ttccgttctt ccagccttca tcatcggggt tgtcggagct
     6421 aaatttgaaa aagctgtccg caaggttgtt ccagatgtca ttgacctctt ggtaacacca
     6481 ttcgtgacac ttttggtcat gtctatcctt ggactctttg tcattggacc agttttccac
     6541 gttgttgaaa actacatcct tattgctaca aaagcgattc ttagcatgcc atttggtctt
     6601 ggtggtttct tgattggtgg ggttcaccaa ttgatcgtcg tgtcaggtgt gcaccacatc
     6661 ttcaacttgc ttgaagtgca attacttgct gctgaccatg ctaacccatt caacgctatc
     6721 atcacagctg ctatgacagc tcaaggtgct gctactgttg cggttggtgt taaaacaaaa
     6781 aatccaaaac tgaaaacact tgctttcccg gctgctcttt ctgccttcct aggtattaca
     6841 gagcctgcta tcttcggggt gaacttgcgc ttccgtaaac cattcttcct ttcattgatt
     6901 gctggtgcaa tcggtggtgg attggcttct atccttggac ttgctggtac tggtaatggt
     6961 atcaccatca tccctggtac aatgctttat gttggtaacg gacaacttcc acaatacctt
     7021 cttatggtag ctgtatcatt tgcccttggt tttgctctta cttacatgtt tggttacgaa
     7081 gatgaagtag acgcaactgc agctgcaaaa caagctgaag tggctgaaga aaaagaagaa
     7141 gttgcgccag cagctcttca aaatgaaaca cttgtaactc ctatcgtcgg tgatgttgtc
     7201 gctcttgctg atgtcaatga cccagtcttc tcaagtggag ctatgggaca aggtatcgct
     7261 gtgaaaccaa gccaaggcgt ggtctatgca ccagctgatg ctgaagtttc aattgccttt
     7321 ccaacagggc acgcttttgg tttgaaaaca agaaatggtg ctgaagtttt gattcatgtt
     7381 ggtattgaca ctgtatctat gaacggtgac ggttttgaag caaaagttgc tcaaggtgat
     7441 aaggtgaaag ttggcgatgt tcttggaaca tttgactcaa ataaaatcgc tacagctgga
     7501 cttgatgata caacaatggt tatcgttaca aatacagctg actacgcttc agtagctcca
     7561 gtcgcaacag gttcagttgc gaagggggat gctgtgatcg aagtgaaaat ctaatcaatc
     7621 ctctctaatg tgaaaacgaa caaatgacat gtttgttcgt ttttattaga tagtaagatt
     7681 tacagaggaa aatctaaaaa atagagacat ttagactttc gaagtatgct ataataaaga
     7741 aaataaaaac aagaggttta tcatgacaaa attatatgga agcttggaag ctggcggtac
     7801 aaagtttgtc tgtgctgttg gtgatgaaaa ctttaacgtt gtagaaaaaa cacaatttcc
     7861 aacaacaact ccaatcgaaa caatcgataa aaccattgag ttcttctcaa aattcgataa
     7921 ccttgctggt cttgcagttg gttcatttgg gccgattgat attgacaaaa actcaaaaac
     7981 ttatggcttt atcacgacga ctccaaaacc aaactgggca aatgtggact tgcttggtgc
     8041 ccttcgtcgc gccctaaacg tgccaatgta cttcacaaca gacgtaaaca gctctgctta
     8101 cggtgaagtg gttgcccgta acaatgctgg tggtcgtatc gaaaacttgg tttactacac
     8161 aatcggtaca ggtatcggtg caggcgtcat ccaacgtggt gagtttatcg gtggtgtggg
     8221 tcaccctgaa atgggtcatt attatgttgc tagacaccca atggatattg aaaaagagtt
     8281 taagggtgtt tgtcctttcc ataagggatg tctggaaggc tatgcagctg gtccaagttt
     8341 ggaagctcgt acaggtgtac gtggggaaac tattgaactc aacaaccctg tttgggatgt
     8401 tcaagcctac tatatcgctc aagctgcggt taatgcgaca gtgactttcc gcccagacgt
     8461 gattgtcttt ggtggagggg tcatggctca acaacatatg ctggaccgtg tccgtgagaa
     8521 atttacatct cttcttaatg gttacctacc agtaccagat gtgcgtgact atatcgtgac
     8581 gccagcagtc gcaggaaatg gttctgccac acttgggaac tttgttcttg caaaagaagt
     8641 ttcaaaataa agcacaaaat ccgcttggga aaccaaacgg attttttacg tgtcaaagca
     8701 tttgccagaa aaagtcaata atataggtca gaccgtaggt ataaaccacg agggtaaagg
     8761 gtttggtcag aatgatgatg gtcatgtagc gcttgaaact catcttggtc agggcagcca
     8821 gcatacagag aaagtcagct gggctaatgg gccaaatcat cataaaaata aagaagcggt
     8881 caaaacgatt gcccttatct agccagccga tgtacttgtc gtaggtgcgc ttgctgacga
     8941 cagactggac aaaggcagct ccgtataggc gcactagata aaagataatg gcacagccaa
     9001 tcacgatgcc gatatagttg tagatagtcc cgatgatgtg cccgtagata aagaccccag
     9061 ccaccgaggt caaggcccct ggaatgatag ggacgacagt ctgtaaaatc tgtaaaaaga
     9121 taaagagagg tggaccccag atgcctgcct gctggataaa ggcagagagg gtttccttgg
     9181 attgtaaaat cccagcctga taagcccaaa tacagaaaat caaactccca accccaccga
     9241 caatcgatga gatattgata actcgctgca aaaggggaga aacagctttc atttgtttat
     9301 cctgtgacat gtaaactcct catagatagt atatttctac tataccatat tttggaggag
     9361 aaagggggaa tgagtctttt ttgataagga atagaaagta aatagccctt cgagacttag
     9421 aataggtctg tcaactaaag gttatatgca ttctaggttt caaataatcg caattccata
     9481 aatttaaaag cattctaagt ttcgaatagc ttatctgaga taattttgag gcattcgcgc
     9541 tttcgaatag tcattttccc taaagtttag atgtattctg aagctagaaa gactaaaatc
     9601 taaaagtagt aagagtctct ctctgatgga cgtaatttat ggctagtatg aatcctttga
     9661 attgttagtt aattttaata ttaatcagtt ctgaaataat tactaaatat agttagatgg
     9721 tgaattaatt attgctaaat ttcaagttca agttagtcat ccagaagtct tctctggggg
     9781 acttgtagtt caagcatttt ttaggatagt tgttaatcca cttttcgatg aatgcgactt
     9841 cctttgtagt cgttttctta gtttcctgag gtaactatct atgaatgagc ctgttgtgat
     9901 tttcattaga tcctataggg gtgtgcataa tagatatagc agattgaaac tagaatagta
     9961 tacatctact tctaaaacat tgttagaaat caatttgact gtcctgatca atttgtcctg
    10021 ttcttatttc attttactat ataatcctta gaaaacatat gggacaagcg gttgaattct
    10081 gttccgtcca ttagtagata aaggattact ccttcttgaa atgacagatg aacttgtttc
    10141 ttataaaaat gttgtctgaa actattagcc tttttccaga agttttagag gaagaaaact
    10201 ttacgaggaa aaaggagtta ctcaaataac aattcaggat taaaaataga cagttgagga
    10261 gcggaaggta taaattaagt ttgctgctgt ataatggatt tatcactaat actcttcgaa
    10321 aatctcttca aaccacgtca gcttcgcctt gccgtagata t
//
LOCUS       DAVBNZ010000072         9785 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000072 DAVBNZ010000000
VERSION     DAVBNZ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9785
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.072"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            198..293
                     /locus_tag="VQ860_001905"
                     /pseudo
     CDS             198..293
                     /locus_tag="VQ860_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(546..1166)
                     /locus_tag="VQ860_001906"
     CDS             complement(546..1166)
                     /locus_tag="VQ860_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3120285.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1166..1648)
                     /locus_tag="VQ860_001907"
     CDS             complement(1166..1648)
                     /locus_tag="VQ860_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET3120286.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1648..2490)
                     /locus_tag="VQ860_001908"
     CDS             complement(1648..2490)
                     /locus_tag="VQ860_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET3120287.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2585..3385)
                     /locus_tag="VQ860_001909"
     CDS             complement(2585..3385)
                     /locus_tag="VQ860_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET3120288.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3529..4908
                     /gene="glmU"
                     /locus_tag="VQ860_001910"
     CDS             3529..4908
                     /gene="glmU"
                     /locus_tag="VQ860_001910"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET3120289.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILESLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNKRLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4918..5463
                     /locus_tag="VQ860_001911"
     CDS             4918..5463
                     /locus_tag="VQ860_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3120290.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5475..5789
                     /locus_tag="VQ860_001912"
     CDS             5475..5789
                     /locus_tag="VQ860_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET3120291.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5806..6498
                     /locus_tag="VQ860_001913"
     CDS             5806..6498
                     /locus_tag="VQ860_001913"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET3120292.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIVSHEVV
                     LVESGIGKVMSAMSVAILAVHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6575..7066
                     /gene="rocS"
                     /locus_tag="VQ860_001914"
     CDS             6575..7066
                     /gene="rocS"
                     /locus_tag="VQ860_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET3120293.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7140..7730
                     /locus_tag="VQ860_001915"
     CDS             7140..7730
                     /locus_tag="VQ860_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET3120294.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7739..9502
                     /locus_tag="VQ860_001916"
     CDS             7739..9502
                     /locus_tag="VQ860_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET3120295.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            9698..>9785
                     /locus_tag="VQ860_001917"
     CDS             9698..>9785
                     /locus_tag="VQ860_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3120296.1"
                     /translation="MWYNLFMAYSIDFRKKVLSYCERTGSITE"
BASE COUNT         3032 a         1696 c         2082 g         2975 t
ORIGIN      
        1 taattttaaa gactttttga ccagcctcat ttttttaact tgatactcag tgaaaagcaa
       61 agattaaact aggaagctag ctgtaggctg ctcaaagaac agctttgagg ttgcagataa
      121 aacttgtgag gtaaccaaca tatataatgt gaagctgacg tggtttgaat agattttaga
      181 agggtatgag tctggaagtt ttaatggata atgcaagatt ccatagaatg ggtaagctag
      241 agttcttatg tgaagagttt gggcataaac ttttaccttt tcctccctac tcatattagt
      301 atagaaaagt gaatctaaaa tagtacataa ctgcttctaa aacattctta taaattgatt
      361 taaattctca aatcatatta ttcagttctt atttcatttt gctctacaat cctgttgaga
      421 agacacgtgt tcatatcaaa aaggtattgg caagttgaaa taccttttta caaggttctt
      481 ttgtcttatt tttgtttcaa ctgactatat ctcctatggt tctagttcag aaggctaggc
      541 tataattatg attgataaga agtatcattc caagtattga gagtgaatgt ttcaaaatca
      601 tgggtttcta taatggtcag gctggcattt gctagaccgc catctttacg aagaagtggt
      661 tctttatagc ctaggagagt acgaagactg gcagtaagat tggcgccgtg tccgacaatt
      721 agaatacgct cagctggact atcttttaat gatttgataa attggatggt ccgctgagtt
      781 gtactataga gggattcggc tccgaacatt cgagtgtcaa attgagcaag atttgaacga
      841 aaagcctgga tttgttgcgg gtaaatagct tccagggttg caattttcaa accttctaac
      901 ttcccaagtt gccattcacg gagattagga acgatttcta aagaacaggg ggtatggagt
      961 tgactttgga taatctcagc agatttgacc gctcgaggta aatcacttga ataaatctga
     1021 tcaaaaggaa tttccttgag atactgacca agtcgtttta gggtttcaat ggattcagga
     1081 agaagaggag aatcaccgct agcaccttga aaacgacctt cttggttcca gagggtacga
     1141 ccgtggcgga caaagtagag tttcattact tgatgtcctc caaaatatct acaaaatctg
     1201 cctttacaaa gctagccaag tcttgtggcg cgacgataat gctgtgtccg acttcgcctg
     1261 cagagacaat cattcgatcc aaatctagag caattttatc gataaaaatg ggataattgt
     1321 gtttctgacg aattccgaca ggattattgg ctccatgaat gtaaccagtt gttttttcta
     1381 agtccttttg tggaatcatg ctcacttttt tattgccaga aattttagct agtttctttt
     1441 cagacaagtg ctgagtgata gggacaattc cgataatcgg tccggtcttg tctcccaaaa
     1501 gcgccaaggt tttgaaaatc tgatctcgtt cataaccttg aggaagctct ccttctaggg
     1561 cattgatttg aatcccctga tgagggatag ctgctttaga taggatttgt tccaccaatg
     1621 tttttttgat tttaactttt tttgccatta tttatattta tcctccaatt gactcatcca
     1681 aataccaagc cagattccca gcgcaaagaa gaaggcgatg atgacataac cgacaagtga
     1741 aagtcctgtg tattggatac tttcagcgtt tcctgcattt ggaattaaga tcaaaagggt
     1801 acttgatagg acgataccga tgatgaaatg atagacgcgt gagtggtagt tgtttaaggc
     1861 ataatccatc aattttgaaa aaacgatgag agttgcacct gcaccaattc caatcggaaa
     1921 gaaggttccc aagagatcaa aagttttaaa accagtcaac ataggagcat agagtcccaa
     1981 aatcaaaagt aaattcgatg ggctgaggcc aggaaccaag acgccaaggg ccaatagtgc
     2041 gcctgctagg acgaagttaa gaaagctggc gcttaaggtt ccaacgacaa aatttaaggc
     2101 atatagtcct aatccagaaa tgataaaggt tgtccataac caagctaaat caatcttgtc
     2161 tcggtcagat tctcgagttg attctttgag gaggctagga actgtaccga taatagctcc
     2221 cgcaaagctc cataatacaa agacctgata attttcaagc aggtattcaa tcgggtagga
     2281 aaataagccg attcccagaa gcataccgat ggcaactgga ataaagtaca aaacattttc
     2341 tttaaggtct ttaaagggat gggccagaaa gccaatcatt cgttcataga ttcctaagat
     2401 tgctgctaga actcctccgg aaattcccgg taggataaat ccaagagcaa ttacaatccc
     2461 tttaataacg cgtgctaacc atgagagcat atatttcctc caactatttc tatttcaaaa
     2521 aatccttact atattgtatc acaatcagac acaaaaagaa aaagcaaatg ataaacaaat
     2581 gcttttaagg ttttaaaaaa agctttcgaa aggtttcttc tttatttttt aagggagaga
     2641 taacgttgat atctaaatcg tggtcaaagc cggcaatttt tcctttagat gtgtattggt
     2701 gaatatcata atctaaatca gttttaggac tgctctccaa aaatcctgag tctgagccgt
     2761 aggacggaat ccaaacagag gtaaacttgc ctgtatcaat actgtgttct tccatgaagt
     2821 agacaccaac gtagatgccg atgtttttag cacctagtga tgctagtttt gctcgaaagt
     2881 tttcgacacc ttcgttcata ttagacatgg ttttgtcttc cacgtcaagc caatagtaac
     2941 tagggctgta aggagaggca gcattgtaga aaacttcggc agccttttcc atttcttgga
     3001 cactttttcc agctacataa gcgtagacag caactgggac attccgcttt tgaagttcag
     3061 tgatatgact cttataggcc ttgtctattc cattgataaa tgaagcatca ttttcttttg
     3121 tcgtttgagc accactgtga acacgaacaa tagcacctga aatattttgt gagagggcat
     3181 cgtagttgat ttcctcagga cgctgccagc cagagaggtc aataatcggt ttgtctaagt
     3241 gtttcaaagc ctgtgcttca atctgtgcta tattggattt tgttttaaac gattggttgt
     3301 cattaagtgg gcgattgatg attaaaatga acatcataat cccaaaaaaa ctaaataaaa
     3361 taagtggatg aatttgtttt ctcatatctt ataattctac cctaaaaatc aaaaaaaatc
     3421 aaaaaaatgg gttaaggaag agactttaga gcattttttc attcaagagt gcggaatgat
     3481 ttgaaatatg gtataataaa agggaatttc tacagaaaag agaagattat gtcaaatttt
     3541 gccattattt tagcagcggg taaagggact cgcatgaaat ctgatttgcc aaaagttttg
     3601 cacaaggttg cgggtatttc tatgttggaa catgttttcc gtagtgtggg agctatccaa
     3661 cctgaaaaga cagtaacagt tgtaggacac aaggcagaat tggttgagga ggtcttggct
     3721 ggacagacag aatttgtgac tcaatctgaa cagttgggaa ctggtcatgc agttatgatg
     3781 acagaaccta tcttagaaag tttgtcagga cacaccttgg tcattgcagg agatactcct
     3841 ttaatcactg gtgaaagctt gaaaaacttg attgatttcc atatcaatca taaaaatgtg
     3901 gccactatct tgactgctga aacggataat ccttttggct atggacgaat tgttcgtaat
     3961 gacaatgctg aggttcttcg tattgttgag cagaaggatg ctacagattt tgaaaagcaa
     4021 atcaaggaaa tcaacactgg aacatacgtc tttgacaaca agcgtttgtt tgaggctttg
     4081 aaaaatatca ataccaataa cgctcaaggc gaatactata ttacagacgt cattggtatt
     4141 ttccgtgaaa ctggtgaaaa agttggcgct tatactttga aagattttga tgaaagtctt
     4201 ggggtaaatg accgtgtggc gcttgcgaca gctgagtcag ttatgcgtcg tcgcatcaat
     4261 cataaacaca tggtcaacgg tgttagcttt gtcaatccag aagcaactta tatcgatatt
     4321 gatgttgaga ttgcttcgga agttcaaatc gaagccaatg ttaccttgaa agggcaaacg
     4381 aaaattggtg ctgagactgt tttgacaaac ggtacttatg tagtggacag cactatcgga
     4441 gcaggagcgg tcattaccaa ttctatgatt gaggaaagta gtgttgcaga cggtgtgaca
     4501 gtcggtcctt atgctcacat tcgtccaaat tcaagtctgg gtgcccaagt tcatattggt
     4561 aactttgttg aggtgaaagg atcttcaatc ggtgagaata ccaaggctgg tcatttgact
     4621 tatatcggaa actgtgaagt gggaagcaac gttaatttcg gtgctggaac tattacagtc
     4681 aactatgacg gcaaaaacaa atacaagaca gtcattggag acaatgtctt tgttggttca
     4741 aattcaacca ttattgcacc agtagaactt ggtgacaatt ccctcgttgg tgctggttca
     4801 actattacta aagacgtgcc agcagatgct attgctattg gtcgcggtcg tcagatcaat
     4861 aaagacgaat atgcaacacg tcttcctcat catcctaaga accagtagga gcctatcatg
     4921 gagtttgaag aaaaaacgct tagccgaaaa gaaatctatc aaggaccaat atttaaactg
     4981 gtccaagatc aggttgaatt accagaaggc aagggaactg cccaacggga tttgattttc
     5041 cacaatgggg ctgtctgtgt tttagcagta acggatgaac aaaaacttat cttggtcaag
     5101 cagtaccgca aagctatcga ggctgtctct tacgaaattc cagccggaaa attggaagta
     5161 ggagaaaaca cagcccctgt cgcagctgcc cttcgtgaat tagaggaaga aacagcctat
     5221 acagggaaat tagaactctt gtacgatttt tattcagcta ttggcttttg taatgagaag
     5281 ttaaaactat atttagcaag cgatttgaca aaagtggaaa atccgcgtcc gcaggatgag
     5341 gatgaaacct tggaagtcct tgaagtgagc ttagaagaag cgaaagaatt aatccaatca
     5401 ggtcatatct gtgatgccaa gacaattatg gctgttcagt attgggagtt gcagaaaaaa
     5461 tagaggaggt cagtatgggt aaatctttat taacggatga aatgattgaa agagctaata
     5521 gaggcgaaaa aatttcaggt cctcctttgc tggatgataa tgaggaaact aagattttac
     5581 caacctcttc ttcccgtttt ggttatgcca atcctaagga tcatggtttt agccaggaaa
     5641 ccttgaagat tcaggtcgaa ccatctattc ataaaagccg tcgcattgaa aataccaaga
     5701 gaaatgtctt caattctaag ttgaataaaa tcttattcgc ggtcatcttt ctcttgattt
     5761 tgcttgtttt agcaatgaaa cttttgtaat agaaaaggaa ttgaaatgaa aataggaatt
     5821 attgctgcta tgccagaaga actggcttat ctggtccagc atttagacaa tgcccaggag
     5881 caagttgttt tggggaatac ctatcataca ggaaccattg tttctcatga agtcgttctt
     5941 gtagaaagtg gaattggtaa ggtcatgtct gctatgagtg tggcgatttt ggctgttcat
     6001 ttccaggtgg atgcccttat taatacgggt tcagctgggg cagtagcaga aggtatcgct
     6061 gttggggatg tcgtgattgc tgacaaatta gcctatcatg acgtggatgt cacagctttt
     6121 ggctatgctt atggacaaat ggcgcaacaa ccgctttatt tcgaatcaga caaaaccttt
     6181 gttgctcaaa tccaagagag tttatctcaa ttggaccaaa actggcatct tggtttgatt
     6241 gctacaggag atagttttgt tgcaggaaat gacaagatag aagcgattaa gtcccatttc
     6301 ccagaagttt tagccgtgga gatggagggg gcagctattg ctcaagcagc gcatgccctc
     6361 aatctcccag tcttagtcat cagagctatg agtgacaatg ccaaccatga agcaaacatc
     6421 ttttttgatg agtttattat cgaagctgga cgtcgctctg cccaagtctt gttgaccttt
     6481 ttgaaggctt tagattaagc ggaaatttga cagtttttct agcttatgat aagatttaag
     6541 taaagaaaag ctagaaaacg tttcagagga tattatgagt attgaaatga ccgtcagtga
     6601 gattgcagag gtcttaggat tatctcgcca agcaatcaat aaccgtgtca aagaattacc
     6661 agaagaagac acagataaaa atgacaaagg ggtaacagtt gttaccagaa gtggcttgat
     6721 taagctagaa gaaatctata aaaaaacgat ttttgaagat gagcctgtca gtgaagatgt
     6781 caaacaacgt gaactgatgg agattctagt ggatgagaag aatgcagaaa ttcttcgtct
     6841 ttatgaacaa ttaaaagcca aggatcgtca gttatcagaa aaagacgagc agatgcgtat
     6901 caaagaccgt cagattgctg agaaagacaa acaattagat cagcaacaac aattgaccct
     6961 tcaagccatg aaggatcaag aaaatcttaa gctagagctg gaccaagcaa aagaagaagt
     7021 ccaatccact aagaaaggct tttttgctcg tttatttgga ggataatcaa ggagctgttt
     7081 aggttaaatg ctaacctgat ggcttctttt gtttgtgaat agtagaggag aggtacagaa
     7141 tggaacgatt agaagattac attgcttttg acttagaatt taatcagcac gaaggacaaa
     7201 cacacttgat tcaagtatcg gcagtgcgtt ttagagatgg tcgggaaatc gatgcctatg
     7261 attcctatgt tcataccagc gtccctctaa aaagctttat caatggtttg accgggatta
     7321 cagctgagac cttaaaagat gctcctccag ttgagaaagt cttagaagaa ttccaagagt
     7381 ttgtgggttc tttgctgatg ataggctaca atgctgctaa aagtgattta cctattttag
     7441 cagagcatgg tttagactat agccaacagt acaaggtgga tttgtatgat gaagcttttg
     7501 aacgtcggag ttcagattta catggtattg ccaatctcaa attgcaaact gttgcctcat
     7561 ttcttggatt tcaaggtcag tctcataata gtttagagga tgctcggatg acggcgcgtg
     7621 tttacgaatc cttcttagag tcggatcaag ctagggaatt gttagagaca gaaagtagct
     7681 tatcaaacaa tccttttggt gtcttggact tgtctcaatt atttgactag gagtgcctat
     7741 gaaacctgaa aaacctaaaa aattgggtct taaacagatt tacctcaatc ttgataaaat
     7801 cctctttcta tttttcttga tttttatgat agtggagtat ttgtgggtac cattcaattc
     7861 atggttggct agcttcttat tagatcagac aggttatctt tttatttcct ataacaatgt
     7921 cttagccatc cttactcatt ctccattgat tagtctagct tttttagcct tgattgtaat
     7981 taaccttctg gttgcttatt ttcaaatagg actcctcttt attggtgctc gtcatctcct
     8041 ctataatgaa aagcgaaggc taattgagta tatccgcaag gttttccatg aaagttttgg
     8101 atttatgaaa aagctaactg gcgctaaagc cttgtttatc tttttctata tagctatgct
     8161 gtttcctttt atacggaaaa tgctgaagat ttattatctt aataaaatcg tcattccaga
     8221 gtttatccaa gcttatttag aagatagata ttggatgtgg tggctgagca tcctacttct
     8281 atctcttatc tttctctatg tctctgtcag attgatgttt gcccttccga agattgtata
     8341 tgatcagctg actgttcgag aagcagtgat gtttagcttg gagaaaacca agaagagagt
     8401 tactttttat gcttggaatt tattttacat cttgctcaaa gcacatttat tattttatct
     8461 tcctttgatt cctttattat tggctcaaac tttggtagat gatatcactc agagagagtc
     8521 tctgattctt ggtattttga attttgtcgt gattaaaaat ctctattata tggctctgac
     8581 ttattttttg gttaaatttg tttcattttt gacaggaaag gagctggata tgcttcctag
     8641 gagagaaaaa gatcacatcg tgcgatgggg tgtcatgact tgtgccagtc ttttctttgc
     8701 cttagaaggt tatatttatc tggaggctcc catggttcat ctacctcaac ttatttctca
     8761 ccgaggggtt tccaatgcaa atgggattca aaatacagta gagtccttgg aaactacagc
     8821 acaactcaaa ccagacttgg tggagacgga cgtgcaggaa acaaaagatg ggcagtttgt
     8881 catgatgcat gatgctaact tgaaaaatct agcaggtatc aataaaagtc ctcaagactt
     8941 aaacttggag gagcttaaag ggattgatat ttttgaaaat ggctaccaga ctaaaatttc
     9001 aagctttgaa gattatctca gtcgagccaa cgaacttggt caaaaattac taattgaaat
     9061 taaaaccagt aaaaaagata gtccagacat gatgaaccgc tttttagccc gttatgctgc
     9121 aaagctcaag atttatggac atcaaatcca gtctttagac taccatgttg tcgaaaaagt
     9181 aagacagtat gatgccgaac tgccagttta tttcatcatg ccctacaatt ctgtctttcc
     9241 taaaacaaga gcgacaggat atactatgga gtactcaacc ttggatgaat attttgtaag
     9301 caaactatgg acaacggatc agaaacttta tgtctggact gtcaatgatt cagaagctat
     9361 cagcaaatct cttcacttag gagtagatgg agtgattaca gatgatttgg aaaaagttca
     9421 gcgggaaata gaagtagccc aagaagatcc agaatatacg gatttgctct tgaaaaaagc
     9481 attggaattc tttgaatttt agtaataaaa aagaggaacg gttgttcctc ccatgatagg
     9541 taagtattct tgtgaatgct tgcttttttg tggttgcaat ccgtttacga gaattgtttg
     9601 tattgttctt gtttcaattt actttatagt gctttgaagt tggaatgcta cactataact
     9661 tataaaatat agtaaaatga accaaaaata gtacacaatg tggtataatc tttttatggc
     9721 atattcaata gattttcgta aaaaagttct ctcttattgt gagcgaacag gtagtataac
     9781 agaag
//
LOCUS       DAVBNZ010000073         9740 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000073 DAVBNZ010000000
VERSION     DAVBNZ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9740
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.073"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            89..1027
                     /gene="msrB"
                     /locus_tag="VQ860_001918"
     CDS             89..1027
                     /gene="msrB"
                     /locus_tag="VQ860_001918"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3120297.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1085..2809
                     /locus_tag="VQ860_001919"
     CDS             1085..2809
                     /locus_tag="VQ860_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3120298.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            2811..4559
                     /locus_tag="VQ860_001920"
     CDS             2811..4559
                     /locus_tag="VQ860_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3120299.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEVSREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYDNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            4816..6075
                     /locus_tag="VQ860_001921"
     CDS             4816..6075
                     /locus_tag="VQ860_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET3120300.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6151..6286
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6325..6825
                     /locus_tag="VQ860_001922"
     CDS             6325..6825
                     /locus_tag="VQ860_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET3120301.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            6901..7269
                     /gene="rplL"
                     /locus_tag="VQ860_001923"
     CDS             6901..7269
                     /gene="rplL"
                     /locus_tag="VQ860_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET3120302.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7456..7629
                     /locus_tag="VQ860_001924"
     CDS             7456..7629
                     /locus_tag="VQ860_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120303.1"
                     /translation="MQKKGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVEILVLEGQS"
     gene            7626..8222
                     /locus_tag="VQ860_001925"
     CDS             7626..8222
                     /locus_tag="VQ860_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3120304.1"
                     /translation="MKRITASQYQTSERYYKLPKLLFESERYKNMKLEVKVAYSILKD
                     RLELSLNSGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLREYGLIDEVQQSSS
                     EKGRMANKIYLGELEHEIPLVLHSDGASVKNRLGQSQKQTGPFLNSAPSETEESETDS
                     LFIEDEEERDTQPILKRKVEKVTKYDRDYIWGLVQDQF"
     gene            8259..8396
                     /locus_tag="VQ860_001926"
     CDS             8259..8396
                     /locus_tag="VQ860_001926"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120305.1"
                     /translation="MTDFERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGG
                     G"
     gene            8495..9740
                     /gene="dcm"
                     /locus_tag="VQ860_001927"
                     /pseudo
     CDS             8495..9740
                     /gene="dcm"
                     /locus_tag="VQ860_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
BASE COUNT         2900 a         1839 c         2178 g         2823 t
ORIGIN      
        1 aaccatacct acggtaaggt gacgctgacg tggtttgaag agattttcga agagtattag
       61 ttaaaaacgt gataaaggag aaataaaaat ggcagaaatt tatctagcag gtggttgttt
      121 ttggggccta gaggaatatt tttcacgcat ttctggagtg ctagaaacca gtgttggcta
      181 cgctaatggt caagtcgaaa cgaccaatta ccagttgctc aaggaaacag accatgcaga
      241 aacggtccaa gtgatttacg atgagaagga agtgtcactc agagagattt tactttatta
      301 tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg gtcgccaata
      361 tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca cagtggtgca
      421 ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat tacgccacta
      481 cattctggct gaagactacc accaagacta tctcaggaag aatccttcag gttactgtca
      541 tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg aaaagcctag
      601 tcaagaggtg ttgaaggcca gtctatctga agagtcttat cgtgtcacac aagaagctgc
      661 tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga tttatgtaga
      721 tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag gttgtggttg
      781 gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg atctgagcca
      841 tggaatggag cgaattgaag ttcgttctcg ttcaggcagt gctcacttgg gtcatgtttt
      901 cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg cttctttacg
      961 ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc cttacttaaa
     1021 caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg aatagaaggg
     1081 atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa ttttagcccc
     1141 cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga ttgctgggat
     1201 tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga ttggcctgct
     1261 ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt actcagcaaa
     1321 ggcagcagta ggttttgcta aggaattgac aaacgatctt tatcgtcata ttctttcctt
     1381 gccaaaggac agcagagacc gtctgacaac ttctagtttg gttactcgct tgacttcgga
     1441 tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttac gagcgcccat
     1501 tatcgttttt ggtgccattt ttatggctta tcgaatctca gctgagttga ctttctggtt
     1561 cttagtcatg gttgccattt tgaccattgt cattgtaggg ttatctcgat tggtcaatcc
     1621 tctctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc gccagcaatt
     1681 gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac agatttttca
     1741 aacccttaac caagtttatg ctagattaca agaaaagaca ggtttcttgt ctagtttatt
     1801 aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct ggcaaggcta
     1861 tatttcaatt caaggaggag tactcagtca aggtgctctc attgctctta tcaattacct
     1921 cttacagatt ttggtggaat tggtcaagct agccatgctg atcaattccc tcaaccagtc
     1981 ctatatctca gccaagagaa tcgaggaggt ctttgcggaa tctcccgaaa acatccattc
     2041 agaattagaa caaaagcaag ttaccagtgg tcgggtttta caagtccaag aattgacttt
     2101 tacctatcct gatgcggccc agccttctct gagagacatt tcctttgata tgactcaagg
     2161 acaaatcctt ggtatcattg gggggactgg ttctggtaaa tcaagcttgg tgcaactctt
     2221 acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg gacgtagtcc
     2281 tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg tcgaactctt
     2341 taagggaact attcgttcca acttgacttt aggtttaaat caagaagtga ctgatcaaga
     2401 actctggcaa gccttggaga ttgcgcaagc taaggatttt gtcagtgata aggaaggact
     2461 cttggatgct ctagttgaag caggagggcg aaatttctca ggtggacaaa aacaaaggct
     2521 gtctatcgca cgagcagtct tgcgccaggc tccgtttctc atcctagatg atgcgacctc
     2581 agcactggac accattacag agtccaagct cttgaaagct attagagaaa attttccaaa
     2641 catgagctta attttgatct ctcaacgaac ctcgacttta cagatggcgg accagattct
     2701 cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga tgaaatccag
     2761 tcaagtctat cgtgaaatca atgcatccca acatggaaag gaggactaga atgaaacgac
     2821 aaactgtaaa ccagacgctc aaacgtttag tcgtagattt agcaaaccat cccttcctcc
     2881 ttttcctagc ctttctagga actattgccc aagttggctt atcaatttac ctacctattc
     2941 tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt ttttggcaga
     3001 tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg gccaatcctc
     3061 tcctctataa tcgtctaatc ttctcttata ccagagattt acgagagcga atcatccata
     3121 aactccatcg gttaccgatt gcttttgcgg atcggcaagg caatggagag atggtcagtc
     3181 gtgtaaccac ggatatcgaa cagttggcag ctggcttgac catgattttt aaccaatttt
     3241 tcattggtgt tttgatgatt ttggttagta ttctagccat gctccaaatt catctcctca
     3301 tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc tttattgcca
     3361 agagatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag actcagttga
     3421 ttgaagaatc gcttagccag cagactataa tccagtcctt caatgctcaa acagaattta
     3481 tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca gccatctttt
     3541 attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat gcccttttag
     3601 ctggagtagg agcttatcgt atcatgatgg gttcaacctt gaccgtcggt cgtttagtga
     3661 cttttttgaa ctatgttcag caatacacca agccctttaa cgatatttct tcagtgctag
     3721 ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggggtctta gatagccctg
     3781 aagtggctga aacaggtaag gaagtcttga ccagtgacca agttaaggga gctatttcct
     3841 ttaaacatgt ctcttttggc taccatcctg aaaaaatttt gattaaggag ttgtctatcg
     3901 atattccagc tggtagtaag gtagccatcg ttggtccgac aggtgctgga aaatcaactc
     3961 ttatcaatct ccttatgcgt ttttatccca ttagctcggg agatatcttg ctggatgggc
     4021 aatccattta tgattataca cgagtatcat tgagacagca gtttggtatg gtgcttcaag
     4081 aaacctggct cacacaaggg accattcatg ataatattgc ctttggcaat cctgaagtca
     4141 gtcgagagca agtaattgct gctgccaaag cagctaatgc agactttttc atccaacagt
     4201 tgccacaggg atacgatacc aagttggaaa atgctggaga atctctctct gtcggccaag
     4261 ctcagctctt gaccatagcc cgagtctttc tggctattcc aaagattctt atcttagacg
     4321 aggcaacttc ttccattgat acacggacag aagtgctggt acaggatgcc tttgcaaaac
     4381 tcatgaaggg ccgcacaagc ttcatcattg ctcaccgttt gtcaaccatt caggatgcgg
     4441 atttaattct tgtcttagta gatggtgata ttgttgaata tgataaccat caagaactca
     4501 tggatagaaa gggtaagtat taccaaatgc aaaaagctgc ggcttttagt tctgaataag
     4561 ccattctctt ttgaaagttt atggacgaaa aaagttgcct tcgagtgact tttttgttac
     4621 aatagctaga aaaattgttc actgtaatac tcaatgaaaa ttaaagagca aactaggaag
     4681 ctagccgtag gttgctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt
     4741 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
     4801 gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg tgatcaagat
     4861 ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt ctatgtcggt
     4921 caagataagc cagcgttttt agagcaagct gagcagatta tagactatca gggagcttgg
     4981 attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct gagagggatc
     5041 cgagatgaca gcaatctcca tgaatggctc aatgactata tctggccagc agaatctgag
     5101 tttactcccg acatgactac caatgcggtc aaagaagccc taacagagat gctccagtca
     5161 ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca gcaaatttat
     5221 caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt ttcttcagag
     5281 acagaaacaa ctgctgagac tataagcaga actcgatcca tcatagatga aatcttaaaa
     5341 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
     5401 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
     5461 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
     5521 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
     5581 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
     5641 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
     5701 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
     5761 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
     5821 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
     5881 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
     5941 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
     6001 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
     6061 acagtagaac tttaaaagaa aaatcacgaa aaattttaaa aaaagtttgc aaaaatcttg
     6121 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
     6181 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
     6241 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
     6301 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
     6361 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
     6421 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
     6481 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
     6541 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
     6601 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
     6661 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
     6721 cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg caacgttgct
     6781 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctacacag
     6841 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
     6901 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
     6961 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
     7021 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
     7081 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat tactggtctt
     7141 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
     7201 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
     7261 cttaaataat agagtatcgc aatttaattg cggaatccct atttaccagt ctttgagagc
     7321 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
     7381 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
     7441 gtttcggagg taattatgca aaagaaagga cagtcatcac gtcaattcgt gaagagtcat
     7501 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
     7561 caagtaggtt taatccgatt tgatgaattt ggaaatgttg aaattttagt cttggaggga
     7621 caatcatgaa gcgtattacc gctagtcaat atcagacatc agagcgttat tataagctcc
     7681 ccaaactttt atttgagagt gaacggtata agaatatgaa actagaagta aaggtggctt
     7741 attctatttt aaaagatcgt ttagaattat ctctcaatag tggttggata gatgaagaag
     7801 gggcggtcta tttagtattt tctaactcta aactgatgaa gcttttaggc tgttcaaagt
     7861 caaaattact ctccatcaag aaaactttac gtgagtatgg cctaattgat gaagtccaac
     7921 agtcttccag tgaaaaaggt cgtatggcta ataaaattta cttaggggaa ttagaacatg
     7981 agatacccct agtcttacat tcagacgggg ctagtgttaa aaacagatta gggcagtctc
     8041 aaaaacagac ggggccgttt ttaaattcag cccctagtga gactgaagaa agtgagactg
     8101 attctttatt tattgaggat gaggaggaga gggatactca acctatcttg aaaagaaaag
     8161 tagaaaaggt cacaaaatat gatcgagatt atatttgggg attggtacaa gatcaatttt
     8221 gacgagaggg gttttctgaa acagccagtg aaattgctat gactgatttt gagagaatct
     8281 atcagtatgc tcttgacaat gttcgctttg ttagacgagc ggaagtactt gctgaatttg
     8341 tgtttaacgg cctatattct gtttggaata accgtgttag aaaaggaggt ggttaaatgt
     8401 cgccaatcga gtggatatta gttatgctca ttttaatttc aagtggtgtg acactttgga
     8461 cattgatagt tgttcagaaa ggggtaatca agaaatgaga tttattgatt tattttcagg
     8521 tatcggtggt tttcgacttg gaatggaaag tgtcggacac gagtgtattg gattttgtga
     8581 gattgataaa tttgctagag aatcttataa gtccattttt caaacggaag gagaaataga
     8641 atatcatgac attaaagagg taacagatca tgactttaga caatttagag ggcaagtgga
     8701 catcatctgc gggggatttc cttgccaagc tttttcactt gcaggaagac gattgggatt
     8761 tgaagatact agaggaactt tgttctttga aattgctcgg gcggccaaac aaatccaacc
     8821 acgttttctt tttcttgaaa atgttaaagg cctactcaat cacgataagg gacggacgtt
     8881 caccacaatc cttaccacat ttgatgagtt ggggtttgat gttgagtggc aggtgcttaa
     8941 cagtaaggat tttggcgttc cccaaaacag agagagggtg tttattatcg gacattctag
     9001 aaagaaaggt accagactct tatttccttt cagacgagaa ggtcaagcaa ctaactctga
     9061 gactttgaaa gcactaggaa atttgaatcc atcaaaaagt ggcgtgagcg gtaaagtgta
     9121 ttattcagaa ggtcttgcgc caactttagt tcgtggaaaa ggagaaggat ttaaggttgc
     9181 tattccttgt atgacaccag atagattaga caaaagacaa aatggtagac gctttaagga
     9241 aaaccaagag ccgatgttta ctttaaatac tcaggatcgt catggcattg tcgttgttgg
     9301 agatttaccg actagtttta aggagacagg tcgtgtctat ggaagtgagg gcttatctcc
     9361 aacactgact acgatgcaag gaggagataa aatccccaaa atactaattc cagaaccaat
     9421 ccaatttcta aaagtacggg aagcaacgaa aaaaggatat gctcaagcag agattgggga
     9481 ttcaatcaat ttggaaagac caagttctca gtatcgtcgt ggtagagttg gcaaaggtat
     9541 agctaatacg ttaacaactg tggtagagtt ggcaaaggta tagctaatac gttaacaact
     9601 agtggtcaaa tgggagtagt agtggctagc tatgaaggag aagataaaca agtttaccaa
     9661 gtagctggtg ttttaataga tggacaattt taccgtttga gaatacgacg aatcactcct
     9721 aaagagtgtt ttcgattgca
//
LOCUS       DAVBNZ010000074         8994 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000074 DAVBNZ010000000
VERSION     DAVBNZ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.075"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(358..1965)
                     /locus_tag="VQ860_001928"
     CDS             complement(358..1965)
                     /locus_tag="VQ860_001928"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET3120306.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2355..2942)
                     /locus_tag="VQ860_001929"
     CDS             complement(2355..2942)
                     /locus_tag="VQ860_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET3120307.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3070..3519)
                     /locus_tag="VQ860_001930"
     CDS             complement(3070..3519)
                     /locus_tag="VQ860_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3120308.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3524..3913)
                     /locus_tag="VQ860_001931"
     CDS             complement(3524..3913)
                     /locus_tag="VQ860_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET3120309.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3941..4567)
                     /locus_tag="VQ860_001932"
     CDS             complement(3941..4567)
                     /locus_tag="VQ860_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3120310.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4581..5144)
                     /locus_tag="VQ860_001933"
     CDS             complement(4581..5144)
                     /locus_tag="VQ860_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3120311.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5309..5543)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5597..6100)
                     /locus_tag="VQ860_001934"
     CDS             complement(5597..6100)
                     /locus_tag="VQ860_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET3120312.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6293..7123)
                     /locus_tag="VQ860_001935"
     CDS             complement(6293..7123)
                     /locus_tag="VQ860_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3120313.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7108..8790)
                     /locus_tag="VQ860_001936"
     CDS             complement(7108..8790)
                     /locus_tag="VQ860_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3120314.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETSELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
BASE COUNT         2724 a         2058 c         1636 g         2576 t
ORIGIN      
        1 tggattaaat taaaaaagta taatgtattg aatctataac agtacatctt gactgctaaa
       61 atatttctat aaattaattt gacttttctg atagagatgt tcacatctta tttcaattca
      121 ctatacaatc cagttcctaa aactttgcta gaaattgatt tggctttccg aattaatttg
      181 ttcaaatttt atttcatttc aatatactga taaatccatt cactagcaca gggcaagagg
      241 gagtcgctat tgatttcaac ggtagcaggt acatacagag gactcctacc tcagatatac
      301 tgcaatatca tcgtatgcaa aaaacctctg agatttttct caaaggttct gattttgcta
      361 attgctgttc tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg
      421 acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt caggaatttc
      481 cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaaac ctgctgcctc
      541 aaactgctca cggaaggcat tattaaactc ataacggtga cggtgacggc gttgcaccac
      601 ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag acggataaag
      661 tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca tgatatcaat
      721 gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac
      781 gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca acattggaac
      841 atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac gttgaccaaa
      901 accacctggt acgatgatcc cgtccgcatc agacaagagt tcagctacat tctctgctgt
      961 cacatcattg gcattgaccc aattgatttt aacttctaca tcattgacat agccagagtg
     1021 tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact taccaacaag
     1081 ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg accattctgt
     1141 catatccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt ccatcccttg
     1201 tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt cgataacggc
     1261 ttctggtgcc acatcacaga actgggccag tttattttta attccttgac cagctggctc
     1321 ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt ctttgacaga
     1381 gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa gcaaggttgt
     1441 atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa gagcctctag
     1501 gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa tgacatcaga
     1561 gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga tatgaggaat
     1621 gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa cttcactgta
     1681 aattttccca gttgtcacgt tggaatattt gttgagattg atatcgatga aacgttcata
     1741 gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg
     1801 gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt gaatggttac
     1861 tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc ctttcccaat
     1921 ggacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt cctctttcta
     1981 aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct actaataaga
     2041 ataatctggg acgactgcac cagattcaca actaatactc ttcgaaaatc tcttcaaacc
     2101 gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt atctacaacc
     2161 tcaaaacagt gttttgagca gcctacggct agtttcctag cttgctcttt gattttcatt
     2221 gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc taagaactag
     2281 ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat aggataattg
     2341 tcaatagcta actcttattc ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg
     2401 tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt gatttctgca
     2461 tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta tgaaagagct
     2521 ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc aatggcatct
     2581 gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc tacttcatcg
     2641 tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc ataccatgaa
     2701 cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt caactctgtg
     2761 tagaacaaag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta gttttgaatt
     2821 tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc caagatagca
     2881 cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac ttctaattcc
     2941 aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg acctcatttt
     3001 atcatttact ctttatttta cgataatttt gcggaatagt caaaggttaa gggggagaaa
     3061 gtggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg ctccattttc
     3121 cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt agatttcctt
     3181 gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac ttagaatctt
     3241 ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga gattatcctg
     3301 agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt caatccaaaa
     3361 aagctcacca tgccgatcca aataggaata catggcttcc aaggtcgctt gactgtaagg
     3421 aagcttcacc ccatctacga ggtaaaccaa gttcacatcc tgataccaag caaaagcttc
     3481 ctcacaataa ttgaccttat aataaggaac aaaacacaat gcactacctt ttcaacaaaa
     3541 gagttgctgc ttgattaaaa ccatcacacc agttatacca ttttgcttca tacccatctt
     3601 gagctaggat acgatcttct aaatcaaaaa cagagtaaat ctttctttcc tcgcaagctt
     3661 gcgcatagag atgatatagt tcatcaccac catctctatc ccactcagca gaaatcgtat
     3721 cccgacctgc caataaagcc tgataagccc tgtgatgccc atctgtaatc agcaaacaat
     3781 ctccaaaggc aagaatactg attggatcga cttggattgt ttctgccgac tggtaaagca
     3841 tctgaatatc ttgcaacttc ttttctgata aatatagttg agtcggatga agatctgcta
     3901 tattgacttt catttctttc tcctcaaggg aattcgatac tcacttctgt ttgcctttaa
     3961 atcgccattg gaagcggagc ttgtcataga agggaaactc gataaacagg actcccaagc
     4021 ccacacagag actggcaagg acgtctgatg ggtaatgaac tcccagatag actcttgata
     4081 ccagcacact gactaggtag aggccaagga cgatttgtac gatttttctc cagactggat
     4141 ctttaatccg ctgactaaga ataacaatca aagtacctac catcaaggtt acagccagag
     4201 aatgcccact tgggaaggaa aatcccttct cctccaccag atgtaagata gctggtcgtg
     4261 ggcgctggta gatattttta aaggtcacga ttaaaagacc tgccaaagcc agatttccca
     4321 gcatgaagaa actttctatc ttccatcgct tacgataaaa gacaaaagct gtaatgacaa
     4381 cccaagtgat aatcactggg atatcaatca gacgtgtgag ggatcgaaaa agaatagtca
     4441 aataatctgg taagtctcct cgaatggcag tctgaatcga ttggtcaaaa ttgaccaaca
     4501 tttcagggta aaatttgacc atatagccaa gaataacgaa aagtaaaagg gcaaaactgc
     4561 ccttcattaa aaatgtttgt ttatctttca tagtgtttta aggttggttt caaaaggacg
     4621 tacaacaacc agaatgaaac ggaaaagatt acaccctcaa tcaagttaaa aggtaatacc
     4681 atggtcatta ggtagttgga aagtcccaaa atttttccaa tatcaaagtt agcaaactta
     4741 gcgtacaaag gaacagcata aacatagttg agaaccaaca tggccaaggt taaaccaaca
     4801 gttccagcta gagagcctag taggaaacga agggttgtcc gttccttttt ccaaatcaaa
     4861 gcaaatacga tgacaaaaac tcccaaagct acgatattca tcggcaaacc aatgtaagta
     4921 ttcactcctt ggctgttaag aagcaatttc aatagtgagc gaagcaagag cactcctaga
     4981 gcagcaggca aatccatgac caccagaccc acaaggactg gcaagatact aaattcgatc
     5041 ttgaggaaag atgccgctgg taaaagcgga aagtcaaagt acatcagcac aaatgagatg
     5101 gctgataaaa ttgcaatggt cgaaagtcga cgtgtgtttg tcataacagg ttcctccaat
     5161 tttctataaa atcagaagaa gttggaaagg attcctctat ctattctcac tttttatatc
     5221 ccaaaagttc cctcttactc tattaaagaa aaacaaagca agtggttaca atccggctat
     5281 aaatctatca aaacagacaa agctattctt tcgtcttctc ccatccagac tatactgtcg
     5341 gttgtggaat ctcaccacat cagcttgcgc tcgcggactt ctttaaagag aaggaaatag
     5401 agatttttct tttagactag gcgacaagct gtaggcataa cttctggtta ggcaaagctt
     5461 gtcaacaaag tataaaagga aaagatcatt tcctagttaa agtcaccgcc ggtcgggaat
     5521 cacaccctgc cctgaagact cttttatcat aacaaaaaac gcttgcaagc gcaagcattt
     5581 tgttcatttt cattttttat ttcaatttat ccacttcata ggtatggacg agctcaagac
     5641 ctgcaaagtt ctgctggcga agagcctcat agacaatcat gcagacggta ttagacacat
     5701 tgagactgcg gacatgttca tcattcatgg gaatacggag agccttctca ggatgttctc
     5761 gcataaaatc ttcaggtaag cccttgtctt cacgtccaaa gagaaaataa tggtcctcgt
     5821 cagtcgataa atccacctca gaatagactt tttccgcgaa tttcgaaatc agatagagtt
     5881 ttcccttcat ctgagatatg aaatcttcca aactctcgta aaaataaatc tctagcttat
     5941 cccagtaatc caatccagcc cgcttcatct tgcggtcatc aataggaaag cccataggct
     6001 tgatgatgtg gaggggagaa ttggtcgcag cgcaagtacg cgcgatattg cccgtatttt
     6061 gtggaatttg aggttcaaat aatacaatgt gatttgtcat gacttgcttc ctttcaccat
     6121 tgcaaaaaaa tagccacact gcccggagtc aagctcagca aacagcgtgg ttaaggcatc
     6181 gttaacttac ctcacaacag gtttgaagta aatcagcgaa actactttct tagtataaca
     6241 ctttcagaat cattgtcaat agaaatgact tgattttttc aattttttca agctatttcc
     6301 aagggttata aaatcgtccc tgattctgca agataagtag taaactaact actaaaaaca
     6361 aggttgccaa gagcaaggta atatagtctc cttttttcaa ggcctgataa ctataccatg
     6421 tgcgtttttt ctctttccca aagcggcgaa gctccatggc agtcgcaatg gtatcaatgc
     6481 gttctagcga gctaaaaatc aagggcgtaa taatgagcag attgcctttg attcgttgca
     6541 taagagaagc tttcttggat aattccatcc cacgcgcctc ctgagacatc ttgatagtaa
     6601 agaattcttc ctgcaaatct ggaatatagc gcaaggtcag gctgacagaa taagcaatct
     6661 tatagggcac accaatttga tttaaactgg aagcaaactg actaggatgg gttgtcatca
     6721 aaaagataat agccagagga atggtgcaaa gatacttaat ggccaaattt agcagataaa
     6781 agagctcctg gctggttaga gtgtagacac cgattccctg ccaaatcaca cttctctctc
     6841 cataaagtcc aaccccatac tcgggagaaa agagatagac catcaaaacg tttaaaacgg
     6901 caaataccgt cgcaaaaacg gctacaaagg aaacatcttt aaagcgaatt tctgataaat
     6961 agaggagaaa gactgaaaag atggcaatca gcaagagcat tctggtatca tagctaatca
     7021 tggccgccaa tgataccaga atgaaaaaga gaagtttccc agctcctgac aagcgatgaa
     7081 tcacagtatc tctatgctgg taaccgatta atttagcttg catccctctc tcctttcttt
     7141 gtaaaatgcc gttaaatcca gtggatccac atctagtttc ttagccaagt taaagatgga
     7201 ggtttctttt agattggctt ttactaacag ctcaggatcg ctcaacagac tggctggaac
     7261 agtatcggca atcaattctc catccaccat gacaaggacc cggtctgaat aatccagcat
     7321 caattgcata tcatgggtaa tcatgacaat ggtatgccct ttttgatgta actcttcgag
     7381 aaattccata atctcagtat agttcttctg atcttgacct gcagtcggtt catctaggag
     7441 aataatttca gctcctaaga ccaaaattga agcaatggtg acacgttttt tctgaccaaa
     7501 tgacagggca gaaataggcc aattacggaa ttcataaagt ccacagattt tcaaggtttc
     7561 atagactctc gtttcaattt ccttctcatc cacacctcgc aaacggagcc ctagagccac
     7621 ctcatcaaaa atcatattgg ttgaaatcat ttgattagga ttttgtagca catatcctac
     7681 tcgttccgcc cgctctgcaa cagaatcgcc ttttatatcc tgtttttccc aaagatagcg
     7741 tccttccgtc tgaataaagc tacttatagc cttggctaga gttgatttcc ctgctccatt
     7801 ttttccgaca atagcaatct tttcaccctt tttaatatct aaatgtaggg attttaaaat
     7861 cggtctatca tcataagaaa aagatacttc ctctagtcta aagagtgact gcaattctga
     7921 ggtttctttt accagttccg tctgtaactg gacttgccct tttgagatag acaagttatc
     7981 cagatctgct aattgttctt ccttgactaa gtccacacct aattgacgga gagtggttag
     8041 ataaaggggt tctcgaattc cattttgagt caataaatca gtcgcaagca actggtcagg
     8101 gctcccatta aaaaggatac gaccatcgtt tatcaagaca atccgatcca cagggcgatg
     8161 cagaacgtcc tccaaacggt gctcgataat cagagtcgtc gtcccctctt ccttatgaat
     8221 ctggtcaatc aattcgataa tatcctgacc tgacttggga tctagattgg cgagtggctc
     8281 atcaaacaag agaatcggac tttcatcaat caagacacca gccagactga ctcgctgctt
     8341 ttgtccacct gacaaatcct gaggacgctg atccagtaaa ggaagaaggt ccagcttttc
     8401 agcccattta taaacacgac ctttcatctc atctagggct gtcacatcat tttccagagc
     8461 aaacgccaaa tcttctgcca cagacaagcc aataaactgc ccatctgtat cctgcaaaac
     8521 tgtgctaacc agatgagact tatcatagat gctcatatca aaggctactt gaccctttat
     8581 caaaaattct ccatatgtct gacccttgta aatattggga ataatcccat tcaaacactg
     8641 acccaaggta gatttacctg acccagatgg tccaacaatt aagactttct ctcccttgta
     8701 aatggtcaag tctatccctt gcaaggtcgg ttcttgttgt gtttcatacc ggaaagagaa
     8761 atccttccac tcaattatag cttctttcat cttactctct tcattcgctt cttagacttc
     8821 tattttatca taaatcaagc ccttcttgca gtctcttctc ttaaaatctt agcgccaaaa
     8881 agattcctat cctagcttac ttgcctaact aatctataaa catcgaaaaa gactagttgc
     8941 ccagccttcc ccatcatttt atactcttcg aaaatctctt caaaccacgt cagc
//
LOCUS       DAVBNZ010000075         8327 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000075 DAVBNZ010000000
VERSION     DAVBNZ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.076"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(549..857)
                     /locus_tag="VQ860_001937"
     CDS             complement(549..857)
                     /locus_tag="VQ860_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3120315.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(854..1162)
                     /locus_tag="VQ860_001938"
     CDS             complement(854..1162)
                     /locus_tag="VQ860_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3120316.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNTPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1167..2462)
                     /locus_tag="VQ860_001939"
     CDS             complement(1167..2462)
                     /locus_tag="VQ860_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3120317.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2480..3889)
                     /locus_tag="VQ860_001940"
     CDS             complement(2480..3889)
                     /locus_tag="VQ860_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3120318.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4047..4775
                     /locus_tag="VQ860_001941"
     CDS             4047..4775
                     /locus_tag="VQ860_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3120319.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5234..5428
                     /locus_tag="VQ860_001942"
     CDS             5234..5428
                     /locus_tag="VQ860_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3120320.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5793..7103)
                     /locus_tag="VQ860_001943"
     CDS             complement(5793..7103)
                     /locus_tag="VQ860_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET3120321.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7340..8212
                     /locus_tag="VQ860_001944"
     CDS             7340..8212
                     /locus_tag="VQ860_001944"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET3120322.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2589 a         1457 c         1583 g         2698 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaacg agaaaacgat gacaaggtgt gttgcttttt
      121 gatttctaaa gagtataatg atagatctct ataaaataag tgcgaaggaa atgagctttt
      181 ataatccttt cgttttaaaa tactatctca gatattctta tatcgacaag aagtttttga
      241 gtcattccct catcatacat attaaataaa tagtggctca ttcaattttt cactagaata
      301 ataagctagt atagtaaact gaaataagat ataaacaaat aaattggagc ttaacatcta
      361 tttccagcaa ttttttagaa attgcagtgg actattctag attcaataca ttataaaaac
      421 tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga tccaatcctt tcaatcattt
      481 tgtccaactt ttggaggttc ctacaatgta gccgtcatta ataaagacag atgggaacga
      541 cagtgttcct atttattttg atagagatcg atgaattctt tagatagcaa ctgaataatc
      601 tctgttgaag ccatttggtc ttctgcatgc ataaatagca aggagaatcc tattttttct
      661 ccagtagctt ctttttgtat gagattagag tgaatcttgt gcgcttctac taaggagtct
      721 tccgcttctt caactttaat tttcgcttct tttaaatttc ccgccttagc tagttggatg
      781 gcttcaataa aggatgattt ggctgctcca ctattggcaa tgagctgaaa acagatatat
      841 tccatttctt ctgtcatctt atttctccta tccatgcaag tgcttgttcc agaacttttg
      901 ctccattcat cattccgtaa tcccgcatat caatggtatc tacaggggta tttcctgcaa
      961 tttctttcac agcaagtaac tcataacgaa tttgtggccc aattagaatg acatctgctt
     1021 catggatatt ctttttagct tctgtcattg attttgcttg gatagaaatt tcaatcccac
     1081 gttcagtcgc actttgttgc atttttttaa caagcatact tgtcgacatt cccgcattac
     1141 atactaataa aatttgtttc ataatcttaa ccttccattt cttgttcaac aactttgtca
     1201 ttaactttga taaatggaat gtatagaaga actccaagtg caaagatgat gaattgaact
     1261 agaactgctc tcacgtcccc tgctgttgct aaccatgcat ttaagaatac tggtgtagtc
     1321 caaggaactt gtataaatgc aggactcatg aatcctgtaa ctgttgctaa gtagctgatt
     1381 aaaataccaa ggactggaac tgtgataaat ggaatagcta atgaaatgtt ataaacgatt
     1441 gggtaaccga ataatactgg ttcattgata ttgaagatac caggtccaaa agataattta
     1501 gccacgtttt tagaaacagc attgcgactc actaagaatg ttgctattaa taaacataat
     1561 gtagatccac taccacccat taaagcgaat gtttgtattt gtgataagtt gatgatgtgt
     1621 ggaatggctt gtccattatt tgctgcagtg atgttttcag taatgttaat taatagtaat
     1681 ggttctagga tggcactgta aataactgct tggtgaatac caaatagcca taacatattt
     1741 cctaaagagt aaataataat gaccccgatt aagcttgtac caatatgacg aattggttct
     1801 tgaataaaga ttgtaatgat tgagattaag ttcattccag ttatattgaa taataatgct
     1861 gaaacaaccc caaataagga gatgacggtc atgactggaa gtaatacgct aaatgatcta
     1921 ctaacagctg gtggaatatt ttcaccaagg ttcatttgta aagctttaac gtttgataat
     1981 tcaatgaata attctgttgc aataatcgct acgataaccc cggcgaacat tgcgcctgta
     2041 cctgtgttgt tgaatgaaag aacacctgaa atgtttaccg catcttttgc tccgtcagga
     2101 actacagaaa ctgtatttgg catcatcaca attaaagaaa ctaatgatag cattgatgct
     2161 gctaacgggt tttcgaaatc tctgttttta gctaagaaat aaccaaccat tacagcaata
     2221 atcatacctg aaatacttaa agtaccgttt gcaattgtta ttccccaata ttggaatttt
     2281 gttaatgtat ccccttggaa aatccactta aataccgtgt tgttcaaaag aacgattaaa
     2341 cctgccaaaa tatataatgg cattactgtt acgaatgcat ctcttagggt ttttaaatga
     2401 atttggttcc ctagtttacc agcaaaggtg gcaaattgat ctataaattt tgagtttttc
     2461 atctgaatat ctcctctctt tactcctcaa tttctacttc aaaaccgtta ttgtcactta
     2521 ctttgcgata ccatcttcct gagctcttga tggttctctt ttgcgtttct aaatcaacgg
     2581 agataaatcc gtaacgattc ttatatgcat tattccaaga ccagcaatca aatgcggtcc
     2641 aagcgtggta tccaaaacag tgacttccct cttcaatggc tttatgtagc catcttaaat
     2701 gttcttcata aaattcaata cgatacacgt catcgataac tccattttca tcgataaacc
     2761 gtgcttcgtt ttcaacaccc attccgtttt cactgataaa ccatggaata ttatcatatt
     2821 cttccttcac aatcatagca atatcataaa tggctttcgg aaaaatttcc caaccacgat
     2881 atggattcat gcgacgctcc ggccattcat actctttgaa gtattggtct ggcatccagg
     2941 gcgtctgata ttcctcagga tttgcttgtg cttgaacacg ttttggatgg tagtagttta
     3001 ctccaagaaa atcaaccgta tttgatttca tcagttgaag ctctttttcg gtatgactcc
     3061 ataacacgcc atctctctct agctgtttta ccaatctttc tgggaaagtt cctttaacag
     3121 ctggattcaa gaagactttg ttaaagaagt cttctgtaaa tcgacttgct tctaagtctt
     3181 ctggagaatt acttcttgga taagcaggtg tcaagtttaa aataatccca atctttccat
     3241 caagtcctaa tgagcgatat agttgaatca cttttgcact agcaaggttt agattataga
     3301 tgacttgtac ggcctctttt ccctttcctt ttagatttgg ataatggaaa gcatataagt
     3361 atcctgcttc tggaatgacc attggctcat tgaaagttgt ccagtaatga accttatctc
     3421 caaagcatgt gaaagcagtc ttggcaaact tcacgaataa ctccactaca tgtttgcttt
     3481 cccaaccacc gtatttttga agaagttcca ctggtaaatc aaaatgatgt aaattcatca
     3541 caagatccat ctggttcttt ttagcttctt caatgatggc attgtagaaa gcaatacctt
     3601 ttggatcagg ctcacctgtc tctaaattct tgatgagtcg actccattgg atggaagtgc
     3661 ggaaagaatt aactccaatt tccttcatca agtggaaatc ttcggtgtaa gtatgaaaaa
     3721 agttactggc tacaagaggt ccgacattat cgaaaaaatc ttctggatgc gttttgaacc
     3781 agtagtccat cacattttca tgtacttttc catattgacc ttctgtctga ggtccgctag
     3841 aagcagctcc ccaccaaaac agattaggaa atactaactt ttttttcatg ctcaacctcc
     3901 tttctattat tctatacata aagtatagca taattttaaa atttgtctag acatttttaa
     3961 aaattgttga tacatatctt gtgtttgcct catttcttga actttgttat actactatta
     4021 gaatattata gagagaacca gattaaatga gtacaaaata tttatttatt tacaatgaga
     4081 ttcgtgaaaa gattctttgt aataaatata ccatgaacga acaattgcct gatgaaatga
     4141 cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa aaaagcttta gacttgttag
     4201 tttctgaggg cttaattttt agaaaacgtg ggcagggaac ctttgttctc tctcgtggca
     4261 gctcaaaaag aaaattaatc gttccagaaa gagatatccg gggactgaca aaaatatctg
     4321 aagatgctca ttctacaatt gactcgagga ttattcactt caaattagaa tttgcaaatg
     4381 aatttttagc agaaaaacta caggtcgctt tgcagagtcc agtttataat atttaccgtc
     4441 tgcgtattat tgacggtaaa ccttatgttc tggaacaaac ttatatgagt accgatgtta
     4501 ttccaggtat tactgaagat attttacaaa aatcgattta caattacatt gaaggaaagt
     4561 taggattgca tattgccagt gctacaaaaa tcttgcgagc ttcttctagt tcagaaaatg
     4621 agcaacatta cttgcagctc cttccaacgg aaccggtatt tgaagtagaa caagtggctt
     4681 atttggataa cggaactccg tttgagtact cgattagtcg tcatcgctat gatttatttg
     4741 aatttaattc ttttgcatta cgacattcct cctaggagaa aatgtgaaaa tgaagccaat
     4801 cttttacaga ctctagttta agaaaaattt aaaacagggc aagaaggtcc catctatgct
     4861 taaatggttt ctcttttcta aataagatgg ctttaaaaga gtgatcgttt tatccatcat
     4921 gttgaaaaat atcttcgtat agcttataga gtaggtactg aaattgttca cctgatctac
     4981 ttcttatagt tatttagttt taaatagtgt ttcaaacatt cttacactga cgagaagttt
     5041 ttgagtcttt tcttgtaaca catatagtat actgaggtta gaatagtaga ctgtgacttc
     5101 taaaaaattg ctagaaatga atttcaatct cccaatttat ttgttcatat cttcttttaa
     5161 tatattaaat aaattctgaa tcataatcat ttaaaaaaat tttatttttt atttttcatt
     5221 acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt ttgctattag
     5281 ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc atcgtatatt
     5341 gtttgataat atttcttttg atacttcgag ttcaggcgtg acattaatta ctggtaaaaa
     5401 tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac acatctactt
     5461 ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt tcttatttca
     5521 tttcactata tctcaaattg agtatgacga agtgcgctcc catgtcctgg gaacgcactt
     5581 cgtcatattt ttcatattct tgaatccatc gataaagact attgggatga atttttaaag
     5641 ttgaactaat tatttttaca ggatgaggtt tacagcagag agtttgaagg ctttatcaaa
     5701 ggtttttctt ggcataatga cttttcctcg tttccactta attttgtgtc tactttatta
     5761 taccaagtcc acccttaagt tagataatga atctaactta aggaagctag aaggatgaga
     5821 atccaggtgg tcaagagtcc caaacttaag ctgataggga cacccagaat aatttgcttt
     5881 ttgaaggcaa gaccgcgttc ctctatattg gggagtgaga gttgaatgag agaaccagct
     5941 gatgaaaagg gtgagatatt agtagataga gcgccaataa cggtggctgt tgtgagtaag
     6001 tgaatatcaa tctgaggatt ttgagcactg atgatagcaa tgatgggaaa gagggctgga
     6061 gctacaacgg atagggtgga actaaagagt gacatcactc cggctatcac acaaaagaac
     6121 agaggtaacc agaaatgagg aatggttgtt gtcatgaggt gccctatcag tgtgactaaa
     6181 cctgacttga ccgctagaga cattagtaag ctcatgccgc agagcatgat aattgtagcc
     6241 cagggaactt tagccaaaat ggcttcttgc ttccctaatt tgagccttaa ggcgaggcag
     6301 accatgagta ttgagacaaa gccaatatca aatgtttttt gataagtagc tatccaggcg
     6361 atgtttggga aaatgagatg caacaaggga aaaagccaaa ccaaaaccat gctgctgatc
     6421 atgagcaagg tggtttgtct ttgaaccttg ctgaggagtg gtggttggtc aatagtcaag
     6481 gatgagtttg ttcttccctt actatagtgg ctgtaacagg ataataaaag caagacgatg
     6541 agtgggtaga taatgctgac gataaagata tgattgccaa gtgaaaaagc ttgctcttcc
     6601 catcccattt gcttaaacag gccttgaaag acaatgcctg agctactggt tatcaaatta
     6661 gcccctcctg aagctcccca attgacggct tgagctccaa tcaaagggtg tttgtccgct
     6721 ttttgacaga gggtaatcgc tagaggacag caaacggcca tagtagtgaa aaatccagca
     6781 cctaaagcag acaaaagggt tgccatcagg tataaaatca tgtagagggc gttaggatgg
     6841 gtgcgtgtgc ggtagagaat gtgttgagcc aagacatcaa gagtaccgtt agttgttgca
     6901 acgttataaa agagagagac gctaaaaatg gtaaaaaaga gtgaggttgg ccaaaaatga
     6961 agaagttctt tggggcttaa tcccatgaga gtggttgcga tgaggtaaga aaaagcaata
     7021 gccagcaggc caatattgat tttggtgcgg taaccaattc caatggctag agcaatggcg
     7081 ctaatcatta ttaaatgaat cattgaattg tcctttcagt tagaatatgg aaataggttg
     7141 gcaattttgg cgctcaaaag accacctgtt tcctattggt acttgactat tatacacaaa
     7201 aaaaatacaa ttgtcttgac aattgtattg acacttgtta gaattaaaaa tgaggtattc
     7261 aggcttgtga tttcctatgg aagttcatag tgattgcctc tagtgcttac aagtgatatt
     7321 aaaaatagag gatctagtga tgtcaatcat ttcaactgat ttaacccctt ttcaaataga
     7381 tgatacattg aaagcagcct tgcgagaaga tgttcattcc gaagattaca gtaccaatgc
     7441 catttttgat catcatggcc aagccaaggt gtcgcttttt gccaaggaag ctggtgtttt
     7501 agcggggcta accgtttttc aaagggtttt taccctattt gatgccgagg tgaccttcca
     7561 gaatcctcat caatttaagg atggggatcg tttgactagt ggcgatttgg ttttagaaat
     7621 cataggctcg gtgagaagtc tcttaacatg tgaacgcgtt gccttgaatt ttttacaaca
     7681 tttatcaggg attgcttcga tgacagctgc ttatgtagaa gccttaggcg atgattgcat
     7741 taaggtattt gatactcgaa aaactactcc taatttacgt ctttttgaga aatatgccgt
     7801 gagagttggc ggtggctata atcatcgctt taatttatca gatgctatcc tgctaaaaga
     7861 caatcacatt gcggcagtag gtagtgttca aaaggcaatt gctcaagcgc gtgcctatgc
     7921 cccttttgtg aaaatggtcg aggtggaagt ggaaagcctt gctgctgccg aagaagctgc
     7981 ggcggcgggt gctgatatta tcatgttgga taatatgtca ttggaacaga ttgaacaggc
     8041 cattacccta attgcaggac gttctcggat tgaatgttct ggaaatattg atatgaccac
     8101 tattagccgt tttcgtggtt tagcgattga ttacgtctcc agtggtagtt taacccatag
     8161 tgctaagagt cttgattttt ccatgaaggg gttaacctac cttgatgtct aagttgtaaa
     8221 ataaactaac tttttaaagg atgtctttcc tctagaacga gttttatgtc agatagttta
     8281 aacgcctctt caaatatagt aaaatgaacc aaaaatagta cacaatg
//
LOCUS       DAVBNZ010000076         7481 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000076 DAVBNZ010000000
VERSION     DAVBNZ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.077"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            154..309
                     /locus_tag="VQ860_001945"
                     /pseudo
     CDS             154..309
                     /locus_tag="VQ860_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            509..3784
                     /gene="rexB"
                     /locus_tag="VQ860_001946"
     CDS             509..3784
                     /gene="rexB"
                     /locus_tag="VQ860_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET3120323.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3781..7431
                     /gene="addA"
                     /locus_tag="VQ860_001947"
     CDS             3781..7431
                     /gene="addA"
                     /locus_tag="VQ860_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET3120324.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLERFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLSSVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2275 a         1573 c         1593 g         2040 t
ORIGIN      
        1 ttgtgtacta tttttggttc attttactat agtagattga aataagatac gaacagcttg
       61 attagggaaa tcaaattaat ttctagaaat attttagcat ccacggtgta ctattatagt
      121 ttcaatttac tatagttcaa tcattctatc aagaatattg aatatataaa ggcacgtaat
      181 attaaaactt cttctgatat cgaattagag tccgatgttg atggcgataa atcagacaat
      241 ctaccagtcg acattaagat actgggacaa cacattgaag tgtattccgt acctaagaaa
      301 caatcataaa actcaaagcc ttgttaccga ggctttttta ttatgtgatt ttcagtagcc
      361 agacttattc tatctaatac aagtaaagct aagtatttaa gatttagcag atgatgaaga
      421 aaagaaagga tggcctaaat attttaacag atttacgagg ctaatcatgg tataatatag
      481 ggtgatgaaa aattccaacg aggctgagat gaaattactt tatactgata ttcggacttc
      541 tttgacagaa attctaacaa gagaggcaga agagctagtt gcagctggca agcgggtctt
      601 ctacattgcc cccaactctc tttcttttga aaaggaacgc gccgtgctgg aatgcttgtc
      661 ccagcaggct tctttttcga ttaccgtcac gcgctttgct caaatggctc gttatctggt
      721 cttgaatgat ttaccagcta aaactactct tgatgatatc ggtcttgggt tggcctttta
      781 caaatgcctt gccgaactcg atcccaagga cttgcgtgtt tatggcgcta ttaagcagga
      841 tcctcaattg atccagcagt taattgagct ttaccatgag atgaccaaat cccagatgag
      901 ttttttggac ttggagaatt taacagatga ggataagagg gcggatttac tcttgatttt
      961 tgagaaagta acagcctatc ttaatcaagg tcagttagcc cagggaagtc agttgtccca
     1021 tttgattgag gctattgaga atgacaaggt aagtagtgat tttaatcaaa tcaccttggt
     1081 cattgacggc tttactcgtt tttctgctga ggaagagcgg gttgtggact tacttcacgg
     1141 caaaggtgtt gagattgtta tcggggctta tgctagtaag aaagcctata ccagtccttt
     1201 tagcgagggc aatctctacc aagccagcgt aaaatttctc catcatctgg cttctaaata
     1261 ccaaacgcct gctcaggact gttctcaaac tcatgagaag atggatagtt ttgacaaggc
     1321 ctctcgtttg ttggagtctt cttatgactt ttcagaactc gctttggatg tcgatgagaa
     1381 agaccgtgaa aatttacaaa tctggtcttg tttgacgcaa aaggaggagt tggagctagt
     1441 agcccgtagt attcgtcaga aattacatga gaactcagac ctgagctaca agcattttcg
     1501 tattctcttg ggggatgtag cttcttacca gttatctctc aaaaccattt ttgaccagta
     1561 tcagattcct ttttatcttg gtagaagcga agccatggct catcatccct tgactcagtt
     1621 tgtcgagtct attttagctt taaaacgtta ccgttttcgt caggaggatt tgattaatct
     1681 tcttagaact gatttgtata ctgacctcag tcagtctgat attgatgctt ttgagcaata
     1741 tatccgctat cttggtatca atggcttgcc agcctttcag caaatcttca ccaaatccca
     1801 ccatggaaaa tttaatcttg agcgtttgaa tgtcctccgc ctgagaattt tagcacctct
     1861 tgaaaccctc tttgccagcc gaaaacaaaa ggctgaaaac ctcctacaaa aatggagtgt
     1921 ctttctaaaa gaaggagctg tgaccaagca gttacaagat ttgacaacca ctttggaagc
     1981 tgtagaacag gaaagacaag ccgaagtttg gaaggctttc tgccatgttt tagaacaatt
     2041 tgcgactgtt tttgctggtt cacaggttag tctggaagac ttcctagcct tgctccattc
     2101 tggaatgagt ttgtcccaat accgtaccat tccagcaaca gtggacactg ttctggtgca
     2161 gagttacgat ttgattgcac cattgactgc tgactttgtc tatgctattg gactaactca
     2221 ggacaattta ccaaaaattt ctcaaaacac cagtcttctg acagatgaag aaaggcaaaa
     2281 cctaaaccaa gcgaccgaag aaggcgttca attactgatt gccagcagtg aaaatctcaa
     2341 gaaaaatcgc tacactatgc tttccttggt caattctgct cgtaagcagt tgttcttgtc
     2401 ggctccaagc ctttttaacg aaagtgaaag taaggaatct gcctatcttc aagagttgat
     2461 ccattttgga tttaggcgga gagagaagag gatgaatcac aaaggactgt ctaaggagga
     2521 tatggggtcc tatcacagtc ttttgtctag tctggttgcc tatcaccagc agggtgagat
     2581 gagcgatact gagcaagatt tgacttttgt caaggttctg tcgcgtgtca taggtaaaaa
     2641 actagatctg caaggtctgg aaaatccagc tatcccaacc agtccaagca gcaagacctt
     2701 agccaaggac accttgcaag ctctctatcc tgccaaacag gagttttacc tgtctacgtc
     2761 gggtttgaca gagttttatc gcaatgaata cagttatttc ctacgctacg ttttaggctt
     2821 gcaggaggaa ttacgtttgc gtcctgatgc ccgtagtcac gggaatttct tgcatcgtat
     2881 ctttgaacgc gccttacagt tgcctaatga agattccttt gaccaacgtc tagaacaagc
     2941 tattcaagaa accagtcaag aacgcgaatt tgaagctatt tatcaagaaa gtttggaagc
     3001 ccagtttacc aaggaagttt tgcttgatgt tgcacggacg actggacata ttctccgaca
     3061 caatccagcc atcgaaacca tcaaagaaga agcaaatttt ggtggaaaag accaagcctt
     3121 tattcaatta gacaatggac gcagtgtctt tgtacgaggc aaggtggacc ggattgaccg
     3181 tttgaaagct aatggagcga taggagtagt agactacaaa tccagtctga ctcagttcca
     3241 gtttcctcat ttctttaatg ggctcaattc tcagttacca acctatcttg ctgccctaaa
     3301 aagagaaggg aagcagaact ttttcggcgc catgtacttg gaaatggctg aacctgtcca
     3361 atctctgatg gcggtaaaaa gtctggcagg agcagtggta gaagccagca aatctatgaa
     3421 ataccaaggg ctcttcttgg aaaaagaaag cagttattta ggcgaatttt ataacaaaaa
     3481 caaggctaat caactgacag atgaggaatt tcagctccta ctggactaca atgcctatct
     3541 ttacaagaaa gctgctgaga agattttagc aggccggttc gccatcaatc cttatactga
     3601 aaatggcaga agcattgccc catacgtcca gcaacatcag gctattacag gctttgaagc
     3661 caattaccat ctgggccaag cccgtttcct agaaaaattg gacctagctg atggcaagcg
     3721 tctggtcgga gaaaaactca agcaagcttg gtttgaaaaa ataagagagg agttaaatcg
     3781 atgaagctta ttcccttttt aagtgaggag gagattcaaa aactgcaaga agcagaagca
     3841 aattcgagca aggaacagaa gaaaactgcc gaacaaatcg aagctatcta cacttctggt
     3901 cagaatatcc tggtctcagc atcggctggt tctggaaaga cctttgtcat ggcagagcgc
     3961 attctggacc aattggcgcg tggtgtcgaa atttctcaac tctttatctc aacctttacc
     4021 gtcaaggctg caactgaact taaagaacgt ttagagaaaa aaatcagcaa gaaaatccaa
     4081 gaaacagatg atgtcgatct caaacaacac ttgggtcgcc agttggcaga cctacccaac
     4141 gctgccatcg gaaccatgga ctctttcaca caaaaattcc ttggcaaaca tggttatctg
     4201 cttgatattg cacctaattt ccgtatttta caaaaccaaa gcgagcaact tcttctcgaa
     4261 aacgaagtct ttcatgaggt ctttgaagcg cattaccaag gtaaacagaa agagagcttt
     4321 agtcatttgc tgaaaaactt tgctgggcgt ggcaaggacg aacggggtct gcggcagcaa
     4381 gtctataaaa tctatgactt cctccaatcc accagtaatc ctcaaaagtg gctgagtgaa
     4441 tctttcctca aaggctttga gaaagctgat tttaccagtg aaaaagaaaa actgactgag
     4501 caaatcaaac aagccctctg ggatttggaa agatttttcc gttaccatct ggataacgat
     4561 gccaaggagt ttgcaaaggc tgcctattta gaaaatgttc agttaattct ggatgaaatt
     4621 ggctccctaa atcaggagtt cgatagtcag gcttatcagg cagtacttgc gcgtgttgtc
     4681 gccatctcta aggagaaaaa cggtcgtgct ctgactaatg ccagccgtaa ggctgatttg
     4741 aagcccctgg ctgatgccta caacgaagag agaaagaccc agtttactaa actaggacaa
     4801 ttatcagacc agatagcgat tctcgactat caagaacgtt atcatggaga cacttggaaa
     4861 ctagctaaaa ccttccaatc tttcatgagc gattttgtag aggcttatcg tcagagaaaa
     4921 cgacaggaaa atgcctttga attcgctgat atcagccatt acaccattga gattttagaa
     4981 aatttcccac aagttcgtga gtcttatcag gagcgcttcc atgaagtcat ggtcgatgag
     5041 tatcaggata ccaaccatat tcaagaacgg atgctggaat tgttgtctaa tggccacaat
     5101 cgctttatgg tgggagatat caagcaatcc atctatcgtt tccgtcaggc agacccgcag
     5161 attttcaatg agaaattcca acgctatgcg caaaatcccc aagaaggcaa gctcattctc
     5221 ctcaaggaaa atttccgtag tagttcagaa gtgctgtcag caaccaatga tgtctttgaa
     5281 cgtctcatgg accaagaggt cggcgaaatc aactatgata acaagcacca gcttgttttt
     5341 gccaatacca aactgactcc caatccagac aacaaggcag aatttctcct ctacgacaag
     5401 gacgatacag gtgaggaaga agagagtcaa acagaaacga aactaacagg cgaaatgcgc
     5461 ttagttatca aggagattct gaaacttcat caagaaaaag gtgttgcctt taaggaaatt
     5521 gcccttctga cctccagccg cagtcgtaat gaccagattc tcctcgccct gtctgagtac
     5581 gggattcctg tcaaaactga cggagagcaa aacaattatc tccaatccct agaagtgcaa
     5641 gtcatgctag acactcttcg tgtcattcac aatcccctgc aagactatgc cttggttgcc
     5701 cttatgaagt ctccaatgtt tggttttgat gaggatgagc tagcacgttt gtcccttcag
     5761 aaagcagagg ataaagtcca cgaaaatctc tatgagaaac tggtcaatgc acaaaaaatg
     5821 gcaagtagtc aaaaaggctt gattcacaca gctctagctg aaaaactaaa gcaattcatg
     5881 gatatcctag cttcttggcg cttgtatgcc aaaacccact ctctctatga cttgatttgg
     5941 aagatttaca acgaccgttt ttattatgac tatgttgggg ctttgccgaa tggtcctgct
     6001 aggcaggcca atctctatgc cctagcactg cgtgctgatc aatttgaaaa gagcaatttc
     6061 aaaggtttgt cgcgttttat tcgtatgatt gaccaagtct tagaagccca gcacgatttg
     6121 tcaagcgtgg ccgtcgcacc gccaaaagat gcagtagagc tcatgaccat ccacaagagt
     6181 aaagggctgg agtttcctta cgtctttatc ctcaatatgg atcaagattt caacaagcaa
     6241 gactctatgt cagaagtcat tctcagtcgt cagaatggtc ttggtgtcaa atatattgcc
     6301 aagatggaga caggggcagt agaagaccac tatcctaaaa ccatcaaact ctccattcct
     6361 agtctgacct ataggcagaa cgaagaggaa ttacagctag caagctattc tgagcagatg
     6421 cgtttgctgt atgttgctat gacgcgggct gagaaaaagc tctatcttgt cggcaagggt
     6481 tctcgtgaaa agctggaagt caagcaatac ccagcagcca aaaatgggaa actaaatagc
     6541 aatactagac tgcaagcacg gaatttccaa gattggcttt gggctatcag taaagtgttt
     6601 actaaggaca agctcaactt tagttatcgt tttattggcg aagatcagtt gaccagagaa
     6661 gctatcggag agttggaaac caagagtcct ctccaagata gctcccaagc agacaatcgt
     6721 cagtcagata ccatcaaaga agctctggaa atgctgaagg aggtggaagt ttataatact
     6781 cttcaccgcg cagctattga acttcctagt gttcaaaccc caagtcaaat caagaaattc
     6841 tacgaaccag ttatggatat ggaaggtgtc gagattgctg gtcaaggtca gtcagtaggc
     6901 aagaaaatca gcttcgattt gccagatttt tcaaccaaag aaaaggtaac tggagctgag
     6961 attggtagtg ctactcacga actcatgcag agaattgacc tcagccagca actaaccctt
     7021 gctagcctaa cagaaacact caaacaagtt caaactagcc aagctgtcag agacaagatc
     7081 aatcttgata aaattcttgc tttctttgac acagtactcg gtcaggaaat tcttgctaat
     7141 accgaccatc tctatcgcga gcaacctttc tccatgctca aacgagacca aaagagtcag
     7201 gaagactttg ttgtccgtgg tatccttgat ggctatctgc tttacgaaaa caaaattgtt
     7261 ctgttcgact acaagacaga ccgctatgat gaaccaagtc aactcgtaga ccgctatcgt
     7321 ggtcagttag ctctatacga agaggcttta tcacgagcct attcgattga aaatattgaa
     7381 aaatacttga ttttactcgg taaagacgag gttcaagttg taaaagtata acttatactc
     7441 tttgaaaatc tcttcaaacc acgtcagctt cgccttgctg t
//
LOCUS       DAVBNZ010000077         7474 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000077 DAVBNZ010000000
VERSION     DAVBNZ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.078"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            52..693
                     /locus_tag="VQ860_001948"
     CDS             52..693
                     /locus_tag="VQ860_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET3120325.1"
                     /translation="MRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAGA
                     FSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLDAAYIQNGECKTSAQLLT
                     NKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYRI
                     PATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(735..2723)
                     /locus_tag="VQ860_001949"
     CDS             complement(735..2723)
                     /locus_tag="VQ860_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3120326.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2725..3483)
                     /locus_tag="VQ860_001950"
     CDS             complement(2725..3483)
                     /locus_tag="VQ860_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3120327.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            3911..4102
                     /locus_tag="VQ860_001951"
     CDS             3911..4102
                     /locus_tag="VQ860_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120328.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4456..4728)
                     /locus_tag="VQ860_001952"
     CDS             complement(4456..4728)
                     /locus_tag="VQ860_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3120329.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(4787..5236)
                     /locus_tag="VQ860_001953"
     CDS             complement(4787..5236)
                     /locus_tag="VQ860_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET3120330.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLINQPED"
     gene            complement(5223..7352)
                     /locus_tag="VQ860_001954"
     CDS             complement(5223..7352)
                     /locus_tag="VQ860_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET3120331.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         2210 a         1562 c         1472 g         2230 t
ORIGIN      
        1 tcagaaacaa atcacgaaat cgattcaaat tttgcaggtc gtttaaatat cctgcgcgca
       61 ggtgttcttg gtgctaacga tggaattatt tccattgctg gtgtggttat cggggttgcc
      121 agtgccacga ccaatatctg gattatcttt ttatcaggat ttgcggctat cttagctggt
      181 gccttttcaa tggctggtgg agaatatgta tccgtttcaa ctccaaaaga taccgaggaa
      241 gctgccgttt cgcgagaaaa actcttgtta gaccaagata gggaactagc caaaaaatcc
      301 ctcgatgctg cttatatcca aaatggagaa tgcaaaactt ctgcccaact cttgaccaat
      361 aagatctttc ttaaaaatcc actcaaggct ctggtagagg aaaaatatgg gattgagtat
      421 gaagaattta ccaatccttg gcacgctgcc atttctagct tcgttgcctt tttccttaga
      481 agtttgcctc caatgctgtc agtgaccatt tttccaagtg attaccgcat ccctgctact
      541 gtccttattg tcggtgtggc ccttcttctc actggttaca ctagtgccag acttggaaag
      601 gatccgacta gaacagctat gattcggaac cttgctattg gtctcttgac catgggagtt
      661 accttcctgc tcgaacaact tttcagcatt tagaatacaa gaaatacctc gattttgaag
      721 tcgaggtatc ttttttacat ttgcacaatc ttgcgataac ttcttgaagt aatcatgaaa
      781 atcagcacat aggcgatgag gaagatagcg cagatagaca aggtcacaat caacatcata
      841 gtcgtatcca gtacaccaat cacttttaaa atcaggctaa gcatatggta ggcaaaggcg
      901 agatgtatga aggcaaagag caaaggaagg aagaaaacag ttaaaacctg tttgttgatg
      961 gtttgcttga tttgcttttg gtccaaacca actttctgca agataataaa gcgttcacgg
     1021 tcttcgtagc cttcagaaat ttgtttgtag tagatgacca gaacagttcc gaccataaag
     1081 ataatggata ggaaaatacc gataaagaag acaccaccaa agagggcact catctgagaa
     1141 ctagcatctg ctagattgct accataaaca tagctacctt ctgtgtctaa ttgagcatta
     1201 aattgattga ggtagttttc atactcctca gcgaccttga gttgttcttc ttcgctggca
     1261 tctacattca taccaccgta aaactgatta tagatagccg aatctgggaa ttgatccaaa
     1321 aaggcttgta aatcaggaac aacaaggtaa ttgtaatcag tagtcaagat attaaactta
     1381 tttggaacat ggttcacaat gaaatcttta ttaaattctt ctttgacaga aaattgatga
     1441 tcatttagag ttagagcttt ctgtcctttc agtccgtcat ttttggcaaa gagaccgacc
     1501 tcatttcctg atagagacag tttttgacca gtcatatttt cataatcttt ttggtcaaat
     1561 accatgaaaa ctgtttttgg ttggacacgg ttttgtcctt tttcaaaaat agttaacttg
     1621 gttccttctt gattcgcaac agcaaagtaa gtgtaacgaa gcacttcttt ctctttaatc
     1681 ttataacctt tgtcacttgc aaactggctc aagagtttgt ccaaatcttc tttttcaaca
     1741 ttttgccctg aaaccccaaa atcatgagga tttagaactt ttttaaagga ttctgcggaa
     1801 ttgaaaatgc ttgtcgctgc tgacatggtt accaaaacca ttgttgacaa aatagcgata
     1861 gttgctagtc caactgcatt tttcttcata cggaaaatca agttagaaac agatatgaga
     1921 ttattaggtt ggtaatagta tttcttattt ttctttaaga tttgaaggaa aacggtaatc
     1981 cctgcattga acaaaagata agtaccaaag ataaccagta aaacagctat gaagaaggtt
     2041 gttaaggctg taagaggatc ttttaccgta agggcaagat aatatccaat ccctaaactt
     2101 atggaaccaa gaatagtttg gagaggaagg aagcgacctt ttttctctcc gctagctttc
     2161 tcacgtgaga gctggagggc attcatacgg gcgattcgaa gggcattcag gaacatgagg
     2221 cctaggaaaa tcaaaccgaa gacaagaagt actgtaatga caactttcat ctggaaggta
     2281 gcgaccagtt ccaccttcaa tttcatcagt ttgagtagga aagcgaaaat caacttgtca
     2341 aacaaggctc caataccgat tcctgctcca acagttagaa tcccaaatag cactaactcc
     2401 ttaaaggtca tactgattag atggcgcttc tccaagccta acatgccata tatacccagt
     2461 tccttggaac ggtttttcat gacaaaacta ttggcataga ggacgataat ggctgacgca
     2521 agggtaacga caaacatacc aaatccaagt gttgcttgaa tggtggttcc tccacggatt
     2581 tccgcaatct ttggattgaa ggttagggag taaaagagat aggtgatggt gactgccaag
     2641 agaacagcca gtgcaaaggg atagtagagt ttgcggtttt taatcaagtt cgataccgct
     2701 aacttattgg ttaatcgaaa catactaatt cacctcgctt gccatgacag tcaaggtatc
     2761 agagatttct tggaacatct gacgttctgt cttctctcca cggtagattt gattgtaaag
     2821 aatgccgtct ttgataaaga gaacacgctt ggccctgcta gcagctgctg ttgagtgggt
     2881 taccatgagg atggtttgcc cacgctcatt gatttcatta aagacatcaa gtaaggctgc
     2941 agatgacttg gaatcaaggg ctcctgttgg ctcgtccgca aggagaattt caggttctgt
     3001 gatgatggcg cgggctactg ctacacgctg tttctgacca ccagaaatct cgtaagggta
     3061 cttctcttgc aattggttga tacccagatt ttcagctgtc atcaccaatt tcttcatcat
     3121 ctccgttata ggtcttcttg acaagacaag cggaagcaag atattgtcct taacagacag
     3181 agtatctagc aagttaaagt cttggaagac aaatcctagc ttttcacgcc ggaaactaga
     3241 agcctgtgaa tttttaatag ttgctgtatc agttccgttt aggtaaacct gcccacgact
     3301 tggtttatcc agcatagcta ggatattgag cagagtggat ttaccagaac cagactcacc
     3361 catgatagca acgtagtcac ccttttctac ggtgaagtga atatccttga gggcctctac
     3421 ttggttgccc tgaaaacgtg ttttataaat tttttgaacg tgttttacat ctaaaagtgt
     3481 catgagaatc tcctttctta atatcccatc aaatgaaatg tagcttgcat catagtgcat
     3541 cccagctgaa cgcgctcaat ttctttgtga cttggttttc tagttttctt atgtaagatt
     3601 tgtttcatga tgttactcct ttgttcttta tgagtctagt ttacatcaaa aaaagaccgc
     3661 ttgccataac ctaaccttac aaaagagact ttaatcttac atttttgtaa gattgggtga
     3721 aatataagca aaattactta gaaaatgatt tgatttccta tttttaaagt tgtaaaatat
     3781 aagtgtgaaa aggcttactt tgaaaaggag gaagcgggaa ctaacatttt agtaaggtta
     3841 cctagataac ataccattca atttaacact tgcaagtcgt tcaacctata aggaaagaag
     3901 gtgcgcttta atgaaacaca aagaacatat actcatcgga cttctctatc tgctctctcc
     3961 attcatcggt cagctcttag ttgaacacac acactttatc ggtacagaat ttaccggcac
     4021 tgcttatgtt atttgctggt tatcagttgt tatcagcatc caccattttt ccaaaaatgt
     4081 attgtctcag cagcaaaaat agattaaaaa actgagttta aattactgct tttataataa
     4141 aatgaaataa gaacaggaca aatcgatcag gatagtcaaa tcgatttcta acaatgtttt
     4201 agaagtagag gtgtactatt ctagttccaa tccactatag tttgtggatg aagctggcga
     4261 aatattatta atactattca aaaatcaaag tgcaaactat gtcaacttca cattgccgac
     4321 taaattacag cctgtggctg gcttcctagt ttgcactttg atttttattg agtataaaag
     4381 taaaaaagct ttaaatcaag cagtttagac tattgattta aagatttttg cttattccaa
     4441 atcttctgta gaacctcacc aaaaccagcc ttcattgtcg tcaatggctt gggcttcttt
     4501 gcgtttacgt gggcctgttc cgtacatttc tgcttcgatt tcttccttgg taggcatgat
     4561 agaagctagg atgatataga taatcacgcc aagtccaaag tttgcaactg taaaaatggc
     4621 aaacaagaaa cgaactaggg taacatcaaa attccacttg tctgacagac ctgccagaac
     4681 tcctgaaatc atgcgattgc gtctcatttt ataaaattta ctgttcatga tatttcctct
     4741 ttctgctagg ttagacatag tatatcacgg ggaggctcgg ctttcatcag tcctcaggct
     4801 gatttatcag aagcaattta cctcgacaaa gtccacagcg atagcgttgg gtatcaatcc
     4861 tacgcttgcg ctgatacctt tgctggcagg attgacaacg ataaagcttg agtggtttag
     4921 agttactatt gggcaaggat ggtacaaacc ttaatccatc cactgctttc aaaagttcct
     4981 taaaatcccg atccttgtgt tgatagccct tcccttggaa ataaaggtga taatgacaga
     5041 gttcatgtcg gacaattttc ctaaaaacct ccatacccag tttctgataa accttgggat
     5101 taaaatccag atgcccatct ttggggaaaa atcgcccacc tgtcgaacgt agacgcctat
     5161 tccactggac atgatggata aaagctctcc cgaagtcttc tagtgaaacc tgcttgacat
     5221 aatcagtcag tttcatttgg agcgaggagc gacagattaa ctttttcacg ttcagtatca
     5281 attttcttga cccaaacggt caccaaatct ccaactgaca ccacttgact agggtgtttg
     5341 ataaacttgc gactcatatg agaaatatga atcaagccgt cctcgtgaat cccgatatca
     5401 acgaaggcac cgaagtcaac aacgttacgc acaacacctt ctagcttctg acctaccact
     5461 aggtctttga tatctaggac atcttggcga agcacaggtg cgtcaaagga atcacggaaa
     5521 tctcgacctg gtttgagaag atctgcaatg atatctttaa gggtttctgg accgaggtct
     5581 agctcttgag ccatttcctt gactgaaagg gacttgagtt tgctttgggc ttcttcgttt
     5641 aggtctttaa tatctaaacg tttgaagagt tccttaactg cagtgtaatt ctctgggtga
     5701 actcctgtat tatcaaggat attgctactt tcagggatac gaaggaaacc agcagcctgc
     5761 tcaaaggcct tggctcccag acgaggaact ttcttgattt gggcgcgtga agtgattttt
     5821 ccttcttcct cgcggtattt gacaatattt tcagagatag ttttgttgag tccagctacg
     5881 tgtgaaagaa gagctgggct agctgtattg acattgacac caacttggtt aaccactgta
     5941 tcgacaacaa agtccagact ctcagatagt ttcttctgac tgacatcgtg ttggtattga
     6001 ccgacaccaa ttgacttagg atcgattttg accaattccg caagaggatc ttgcaaacga
     6061 cgggcgatag aaatggcaga gcgtttttca acggtcaagt ctggaaactc ctgacgagca
     6121 agttcgctgg cagaatagac agaagcacca ctttcattaa cgataacata gctgacttca
     6181 gggaaatctt tcagaacttc cgctacaaaa gcttcacttt cacgactggc cgttccattt
     6241 ccaatggcaa taatctctac accgtattga ccaattaaat ctgctaaatc tttcttggct
     6301 tcttcgattt gacgagctga tgctggttta acaggataaa taacctgagt tgtcagcatt
     6361 tttcctgttg catccacgac agctaacttg gcacctgtac gaaaggctgg gtcaaatcca
     6421 agaaccacgc gccctttcag tggagcaacc aagaggagat tgcgcagatt gtcagaaaaa
     6481 agttggatag ctccttcttc agctttctca gttaattctg tccgaatacg acgctcgata
     6541 gcaggcaaga cctttttctt aacggattgc tgaacaactt catcaatata agcatttttc
     6601 accttgaaac gagtagcaaa gaaggcaaga atacggtccg tcgcatgttc aaaaccgatc
     6661 ttcaagacac caagtttctc cccacgattg agagccaagg tacgatagcc ttgcatagtt
     6721 ccaactgtct ctgaaaaatc ataataaatc tgaaaaacct gcttttcatc aagactttca
     6781 tccttggctt gagaagtgag tttagagtgt ctcagcactt cctgataagt catagaacgc
     6841 aaggtcacat cttccgataa ggcttcgacc aaaatatcaa ctgcaccggt caaggcttcc
     6901 ttgccagtcg caaatccttc acagacgaac ttttcagctt ctttctctaa gtcaactata
     6961 ttctgcaaaa tcaagcgagc aagaggaaag agtccagctt cacgggcaat ggttgccttg
     7021 gtacgacgct tttccttata aggaagatag agttcttcaa cgtctgctaa tttttcggca
     7081 actaagatag cttcttccaa ttccttggtc aacttacctt gttcttgaat cttagctaag
     7141 acagcttcct tacggtcatt gagatttgtc agacttttat ccaaatcaat aatagcctta
     7201 atcgccacct catccagact accagtcatg tccttgcgat aacgcgcgat aaagggaata
     7261 gtcgcccctt cagctgtcaa acttagaacg gtatcaattt gctttaacgt cactcccaaa
     7321 tcctgagaga ttttttcata ttttttatcc ataaatctat tataccacaa gctggaaggc
     7381 tttctccaat ccttttcata ctcaataaaa atcaaaaagc aaactaggaa gctagccgta
     7441 ggctgctcaa aatactgttt tgaggttgtg gata
//
LOCUS       DAVBNZ010000078         7459 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000078 DAVBNZ010000000
VERSION     DAVBNZ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.079"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            451..636
                     /locus_tag="VQ860_001955"
                     /pseudo
     CDS             451..636
                     /locus_tag="VQ860_001955"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1248..1532
                     /locus_tag="VQ860_001956"
     CDS             1248..1532
                     /locus_tag="VQ860_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120332.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            1525..1763
                     /locus_tag="VQ860_001957"
                     /pseudo
     CDS             1525..1763
                     /locus_tag="VQ860_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1859..2077
                     /locus_tag="VQ860_001958"
     CDS             1859..2077
                     /locus_tag="VQ860_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120333.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(2449..4773)
                     /gene="pflB"
                     /locus_tag="VQ860_001959"
     CDS             complement(2449..4773)
                     /gene="pflB"
                     /locus_tag="VQ860_001959"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET3120334.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            5168..6229
                     /gene="dinB"
                     /locus_tag="VQ860_001960"
     CDS             5168..6229
                     /gene="dinB"
                     /locus_tag="VQ860_001960"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET3120335.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAENFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            complement(6376..7221)
                     /locus_tag="VQ860_001961"
     CDS             complement(6376..7221)
                     /locus_tag="VQ860_001961"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET3120336.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
BASE COUNT         2438 a         1401 c         1412 g         2208 t
ORIGIN      
        1 gaactgacga agtcagtaac atctatacgg taaggcgacg ctgacgtggt ttgaagagat
       61 tttcgaaaag tattagttaa atcttgttta atatctctac accatactat tttacatata
      121 ttatttagcg ccacatagta ctgaactctc tccaaaaacg gttatgcctc tttgaatagg
      181 gcgttatcac aagaaaagca tctccacgtt tcaacttcat atggctcaaa aacaatcaat
      241 tgatgctaaa acctgtacct agatgtttcg gttcataaaa ccatgaaact gtaaaagtgg
      301 atgaaattga tagcgatagt caaatcaaga ggcatcataa ctctaaaaag tcacaatata
      361 taagttcatc ctcggaaaaa tatcattcta attgttgaaa tggatatata aacaggggta
      421 ttaacattaa atgctcatga aacaacgaat acaggtatca aaactatgac aaaacaagtc
      481 cctaaattta ctaaagacac tgctcaactt tacacctgta aatggttgtt gtataataaa
      541 gttacaaaga tgtacgacca cactgttgta aatcatagtg ttcgcgaata tattactgat
      601 agcatttcta caaatacaat tgaagaggct ggataggctt taaacgaaat atgtcagtgt
      661 tttggcattc ctagccttaa tatcatttaa agaattgtat agataaaatt ttttccaata
      721 cagacactcg taacaactgc ttcatttttc taccaacata tttaggaaca ggataagata
      781 caagaggatt aatccataaa tcagttctat accaatctaa gacaaataag ctaaaaaaac
      841 gattgataat aagcaaatag attccaaatt ttctctatct gctcatttta ataaacaata
      901 ctagtgtaac tatccttcca gtcagaaact tgtcaaatca caccgaaaac tcttctaaaa
      961 tttatctcgt taggcaatca agcaaaaact cgacgatagt acaaacatta tcatacagaa
     1021 ttgactgcct aaattatata ctttagtaag gttttcggat aagaaaaaag gttcatttta
     1081 catttctaaa cattcttttc taagatgaaa aacagaattt ttcgattgtg atttaaagca
     1141 acaagaagat tttcagtatc atcctataga tacgagctaa ttaagaaaaa ctacattttt
     1201 gaatataaac tacaataata taaactaaat tttataggag gaagacaatg gattggtacg
     1261 attatatgat acaggcatcc aaacaatcac aattcaacgc aagccattgg tttcgctatt
     1321 tgcgaaaagt tatttttgaa gactattctt atttaacaaa ccaagatgta gaaaagttgc
     1381 tagactccaa agaactaacc cgttttcaaa aaattagctt gaagtatgcc tttcaagagc
     1441 atactccaac tcataaatat gtgatttcat taaataaacc tgctaagtta accaatgttc
     1501 aaaaattgat ggagaaatac aaacatggat aaaatgaaac cggtcttcca agccctaaat
     1561 aagaaattaa ttcaggaaaa tctgacttta acaattatgg ttatgtctta gaatatcatg
     1621 gtttacgtgc cacacaagat gttgatgctt tttatgacca aaatcagaaa atcaatgaaa
     1681 ttattgctcg tgtaggaaaa cagtttaatc ttaacatcca cgaagagtta tggctcaaca
     1741 atcatgttgc aaagcaaata tgaacaaaca acctccctta agtttatgcg aatccttgta
     1801 ctcatttgag aatctgaccg ttttagtagt ccctattgag tatgtgttag gaatgaagat
     1861 gatgagtatc agagagcagg atttgcaaga tattggtgca attattaaat acaaaaactt
     1921 tcattcacca ttcgatacct ttaaatattt aaaagacatg ggatttgata ctattgacct
     1981 ctctgttcta ttagaaggtt ttagttatgc ttatggtatg gattggttag aaaaattttt
     2041 taaagaaaat caagataaac ttcgcgaatt ttattaacag tatcaaacaa gatgattgtc
     2101 aattagccag tcgtcttatt tttatgatga aatgaaatga aataaaatcg gaacaaatca
     2161 cttagagaat tccagtcaat ttctagcact gtttgagccg tttcagcgga ctatagtaaa
     2221 atgaaataag aataggacaa atcgatcagg acagtcaaat cgatttctaa gaatgtttta
     2281 gaagtaaagg tgtactattc tagtttcaat ctattatatt tcagattcgg tccactgttc
     2341 cttcccaaaa acattgcata ttgcgccgaa ggaattgctc atactatccc aagcacaaaa
     2401 ccctcagtcg tttgaccgag ggttcctttt tattattcaa gaacttgatt agctcaatgc
     2461 atccaaggcg tcatccattg aaagaacttc gtggaagaca cgttgtgtca attcagtttt
     2521 ttgttctgga gtgaggtatt tagtgtttac acagtatcca gagatacgta cgataacgtc
     2581 ttcgcctgac atgatttttt cgtaaacatc gttcaagtcc ataacgttca agttaacgtg
     2641 ttgtccaccg ttttcgaagt aaccatcaag gattgttacc aagttatcaa cttgttcatc
     2701 acgagtctta ccaagagcgc gaggtgatac ttgtgtagtc aatgagatac cgtcagctgc
     2761 ataactaaag tcaaggctag aaagtgagtt caagttttgc aaccaaccac ctttagcttt
     2821 gttagatggg ttagcacctg gtgagaagaa ttcaagttta gacaagttca cagaaccatc
     2881 ttcgttgagg tatacacctt tgtgaactgg tgagttacca gtttgtttag agtaagcaac
     2941 gttagatgtg attgtcaaaa gtgatactgt agcttctgcg tctttgtata gtttgtggct
     3001 acgtagacga gttgtgtaag cttcgatcaa ccattctgcc aattcgtttg aacgtgggtc
     3061 atcttcaccc cagcgtgggt agtcaccgat tgtttcgtaa tcgtagatgt agccatcttc
     3121 gtcacggatt ggtttaactg tagcgtattt gatagctgac aatgtatcaa cagtgttagc
     3181 aaatccacag ataccgaatc ccatgttggc acgttgttta gttggcaaga aggccatttg
     3241 aacagcttcg tagttgtacc tatcagtcat gtagtggatg atgttcaagg catctacgta
     3301 agtgtcagtc aaccagtcaa gagatttttc aaagttcgct ttaactgatt cgaattcaag
     3361 aacttcgtca cgaataggat cgatgtcaaa tactttgtag tctttgtgaa catcgtcgta
     3421 accaccattc aaaccagtaa gaagggcttt aagaacgttt acacgagcac cgaagtactg
     3481 gatgttgtgg cgttgttctt cattttctgg atcaagtgga gacacacagc atgagataca
     3541 gctcatttca ccatatccgt ctttagccat tgttgttaca ccttcgtatt ggatagaaga
     3601 gtgtttgtgg ctcatgtgca tacagtagcg acggaagttg tatggcaatt tgtcagtcca
     3661 aagaactgtc aagtttggtt ctggtgagtt accgatgttg tcaagagtgt tcaagaaacg
     3721 gtagtccatc ttagtaacac ggtgacgacc gtcgttaccc ataccagcca tagaagttgt
     3781 gataaaggtt gggtcacctg agtacaattg gtcataagct tttgtacgag caaatttaac
     3841 tgtacgaagt ttcataacga aatcatcaac gaattcttgg atttctgatt cagtaaatgt
     3901 accacgagca aggtcacgtt ctgcaaagat gtccaatacg attggtacac gacctagaga
     3961 tgtagcagca ccgttaatca cacggcagac agccatgaaa gcaatgttaa cccattggat
     4021 tgcttctttc acgttcatcg ctggtttgcg aacatcaacc ccgtaaaggt cacccaggcg
     4081 aacaacttgt tgcaatgctt ggtattgaag gtttacttct tcacgaagac ggattgtttc
     4141 ttcatcgatt tctttgattg cattccagtc gtttactttt tcttgcatca agtagtctgc
     4201 accgtaaaga gcaagacgtg cgtaaacacc gatgatacgt ccgcgtgagt atgcatctgg
     4261 aagaccagtt acagtgtgtg catgacgagc gcgacgaata tttgaagtgt aggcacggaa
     4321 aataccgtcg ttaactgttg ttacatattt agtgaagatt tcgtgaacag ctgggtctgg
     4381 ttcgtatcca ttttctttta aagtagtttc agccatacgg ataccacctt ttggcatgaa
     4441 gttcaatttg aagagttcat cattttggat accaaagata acttcatttt ctttgtcgat
     4501 aaatccagca gggatatcag cgatagatgt tggacgagtg tccattggga aacgagtttc
     4561 ttcgtagtgt gctttagttt cttctacaat tttcttgatg tgaagtgaac gctctgttgg
     4621 tcctgcaagg aagctttcgt ctccatcata aggtgtgtag ttagcttgta caaagcgtga
     4681 tacacttgct ttttctttcc aatctacgcc tttgaagcct tcccaagctt tgtcaaaaat
     4741 atcttgtgct tcaacaaccg tcttaacaac catattaatg tcctcttttt tctagtaaca
     4801 gtcatctgtt acattcataa gacaagtata ccataaagta atcgatttca acaagtgcaa
     4861 aatccctatt tttacacttt cttttctaaa acagtctata ttttatttca aactgtatta
     4921 tatttttgaa aaaaataaag tccttttttc tttttttcag aaaaaagggt ataataaaag
     4981 aaaataagca gtaacactca atggaaatcg aaaagcaaac taggaagcta gccgcaggct
     5041 gctcaaagca ctgctttgag gttgtaaata gaactgacga agtcagctca aaatactgtt
     5101 ttgaggttgc agatggaagc tgacgtggtt tgaagagatt ttcgaagagt ataaaaaggt
     5161 gctaggcatg ttgatttttc ctttgttaaa tgatttgtca agaaaaatca tccatattga
     5221 catggatgcc ttttttgctg cggtggaaat caaggataat cctaaactca gaggaaaacc
     5281 tgtcattatt ggaagcgacc ctcggcaaac aggtggacgg ggagtcgttt ctacctgtag
     5341 ctatgaggct cgagcttttg gtgtccattc tgccatgagt tccaaggaag cttatgaacg
     5401 ttgtccccag gccgtcttta tctcaggaaa ttatgagaaa tacaaagctg tgggactcca
     5461 gattcgagct atttttaagc gctatacaga tttgattgaa cccatgagca ttgacgaagc
     5521 ctatttggat gtgacagaaa ataaactcgg tatcaagtca gcggtcaaaa ttgctcgcct
     5581 cattcaaaaa gatatctggc aagaactcca tctaactgct tctgccggta tttcctacaa
     5641 caagttctta gctaaaatgg cgagtgatta tcaaaaacct catggtttga cagtgattct
     5701 acctgaacag gctgagaatt ttctcaaaca aatggatatt tccaaatttc atggagtagg
     5761 aaaaaagaca gtagaacgtc ttcatcaaat gggcgttttt actggtgctg atttacttga
     5821 agttcctgag gtgaccctaa tagaccgttt tggtagacta ggctatgatc tgtatcgaaa
     5881 ggctcgtggc attcacaact ctccagtcaa atccaatcgc atccgtaaat caatcggcaa
     5941 ggagaaaacc tacgggaaga ttctccgtgc tgaggaagat atcaaaaaag agctgactct
     6001 tctatcagaa aaagtcgctc tcaatctaca tcaacaagaa aaagctggaa aaattgtcat
     6061 tttgaaaatc cgctacgagg acttttcaac tcttaccaaa cgaaaaagtc ttgctcaaaa
     6121 aacacaagat gctagtcaga taagccaaat agccctgcaa ctctatgaag aattaagcga
     6181 gaaagaaaga ggtgtccgcc tattggggat taccctgact ggattttaaa gctcaatgaa
     6241 aatcaaagag caaactagga agctagccgc aggctgctca aaacactgtt ttgaggttgc
     6301 agataaagct gacgcggttt gaagagattt tctaagagta taaaaccttg aagagttgcc
     6361 ccttcaaggt ttttcttata caaataaacg gacaaaactg taaagtagca aaacactacc
     6421 aagcacgata cggtatttac caaaaagggt gaagtcgtgt tttttcacat agctggtcaa
     6481 gaagcgaata gccaccatgc tgaccgcaaa agctactccc atcgcgacca agagcaaaaa
     6541 caattgccca aagctcaaga gttctccggc tttcacaaat ttgaaaatct ttaaggcact
     6601 agctccaaac ataacgggaa tcccaagata gaaggtaaat tctgtcacaa ctgaacgact
     6661 ggttccattt aacaaaccac cgacaatcgt tgcacctgaa cggctagtcc ctggtaaaag
     6721 agcaagaact tggaagagtc cgatatagaa agcggtcgta taaggaagct tgtccaactc
     6781 tgttacactt ggctcgatag cacgcgcttt attgcgcttt tccaaataga tgaaggcaac
     6841 cccgtagata atcaacatga gagcaactga aaccatgtta tggaagtggg tatcaaacca
     6901 atcatcaaat ttaaagacac caagtaaagg caaagtggca atcaagacct tcaaccatag
     6961 tctccaagtc ttacgaactt cctgtttgtc cttagtcggt ttaaaaggat tgagcttgtt
     7021 aaaataaatc accataactg ctaaaatagc accaagctga atcacgacat taaacatgga
     7081 cataaaggct tcattttgat tttggtattg gataaactcc tctgctaaaa tcaagtgacc
     7141 tgtactggaa atcggcaacc attccgtaat tccttcaaca atcccgaaga agatagattt
     7201 taaaatttca ataagataca tatatttctc cttatattat atttaacgca gttagctact
     7261 gccaaagccc aagtggtata cttggaataa gccactgtgg attagttcat ttcctccaat
     7321 cgcttgacga tttccgaaag ggtctaacaa cagctttttg tttcaattgg taatgagttt
     7381 gataacgcat agacgtttta tctcgtctaa ggtaacaagg caaaaagttc gtggataacc
     7441 aagtagactt gaaatacta
//
LOCUS       DAVBNZ010000079         7455 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000079 DAVBNZ010000000
VERSION     DAVBNZ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.080"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(173..1588)
                     /locus_tag="VQ860_001962"
     CDS             complement(173..1588)
                     /locus_tag="VQ860_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3120337.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1601..3439)
                     /locus_tag="VQ860_001963"
     CDS             complement(1601..3439)
                     /locus_tag="VQ860_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3120338.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3457..4296)
                     /locus_tag="VQ860_001964"
     CDS             complement(3457..4296)
                     /locus_tag="VQ860_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3120339.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4597..7276)
                     /locus_tag="VQ860_001965"
                     /pseudo
     CDS             complement(4597..7276)
                     /locus_tag="VQ860_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         2445 a         1569 c         1026 g         2415 t
ORIGIN      
        1 ccaatctatc ctaagttaac tatttataat cggctctctg taacaaaatt aaattaatta
       61 atccccctat aaaataaaga ggtttagaat ttgatgtctt ccaaacctct ttatttcata
      121 tttaatgaga tgctgcctta accgtgataa tatctaatca tcaataaaca aactatttga
      181 ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac attttcttat
      241 atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga ccgtacctct
      301 tagaaagctg tgcagtggac atagaaacgc agtcaataca tccccaagac gtatagccca
      361 taatttccac accatcttgt agagcttcag ctacttgcaa taaatgttct ttcatatact
      421 gaattctata atcatcttgg actgttaagt tattaaattc atcttttatt agttgatctt
      481 tagcacctaa tccgttttcc actataaata atggaatttg ataacggtca taatatctat
      541 ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactcagaa gactctaaat
      601 aaggatttac taaaccacca ataatattcc cttctcctga attatactgt gttggaagag
      661 cagattgagt cacactcatg taatagctaa aggataaaaa atctacagta taatttttta
      721 ataactctgc atcttcagct gcaaactcta tgttaatgtc attttcctta aaatatcttt
      781 ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa tttagattct
      841 catactcatg agtcgcccat acatcttttg gatttggagt cattggataa gctggcatag
      901 ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt tttgtaacca
      961 aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc gaaagattct
     1021 ccttaggtat atctattcct ccactagtaa acggtaattc caaaacagag tttacttcgt
     1081 taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt cgagcaaatt
     1141 tttcataaaa atgaatcatt ctcctatcaa tccatccatg atattttctt gctaaatata
     1201 atggagtctc atagtgtgaa agagttacaa gtggttctat cccgtgagca tgtagttcat
     1261 caaacaattc atcataatat ttcaacccag cttcgttagg ttcttcctca tctccttttg
     1321 gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt tcagaaaaca
     1381 aggatatatc ttccttatat ttatgataaa aatcaatacc tatcaatttt aagttatctt
     1441 ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc tgaactgata
     1501 agcccttacc atcttcatta tatgctccct ctacttgatt agctgcaaca gctccacccc
     1561 aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt accagtaatt
     1621 ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga aaatcattgg
     1681 tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt aaattcaagt
     1741 ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca tgactaataa
     1801 aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac tcaacaccct
     1861 catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt ttcccatcaa
     1921 atggtgcata aaccttacct tcacttggaa taatcgctac tccgtctcca attagtttat
     1981 ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat ataggagaaa
     2041 atatcatttt tttatttgaa actccagctt taacttctaa attgctagaa ctctcttctt
     2101 catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaata accgccacaa
     2161 ttaaagcatt tacaatattt gatggtacat cagaataaat aaattgaggc aacgctatca
     2221 aagatgggac agcaaataga tacgctttaa cactagtaag acctgcaaat aatcccgcta
     2281 atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc acaccatata
     2341 atgcaggttc ggtaatccct gcaagtaagg ctgagaaacc tgctgcaaaa gcaatttgtt
     2401 ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct tgagctaagt
     2461 ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat gccgccaaaa
     2521 aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata atagcaccaa
     2581 gaatagctaa tgtaagccat ccagctacat catacatttg cccaactaga tttgataatc
     2641 cttcaccaac aattactcca ataggcccga ctacaactaa ggcaatacag cttgatacta
     2701 ataatactag cgtaggttgc aaaaaactct tagtaacagc tggtgttaat ttagcaatca
     2761 ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact gacgaaccat
     2821 aactagctgg tatcacaggt acaccaaata aactaagagg attccctgat tgcaccattt
     2881 gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta gatgttactt
     2941 ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat ggagcatccc
     3001 caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca agcattggta
     3061 aaataattac caagactttc agcatacctc cccctaacat tgctggaatg attggagtca
     3121 tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc ccttgaacaa
     3181 ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta gctacatcat
     3241 taccaagtat aatttgatat tgtccattct ttttcataat acctattaca cctggtatct
     3301 tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt aaacgtgtta
     3361 cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg attttttgta
     3421 ccttatcttt ataactcatg gtattctcct attctattaa tctaaatttt ttgttaagcg
     3481 acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat tgtactcagt
     3541 ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt tatttttcat
     3601 taatgctaac aagtcttcat catcatcgtc acaataagtt gtattttcaa ccaagcgatg
     3661 ggcaaataat tttatatgag ttatgaatct ataataatca atagaatctt ggttaaactc
     3721 agtacaatag aaatcttgaa tgattttctc aattcccata attatttcag tgattttata
     3781 cgactcttga aaattatttt ctaaattagc attaacaaaa tgtagcgcta tgaatgcagc
     3841 ttcgtcaatt ggaagttcaa tacctaactc tttttttatt atttgtaaag cccttttccc
     3901 aagctcaaat tcttctttat aatatttcga gatttcccag cgtaggggat tcgaaataat
     3961 aactccttct ttataacgtt ctatactcga agaaatatga tccgttagat ttatatagat
     4021 aatctcatca aaattattac ctaatgttat tttacctagg ttaattattt tttcggtgat
     4081 gtacaccaac tccaaaggaa cgttaataaa catctctgta aaacgggtca tattatctct
     4141 atttttgaga aaaaaacttt tctcaatatc aattggattt actttatctc cagtttttct
     4201 tccaaaagct attccccttc caaaaagaag aatatcgata tcttttttac tttgcgcaat
     4261 tacggcattg tggtttagta ttcgttttat gatcataaaa tttccctttt aaaataaaag
     4321 gaacctactt aaaaaacatc aagaaacttc ttctgatgtg attaaatagg ttcctgctca
     4381 cttgtattag tgataacatc cttttatttc aatttttaat ggtgacatga agcttaaata
     4441 attaataact ctgtaaccgt ttttatttta tgatatttca atctatttgt caagtactta
     4501 taaaaatttt tttattttgt gtgattcgaa tgtgataatg gcaacagtct cactaaagaa
     4561 atgaaaatca tacatagaaa tttttaaaaa ttttctctat cgtaaacctg ccactagttc
     4621 agaaactata ctagctgatt ccaaacgtaa tatggtcatc tcatctacct tccctaataa
     4681 tggcattgca ccataccaaa caatagtctt attcaccaaa agaataggcg ttactatttt
     4741 tgattgagta aaagacactt taattttctg gctcttcaac tggtctagcc atgctttatt
     4801 tgcaaccgtc tctggtatac atatctcaat ttgactaatc ctaaattctt ttagaaaatt
     4861 catcagtttt gtctggtgca cataaggtaa aataagcaga cattcctgtc tttcccctgc
     4921 taagtcctct ctcaacacct tctcatatct actatcaaca taaacgaatt gtttctcctc
     4981 accctcgatg acacgataat ccatctttcg ataagctact tgtcgtttct gaaacatctt
     5041 ttctaaataa ggaacatgaa tatccacata atcgaaaata cgcaccaaag acttatcctt
     5101 gtagtttcta tgaatccgac ctgcatactg aattaaatta tttttccaag aaaagggtgc
     5161 tgccaagata agcgtgtcca actgaggtaa gtcaaaacct tcgccaatgt attttccagt
     5221 agacaacaaa acaaaccctt tatctaactg ttctaacgtc tccagtaaac tcgttctttc
     5281 tcggactttg gtttttccgc taataatgta acagtcatca acctctttct ctttcaataa
     5341 cttttcaaag acatctatct gttgaattcg attaactaaa accaagatat tccgtccttc
     5401 tgccacttgg gctagaatat ccttgagaat caactgattc ctcgctgagt ctgtagcaat
     5461 ccaatcactg agctgtataa aattacttgc tttggtcttt tcaatctcca aatgaccaaa
     5521 agaagtgaat cttaattgca attgccgttt aaaatccgtt tccctcttat cagcagtatg
     5581 gagtatctca ccaattctct gaaaaacaat aggctcatga ccattcttac gctcaggcgt
     5641 agccgtcaaa ccgtaaagat acttccctct aaactgagca acaacttttt caaacatcaa
     5701 ggcagagaca tgatgacact catccacaat catcatctca tactcatcca aaagactttg
     5761 actattttcc aacttaaata gagattgaat cataacgaca tcaaccagtt tactcagcca
     5821 tttcttagtc ccaccgtact gtccaacata gccgattacc ttttcacgac ctgatgccgt
     5881 ataacggata gcctcctcct cttcgaaagt caaaaagcag tttaagcgat ctagccattg
     5941 gtctaagagt tgcttattat ggactagaat aattgttttt gttttccgtt cagagataag
     6001 agcagcacct aaaacggtct tcccaaaacc agtctccgca tgaagtaaac cattttcttt
     6061 agaagtcata tctgacaggg ctaactcttg ctcaaaagtg agttctccct taaattccac
     6121 gctaatagac ctttgtacct ttctcctatc ttccacagat acctgcttaa atttatcttg
     6181 caatggatat aacaagcctc ttggcagcca taaataataa tcggattctc caaataaata
     6241 cattctctca ggaatttgat aggttggctg tcgcatagcc tgctttaaat aaaattcggg
     6301 attagaaaat gaagccatat ttttcaagaa aaacagtgtc ttgggtgtca cagacgattt
     6361 ttcaagttgg atcatattgg ataagacgat cttcaactcc ttgtccaatt cttgcttgcc
     6421 taactcttct tggattaaca gtgccacttt agcagttgaa accctctgaa tttcttgtag
     6481 atacctccat tggtcttcat aaggctgaaa ctgttcatcc acaaagaccg ttcgcccttg
     6541 atggtaagct tctccttgaa aaggcaaggc aatcaaattt ccaaatcccc cccttaggaa
     6601 ggacatcctg atttggaaac atgcgatcaa aagaatcaaa ggacagttgc atactttcct
     6661 gcattgccag ttctatcagt ttctttccaa acaagcgagc ctctcgactc ggaatcgctt
     6721 cctcaaagaa gaaccaaata tggagtccgt gacccgaacg agaaatctct aaatgggctt
     6781 ccatctggcg ttccctggct attcttcgaa tggttaaacc agcttctttc caatctcctt
     6841 catcaaaatc cagtaccaaa aaatgacagc tatcatctaa gtgcatagga aagataccga
     6901 tagctgtctc cccacgaaaa tgagatttca aaacggagtc cgtcaatgtc tggaaactcc
     6961 gtttttcaag tggcaactgc ttccaaccat aatcatagga aggaaaatac tgaattttcc
     7021 cttgatcatt gataaaactc ttagcataaa catcataacg gccagcaaac acggaggtaa
     7081 acaattgtaa tttttcttgc gtcgtcaagt gactactttg aagttggaac atctcctcga
     7141 accgagagcg ttccatcaca aactgactct tgtctttaag acgtttacac aagaaaaact
     7201 cactatcccc attaaaagaa gaaaagacat caagtacttc taccacaatt ccatccaaag
     7261 acacaaaaat agccataaca atcacctcct tgattcctat aggctgatta taacaagaat
     7321 ggctgaaatt gtacacgaaa ataaaatccg aatagcactc attttgtatg cgactaatag
     7381 tccatctcgc tccggaatgt acgaagtaaa tagagtttaa acgagcagtc tataaaattc
     7441 aaaaaacgca tcata
//
LOCUS       DAVBNZ010000080         7400 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000080 DAVBNZ010000000
VERSION     DAVBNZ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.081"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ860_001966"
     CDS             226..6657
                     /locus_tag="VQ860_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET3120340.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKGLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6953..7299)
                     /locus_tag="VQ860_001967"
                     /pseudo
     CDS             complement(6953..7299)
                     /locus_tag="VQ860_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2890 a          992 c         1428 g         2090 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttatataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taactacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaagcatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa cataaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca attattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagggactat caaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccatttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttagggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgacaaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagacc taaagaaact cattaaaaag
     4441 aaatataagg aagaagacga ctttgtaact ggtggaaaaa gaacagtaga acttgattat
     4501 aaatatgacg ataaaggaaa tataactgcc tatgaagatg aaagtgctct agaatatgaa
     4561 actgaaaaat ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaataact ataaatttat agaaatcaaa gcgactaagt atgactcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa aattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccgtatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga cctttcaaaa aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatatactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagat
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa tagccattta taactcaatt atttagttta ctttacttta ctagtgatac
     6781 tatttggagt tattaatgga cttagtttat ataactaatg aattgattga aagggttagt
     6841 attgacaata ttggtcatat tgactagaaa atagagtcta tcaaaattta aaggctaata
     6901 gaggtgatga gacaatttcg gctctttgtc aactgtagtg ggttgaagtc agctaagctc
     6961 gagaaaggac aaattttgtc ctttcttttt tgatattcag agcgatgaaa atccgttttt
     7021 tgaagttttc aaagtttcga aaaccaaagg cattgcgctt gataagtttg atgagattat
     7081 tggtcgcttc cagtttggca ttagaatagt gtagttgaag ggcattgaca atcttctctt
     7141 tatctttgag gaaggtttta gaggatgaac ttgattcaga ttgtcctcaa tgagtccgaa
     7201 aaatttgtca ggctccttat tctgaaagtg aaaaagcaag agttgataga gattatagtg
     7261 gtgtttcaag tcttctgaat agctcaaaag tttatctata gtagattgaa actagaatag
     7321 tacacctctg cttctaaaac attgttagaa atcgatttga ctgtcctgaa tgatttgtcc
     7381 tgttattatt tcattttact
//
LOCUS       DAVBNZ010000081         7292 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000081 DAVBNZ010000000
VERSION     DAVBNZ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.082"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(112..387)
                     /locus_tag="VQ860_001968"
     CDS             complement(112..387)
                     /locus_tag="VQ860_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET3120341.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="VQ860_001969"
     CDS             complement(494..1333)
                     /locus_tag="VQ860_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3120342.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="VQ860_001970"
     CDS             1475..2323
                     /locus_tag="VQ860_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3120343.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="VQ860_001971"
     CDS             complement(2416..3333)
                     /locus_tag="VQ860_001971"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET3120344.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRIIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3770..3975
                     /locus_tag="VQ860_001972"
                     /pseudo
     CDS             3770..3975
                     /locus_tag="VQ860_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VQ860_001973"
     CDS             complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VQ860_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET3120345.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4596..4940)
                     /locus_tag="VQ860_001974"
     CDS             complement(4596..4940)
                     /locus_tag="VQ860_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET3120346.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VQ860_001975"
     CDS             complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VQ860_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET3120347.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5306..5393)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5488..6087)
                     /locus_tag="VQ860_001976"
     CDS             complement(5488..6087)
                     /locus_tag="VQ860_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET3120348.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLF
                     SSFVLGVVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6557..6856
                     /locus_tag="VQ860_001977"
     CDS             6557..6856
                     /locus_tag="VQ860_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET3120349.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7075..>7292
                     /locus_tag="VQ860_001978"
     CDS             7075..>7292
                     /locus_tag="VQ860_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3120350.1"
                     /translation="MGQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTR"
BASE COUNT         2335 a         1473 c         1193 g         2291 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgac
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggtat taccctcatc acattttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaaaat
     1681 ctttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccggctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggtgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatt ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattat acgaccacga gcattaccat gaaccaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatccgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggtaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgtt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccgaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc
     3721 actttccctg atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt
     3781 ccaacaactc ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 accattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaactg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg atatcaaaac aaaaaaacag gctctccgaa
     4201 aactcggaaa gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc
     4261 gggataaaag gttcaatgga cctttttatt tagcgattgg gtaaacagaa acttgttttt
     4321 tatcgcgtcc tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt
     4381 ctccaccacg accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga
     4441 ttgatccacc tgttacagtt tgtccgtcag ctgctttagc tccaagacgt tttgcttgtg
     4501 aatcacgtcc gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt
     4561 taagagtcat ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt
     4621 tggacgaact cagaatagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag
     4681 aataactggg tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga
     4741 tagccacctt catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata
     4801 gaattgataa agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat
     4861 tcgccactct cggcgtgtcc agtaatttcc gcacccctca gctcgccatc ttcggctctc
     4921 tcaaagactg cttgtatcat gtgttctcct taaaattaag cgttaattgc gttgatgaca
     4981 acttttgtat atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac
     5041 ttgtaagtaa caactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct
     5101 ccagcaacaa gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta
     5161 aaagtaactt cttgaccagc ttcaacgttc aatttttcaa tgtaaactgc ttgaccaact
     5221 tcaactttaa cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc
     5281 ctatgatttt tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacaa
     5341 accacttaaa cttgaataat caagcaacga tgttcgtgcg gttgcacagg atcgtgcata
     5401 gtcaactctt caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatca
     5461 agctttttct tttacttttt tctgccacta ggcaaaaagc atactgagat aaaaaatgct
     5521 catcataata ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga
     5581 aaagacaacg ccaaggacaa aactactaaa caggctaaca aatatgaacc cttcacgcaa
     5641 aaaaggagtg tgcttagttc ggaaataatc tccaaaagct agcattgttc gtttgatatt
     5701 ccctgtcata aaggcattat tgtaggcaat acccgaaacc tcaccaaaag cagttgtcac
     5761 cagtcccata cagaaggcca agggctgcac tagatagata ttatctacag tttgtggcac
     5821 aaaaccaata attattgata ggattgctaa aggaatcaag gacagaatag gttttttcac
     5881 aattctcaat ttttccttat aaatcgttaa taaaaagact cccattataa acgttattaa
     5941 ggttaaaagc ttatccctaa catccgaaac attattttgt attagctcta ccgaaagaaa
     6001 gacaacattt ccagcttgtc cagctacaag ggtattccct cgaacaataa aagtgtaagc
     6061 atccacatat ccagcacaaa atgtcaaaaa agtgctaacc ttttagactg acgtgatatt
     6121 tttcttatag gtaataacct cattttccct cccattgtat tttctcttag aaatattgta
     6181 ccatttcttt ctaaaaaatc gtagactacc atttagattt tactattagc ataaaaataa
     6241 taatagacaa ctatttatcc aaaaatagat agaggtaaca tgtttgcaaa caaagcatac
     6301 gaacctttag taaaatcatt tccatgaaac tagaatagag cccctcttag caaaaatcat
     6361 tattttaatt tatttctaat cactccttga cataaataac tctcaccaat aaaagactat
     6421 gtcttaaaaa aatggtataa taaaatcaat acctgggctt gatggctatg ctactaataa
     6481 caattaggag agaaaatcag gcacttgtta acaacaagga ttatcccctt gagatgaaag
     6541 gaactttaga aatcttatga tgaacatgca aaacatgatg cgtcaagcac aaaaacttca
     6601 aaaacaaatg gaacaaagcc aagctgaact tgctgctatg caatttgttg gcaaatctgc
     6661 tcaagatctt gtccaagcga ccttaactgg cgataagaaa gttgtcagca ttgatttcaa
     6721 tccagctgtc gttgacccag aggaccttga gactctttct gatatgaccg ttcaagccat
     6781 caactctgct cttgaacaaa tcgatgaaac tactaagaaa aaactgggtg ctttcgctgg
     6841 gaaattgcca ttctaaaaac aaggagctag aacaatactt gtcgataaca aaggctaaga
     6901 aaggtgcaaa aattataaaa aacgcatagt atcaagcaac ctaaaacttt gggctctata
     6961 atatttgtag tgggtaaatc cactatagat attatggagc ctattttatt gtagaaaaaa
     7021 atcccataag atctataatg aaaagcgacc aaacaactca ttagaaagat tcatatggga
     7081 caattacatt ttatcacaaa attactagac attaaagacc ctaatatcca gattttagac
     7141 atcatcaata aggatacaca caaggaaatc atcgccaaac tggactacga cgccccatct
     7201 tgccctgagt gcggaagtca aatgaagaaa tatgactttc aaaaaccgtc taagattcct
     7261 taccttgaga caactggtat gcctactaga at
//
LOCUS       DAVBNZ010000082         6943 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000082 DAVBNZ010000000
VERSION     DAVBNZ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6943
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.083"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(57..287)
                     /locus_tag="VQ860_001979"
     CDS             complement(57..287)
                     /locus_tag="VQ860_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120351.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(305..946)
                     /locus_tag="VQ860_001980"
     CDS             complement(305..946)
                     /locus_tag="VQ860_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3120352.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(958..1692)
                     /locus_tag="VQ860_001981"
     CDS             complement(958..1692)
                     /locus_tag="VQ860_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET3120353.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1695..1892)
                     /locus_tag="VQ860_001982"
     CDS             complement(1695..1892)
                     /locus_tag="VQ860_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120354.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(1892..2098)
                     /locus_tag="VQ860_001983"
     CDS             complement(1892..2098)
                     /locus_tag="VQ860_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3120355.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2108..2422)
                     /locus_tag="VQ860_001984"
     CDS             complement(2108..2422)
                     /locus_tag="VQ860_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120356.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(2647..2727)
                     /locus_tag="VQ860_001985"
                     /pseudo
     CDS             complement(2647..2727)
                     /locus_tag="VQ860_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(2718..4007)
                     /locus_tag="VQ860_001986"
     CDS             complement(2718..4007)
                     /locus_tag="VQ860_001986"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET3120357.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRAYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVSQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4104..5333)
                     /locus_tag="VQ860_001987"
     CDS             complement(4104..5333)
                     /locus_tag="VQ860_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET3120358.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SILCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFFDNS"
     gene            complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ860_001988"
     CDS             complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ860_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HET3120359.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6501..6842
                     /locus_tag="VQ860_001989"
     CDS             6501..6842
                     /locus_tag="VQ860_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3120360.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         2249 a         1442 c         1278 g         1974 t
ORIGIN      
        1 ctctttgatt ttcattgagt ataatacaaa aatccgatga acttcaccgg actcttttat
       61 tttgaatttt tgcctgcttt acgcttttca gcgatttcgg ctgcctttcg aggcaagaca
      121 atttccgtta tgtaagccgt cccaaaacgc agtacacctg caataggagc aaagacaact
      181 gctagatagt tatagaagaa atcgcctttg aaggcataag ctagcgctcc aatgatgaaa
      241 aatagaacga ctgcctgaat cactgctact aaaattactc gtttcatgtg acctcctgac
      301 tctattatag catgagaatc atcaaaaagc cgactaaatt attcaaagcg tgaagagaaa
      361 tactgtagac cagacctttt ctgctaatgt aagccaaacc caaactaaaa ccaaggctaa
      421 aatagacaaa aaattgttgc acatcacctg gaaaatgaat caaggcaaat agaagactag
      481 ataccagaag aaaaatcagg gttcgtttac tattgtcctg cttaggaaag agatagcgtg
      541 ctaacatccc tctaaaaaca atctcttccg tcaaaggagc aaaaataacc acagcaaaga
      601 atgagaaaag tggttgagac aaggtcaagt ctgtcgctat ttgttgattt actgaaggat
      661 catctggcaa gaagaattga acgaccagag ataagaacca aaccaagaca ggaagccaaa
      721 taaatcgatt aaagccgctc ttctcaatat gaacaggagc cttctgatac catttgtaaa
      781 tgccgtacac atatactcca gccaaggcca catagagtag agtaacagca tagggtgaag
      841 cgcctaaagc aagcgacgca gtcgcgagcc cctgaataaa gccatagata aataaaaagg
      901 atagaagggc tagaagaatc cagccaaggt ttttaagtaa tttcatagat aactccttta
      961 tttgaaataa cgttttacca taggtaactg catcacattg atataaacat ggatggctcc
     1021 tacaagcaag aaagctagta actgaatctc tcctgtcaag aaagaaatga taataagaaa
     1081 aatatataag gctggtaaga catattggtg taattggaat aaaattcgaa aactctgttc
     1141 caaattagcc tgacgctccc cttcatcata agaatttata tagttcaaga catcctttgg
     1201 tgtagcgaaa aattccaaat caaactgacg aacaatcgca atggttttaa aaagagattt
     1261 ttgagcgact aagaatacca caaagagtaa gaaagaaagg aaaaatgttt gagggtttgt
     1321 atgcaatata atcacctcac ttaatgaaat aaaaatagcc aatggaatcg ctacacctgt
     1381 aatattaaaa gcaatggttc caaactcaag attccgatac atttgcacat aataggtttc
     1441 attcagatcg tcatccattt cctcttgata caaggaatga aattttctgc ttttctttaa
     1501 gaaattgaaa gtcaaaaaca tactaatgaa acctatcagt aaacaaatag ctgatatcca
     1561 tggcatcaag gcttttacat ctaaaataat ttcgtgggat tcgacacgtg ccttaaacat
     1621 ccctacaaac atgcccaaga acccccccaa gacaatagac atcaaaaata acaatctacg
     1681 tttctttttc atattcattc tcctttttca cttgctagat ttttggattt cttttcaatc
     1741 cattcagtta ctgggatgag agcaaagtag acccaaacaa attggtcgct ttgataggga
     1801 ttaaaccagc ttaggtccat cccaatcagt agaaatacgc tgactaataa agctatgacc
     1861 actacataat aaatcacttt atacttgttc atcactcgtc ctcctccaaa cgaaataccg
     1921 attcgactgt ttcgttgaaa atttgagata ttttcagggc aatgataatg gatggggtgt
     1981 actcatcccg ttctagtagg ctaatggtct gtctggaaac ccctgccagt ttggctaggt
     2041 cggtttgatt gagaccatcg cgagctcgaa gctcttttag acgatttttt agttgcacgt
     2101 tacacaccta ctctccgtca aattcaacgg tttggatatc ttcaatacgt tgcaacttga
     2161 atttttcttt tcccgtatta tcaacactac gtagtttgac ccattcctca tcaacatcca
     2221 caacttccca gttatctggc ccaatataca ctcccgttat aattggttcc tttccaatca
     2281 tttcttgtaa taatctcgac atttctgcgt ttcctttctc ttttcgctca agttttttga
     2341 ttttattctc tagtttcttg atttttttag aattattaga ataaaagaaa atcataaata
     2401 gtataaatcc tagtacccac attataactc ctttctgctt cctatttctt aacttgaatt
     2461 cattgtaaca tatctttttc tttttgacaa ttatagttgt caaaaagttt atgatttttg
     2521 tcattttgca aaagaaaaag gtcaggagta agttcctgac cactttatct atcattaata
     2581 ctcttctaaa atctcttcaa accacgtcag cttcaccttg ccgtaggcat ggttactgac
     2641 ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag caacctgcgg ctagcttcct
     2701 agtttgctct ttgattttca ttgagtataa aatcctagtt tttcaaagat ttctgagaag
     2761 ttttggctga ttgtctcaag tgacacttgc acttcttctc gggtttggtt gttcttgact
     2821 gtcacttgtc tgctttcgac ttcgctctct cctagggtga tgagggtctt agccgcaaag
     2881 acatcggctg acttgaactg agctttgagc ttacggttga ggtaatcacg ctctgctttg
     2941 aaaccttgtt ggcgaagagc ttggactagt tctagggctt tgacatttgc tccatcaccc
     3001 aagactgcga tatagacatc tagggcattt tcgataggga gggccacgcc ttgtttttca
     3061 aggatgagaa gcaggcgctc tacaccaagc ccaaaaccaa atccagcagt ttcagggcct
     3121 ccaaagtaag caaccaaacc atcgtagcga ccacccgcac agactgtcaa gtcattgccc
     3181 tcaatctctg tgataaactc gaaaatggtg tggttgtagt agtccagacc acgcaccata
     3241 ttggtatcga tgatgtaatc tactccaaga ttttccaaca tctgactcac agcatcaaaa
     3301 tgagtttggc tttcttcatc aagaaagtcc aagatagacg gcgcattctc tactgccacc
     3361 ttgtcttctt tttccttaga gtccaagaca cgaagaggat tttcctccaa gcgacgttgg
     3421 ctatccttag acaaggtctc cttgagcggt gtcaaatagt caatcaaggc ttggcggtag
     3481 gctgcacggc tctcaggatt tccaagagtg ttgaggtgca atttgacacc ttgaataccg
     3541 atttccttca aaaaatgggc tgccataacg attgtttcca catcggtagc tggattgcta
     3601 gaaccaaaac actcaacacc aatctggtgg aattggcgca agcgccctgc ctgtggacgc
     3661 tcataacgga acataggtcc catgtagtag aacttgcttg gcttttgcac ttctggagcg
     3721 aagagtttat tttccacata ggcacggaca acgggcgcag ttccttctgg acggagggta
     3781 atatggcggt cacccttgtc atagaaatcg tacatttcct tggttacaat atctgttgta
     3841 tctccgacag agcggctgat aacctcgtaa tgctcgaaaa taggcgtacg cacttctgcg
     3901 tagttgtagc gcttgaaaat ttcacgggca aagccctcaa cgtactgcca cttagcagac
     3961 tcagcaggta aaatatcctg cgttcctttt ggtttttgta atttcatagg gaatcctctt
     4021 taaacttaat agtcttattt taccataaat agagggatta aaacagtaag aaaaaaatta
     4081 ggatttagat atcatttttg agattaagaa ttgtcaaaaa aaatagctag caaggaaaga
     4141 ccaacaaata gcatccaagt caactgtata ttccatacgg ctactagtga aaaacaagct
     4201 gttcccacag gtatggataa ggtaaacaat agacctaaaa aattactagt acgagctaga
     4261 acctctggag ctagattttt catgagcatg gcactaatct ttggttgaac tttaccagac
     4321 acatacagag taaagaagag aaatagcaaa ccaagcacga cttgattgaa taaattagcc
     4381 aaaccaacta gactaagccc tacggtcgcc cacatcatca atctaggcaa ggactgcttc
     4441 ccaaaataat cattgcccgt aaggctactg atgatgactg ctactaaaac acagaattga
     4501 ttgataaata gtgcctctgt ataagaaaaa ttcaagagag aatggctcaa aaagaagata
     4561 ttataaattc cacccaaagc gccacccaag gaattaataa gcaagacagc aaagagcata
     4621 aaaccaaagt ttttctgtcc acttttaaga aaaacgagac gtaaatttcg gtaaattgtt
     4681 aggaactggt ctttgataga aagcttctca ttttttaagt tttcaccatc agcagatgac
     4741 attgacaggc tcaatttgct ttttcctaaa aagaggatag tggctgatac taggaaaaag
     4801 caggcattga ttcccgcaac gagagaaaaa ttgttgaccg atagagctaa gagccagact
     4861 ccgaaagctt gaccaccaat agctgaaata taggtgatga actgtgaaaa agaataagcc
     4921 tccatcagat catcttcagc tactttttcc ttaataagag gcatacgcag gccacctgca
     4981 aaatcactga tgatatcact aatgacattg atcaaacaca ggatagaaaa ggcaaagaga
     5041 ctagcttgct gaacaactag ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta
     5101 tagaccatcc atttgacctt gtccctcgtg taatctgccc gaatccctgc aaaaactgta
     5161 aagagggtcg gaagaatcat gacaatattc gccatagcaa cagcaaaaga tgcttgtgac
     5221 aaggtcgatg catagacgat aaagaccagg ttgaaaatcg aagcaccaaa agcattgaag
     5281 aagcgtgata aagtcaaaat tctataagct ggatttctaa acaatagttt catagataat
     5341 ctcccttctt gttcgaacct ctatatgaag tatgactata gtatagcact tagaaatttg
     5401 agagggagaa ctcttgaata tatgcaacaa ataaaatgag caaaaagaaa cgatagaact
     5461 tttgtaatga cctgagagag ggcaatagtt ctatcgcttc aaattttttc ttggtttgca
     5521 gatattcaac attcggtcgt atttctatag tattcggcag atttattaca gccaagcatc
     5581 tcaaaaatac ggacagcatc ctccatcttt ttctggcctt ccttgactct accttgcttg
     5641 ctatcaagga gaccttctgc ccacagataa acaattcgga aataggtctc attttccttg
     5701 tagaaatgct cttcgataac acgtttaaaa taataggcat tggtaaattc ttcacactca
     5761 atactagcta aaaagccgtt caatagtata gtatgaaaaa ggtttcgatt gccagacatt
     5821 tccattagaa aatcagattt acgtaccatt tctcgtacat atctagtaaa aagagaaaca
     5881 gataaaaatg gagaactgac tgaaaataaa ttgagttcat agattcccca gatctcggta
     5941 gaaaacaaat aatcatgaag gacttttcct tcctctgctg ttaagtctac cctttcatct
     6001 atgctcttca tataagactt gataataatg gcatttagaa tatgtttctg tttgttgtga
     6061 gaatgggcat gcttttgata ctccctgcga tataagtcct caagaggtgc tatattcttt
     6121 ggttccaaga catctgtaat ttcttttctc aactcagaat ctgtatcata ctggaaacct
     6181 ctcgccagaa agaggatctc ctccacactg gcagatatat tttccagagc aaatagaaac
     6241 ttttccaccg aaagctcact ctgacctgtt tcaaaacggg acaacataga cggcgaaaat
     6301 tgtcctccgg ttgcttgtct cagtgagata tttcttgact ctcgtaattg tctaaagact
     6361 tttccaatct gctccataga cttccccttg attccgtatt ttcttcattt tatcatattt
     6421 ttcagaaaat taatcaaaag cttgccaaat tgtcagaatt atgagaaaat agaggatatt
     6481 tatcacatgg agggactgct atgagagacg atatcaaaat caatgaccgt gctttggcct
     6541 tgcaagacca aattatcgaa aaactagaga aagtttttga tacagatgtg gaattggatg
     6601 tttacaatct aggtctgatt tatgaaatca atctggatga aacggggctc tgcaagattg
     6661 tcatgacctt caccgatact gcctgtgatt gcgccgaaag cctgcctatt gaaattgtgg
     6721 caggtctgaa acaaatcgag ggtatcaaag atatcaaggt tgaagttacc tggtcgcctg
     6781 cttggaaaat cacacgaatc agtcgctatg gccgtattgc ccttggacta ccacctcgtt
     6841 aagcaggcca atcactttta aagatgaaaa aagcaagccg aaaatggctt gctttttgat
     6901 actcaatgaa aatcaaaggg caaactagaa aactagccgc agg
//
LOCUS       DAVBNZ010000083         6793 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000083 DAVBNZ010000000
VERSION     DAVBNZ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6793
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.084"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..379
                     /locus_tag="VQ860_001990"
     CDS             <1..379
                     /locus_tag="VQ860_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS630-like element IS630-Spn1 family
                     transposase"
                     /protein_id="HET3120361.1"
                     /translation="RGKVSGRRYQRISLVAGLTNGELIAPMTYEETMTSDFFEAWFQN
                     FLLPTLTTPSVIIMDNVRFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKK
                     HLKKVLPSCNTFYEAFLSCSCFN"
     gene            440..1402
                     /locus_tag="VQ860_001991"
     CDS             440..1402
                     /locus_tag="VQ860_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3120362.1"
                     /translation="MNMSNITIDGQEIDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMFGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1580..2587
                     /gene="gap"
                     /locus_tag="VQ860_001992"
     CDS             1580..2587
                     /gene="gap"
                     /locus_tag="VQ860_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET3120363.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2654..3490)
                     /locus_tag="VQ860_001993"
     CDS             complement(2654..3490)
                     /locus_tag="VQ860_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3120364.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3616..5811
                     /locus_tag="VQ860_001994"
     CDS             3616..5811
                     /locus_tag="VQ860_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3120365.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVDLTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5864..6016
                     /gene="rpmG"
                     /locus_tag="VQ860_001995"
     CDS             5864..6016
                     /gene="rpmG"
                     /locus_tag="VQ860_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3120366.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6026..6202
                     /gene="secE"
                     /locus_tag="VQ860_001996"
     CDS             6026..6202
                     /gene="secE"
                     /locus_tag="VQ860_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET3120367.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6257..6793
                     /gene="nusG"
                     /locus_tag="VQ860_001997"
     CDS             6257..6793
                     /gene="nusG"
                     /locus_tag="VQ860_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET3120368.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2114 a         1190 c         1465 g         2024 t
ORIGIN      
        1 aagaggcaaa gtatctggaa gaagatatca gaggatttct ttggttgcag gtctaacaaa
       61 tggtgaatta atcgctccaa tgacttacga agagacgatg acgagcgact tttttgaagc
      121 ttggtttcag aattttctct taccaacatt aaccacacca tcggttatta ttatggataa
      181 tgtaagattc catagaatgg ggaagctaga acttttatgc gaagagtttg ggcataaact
      241 gttacctctt cctccctact cacctgagta caatcctatt gagaaaacat gggctcatat
      301 caaaaagcac ctcaaaaagg tattaccaag ttgcaatacc ttttacgagg cttttttatc
      361 ctgctcttgt ttcaattgac tatatatcac ggatacagtt gggaaagaag ctattaaata
      421 tttggagagt ccttttggga tgaacatgtc aaatattact atagatgggc aagaaataga
      481 tctgagtcaa acgatgcctt cttatgctca agtagtgagt ctttatgatg atacaagtat
      541 ctctgttagt agtaatgaga cggacaaagt gttggctgga tccctctata ctgatacaaa
      601 tgaacaggga ttaacgattc caagcagttt actaaaaaat tggaatgaac agacaggaaa
      661 aaatttgaca gctaatgatc ttattggcaa atcagtctca gccagcattg tagaaagtgc
      721 tgccgaaact agtaagattg ctcaatttca aacgaagatt gtacgtgtaa tcaatgatga
      781 agatgacatg gaggacagca acagtttcat gctgtctcat caaatggaaa cgattttgaa
      841 agaggctgga tttacgaaag ctgtatctta ttttatcttg gaactcaaag atccatcaca
      901 gacaaaagta gtaacagaag aattacagaa aaataagaag tatactgtgc tttctcaaca
      961 gagagttctt gatattgtga ttacctttat tcgtgttatt cagggattat tgattgtgct
     1021 ttcatcacaa gctattgtgg tagcagcggt tatgtttggt atcattattt acatcaatat
     1081 catgcaacgt tctaaggaaa taggtgtcat gaaggcagtt ggttatcaga atcgtgatgt
     1141 caaaggaatt tttatttacg aggctatctg gattgtaggc atcgccttgc tgctggcatt
     1201 tttggttgca caaggggtgg gaagtttggc gaatgcgatt gtaagtcact tttacccatc
     1261 catcactaag gtttttgaat taaatctttt atctgtttta ggaactctag ttttcgctct
     1321 attacttggt tatgtctcag cctacttccc ggcgcgtaag attagtaaaa tggatcctgt
     1381 agaaccgtta cgctatgaat agtaagggat tccttgattt acagtcttaa aaaagaaact
     1441 aacatagaaa aacaatggcc atacttgcaa ttcaactcaa atagttgtat aataggtttg
     1501 ttgaaaggtg atttgtagtg attcaagtta ctcttttcac aataaaaatt tcatgatttt
     1561 cataaggagg aaatcactaa tggtagttaa agttggtatt aacggtttcg gacgtatcgg
     1621 tcgtcttgct ttccgtcgta tccaaaacgt agaaggtgtt gaagttacac gcatcaacga
     1681 ccttacagat ccagttatgc ttgcacactt gttgaaatac gacacaactc aaggtcgttt
     1741 cgacggtact gttgaagtta aagaaggtgg atttgaagtt aacggtaaat tcgttaaagt
     1801 ttctgctgaa cgtgatccag agcaaatcga ctgggctact gacggtgtag aaatcgttct
     1861 tgaagctact ggtttctttg ctaagaaaga agcagctgaa aaacacctta aaggtggagc
     1921 taaaaaagtt gttatcactg ctcctggtgg aaacgacgtt aaaacagttg tattcaacac
     1981 taaccacgac gttcttgacg gtactgaaac agttatctca ggtgcttcat gtactacaaa
     2041 ctgcttggct ccaatggcta aagctcttca agataacttt ggtgttgttg aaggattgat
     2101 gactactatc cacgcttaca ctggtgacca aatgatcctt gacggaccac accgtggtgg
     2161 tgaccttcgc cgtgctcgcg ctggtgctgc aaacatcgtt cctaactcaa ctggtgctgc
     2221 taaagctatc ggtcttgtaa tcccagaatt gaacggtaaa cttgacggat ctgcacaacg
     2281 cgttccaact ccaactggat cagttactga attggtagca gttcttgaaa agaacgttac
     2341 tgttgatgaa gtgaacgcag ctatgaaagc agcttcaaac gaatcatacg gttacacaga
     2401 agatccaatc gtatcttcag atatcgtagg tatgtcttac ggttcattgt ttgacgcaac
     2461 tcaaactaaa gttcttgacg ttgacggtaa acaattggtt aaagttgtat catggtacga
     2521 caacgaaatg tcatacactg cacaacttgt tcgtactctt gaatacttcg caaaaattgc
     2581 taaataattc ttgagttgat agaaagcaag gctttgtggt cttgcttttt atatagaaaa
     2641 atggatgaca cgatcatcca ttctttttta attctttttc aaatgtattt gaaagggtag
     2701 tgaaagttag cctctctaaa gtaagtgggt gggtaaagga aagtcggaag gcatgaagca
     2761 taagccggct tgtctttgat ttactattat agagagggtc tcccaggata ggaagattat
     2821 gatgcaaaag gtgcacacga atctgatggg ttcgccctgt ctttagcttg caatgagcca
     2881 aggaagtctt gtttgagaat tgctttaatc tgcttacatg cgtttcagca tattgcccat
     2941 tttttgcatc aactattctt tttctacgat catggcgatc acgtccaatt ttgtctctga
     3001 aaacaagttc ttttctgttg atatttccat caactagagc ccaatattct ctagaaatct
     3061 cttttttctc caataagcga ttgagaatgg gcaggataaa aggatttttg gcaaagagaa
     3121 ctaagccact ggtttccatg tccagacgat gaacgacata gcaggtttgg ccaacatagg
     3181 tactgacatg gttaagaagg gcaatttcgt ttggttgatt accatgcgtt ttcatcccct
     3241 ctggtttgtt tacaataatc aagtgttgat cttgataaac ttcctgcact aagtctgggt
     3301 tgccccaagg gatcgtcttt tggggataat cttcctcgtc aaaagtcaac tggcaaacat
     3361 ctccaggatt tacgatttcg ttccagtgga cttcttcttg atttatcaaa atatgtttct
     3421 tgattctcaa aaaatgacgg atttttctag ggatgaggag ttgttcctca agtaattgct
     3481 ttaccgtcat ttgaggtata gaggcgggta atgtaaatgt gaattgcata cagatattgt
     3541 aacaaaaaaa gccctatttg gataggaaat agctaaattc ttgtcttcct atgatgaaga
     3601 tgataaaata aacgcatgaa attagataaa ttatttgaga aatttctttc tctttttaaa
     3661 aaagaaacaa gtgaactaga ggactctgat tctactatct tacgtcgctc tcgtagtgat
     3721 cgaaaaaaat tagcccaagt aggtccgatt cgaaaattct ggcgtcgtta tcatctaaca
     3781 aagattatcc ttatactagg tttgagtgca ggcttgctag ttggaatcta tttgtttgct
     3841 gtagccaagt cgaccaatgt caatgatttg caaaatgcct tgaaaactcg gactcttatt
     3901 tttgaccgtg aagaaaaaga ggctggtgcc ttgtctggtc aaaagggaac ctatgttgat
     3961 ctgactgata tcagtaaaaa cttgcagaat gctgttattg cgacagaaga ccgttctttc
     4021 tataaaaatg acgggattaa ctatggccgt ttcttcttgg ctattgtcac tgctggacgt
     4081 tcaggtggtg gctctaccat tacccaacag ctggctaaaa acgcctattt atcacaggat
     4141 caaactgttg agagaaaagc gaaagaattt ttccttgcct tagaattaag caaaaaatat
     4201 agtaaggagc aaattctaac catgtacctt aacaacgctt attttggaaa tggtgtgtgg
     4261 ggtgtagaag atgcgagtaa gaaatacttt ggagtttctg catcagaagt gagtctggat
     4321 caagctgcga ctctggcagg gatgctcaag gggccggaac tgtataatcc cttgaattcc
     4381 gtagaagatt ctactaatcg gcgcgatact gtcttgcaga atatggttgc agcaggatat
     4441 attgataaaa accaagaaac cgaagctgct gaagttgata tgacttcgca attgcacgat
     4501 aagtatgaag gaaaaatctc agattaccgt tacccctctt attttgatgc ggtggttaat
     4561 gaagctgttt ccaagtataa tctaacagag gaagagattg tcaataatgg ctaccgcatt
     4621 tacacagagc tggaccaaaa ctaccaagca aatatgcaga ttgtttatga aaacacatcg
     4681 ctatttccga gggcagagga tggaacgttt gctcaatcag gaagtgtagc tctcgaaccg
     4741 aaaacagggg gagttcgtgg agttgtcggt caagttgctg acaatgataa aactggattc
     4801 cggaatttca actatgcaac ccaatcaaag cgtagtcctg gttctacaat taagccttta
     4861 gttgtttata cgccagcagt tgaagcaggc tgggctttga ataagcagtt ggataaccat
     4921 accatgcagt atgacagcta taaggttgat aactatgcag ggatcaaaac gagtcgagaa
     4981 gttcctatgt atcaagcctt ggcagaatcg cttaatctac ctgctgttgc cactgttaat
     5041 gatttgggtg tcgacaaggc ttttgaggca ggcgaaaaat tcggactcaa catggaaaag
     5101 gtcgaccgtg ttcttggtgt cgccttggga agcggtgttg aaaccaaccc tcttcaaatg
     5161 gctcaagcat acgctgcctt tgcaaatgaa ggtttaatgc ctgaagctca ttttattagt
     5221 agaattgaaa atgctagtgg acaagttatt gcgaatcata aaaattcaca aaaacgggtg
     5281 attgataagt ctgtagctga caagatgacc agtatgatgt tggggacttt caccaacggt
     5341 accggtatta gttcatcgcc tgcagactat gtcatggcag ggaaaactgg aacaactgaa
     5401 gcagttttca atccggagta cacaagtgac cagtgggtaa ttggttatac tccggatgta
     5461 gtgattagcc actggcttgg ctttccgacc actgatgaaa atcactatct agctggctct
     5521 acttcaaacg gtgcagctca tgtctttaga aacattgcca ataccatttt accttatacg
     5581 ccaggaagta cctttacggt tgaaaatgct tataagcaaa atggaattgc accagccaat
     5641 acaaaaagac aagtacaaac caatgataat agccagacag atgataattt gtctgatatt
     5701 cgagggcgtg cgcaaagtct agtagatgag gctagccggg ctatctcaga tgcgaagatt
     5761 aaggaaaagg ctcaaacaat atgggattcg atagtcaatc tatttcgcta agatgcttgt
     5821 caaagcctag ctttcttgtt ataatggata agatggaggc gttatggcac taaaaaaagc
     5881 aagcctagct tgtgcggttt gtggttcgag aaactattca atcaagatca gcggaaaccc
     5941 caagcctaca cgactagaag taaataaatt ttgtaagcat tgtggcaagt acactacaca
     6001 cagagaaacg agataggaga gagcgatgcg ttttattgga gatattttta gacttcttaa
     6061 agacacaaca tggccaactc gcaaggaaag ctggagagat tttcgttcta tcatggaata
     6121 cacagctttc tttgtagtaa ttatttacat ttttgaccag ttgattgttt caggtttgat
     6181 tcgatttatt aacatttttt agaagattag tggagttaat tacactagaa atcttctatt
     6241 tatgaaagga aatatcatgg atagttttga taaaggatgg tttgttttac aaacttattc
     6301 tggttatgaa aataaggtga aagaaaatct attacaacgt gcacaaacct acaatatgtt
     6361 ggataatatt ctacgcgttg aaattccaac acaaacagtg caagttgaaa aaaatggaaa
     6421 gagaaaagaa gtagaagaaa atcgctttcc aggttatgtt cttgtagaaa tggtcatgac
     6481 agatgaagct tggtttgttg ttcgaaacac accaaatgtt acaggatttg tcggatcaca
     6541 cgggaacaga tcaaaaccaa ctccattatt ggaacaagaa attcgtgaca ttttggtatc
     6601 tatgggacaa actgttcaag aatttgattt cgatgttgag attggtcaaa ctgtacgtat
     6661 tattgatggt gcttttgcag actacactgg taagattaca gaaattgata ataacaaagt
     6721 gaaaatgatt atctctatgt ttggtaatga cacagttgca gaagtaaacc taaaccaaat
     6781 cgcagaatta taa
//
LOCUS       DAVBNZ010000084         6744 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000084 DAVBNZ010000000
VERSION     DAVBNZ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6744
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.085"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(58..384)
                     /locus_tag="VQ860_001998"
     CDS             complement(58..384)
                     /locus_tag="VQ860_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3120369.1"
                     /translation="MVEYISRKYFLTEEEFQAEKICNQSLVELFQKKYSWHSLNDFGS
                     STYDKNYASIFYEYWRSFLTVDKLVENLGSVQAVLDSYHLWANTEKTFPLLDWFVQQK
                     LIEKEI"
     gene            complement(351..635)
                     /locus_tag="VQ860_001999"
     CDS             complement(351..635)
                     /locus_tag="VQ860_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3120370.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMTLISGSKRGWLNILVASIS"
     gene            complement(908..1750)
                     /locus_tag="VQ860_002000"
     CDS             complement(908..1750)
                     /locus_tag="VQ860_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET3120371.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALVWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(1864..3255)
                     /locus_tag="VQ860_002001"
     CDS             complement(1864..3255)
                     /locus_tag="VQ860_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET3120372.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(3490..3867)
                     /locus_tag="VQ860_002002"
     CDS             complement(3490..3867)
                     /locus_tag="VQ860_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3120373.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            4082..5059
                     /locus_tag="VQ860_002003"
     CDS             4082..5059
                     /locus_tag="VQ860_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3120374.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLTDKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYKTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            5056..6138
                     /locus_tag="VQ860_002004"
     CDS             5056..6138
                     /locus_tag="VQ860_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3120375.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRIGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(6202..6744)
                     /locus_tag="VQ860_002005"
                     /pseudo
     CDS             complement(6202..6744)
                     /locus_tag="VQ860_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         2037 a         1482 c         1136 g         2089 t
ORIGIN      
        1 tctgccactg atgcagtgaa atgtcaattt cttagacatt gtttactcct ttagttttta
       61 tatttctttt tcaattaatt tctgctgaac aaaccaatct aacaagggaa aagttttttc
      121 tgtatttgcc cataaatgat aagaatctaa gaccgcttgt acactaccta aattttctac
      181 caacttatct actgtcaaaa agctgcgcca gtattcataa aaaatacttg catagttctt
      241 atcataagtc gaagaaccaa aatcattcaa tgaatgccaa ctatacttct tctgaaaaag
      301 ttctacgaga gattgattac aaattttttc cgcttgaaat tcctcttctg tcaagaaata
      361 cttgcgacta atatattcaa ccatcccctc ttcgaaccag atataagagt cataaccatt
      421 cgtctattat ttgtataggc tggaacagcg ctttccctaa taatctgtgt agcagcatta
      481 aaatctgacc aaataacggc ttgcggtaaa tcacagactg caagttcatt ctttaaaaaa
      541 gattgataat ctttcaactt ttcagtattt cttactacaa aatcacgaaa tgtagctagt
      601 tgactatcgt cttttacaag ataaaggttg tccacggctc tcctttcttt cacacaatag
      661 actgaataag caaaagaacc acatctgaca atcctaggtt gatttaacct aggggcgtca
      721 gaaacgcggt tccaccctaa tttattactt cattgttttt gaaaatacta cagaaagcgc
      781 cagctcatta ttttgcccta cttggctccc actgtcccaa gctcgcttga agaacgccat
      841 aagactttct ttcctgctga ctattatatc aaaaattaga ataatgtaca attcttttta
      901 tgattttcta gaaatccaca tcatcaactc gtggagcacc cgattgaaca gcaatcgttt
      961 ttaaggtttc tctctcctca tgactcagtt caattccaaa gcaatcaaga ttagcttgaa
     1021 tacgagaggt tgtgacagat tttggaagtg gtaaaaatcc ttctgccaag ctccagacca
     1081 aggctatctg agcaatcgat tttccgtgat ttgctgcgat ttcttgcact tgcttgctat
     1141 caaatagttc tccctgacca aaaggccccc aagcttccaa taaaattccc ttttcacgac
     1201 agtaagctac gacttgttct tgatacacac ctggcgccaa gcgaacttga ttgaccgcag
     1261 gaacgatagt tgcagtttca agcaaggcat ccaaatgatg gggaagaaaa ttgctaacgc
     1321 cgatagcacg gattttccct tcttgataga ggtcttccat cgctctccaa acttccgcat
     1381 tgcgagtttt ccatgcgtca ttttctctga gcggttttgg gttcggccaa tgaatcaaat
     1441 acaaatccaa ataatccaag cccagttttt ctatagattt ttccaaagct tgacgagttt
     1501 gctcataggt ttgctgacta ttccaaagct tggtagttac gaacatttct tcacgtggaa
     1561 ctccgctatc tttgattgct tgaccaacac tttcttcatt ctgataaatc gccgccgtat
     1621 caatatgacg ataaccagcc ttcaaggctt ctaacactgc acgataggct tcttctccat
     1681 ccttagcctt aaaagttcca aatcccaata ctggaatttc tactccatta tttaattgat
     1741 aggtattcat atgcttctcc ttctatttta ttcatcaatt atagcataaa acatttttta
     1801 agtagtacta tattctgtaa aaaataagtc tgtcaaatat ctaacagacc tattttttct
     1861 tgcttattca tcacgactat agtacagctc atgagctttt aggcgagtat tgagcatctc
     1921 tggtatggtc acaaaggtat aaccttgatt tttcaaatac tcaatgaccc ttggcaaggc
     1981 attgactgtc ggactgtgaa tatcatgcat caaaacgata gagccgttag ctacttgatg
     2041 ctgaatttct gtcaaaatag atgcttcatt tttactcttc cagtccagac tatccacatc
     2101 ccacatgata aagctcaaat ccaagctatt gcgaatatca tctgtaatag caccataagg
     2161 tggacgcatg agtttagaac tagaacccag cactttagtt agcacatcct cagtatcagt
     2221 aatctgcttt ttagcttcat caagagagag ttgcgagaga atcggatggc tccaactatg
     2281 gtttccaaca acatgacctt cagattttat cctcttcacc aagtcctcat tcccagaaac
     2341 atttttccca agcacaaaga aagtcgcttt aatatcatat ttagctaggg tctctaatac
     2401 ctgcggggtc gttgctggat ttggaccatc atcaaaggtt agagcgacaa ctttttgatg
     2461 tttcttatca aagtaagatt ggtacaaggc cgcatctttt tcgagtaagt acgaagattg
     2521 gataacatca aagaaagcag atactggcaa ggctatctct tctaaatttt caaccacagg
     2581 acttggataa aggataatct gactatcctt gtaatcaaaa ttccatgcag acaagtcttg
     2641 gtcagagaag ttttttacaa tctgctcact ctggtcttga tctatttttt tatcctctat
     2701 gaaggaggtc aactctttta tcagctgttc cttagcctta ctagcatctg aaaacagttg
     2761 gtcaagtgta aaaggttgcc catcttctgt taagtgaacc tttcctagac tggtcttttc
     2821 agtctcttca atcttaaaag caactaaatc atagatttgt ttggtcacat tacgattaac
     2881 gactcccttt aaacctgact cttcttgctc tgtatagtag aaaacaagat tgtccttact
     2941 ttctagcttg tccttaacat cttgatttat cagctcccta acagaggaaa tcactttctc
     3001 cccttggaga ggataatagg caatcacttc ggcttgcccc tgacgaaaat gctccttctg
     3061 atttccctca ctcaattgat catctttctc ttttttgagc gattcaatct tttgctcaaa
     3121 acttttttgc tggtagatct taaaagcaat aaatccgcct aataggcaaa tagaaattgc
     3181 taaaatacca atcaaagcca ataatacatg tctcgttttc ccgtgtctgc cacgtcctag
     3241 tctactttta ttcatattta tatcataaca aatttgagca ataatttcaa tgatacaatt
     3301 tggcaatcca caattcctct agcaagccaa agcatcttac atcaactcca acatccgtat
     3361 ctgtagagat tatgtagttt tctatctatg gaatttctag tagattgaag ctagaatagt
     3421 agacctatac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct
     3481 gttctcattt cattttacta taaaactatg aaaagctagg tcatctgaga agtaattact
     3541 atcgacaatt gcgatagcgt atactagtgc gatttgtttg tagctctggt gggtatcacc
     3601 ttcacgttgg cgaatttttt ctaggttttg attaacctga ctgcacagat aagcccatag
     3661 gcgattgatg aaaaaattct gatgatgaac ctgaatttcg atgataactt ggattccatt
     3721 atctaactcc gccaagacgt ctatactagt atagaaatct tgcgctgagt agggcatgga
     3781 aggcaagacg tgaatgttac ttccctccaa aatcgtcaca ttttttgctg gcaagtccag
     3841 catatcgcgg ataaattgac aaatcattag ttgggctgat acctggatgt ctgagaatcc
     3901 tccttttcct ccttctatta tagcacattt ttaaatctag gtttgctaga ttctatgctt
     3961 ctatctattt attcggaaaa gaaagctaat agcttatttg aaattttctc ctctctgttg
     4021 gatagtcccg tctatctatg ttataatgaa agaaggattt aaaatcggaa aaggagtatt
     4081 tatgctaaaa ttaggtgtca tcggaactgg cgctatcagc catcatttca tagaagcagc
     4141 ccataccagt ggagaatacc aactggtcgc aatctattct agaaaactag aaactgcagc
     4201 aacctttgct tctcgctatc agaatatcca actattcgat caattagaag tcttcttcaa
     4261 atcttctttt gatttagtct atatcgccag tccaaactcc ttacattttg ctcaggcaaa
     4321 agctgccttg tctgctggta aacatgttat tctcgaaaag ccagctgtca ctcaaccaca
     4381 agaatggttt gatttgattc aaacagctga aaaaaataac tgttttatct ttgaagcagc
     4441 tcgtaattac cacgagaaag cctttactac tatcaaaaac tttttaacag ataagcaagt
     4501 gttaggagca gatttcaact atgccaaata ctcttccaag atgcctgact tgttggctgg
     4561 acaaacacca aatgtctttt cagaccgttt tgctggtgga gccctcatgg atttggggat
     4621 ttatcccctc tatgctgctg ttcgtctttt tgaaaaagct aatgacgcga cttaccatgc
     4681 tcaacagctt gacaatagca ttgacctaaa tggagatggt atcctcttct acccagacta
     4741 tcaagttcac atcaaggctg gaaaaaacat cacttccaat cttccttgcg agatttatac
     4801 aacagatgga accttgactc tcaacacgat tgagcatatt cgctcagcta tttttaccga
     4861 ccaccaagga aatcaagtcc agcttcctat ccaacaggct cctcatacga tgactgagga
     4921 agtcgctgca tttgcacaca tgatccagca accagatctg aatctctaca aaacttggct
     4981 gtatgatgca ggctctgttc atgagctact atataccatg cgccagactg ctggcattag
     5041 atttgaggca gaaaaatgaa aaccaaacta ccgactgaat ggcaagaact gagtgaccaa
     5101 ctcggtttcc aagaattcac ccccattcaa actcaactat ttgagcccct tcttgctgga
     5161 gaaaacctcc taggagtgag ccaaaccgga actggtaaga ccctagcgta tctcctacca
     5221 agtcttctca gactacaaaa gaaaaaagcc caacaactct tgattctagc accaaacacg
     5281 gaacttgctg gacagatttt tgatgtatgt aaaacgtggg cagaagctat cggattgact
     5341 gctcaactct tcctttcagg ttcaagtcag aaacgacaaa ttgaacgtct taaaaagggg
     5401 ccagaaattc tgattggaac tcctggccgt atctttgaac tcattaaact taaaaaaatc
     5461 aagatgatga atgtggaaac catcatcctg gatgaatttg accaattact agatgattct
     5521 cagattcact ttgtagaaaa aatcactcac tacgcacctc gtgaccacca actggtctac
     5581 atgagtgcca cgaccaagtt tgaccaagaa aagattgtgc cgaatacacg cactattgat
     5641 ctctctgacc aaaaattgga caatatccag catttctaca tgcaggtaga ccaacgtcat
     5701 cgagtggata tgctacgaaa actggctcat gtagaggatt tccgtggtct agtcttcttc
     5761 aatagcctgt cagaccttgg gaatgccgag gaaaaactac agtatcgtga tatattgact
     5821 gtttccctcg ctagtgatgt taatgttaaa tttagaaaaa tcatcttaga aaagtttaaa
     5881 gataaccaac taaccctgct tcttgcaact gaccttttgg ctcgtggaat tgatatcgat
     5941 agcctagaat gtgtcgtaaa ctttgatatt cctagagata gcgaaaccta cacacaccgt
     6001 gctggtcgta ctggccgtat aggcaaggaa ggatatgtta ttactctcgt cactcatcca
     6061 gaagaaatca aaaaacttaa aaagtttgca agtatccgag aaattgtcct aaaaaaccaa
     6121 gaactctata tcaaataaag ccccattgct ctatacacat ccagtgtatg gagctttttt
     6181 ataagcaatt caattttata ctcatctgct ttcaaaaagc attctattcc atctccgatt
     6241 aacgatggac tttatcacct ccttctccag tccttgtatg acatcttgga gttgattcat
     6301 gacatcttcc aaagttcgaa aggctttatt cttaaatcca cgtttacgaa tctctttcca
     6361 cacttgttca atgggttcat ctctggtgtg tatggaggaa taaaggtaaa atcaatatta
     6421 gtcggaatct ttaaggtact tgatttatgc catatagcat tgtccataac gagtaaaaaa
     6481 taatcatctg gataagcttg tgaaagctct tctaaaaagg cgttcatcca ctcagtatta
     6541 catccaccag ctattaagaa aaatgattcg cctgtatggg catcaacagc tccataacaa
     6601 tagcgaaatt ctcgtatata gtgactatgg acatgtggac ctactcctat tggagaccaa
     6661 caagatccca gtttactgat tctaccgaaa ccagcctcat cttggtacat caagcgaacc
     6721 ttatgaaaag gtctactggt ttta
//
LOCUS       DAVBNZ010000085         6726 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000085 DAVBNZ010000000
VERSION     DAVBNZ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.086"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            138..860
                     /locus_tag="VQ860_002006"
     CDS             138..860
                     /locus_tag="VQ860_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3120376.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1077..2411
                     /gene="pepC"
                     /locus_tag="VQ860_002007"
     CDS             1077..2411
                     /gene="pepC"
                     /locus_tag="VQ860_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET3120377.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSR
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAVLNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(2467..3378)
                     /locus_tag="VQ860_002008"
     CDS             complement(2467..3378)
                     /locus_tag="VQ860_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3120378.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3402..4205)
                     /locus_tag="VQ860_002009"
     CDS             complement(3402..4205)
                     /locus_tag="VQ860_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET3120379.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ860_002010"
     CDS             complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ860_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET3120380.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ860_002011"
     CDS             complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ860_002011"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET3120381.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKI
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         2017 a         1388 c         1478 g         1843 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacatata tacggcaagg cgacgttgac gcggtttgaa
       61 gagatttttg aagagtatga aacgaaaagg aggttggtca ttgtactagc ctccttttga
      121 tatgatataa tagttctatg agattagata aatttttagt tgcctgtgcg gtgggaagtc
      181 ggactgaggt caaaaacttg ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa
      241 aatcagctaa attgcagatt gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt
      301 tggagtatga agagtttgtc tactacatga tgaacaagcc caaaggagtt atctcagcga
      361 ctgaggatcc caagcacaga accgttctgg acttgttgga tgacttggcg cggagtaagg
      421 aagttttccc agtaggacgc ttggatattg acacgcatgg tcttttgctc ttgaccaatg
      481 atggtcagct ggctcatgtt cttctttcgc ccaagcgtca tgtggacaag acttatctgg
      541 cacaagtcaa gggaatcatg acccaagaag atgtggagac atttgctgag ggtattcctc
      601 tcaaagactt tacctgtcaa cccgctatac tggagcttgt atccatagat acagaaaaga
      661 atcaaagcca aatccgtgtg accattgcag aagggaagtt tcatcagatc aagcgtatgg
      721 tgggctactg tggcaaggaa gtggtggact tgcaacgatt gactatggga actttagtat
      781 tagatgagaa cctggaacga ggggaatggc gtcgcttgac caaggaagaa ttagaaattc
      841 tccgcgctaa tattatttaa tttagtttaa tactcaatga aaatcaaaga gcaaactagg
      901 aaactagccg caggctgtac ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat
      961 tttcgaagag tataaattcg aaaaaggtga gggacaatgt cctcgccttt tatgtttttt
     1021 agttgcttcc tttgtgaaaa gagttataat agactgtaga ataaaaggag gaatctatga
     1081 acgcgattca agaatcattt actgataaac tatttgccaa ctatgaagca aatgtaaaat
     1141 accaagcgat tgaaaatgct gccagccaca acggaatttt tgcagctctg gaacgtcgcc
     1201 aaagccgtgt agacaacaca cctgttttct cattggattt aaccaaggac aaggtcacta
     1261 accagaaagc gtctggtcgt tgctggatgt ttgcggctct caacaccttc cgccacaaac
     1321 tcatctcgca atacaaattg gagaactttg agttgtcaca agcccacact ttcttctggg
     1381 ataagtatga gaaatcaaac tggttcttgg agcaagtcat tgcgacttca gaccaagaat
     1441 tgactagccg caaggttagc ttcttactcc aaacacctca acaagatggc ggtcaatggg
     1501 atatggtcgt ttccctcttt gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt
     1561 ctgtttcatc tagcagcagt cgtgagctaa atgcggtcct taataaattg cttcgtcaag
     1621 atgctcaaat cttgcgtgat ttgcttgttt ctggtgcaga tcaagtgact gttcaagcta
     1681 agaaagaaga cctcttgcaa gaaatcttta actttcttgc tatgtcatta ggacttccac
     1741 cacgcaagtt tgactttgct tatcgcgata aagataacaa ctacaaaagt gaaaaaggaa
     1801 tcacaccaca agagttctac aagaaatatg tcaatcttcc tttagaagac tacgtttctg
     1861 ttatcaatgc tccaactgct gataaacctt acggaaaatc ttacacagtt gagatgttgg
     1921 ggaatgtggt tggtagccgt gcagttcgtt acatcaacgt tccaatggag cgcttgaaag
     1981 aattggcgat tgcccaaatg caagcaggtg agactgtttg gtttggttct gatgtcggcc
     2041 agctcagtaa ccgtaaggct ggaatccttg cgacagatgt ttatgacttt gaatcaagca
     2101 tggacattaa acttactcaa gacaaggctg gacgtttgga ctatagcgaa agcttgatga
     2161 cccacgccat ggtcttgaca ggtgttgact tggacgaaaa tggtaaatca accaagtgga
     2221 aggttgaaaa ctcatgggga gacaaggtcg gtacagatgg ttactttgtt gcctcagacg
     2281 cttggatgga cgaatacaca taccaaatcg ttgttcgtaa ggaattgctg acagcagaag
     2341 aacaagctgc ctatggagca gaaccaattg tacttgcacc atgggatcca atgggagcct
     2401 tggctgaata aaagcataga aaaaaggaat cagattttag aacctggttc ctttttagtt
     2461 gcttgattac atgatgtgaa gaacatgtgc cacaataccc actgcgaaga gagcaaggat
     2521 aatagtgatt ggagatactt ttttcttaag taagtacatg caaagtaaag taaggagtag
     2581 tcctgataat ccaggaatca acatatccaa gttttgttgg aaagtagtaa ctttttcagg
     2641 agtttgagac aatccttgtc ctacttgtgc gaatgcttct tggatacctt tagacccttc
     2701 tggcaattta tcccaatgga tataagcctt ttcatctagt tgaactttag aaacatcgaa
     2761 agcaaattta atatttaccc agcgttgaac aaggacagca agaatgaaca tcccaaggat
     2821 agaagctcct ttagtgatat cttgaaggat accaccagac atatctttag tgatttctga
     2881 tccagcctta tatccaatct cttgaacata ccacaagaat gacatacgaa tcaagttcca
     2941 tgcaacaaag aagaggagtg gacccaagat attgccagta agggcaagtg aagcaccgag
     3001 agatccaagg attgggcgca ctgtaaacca gaatactggg tcaccgatac cagcaagagg
     3061 tcccatcata ccgattttaa ccccttggat agcagcgtca tcgatttcca caccgttagc
     3121 acgttcttct tcaagcgcaa gagtaacccc catgactgga gcagctacgt atggatgagt
     3181 gttgaagaac tcaaggtgac gctcaagagc agcgatttga tcttcttttt tagtatagag
     3241 ttttttgata gctggaatga gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt
     3301 ccaagaccct tgtaagaagg ttgaacgcca ccaaactttt ttacgatctg atttagttaa
     3361 ttgaagtttt tcagtcatga tgttttcagt cctttcttat cttagtagtc ttctaggata
     3421 tcgccgattg ggtcgttaga agttgcggct cctccgccac catttccacc agttttagaa
     3481 aggtgaaggt agataagagc gatagcaacg ccgatagcac cgaatccgat tagagtaata
     3541 tctgacacag cagcgagaac gaaaccaaga gcgaagaatg gccatacttc acgagttgcc
     3601 atcatgttga taaccatggc gtaaccaacg gcaacgacca taccaccacc gatagccata
     3661 ccatctttga gccagtctgg catggcacta aggatacttt gtacagtttc agttggtacc
     3721 ataaggagaa gagctgcagg aagcgcgata cgaagtcctt ggaaaagtag cgcgatgaaa
     3781 tgcgcacgct ccacagcgcc gaagtcacct tttttagcgg cagcatctgc agtatgaacc
     3841 aaaccaactg aaattgtacg aacaatcatt gtcaagaaaa gtccagctac agcaagaggg
     3901 atagcaaccg cttgggcaac accgatacca gtcttggtaa agtcaccacc aagaaccatg
     3961 ataatggcag cagcgacaga agcaagtgca gcatcaggag cgatagcagc accgatattt
     4021 gaccaaccaa gggcaatcat ttgaagcgat ccaccgagga taatccctgc ttccaagtga
     4081 cctgttacaa gcccaataag ggtacaggct acaagtggtt ggtgaaattg gaactggtcg
     4141 aggatgcctt caagacctgc aaagaaggct acaacgacta ctaaaaccat agaaataata
     4201 gacatgttta aaatcctttc ataaataatg gcttatttga cattggcttt gttaatcaag
     4261 tcaaacaaat cttttttaga atcatttggt actttacgga catcaaattc aacacccaag
     4321 tcacgcattt tttcaaatgt agcaacgtct tctttgtcca tagacaaaac ggtattgacc
     4381 aatgttttac ctgttgagtg agccatagaa ccaacattaa gagtcttgat tggcacgccg
     4441 ccttcgatgg cacgaagggc atcttgaggt gtttcaaaca agataagggc atgtgtttct
     4501 ccaaaacgtg ggtcttttga aatctcaatc agtttttgaa ttggaaccac gttagccttg
     4561 acattacctg gagctgcttg tttaatcaat tctttacgaa ggtcgtcttt agccacgtta
     4621 tctgaagcaa cgatgatacg atttgctttt gaatctggag tccaagcagt tgcaacctga
     4681 ccgtgaagta gacgtgtgtc aagacgggca agattgattt tcaatttacc gtctccgata
     4741 acagttcctt ctgggatagc agtttgggca actggagcag ctgcagcgct tgcaacttct
     4801 tcgactggat ttagctcttc tggaagagct ttgatgccat ctttggcttc tttaatgata
     4861 ttagcagcga ctttttctac acctgcagca gcgtccatga ggcgctctgt gtaggcttga
     4921 atcaacatcg gtaagttaag tcctgtgatg atggcaaact tacgctcagg attttctccc
     4981 atcacgcgac tagcttggtt aaatggagaa ccactccaaa ggtcagccaa aactagaacc
     5041 tcatcttctg cgtcaaatgc agcaacagcg ttattaaact tagcgtatag atcatcagga
     5101 ccttcatttg gcataaaggt cacaacttga accttttctt gttcaccaaa gatcatagat
     5161 cctgactgat gaatacccgc agcaaattcg ccgtggctcg caataatgat tccgatactc
     5221 attattgtca ttcctccttt tttgttttag ttttcattta agaaaacttt aagactgttt
     5281 aagtataaac cgttttcata aaaaaagcaa ctatttatca taaaaaatta aaaaattttt
     5341 atttttgtat gttgatatgt tgagtttttg aggagtaatc ttgaattctt atttaaaatt
     5401 taatataaaa aagttggaag aagcttccaa cttttaaaat aggtttctat tagattagtg
     5461 ggtgaagtcg agtaccatac gtccttggat ttggcctttt tccatttcgt cgaaaatggc
     5521 aacagcatct tctactggac gtttttgaac aactgggact accagacctt ctgcaccaaa
     5581 ttggaaggct tcttctaagt ctttacgagt tccgacaaga gaaccgatga cttggattcc
     5641 atcgaggact gttttaacga tgctgagttc catcatttca gaaggaagac caacagcgac
     5701 gacgcgacca ccagcacgaa tggagtcaac agcctggttg aaggcaactt tagacacagc
     5761 agttacgaca gctgaatgag ctcctccatc agttttttct ttaatgagtc cagctacatc
     5821 ttcaacttcg aggccgttaa tcacaatgtc agcgcctact tcttttgcaa gggcaagttt
     5881 gtcattgttg atatcgactg cgataacatg agcattgaat acttttttag cgtattgaac
     5941 agcgaggtta ccaagtccac cagcaccgta aagaacaacc cattggcctg gttcaatttt
     6001 tgcttctttg atagctttat aggttgttac tccagcacat gtgatagaag aagcttgggc
     6061 tggatcaagt ccgtcaggaa ctttgacagc atagtcagca gttacgatac attgttcagc
     6121 cataccaccg tctactgagt agccagcatt tttcactgta cggcaaaggg tttcgcgacc
     6181 agttgtacag tattcgcaag tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc
     6241 accgacttta aggcttttca catctggagc aatctcttta acgataccga taccttcgtg
     6301 cccaagaaca cgtcctggga cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg
     6361 gcaaacacca cagtattcaa cttctacaag tgcttcccca gtttcaagtg gacggagtac
     6421 tttttcttca atagcaacac cagtgctttc tggatttaca acaacagctt tcatagctat
     6481 cctccttgat attgaccgag aacagggaca acgggactgg attgattttt tgtcaacaga
     6541 gtcgagtgtg acgagctctc ttgtatttat atgtgaagta tatcacaaaa gaaagccttt
     6601 tccaaggttt tggagacaaa aagtagaaca atcgattaac tggttgatga gactgtgaaa
     6661 agagcacaaa gaccagcttg caagctggtc atactcttcg aaaatctctt caaaccacgt
     6721 cagctt
//
LOCUS       DAVBNZ010000086         6627 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000086 DAVBNZ010000000
VERSION     DAVBNZ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6627
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.087"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            170..370
                     /locus_tag="VQ860_002012"
     CDS             170..370
                     /locus_tag="VQ860_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120382.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDQK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            412..816
                     /locus_tag="VQ860_002013"
     CDS             412..816
                     /locus_tag="VQ860_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120383.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ860_002014"
     CDS             1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ860_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3120384.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ860_002015"
     CDS             1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ860_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET3120385.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDASNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAETAFKEMN"
     gene            2697..4088
                     /locus_tag="VQ860_002016"
     CDS             2697..4088
                     /locus_tag="VQ860_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET3120386.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIIAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLILLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ860_002017"
     CDS             4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ860_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET3120387.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDSDVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5156..>6627
                     /gene="phtB"
                     /locus_tag="VQ860_002018"
     CDS             5156..>6627
                     /gene="phtB"
                     /locus_tag="VQ860_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET3120388.1"
                     /translation="MKINKKYVAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSD
                     LSASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISS
                     LLRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRI
                     ARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPSNPIDEKLVKEAVRKVGDGY
                     VFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYD
                     LLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLV"
BASE COUNT         2032 a         1215 c         1411 g         1969 t
ORIGIN      
        1 gtaaaatgaa ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagt ccatatgtac tattctagtt tcaatatatc ataactgttc ctagtcaacc
      121 tgcaagccct atcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag
      181 cgcttcggct agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagctag accaacgctt gaaagctttg gcaacagtat ctgatcagaa
      301 aatcgatgca accaaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgggctgc cttggactct
      421 ctcaaagatg tgaaagcaaa tgctagcgac agcaagcctg cacaggacaa gaaggatgca
      481 aaacaaggaa cggaagatag taaggattca gataagatga ctgaaacaaa ctcagttccg
      541 gcaggagtga ttgtggtcag tctacttgcc ctcctaggcg tgattgcctt ctggctgatt
      601 cgccgtaaga aagagtcaga aatccagcaa ttaagcacgg aattgatcaa ggttctagga
      661 cagctagatg cagaaaaagc ggataaaaaa gtccttgcca aagcccaaaa ccttctccaa
      721 gaaacccttg atttcgtgaa agaagaaaat ggctcagcag agacagaaac taaactagta
      781 gaggagctta aagcaatcct tgacaaactc aagtaaaaca tgatttatga aatgtcagac
      841 ctaaaagaca ttttcgttca caaaagcagc gatgagtaat ccttgtcgtt gctttttggc
      901 tattttgggg gataagatcc gccttgacta gcaaaagaaa agattggtcc aatagtgccc
      961 gatacgattt tgcgtagcag aaagcttaca aataaaattg aatatagtaa aataggatta
     1021 gaattattaa gaaagttggt tctttattgg aaacgatagt atttttaatc tctgtttttc
     1081 tagcaggtgt tttatccttt ttttctcctt gtatttttcc tcttctgcca gtctatgctg
     1141 ggattttatt ggatgatcaa gaaagtgcaa aaagcttttc tttgtttggg agaaaggttc
     1201 tctggtcagg cttgattcga acactttgct ttatcgctgg tatctctctc attttcttta
     1261 ttctaggctt tggtgctggt tactttggtc atattctcta tgcaaattgg tttcgatatg
     1321 gcatgggagc tattattatc attttgggtc ttcaccagat ggaaattttt catttgaaga
     1381 aattagaagt tcaaaaaagt tttaccttta aaaaatcaga ttctaatcgt tattggtcag
     1441 cttttttact tggtattacc tttagctttg gttggacacc ttgtattggt ccagttttaa
     1501 gttctgtttt agcacttgcg gcttctggag gcaatggcgc ttggcaagga gcgatttata
     1561 ctctcattta cactctgggc atggcccttc ctttcttggt attggcacta gcttcaggtc
     1621 tagtcatgcc atattttagt aaaatcaagc gtcatatgat gctactaaag aaaattggtg
     1681 gtttcctcat tgttttaatg ggaattttgt tactattagg acaagtaaat gttctagctg
     1741 gaatttttga ataaaggagg acaaatgaaa aaagtaatgt ttgctggctt aagtctcttg
     1801 tcattagttg tattgatggc ctgtggtgag gaagaaacta aaaagactca agcagcacaa
     1861 cagccaaaac aacaaacgac tgtacaacaa attgctgttg gaaaagatgc ttcaaacttc
     1921 acattgcaat ccatggatgg caaagaagtt aagttatctg attttaaggg taaaaaggtt
     1981 tacttgaagt tttgggcttc atggtgcggt ccatgcaaga aaagtatgcc agagttgatg
     2041 gaactagcgg cgaaaccaga tcgtgatttc gaaattctta ctgtcattgc accaggaatt
     2101 caaggtgaaa aaactgttga gcaattccca caatggttcc aggaacaagg atataaggat
     2161 atcccagttc tttatgatac caaagcaacc accttccaag cttatcaaat tcgaagcatt
     2221 cctacagaat atttaattga tagccaagga aagattggaa agattcaatt tggtgctatc
     2281 agtaatgcgg atgcagaaac agcatttaaa gaaatgaact agaatcgata aaatctgatt
     2341 acaagatgta gtcagatttt ggtaacttct aaaactaact tccagtttcc cacaacctag
     2401 cttttagtat gagaaaaacg cgtgacatca gtggaaatcc gtcttagact aacttccact
     2461 ggttttcttt ttcttgatat ataagggttc aaaagcgaaa agactcagaa aaaagtgcac
     2521 gacaaatagc cctaaaacag agtcgtttta gagtaacttc cagttttggg agagagatgg
     2581 aagttacttt gagaagttac ggtagtcaga tttttttaga aaaacatttt ataaatattc
     2641 acatatctcc tatatttatg gtaaaataga atcatcagtt tattttggag tcaaagatga
     2701 atatatttag aacaaagaat gttagtttag ataaaacaga gatgcatagg catttgaagt
     2761 tatgggattt gattttgctg ggtattggag ccatggtagg gacaggtgtc tttacaatca
     2821 caggtactgc agctgctaca cttgctggtc cagcactagt gatttcaatc gttatttctg
     2881 ccttgtgtgt gggattatca gccctctttt ttgcagaatt tgcctcgcga gtacccgcta
     2941 caggaggtgc ctatagttac ctctatgcta tcttaggaga attccctgcc tggttggctg
     3001 gttggttaac catgatggag ttcatgacag ccatatcagg cgtagcttcg ggttgggcag
     3061 cttattttaa aggcttgctc tctcaatacg ggatagccct tcctcaggct ttaaatggta
     3121 cctttaatcc tcaagcaggg acatttgttg atttattgcc tattcttgtc ttggtcttgg
     3181 tgacttcgct tgttttacta aatgccaagg cagccttacg ctttaattcg attctagtta
     3241 ttttgaaatt ttccgcttta gctctctttg ttttagtagg aatttggaat attaagtttg
     3301 ataattggag caattttgct ccttacggtt ttggacaaat ctatggagct agtactggta
     3361 ttatagctgg tgcgtccttg atgttcttcg gttttttggg atttgaatcc atctctatgg
     3421 ctgtagatga agtcaagact cctcaaaaaa atattcctag agggattgtc ttatcgcttt
     3481 ctatcgtaac cattctctat gccttggtga cccttgtttt gactggtgtg gttcactata
     3541 gtcatttaaa tgtcgatgat gccgttgcct ttgcccttcg tagtgttggg attagttggg
     3601 cagccaacta tgtgtcatta gtggctatct tgaccttgat tacagtttgt atttcgatga
     3661 cctatgccct atcgcgtatg atttacagtt tagcacgtga tggcttagtg cctgctgcct
     3721 ttaaggaact gacgaagact agcaagatac caaagaatgc tactatcttg acaggtctag
     3781 cttcagcagt agcagcagga atgttcccgc tagccagtat tgcagccttt ttaaatattt
     3841 gtaccttagc ctacttgatc ctgctggctt atggtctgat tcgcttacgg aaagaaaaag
     3901 gaatgcccaa agctggggaa tttaaaacac cattggtacc tctgttacca attttatcga
     3961 tcatcatttg tttatccttc atgttacagt ataatatgaa tacctggatt gctttcctag
     4021 ttgcgttgtt agtaggaagt attatttact tcacttatgg ctataagcat tctaccatag
     4081 aagaataaag tgaaagtcta ttgagttgtt gacactcagt agatttttat atgtgaaaga
     4141 aatttcaaat tttttctaaa aatatcttga cagattaaat tttcaggagt agaatattta
     4201 ctagttaatt aaatggttaa ggagttgttc atgaagaaac aaaatttatt tttagtcctg
     4261 ttaagtgtct ttcttttgtg cttgggggct tgtggtcaaa aggaaagtca gacaggaaag
     4321 gggatgaaaa ttgtgaccag tttttatcct atctacgcta tggttaagga agtatctggt
     4381 gacttgaatg atgttcggat gattcagtca agtagtggta ttcactcctt tgaaccttcg
     4441 gcaaatgata tcgcagccat ctatgattca gatgtctttg tttaccattc tcatacactc
     4501 gaatcttggg caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa ggtcttagag
     4561 gcttctgagg gaatgacctt ggaacgtgtc cctggactag aggatgtgga agcaggggat
     4621 ggagttgatg aaaaaacgct ctatgaccct cacacatggc tagatcctga aaaagctgga
     4681 gaagaagccc aaattatcgc tgataaactt tcagaggtgg atagtgagca taaagagact
     4741 tatcagaaaa atgcgcaagc ctttatcaaa aaagctcagg aattgactaa gaaattccaa
     4801 ccaaaatttg aaaaagcgac tcagaaaaca tttgtaacac aacatacagc cttttcttat
     4861 ctagcgaaga gatttgggct taatcaactt ggtattgcag gcatctctcc tgaacaagaa
     4921 ccaagtccac gacaattaac agaaattcag gaatttgtta aaacctataa ggttaaaacg
     4981 atttttacag aaagtaatgc ttcttcaaaa gtagctgaaa ctcttgtcaa atcaacaggt
     5041 gtgggtctta aaactctgaa tcctttagag gcagacccac aaaatgacaa gacctattta
     5101 gaaaatctgg aagaaaatat gagtgttcta gcagaagaat taaagtgagg aaagaatgaa
     5161 aatcaataaa aaatatgtag caggttcagt ggcagttctt gccctaagtg tttgttccta
     5221 tgaacttggg cgttaccaag ctggtcagga taagaaagag tctaatcgag ttgcttatat
     5281 agatggtgat caggctggtc aaaaggcaga aaatttgaca ccagatgaag tcagtaagag
     5341 ggaggggatc aacgccgaac aaatcgtcat caagattacg gatcaaggtt atgtgacctc
     5401 tcatggagac cattatcatt actataatgg caaggtccct tatgatgcca tcatcagtga
     5461 agagctcctc atgaaagatc cgaattatca gttgaaggat tcagacattg tcaatgaaat
     5521 caagggtggt tatgtcatta aggtaaacgg taaatactat gtttacctta aggatgcagc
     5581 tcatgcggat aatattcgga caaaagaaga gattaaacgt cagaagcagg aacacagtca
     5641 taatcacggg ggtggttcta acgatcaagc agtagttgca gccagagccc aaggacgcta
     5701 caccacagat gatgggtata tcttcaatgc atctgatatc attgaggaca cgggtgatgc
     5761 ttatattgtc cctcacggca atcacttcca ctatattcct aagagtgatt tgtctgccag
     5821 tgaattagct gctgcccaag cctattggaa tgggaagcag ggatctcgtc cttcttcaag
     5881 ttctagtcat aatgcaaatc cagctcaacc aagattgtca gagaaccaca atctgactgt
     5941 cactccaact tatcatcaaa atcaagggga aaacatttca agccttttac gtgaattgta
     6001 tgctaaaccc ttatcagaac gccatgtgga atctgatggc cttattttcg acccagcgca
     6061 aatcacaagt cgaaccgcca gaggtgtagc tgtccctcat ggtaaccatt accactttat
     6121 cccttatgaa caaatgtctg aattggaaaa acgaattgct cgtattattc cccttcgtta
     6181 tcgttcaaac cattgggtac cagattcaag accagaacaa ccaagtccac aaccgactcc
     6241 agaacctagt ccaagtccgc aaccagctcc aagcaatcca attgatgaga aattggtcaa
     6301 agaagctgtt cgaaaagtag gcgatggtta tgtctttgag gagaatggag tttctcgtta
     6361 tatcccagcc aaggatcttt cagcagaaac agcagcaggc attgatagca aactggccaa
     6421 gcaggaaagt ttatctcata agctaggagc taagaaaacc gacctcccat ctagtgatag
     6481 agaattttac aataaggctt atgacttact agcaagaatt caccaagatt tacttgataa
     6541 taaaggtcga caagttgatt ttgaggcttt ggataacctg ttggaacgac tcaaggatgt
     6601 ctcaagtgat aaagtcaagt tagtgga
//
LOCUS       DAVBNZ010000087         6219 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000087 DAVBNZ010000000
VERSION     DAVBNZ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6219
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.088"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            70..608
                     /locus_tag="VQ860_002019"
                     /pseudo
     CDS             70..608
                     /locus_tag="VQ860_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            675..1085
                     /locus_tag="VQ860_002020"
     CDS             675..1085
                     /locus_tag="VQ860_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET3120389.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1201..3318
                     /locus_tag="VQ860_002021"
     CDS             1201..3318
                     /locus_tag="VQ860_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PavB family fibronectin-binding SSURE repeat
                     adhesin"
                     /protein_id="HET3120390.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFYQLALD
                     GNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTININGLISK
                     ETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKAS
                     DKAPWSDNGDAKNPALSPLGENVKTKGQYFYQVALDGNVAGKEKQALIDQFRANGTQT
                     YSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHN
                     HATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASI
                     GLLGLALAGLLGGLGLKNKKEEN"
     gene            3485..4183
                     /locus_tag="VQ860_002022"
     CDS             3485..4183
                     /locus_tag="VQ860_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3120391.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            4180..5232
                     /locus_tag="VQ860_002023"
     CDS             4180..5232
                     /locus_tag="VQ860_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3120392.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            5427..6038
                     /gene="rpsD"
                     /locus_tag="VQ860_002024"
     CDS             5427..6038
                     /gene="rpsD"
                     /locus_tag="VQ860_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET3120393.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
BASE COUNT         1921 a         1226 c         1390 g         1682 t
ORIGIN      
        1 gacgttgacg cggtttgaag agattttcga agagtataag aaaaaatcag tcccctaaag
       61 gagcagatta tgaagttatt gtctatcgcc atttctagct ataatgcagc agcctatctt
      121 cattactgtg tggagtcgct agtgattggt ggtgagcaag ttgggatttt gattatcaat
      181 gacgggtctc aggatcagac tcagaaatcg ctgagtgttt agctagcaag tatcctaata
      241 tcgttagagc catctatcag gaaaataaag gccatggcgg tgcggtcaat cgtggcttgg
      301 cagaggcttc tgggcgctat tttaaagtag ttgacagtga tgactgggtg gatcctcgtg
      361 cctacttgaa aattcttgaa accttgcagg aacttgagag caaaggtcaa gaggtggatg
      421 tctttgtgac caattttgtc tatgaaaagg aagggcagtc tcgtaagaag agtatgagtt
      481 acgagtcagt cttgcctgtt cggcagattt ttggctggga ccaggtcgga aatttctcca
      541 aaggccagta taccatgatg cactcgctga tttatcggac agatttgttg cgtgctagcc
      601 agttctaact gcctgaacat actttttatg tcgataatct ctttgtcttt acgccccttc
      661 agcaggtcaa gaccatgtac tatctgcctg tcgatttcta tcgttatttg attgggcgtg
      721 aggaccagtc tgtcaatgag caagtgatga ttaagtgcat tgaccagcaa ctcaaggtca
      781 atcgactctt ggtagaccaa cttgatttgt cccaagtgag tcatcccaaa atgcgagaat
      841 atctgctgaa tcatattgaa atcacgacgg tgatttccag taccctgctc aaccgatctg
      901 gaacagcgga gcatctggca aaaaaacgcc aattgtggac ctatattcag cagaaaaatc
      961 cagaagtctt tcaggctatt cgtaagacca tgttgagccg tttgaccaaa cattctgtct
     1021 tgccagatcg caaactgtcc aatgtcgtct atcaaatcac caaatctgtt tatggattta
     1081 attaatataa gtgttttata agagggattt aagaaaaatt ttaacttttt cttagtcctt
     1141 tttaatttca ggagattata ctagagtcat caaataaaga aagactctaa ggagaatcct
     1201 atgaaattca atccaaatca aagatatact cgttggtcta ttcgccgtct cagtgtcggt
     1261 gttgcctcag ttgttgtggc tagtggcttc tttgtcctag ttggtcagcc aagttctgta
     1321 cgtgccgatg tggtcaatcc gaccccaggt caagtcttac ctgaagagac atcgggaacg
     1381 aaagagggtg acttatcaga aaaaccagga gacaccgttc tcactcaagc gaaacctgag
     1441 ggcgttactg gaaatacgaa ttcacttccg acacctacag aaagaactga agtgagcgag
     1501 gaaacaaact cttctagtct ggatacactt tttgaaaaag atgaagaagc tcaaaaaaat
     1561 ccagagctaa cagatgtctt aaaagaaact gtagatacag ctgatgtgga tgggacacaa
     1621 gcaagtccag cagaaactac tcctgaacaa gtaaaaggtg gagtgaaaga aaatacaaaa
     1681 gacagcatcg atgttcctgc tgcttatctt gaaaaagctg aagggaaagg tcctttcact
     1741 gccggtgtaa accaagtaat tccttatgaa ctattcgctg gtgatggtat gttaactcgt
     1801 ctattactaa aagcttcgga taatgctcct tggtctgaca atggtactgc taaaaatcct
     1861 gctttacctc ctcttgaagg attaacaaaa gggaaatact tctatgaagt agacttaaat
     1921 ggcaatactg ttggtaaaca aggtcaagct ttaattgatc aacttcgcgc taatggtact
     1981 caaacttata aagctactgt taaagtttac ggaaataaag acggtaaagc tgacttgact
     2041 aatctagttg ctactaaaaa tgtagacatc aacatcaatg gattagttgc taaagaaaca
     2101 gttcaaaaag ccgttgcaga taacgttaag gacagtatcg atgttccagc agcctaccta
     2161 gaaaaggcca agggtgaagg tccattcaca gcaggtgtca accatgtgat tccatacgaa
     2221 ctcttcgcag gtgatggtat gttgactcgt ctcttgctca aggcatctga caaggcacca
     2281 tggtcagata acggtgacgc taaaaaccca gccctatctc cactaggtga aaacgtgaag
     2341 accaaaggtc aatacttcta tcaattagcc ttggacggaa atgtagctgg caaagaaaaa
     2401 caagcgctca ttgaccagtt ccgagcaaat ggtactcaaa cttacagtgc tacagtcaat
     2461 gtctatggta acaaagacgg taaaccagat ttggacaaca tcgtagcaac taaaaaagtc
     2521 actattaaca taaacggttt aatttctaaa gaaacagttc aaaaagccgt tgcagacaac
     2581 gttaaggaca gtatcgatgt tccagcagcc tacctagaaa aggccaaggg tgaaggtcca
     2641 ttcacagcag gtgtcaacca tgtgattcca tacgaactct tcgcaggtga tggtatgttg
     2701 actcgtctct tgctcaaggc atctgacaag gcaccatggt cagataacgg cgacgctaaa
     2761 aacccagccc tatctccact aggcgaaaac gtgaagacca aaggtcaata cttctatcaa
     2821 gtagccttgg acggaaatgt agctggcaaa gaaaaacaag cgctcattga ccagttccga
     2881 gcaaacggca ctcaaactta cagcgctaca gtcaatgtct atggtaacaa agacggtaaa
     2941 ccagacttgg acaacatcgt agcaactaaa aaagtcacta ttaagataaa tgttaaagaa
     3001 acatcagaca cagcaaatgg ttcattatca ccttctaact ctggttctgg cgtgactccg
     3061 atgaatcaca atcatgctac aggtactaca gatagcatgc ctgctgacac catgacaagt
     3121 tctaccaaca cgatggcagg tgaaaacatg gctgcttctg ctaacaagat gtctgatacg
     3181 atgatgtcag aggataaagc tatgctacca aatactggtg agactcaaac atcaatggca
     3241 agtattggtt tacttgggct tgcgcttgca ggtttactcg gtggtctagg tttgaaaaac
     3301 aaaaaagaag aaaactaatc agctaaggaa ataaatgatg gatagtgggc tgactaagat
     3361 tagtttaaca actcaatcag caatcaggac tttctttcaa tagcagatta aaatcatcgt
     3421 aaaacaataa aaatagtgtt atacttaaag cagtatagca ctgtttttat caaaggagag
     3481 acagatggga aagacaattt tactcgttga cgacgaggta gaaatcacag atattcatca
     3541 gagatactta attcaggcag gttatcaggt cttggtagcc catgatggac tggaagcgct
     3601 agagctgttc aagaaaaaac cgattgattt gattatcaca gatgtcatga tgcctcggat
     3661 ggatggttat gatttaatca gtgaggttca atacttatca ccagagcagc ctttcctatt
     3721 tattactgct aagaccagtg aacaggacaa gatttacggc ctgagcttgg gagcagatga
     3781 ttttattgct aagcctttta gcccacgtga actggttttg cgtgtccaca atattttgcg
     3841 ccgccttcat cgtgggggcg aaacagagct gatttccctt ggcaatctaa aaatgaatca
     3901 tagtagtcat gaagttcaaa taggagaaga aatgctggat ttaactgtta aatcatttga
     3961 attactgtgg attttagcta gcaatccaga gcgagttttc tccaagacag acctctatga
     4021 aaagatctgg aaagaagact acgtggatga caccaatacc ttgaatgtgc atatccatgc
     4081 tcttcgacag gagctggcaa aatatagtag tgaccaaacg cccactatta agacagtttg
     4141 ggggttggga tataagatag agaaaccgag aggacaaaca tgaaactaaa aagttatatt
     4201 ttggttggat atattatttc aaccctctta accattttgg ttgttttttg ggctgttcaa
     4261 aaaatgctga ttgcgaaagg cgagatttac tttttgcttg ggatgaccat cgttgccagc
     4321 cttgtcggtg ctgggattag tctctttctc ctattgccag tctttacgtc gttgggcaaa
     4381 ctcaaggagc atgccaagcg ggtagcggcc aaggattttc cttcaaattt ggaggttcaa
     4441 ggtcctgtag aatttcagca attagggcaa acttttaatg agatgtccca tgatttgcag
     4501 gtaagctttg attccttgga agaaagcgaa cgagaaaagg gcttgatgat tgctcagttg
     4561 tcgcatgata ttaagactcc tatcacttcg atccaagcga cggtagaagg gattttggat
     4621 gggattatca aggagtcgga gcaagctcat tatctagcaa ccattggacg ccagacggag
     4681 aggctcaata aactggttga ggagttgaat tttttgaccc taaacacagc tagaaatcag
     4741 gtggaaacta ccagtaaaga cagtattttt ctggacaagc tcttaattga gtgcatgagt
     4801 gaatttcagt ttttgattga gcaggagaga agagatgtcc acttgcaggt aatcccagag
     4861 tctgcccgga ttgagggaga ttatgctaag ctttctcgta tcttggtgaa tctggtcgat
     4921 aacgctttta aatattctgc tccaggaacc aagctggaag tggtggctaa gctggagaag
     4981 gaccagcttt caatcagtgt gaccgatgaa gggcagggca ttgccccaga ggatttggaa
     5041 aatattttca aacgccttta tcgtgtcgaa acttcgcgta acatgaagac aggtggtcat
     5101 ggattaggac ttgcgattgc gcgtgaattg gcccatcaat tgggtgggga aatcacagtc
     5161 agcagccagt acggtctagg aagtaccttt accctcgttc tcaacctctc tggtagtgaa
     5221 aataaagcct aaaacccctt tacaaatcca gctattcatg gtagaatgga ttttgtgtga
     5281 aatatcagca ggaaagcatg aagctcgtca acaggtgtct tatgataagt aaccttggct
     5341 gtttaggcga agggcatctg cacgaatcag ggctttctaa gtgactattt ccaccgaaat
     5401 attatttata tcaggaggac attcatatgt cacgttatac aggaccatct tggaaacaag
     5461 ctcgtcgcct tggcctttca cttacaggta caggtaaaga attggcacgt cgtaactacg
     5521 taccaggaca acacggacca aacaaccgtt ctaaattgtc agaatacggt ttgcaattgg
     5581 ctgaaaaaca aaaacttcgt ttcacttacg gtgtaggtga aaaacaattc cgtaacttgt
     5641 tcgtacaagc tacaaaaatc aaaggtggaa tcctaggttt caactttatg cttcttttgg
     5701 aacgtcgttt ggataatgtt gtttaccgtc ttggtctcgc gactactcgt cgtcaagctc
     5761 gtcaattcgt aaaccacggt cacatccttg ttgacgggaa acgcgttgat atcccatcat
     5821 accgcgtaac tccaggtcaa gtgatctcag ttcgtgaaaa atcattgaaa gttccagcaa
     5881 tccttgaagc agtagaagct actcttggac gtccagcatt cgtatcattc gacgctgaaa
     5941 agttggaagg ttcattgact cgcttgccag aacgcgacga aatcaaccca gaaatcaacg
     6001 aagcacttgt cgttgaattc tacaacaaga tgttgtaata ttttattgaa taagacaggc
     6061 tttgaggcct tgatattaag cactttggga cgttctccct tagtgctttt ttgatttctc
     6121 ttagtatcca gctataatcg ttgagacata actagaccga tatagtccaa agtgatatag
     6181 taaaatgaac caaaaatagt acacaatgtg gtataatct
//
LOCUS       DAVBNZ010000088         6206 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000088 DAVBNZ010000000
VERSION     DAVBNZ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6206
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.089"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(482..707)
                     /locus_tag="VQ860_002025"
                     /pseudo
     CDS             complement(482..707)
                     /locus_tag="VQ860_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1555..2427
                     /locus_tag="VQ860_002026"
     CDS             1555..2427
                     /locus_tag="VQ860_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET3120394.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="VQ860_002027"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="VQ860_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3372
                     /locus_tag="VQ860_002028"
                     /pseudo
     CDS             3060..3372
                     /locus_tag="VQ860_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3376..4092
                     /locus_tag="VQ860_002029"
     CDS             3376..4092
                     /locus_tag="VQ860_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3120395.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4222..5037)
                     /locus_tag="VQ860_002030"
     CDS             complement(4222..5037)
                     /locus_tag="VQ860_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET3120396.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5034..5939)
                     /locus_tag="VQ860_002031"
     CDS             complement(5034..5939)
                     /locus_tag="VQ860_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET3120397.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
BASE COUNT         1961 a         1073 c         1249 g         1923 t
ORIGIN      
        1 aaataagata tgtacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagtaa
       61 tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atgttaaatg cctttctcta aattcacata tcactattgt
      361 ttaacaaaat ctaatctact ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt
      481 tttaattctc cctatatagc ctgatagctt tcccgatggt acgaatatgg ttgctttcgt
      541 ctaggtggat gtcggggtat tcgggattga gtttttttga ggcagccttg gcggagtttc
      601 ttgacatagt tagtgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccataact aaatcgtcgt
      781 cctgcatcga gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct
      901 ctcggcatag gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg aggaaagagg gcatcaatca agctactgaa
     1021 tactttaact aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tctaatggtg tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctat
     1261 tatatttttc gcctctaaca atcgcaatct cttctttatc tacgaacgaa atcgctttct
     1321 atttttgtaa gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaacg cctactataa ttaaatcaag tttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagcct tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggt acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt
     1921 gggaccaact gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccagtt gcttttccta gataatgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgaggca
     2101 actacagatg tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg
     2221 tttgtaggcc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttgggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgataag ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatgtccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa
     2641 gagttacttc aacccattgg ctccgacgga gtaagttgct ttcgtggata ccaaaaacag
     2701 ccgcaatttg ttcataagtg cgatattctc gcacttattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt
     2821 ttaatacagc taacatctct ttaaaagtcg tgcgttgaac accaacaaga cgcttaaatc
     2881 gtgcatcggt tagttgttta cttgcttcat aattcataga actattatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtccca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaata ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aaacgcgaag aattgcgtca gattatcaca actatctttg aacaaaagat gaataagcat
     3361 agtattaagt agagaatgaa aaaatatttt attggcggtt tgggaagcaa tgcctatcat
     3421 agcaaggatt ttcttcaaga actagattcg caggtctatt ttctaaatcc atatgaaaag
     3481 catcttcgag atgaaacaga attgaaatca tggtttaaaa atgagattgt agaggaagaa
     3541 tctatctgtc tgataggtca ttctattgga ggcgatttag ctcgttattt cgcatcggaa
     3601 tttgaagaag taaagaaact gattcttttg gatggtggct atctagattt agataagatt
     3661 ttacctttgg atacagagtt agaggaaact aaaaattata tcaaatctca aattatttcg
     3721 gacttagatg ttcttacttc taaagaaaaa tctgaagcaa agcattggtc agaaaatatg
     3781 gagaaagctg taagacagtc ctatcactgg aatgttgagt ataatagata tgagttggct
     3841 ataaattatg aaaatataga agcgatactc cgcctacgga gaaaaataca agcttttaag
     3901 agagaagtgg gagatacctt gtttattagt cctcgctatc ctaatgaagc tacatggaga
     3961 gaggaagccc taaaagaatt gccagactat tttgatacta tttttttaga aaactttggc
     4021 catgagcttt atactcaagc acctaaagaa atcgctagtc taatgaatga gtggctcgct
     4081 tattttctat gagctacttg tattgctgga aatggtataa gatgaaaatc tacaagtcac
     4141 taattttcat ataaccaaaa aacgaacagg ctctttttct gttattcaga agagaacttg
     4201 ttcgttttta tcttgatttt cttaaaaagc tctatataca tagggatttt ctggtttatc
     4261 gactttggta aagctgtcga tttccaaggt tggaaggttt tgtttgagtt ctttatggta
     4321 gtgattgacc agttttcctt tggctgaaat ccaagtgttg ttttcatact gccgggtatt
     4381 gcccttggtc agcaatccat agacaccaga atctgcgatg cagtgaataa tgccgaagcg
     4441 gaacagaaat tggctattgg catgactggg gtcattatag acaaagcctg tgaactggat
     4501 tgtcttaccc tcaaattcat ctggatagtc gtagatagcc tccatgacct ccatatagtt
     4561 ttcattagtg atctgaatac tatcttggga taagtattta tccgccgccg ttcgcatttc
     4621 cttttcatag gctgattttg aaaaataaga actggtatct ggtttcaaat attggcttgt
     4681 cgtcccttcg cttgtctgaa tggctagatc cgttccttcc gataggggga aatgataacc
     4741 tttagcagaa acggtctgag aatccaagct aacagttggg aaagttaagc cgatgacaag
     4801 tggaatagcc agaagagaaa tactcgtcat cttggctaat cggctgttca gatgactgtg
     4861 ggttttgact tgcttcatcc agatatacaa ttgaacgata gccaagataa aagaaagcac
     4921 catggagata taggccagat aggaatagtg catgttgatg tactggttta gtttgcccga
     4981 cagatggagg taaatagtca gttcaaaata gccagctaaa actaaaaatc gaatcatagg
     5041 atgactccaa tcaagagaga atagactaag acgacaagag ttacaattgt tatgaagtga
     5101 ctgataaatc gtgctttcaa gtaatttttc atcatgagaa tatttttgat atccagcatt
     5161 ggaccaatga cgagaaaggc cagaactggt gccaaaccga aactcgagag aagagaagca
     5221 cctataaagg catccgcctc actacagagc gaaagaagaa aggctaaaat catcaagagc
     5281 aggatggcaa aaagaggggt cgcactgata gaggtcagaa tccgagtcgg aacgtagacc
     5341 tgtattatag aagcaaagag gcagccaaat accaaataac gccccgtatc aaaaaattca
     5401 tcaatggcct gcacaaagac ttgaaaaact ttttttgcag aactcaagta agaaaaatca
     5461 tgctcatgac aagccagacg attttctttc tgaatcggtt cttgccagaa aaatcctaga
     5521 aaaattccta gtattacagc cacaagaatg gaacccagag ctcgtaatag ggcgacatgg
     5581 aaggagttgc caaaggcaga ataggtcgca aaaagaacaa tgggattgat aacaggtgct
     5641 gtcacaagaa aaggaacggc cgtgtaactt ggaacctttt tttccagaaa acgattgatg
     5701 atggggacga ttccacattc acaagaaggg aaaaacatac cgacgaaggt cccaaaaaag
     5761 attctccccc aacgatttcg agggagaaaa tgataaacct tgtcaggtgt gatataaact
     5821 tcaatcagcc ctgagacaat gcttcctatc agaacgaagg gaagggcttc aatgataatg
     5881 gagagaaaaa tggctccagt ttgaagtaca ctagatggga gttgttgaaa agcagtcatc
     5941 tagtttttct tttctgcttt ggcttttttc tctttgtcat cagggaaagt aacttgtttc
     6001 aaatcaggga gtttagcaaa ctcttcaaac atcttgtcca agtcgtctcg ttttgtaaat
     6061 tttacagcca taggtgtacc tcgattctaa attctacctc tattatacta ttattttgcg
     6121 gaaaagggag ttttttaatt tgttttcgat agttgatact cttcgaaaat ctcttcaaac
     6181 cacgtcagct tcgccttacc gtagta
//
LOCUS       DAVBNZ010000089         5485 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000089 DAVBNZ010000000
VERSION     DAVBNZ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5485
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.090"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            1..1160
                     /locus_tag="VQ860_002032"
                     /pseudo
     CDS             1..1160
                     /locus_tag="VQ860_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1184..1340
                     /locus_tag="VQ860_002033"
                     /pseudo
     CDS             1184..1340
                     /locus_tag="VQ860_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1333..1506)
                     /locus_tag="VQ860_002034"
     CDS             complement(1333..1506)
                     /locus_tag="VQ860_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET3120398.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(1665..3272)
                     /locus_tag="VQ860_002035"
     CDS             complement(1665..3272)
                     /locus_tag="VQ860_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET3120399.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            3425..4909
                     /locus_tag="VQ860_002036"
     CDS             3425..4909
                     /locus_tag="VQ860_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET3120400.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            5004..>5485
                     /locus_tag="VQ860_002037"
     CDS             5004..>5485
                     /locus_tag="VQ860_002037"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET3120401.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1624 a         1239 c         1005 g         1617 t
ORIGIN      
        1 atgaagaaat atgactttca aaaaccttct aaaattcctt atcttgaaac aactggtatg
       61 cctactagaa ttctccttag aaagcgtcgc tttaagtgct atcactgttc aaaaatgatg
      121 gtcgctgaaa cttctatcgt caagaaaaat caccaaattc ctcgtattat caaccaaaaa
      181 attgcgcaaa agttaattga aaagaattct atgaccgata ttgcccatca gctggccatc
      241 tcaacttcaa ctgttattcg taagctcaat gattttcact ttaaacatga tttttcttgt
      301 cttcctgaga ttatgtcttg ggatgagtat gcttttacaa agggaaagat gagcttcatt
      361 gcgcaagatt ttaacaagct caatatcatc actgttcttg agggaagaac acaagctatc
      421 attcgaaatc actttcttcg ctacgataga gctgtccgat gtcgcgtcaa aattattact
      481 atggatatgt ttagccctta ctatgactta gctaaacagc ttcgctttca aatttctagg
      541 ctcaggctga aacagtctcc tagactgttt cactcccgaa tgctaaaatc gttcttgatc
      601 gctttcatat tgtacaacat cttagccgtg ctatgagtcg tgtgcgtgtt caaatcatga
      661 atcagtttca tcgaaaatcc catgaataca aggctatcaa gcgctactgg aagctcatac
      721 aacaggatag tcgtaaactc agcgataaac atttttatcg ccctactttt cgtatgcatt
      781 taaccaataa agagatttta aacaagcttt tgagctattc acaagacttg aaacatcact
      841 atcagctcta tcaactcttg ctgtttcact ttcagaataa ggaaccggag aaatttttcg
      901 gactcattga ggacaatctt aagcaggttc atcctatttt tcagactgtc tttaaaacct
      961 ttctaaagga caaagagaaa atagtcaacg cccttcaact accctattca aacgccaaat
     1021 tggaagcgac caataatctc atcaaactta tcaagcgcaa tgcctttggt tttcggaact
     1081 ttgaaaactt caaaaaacgg attttcatcg ctctgaacat caaaaaagaa aggacgaaat
     1141 ttgtcctttc tcaagcttag cttttcttca acccactaca gttgacaaag agcctaagct
     1201 tttacctctt cctccctact cacctgagta caatcctatt gagaaaacat gggctcatat
     1261 caaaaagcac ctcataaaag gtattaccaa gttgcaatac cttttatgag gctcttttgt
     1321 cttgttcttg tttcaattga ctatattatc agtgtaatag tctaatagat agttaaatgt
     1381 agttggattt ccactaaagg ttgatgagta agtttttgta tctgaacctg attggccgca
     1441 agcagctaaa agcaaaacag atgcaaaagt caggcctgca ctaaggacac gcttctttat
     1501 gttcatcttc tttctcctta atagtgggaa tttgtaaagt taattgaatt tcgagaatga
     1561 aagtttataa accttggtta taaaaaacaa aggatttctg ctttttatac agtcctccct
     1621 tgtttttata tgatttcaat tttaaatttt tctgcaaaaa atatttatag taattccaca
     1681 cagaaagcat cccatggaac taagatttgt ttttcaaaga cttcttgagc tagggtgttt
     1741 tcaatcaaga cagatttgac ttttccttct actgtcaagt cttgctcttc attggacaag
     1801 ttagccacaa ctaggaagcg acggtcgcca tccttacgta tataagcaaa gaccttatca
     1861 gccgtatcaa gcaattcaaa gtcagctcga actagccagc tattctcctt gcgaatttgg
     1921 accagtttct gataggtata gaaaatagaa tctggatttg ccagcgcttc ttggacattg
     1981 atcatctcgt aatttggatt aaccgccaac caaggttgac ctgttgagaa accagcgttt
     2041 ttgctctcgt cccattgcat aggggtacgg gcattgtcac gtccaataac acggatactg
     2101 tccatgattt cttcaatcgg aacacctttt tcaagagcct cacgcgcata gttgagagat
     2161 tcaatatctt ctacttgatc cagcgtttca aagggatagt tggtcatgcc aatttcctca
     2221 ccttggtaga tataaggagt tcctctcatg agatgaagca agatggcaaa ggctttggca
     2281 gatttttcgc ggtattcttg gtcatttccc cagattgaga caatacgagg gaggtcatgg
     2341 ttgttccaga agagggaatt ccagccgtcc tcaactccta actctgtctg ccatttgttg
     2401 aagatttctt ttaacttagc gatattcagc tctttttgat agtgccattt aggctgacct
     2461 tcctgatact gaagaccgat atgttcaaac tggaagacca tagacaattc ttgccccttt
     2521 ggatcagagt agagcttggc aatctctggc gttgctcccc aagtctcccc tactgtcaag
     2581 agatccttat ctccaaaggt cgcctgattc atttccttga gatagggatg gagcatagga
     2641 ccattattga ctaccttctc gtcaggaatt ttgccaatca tgtcaataac atccatacgg
     2701 aaaccaccaa tacccttatc aatccagaag ttcatcatct cataaatttt ctggcgaagt
     2761 ttttcatttt cccagttgag atccggctgt ttcttgctga aaaagtggag atagtattga
     2821 cctgactttt catcgtattc ccaagcagac ccactaaaga tagaatctag gtcattgggt
     2881 tcatcgcgcc agatatagta gtctcgctca gggctattag gattttcaca ggcctctaca
     2941 aaccaggcat gctcatccga ggtatgattg accaccaagt ccatgatgat acggatatca
     3001 cgcttcttag cttctgcaat cagttgatcc atatcctcca tggttccaaa aatcgttgca
     3061 atcgcttgat aatcagcaat atcgtagcca ttatcatcca tagggctgtc ataaacggga
     3121 gaaagccaaa ttgctgtgat tcctagcttg gctagatagt ccaacttact ggtaattcct
     3181 ggcaaatcgc caattccatc tccattacta tccataaaac tctttggata gacttgatag
     3241 actacggcat tgtgccacca tttttcttgc atcttcttac ctcattattt tcataatcta
     3301 tagtctatga tagcactttt taaaattttg tgcaagcgtt tgcttaatct ttttaatttc
     3361 ttttttagct ccgtagtttc ctaacttcca attttttatt ataatagagt ccagaggtaa
     3421 aaaaatgaaa aaacaagctt ttagttctga acaatatttg aatttacaac gcgaccatat
     3481 tttggagcgc attaaccaat ttgacggcaa gctctactta gagtttggcg gtaaaatgtt
     3541 agaagatttc cacgctgctc gtgtccttcc tggttatgaa cctgacaaca aaatcaagct
     3601 cttgcaagaa ttgaaagagc aggttgaggt tgtgattgcc attaatgcta gcaacattga
     3661 acattccaaa gcacgtggcg acttaggcat ttcttatgac caagaagttc ttcgtttgat
     3721 tgacaaattc aatgaattag ggatttttgt tggttccgtt gtcattacac aatacgctgg
     3781 ccaacccgct gcagatgcct tccgcaatca acttgagaaa aacggaattg attcttatct
     3841 tcattatcca atcaaaggat atccgacgga tatggatcac atcatttccc cagaaggcat
     3901 gggcaaaaac gactacatca aaaccagtcg caacttgatt gtcgtaaccg ctcctggacc
     3961 cggttctgga aaattggcaa cgtgtatgtc caatatgtac cacgaccaaa tcaatggcat
     4021 caagtctggc tacgctaaat ttgaaacctt ccctgtttgg aatcttcccc ttcatcaccc
     4081 agttaacttg gcttatgaag ctgccacagc tgaccttgat gatgtcaaca tgattgaccc
     4141 cttccatctt caaacctatg gagaaaccac tgtcaactac aaccgtgata tcgaaatctt
     4201 cccagtgctc aagcgcatgt tggaacgtat tctcggaaaa tcaccatacg cttcaccgac
     4261 agatatgggt gtcaacatgg ttggtttcgc tattacagat gacgaggctg ctgtcgaagc
     4321 ttctaaacaa gaaatcatcc gccgttacta tcaaacagtt cttgacttca aagctgaaaa
     4381 agttggcgaa gctgccgtca agaaaattga gttactcatg aacgacctcg gtatcacacc
     4441 tgcagaccgt aaggttgctg tcgttgcgcg ccaaaaagca gaagaaactg gtggaccagc
     4501 cctagccttt gaattgccaa atggggaaat catcactggt aagaactcag aactctttgg
     4561 ccctacagcc gctgccttga tcaatgccat caaaaaatca gctgacatcg ctaaagaagt
     4621 aaaactaatc gagcctgaag ttgttaagcc aatccaaggt cttaaaatcg atcatctcgg
     4681 tagccgcaat ccacgccttc attcaaatga aatcctgatt gcacttgcta tcacagctac
     4741 agaaaatcct gatgctgccc gcgctatgga agaactcggc aacctcaaag gaagcgaagc
     4801 ccactcaacc atcatcttga ctgatgaaga caagaatgtc cttcgtaaac tgggtatcaa
     4861 cgtaaccttt gacccatact accaatacga ccgcttatat cgtaagtaaa gatttcaacc
     4921 tctccagcct cggagaggtt ttctctctgt ctcaggagca acctttatga tataatgaga
     4981 gaagaaaact gaaaggattt accatgtcaa aagaagttat tgtcgaaagt tttgaacttg
     5041 accacaccat tgtcaaagca ccctatgttc gcttgattgg ggaagaaaca ggaccaaaag
     5101 gagacatcat ctccaattat gatattcgct tggtgcaacc aaacgaagac tctatcccta
     5161 ctgccggcct tcacactatc gagcacctct tagccaaact catccgtacc cgcattgacg
     5221 gcatgattga ctgttcacca tttggttgcc gcacaggctt ccacatgatt atgtggggac
     5281 gtcacaccag tgctaaaatc gcagctgtta tcaaggattc gctcaaggaa atcgctgaaa
     5341 ctactacttg ggaagatgtc ccagggacaa ccatcgaatc ttgcggaaac tacaaggacc
     5401 acagcctctt ctctgctaaa gaatgggcaa aactcatctt ggaacaaggg atttcagatg
     5461 atgcctttga acgtcatgtg attta
//
LOCUS       DAVBNZ010000090         5000 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000090 DAVBNZ010000000
VERSION     DAVBNZ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5000
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.091"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            302..1847
                     /locus_tag="VQ860_002038"
     rRNA            302..1847
                     /locus_tag="VQ860_002038"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1899..1971
                     /locus_tag="VQ860_002039"
     tRNA            1899..1971
                     /locus_tag="VQ860_002039"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1932..1934,aa:Ala,seq:tgc)
     gene            2096..4997
                     /locus_tag="VQ860_002040"
     rRNA            2096..4997
                     /locus_tag="VQ860_002040"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1410 a         1019 c         1468 g         1103 t
ORIGIN      
        1 acaccgcctt ttcacggcgg taacacgggt tcgaatcccg tacggactat ggtatgttgc
       61 ggttggaaca cttgatgaaa aaaagtttaa aaaagcttaa aaatcttcaa aaaagtgttg
      121 acaagcgaaa gcggctgtga tatactaata tagttgtcgc ttgagagaag cgagtgacaa
      181 agacctttga aaactgaaca agacgaacca atgtgcaggg cgctacaaca taagttgtag
      241 tactgaacaa tgaaaaaaac aataaatctg tcagtgacag aaatgagtga gaactcaaac
      301 ttttaatgag agtttgatcc tggctcagga cgaacgctgg cggcgtgcct aatacatgca
      361 agtagaacgc tgaaggagga gcttgcttct ctggatgagt tgcgaacggg tgagtaacgc
      421 gtaggtaacc tgcctggtag cgggggataa ctattggaaa cgatagctaa taccgcataa
      481 gagtagatgt tgcatgacat ttgcttaaaa ggtgcacttg catcactacc agatggacct
      541 gcgttgtatt agctagttgg tggggtaacg gctcaccaag gcgacgatac atagccgacc
      601 tgagagggtg atcggccaca ctgggactga gacacggccc agactcctac gggaggcagc
      661 agtagggaat cttcggcaat ggacggaagt ctgaccgagc aacgccgcgt gagtgaagaa
      721 ggttttcgga tcgtaaagct ctgttgtaag agaagaacga gtgtgagagt ggaaagttca
      781 cactgtgacg gtatcttacc agaaagggac ggctaactac gtgccagcag ccgcggtaat
      841 acgtaggtcc cgagcgttgt ccggatttat tgggcgtaaa gcgagcgcag gcggttagat
      901 aagtctgaag ttaaaggctg tggcttaacc atagtaggct ttggaaactg tttaacttga
      961 gtgcaagagg ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga
     1021 acaccggtgg cgaaagcggc tctctggctt gtaactgacg ctgaggctcg aaagcgtggg
     1081 gagcaaacag gattagatac cctggtagtc cacgctgtaa acgatgagtg ctaggtgtta
     1141 gaccctttcc ggggtttagt gccgtagcta acgcattaag cactccgcct ggggagtacg
     1201 accgcaaggt tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg
     1261 tttaattcga agcaacgcga agaaccttac caggtcttga catccctctg acgactctag
     1321 agatagagtt ttccttcggg acagaggtga caggtggtgc atggttgtcg tcagctcgtg
     1381 tcgtgagatg ttgggttaag tcccgcaacg agcgcaaccc ctattgttag ttgccatcat
     1441 ttagttgggc actctagcga gactgccggt aataaaccgg aggaaggtgg ggatgacgtc
     1501 aaatcatcat gccccttatg acctgggcta cacacgtgct acaatggctg gtacaacgag
     1561 tcgcaagccg gtgacggcaa gctaatctct taaagccagt ctcagttcgg attgtaggct
     1621 gcaactcgcc tacatgaagt cggaatcgct agtaatcgcg gatcagcacg ccgcggtgaa
     1681 tacgttcccg ggccttgtac acaccgcccg tcacaccacg agagtttgta acacccgaag
     1741 tcggtgaggt aaccgtaagg agccagccgc ctaaggtggg atagatgatt ggggtgaagt
     1801 cgtaacaagg tagccgtatc ggaaggtgcg gctggatcac ctcctttcta aggataagga
     1861 actgcgcatt ggtcttgttt agtcttgaga ggtcttgtgg ggccttagct cagctgggag
     1921 agcgcctgct ttgcacgcag gaggtcagcg gttcgatccc gctaggctcc attggtgaga
     1981 gatcaccaag taatgcacat tgaaaattga atatctatat caaatagtaa caagaaaata
     2041 aaccgaaaac gctgtagtat taataagagt ttatgactga aaggtcagaa aataaggtta
     2101 agttaataag ggcgcacggt ggatgccttg gcactaggag ccgacgaagg acgtgacaaa
     2161 cgacgatatg ccttgggtag ctgtaagtaa gcgatgatcc atggatttcc gaatggggga
     2221 acccaacagg taatacctgt tacccacatc tgttaaggat gtgaggagga agacgcagtg
     2281 aactgaaaca tctaagtagc tgcaggaaga gaaagcaaaa gcgattgcct tagtagcggc
     2341 gagcgaaacg gcagaagggc aaaccgaaga gtttactctt cggggttgta ggactgcaat
     2401 gtggactcaa agattataga agaatgattt gggaagatca gccaaagaga gtaatagcct
     2461 cgtatttaaa atagtctttg tacctagcag tatcctgagt acggcgggac acgtgaaatc
     2521 ccgtcggaat ctgggaggac catctcccaa ccctaaatac tccctagtga ccgatagtga
     2581 accagtaccg tgagggaaag gtgaaaagca ccccgggagg ggagtgaaat agaacctgaa
     2641 accgtgtgcc tacaacaagt tcgagcccgt taatgggtga gagcgtgcct tttgtagaat
     2701 gaaccggcga gttacgttat gatgcgaggt taagttgaag agacggagcc gtagggaaac
     2761 cgagtctgaa tagggcgcct tagtatcatg acgtagaccc gaaaccatgt gacctaccca
     2821 tgagcaggtt gaaggtgcgg taagacgcac tggaggaccg aaccagggca cgttgaaaag
     2881 tgcttggatg acttgtgggt agcggagaaa ttccaaacga acttggagat agctggttct
     2941 ctccgaaata gctttagggc tagcgtcgac attagagatt cttggaggta gagcactgtt
     3001 tgggtgaggg gtccatcccg gattaccaat ctcagataaa ctccgaatgc caatgaatta
     3061 tggtcggcag tcagactgcg agtgctaaga tccgtagtcg aaagggaaac agcccagacc
     3121 accagctaag gtcccaaaat aattgttaag tggaaaagga tgtggggttg cacagacaac
     3181 taggatgtta gcttagaagc agctattcat tcaaagagtg cgtaatagct cactagtcga
     3241 gtgaccctgc gccgaaaatg taccggggct aaaacaattt accgaagctg tggatacctt
     3301 tataggtatg gtaggagagc gttctatgtg tgatgaaggt ataccgtgag gagtgctgga
     3361 acgcatagaa gtgagaatgc cggtatgagt agcgaaagac aggtgagaat cctgtccacc
     3421 gtaagactaa ggtttccagg ggaaggctcg tccgccctgg gttagtcggg acctaaggag
     3481 agaccgaaag gtgtatccga tggacaacag gttgatattc ctgtactaga gtatgtagtg
     3541 atggagggac gcagtaggct aactaaagca gacgattgga agagtctgtc taagcagtga
     3601 ggtgtgaatt gagtcaaatg cttaattcta taacattgag ctgtgatggg gagcgaagtt
     3661 tagtagcgaa gttagtgacg tcacactgcc aagaaaagct tctagcgttt aaacatactc
     3721 tacccgtacc gcaaaccgac acaggtagtc gaggcgagta gcctcaggtg agcgagagaa
     3781 ctctcgttaa ggaactcggc aaaatgaccc cgtaacttcg ggagaagggg tgctgacttt
     3841 aagtcagccg cagtgaatag gcccaagcaa ctgtttatca aaaacacagc tctctgctaa
     3901 atcgtaagat gatgtatagg gggtgacgcc tgcccggtgc tggaaggtta agaggagtgc
     3961 ttagcgtaag cgaaggtatg aattgaagcc ccagtaaacg gcggccgtaa ctataacggt
     4021 cctaaggtag cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg cgtaatgatt
     4081 tgggcactgt ctcaacgaga gactcggtga aattttagta cctgtgaaga tgcaggttac
     4141 ccgcgacagg acggaaagac cccatggagc tttactgcag tttgatattg agtgtctgta
     4201 ccacatgtac aggataggta ggagtctaag agatcgggac gccagtttcg aaggagacgc
     4261 tgttgggata ctacccttgt gttatggcca ctctaaccca gataggtgat ccctatcgga
     4321 gacagtgtct gacgggcagt ttgactgggg cggtcgcctc ctaaaaggta acggaggcgc
     4381 ccaaaggttc cctcagaatg gttggaaatc attcgcagag tgtaaaggta taagggagct
     4441 tgactgcgag agctacaact cgagcaggga cgaaagtcgg gcttagtgat ccggtggttc
     4501 cgtatggaag ggccatcgct caacggataa aagctaccct ggggataaca ggcttatctc
     4561 ccccaagagt tcacatcgac ggggaggttt ggcacctcga tgtcggctcg tcgcatcctg
     4621 gggctgtagt cggtcccaag ggttgggctg ttcgcccatt aaagcggcac gcgagctggg
     4681 ttcagaacgt cgtgagacag ttcggtccct atccgtcgcg ggcgtaggaa atttgagagg
     4741 atctgctcct agtacgagag gaccagagtg gacttaccgc tggtgtacca gttgtcttgc
     4801 caaaggcatc gctgggtagc tatgtaggga agggataaac gctgaaagca tctaagtgtg
     4861 aaacccacct caagatgaga tttcccatga ttatatatca gtaagagccc tgagagatga
     4921 tcaggtagat aggttagaag tggaagtgtg gcgacacatg tagcggacta atactaatag
     4981 ctcgaggact tatccaaagt
//
LOCUS       DAVBNZ010000091         4770 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000091 DAVBNZ010000000
VERSION     DAVBNZ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4770
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.092"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..447
                     /locus_tag="VQ860_002041"
     CDS             <1..447
                     /locus_tag="VQ860_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3120402.1"
                     /translation="SIALRKQLANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNYSHD
                     MKLFKMSCRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKACNHALSK
                     ERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(436..1083)
                     /locus_tag="VQ860_002042"
     CDS             complement(436..1083)
                     /locus_tag="VQ860_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3120403.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(1192..1710)
                     /locus_tag="VQ860_002043"
     CDS             complement(1192..1710)
                     /locus_tag="VQ860_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET3120404.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1937..2806)
                     /gene="rsmI"
                     /locus_tag="VQ860_002044"
     CDS             complement(1937..2806)
                     /gene="rsmI"
                     /locus_tag="VQ860_002044"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET3120405.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESSHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2809..3126)
                     /gene="yabA"
                     /locus_tag="VQ860_002045"
     CDS             complement(2809..3126)
                     /gene="yabA"
                     /locus_tag="VQ860_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET3120406.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(3166..4056)
                     /locus_tag="VQ860_002046"
     CDS             complement(3166..4056)
                     /locus_tag="VQ860_002046"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET3120407.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(4053..4691)
                     /locus_tag="VQ860_002047"
     CDS             complement(4053..4691)
                     /locus_tag="VQ860_002047"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET3120408.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
BASE COUNT         1348 a         1069 c          788 g         1565 t
ORIGIN      
        1 tcaatcgccc taagaaaaca attagcgaat cattctggta aaaagaaatt tcacgctatg
       61 aaggctcaag cgattgtcac aagtcaaggg agaattgttt ctttggatat cgctgtgaac
      121 tatagtcatg atatgaagtt gttcaaaatg agttgtagaa atatcggaca agctggtaaa
      181 atcttggccg acagtggtta tcaagggctc atgaagatat atcctcaagc acaaactcca
      241 cgtaaatcca gcaaactcaa gccgctaaca gctgaagata aagcctgtaa ccatgcgcta
      301 tctaaggaga gaagcaaggt tgagaacatc tttgccaaag taaaaacgtt taaaatgttt
      361 tcaacaacct atcgaaatca tcgtaaacgc ttcggattac gaatgaattt gattgctggt
      421 attatcaatc atgaactagg attctagttt tgcaggaagt ctaatgtaat tctcaagctg
      481 tgagttcatt atgatttgta aatccgatat atcttcagca gctaaaaaca cattttgaaa
      541 tgttccaagt ccgttttcac caaaactata ttctctctta ctatacttac tcttattatt
      601 ctctatatag ttagagtcaa ggttcttaac ctcttgaagt tcattttctt tacttctgag
      661 gttaaaatct tttacttctg aagttaagtt ttttgacttc tgtaagtcat tttcttttac
      721 ctgaaatata ctcataaagt ctttaacata aatgatgttc ggcttaccaa gtccaagcct
      781 tactctttcg atcagtccta ttcctttttt tacatcaagc tcatctaatg tttttatggc
      841 agttggcttt gagatatttc ttcttttcat aatttcttcg acagtaaaat agataaatac
      901 tctgccttcc ttgtctatcc agttattctt aaatgacatt cctgtctgtt taagaagtat
      961 ggaataaagg ataattgctt ctgctgataa gccccgaaat tcttctctat caactaatat
     1021 ctccggtact tttaagaagt taaatctttc cgcttctctg ttataaaaat attcaaagtc
     1081 catgcaagat cacctccctt cttaaaaatt tgcaaagaaa aagacgatag tttttcttct
     1141 atcgcctttg gtaaccattt ttatgaaatt ttttaaagtt aaaaatataa tttataatac
     1201 tatcttcttc cattttctga ttttagttct gaaagttcca aaaggtgcaa ccgtatttac
     1261 atgaataaac ttatacactt cccaagtcgc tgttttagtc gcttcatcag cccactttct
     1321 catatgcggt tcaaataatt cttcctcact caacgaatca atcattgcag agatagaatt
     1381 aatattttca tttaattttg ctttcaactc ttgcagagat aaatgagcgt aggtatctgt
     1441 gaaccactga tataattcac caagttgatt ccatttaaat ttatccgatg gtgtttttac
     1501 ttgaagcccc tttctttcat cttcttccca tttaagaacc aagttggtcc aaccaacctg
     1561 ataagcaagg ttttctgctg gagttctgtc aacttcatca gctctcttat cttttaaatt
     1621 ttctggaata ttatcaaatt ctaaaatata tttctcaaat gttttctcta tctcagcttt
     1681 tagttcttct ttattttcgt atgttcgcaa aaaatcacct tctttctgat ttatcaatcc
     1741 tttgatttaa aatgacctta tttttctatt tataccttct aagaacgcta taactgctgc
     1801 tccaaccatc ggtattccgt atgggcttaa taaaaaactt aataccaaag cttctatacc
     1861 aagtgataca tctttatatt accatcacta attaagttaa acagaaacag acagaattat
     1921 tacattctgt ctccctttat tgtttttctt cccaatcgtg gtaggcagcg tagagttgac
     1981 tcttattcca ctggtaaatc ttagctactt ccttaatagc ttgatttttc ttcatgcctt
     2041 gctggatacg ggcttggatt tctaagaaca agtcctcctc gtctttttcc tccacatcct
     2101 gactggcacc ttcaacaata agaaggcatt cgcccttgag tggcgtttca gcgatgcttt
     2161 ccagcaattc agaaatggta cctctttggt attcttcata gattttagtc aattccctga
     2221 ccaagactac cgagcggtca ccgtagactt ctagcatatt ttccaatgta tctgccacac
     2281 gatgggacga ttcataaaaa atctgagttt caggatagtc ttttttcgag tcgaaaaatt
     2341 gcttttgctg acctgatttt ctcggtaaaa agccgtaaaa gatatgtggc tgcggcgcta
     2401 aaccactggc aatcaaggca gaaattcctg cagaggcacc tggaacagtc acaactgcaa
     2461 tttcttcctc aatagctgcc ttaaccaaat catgaccagg gtctgaaatg ctaggcaaac
     2521 cggcatcaga gacctgagca atactttgcc ctgctttcaa gaaaccaatc aaatcaggaa
     2581 ttttttcctt ggcattgtgc tcatgaaaac tgatctgctt ggtggaaatg tcaaaatgct
     2641 tgagcaaaag acctgtattg cgcgtatcct cagcagcaat ccagtccact tctttcaagg
     2701 tctggatagc gcgaaaagtc atatcatcta gattgccaat cggcgttgcc actagataca
     2761 gcttgccata gggagactgc cccttaaaac ttttttgaat ttgcatgcct actccctgta
     2821 taacaactca tcacagaaca tacattcttc gtcctgctct cgacgttgtc cataaaaatc
     2881 attacatacg tgaaatccat cacggtaaat acgacggaca ctttcgcgaa catgcttggc
     2941 cttgacggga gcgtctgctt ccacctcacc caagcgttct cgcaacttac tattttccaa
     3001 gcgaagagct gtattttcct ctaccaggct cttgagattt ttcttgatgg cttccacatc
     3061 ggccaaggtt accaataatt gttgggaaaa atcatccagc gcgtcaaata attctttttt
     3121 gtccataaaa cagctctttc ctttctttat cattcatttt tgagtttata tttctttcaa
     3181 gaccagatat tccatggcat tttgaaagct gacattagct tgccacattt ttctagcttc
     3241 tagtaaatct tgtagaatca ctcttactct tacctgcaag aggtcctgcc cacagagaac
     3301 ttcaagaatc cgtaaaacct gatcctgttt ttccttatca tctgccaagt tggctaattt
     3361 ggcaacctgt agataacttt cttttttctt agctactaac caagtcagca ggcgttcact
     3421 ttcatcgacc aaggtccaaa aacttgcctg attagccaac ttttctgctt cagctcgcga
     3481 ttgactaaac ttagctaaaa gagtcgcttt tttcttaaca agtcccattt gttctaagag
     3541 taagataagt ttttcttctt gctttttaaa gtggaagatc tgggtccgac ttcggattgt
     3601 cggtaacatc ttttcctcat cgctagtcaa gaagaaaata taaacttcac tctggggttc
     3661 ttcgatgacc ttgagcagag aattggctgc gttgggatgc attttatccg cttgctcgat
     3721 gataaagacc tgttgctggc tttcaatccc tgcttgagaa aactgtccca ccaattccct
     3781 aatgcgttct gtcttgatga cctgattgac tggcttaatc aaggtgacat cgggaaattc
     3841 tccctgttca atcagcttgc aacttcggca tttctcacat ggtaagacgc caactttatc
     3901 cgtacaaaag aggctcttag ctaaaaattg cgctatttcc aagcttccaa agaaacctga
     3961 aaagagatag gcgtgattga gctggtcttg ttctaagata cggacaaaac ggtcaaactg
     4021 agctggttgc caagccttta gttgatcttg tttcatttgg ccaagcccat tccgtcaaac
     4081 aagacagcct tggtagtttc cacaacttgc tccaaaggga gactagcatc aatcttgaca
     4141 atgcgatttc cctctttatc cagaagagaa aggtagcctt gacgaacttt tttatgcaag
     4201 tccaaccctt ccaaatccaa acgattaacc tcgcggtcac tattagcagc aatacgagcc
     4261 agcccttctt ccacctcgat gtcaaaatag agtgtcaaat cgggtttgag gccatctgtc
     4321 gcaaactgat tgagccagtc aatggcttca atatctaagc cacgaccaaa tccctgatag
     4381 gcaacagaac tatcgataaa acgatccatg atgaccaact tgccagcttc aagggctgga
     4441 agaacttttt ccaccaaatg ctgtctgcga ctggcaatat agagaagtag ctctgtttta
     4501 gcatccatct gagtatgact tggatccaaa atcacttccc gaatcttctc cccaatcaag
     4561 actccgccag gttcacgggt cgtcagcacc tttactcctt tttcctctaa aattggtagc
     4621 agagcctcta aaacactggt cttgcctgct ccctctggtc cctcaagaga gactaaaaat
     4681 ccttttgaca tgtctaactc atttcttttt tactacttct attctatcaa aaaaataggg
     4741 gtttgtgaca atctttttgt cttctcattt
//
LOCUS       DAVBNZ010000092         4667 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000092 DAVBNZ010000000
VERSION     DAVBNZ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.093"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(92..529)
                     /locus_tag="VQ860_002048"
     CDS             complement(92..529)
                     /locus_tag="VQ860_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET3120409.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLKAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(614..3247)
                     /gene="polA"
                     /locus_tag="VQ860_002049"
     CDS             complement(614..3247)
                     /gene="polA"
                     /locus_tag="VQ860_002049"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET3120410.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3503..3853
                     /locus_tag="VQ860_002050"
     CDS             3503..3853
                     /locus_tag="VQ860_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3120411.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4068..4172
                     /locus_tag="VQ860_002051"
     CDS             4068..4172
                     /locus_tag="VQ860_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3120412.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGG"
     gene            4177..4410
                     /locus_tag="VQ860_002052"
     CDS             4177..4410
                     /locus_tag="VQ860_002052"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120413.1"
                     /translation="MFSQLRMREEQALLAQDYALETARAGGIEQGLERGKVEGREERK
                     LFAFLDIVRQDLLTSEVASQQLGMSVSEFEALL"
     gene            4537..>4667
                     /locus_tag="VQ860_002053"
     CDS             4537..>4667
                     /locus_tag="VQ860_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET3120414.1"
                     /translation="MEQLHFITKLLDIKDPNVQILNIINKDTHKEIIAKLDYDAPSCP
                     "
BASE COUNT         1426 a         1114 c          860 g         1267 t
ORIGIN      
        1 gtgttttgag cagcccgcgg ctagtttcct agtttgctct ttgattttca ttgagtataa
       61 cacaaaaggt agcccatcag ctaccttttt cttatgcttc ctcaatcaag cgagtatgtt
      121 ctctcttgat acagcgattc atcacgatat catcacatcc accatcacgc aaaatctctt
      181 tcgcttttaa actttcaagt cctagctgtg cccaaaaaat cttggcatca gctttgagaa
      241 aatcacgcgc cacatcgggc agaaattcac tgcgacgata aacattgaca atatctacag
      301 gaaaaggaat ttcagcgagg ctagcataag ccttttcacc caagatttcg ccacctgccg
      361 ccttgggatt gactgggatg attttatagc cccgagcctg catttccttt gtcactcgat
      421 tgctggttgt ttcttcacgg tcagacaaac ccaccacagc aagggtttta ctcgttgcga
      481 gatactgacg aatcacgcca tcacttggat tgataaattc ttgactcata gaaaacctcc
      541 tttttcatca gtatagcaca ttttgaaaag gtttgcagaa ttctactaca aaaaaggagg
      601 actagccccc tttttattta gcctcgtacc aggttgcccc ttcattctca tctgcgataa
      661 gaggaacact gagttgaatg gcttcttcca tggtttgttt caccaatttt ttcatctcta
      721 ccaattcaga tttaggcact tcaaggacga tttcatcgtg cacttgtaac agcatcttag
      781 tctgataacc acctgcaacc aaggctttat ccagctgaat catggcaatc ttgagaatat
      841 ctgctgccga accctggata ggtgagttga tagcagttcg ctccgcaaaa ccacgaatat
      901 tgaagttgcg cgaattgata tctggcaact cacggcgacg cttaaagagg gtctctacat
      961 agcccttatc acgcgcctcc cgcaccactt catccatgta gtttttaata cctggaaaac
     1021 gttcaaagta ggtatcaatg taggctttgg cttccttacg actaattccc aaattattag
     1081 acaagccaaa gtctgaaatc ccataaacca ctccaaagtt aactgccttg gcattgcgac
     1141 gatcatttgc agtcacatta tcaggacgct caatgccaaa gacccgcatg gctgtcgaag
     1201 tatggatatc tgccccctct tggaaggcct taatcaagtg ctcatcctta gaaatatgcg
     1261 ccaaaacgcg caattcaatc tgtgaatagt cagagctgag tagcacacta tcctcccact
     1321 ctggcacaaa agccttccga atcaagcgcc cttgttccaa tcgggcagga atattttgca
     1381 agtttggatc cacactagac aaacgcccgg tctgggtcaa atcctgcata tagcgagtat
     1441 gaatctttcc atcagccaaa atccagtcct gcaagccaat tacataagta gattgaatct
     1501 tagcaatttg acggtaatcc aggattttct taacaatcgg agcaatagga gcgagacgct
     1561 ccaacacatc cactgctgtc gaataacctg tcttggtttt cttagtgtat tctagaggaa
     1621 gtcccaattt ctcaaagaga agcacgccca actgcttagg cgagttgaca ttaaactcct
     1681 caccagccag ctcgtaaatc tcttgagtca gtttttcaat gacaagctca ttttcagcct
     1741 gcatctcaag caaggtctct ttcttgacca taatcccagc aatttccatc ttggcaagga
     1801 caaaagccag aggttgctcc atatcataaa gaagctctaa ttgcccattt tcgctgagtt
     1861 tttcaagtaa aataggctct gtttctacca aaacagcaag tttacaagct aagtgttcca
     1921 agaatttctc acgttcagga atggcctttt taacaccctt accgtagaaa gtttcatcat
     1981 caaccaagta agtctgacca taaagactag cgatggtcgc aatttcattg tcctccacag
     2041 tcgaaaggag gtatttagcc aaacggatgt caaaagcagg cgcctgcaaa tccacaccaa
     2101 aacgttgcaa aagaacttta accttcttaa agtcataaac tctcagagat gttttttcta
     2161 agaaatcctt gaaaatcggg tcttgcaaca gctcaagctt gtctgtggca tagagcttat
     2221 ccccacaaga ccaggcaaat ccaaccaaat tatccgtatg gtaattctca ccaaaaagct
     2281 caaagtggaa gatagactct tcactcagca tatcttgact gatttggtca acaatagtaa
     2341 aatccaaact ctcagacaca tcagctgacg acacatttaa agcctgcttt agctgtttga
     2401 agcccatctc atcgtagaat ttcccaagat tttcaacatc tggaccacta tagaccaagt
     2461 cctctaaacc aatcgcaatc ggtgccttgg tatcaatggt cgctagtgtt ttagataaaa
     2521 aggcctgttc cttgtcattg atgagatttt ccttcatctt agaagtcttc attccatcaa
     2581 tattttcata aatcccctca agcgaaccat gctccagcaa gagcttaata cccgtctttt
     2641 caccgacttt ggtcacccca gggatattat ccgacttatc acccatgagc gccttgagat
     2701 cgataaactg agctggtgtg aggcccattt cttccatgag gtaatctggc gtaaaggcct
     2761 caaactcagc cacacctttc ttggaaattt caaccaccgt atgctcatcc gtcagctgaa
     2821 tcaaatcctt gtccccactg acaatggtaa tatcaaaacc atcctgctct gctagcttat
     2881 ccagcgtccc aatgatgtca tccgcctcat actgagccag ctcatagtga cgaatcccca
     2941 tatgatccag caactcacga atgaaaggaa attgctcacg aaactcatca ggagtcttgg
     3001 cccgaccacc cttatagtcc gcatacatct ctgtccggaa ggtcgtcttt cccgcatcaa
     3061 aagccaccaa aatatgactc ggctcaaccc gctccaacaa atgactcaac atcaactgaa
     3121 aaccataaat cgcattggta tgcaaaccag ccgcattctt aaaacggtcc aactgctgat
     3181 acagcgcaaa aaacgcccga aaagctacag aagacccatc aatcaataat aattttttct
     3241 tatccataca cccattataa aggaaagaat caaaaaatac cattgggaag agctagagca
     3301 agtatttttc aaactttttc cgaataaata gatagagcca gagaatttag taaacctaga
     3361 tttaaaaatg tgctataata tagtatattg aatctataat agtacacctt gactgctaaa
     3421 atatttctat aaattaattt gactttcctg atagagttat tcacatctta tttcaactca
     3481 ctatagaagg aggaatagga ggattctcag acatccgggc atcagcccaa ctaatgattt
     3541 gattgctaag aaaatattca gcaatccaga aatcacttgt caatttattc gcgatatgct
     3601 ggacttgcca gcaaaaaatg tgaccatttt ggagggaagc gatattcacg tattactctc
     3661 catgccttac tcggtgcagg atttttatac cagtatagac gtcttggcgg agttggataa
     3721 cggtactcaa gtaattattg agattcaagt ccatcatcag aattttttca tcaatcactt
     3781 gtgggcttac ctgtgcagtc aggttaatca aaatcttgaa aaaattcgtc agcgagaagg
     3841 tgatactcac tagatctaca aacacatcgc tcctgtttac gtcattgcta tcgtggatag
     3901 taattatttc tcagatgacc tggcttttca tagctttagt atgcgcgaag acacaacagg
     3961 tgaggtattg gcgattacca acaatggaca ggaaaaccat ctggttaaga tggcattctt
     4021 ggaattaaaa aatacagaga aaccagcaaa gacaaggttc gcaagccatg gttggagttt
     4081 ttcggcaaca agccctttac ccagcaaccg caacgagcca ttacccaagc aaatcaactg
     4141 ctggactaca agagctggtc cgaggaggat aggaaaatgt ttagtcaact acgtatgcga
     4201 gaagaacaag ccttgttagc gcaggactat gccttggaaa ctgctagggc gggaggtatt
     4261 gaacaaggct tagagcgtgg gaaagttgaa ggaagggaag aaaggaaact ttttgccttc
     4321 ctagacatag tacgccaaga tcttctgact tctgaggttg ccagccagca attaggtatg
     4381 tcagtatctg aatttgaggc actgttgtaa aatggctcca taatatccat agtgggtaaa
     4441 tcccctatgg atattatgga gcctattttg tgtagaaaaa aagtcccata tgacctataa
     4501 tgaaaagcga caaaacaact cattagaaag aatcatatgg aacaattaca ttttatcaca
     4561 aaattactag acattaaaga ccctaatgtc cagattttaa acatcatcaa taaggataca
     4621 cacaaggaaa tcatcgccaa actggactac gacgccccat cttgccc
//
LOCUS       DAVBNZ010000093         4529 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000093 DAVBNZ010000000
VERSION     DAVBNZ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.094"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..281
                     /locus_tag="VQ860_002054"
     CDS             <1..281
                     /locus_tag="VQ860_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3120415.1"
                     /translation="NGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTW
                     YYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            682..1803
                     /gene="mnmA"
                     /locus_tag="VQ860_002055"
     CDS             682..1803
                     /gene="mnmA"
                     /locus_tag="VQ860_002055"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET3120416.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1944..2399
                     /locus_tag="VQ860_002056"
     CDS             1944..2399
                     /locus_tag="VQ860_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3120417.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2409..4322
                     /gene="mnmG"
                     /locus_tag="VQ860_002057"
     CDS             2409..4322
                     /gene="mnmG"
                     /locus_tag="VQ860_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET3120418.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
BASE COUNT         1308 a          919 c         1105 g         1197 t
ORIGIN      
        1 acaacggttc atggtactac ctaaacgcta acggtgctat ggcaacaggt tgggctaaag
       61 tcaacggttc atggtactac ctcaacgcta acggttcaat ggcaacaggt tgggtgaaag
      121 atggagatac ctggtactat cttgaagcat caggtgctat gaaagcaagc caatggttca
      181 aagtatcaga taaatggtac tatgtcaatg gcttaggtgc ccttgcagtc aacacaactg
      241 tagatggcta tgaagtcaat gccaatggtg aatgggttta agccgattaa attaaatcat
      301 gttaagaaca tttgacattt taattttgaa acaaagataa ggttcgattg aataaattta
      361 tgttcgtatt ctttaggtac ctatcttatg atttcaggaa atgtcattaa aaaaacgact
      421 ccttttctct aacttgaaaa atagattaga gaaaatgggt tgttttattt attatagtta
      481 tttgaatgaa gataagaaga aggtatactc acatcattca cataatctgt atattgacta
      541 taagttttaa aaaacaattt ttaagctctt ccttgtcttc tctaaccaag cgtgttataa
      601 tgaatactgc tcaagcgacc ttcaatcgtg aagcacacac gaccttcaat cgtgaataaa
      661 cgaatagatg ggagacttac catgagtgat aactctaaaa cacgtgttgt cgtggggatg
      721 agtggtggtg ttgattcgtc ggtgacggct cttttgctca aggagcaggg ctacgatgtg
      781 atcggtatct tcatgaagaa ctgggatgac acagatgaaa acggcgtctg tacggcgacc
      841 gaagattaca aggatgtggt tgcggtggca gaccagattg gcattcccta ctactctgtc
      901 aattttgaaa aagagtactg ggaccgcgtt tttgagtatt tcctagcgga ataccgtgca
      961 gggcgcacgc caaatccgga cgttatgtgc aacaaggaaa tcaagttcaa ggcctttttg
     1021 gactatgcca tgaccttggg ggcagactat gtagcgactg ggcattatgc tcgagtggcg
     1081 cgtgatgagg acggcactgt tcacatgctt cgtggcgtgg acaatggcaa ggaccagacc
     1141 tatttcctca gccaactttc gcaagaacaa cttcaaaaaa ccatgttccc actaggacat
     1201 ttggaaaagc ctgaagttcg aaaactagca gaagaagcag gcctttcgac tgctaagaag
     1261 aaagactcga cagggatttg ctttatcgga gaaaagaact ttaaaaactt cctcagcaac
     1321 tacctgccag ctcagcctgg tcgcatgatg actgtggatg gtcgcgatat gggcgagcat
     1381 gcaggtctga tgtattatac aatcggtcag cgtggcggac tcggtatcgg tgggcaacac
     1441 ggcggtgaca atgccccttg gttcgttgtc ggaaaagatc taagcaagaa tattctctat
     1501 gtaggacaag gattctacca tgattcgctc atgtcaacta gcctagaagc cagtcaagtc
     1561 cactttactc gtgaaatgcc agaagagttt acgctagaat gtacggctaa attccgttac
     1621 cgtcagcctg actctaaggt gaccgtccat gtcaaaggag acaaggcaga ggtcatcttt
     1681 gcggaaccac aacgcgcgat tacaccaggc caggcagttg tcttttacga tggcgaagag
     1741 tgtctaggtg gtggtttgat tgacaatgct taccgcgatg gacaagtttg tcagtacatt
     1801 tagattgaca aattttctca atttgctaca ataataacag caatagaaat gatggtcaaa
     1861 gctcatggat gttgcaggct tttttgtcct gcacttcttt ggagttttga ctgtttttgt
     1921 gtcgtttaag ggaaaggaca agaatgactc aacaagactt tcggacaaaa gtagacaata
     1981 cggtttttgg tgttcgggcg acagctttga ttcttcaaaa tcacaagctt ctagtcacca
     2041 aagacaaggg caagtattac actatcggcg gtgcgattca agtcaatgaa agcacggaag
     2101 acgcggtagt ccgtgaagtg aaggaagaac tgggtgtcaa agctcaagct gggcagctag
     2161 cttttgtggt tgaaaatcgt tttgaacagg acggtgtttc ctatcacaat atcgagtttc
     2221 attatctggt ggacttactt gaggatgccc cattgaccat gcaggaagat gagaaaaggc
     2281 agccctgtga gtggattgac ttggataagc ttgaggatat ccagctagtt ccagcctttt
     2341 taaaaacggc cctaccagat tgggaaggcc aactaagaca cattcatctt gaggaatagg
     2401 agagaaacat gacttatcat tttactgaag aatacgatat tattgtaatt ggtgcgggac
     2461 acgctggggt tgaggcttcc ttggccgcta gccgtatggg ctgtaaggtc ctgcttgcga
     2521 ccatcaatat tgaaatgctg gctttcatgc cttgtaatcc ctctatcggt ggttctgcta
     2581 aggggattgt cgtacgtgaa gtcgatgccc tcggtggcga gatggccaag accattgaca
     2641 agacttacat ccagatgaag atgctcaaca cagggaaggg cccagccgtt cgtgcccttc
     2701 gtgcgcaggc tgataaggaa ctttactcta aggaaatgcg caagacagtt gaaaatcaag
     2761 aaaatctgac ccttcgtcaa accatgattg atgagatttt ggtggaagat ggcaaggttg
     2821 tcggtgtgcg tacagccacc catcaagaat atgctgctaa ggctgttatt gtgacgacag
     2881 ggactgctct ccgtggggaa attatcatcg gagacctcaa gtactcatca ggtcctaacc
     2941 acagcttggc ttctattaac ctagctgaca atctcaagga actgggtctc gaaatcggtc
     3001 gtttcaagac aggaacccct ccacgtgtca aggcttcttc tatcaattac gatgtgacgg
     3061 aaattcagcc aggagacgaa gtgcctaatc atttctcata cacttcacgt gatgaggatt
     3121 atgtcaaaga tcaagtgcca tgctggttga cctataccaa tggtaccagt catgagatta
     3181 tccaaaacaa cctccaccgt gcgcctatgt ttacaggtgt ggtcaaggga gtggggcctc
     3241 gttactgtcc gtcgattgaa gacaagattg tgcgctttgc ggacaaggaa cgtcaccaac
     3301 tcttccttga gccagaaggg cgcaatactg aggaagtcta tgttcaagga ctttcaacca
     3361 gtctgcctga ggatgtccag cgtgacttgg ttcattccat caaaggtttg gaaaatgcag
     3421 agatgatgcg gacaggttat gctattgagt atgatatggt cttgcctcat cagttgcgtg
     3481 cgactttgga aaccaagaaa atctcaggtc tcttcactgc tggtcagaca aatggaacat
     3541 caggttatga agaagctgct ggccaaggga ttatcgcggg tatcaatgcg gctctgaaaa
     3601 tccaaggtaa acctgagttg attctaaaac gaagtgacgg ttatatcggg gtgatgatcg
     3661 acgacttggt gaccaaggga accattgaac cttaccgtct cttgaccagt cgtgctgaat
     3721 accgtctcat tcttcgtcat gacaatgctg atatgcgctt gactgagatg ggacgcgaga
     3781 ttggccttgt ggatgatgaa cgctgggctc gttttgaaat caagaaaaat caatttgata
     3841 atgagatgaa acgcctagac agtatcaaac tcaagccagt caaggaaacc aatgctaagg
     3901 ttgaggaaat gggcttcaag ccgttgacag atgcggtgac agccaaagaa ttccttcgcc
     3961 gtccagaagt ttcttaccaa gatgtggtgg ccttcatcgg accagctgca gaagacttgg
     4021 atgacaagat tatcgaattg attgaaacag aaatcaagta cgaaggctat atttcaaaag
     4081 ccatggatca ggttgccaag atgaaacgta tggaagaaaa acgcattcca gccaatattg
     4141 actgggatga catcgattct attgcgacgg aagctcgtca gaagttcaaa ctcatcaatc
     4201 cagaaaccat cggccaagcc agccgtattt cgggagtaaa cccagcagat atttctattt
     4261 tgatggtgta tctggaaggt aaaaatcgta gtatttctaa aactcttcaa aaatcaaaat
     4321 gatacgtcgt cggcttctta cgaatgagtt caaagcttgg ctttgattca tctccagcct
     4381 cccatagttc cccgaactat gggagctaac tcaagttatg cattttccta gccttctggt
     4441 ctgattttca ttgagtttta atctcaaaag aaagcataga gaaaaacagc tccgaagacg
     4501 gagctgtttt gttgacttgt actcaatga
//
LOCUS       DAVBNZ010000094         4347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000094 DAVBNZ010000000
VERSION     DAVBNZ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.095"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(60..659)
                     /locus_tag="VQ860_002058"
     CDS             complement(60..659)
                     /locus_tag="VQ860_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3120419.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTHPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(661..1758)
                     /locus_tag="VQ860_002059"
     CDS             complement(661..1758)
                     /locus_tag="VQ860_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3120420.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLVYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(1758..2495)
                     /locus_tag="VQ860_002060"
     CDS             complement(1758..2495)
                     /locus_tag="VQ860_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3120421.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(2497..3381)
                     /locus_tag="VQ860_002061"
     CDS             complement(2497..3381)
                     /locus_tag="VQ860_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3120422.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(3368..3562)
                     /locus_tag="VQ860_002062"
     CDS             complement(3368..3562)
                     /locus_tag="VQ860_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120423.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLCQFIRGALEFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(3559..3765)
                     /locus_tag="VQ860_002063"
     CDS             complement(3559..3765)
                     /locus_tag="VQ860_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120424.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1421 a          963 c          701 g         1262 t
ORIGIN      
        1 tattgttcca ttcactaccg tcaattttag cacatagtct tcatgaaaat attatatcat
       61 cataaccaac cagattcttt tgcgatatta gctgcctctg ttcgattacc agcatccagt
      121 tttgaaagaa tattggtgac atagtttcga atagttccgt ttgagaggta aagctgatct
      181 gcgatttctt ggttggataa gccccgggcg attcccttta aaacagcaat ctcttgttct
      241 gtcaacggat taggatgcgt catcaccact tccatcaatt caggcgaata ctccttgcgc
      301 ccttcgagga cggtgtgcaa ggtttgcatg aggtctgcaa tgcttctttc tttcaagaca
      361 taagcatcca ctccagcctt gaccgcacgt tcaaaatacc ctggacgctt gaaggtcgtc
      421 accacaacca cctttgtttc aagcctttct gatcgtatcc actccaagac ttcaagacct
      481 gtcttaacag gcatttctac gtcaaggatg gcgatatcta cagactcctt ttctaatagt
      541 tggattgctt cttgcccatt cttggcttga aggacagact ccacatctgg ttgaagcgtg
      601 agcaattgac acatggcatc tcgcaacata ctttgatctt ctgcgactaa tactttcatc
      661 ttagtttctc tccttataag gtagtcgaac ttgcacttcc gttggatgtt tctgactgat
      721 tacacttact tctcctgaaa atggaaaaac acgatctcgg actgtatgga gctcatctcc
      781 ttttagaaaa gcaaagccgc agccatcatc acttactgtt aaaatgagtt ccttctctgt
      841 ccgttctaat tttaagtaag ctttagacgc tttggcatgt ttgatgatat tggtcaccaa
      901 ctcaagcaaa atcatagaag ccattgactc cacatcctgg gtcaagctag ccttgtctaa
      961 gtgattctca acttgaacct caattccagc aatttctaac atctttttca cagtctctag
     1021 ttcggatgtc aaagttctag acttaagatt ttccacaatg gttcgcactt cattcatgga
     1081 atccttgctg atctggtgaa tttcttttaa ttccttttcc acctgtggat aagcctccat
     1141 ctgaaataac tgcaaggcta gatcagtttt aacactaagc atagcaaagg tatgccccag
     1201 actatcatgc aaatcttgac cgatacgatt gcgttcattt tcagcaagca atagatttat
     1261 ctgggcattt tgcttaacct gtgcttcttt caaatcctcc acaattcgaa tccgaaccaa
     1321 gccaaaagtc attaaatcga caaaagcaag aattacaagt agatagacta gaaactcaac
     1381 ttcgattctc tgaaaaatca acagttgacc cacaacaagg acttgagcaa gaagaaaagt
     1441 ccagacatgt aaagacttta aaccacctac gctgaaatga tagcttaaga gattggatag
     1501 gaaaaagaaa aaccagatat aattaacagc cacaaaggca gtattcccaa ctacataagt
     1561 cagcaggatg ccccaatata gccaagatag acgctggctc ttagttgtta aaacacccaa
     1621 atacgccact acaaatagaa tatcaatcaa taaatgccag gcagaaagcc acccagtcac
     1681 tacaggtagg atggggaaaa ccataaaaat taaactgatc caaaacatat aatgtatgct
     1741 tttcagtctt tcaagcatta agcattctcc ttatgacctt gaaggtaaat ggtcaaacca
     1801 aacaaaacta ctgaaaaaac aagtaaataa actgtggctg atagattgat gccaccctca
     1861 tttaagaagg tcttgagcaa ctccatcaac tgataggtcg ggagacactt acctactact
     1921 tgcatccagt ctggaaataa agaaatgggc atccagagtc cgcctaaaac agccaatcct
     1981 agataaagaa gattgcccac aacagacatc agctgactag ttggtaagag agtcaaggtc
     2041 aagccaagtg ctacaaaagc aatactcccc acaatcagca aaatcgcagc tccaacccat
     2101 tttactagag gcatgtctac acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt
     2161 gagaccaaat aatcaaccag catacttgtt atctttgata gataatattc taccatattt
     2221 acagggctat gacgcaatgt tttctgccag ttgttcatct tatcggtatg taaaacagct
     2281 ggaaatgaga ggatagttgt cgacatcatg gaaaaggcag tcatggagat gaggtaatca
     2341 cgcataaaat tcgcgagttc acctggtgtg tcctgataga taccagaaaa aaataaatag
     2401 aaagccgtcg gcatccctac cgacaataga taatagatta attgtcgttt ggtcaataaa
     2461 aattctatct tactaagtgc tatccatcgt ttcatcttag ttatctccct tctgcgtctc
     2521 ttcaaagatt gtattcaaca aactacgatt attaacttcg atttcttgca tcctacatcc
     2581 tgcttgggct aatagttccc agaaagcatc tgcttctcga gtgactactt gtaaagaatc
     2641 ttgctttagg gtccagtttt caaccaaatt tgactgctct acgacttcct tgtaagctat
     2701 aggaaggata aagtgctttt ctatttcctc gctacgcata gctagaggcg tcgtatctcg
     2761 aatcaactct cccttattta agagcaaaat gcggtctgca gtgtgttcca cttcctcaat
     2821 ataatgggac gaatagagaa tggtgactcc ttgcgctttt aactcctgga caatttccca
     2881 aaaacgttga cgagttgagg tatccatgga cgcagtaggc tcatctaaaa aaacaatctt
     2941 tggtcgccca attaaggtca agacgaaaga aaagagacgc ttttgaccgc ctgataattt
     3001 ttctgccaac tgttcttttt gttgcttgac aaactgcaat agttgatcaa tttcctgatt
     3061 gctcaaagga tttggataga tacgttgaaa gaaagcaatc aactctttaa cttttaattt
     3121 ctgaacgatt acattttctt gagggaggta agccctagta tagtctaact tagaactcgt
     3181 cactggtaaa ccttgaatag atacttgacc gcttgtgacc agtttatctc caagcaaaca
     3241 atctaagagt gttgtctttc cggcaccatt tggaccaatt aaggcaacac attcaccatc
     3301 gttgatttca aaggagatgt tccgcaaaat ttccttgtct tttattttct tactcaattt
     3361 ctcaacttta accaccgtca tgagactctc ctttcaacca ctccattccc atagggaaaa
     3421 cgacgaaaat cataaatcca aactccaaag caccacgaat gaattggcaa agcaaggctt
     3481 gatcaaacca atcagtaaac atttccacta accataccaa gagtgacagg ccgataaaga
     3541 aatagatgat ccctctcttc attcttcaaa ctcctttttc acatctctga ctaatttcaa
     3601 accttctcta acaagccaag acatgattcc aaagccagca aagaccttcc aaggaaaatg
     3661 gtagaaatcc tcatccaatc ccgaaaacat gagataggtc ataactcctg ctactactaa
     3721 actcattgca ataatcattt tatttctcat ctcttcttcc cccatttcat actacaatta
     3781 tagtctttta aaatcagagg aggcagaagc ttctgtcact agaaaatatg acaaatgtca
     3841 taaaaaattc tgttcaaaac aagcaagata cattatacaa taaaacacaa tcagaaaaat
     3901 ctaaggcaac ttcctcaaaa gagatatcaa actcaattca caccataatg taaactaata
     3961 cttatttaaa atcaaaaaga gtagaaattt ttatcagaca aacacatata tagtgtattg
     4021 aatctataac agtaggcctt aaatactaaa atatttctat aaattaattt aactttcctg
     4081 atagagctgt tcatatctta tttcaattct ctatattata cgttgaacaa aacccttcta
     4141 ttgctttctt aaaaatttat aagagttata aaatctgtta aatttcaatg tgtataccta
     4201 aactacggta tttattgaaa agactggaga caaaaagtat acgctgccaa aatgaattac
     4261 tgaaaatcaa aaaagagaga accaaactga ttccctctta atgtatataa tatctagttt
     4321 taaaaataca cactcacata tctctgt
//
LOCUS       DAVBNZ010000095         4193 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000095 DAVBNZ010000000
VERSION     DAVBNZ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.096"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            720..1712
                     /locus_tag="VQ860_002064"
     CDS             720..1712
                     /locus_tag="VQ860_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3120425.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINKEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VQ860_002065"
     CDS             1714..2532
                     /locus_tag="VQ860_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET3120426.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VQ860_002066"
     CDS             2534..3319
                     /locus_tag="VQ860_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3120427.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3358..3636
                     /locus_tag="VQ860_002067"
     CDS             3358..3636
                     /locus_tag="VQ860_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET3120428.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3621..3818
                     /locus_tag="VQ860_002068"
     CDS             3621..3818
                     /locus_tag="VQ860_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3120429.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1171 a          717 c          904 g         1401 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gagtgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aattttacaa tccataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccagaaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaataa agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctatc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagaa acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaagg cagttgtagc tgaggttttg
     3421 aaggatttgc cagaatggtt tggaatccca gaaagcacac aagcctatat agaaggaacc
     3481 acgacactgc aagtttggac cgcctatcag gagagtgatt tgactggatt tgtaagctta
     3541 tcctattcga gtgaagattg tgcagagatt gattgtctcg gcgtaaaaaa gcttatcaag
     3601 gtagaaaaat tgggagccaa ttgcttgcta ctttagagag tgaagctcgt aaaaaagttg
     3661 gttatctgca ggtcaaaaca gtagcagaag gttctaataa agattatgat cgaacaaatg
     3721 acttttatcg aggtcttggc tttaaaaagt tagagatttt tcctcaacta tggaatccgc
     3781 aaaatccttg tcagattttg attaaaaagc ttgaataata ttatttgaca tctattctca
     3841 gagtgctata ctgtaagtgt aatcgccgat ttagctcagt tggtagagca aggcactcgt
     3901 aaagcctagg ttataggtag ataaacgact gaggatttga aaaaatagat aggtagaaga
     3961 taaccgttaa gccttattct tagcggttat ttatattgtt taatagcgct gatatttcat
     4021 caattatgcc tgttttcgtg tttctggtag ttgttcaagt ttattgctac tatttttgat
     4081 ggtatgaatg tgcttataat gtatcccggt taacgaaagt tttggactta tactcttaga
     4141 aaatctcttc aaaccacgtc aacgtcgcct tgccgtgcgt atggttactg act
//
LOCUS       DAVBNZ010000096         3984 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000096 DAVBNZ010000000
VERSION     DAVBNZ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3984
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.097"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(382..915)
                     /locus_tag="VQ860_002069"
     CDS             complement(382..915)
                     /locus_tag="VQ860_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET3120430.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1004..1780)
                     /gene="recX"
                     /locus_tag="VQ860_002070"
     CDS             complement(1004..1780)
                     /gene="recX"
                     /locus_tag="VQ860_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET3120431.1"
                     /translation="MKITKLEKKKRLYLMELDGQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            complement(1790..2566)
                     /locus_tag="VQ860_002071"
     CDS             complement(1790..2566)
                     /locus_tag="VQ860_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HET3120432.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQETKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2623..3978
                     /gene="rlmD"
                     /locus_tag="VQ860_002072"
     CDS             2623..3978
                     /gene="rlmD"
                     /locus_tag="VQ860_002072"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3120433.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKENHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1266 a          698 c          745 g         1275 t
ORIGIN      
        1 atttcatttt actatactat tacgaaatta gatatataaa tgaaaacttg cctcaaggta
       61 ggtttttttg ctagtagaaa agcgatagac agaaattgtt ggactcttaa aaaaatgaag
      121 ttttgctcaa aagagcttct taaattaaaa cgagcaatta tcagttcaaa tctgtttcaa
      181 aagaagaacg gataaattaa tcgatgcttt gtttttgagt taggaagtta agcatgccaa
      241 actgagtcgt aggaataaat ctctttctag taatgtgttg taactctgct ataatggatt
      301 tattcctttt tgtgtttaca caatttattt tatactacca aaaaaacaag gtcaggattt
      361 tgttcctgac ctttgacaac tttaccgatt ctttagttct acatagcgct tgtaccaaat
      421 gtttacatag gcttctgaga aaggaccacg tccattgtta atccaatcaa caagaatttt
      481 gacatgttct tttaaaatat agtccaagtc atcagaataa ttcattttgc gtttgtgacg
      541 ctcgtactct tcaacgtcca agagacgttt ttccccatct gtaaaaattt taacatccaa
      601 atcgtaatca atatacttca gtgcttcttc atccagatag taggggctag ccatattgca
      661 atagtaagaa gttccattat cacgaatcat ggcaatgata ttaaaccaat atttcttgtg
      721 aaagtaaaca atagccggtt ctcgagtgac ccaacgacga ccatcacttt cggtaacaag
      781 tgtatgatcg ttgacaccaa taatggcgtt ttctgttgtt tttagtacca tggtgtcccg
      841 ccaagttcgg tggagactcc catcatgctt ataactttga attgtaataa agtcgccttc
      901 ttttggaagc ttcataacta accaactttc tacaatttat aagtttatca tttactattg
      961 taccataaaa ttacctaaaa tctgtgaatt tcacttggaa atattaaaga tattctctaa
     1021 gagcgcttgc tatatccgaa aaatcgtagc cctttcgtgc taaaacttga gttaaacgct
     1081 gcttcagttc gtatccttca tactttcgag catacttact atattgttta tcaagttcct
     1141 tgaagatgag ttcttgagtc gtttcttggt caacttggct atctaagtcg tcaaaggcaa
     1201 ttttagcatc agaataagag aagcccttgt tagtcaagtt ctggataatc ttatcttgca
     1261 gggcacgaga tggaagtttt ccctcatatt ttttcaatag tttattagct acacgttgag
     1321 caacttcaga aaaatcaaat tctttcaagt tctcttctat agtagatttt gaaatccctt
     1381 tttgagctag tttctgagtc agcacataag gacccttgtc tcctgaaagt tgattggtat
     1441 tgatgatagc ataagcgtac tgaccatcat taatccactt atcttcttta agattagcaa
     1501 taacttgaga aacgatgttt ttatcaatat cgtatttttt cagatattct ctgacttctt
     1561 tttcagtgcg tgctttaaag gataagtggt agagagcgag attcttacca taagaaaact
     1621 gggcaaaatc ctgaatctcg gtcagttcct ctttactaat gaccttatct cgagacagca
     1681 taaaacggac aatggtatct tccgtgatat aagaggtttg ctgtccatct agttccatca
     1741 agtagagacg ttttttcttt tcaagttttg tgattttcat aatttccttt catctaaatg
     1801 cttcgaaagc tgcaacaagt cgtagtttat ccatatttac atattctcta ccgtaatagt
     1861 cgagaaataa ttcagcatac gtagcatctt gtaggttgta atgaagggac caaattgccc
     1921 aaaagaggtc gatatgtcgg tcactaaaac cagccaatcc caagtcaata aagcaagaaa
     1981 aatgagaggc atccttcaag atgaaatttg gcaggcaggc atctccatga ataaaagcat
     2041 cagctttgag aatgtaacct ttctcttgta tcagttggta agcttcttca cgactgtgaa
     2101 tgtgaaattg aggcagaaga gtcttgttat aaaaagtccc cttctgatag ttttttaagg
     2161 ctttttcttt ataacgcttc agatgatttt ccgacggaaa agattgtggt ttaagactgt
     2221 gaagtttgtt taatgcttga gccagggttt gacagagtct ttcgggttga tttaaaaaag
     2281 cgagagcgtt gctgccaatg gcttctttag tcagaaggaa gtccttattt gctgataaat
     2341 aggtaatcac tggagttccc aatccttcag tttcgaacca acttgcaatc ttagtttctt
     2401 gagctaatct gcctttttga tctattttta aatagtaacc tgaatctata tataggacag
     2461 ttgcacttga atgagaagaa ctatcagaga gattagctcc cttgatatag cttcgtaatt
     2521 gttcagggaa atctagtata ctaaagcgag gtgtttttga attcatgctt ttattgtaac
     2581 atattcttaa atatcttaga aactccatgg tataatagac atatgaatct gaaagtgaaa
     2641 caaaaaatac cattaaaaat caagcgcatg ggaattaacg gtgagggaat cggcttttac
     2701 caaaaaacat tagtctttgt accaggagct ctcaaaggcg aagatatcta ttgtcagatt
     2761 acttctatta gacgcaactt tgttgaagca aaattactga aggtcaacaa gaagtctaaa
     2821 tttcgaattg tgccatcttg tactatttat aatgaatgcg gaggctgcca aatcatgcac
     2881 ctgcattatg ataagcagct ggagttcaag acggacttac ttcatcaagc gctgaaaaaa
     2941 tttgctcctg caggatatga aaattatgaa attcgtccaa ctattggaat gcaggaacca
     3001 aaatattaca gagctaagtt acaatttcag actcgaaaat ttaaaaatca ggtcaaggcg
     3061 ggcttatatg cacaaaactc tcactattta gtagagttga aagactgcct ggtacaagat
     3121 aaggaaaccc aagtgattgc taatcgctta gcagaattac ttacttatca ccagattcca
     3181 atcacggatg agagaaaagt tctaggtgtc cgtactatta tggtccgacg cgcgagaaag
     3241 accggacagg ttcagattat tattgttaca aaccgccagc ttaatttaac tcaattggta
     3301 aaagagttgg ttaaagattt cccagaagtt gtgacagtag ctgttaatac aaatacagct
     3361 aaaaccagtg agatatatgg tgaaaagaca gagattatct gggggcaaga gagtattcaa
     3421 gaaggtgtac tcaattatga attttcacta tcccctcgag ctttttatca actaaatcct
     3481 gagcaaacag aagtcctcta tagcgaagca gtaaaagcgc tggatgttga taaagaaaac
     3541 catttgattg acgcttattg tggagttgga acgattggat ttgcctttgc aaagaaagta
     3601 aaaacactca gaggtatgga tattattcca gaagctattg aagatgccaa gcgaaatgct
     3661 aaaagaatgg gatttgacaa tactcattat gaagctggaa cggcagaaga gattattcct
     3721 cgttggtaca aggaaggcta ccgagcagat gctttgattg ttgacccacc acgtacaggt
     3781 ctggatgata agttattaga tactattctt acttatgtac cagaaaaaat ggtttatatt
     3841 tcttgtaatg tttcgacctt ggctcgtgat ttggtacgct tagtagaagt ctatgatctt
     3901 cattatatcc agtcggtcga tatgttccca catacagctc gaactgaagc tgttgtaaaa
     3961 ttaataaaaa aagtttaaaa aagg
//
LOCUS       DAVBNZ010000097         3597 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000097 DAVBNZ010000000
VERSION     DAVBNZ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3597
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.098"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..152
                     /locus_tag="VQ860_002073"
     CDS             <1..152
                     /locus_tag="VQ860_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET3120434.1"
                     /translation="FPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEK
                     DESIK"
     gene            136..585
                     /locus_tag="VQ860_002074"
     CDS             136..585
                     /locus_tag="VQ860_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120435.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQLFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDHQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLWKVSHD"
     gene            578..958
                     /locus_tag="VQ860_002075"
     CDS             578..958
                     /locus_tag="VQ860_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120436.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQKYGIEVTPHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELCIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSS"
     gene            971..1204
                     /locus_tag="VQ860_002076"
                     /pseudo
     CDS             971..1204
                     /locus_tag="VQ860_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            1207..1794
                     /locus_tag="VQ860_002077"
     CDS             1207..1794
                     /locus_tag="VQ860_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3120437.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYCASLIS
                     FLWMYGQRKQVVKVNMKTRMKWLGIGFVSLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGIFLGMVRYKSDLWGSMGLHLVWNLSVYVLFFL"
     gene            1924..2514
                     /locus_tag="VQ860_002078"
     CDS             1924..2514
                     /locus_tag="VQ860_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET3120438.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVTEGKIDA
                     EEKGLYRLPDIYLDEWFVIQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEIERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNQIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            2514..3350
                     /locus_tag="VQ860_002079"
     CDS             2514..3350
                     /locus_tag="VQ860_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET3120439.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIDIFEEILCSKTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AKKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQVIREIMQQ
                     IF"
BASE COUNT         1244 a          526 c          659 g         1168 t
ORIGIN      
        1 gctttcctga ttgggctttt gaagctgcta gaaaagtctc tagtaatagt cagctctata
       61 aacaagctgg taatagtgta accgttcctg tgattgccgc aatcgcaaag aaattaaaag
      121 aaatagagga aaaagatgaa agcattaaat aaagaatcaa tactagattg tgatgaatta
      181 gaaacagaat tacatgatgc agaaatcaaa cagctggatg aacaattatt tttgatgccc
      241 aattatccat gtgagtttga agtaacattt ttagatgatt accataaaaa acacaactac
      301 ccactatttt acgagtccta tcttcaaaac gttatggaat tccttgaaag tcaagacata
      361 aagaatgggg ttgatgcctt tgtagatgat catcaaaatc tcgtttttgt tttatatgga
      421 caaggctatc gagcagaggg aaaagaggga atacttacaa ctcaagtaac tgtaaaagct
      481 tatgatgaag acaagaaacc gattaacttc gcaaatttat tagattcctt aatcgtctca
      541 gaatatcaaa tggaaccgaa tctttggaag gtctcccatg attgatctct atctaagtaa
      601 aaatagccaa agaaatcaac ttcttttgga tttctttcaa aagtatggca tagaggtcac
      661 tcctcattct atttctgaaa tgacaaagga caaattaatt gaaatgatga gctattcttc
      721 agattgtttt gagtttctat ctcccaattt attacgattt aagaaccgtg acaatctaag
      781 attaacggat ttcattgaaa tgatattaaa aaatcctgaa ctatgcatca ggcttcctct
      841 tgcggtttca aataagagag tttatccaaa tctgaatttg gaagaggcta gagctctatt
      901 gccaagagat acgaaacaat tgatttacat ggcacaaaca cattatttat ctagttaaag
      961 gagaagcaat atggctgaac gattttggga gaacttgtcc attattttgg ctgaaagaaa
     1021 tattagctga attgagttaa ccagaaaaat gtttgcggga gagtttcact atccaagtga
     1081 attgaatcgt ttgtatcaaa agatacgcca ctacaagatg gaacaacgaa tgcctcaaag
     1141 tccatgggta gaaaggattg tgcaggtatt agatttagat tatgaagatt tatttcggag
     1201 gtaactatga aaagaataat tccagtttat atattccaac aagtaaatgt cttattggta
     1261 tccctatact tactgaaatt gctttgtatt ggtgagttaa ccatactaca gattctctat
     1321 tgtgcgtcgc tcatttcttt tttatggatg tatggtcaac gaaaacaagt ggtcaaggtc
     1381 aatatgaaaa ctaggatgaa atggcttggt attggattcg ttagcctact gattataagc
     1441 ctatgtttta gtctgattca tgctcaagga accacgaatc aagcaaactt aattggcctt
     1501 caacatcagg ttccttggtt ttcattttta ttgttcttaa tcaatgcgag tatggttgaa
     1561 gaatttctgt atcgagaaat tttatggaac ttggtcagaa aattagatat tcgagttgct
     1621 ttgacaagtg ttttatttgc cttagtacat catccaggaa ccattctagc ttggtgttta
     1681 tatgtttcac ttgggatctt tttagggatg gtgcgctata aatcggactt atggggaagt
     1741 atgggtctac atttggtgtg gaacctatca gtctatgtct tattttttct ttaataatag
     1801 ctggtctgtc ttacgtatgg attaattttg aaataaaaaa actaaatgaa ttgattttaa
     1861 agaaataaaa tgctaacata tatagaagat gttagcattt tatttctaag aaaggagaat
     1921 ggtatggttg ataaaagaga gaaactgatg aactctttca atcagtatgg ttttttaact
     1981 tttaaacaag taatagatga aaatttacac tacaaaacct tattaaaaat ggttacagaa
     2041 ggaaaaatcg atgctgaaga aaaagggtta tatcgcttac ctgatattta tttagatgag
     2101 tggtttgtca ttcagtatcg atttccaaaa ggaatctttt ctttggagac agcactttgg
     2161 ttacatggtt tatctttgac tatccctttt aacatgacaa tgagttttcc ttatggtacg
     2221 aataccaaaa acattaagga agcagatata tgtcctatta tcttacgctc tcactatagt
     2281 gaaggaatta ttgaaataga gcgtcttcct ggtcaattta ttaaagttta tgaaattgaa
     2341 cgagttttgg ttgaatgtct aagaccagtt catcaggtgg atcttcaaat tattgcacca
     2401 gcgtttaaga aatattttca acagaatcaa attcatttac acaaattatt ttattatgcc
     2461 caactattta aagtaactga taagttacaa tcttatacgg aggtgctatc ttaatgtttt
     2521 caaatgcgaa tagctttaaa gcaaaaatca aaaatatttc aaaagataag ggaattccag
     2581 ctcaacaagt acaacaacat tatttaattg agcaagtgtt aaagctgatt tctactagtt
     2641 cttatagaga ttccttcatt gtaaaaggag ggtatctaat aggtcaaatg attggactag
     2701 ataagcgaac cacaatggat ttagatgtca ctctgaaggg aaccgaaatg agcagagaaa
     2761 atttgattga tatctttgaa gagattcttt gttctaaaac tgatggtttt tcattttcag
     2821 tagataagct agaacctatt cgccaagatg atgaatatgg aggattttca ttaaaattaa
     2881 atgcaacttt tgatacatta aaggaggttg tttttattga tattactact ggtgataaga
     2941 tcacaccaag agaaattact tattcaatga cttctatctt tactaatgaa agcatcaaga
     3001 tatggacata taatctagaa actgtacttg ctgaaaagtt agaaacaatc attagtaggg
     3061 gattagcttc aacacgccca cgtgatcgat atgatctttt caccttgtat aaacttagaa
     3121 aagaagagat taatcttgaa gtattaaaaa atgcacttga aaatacagca aaaaaacgta
     3181 aaagtaaaga tactatttat aattgggaag aacaagtgag aggaattgaa atttctgatt
     3241 atcagaaaga gctatggatt cgttatcaac gccaatttaa gtatgctaaa gatatctcat
     3301 ttgataactc tgttcaggtt attagggaaa ttatgcaaca aatattttag tacaaaagta
     3361 actcattcgt aaagcagtga gttgcttttt ttattccaac aacctcaaac atgtgataaa
     3421 aatttcaact actcttatct ataataaagc tacctgttct ttgaaaattg aatccactcc
     3481 gtcttgatta gcgtgcctgt gtaagtaggg aatgagagta tttccctgtg aagggcaact
     3541 ggcacaagac gtgtgtgaga attttctaac agacacggag tttatcgttt ccagact
//
LOCUS       DAVBNZ010000098         2909 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000098 DAVBNZ010000000
VERSION     DAVBNZ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2909
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.099"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(64..1005)
                     /locus_tag="VQ860_002080"
     CDS             complement(64..1005)
                     /locus_tag="VQ860_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3120440.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ860_002081"
     CDS             complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ860_002081"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET3120441.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRNLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EGTAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          846 a          688 c          578 g          797 t
ORIGIN      
        1 aaccatatat acggtaaggc gacgctgacg tggtttgaag agattttcga agagtattaa
       61 tcactaatta tctatctcaa caaatcttcc tagaatatga acattttccg agacagagac
      121 aaaggagctt ggatccactt gtgtcataat ctgtttaaat tcattaaact ctgcacgtgt
      181 aatgacagtg attaaaactg cctttctctc gtgattatag gttccttctg catcatggat
      241 catggttgct ccgcggtgca attttttatg gattttttca attaccttct ctggatgatt
      301 tgtcacaatc atggcctgca tacgcttttg cttagtaaag actgcgtctg tcacacgact
      361 agagacaaag atggtaatca tagaataaag agcgtatttc caaccaaagg tcaaacctgc
      421 tatcagcatg atagttccat ttaccaagaa agaaatacta ccgacattct tacccgtttt
      481 cttgcgaata gtcaggctga cgatatccgt cccaccactg gagatattgt ttcgaagagc
      541 aaaaccaatc cccaaaccca taacaacacc cccaaaaagg gcattgataa tgggatcctc
      601 cgtcaaggtt gccacaggga caaactggat aaagaaggaa ctcatagata ccgtgataaa
      661 ggtaaagacg gtgaacttat ggccaatctg ataccaagct aagaccatca aagggaagtt
      721 aatggcgtaa aagcttagcg aaatcggaat atgaaaacca aaccagtgat tactcaaggc
      781 agagataatc tgtgccagac ctgttgcacc actcgaatac acatgccctg gttggaaaaa
      841 gaaattaact gctactgctg ataaaaaacc atagaccaga gaggccgaaa tcttctcatc
      901 atacttttct cgagagatac tttgtaagac acgtaaaatt tttatctgat aagcaaagcg
      961 gcgcagataa tagcgccacc gcttaattcg ttttgtttgt ttcatcttct tctacttgta
     1021 agctgagttc ctctagttgt ttgagagcga ctgttgatgg agcttgtgtc attgggtcag
     1081 ttgccttgtt gttcttagga aaggcaatga cttcacggat attttcttct ccagcaagca
     1141 acatgacaaa acggtcaagc ccgatagcca aaccaccgtg tggtgggaaa ccatagtcca
     1201 tggcttcaag aaggaaacca aactggtcat tggcttcttc agttgagaaa ccaagagcct
     1261 tgaacatgcg ttcttgaagg tctttttggt tgatacgaag gctaccacca ccaagctcat
     1321 aaccgttcaa gacgatatcg taagcaatgg cacgaacctt agccaaatca ccttctaatt
     1381 cgtgagcagt cccttcctgt ggaagtgtga atggatggtg ggcgctcatg tagcggcctt
     1441 cttcttcaga ccattcaaac atcggccagt caaccaccca aaggaagttg aacttatcat
     1501 tatcaatcaa gccaagctct ttagcaatac gtccacgaag ggcacccagt gttgcattaa
     1561 ccacttcaag cgtatccgcc acaaagagaa ccaagtcctt atcttcaaga gcaagcgctg
     1621 ttgtcaattc ttcttggata ccagtcaaga acttggcaac tggtccgttt aattctccat
     1681 caaccacctt gacccaagca agacctttgg caccatactg tttggctact tccgtcatct
     1741 tgtcgatgtc tttacgtgaa tagttgtccg cagctccttt gaccacaatc gcttttacag
     1801 caggtgcttc tgaaaagact ttaaagtcta cacctttgac cacttctgtc aagtcctgaa
     1861 gcaacatgtc aaaacgagta tctggcttgt cagaaccgta aagagccata gcatcatcgt
     1921 atttcatacg agggaacggt agcgttactt cgatgccttt tgtttccttc atcacgcgcg
     1981 cgatcaagcc ttctgtaata tcttggattt ctttctcagt aaggaaggac gtttccaagt
     2041 cgacctgagt aaattcaggc tggcggtctc cacgcaagtc ctcgtcacgg aaacatttaa
     2101 cgatttggta gtaacggtca aaaccagcat tcatcaagag ctgtttcgtg atttgtggac
     2161 tttgaggaag agcgtaaaaa tgccccttat taacacgaga cggcactaaa taatcacgcg
     2221 ccccttcagg cgttgactta gaaaggaatg gtgtctccac gtcgataaac tccaactcat
     2281 ccaaatagtt gcggatagag tgggtcacct tggcacgaag tttaagattt tccaacattt
     2341 ctggacgacg aaggtcaagg taacggtaac gcaaacgtgt atcgtcattt gcctcaatgc
     2401 catccttaat ctcaaatggt gttgtcttag ctgtgttaag cacaataaga gctgtcacgt
     2461 ttaactcaac cgcaccagtt ggcaacttat cattggcttg ctcacgcgca gcgacctgac
     2521 cagtcacctc aataacaaat tcgctacgaa ggctttcagc tgttgccata acctctgcag
     2581 atactttttc agggttgata accaactgca tgattccttc acggtcacga agatcgataa
     2641 agatcaaacc accaaggtta cgacgacggc caacccatcc tttcaaggtt atttcttgtc
     2701 cgatgtgttc ctcacgaaca cgaccagcat acatactacg tttcattatt tctctcctct
     2761 tttattctgt tactatttta ccataaaagc gcaggctctt catgaaaatc atcagaaaag
     2821 tttgccagtc tttaaaagtc aggtgaaagc cctaaaaatt agcgctaatg ctcttcgaaa
     2881 atctcttcaa accacgtcag cgtcgcctt
//
LOCUS       DAVBNZ010000099         2853 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000099 DAVBNZ010000000
VERSION     DAVBNZ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.100"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            108..824
                     /locus_tag="VQ860_002082"
     CDS             108..824
                     /locus_tag="VQ860_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET3120442.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            1133..1558
                     /gene="rplK"
                     /locus_tag="VQ860_002083"
     CDS             1133..1558
                     /gene="rplK"
                     /locus_tag="VQ860_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET3120443.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            1766..2455
                     /gene="rplA"
                     /locus_tag="VQ860_002084"
     CDS             1766..2455
                     /gene="rplA"
                     /locus_tag="VQ860_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET3120444.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
BASE COUNT          955 a          535 c          642 g          721 t
ORIGIN      
        1 attatcaatc atgaactagg attctagttt tgcaggaagt ctattaaaag attagtcaaa
       61 cgtttatcat cagaagtaga taaactatta gaaataaagg agtagaaatg aagaaaagat
      121 accttgtcgt gacagccttg ctagccttga gtctagcagc ttgttcacaa gaaaaagcaa
      181 aaaatgaaga tggcacagct aagacagaac agacagccaa agctgatggg acagtcggca
      241 gtaagtctca aggggctgcc cagaaaaaag cagaagtggt caataaaggt gattactaca
      301 gcatccaagg aaaatacgac gaaatcatcg tagccaataa acattatcct ttgtcgaaag
      361 actataatcc gggggaaaat ccaacagcca aggctgagtt ggtcaaactc atcaaagcga
      421 tgcaagaggc aggtttccct attagtgatc attacagtgg ttttagaagt tatgaaactc
      481 agaccaagct ctatcaagat tatgtcaacc aagatggaaa ggcagcagct gaccgttact
      541 ctgcccgtcc tggctatagc gaacaccaga caggcttggc ctttgatgtg attgggactg
      601 atggtgattt ggtgacagaa gaaaaagcag cccaatggct cttggatcat gcagctgatt
      661 atggctttgt tgtccgttat ctcaaaggca aggaaaagga aacaggctat atggctgagg
      721 aatggcacct gcgttatgta ggaaaagaag ctaaagaaat tgctgcaagt ggtctcagtt
      781 tggaagaata ctatggcttt gaaggcggag actacgtcga ttaatactct tcgaaaatct
      841 cttcaaacca cgtcagcgtc gccttaccta ctgactgcgt cggttctatt cacaacctca
      901 aaacagtgtt ttgagctgac ttcgtcagtt ttatctgcaa tctcaaagct gtactttgag
      961 cagcctacag ctagcttcct agtttgctct ttgattttca ttgagtataa aaaataaact
     1021 tttctcttgc aattccagat aaatagtgta taatggatgg gtatgtgaaa aacatacttg
     1081 tgggaggtaa aaatctctaa ttaccgccaa aaccacaaag gaggatttaa aaatggctaa
     1141 aaaagtcgaa aaacttgtaa aattgcaaat ccctgctggt aaagctacac cagctccacc
     1201 ggttggacct gctcttggtc aagctggtat caacatcatg ggattcacaa aagagttcaa
     1261 cgctcgtaca gctgaccaag ctggtatgat cattccagtt gttatctcag tttacgaaga
     1321 taaatcattt actttcgtta cgaaaacacc accagctgct gttcttttga aaaaagctgc
     1381 aggtgttgaa aaaggatcag gtacacctaa taaaactaaa gttgctacag ttactcgtgc
     1441 acaagtacaa gaaattgcag aaactaagat gccagatttg aacgcagcaa acgtagagtc
     1501 tgcaatgcgt atgatcgaag gtactgctcg ttctatggga ttcactgttg ttgactaatc
     1561 aataacacag tagaaaatct cacagcagtc tattagttgc ttttcatact aggcaagtga
     1621 ctgaggcttg tacttgggta cagcaaggga gcttaaggcc gtaggaagag aaaaatagta
     1681 gactgaaaac ccgcaagact tcatcatttc gagaagtgac gtgggagatg aaaatcgatt
     1741 gaaccactta caaggagaat agaaaatggc taaaaaaagc aaacaacttc gtgctgctct
     1801 tgagaaaatc gacagcacaa aagcatacag cgtagaagaa gctgtagcac ttgcaaaaga
     1861 aactaacttt gcaaaatttg acgcaactgt agaagttgct tacaacttga acatcgacgt
     1921 taaaaaagct gaccaacaaa tccgtggagc aatggtattg ccaaacggta ctggtaaaac
     1981 ttcacgtgtt cttgttttcg cacgtggtgc aaaagctgaa gaagcaaaag ctgctggtgc
     2041 agactttgtt ggtgaagatg accttgttgc taaaatcaac gacggttggt tggatttcga
     2101 cgtagttatc gctacacctg atatgatggc tcttgttgga cgtcttggac gtgtccttgg
     2161 accacgtaac ttgatgccaa accctaaaac tggtactgta acaatggatg ttgctaaagc
     2221 agttgaagag tctaaaggtg gtaaaatcac ttaccgtgct gaccgtgcag gtaacgttca
     2281 agcaatcatc ggtaaagtat catttgaagc tgaaaaattg gttgaaaact ttaaagcttt
     2341 caacgaaaca atccaaaaag caaaaccagc tacagctaaa ggaacttacg taacaaactt
     2401 gactatcaca actactcaag gtgttggtat caaagttgac gtaaactcac tttaatcagt
     2461 agttaaagta atgtaaaaaa gttgaagacg ctatgtctca actttttttg atatacgacg
     2521 ggcatgtcgt atatctgagg tgtaaatcct cggtgggcac ctactactgg tgaacccaat
     2581 agcgattccc aagtctgact atcgtgaggt agcggattaa aacggtctgg ggatagaccg
     2641 ttttaagtct gacgctggaa ataagaatcg tcagaggaag ggatagcgaa atcgtggctc
     2701 tacgaacagg aacgtgataa taaggcctat atagcggata aggtatctgg ctggggcgac
     2761 cactatcaat tatagtaaaa tgaaataaga gtaggacgaa tcgatcaggg cagccaaatc
     2821 gatttctaac aatgttttag aagaagagat gta
//
LOCUS       DAVBNZ010000100         2658 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000100 DAVBNZ010000000
VERSION     DAVBNZ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.101"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            448..2553
                     /locus_tag="VQ860_002085"
     CDS             448..2553
                     /locus_tag="VQ860_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3120445.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTSEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
BASE COUNT          850 a          480 c          614 g          714 t
ORIGIN      
        1 tcctgatcga tttgtcctgt tcttatttca ttttaatata tagttttgag atggttgata
       61 gaactgacga agtcagctca aaacatggtt ttgaggttgt agataaggag aagctgatgt
      121 ggtttgaaga ggttttcgaa gagtgtaaaa aaatattggt cagttaaagc caaaactctt
      181 gaccttttct gaccaatgta gtatattatg aacgtaaggt aaatgaaagc cttactagaa
      241 cacttattta aagtaaaata gaaagaggtg ggtctatgtt tcatctagaa atcttcagaa
      301 gtaaagatgg tctactcctg cttgaaaaag aaaaaccaga aatagtacgt agggtagcgg
      361 tttaactagt ctaaattttt taaaacaatg gtcaaagata gtcaatatca gtaatcataa
      421 ctaagtaaac aaaaagaggt aaagaatatg aataacaact ttaataattt taataacatg
      481 gatgatttat ttaaccaatt gatgggtggt atgcgaggat atagttctga aaatcgccgt
      541 tacttaatta atggacgcga agtcacatct gaggaatttg ctcactatcg tgcgactggt
      601 caattaccag gaaatgcaga aactgatgtg caaatgccac aacaggcatc aggtatgaaa
      661 caagacggtg tccttgcaaa actaggtcga aacttgacag cagaagcgcg tgagggtaag
      721 ttggatcctg ttatcggacg aaacaaggaa attcaagaaa catctgaaat cctctcacgc
      781 cgcaccaaga acaatcctgt tttggtcgga gatgcaggtg ttggtaagac agcagttgtc
      841 gaaggtctag cgcaagccat tgtgaacgga gatgttcctg ctgctatcaa gaacaaggaa
      901 attatttcta ttgatatctc aggtcttgag gctggtactc aataccgtgg tagctttgaa
      961 gaaaatgtcc aaaacttagt caatgaagtg aaagaagcag ggaatattat cctcttcttt
     1021 gatgaaattc accaaattct tggtgctggt agcactggtg gagacagtgg ttctaaagga
     1081 cttgcggata ttctcaagcc agctctctct cgtggagaat tgacagtgat tggggcaaca
     1141 actcaagacg aataccgtaa caccatcttg aagaatgctg ctcttgctcg tcgtttcaac
     1201 gaagtgaagg tcaatgctcc ttcagcagag aatactttta aaattcttca aggcattcgt
     1261 gacctctatc aacaacatca caatgtcatc ttgccagacg aagtcttgaa agcagcggtg
     1321 gattattctg ttcaatacat tcctcaacgt agcttgccag ataaggctat tgaccttgtc
     1381 gatgtaacag ctgctcactt ggcggctcaa catccagtaa cagatgtgca tgctgttgaa
     1441 cgagaaatcg aaacggaaaa agacaagcaa gaaaaagcag ttgaagcaga agattttgaa
     1501 gcagctctaa actataaaac gcgcattgca gaattggaaa ggaaaatcga aaaccacaca
     1561 gaagatatga aagtgactgc aagtgtcaac gatgtggctg aatctgtgga acgaatgaca
     1621 ggtatcccag tatcgcaaat gggagcttca gatatcgaac gtttgaaaga tatggctcat
     1681 cgcttgcaag acaaggtgat tggtcaagat aaggccgtag aagctgtagc tcgtgctatc
     1741 cgtcgtaacc gtgctggttt tgatgaagga aatcgcccaa tcggcagctt cctctttgta
     1801 gggtctactg gggttggtaa gacggagctt gctaagcaat tggcactcga tatgtttgga
     1861 acccaggatg cgattatccg tttggatatg tctgaataca gtgaccgcac agctgtttct
     1921 aagctaattg gtacaacagc aggctatgtg ggttatgatg acaatagcaa taccttaaca
     1981 gaacgtgttc gtcgcaatcc atactctatc attctcttgg atgaaattga aaaggctgac
     2041 cctcaagtta ttacccttct cctccaagtt ctagatgatg gtcgtttgac agatggtcaa
     2101 ggaaatacag taaacttcaa gaacactgtc attattgcga cctcaaatgc tggatttggc
     2161 tatgaagcca acttgacaga agatgcggat aaaccagaat tgatggaccg tttgaaaccc
     2221 ttcttccgtc cagaattcct caaccgcttt aatgcagtca tcgagttctc acacttgact
     2281 aaggaagacc tttctaagat tgtagatttg atgttggctg aagttaacca aaccttggct
     2341 aagaaagaca ttgacttggt agtcagtcaa gcggctaaag attatatcac agaagaaggt
     2401 tacgacgaag tcatgggggt tcgtcctctc cgtcgagtgg ttgaacaaga aattcgtgat
     2461 aaggtgacag acttccactt ggatcattta gatgctaaac atctggaagc agatatggaa
     2521 gatggcgttt tggttattcg tgagaaagcc taagacagaa ttttgaggat aaaaaagaag
     2581 gagccagctg aaaaaaactg gttcctttct aggtacgacg ggcatgtcgt gtagtaggtt
     2641 gaaactagaa tagtacac
//
LOCUS       DAVBNZ010000101         2535 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000101 DAVBNZ010000000
VERSION     DAVBNZ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.102"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..559
                     /locus_tag="VQ860_002086"
     CDS             <1..559
                     /locus_tag="VQ860_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3120446.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VQ860_002087"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VQ860_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HET3120447.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1424..2029
                     /locus_tag="VQ860_002088"
     CDS             1424..2029
                     /locus_tag="VQ860_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3120448.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(1977..>2535)
                     /locus_tag="VQ860_002089"
     CDS             complement(1977..>2535)
                     /locus_tag="VQ860_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3120449.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT          864 a          363 c          439 g          869 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagggat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgc
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg tcgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg gctcttatta tgggaatata cctatgaatt gggttgttat
     1501 aaaaataaaa gatatttttt caatgaatac aggtctttct tacaagaagg gcgatttaag
     1561 cattaataat aaaggtgtta gaattatacg tggtggtaat attaagcctt tagaattttc
     1621 tctgttggat aatgattact acattgatac acaattcatc tcctctgaac aagtttattt
     1681 aaaacataat cagctaataa cacctgtatc aacctcttta gaacatattg gaaagtttgc
     1741 aagaatcgat aaagactatg atggtgttgt ggctggtgga tttattttcc aattaacacc
     1801 attcgaaagt tcagagatta tttcaaaatt tctattattt aacttgtctt ctccgttatt
     1861 ttataaacaa ttgaaagcaa taactaaact atcaggtcaa gctttatata atattcctaa
     1921 aactacactg agcgagctat taattccgtt agctcctttt gaggaacagg aacttattac
     1981 tcaaaaagtt gagaaacttt ttgaaaaagt aaatcaactt tggaaatgat tcttttcatc
     2041 tcttcatgat tagaaatagg gattaataat tcggagatac tggtactatt taatgttttc
     2101 cctttgatag catcttttga atcacctaaa gtagagataa gtggcaaaaa tatcattaag
     2161 taatctctga taatattttc tttattagca taggggaata tcgatataat ggcttcatta
     2221 tgagtggcag gaatatccaa tatggcaact tttccaatag ataatttaaa actcattaat
     2281 aaagttcctt taggtgaaat gtctattttc tttgatttta atgctaattt agaaatagat
     2341 tctctcgtat tagttacata accagatata ggcatatctg atatagatac ccaaggtatt
     2401 tcagttcccc aaaaagtagc ttcactgcgt ggaggagttt ttcctattct gaagttaact
     2461 aggctagcaa atttaatata tctccatgct tctgggattt catatatagg ataagaggtt
     2521 gtttcgtctt tgttc
//
LOCUS       DAVBNZ010000102         2487 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000102 DAVBNZ010000000
VERSION     DAVBNZ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2487
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.103"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(173..838)
                     /locus_tag="VQ860_002090"
     CDS             complement(173..838)
                     /locus_tag="VQ860_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET3120450.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(852..2231)
                     /locus_tag="VQ860_002091"
     CDS             complement(852..2231)
                     /locus_tag="VQ860_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3120451.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRFIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
BASE COUNT          815 a          566 c          465 g          641 t
ORIGIN      
        1 cccgcagcta gtttcctagt ttgatctttg attttcattg agtattactc tctcttgtca
       61 cttccttcta ttttaccata aagtccagcc tttgaagaac ttttactaga agacaagggg
      121 cttctgtctc tatttgccat cttgggcatc aaaaaagagg ggtcatccct ctttacgaat
      181 tcaatgctac tagggtatcc aaatactggt tgttgatgac tgccaaaata taggtatctg
      241 ctttcaagag gtcatctggt ccaaattcaa catccaatgg ggaattttcc tgctctcgga
      301 aacccaaaat attcagattg tatttgccac ggaggtctaa tttactcaga ctttgacctg
      361 cccaagactg aggaattttc atctccacga tagacacatt tttatccaac tgaaagacat
      421 caacactatt atggaaaaga atggtctgtg ctagagactg ccccatttca tactctggcg
      481 agataaccga gtcagctcca atcttttcta gcactttctt agcggtctga cttttgacct
      541 tagcaataac agtcggtacc cccaaactct tacagtgcat aaccgcaagc acactcgact
      601 ccagattttc acctgtcgcg actacaacgg tatcgcaggt atcaatccct gctgatctca
      661 ataattcttc atctgtgatg tcaccaatca ctccacgcgc caaaactggc tcaaactgat
      721 tgatgcgctc tgcgtggtca tcaatagcga taatattcat atcctgcttg gctagggcag
      781 ctaggacact gctcccaaaa attcccaagc ccaaaattcc aatcgtacga tctgacatgc
      841 tctttccttt cttaaccaat actaatatct gctttcatat agtgaatcat atctttcttt
      901 tctggatggt aatctgccaa gctaacaaac aaggtcaagg gaccaattcg tcccataaac
      961 ataagtggca tgataacact gagagccaat ttcccaaggt caggagtcag atttgccgtt
     1021 acaccaactg tactaagagc tgaaatggtt tcaaatatga ggtggataaa gggaggattg
     1081 cctttggctg ttatccctag cagaatcaat cctatcaaga agctcatcaa aaagataata
     1141 aagacactaa aggatttttg aaccgttcgc ggcgcaatcg ttcgtctcgc aacattggca
     1201 tgaggcaagc ctagaagctc acttcgtgca aagaccaaga ggacaaaaaa tgtcgtaatc
     1261 ttgagtcccc cagctgttcc tccaggtgcc ccacctagaa acatctgtaa gatataaatc
     1321 aaaagagtca caggatgagc ctgagtataa tctatcgtag aaaagccagc tgttcgcatc
     1381 gtcactgttt gaaaaaagct aactaaaacc ttatcggcaa cagggagatt gccaatcgtt
     1441 ccagcattgt tccactcaag aaagagagta gttgccgttc caaataacaa caaacctata
     1501 gtcaacaata gtacaagctt cgtatgaaag tgcagacgtc cttttttctt tcttcctaca
     1561 tgaccagcca aatcaaacca gaccataaaa ccaaggccgc ctgtaataat caagcctgca
     1621 ataaccagat tgaccagtaa atcggtctga aaagcaaata aactggtgct ccctaaatta
     1681 tcaaaaccgg cattacagaa ggctgagatc gctagaaaaa tggaactaaa aagaccacgt
     1741 ccccagccaa gttgaggaat aaagcgaaaa ctaagcaaaa tagctcccaa gctctcaacc
     1801 aaaaaggtcg tgagaaaaat agaatagaca aactttctca aagatcgagt ttctccataa
     1861 ctaaaactat cctgaatagt tgcacggcta cgaagactaa gcttttgctt gctctggata
     1921 tagaaaaccc caataaaggt catgagccct agaccaccga tctgaatcaa gagcaaacag
     1981 attatttggc cccagatatt ataggtgtga gctactggaa gggttgagag acctgtcaca
     2041 cagactgcag agacagcagt gaaaagatga tcaaaataag tcgctcgtga gctttcaact
     2101 tggacaaagg gcaagctcaa aagaagagag cctagtaaaa tgaccaaggc aaaactcaaa
     2161 aaaatacgac gggctggcga taaacgagat aagcctagct ctattttttc cttagataat
     2221 ttgaataaca tgtttccatt gtaccataaa aagttcgaaa tgacttagat aggataaggc
     2281 aaaatctact aacaccaagc ctaaaaaatg ccaccttttt attgatagct taggcaagaa
     2341 caatacttga tagatgtgac tataggtcaa aaaagcaaga caggagcttt taacgccagc
     2401 tactctatat gcttttcagg agaaaatttc tctttttgat tataggcaat gagaaccaag
     2461 gcatcgctta gaaagctagt cacaggt
//
LOCUS       DAVBNZ010000103         2364 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000103 DAVBNZ010000000
VERSION     DAVBNZ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.104"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..1523
                     /gene="phtA"
                     /locus_tag="VQ860_002092"
     CDS             <1..1523
                     /gene="phtA"
                     /locus_tag="VQ860_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3120452.1"
                     /translation="FDPAQITSRTARGVAVPHGDHYHFIPYSHMSELEERIARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVGEGYVFEEK
                     GISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDKAYNLLTEA
                     HKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPERLGKPNSQI
                     EYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGKDSLSDKEK
                     VAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPYMVEHTVEV
                     KNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDERPHSNDGW
                     GNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLKEAEVLLAK
                     VTDSSLKANATETLAGLRNNLILQIMDNNSIMAEAEKLLALLKGSNPSSVSKEKIN"
     gene            1681..>2364
                     /locus_tag="VQ860_002093"
     CDS             1681..>2364
                     /locus_tag="VQ860_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3120453.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT          831 a          430 c          476 g          627 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa cagctagagg tgttgcagtg ccacacggag
       61 atcattacca cttcatccct tactctcaca tgtctgaatt ggaagaacga atcgctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaaggcca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccag gcccgcaacc tgcaccaaat cttaaaatag
      241 actcaaattc ttctttggtt agtcagctgg tacgaaaagt tggggaagga tatgtattcg
      301 aagaaaaggg catctctcgt tatgtctttg cgaaagattt accatctgaa actgttaaaa
      361 atcttgaaag taagttatca aaacaagaga gtgtttcaca cactttaact gctaaaaaag
      421 aaaatgttgc tcctcgtgac caagaatttt atgataaagc atataatctg ttaactgagg
      481 ctcataaagc cttgtttgaa aataagggtc gtaattctga tttccaagcc ttagacaaat
      541 tattagaacg cttgaatgat gaatcgacta ataaagaaaa attggtagat gatttattgg
      601 cattcctagc accaattacc catccagagc gacttggcaa gccaaattct caaattgagt
      661 atactgaaga cgaagttcgt attgctcaat tagctgataa gtatacaacg tcagatggtt
      721 acatttttga tgaacatgat ataatcagtg atgaaggaga tgcatatgta acgcctcata
      781 tgggccatag tcactggatt ggaaaagata gcctttctga taaggaaaaa gttgcagctc
      841 aagcctatac taaagaaaaa ggtatcctac ctccatctcc agacgcagat gttaaagcaa
      901 atccaactgg agatagtgca gcagctattt acaatcgtgt gaaaggggaa aaacgaattc
      961 cactcgttcg acttccatat atggttgagc atacagttga ggttaaaaac ggtaatttga
     1021 ttattcctca taaggatcat taccataata ttaaatttgc ttggtttgat gatcacacat
     1081 acaaagctcc aaatggctat accttggaag atttgtttgc gacgattaag tactacgtag
     1141 aacaccctga cgaacgtcca cattctaatg atggatgggg caatgccagt gagcatgtgt
     1201 taggcaagaa agaccacagt gaagatccaa ataagaactt caaagcggat gaagagccag
     1261 tagaggaaac acctgctgag ccagaagtcc ctcaagtaga gactgaaaaa gtagaagccc
     1321 aactcaaaga agcagaagtt ttgcttgcga aagtaacgga ttctagtctg aaagccaatg
     1381 caacagaaac tctagctggt ttacgaaata atttgattct tcaaattatg gataacaata
     1441 gtatcatggc agaagcagaa aaattacttg cgttgttaaa aggaagtaat ccttcatctg
     1501 taagtaagga aaaaataaac taatgaaaaa tgaaagtctc gataaagagg ctttcatttt
     1561 tattatgtat atatgtaaaa ttcttgacaa gcaatattaa aaagagtaaa ctattaacta
     1621 gttaattaac cggtttatta ctttatagtg aatcaaatat acttaagaaa agaggaaaga
     1681 atgaaaatca ataaaaaata tctagctggg tcagtagcta cacttgtttt aagtgtctgt
     1741 gcttatgaac taggtttgca tcaagctcaa actgtaaaag aaaataatcg tgtttcctat
     1801 atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga ggttagcaag
     1861 cgtgaaggaa tcaatgccga acaaatcgtc atcaaaataa cagaccaagg ctatgtcact
     1921 tcacatgggg accactatca ttattacaat ggtaaggttc cttatgacgc tatcatcagt
     1981 gaagaattgc tgatgaagga tccaaactac cagctaaagg acgaggatat tatcagtgaa
     2041 atcaagggtg gttatgtgat taaggtagat ggaaaatact atgtttacct taaggatgca
     2101 gctcatgcgg ataatgtccg tacaaaagaa gaaatcaatc gacaaaaaca agagcatagt
     2161 caacatcgtg aaggtgggac tccaagaaac gatggtgctg ttgccttggc acgttcacag
     2221 ggacgctaca ccacagatga tggttatatc tttaatgctt ctgatatcat tgaagatact
     2281 ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa gaatgagtta
     2341 tcagctagcg agttagctgc tgca
//
LOCUS       DAVBNZ010000104         1912 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000104 DAVBNZ010000000
VERSION     DAVBNZ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.105"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(400..780)
                     /locus_tag="VQ860_002094"
                     /pseudo
     CDS             complement(400..780)
                     /locus_tag="VQ860_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            complement(1202..>1912)
                     /gene="phtB"
                     /locus_tag="VQ860_002095"
     CDS             complement(1202..>1912)
                     /gene="phtB"
                     /locus_tag="VQ860_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET3120454.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPNEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESP
                     EESPEESEEPQVETEKVKEKLREAEDLLGKIQNPIIKSNAKETLTGLKNNLLFGTQDN
                     NTIMAEAEKLLALLKESK"
BASE COUNT          557 a          388 c          293 g          674 t
ORIGIN      
        1 caattaacta atttaatcac ttaaaaaaat tcgaacactt tctatacaac tgacagctca
       61 aatctttcag aatagaacaa tactaactat cgagcacccc gtattcataa atatatgtgt
      121 aattctagac ctagaattcc tataaactaa atgctttcat actcttccaa gtaattgatt
      181 gccttaaatt ttaatttttg aaggtttcta aagctagaat agccccatca caatcagttt
      241 tgattgattc acaatttaga aacactatag tttcactcct gttaaaataa aaaggaactg
      301 cataaagcaa tccctttctg attttgaaat catttactta acattttata gttgagataa
      361 tcaatagctt acctataaaa agagttatag taaaattcct tatttattga tttcaagctc
      421 cgctaactgt gtttgaataa ctgacagttc tgcaccagcc tgaagaagag cagctgcatt
      481 ataggcacct tctacaattg gaaccctgtt gatgatgata cttttatcac tgaaatcagt
      541 caccattttt aagttcattt tagcaaaacc taggtcaaaa aaggcaagta aagtatctgc
      601 tgtattttcg gaaacaaccc tatctactta atcaaaactc gttccaattc ctccgccctc
      661 ggttcctcct acataagtaa tcggaacatc tttagctact ttactaatca gttcaacaac
      721 accttctaca atgtatttgg aatgtgaaac gataacaaga ccaataccaa tactttccat
      781 caaaccaccc cagtttctaa aatagcagta aagagtaatc ctgatgagaa tgatccagga
      841 tcaatatgtc caagaaacca catgctccta agacaagagc taacagactg gccatcaata
      901 atagtattgt tctttttttc atcattactc cttaactagt gtttaactga tcaattagcc
      961 agtaaatagt ttatctttat ttacactatc tgttaagata tagtaaaatg aaataagaac
     1021 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtatacta ttctagtttc
     1081 aatctactat attttgcaca ttttcatgaa aaaaatgaga actagaactc acattctgct
     1141 ctcatttttc gttttcccgt tctcctatcc tgtttttagg agttagaaaa tgctgctacc
     1201 tttacttact ctcctttaat aaagccaata gtttttcagc ttctgccata atagtattgt
     1261 tgtcctgggt gccaaatagt aaattatttt ttaatcctgt gagagtctct ttggcattgg
     1321 acttgataat tggattctgg atttttccaa gtaaatcttc agcctctctc agtttttctt
     1381 taaccttttc agtctcgacc tgaggttctt ctgattcctc tggtgattct tctggtgatt
     1441 cttcttctgg ttcctctgtt ggttttggag actctggttt ctcgctttgc ggtttctctt
     1501 ctcgaggggt ttcttcctca ggtttttctg tctgaggttt ctcctcgttt ggtttttccg
     1561 tttgattggt atcagcttga ccatttttgt ttctttgaac atggtcgcta gcgttaccaa
     1621 aaccattatc tgaatgcgga cgttcgtttg gatgttcgac atagtacttg acagtcgcca
     1681 aaagatcctc aagactatac cccttaggtg cctcataaag gccttcgtca aaccactcaa
     1741 atttgatgtt atggtaatgg tcataatgag gtatgattaa actaccgttt ttgacttcta
     1801 cagtatattg aagattgtaa ggcatacgat caagtggcac cttcttagct gctttcacgc
     1861 ggttgtagat agcttctgct ccttttgcct cagtatttcc tgaatcctga tg
//
LOCUS       DAVBNZ010000105         1889 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000105 DAVBNZ010000000
VERSION     DAVBNZ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1889
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.106"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(<1..917)
                     /locus_tag="VQ860_002096"
     CDS             complement(<1..917)
                     /locus_tag="VQ860_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3120455.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREVASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLPYPRKGKALKKQASTNFKPAGQ
                     SIAQRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYASWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCL"
     gene            complement(1362..1760)
                     /locus_tag="VQ860_002097"
     CDS             complement(1362..1760)
                     /locus_tag="VQ860_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3120456.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          514 a          385 c          326 g          664 t
ORIGIN      
        1 tccaagcatt ttttaggata gttgttaatc cacttttcga tgaatgcgac ttctttggga
       61 gtcattttct tggttccctt aggtaaccat ctacgaatga acctgttgtg attctcatta
      121 gttccccttt cccaagaggc ataggggtgc gcataataaa tgtgctcctc agaaaataca
      181 tcagacaagc gattgaattc cgttccatta tctgccgtga tggaaagaat cttgtgttgt
      241 tttaagatga gttttagagc ctgattgacc acctcagcac ttttatttgg aatcaatcgg
      301 atgatctgat gtctactctt tcgatccgtc aagacaagca agcagtagtt tttcgctctc
      361 gtaagtagaa ccgtatcaat ctcataatgc ccattctcca agcgaagatt gatagcttca
      421 ggccgctgtg cgatggattg accagcaggt ttaaagttgg tgctggcctg tttcttaagc
      481 gcttttcctt ttctagggta aggcaaatcc tgcttgctta accccaattt tccatgatga
      541 atccaatagt aaatggttga aattcccacg ttaacccctt tagccatcac catcatttca
      601 ggcgaaaatt tttggttatg atagtggaga atcttttcct ttagttcctt ggtcaagctt
      661 gatttcttga ccgagcgctt gcgattgttt tcataagact gttgagcgta gtcggcagaa
      721 taaacctctt tgaagcgccc ttttccaaga cattgtcgga ctgtcccacg cttgatttca
      781 gtgtggatag tttgaggagc ttttccaagt agagaggcaa cttctctatt tgattttcct
      841 tcttttttcc atctttcgat taagcgacgg ctatcgattg tcaaatgttt accttttgta
      901 gtataattgt cttgcatttc tgtgcctttc ttgtgtttgt ggttgaacaa caagtataac
      961 acagaggtgt tttcttatgc ctacaagagc tttcattatt tccattttct tttggatttc
     1021 actctattct gaaaaacttg tgtatattta ctgaagctag caagtcttac ctgtaaattt
     1081 aatgaaagca acacaaaatc cgagagggga atctcggatt aatagataga gagtttttag
     1141 tttaaataaa ttgtttaaaa tatcaacaac atcacttctt ttcttaacct gataagtctt
     1201 gattcctaat tttggggcta cgattatatt gtcctcaata tcgtctagaa agacacaatt
     1261 tctaggttat aactggtatt tatcgatagt tactcatata catcagtcca cctccatact
     1321 tatgtgcgag cctctctttg tattatacct ccatactcac cttacagatt cttttggtaa
     1381 taatatcttt gcctaatgta gagatagtct tgcaaagaaa aaacttcctt gtagccatgt
     1441 ttctgataaa agtccggtgc ctggaactgg taagtattga caaaggcaaa acaacaattt
     1501 cgattcttag cttcactttc tgcctgttgc aatagttttg aaccgattcc ttgccctcgc
     1561 agttcctctt ttacaaacaa atactcgatt tctagccaat ttccaaaagt ctctgctatc
     1621 aaacctgcca ggagattgcc cttttcatct tcgacataaa gattaagtgg ctcactttca
     1681 gcctcttctc tttttgaacg gttataaaca cgaatcagat tccctatttc ttgcgattta
     1741 tgtgattcct tattttccaa tctaatgaaa tgaaataaaa catgcgcaaa tcgattaagg
     1801 aatttaatct aatttctaac aatgtcttag aaatcaaagt gtactatttt aacttcaatg
     1861 cactatacat ctaatactca atgaaaatc
//
LOCUS       DAVBNZ010000106         1860 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000106 DAVBNZ010000000
VERSION     DAVBNZ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.107"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(3..968)
                     /locus_tag="VQ860_002098"
     CDS             complement(3..968)
                     /locus_tag="VQ860_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3120457.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1086..1499)
                     /locus_tag="VQ860_002099"
     CDS             complement(1086..1499)
                     /locus_tag="VQ860_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET3120458.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1496..1732)
                     /locus_tag="VQ860_002100"
     CDS             complement(1496..1732)
                     /locus_tag="VQ860_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET3120459.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          541 a          363 c          276 g          680 t
ORIGIN      
        1 ttttaagaga tgaatttttg gtgtgaatgc ttgacattat tttgattgac catggcatag
       61 gccagggttg tgtcaatctt gctatgacct agcagttttt ggacttgttc gataggcata
      121 cctttatcaa ttgccttagt cgctaaagtt cttctgaact tatgtgggtg aaccttttgt
      181 atgccgagtt tgtctcctaa ctttcttaag cgaatctcta caccagcaat tccaagtctc
      241 tgggcttttc caactagcgt tacaaaaaga gcagggtgac tatcttttct gtcgttaaga
      301 taatttctta aatgaatttt cgtccgagcg tcaaaatata ctggtctctc cttctttcct
      361 ttaccaaaga caacacactc tctgttttca aaatcaatat ctgaacgatt caactgtaca
      421 agctccccta cacgcatacc tgtcgatgct agtaggtcta ttattgccaa atctctcaaa
      481 ttttcacagt tatcacgcat aatttccaaa tgttcatcag tataagtttc cttcacattt
      541 tgctcagtct taattttctt tatccgtcga atgggatttt taatgatata ttcctcttgc
      601 tcaagccaag caaaaaaaga agacaatata cgcctaatat tgtctaaatt tgccttacta
      661 caatcctttt cagactggta atttgctaaa taactcctta aatcatctgt tgtgagttgt
      721 gtcacagact ctttaatagc attaaacaag ttttcaatcg tcctctggta ataacgaatt
      781 gtttttgagc tacagccctc tacctgcttg gcggtaataa atagttgcaa caggttatta
      841 ttcgaatact tctgctgctt ttttccgtct actagatgat gttctaaact ctctctcaac
      901 gctagtaatt gttcattatt taaaagaggt aacatttctt gcatgataat tgtaactttt
      961 gattccataa tttctcactt tcttattcat caataaaaag agacaatatc agtttctgca
     1021 ttacagaatt ctaatattgt ctgttcattt attttcttgt gctcattcaa atccagcata
     1081 ctaggttact ttttgacctt ttctctaaca gaatgttcag aaacccattt ggagtagctt
     1141 gtcatttttt catcagttaa agcttctact gcgatggtta cacacatttt tactgcttct
     1201 tctaccgtta cagaaaaacg atagccgttt aattgtaaaa atttgaccaa aacgaagaaa
     1261 gcagttcttt tattagcatt agcaaaaaca tgcttcttta tcaattggac aaatagtatc
     1321 gttgctttat caaaaattgt tggataaaga gacttcccaa agacaaattg ttctggtaag
     1381 ttcacaatca tatttaaggc agaagaacta actgtttgaa ttttctcatt tggagaatac
     1441 cgttgaattg ctaaagcatt tattttttca atttgctttt ctgtcagata gattgtcatt
     1501 tttccaccaa agctttgaaa acatcgtcgt attcgtcaaa tattttatct aaatttaagt
     1561 caaaggcatc atcagataca taagaaacct gctgccccaa ttcttcagga gtaaagataa
     1621 tctcaccact tggtaacaat ttcgcttcgt atttaacacc acttggaata ttaaattcac
     1681 ttggaatcgt aatggtgatt gaatttcctt gttttcttgt ttttactacc atctgatttc
     1741 ctcctttgaa gtattataac aaatcattac cgtaattaca atggcagaat atcagccaaa
     1801 atactcctgc atcagagatt tcttcaaagt ttcaagttct tccagagatt tttggattgc
//
LOCUS       DAVBNZ010000107         1646 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000107 DAVBNZ010000000
VERSION     DAVBNZ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.108"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(242..1006)
                     /locus_tag="VQ860_002101"
     CDS             complement(242..1006)
                     /locus_tag="VQ860_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET3120460.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLNQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1228..1524
                     /locus_tag="VQ860_002102"
     CDS             1228..1524
                     /locus_tag="VQ860_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3120461.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPDAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
BASE COUNT          522 a          404 c          316 g          404 t
ORIGIN      
        1 gaagctgacc tggtttgaag agattttcga agagtatcat ttcatctcac tctaaatctt
       61 accaacataa aacgcatagt atcaaagttt tcatcacctg atatgatacg tttttctgat
      121 tttaaagatt tttcccaacc tcaacatgcc taggacaaga ggaaggtaac ctcgtttaaa
      181 catatttttg aaaagtatga gctaggcatt ttatgataaa acaaatcctt tgccagtaca
      241 actaaaggtg gtgaacactt gctaaactca gttctagcgc cttattaaaa gcttccgagc
      301 cccagtcacg actgtcgtac tggttcaagt ccgctagaga atctgctgtg aacaacaatt
      361 caccccagag aaccccacgc aattgagcta ctgccgcaag agcagaacac tccatctcca
      421 caacagcaca gtcttcttcc ttgcgataag ccaccttttc agccgtttct cggtaaaaac
      481 catctgtgga ccaggtcatg acttcttcat aaggaatccc tctatcatcc aaaactcgct
      541 caatggcagc aatagcctct ggctgcattt ccatataacg agaaggtgcc acatagtggt
      601 aactggctcc ttcatctcgc agagcgcgaa cagggactag aaaggcattt tcctctatat
      661 cagctaggac accacaggtc ccagtagaga taatctgctc cacaccatag ccaatcaacc
      721 aatccataaa ctgggctgct ggagctgaac cgacaggagc ctgaaccaga caaatctcct
      781 cgtccttgta gttcacgaca taaactggat aggtcttggt ggcagaaaca aattcgccaa
      841 cacagttcgc ccctacttcc ctcgcatagc ggtcaatctc ctcacctaaa aaagcataga
      901 cacacttctt tggcaactgc aaatccaacc cctcgtgatt gggcatgata accgcctgag
      961 gattatcatc aaactctaaa ataggaatcg catgtttctg aatcatagcc cacctcctct
     1021 aattttgtac tattgtatca aaatctgaca aagtgtcaag gaggaagctg atgaactgag
     1081 gagaaaaaca agcctacatc gtcagctgcc acagtggttt gcgcagctat atcgcagagc
     1141 ctatcctcaa gcaagcagga tttaccgtcc aaaaccttga cggcgcttat tcactataca
     1201 aaatgactaa cccagaagga gtagaatatg gaaactagta tcagcatggc tgacttttat
     1261 ggaaaatatc aaaatgaaaa tctagaactt atcgatgtcc gtgaagcaca tgaattccaa
     1321 gcaggacatg caccagatgc caaaaatctt ccattaagta ccttagagca aggctacaaa
     1381 gaactcaaac ctgaccatga atactatgtt atttgtcaag gaggagtccg ctctgcatct
     1441 acctgccaat ttctcagctc ccaaggcctc accgttacca acgtagaagg tggtatgaat
     1501 gcttggcccg gtcaagtaga ataatcaaga ggagctgggc aaaaactcaa tttcaggaga
     1561 agatgaagta atactcaatg aaaattaaag tgcaaactag gaagttagcc gcaggctgct
     1621 caaaacactg ttttaaggtt gtggat
//
LOCUS       DAVBNZ010000108         1409 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000108 DAVBNZ010000000
VERSION     DAVBNZ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.109"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            283..1293
                     /gene="ccpA"
                     /locus_tag="VQ860_002103"
     CDS             283..1293
                     /gene="ccpA"
                     /locus_tag="VQ860_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET3120462.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
BASE COUNT          440 a          232 c          318 g          419 t
ORIGIN      
        1 tcctgttctt atttcatttt actataactt taggagggct tagtttcctc ctttttgttt
       61 agtctaaggt ggtagcaagg agctaaacct aggttttcta tgaaattttt tcaatcaatc
      121 ttcaaaaaac acttgaaagt gtttacaatt agtgatagaa tggaataagt agaaatatga
      181 aaacgaaatt ttcacatctt cacttttgta agtagatata gagcttcaat cagcacctct
      241 acttgtaaaa gaatatgtga gatagaaagg acaggaaaag gaatgaatgc agatgataca
      301 gtaaccattt atgatgtcgc tcgtgaagca ggtgtttcca tggcgacggt cagccgtgtg
      361 gtcaatggca ataaaaatgt aaaagagaat acccgtaaaa aagtgctaga ggtaattgat
      421 cgtttggatt atcgtccaaa tgcagttgcg cgtggtcttg caagtaaaaa gacaaccact
      481 gtcggtgtcg tgattccaaa tattaccaat ggttattttt cgagtttggc taaggggatt
      541 gatgatattg cagaaatgta caagtacaat attgtcctag ctaatagcga tgaagataac
      601 gagaaagaag tttctgttgt caataccctc ttttcaaagc aggtagatgg cattatctat
      661 atgggttatc acttgacaga taaaattcgc tcagaatttt cgcgctcacg tactccgatt
      721 gttctcgcag gaactgtcga tgttgagcac cagttgccaa gtgtcaatat tgactataag
      781 caagcaacaa ttgatgcagt gagttacctt gctaaagaaa atgagcgtat tgctttcgtt
      841 agcggtccgc tagtggatga catcaatggt aaggttcgtt tagttggcta caaggaaacc
      901 ttgaaaaaag caggaatcac ttatagtgag ggtttggtat ttgaatctaa atatagctat
      961 gatgatggtt acgccttagc agagcgtttg atttcatcaa atgcaactgc agcagttgtg
     1021 acaggtgatg agttggcagc aggagtcttg aacggtttgg ctgataaagg tgtttctgtg
     1081 ccagaagatt ttgaaattat tactagtgat gattcacaaa tctcacgctt tacccgtcca
     1141 aacttgacaa cgattgccca acctctttat gaccttggtg ctattagtat gcgtatgttg
     1201 accaagatta tgcataagga agagttggaa gaacgtgaag ttctcttacc tcatggtttg
     1261 acagaacgta gctcaacacg aaaacgtaaa tagaaaaaat cagggaatcg agaagatttc
     1321 ctgattttgt gctcttaaac aagagatgtt gacttaatga ataccataga gcggactagg
     1381 cggctggtta aaggctgcgc aacacactg
//
LOCUS       DAVBNZ010000109         1267 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000109 DAVBNZ010000000
VERSION     DAVBNZ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1267
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.110"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            250..590
                     /gene="tnpB"
                     /locus_tag="VQ860_002104"
                     /pseudo
     CDS             250..590
                     /gene="tnpB"
                     /locus_tag="VQ860_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(623..1267)
                     /locus_tag="VQ860_002105"
                     /pseudo
     CDS             complement(623..1267)
                     /locus_tag="VQ860_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          382 a          251 c          228 g          406 t
ORIGIN      
        1 aatttcataa taaaaacacc ccaaaagtta gattttttct gtctaacttt tggggggcag
       61 ttcattctac acccactatt atgcgttttt atcattttga aatctactgc taatcaatga
      121 agaagcaaag atcaaactag gcagctagtt acaagttacg taagcgcgtc ataacaaggt
      181 atctatccta attccccaac ttccagtata ctagataaaa aataattatc ggaggaaagg
      241 tattgtacta tgataattca actaagtgat ttaggtcaag ttcaccttgt ttgtagcaag
      301 atagatatga ggcagggaat agactcatta gcctatgtag ttaaaaccca ctttgaattg
      361 gatcctttct ccggtcaagt ctttctcttt tgtggtggac gtaaagaccg ctttaaagcc
      421 ctttactggg atggtcaagg attttggcta ctatataaac gctttgagaa cggcagactg
      481 acttggccca gtacagaaaa ggatgtcaaa gctctcacac ctgaacaagt agactggctt
      541 atgaagggct tttctatcac tccaaaaata aatccatcag aaagtcgtga tttctattga
      601 aatgaggact ttctttttat actcatctgc tttcaaaaag cattctagtc catctccgat
      661 taacgatggg ctttatcacc tccttctcca gtccttgtat gatatcttaa agttgattca
      721 tgacatcttc caaagtttga aaggctttat ttttaaatcc acgtttacga atctctttcc
      781 acacttgttc aatggggttc atctctggtg tgtatggagg aataaatgca aagccaatat
      841 tagtcggaat ctttaaggta cttgatttat gccatatagc attgtccata acgaataaaa
      901 gataatcatc tggataagct tgtgaaagct cttctaaaaa gacgttcatc cactcagtat
      961 tacatccacc agctattaag aaaaatgatt cgcctgtatg ggtccataac aatagcgaaa
     1021 ttctcgtata tagtgactat ggacatgtgg acctactcct attggagacc aacaagatcc
     1081 cagtttactg attctaccga agccagcctc atcttggtac atcaagcgaa ccttatgaaa
     1141 acgtctactg gttttaaagc gctttctttt cttcttgaat tgaaatttta tttttagacg
     1201 cgacaatggt ttgagcgtct gctttcttag gatgttctgg acgtggcata atatttcgcc
     1261 aaccatg
//
LOCUS       DAVBNZ010000110         1081 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000110 DAVBNZ010000000
VERSION     DAVBNZ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1081
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.111"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(790..1050)
                     /locus_tag="VQ860_002106"
     CDS             complement(790..1050)
                     /locus_tag="VQ860_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120463.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
BASE COUNT          361 a          203 c          172 g          345 t
ORIGIN      
        1 tatcaatcat gaactaggat tctagttttg caggaagtct attatatata tgcacagaca
       61 tatgaaatct ttttgataca gccttctttt tacatagaga gacagcagtt atgatatatt
      121 tatccattca caacatcttc tgtaccaata ctacaataat tggtacattt tgattacaca
      181 atcgtttcaa aaaatatgat ggaagactga gtattttata gtaattccct tcctatcaac
      241 tagatcaacc agttgagtgt tgaatgttga aacaccctag cctcagcaaa ggactatgat
      301 cagcatttcc tagccaatag gacgctccaa atcacctatt ctaagtccat cactagcttg
      361 gtcagtaaga tacagactgc aaggcaagac tgacgtggtt gatgagattt tggaagagta
      421 ttacaatcat agattcacca gtagacttga ccgcagattt aactatagta gattgaaact
      481 agaatagtac acttctgctt ctaaaacatt gttagaaatc gatttgactg tcctgatcaa
      541 tttgtcctgt tctcgtttca ttttactata ctaaaaaacc acctgaaaca aatcaagtga
      601 ctagaggata aaaacaaaga ctgggcaaaa agttttgaaa agcaaaaaac gcataatatc
      661 aggtcttgaa aaaccttgat actatacgtt tgattgtggg aagattgact tcattttctc
      721 ctgaaattga agttttttct agtttccagg tatagacgaa ttcaatatag ccatctcgct
      781 acaattattt taaccatcga aaaaattttt cagaatttca aaaatttcat tttgatctaa
      841 tgaaatgtca tcattttgaa gaatagttga cttcacaagc tctaattcta tcacaaagcg
      901 gtgcatgtct gcttttaccg cactacttga tgttatagcc gataactttt catctcctag
      961 caaggaagct gtcaaacggg taaggtcatt caaatgcttt ttaatggact tacttaaacc
     1021 ttgagcacct gtagcagagc gttccctcat atccagccaa gctttagcct taaaaataat
     1081 t
//
LOCUS       DAVBNZ010000111         1046 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000111 DAVBNZ010000000
VERSION     DAVBNZ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1046
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.112"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            84..491
                     /locus_tag="VQ860_002107"
     CDS             84..491
                     /locus_tag="VQ860_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3120464.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKID"
     gene            656..955
                     /locus_tag="VQ860_002108"
     CDS             656..955
                     /locus_tag="VQ860_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET3120465.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          371 a          211 c          182 g          282 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattgacta atactcttcg aaaataaaat ttaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcagctag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataata aaacgcatag
     1021 tagcaggtgc cgaaatgaac tgcacc
//
LOCUS       DAVBNZ010000112         1012 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000112 DAVBNZ010000000
VERSION     DAVBNZ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.113"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..117
                     /locus_tag="VQ860_002109"
     CDS             <1..117
                     /locus_tag="VQ860_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin transporter"
                     /protein_id="HET3120466.1"
                     /translation="KKDYIEFKRVGIFDGKAVEVTLREPYSRDLLQVVKSIK"
     gene            complement(414..701)
                     /locus_tag="VQ860_002110"
                     /pseudo
     CDS             complement(414..701)
                     /locus_tag="VQ860_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            700..963
                     /locus_tag="VQ860_002111"
                     /pseudo
     CDS             700..963
                     /locus_tag="VQ860_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          376 a          157 c          176 g          303 t
ORIGIN      
        1 aaaaaagact acattgaatt taaacgtgtt ggtatctttg atgggaaagc agtagaagtt
       61 actcttcgag aaccttattc gagagatcta ctgcaggttg tcaagtcaat aaagtaactg
      121 acaccacgag tataattatt agaaacgtgg aatcttatta aattttataa taaatatatt
      181 aaatgaaaaa ttattagata taaacttatg taataaaaca ttgaggaaat aataaaaatc
      241 tatgggtaat gttctgaaag tacttttagg ttaggagaga aatataatga tttttgaaaa
      301 ttgattcaaa aaatagcgaa ttgtagaaaa cgcttaacaa atggtgtata atagacttcc
      361 agcgaaacaa aatatgctac aataaaccta tgaattataa agtaacctta tactcatctg
      421 tcttcacaaa gcattctagt ccatctccga ttaacgatgg actttatcat ctccttctcc
      481 agtccttgta tgacatcttc caaagttcga aaggctttat tcttaaatcc acgtttacga
      541 atctctttcc acacttattc aatggggttc atttctggtg tgtatggagg aataaatgca
      601 aagccaatat tagtcggaat ctttaaggca cttgatttat gccatatagc attgtccata
      661 acgaataaaa gataatcatc tggataagct tgtgaaagct tggctgacag tggttatcaa
      721 gggctcatga agatatatct tcaagcacaa actccacgta aatccagcaa actcaagccg
      781 ctaacagctg aagataaagc ctataaccat gcgctatcta aggagagaag caaggttgag
      841 aatatttttg ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt
      901 aaacgcttcg gattacgaat gaatttgatt gctgatatta tcaatcatga actaggattc
      961 tagttttgca ggaagtctaa taaatgtata agaaaaagga ggaaaaagga tg
//
LOCUS       DAVBNZ010000113          863 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000113 DAVBNZ010000000
VERSION     DAVBNZ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.114"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            462..>863
                     /locus_tag="VQ860_002112"
     CDS             462..>863
                     /locus_tag="VQ860_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3120467.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKNLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGN"
BASE COUNT          299 a          134 c          157 g          273 t
ORIGIN      
        1 tatcctatct tctagaatgt cttccaaacg tggaaactct cgtaaacaaa gaggttttag
       61 aggcctattt accgtggact aaagttgtac aagaaaagtg caaataagaa atctccagat
      121 taggaactat atatgagttc actaatctgg agatttttca atagacttcg ttattgggcg
      181 gttaggatat gatcactgac ttcgtcagtc ttatctacaa cctcaaaaca gtgttttgag
      241 caacctgcgg ctagcttcct agtttactct ttgattttca ttgagtatta gaacagaaaa
      301 aatgcttgga gtatttgttt gtgtgtttat ttttatataa caaactataa acaaaacaaa
      361 aatataaaaa aagagacaaa aaagaacaga aagtaattga caacggtttc atatagtgtt
      421 atacttatgg cataaagtta atggaaagaa gggaaaaact tatggtatta gattatttct
      481 ttgacaaaaa ccttgtgttt tgcttagaag cggataatca agaacatctc tttgatcagg
      541 ttgcaacttt attggaagaa cgagaaattg taactccaac ttatcgtgaa gccttgatca
      601 cgcgtgaaaa gtcatttcca actggtttag atatggaatt tctaggaaag aacttgccaa
      661 atgtagcgat tcctcacaca gatattgttc ataatctagc tgagaaagtg gtggttgttc
      721 gattagaaaa accagtaact tttcacaata tgatagctcc tgataaggaa gtagaagtat
      781 ccctactctt ctttattatt aacaattcaa gttcaagtca aacaaatatt ctggctcagt
      841 tgatggactt tttcacagga aat
//
LOCUS       DAVBNZ010000114          847 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000114 DAVBNZ010000000
VERSION     DAVBNZ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.115"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ860_002113"
     tRNA            complement(74..147)
                     /locus_tag="VQ860_002113"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ860_002114"
     tRNA            complement(157..242)
                     /locus_tag="VQ860_002114"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ860_002115"
     tRNA            complement(250..321)
                     /locus_tag="VQ860_002115"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ860_002116"
     tRNA            complement(344..416)
                     /locus_tag="VQ860_002116"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ860_002117"
     tRNA            complement(435..516)
                     /locus_tag="VQ860_002117"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ860_002118"
     tRNA            complement(522..594)
                     /locus_tag="VQ860_002118"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ860_002119"
     tRNA            complement(619..691)
                     /locus_tag="VQ860_002119"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
     gene            complement(694..766)
                     /locus_tag="VQ860_002120"
     tRNA            complement(694..766)
                     /locus_tag="VQ860_002120"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Val,seq:tac)
BASE COUNT          212 a          251 c          186 g          198 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt atcttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ctttgggagt taacgggatc gaaccgctga
      721 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actccctaaa gctaagcgac
      781 ttccctatct cacagggggc aacccccaac tacttccggc gttctagggc ttaacttctg
      841 tgttcgg
//
LOCUS       DAVBNZ010000115          775 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000115 DAVBNZ010000000
VERSION     DAVBNZ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..775
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.116"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            3..305
                     /locus_tag="VQ860_002121"
     CDS             3..305
                     /locus_tag="VQ860_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3120468.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            313..775
                     /locus_tag="VQ860_002122"
                     /pseudo
     CDS             313..775
                     /locus_tag="VQ860_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          254 a          142 c          160 g          219 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagttatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattctgta
      241 tcccagcaat gagcgttcca gtatttgaca atattagact tcctgcgaaa caaaatatgg
      301 tatagtagtt ccatgaatta tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt
      361 cttgttggtg ttcaacgcac gacttttgaa gagatattag ctgtattaaa aacagcttat
      421 caacttaaac acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ctttcttatg
      481 gccactcttc aatatgtgcg agaatatcga acttatgaag aaattgcggc tgattttggt
      541 atccacgaaa gcaacttaat ccgtcggagc cgatgggttg aagtaactct tgttcaaagt
      601 ggtgttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
      661 gaagtacaaa tcaatcgccc taaaaaaaca attagcgaat tattctggta aaaagaaatt
      721 tcacgctatg aagtctcaag cgattgtcac aagtcaaggg agaattgttt ctttg
//
LOCUS       DAVBNZ010000116          759 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000116 DAVBNZ010000000
VERSION     DAVBNZ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.117"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..>759
                     /locus_tag="VQ860_002123"
     CDS             <1..>759
                     /locus_tag="VQ860_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3120469.1"
                     /translation="DGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQNKPEKSFRYIDTS
                     SIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLI
                     ASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLS
                     EQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDE
                     SVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQG"
BASE COUNT          297 a          110 c          121 g          231 t
ORIGIN      
        1 tgatggaagt actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt
       61 gaggataaaa tcaatttatt ggaattttgg gcaaaataag ccagagaaat cctttaggta
      121 tatagatacg tctagtattg atagaaaaaa gaacataatc aactacaaaa atctacaata
      181 tctttcacct gaacaagcgc cttcccgtgc cagaaaatta gtttcgcaga atagtgtctt
      241 attttcaaca gttagaccat atctaaaaaa tattgctgta gttagagaac ttaaagagta
      301 tttgatagct agtacagcat ttattgtttt ggatacttta cttaacgaaa catatttgaa
      361 atattattta ttatcagata attttatcaa tcgtgttaat aataaatcta ctggaacaag
      421 ttatcctgca atcaatgatt ataattttaa tctattatta attgctctcc ccccactatc
      481 cgaacaacaa cgaatagtag aagcaatcga atcagcttta gaaaaagtag atgaatatgc
      541 tgaaagttat aatagactag aacagctaga taaagaattt ccagataaac taaaaaaatc
      601 tattcttcaa tatgctatgc aaggaaaatt agttgaacaa gacccaaatg atgaatcagt
      661 cgaagtttta cttgaaaaaa tacgagcaga aaaacaaaaa ctctttgaag aaggcaagat
      721 taaaaagaaa gatttggaca tttctattgt ttcccaagg
//
LOCUS       DAVBNZ010000117          630 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000117 DAVBNZ010000000
VERSION     DAVBNZ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.118"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            47..408
                     /locus_tag="VQ860_002124"
                     /pseudo
     CDS             47..408
                     /locus_tag="VQ860_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
BASE COUNT          207 a           76 c          119 g          228 t
ORIGIN      
        1 ggctagtttc ctagtttgct ctttggtttt cattgagtat aacacattgt tagaagttgg
       61 tttaaatttc ctaatcagtt tgttcacatt taccttcgat atattatatc ccatagttaa
      121 ggttggtcat acagatgatt atagtcatgg agccgtaaaa cttagtgttt ctttagttga
      181 caaagatgcc atgaaaaaat atctgtaact gtaataggat attttgaaat aaatatagat
      241 gaaaatatca ccgatattct atacgtaaat ggtactgcta ttctttgtcc ttatttacgt
      301 tctattgttt caatagtttc ggcaattgat agcagtgaag caatgttgct acctaccatt
      361 aatgttttag agttactaga taaatctcaa ccttttgaag aagaataatt tattagctca
      421 ctaaattgag ggtaaggaaa agtaaaagca gtaagaaaaa tgtcttgcat tatacagcaa
      481 ccttttggga atgagtagat ggattgaata aaatttgatt aagagtggat gatttatctg
      541 tagattatta ttggacagtt agtcttgaag tagtctaaga attaggttat aatcagtaga
      601 agccttgcta ataatgagga ggttagttta
//
LOCUS       DAVBNZ010000118          601 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000118 DAVBNZ010000000
VERSION     DAVBNZ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..601
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.119"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..>601
                     /locus_tag="VQ860_002125"
     CDS             <1..>601
                     /locus_tag="VQ860_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3120470.1"
                     /translation="FDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYV
                     FEENGVPRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDL
                     LARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLV"
BASE COUNT          192 a          135 c          122 g          152 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa ccgccaatgg tgttgctgta ccgcacggag
       61 accattatca ctttattcct tattcacaac tgtcaccttt ggaagaaaaa ttggctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaagacca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccaa gtccgcaacc tgcaccaaat cctcaaccag
      241 ctccaagcaa tccaattgat gagaaattgg tcaaagaagc tgttcgaaaa gtaggcgatg
      301 gttatgtctt tgaggagaat ggagttcctc gttatatccc agccaaggat ctttcagcag
      361 aaacagcagc aggcattgat agcaaactgg ccaagcagga aagtttatct cataagctag
      421 gagctaagaa aactgacctc ccatctagtg atagagaatt ttacaataag gcttatgact
      481 tactagcaag aattcatcaa gatttacttg ataataaagg tcgacaagtt gattttgagg
      541 ctttggataa cctgttggaa cgactcaagg atgtctcaag tgataaagtc aagttagtgg
      601 a
//
LOCUS       DAVBNZ010000119          599 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000119 DAVBNZ010000000
VERSION     DAVBNZ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.120"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(21..500)
                     /locus_tag="VQ860_002126"
     CDS             complement(21..500)
                     /locus_tag="VQ860_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3120471.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          160 a          139 c           78 g          222 t
ORIGIN      
        1 attttttttt gcatgactta ctagtgggta cggatagtaa actccttaaa cacaatgcgt
       61 aagtctctta atactctttg acgccctcga aatcgttcat tgcttaagac gcgttctagt
      121 tcttcttgtt tctctttact ttgtttgttt ctataatctc ttagtgtttc atgaaagaga
      181 taataatcat ctagccagag acccccctca cttatacgat gactgatctc tcccacttct
      241 tcatagggtt ctttatcgta tctacgcttc tgactttcct gcttacggat atagtctaaa
      301 attcgatttc gaaacttggt tttgaaatat ttccttaaac gtggaatatc gtctaccagt
      361 ccttcttctc tactaatcaa ttcatgtaag cagagcatgc cttcttggtc ccaatccgac
      421 aattcccata aatgaaggta atattcattt ctacacttat aaacagtccc ttggacttct
      481 tcatacaatt ctttaatcat aattttcccc tttctagata cagtctaaca gattagaaaa
      541 cacatttgtt ccattttctc cattctgttc cctttagctc ctaaactgca caaaaaaga
//
LOCUS       DAVBNZ010000120          586 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000120 DAVBNZ010000000
VERSION     DAVBNZ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.121"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(<1..204)
                     /locus_tag="VQ860_002127"
     CDS             complement(<1..204)
                     /locus_tag="VQ860_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3120472.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKYAKGG
                     RKPKLSLEDLLMATLQYVREYRTY"
     gene            199..453
                     /locus_tag="VQ860_002128"
     CDS             199..453
                     /locus_tag="VQ860_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3120473.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGEHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
BASE COUNT          189 a           86 c          116 g          195 t
ORIGIN      
        1 ataagtgcga tattctcgca catattgaag agtggccata agaaggtctt ctaggcttaa
       61 tttaggtttt cgtccacctt ttgcgtattt aagttgataa gctgttttta atacagctaa
      121 tatctcttca aaagtcgtgc gctgaacacc aacaagacgc ttaaatcgtg catcagttag
      181 ttgtttactt gcttcataat tcatagaact actataccat attttgtttc gcaggaagtc
      241 tattggaaag taagaaatat tggagctgag gcgattagaa gaaattgtga gcgtggtgct
      301 attttttcag gtaaaataaa acatcacgaa gattctcagt ttaaaggaga gcactatgtt
      361 gaatgttatg ctgttttaga taatacggtt atagcaagag atagaataac agtccctatc
      421 gatccgttat gtggaaaaga ttttatagag tagcatataa ttgattctta actggaatac
      481 tctctatctc tttacatcaa gaaaatgact aaacagggaa gtttgccttc ttcccttttt
      541 ttgttatact agtagaagaa aaaaatagaa agatttgtgg gagtga
//
LOCUS       DAVBNZ010000121          558 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000121 DAVBNZ010000000
VERSION     DAVBNZ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..558
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.122"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..386
                     /locus_tag="VQ860_002129"
     CDS             <1..386
                     /locus_tag="VQ860_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3120474.1"
                     /translation="SRYENGTSSVSTELIDIICQKFNVSYVDIVGEDKMLNPVEDYEL
                     TLKIEIVKERGANLLSRLYRYQDSQGISIDDESNPWILMSDDLSDLIHTNIYLVETFD
                     EIERYSGYLDGIERMLEISEKRMVA"
     gene            386..>558
                     /locus_tag="VQ860_002130"
     CDS             386..>558
                     /locus_tag="VQ860_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3120475.1"
                     /translation="MEIQDYTDSEFKHALTRNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQG"
BASE COUNT          195 a           74 c          120 g          169 t
ORIGIN      
        1 tgagtcgtta tgaaaatgga acgagttcag tctctaccga attaatagac atcatttgtc
       61 agaagtttaa tgtatcttat gtcgatattg taggagaaga taaaatgctc aatcctgttg
      121 aagattatga attgactttg aaaattgaaa ttgtgaaaga aagaggtgct aatctattat
      181 ctcgactcta tcgttatcaa gatagtcagg gaattagcat tgatgatgaa tctaatcctt
      241 ggattttaat gagtgatgat ctatctgact tgattcatac gaatatctat ttagtagaaa
      301 cttttgatga aatagagagg tatagcggct atttggatgg aattgaacgt atgttagaga
      361 tatctgaaaa acggatggta gcctaatgga aatccaagat tatactgata gtgaattcaa
      421 acatgctcta acacggaatc ttcgttcact gacaagagga aaaaagtcca gtaagcaacc
      481 tatagcgatt ttgcttggag ggcaaagtgg tgccggtaaa actacaattc atcggattaa
      541 acagaaagaa tttcaagg
//
LOCUS       DAVBNZ010000122          536 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000122 DAVBNZ010000000
VERSION     DAVBNZ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.123"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(<1..534)
                     /locus_tag="VQ860_002131"
     CDS             complement(<1..534)
                     /locus_tag="VQ860_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3120476.1"
                     /translation="MEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAAEQGGAVGIR
                     ANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIEVIALDCTKR
                     ERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTLSGYTSYSPK
                     VDGPDFELIKKLCDAGVD"
BASE COUNT          141 a          133 c          103 g          159 t
ORIGIN      
        1 atctacaccg gcatcacaga gtttcttaat caattcaaaa tctggaccgt ctacttttgg
       61 actgtaggat gtgtagcctg ataaggttgt tccgacaaag tcaattcctg cttctacagc
      121 tgctagccct tcttcgaaga tactagtatc agccatcaaa agctgattag gatatttctc
      181 cttaacctga cgaatgaact cttgaatttc caaaccatcg tagcgttcac gcttggtaca
      241 atccagagca atcacctcga tgtccagttc tgccaattca tcaacttctt tcatagtagc
      301 cgtgatgaag ggttcctgag gtggataatc acgtttgata atcccaatga ttggaagttt
      361 agtgacttcc ttaatttcct tgatatcgcg aacactgttt gctcggatac cgactgctcc
      421 accttgctca gccgctttga ccagcaaggg aatcacccct cccgcttctg tataaagcgg
      481 ttcatgagga agagcctgac aagaaacgat gattccatct ttgatttgct caatca
//
LOCUS       DAVBNZ010000123          535 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000123 DAVBNZ010000000
VERSION     DAVBNZ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.124"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(<1..110)
                     /locus_tag="VQ860_002132"
     CDS             complement(<1..110)
                     /locus_tag="VQ860_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3120477.1"
                     /translation="MVNCEPLEAYRQLAEAELVGCWAHVRRKFFEATPKQA"
     gene            complement(183..410)
                     /locus_tag="VQ860_002133"
     CDS             complement(183..410)
                     /locus_tag="VQ860_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3120478.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
BASE COUNT          155 a          125 c          108 g          147 t
ORIGIN      
        1 gcttgcttgg gggtcgcttc aaaaaatttc cttctcacat gcgcccaaca tccaacaagt
       61 tcagcttctg ccagttgacg ataagcttct agcggttcgc agtttaccaa gcttagcgtc
      121 gccttgctcc taaaccttgg actgctatcg cataggcaga actagaggac taaagtccta
      181 agttactgcc gcaacatatc acaatgaaca tagccagaat aatctcctag gaattcttgt
      241 actaccgaac cactccgact ctgatcatga tggtacagcg tgattgcttg attctcaact
      301 ttcccagaca aaaaggtcca atagtaggtc agatggctat gactctctag aacccgataa
      361 gaagtttcat ccgcatgaag taagggctga gtcaatagtc tctctcgcaa gaggttataa
      421 aggggcttta ggaataggag ctttcacaag cttatccaga tgattatctt ttactcgtta
      481 tggacaatgc tatatggcat aaatcaagta ccttaaagat tccgactaat attgg
//
LOCUS       DAVBNZ010000124          518 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000124 DAVBNZ010000000
VERSION     DAVBNZ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..518
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.125"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            1..518
                     /locus_tag="VQ860_002134"
                     /pseudo
     CDS             1..518
                     /locus_tag="VQ860_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          198 a           88 c          108 g          124 t
ORIGIN      
        1 cgttactatt ctcctgattt aaaacaagaa atgattcata aagtctgaca tgaaggctag
       61 actaaagata gagtttctct tgaatacggt ctcccaagtc gtacgatact tcttaactgg
      121 ctagcacaat acaggaaaaa cgggtatact attgttgaga aaccaagagg gagagtacct
      181 aaaatgggac gtaagccaag aacgagacct gaagagagga cagaattaga acgtcttcaa
      241 gcagaaaatg agtacctgag agcggagaat gccatcctaa aaaagttaag agaactccga
      301 ttgaaggagg aaaaagagaa agaagaaaga tagaaattgt tcaagaatta atgactgagt
      361 tttcgttaga tcttcttcta aaagccatta aactagctcg ttggacctac tactatcact
      421 tgaaacagtt agacaaacca gataaggacc aagagcttaa agctgaaatt caattcattt
      481 ttatcgaaca caagggaaat tatacttatc gccgggtt
//
LOCUS       DAVBNZ010000125          505 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000125 DAVBNZ010000000
VERSION     DAVBNZ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.126"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            1..505
                     /locus_tag="VQ860_002135"
                     /pseudo
     CDS             1..505
                     /locus_tag="VQ860_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT          153 a           99 c          113 g          140 t
ORIGIN      
        1 aggagttcgg actcgactct ctccttcaag aaacacgtgg tggtcgtaac catgcatata
       61 tgacagttga ggaagagaaa gcctttcttg cccgccattt gaaggctaca gaggcaggag
      121 aatttgttac aattgatgcc ttatttcagg cttataaaaa ggagttaggt cattcctaca
      181 cacgtgatgc cttctatcaa ctgttgaagc gccatggttg gcgaaatatt acgccacgtc
      241 cagaacatcc taagaaagca gacgctcaaa ccattgttgc gtctaaaaat aaaatctcaa
      301 ttcaagaaga caagaaagcg ttttaaatat agtagacgtt ttcataaggt tcgcttgatg
      361 taccaagatg aggctggttt cggtagaatc agtaaactgg gatcttgttg gtctccaata
      421 ggagtaggtc cacatgtcca tagtcactat atacgagaat ttcgctatta ttatggagct
      481 gttgatgcct atacaggcga atcat
//
LOCUS       DAVBNZ010000126          501 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000126 DAVBNZ010000000
VERSION     DAVBNZ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.127"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..>501
                     /locus_tag="VQ860_002136"
     CDS             <1..>501
                     /locus_tag="VQ860_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3120479.1"
                     /translation="FGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKN
                     VTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRIN
                     SGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQN
                     EFADFVV"
BASE COUNT          191 a           75 c           83 g          152 t
ORIGIN      
        1 gtttggggaa aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga
       61 taggggcaaa aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt
      121 aaatacaaag aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa
      181 aacaaaggat aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac
      241 aagaggtact gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg
      301 tataaattca ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat
      361 tatccatgtt ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca
      421 gttaccaatt acaaaattaa aaaaaatact tctccccctc cccccactag ccctccaaaa
      481 tgagttcgca gactttgtag t
//
LOCUS       DAVBNZ010000127          476 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000127 DAVBNZ010000000
VERSION     DAVBNZ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.128"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(91..228)
                     /locus_tag="VQ860_002137"
     CDS             complement(91..228)
                     /locus_tag="VQ860_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3120480.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            complement(372..446)
                     /locus_tag="VQ860_002138"
                     /pseudo
     CDS             complement(372..446)
                     /locus_tag="VQ860_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
BASE COUNT          170 a           79 c           69 g          158 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 agcctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttgacaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattaa tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagcc ccaattattc acccctaatc taaaaa
//
LOCUS       DAVBNZ010000128          397 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000128 DAVBNZ010000000
VERSION     DAVBNZ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.129"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(<1..>397)
                     /locus_tag="VQ860_002139"
     CDS             complement(<1..>397)
                     /locus_tag="VQ860_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3120481.1"
                     /translation="KTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSETL
                     YQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKE
                     MKEGFFGDKTDSSTLIKNEVRMMMSCIAYN"
BASE COUNT          101 a           83 c           93 g          120 t
ORIGIN      
        1 gattgtaggc gatacagctc atcatcatac gaacttcgtt tttgattaag gttgaactat
       61 ccgttttatc gccaaaaaat ccctccttca tctccttgat gaaattctcg gcttgaccac
      121 gtccacgata aagctgaaac tggtcttggc ttgttccact cgtcatattt gtaacgagag
      181 aaataacatc gtagaacaag tttccttctt ttcgttcaga gaactggcag acacgacgct
      241 tgtgcgacca agatcctgct tgatagagag tttctgagta ggcggagtgg ggcaagatgg
      301 ttaagtcctc atcctgtggg caagggaggg aaaggtctcc aagacggctc agaacagtat
      361 ttttcttgag ttttatgagg tagtattgcc ctgtttt
//
LOCUS       DAVBNZ010000129          377 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000129 DAVBNZ010000000
VERSION     DAVBNZ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.130"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            complement(1..377)
                     /locus_tag="VQ860_002140"
                     /pseudo
     CDS             complement(1..377)
                     /locus_tag="VQ860_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          100 a           67 c           71 g          139 t
ORIGIN      
        1 agtacttact ggaatggcaa attcagtcac atctgtgtag cactgttcca ttgttttaga
       61 gccttcaaat tggccttgaa tgagattctc tgccttcttg ccaacgtctc ctttaatgag
      121 aagaatattt tcgtttctgt cgcgttttag cttgtaaatt gagtactttc atcaagcctt
      181 gaactctttt atgatttacc agataagcac gatttcttag ttctaaatga atacagcgat
      241 aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta agctcttggt
      301 ccttatctgg tttgtctagc tgtttcaagt gatagtagta ggtccaacga gctagtttaa
      361 tagcttttag aagaaga
//
LOCUS       DAVBNZ010000130          348 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000130 DAVBNZ010000000
VERSION     DAVBNZ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..348
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.131"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            239..348
                     /locus_tag="VQ860_002141"
                     /pseudo
     CDS             239..348
                     /locus_tag="VQ860_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          128 a           49 c           63 g          108 t
ORIGIN      
        1 aagaacagta caaatcgatc aggacagtca aattgatttc taacaatgtt ttagaagtag
       61 aggtgtatta ttctagtttc aatctattat atttcgtctg atgggcaaat cttataaaga
      121 gattatagaa cttttatagt agtttgaaat aagatgtgaa caactctatc aggaaagtca
      181 aattaattta tagaaatatt ttagcagcca aggtgtactg ttatagattc aatacactat
      241 agactgtaat caaacaacga tttggcgaaa tgtaaaaaaa tatgaggagt tcggactcga
      301 ctctctcctt caagaaacac gtggtggtcg taaccatgca tatatgac
//
LOCUS       DAVBNZ010000131          297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000131 DAVBNZ010000000
VERSION     DAVBNZ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.132"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            116..>297
                     /locus_tag="VQ860_002142"
     CDS             116..>297
                     /locus_tag="VQ860_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HET3120482.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCR"
BASE COUNT           95 a           57 c           49 g           96 t
ORIGIN      
        1 cttagatcct ggatggtttc ttttttcacc caatgggtgt tttttactag acaaaaaaga
       61 gtttcccctt tatggtataa gtgtagaaaa aaacacaaaa agaaaggaaa ctcacatgaa
      121 cagtttacca aatcatcact tccaaaacaa gtctttttac caactatctt tcgatggagg
      181 tcatttaacc cagtatggtg gtcttatctt ttttcaggaa cttttttccc agttgaaact
      241 aaaagagcgg atttctaagt atttagtaac gaatgaccaa cgccgctact gtcgtta
//
LOCUS       DAVBNZ010000132          284 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000132 DAVBNZ010000000
VERSION     DAVBNZ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.133"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
BASE COUNT           86 a           55 c           79 g           64 t
ORIGIN      
        1 tctgaggtgt aagtcctcgg tgggcacctg ttaccggtga acccaatagc gattcccaag
       61 cctgactatc gtgaggtagc ggattaaaac ggtctgggga tagaccgttt taaatctgac
      121 gctggaaata agaatcgtca gaggaaggga tagcgaactc gtggctctac gaacaggaac
      181 gtgatagtaa ggcgtatata gcggataagg gggcctcaaa ctctaaagtt caaaaaggta
      241 gtcgtaacct atatgcgtaa atcacgagag caactgaatt tgtc
//
LOCUS       DAVBNZ010000133          263 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000133 DAVBNZ010000000
VERSION     DAVBNZ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..263
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.134"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            1..73
                     /locus_tag="VQ860_002143"
     tRNA            1..73
                     /locus_tag="VQ860_002143"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Met,seq:cat)
     gene            87..160
                     /locus_tag="VQ860_002144"
     tRNA            87..160
                     /locus_tag="VQ860_002144"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            171..260
                     /locus_tag="VQ860_002145"
     tRNA            171..260
                     /locus_tag="VQ860_002145"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Ser,seq:tga)
BASE COUNT           53 a           66 c           76 g           68 t
ORIGIN      
        1 gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg gggttcgatc
       61 cccttcgccg ctataatgat cttgtcggac ctttagctca gctggttaga gctctcggct
      121 cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt ggaggattac
      181 ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg
      241 ttcgaatccc acatcctcct ttt
//
LOCUS       DAVBNZ010000134          251 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000134 DAVBNZ010000000
VERSION     DAVBNZ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..251
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.denovo.135"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..>251
                     /locus_tag="VQ860_002146"
     CDS             <1..>251
                     /locus_tag="VQ860_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3120483.1"
                     /translation="PIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDI
                     TSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKG"
BASE COUNT           84 a           51 c           60 g           56 t
ORIGIN      
        1 ccgattcgtc atccagaacg tttaggaaaa ccaaatgcgc aaattaccta cactgatgat
       61 gagattcaag tagccaagtt ggcaggcaag tacacaacag aagacggtta tatctttgat
      121 cctcgtgata taaccagtga tgagggggat gcctatgtaa ctccacatat gacccatagc
      181 cactggatta aaaaagatag tttgtctgaa gctgagagag cggcagccca ggcttatgct
      241 aaagagaaag g
//
LOCUS       DAVBNZ010000135         9429 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 828-06
            SAMEA1012479-rid20177653.guided.074, whole genome shotgun sequence.
ACCESSION   DAVBNZ010000135 DAVBNZ010000000
VERSION     DAVBNZ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012479
            Sequence Read Archive: ERR059361
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979951.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979951.1
            Genome Coverage       :: 612x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 01:47:24
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,157
            CDSs (total)                      :: 2,114
            Genes (coding)                    :: 1,982
            CDSs (with protein)               :: 1,982
            Genes (RNA)                       :: 43
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 38
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 132
            CDSs (without protein)            :: 132
            Pseudo Genes (ambiguous residues) :: 0 of 132
            Pseudo Genes (frameshifted)       :: 81 of 132
            Pseudo Genes (incomplete)         :: 52 of 132
            Pseudo Genes (internal stop)      :: 32 of 132
            Pseudo Genes (multiple problems)  :: 29 of 132
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9429
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012479-rid20177653.guided.074"
                     /strain="NIG 828-06"
                     /db_xref="taxon:1313"
     gene            <1..1066
                     /locus_tag="VQ860_002147"
     CDS             <1..1066
                     /locus_tag="VQ860_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3120484.1"
                     /translation="KRAITKLFNTILTRAGITLIITTAFSISTMLYTLSAGYPFFLIA
                     FLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRVMRKPRMLMHAHMHRLQRKLGRSM
                     TTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGKEKSTLGKRIGQTIGTVADTKDRM
                     VDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRDLTSSISQTKADRASGRKEQQEQR
                     RKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQYHDEQTSKQSNIQTSYKESQQAKQ
                     ERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTTADRTSQRPITKERPSTVQRVPLQ
                     NTRSRPPIKTATIKKVGKKP"
     gene            1063..2064
                     /locus_tag="VQ860_002148"
     CDS             1063..2064
                     /locus_tag="VQ860_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3120485.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            2061..2996
                     /locus_tag="VQ860_002149"
     CDS             2061..2996
                     /locus_tag="VQ860_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3120486.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            3241..3357
                     /locus_tag="VQ860_002150"
     CDS             3241..3357
                     /locus_tag="VQ860_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3120487.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            3373..5292
                     /gene="tet(M)"
                     /locus_tag="VQ860_002151"
     CDS             3373..5292
                     /gene="tet(M)"
                     /locus_tag="VQ860_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3120488.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            5411..5578
                     /locus_tag="VQ860_002152"
     CDS             5411..5578
                     /locus_tag="VQ860_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3120489.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(5638..5991)
                     /locus_tag="VQ860_002153"
     CDS             complement(5638..5991)
                     /locus_tag="VQ860_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3120490.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            6496..6918
                     /locus_tag="VQ860_002154"
     CDS             6496..6918
                     /locus_tag="VQ860_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3120491.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            6915..7145
                     /locus_tag="VQ860_002155"
     CDS             6915..7145
                     /locus_tag="VQ860_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3120492.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            7606..7809
                     /locus_tag="VQ860_002156"
     CDS             7606..7809
                     /locus_tag="VQ860_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3120493.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            7891..9108
                     /locus_tag="VQ860_002157"
     CDS             7891..9108
                     /locus_tag="VQ860_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3120494.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
BASE COUNT         3216 a         1649 c         1902 g         2662 t
ORIGIN      
        1 aaaacgagcc ataacaaagc tctttaatac cattttgaca cgagctggaa tcacattgat
       61 tattacgaca gcatttagta tttcaaccat gctctatacc ttatcggctg gttatccgtt
      121 ctttttgatt gcttttctac agattgtgac ctttgcagga atctacttca agctgggcga
      181 tttaatgagt atgttttctc tacagagtaa cgattctcaa agtgtgggaa gtcgtgtgat
      241 gagaaaacct cgtatgctta tgcacgctca catgcaccgt ctacagcgga aacttggacg
      301 ttccatgact actctagggg ctgggtctgc cattgttaca ggtaaaaaag gacagtcggg
      361 ttcggggagt tctgcaagga cacaagcaga tcactcccga ccagacggaa aggaaaaatc
      421 aacacttgga aaacgtatcg gtcaaaccat cggtacagta gctgatacca aagacagaat
      481 ggtagacact gctagtggtt tgaaagaaca ggttaaagat ttgccgacca atgcaagata
      541 tgcagtatat caaggaaaat ccaaagtaaa agagaatgtc cgtgatttaa ccagtagtat
      601 ttctcaaacc aaagcggaca gagccagtgg acgcaaggaa cagcaggaac aaaggcgaaa
      661 aaccattgcg aagcgtcgct ctgaaatgga acaggtcaaa cagaaaaaac agcctgcttc
      721 ttctgttcat gaaagaccga ctacaagaca agaacaatat catgatgaac agacctcaaa
      781 acagtctaat attcagactt catataagga atctcaacaa gccaaacaag agcgtccagc
      841 agttaagtcc gatttttcaa gtccaaaagt ggaacgccaa ggcaataccg ttcaagaaaa
      901 aaccgttcaa aagccagcaa cttcaaccac tacagcagat agaacttcac aacgtccaat
      961 cacaaaagaa cgtccgtcta ctgttcaaag agtaccacta caaaatacaa gaagtagacc
     1021 accaatcaaa accgccacca ttaagaaagt cggtaagaaa ccatgaagtt gaaaacttta
     1081 gtgattggtg gttctggatt attcttgatg gtcttctcac tgcttctgtt tgttgccatt
     1141 ttattttcag atgaacagga cagcggaatt tccaatattc attatggagg tgtgaatgtt
     1201 tccgcagaag tgctggctca taagcctatg gtagaaaaat atgccaaaga atatggcgtt
     1261 gaagaatatg tcaacatact tcttgcgatt atacaggtgg aatcgggcgg tactgcggaa
     1321 gatgttatgc agtcctcgga atccctcggt cttccaccta attcattgag tacagaagaa
     1381 tccattaagc aaggtgtgaa gtatttcagt gaattattag ccagtagcga aaggctcagt
     1441 gtagatttag aatcggttat ccagtcctac aattatggtg gtggtttctt agggtatgtg
     1501 gctaatcgtg gaaataaata tacctttgaa ctggctcaaa gtttctcaaa agagtattca
     1561 ggtggcgaaa aagtgtctta ccccaatccc atagccatac ctatcaatgg gggctggcga
     1621 tacaactatg gcaatatgtt ttatgtgcaa ctggtaacgc agtatcttgt cacaacagag
     1681 tttgatgatg atacggtaca agccatcatg gacgaagcac tgaaatatga gggctggcga
     1741 tacgtttacg gtggagcttc cccgactact tcttttgatt gtagcggact gacacaatgg
     1801 acgtatggaa aagctggaat taacttacca cgaaccgcac aacagcaata tgatgtgacc
     1861 cagcatatcc cactatcgga agcacaagct ggcgatttgg ttttctttca ttctacctat
     1921 aacgctggct cttatattac tcatgttggg atataccttg gcaataaccg tatgtttcat
     1981 gcaggcgacc caatcggtta tgccgactta acaagcccct actggcaaca gcatttagtg
     2041 ggagcaggac gaatcaaaca atgagaaagg aagatttaat gatgaaattt agaaaaaatc
     2101 agaataaaga aaaacagata ccaaaggaaa agaaacctcg tgtctactat aaggtcaatc
     2161 ctcataaaaa ggttgtgatt gccttgtggg tacttttagg gcttagtttc agctttgcga
     2221 tattcaagca ctttacagct atagatactc atactattca cgaaacaact atcatagaaa
     2281 aggaatacgt tgatactcat catgtagaaa attttgtaga gaactttgcg aaagtctact
     2341 attcatggga gcaatccgat aagtccattg ataatcgaat ggaaagtcta aaaggctatc
     2401 tgacagatga acttcaagct ctcaatgttg atacagtacg caaagatatt cctgtatcgt
     2461 cttctgtaag aggatttcag atatggacgg tagagccaac tggcgacaat gagtttaatg
     2521 taacctacag tgtagaccag ctcattacag agggagaaaa tacaaagacc gtccactctg
     2581 cttatatagt gagtgtctat gtagatggtt ctggaaatat ggtactggtt aagaatccga
     2641 ccattaccaa catacctaag aaatcaagtt ataaaccaaa agccattgaa agtgagggga
     2701 cggttgattc cattacaacc aatgaaatca atgagttttt aacgacgttc ttcaagctct
     2761 atcctacagc gacagccagt gaactttcct actatgtgaa tgacgggata ttaaaaccaa
     2821 tcggaaaaga gtacatcttt caagaactgg taaatcctat tcacaatcgt aaggataatc
     2881 aagtcacggt atcgctgaca gtggagtata tcgaccagca gaccaaagca acgcaggtat
     2941 ctcaatttga tttggtactt gaaaagaacg ggagtaattg gaagattata gaataacaaa
     3001 tattggtaca ttattacagc tattttgtaa tcacgtactc tctttgataa aaaattggag
     3061 attcctttac aaatatgctc ttatgtgcta ttatttaagt atctatttaa aaggagttaa
     3121 taaatatgcg gcaaggtatt cttaaataaa ctgtcaattt gatagtggaa acaaataatt
     3181 ggatgtcctt ttttaggagg gcttagtttt ttgtacccag tttaagaata cctttatcat
     3241 gtgattctaa agtatccgga gaatatctgt atgctttgta tgcctatggt tatgcataaa
     3301 aatcccagtg ataagagtat ttatcactgg gatttttatg cccttttggg cttttgaatg
     3361 gaggaaaatc acatgaaaat tattaatatt ggagttttag ctcatgttga tgcgggaaaa
     3421 actaccttaa cagaaagctt attatataac agtggagcga ttacagaatt aggaagcgtg
     3481 gacagaggta caacgaaaac ggataatacg cttttagaac gtcagagagg aattacaatt
     3541 cagacggcga taacctcttt tcagtggaaa aatactaaga taaacatcat agacacgcca
     3601 ggacatatgg attttttagc agaagtatat cgttcattat cagtattaga tggggcaatt
     3661 ctactgattt ctgcaaaaga tggcgtacaa gcacaaactc gtatattgtt tcatgcactt
     3721 aggaaaatag gtattcccac aatctttttt atcaataaga ttgaccaaaa tggaattgat
     3781 ttatcaacgg tttatcagga tattaaagag aaactttctg cggaaattgt aatcaaacag
     3841 aaggtagaac tgcatcctaa tatgcgtgta atgaacttta ccgaatctga acaatgggat
     3901 atggtaatag aaggaaatga ttaccttttg gagaaatata cgtctgggaa attattggaa
     3961 gcattagaac tcgaacaaga ggaaagcata agatttcata attgttccct gttccctgtt
     4021 tatcacggaa gtgcaaaaaa caatataggg attgataacc ttatagaagt gattacgaat
     4081 aaattttatt catcaacaca tcgaggtcag tctgaacttt gcggaaaagt tttcaaaatt
     4141 gagtattcgg aaaaaagaca gcgtcttgca tatatacgtc tttatagtgg cgtactgcat
     4201 ttgcgagatt cggttagaat atcggaaaag gaaaaaataa aaattacaga aatgtatact
     4261 tcaataaatg gtgaattatg taaaatcgat aaggcttatt ccggggaaat tgttattttg
     4321 cagaatgagt ttttgaagtt aaatagtgtt cttggagata caaagctatt gccacagaga
     4381 gagagaattg aaaatcccct ccctctgctg caaacgactg ttgaaccgag caaacctcaa
     4441 caaagggaaa tgttacttga tgcactttta gaaatctccg acagtgaccc gcttctgcga
     4501 tattatgtgg attctgcgac acatgaaatc atactttctt tcttagggaa agtacaaatg
     4561 gaagtgactt gtgctctgct gcaagaaaag tatcatgtgg agatagaaat aaaagagcct
     4621 acagtcattt atatggaaag accgttaaaa aaagcagagt ataccattca catcgaagtt
     4681 ccaccgaatc ctttctgggc ttccattggt ctatctgtag caccgcttcc attagggagc
     4741 ggagtacagt atgagagctc ggtttctctt ggatacttaa atcaatcgtt tcaaaatgca
     4801 gttatggagg ggatacgcta tggctgtgaa caaggattgt atggttggaa tgtgacggac
     4861 tgtaaaatct gttttaagta tggcttatac tatagccctg ttagtacccc agcagatttt
     4921 cggatgcttg ctcctattgt attggaacaa gtcttaaaaa aagctggaac agaattgtta
     4981 gagccatatc ttagttttaa aatttatgcg ccacaggaat atctttcacg agcatacaac
     5041 gatgctccta aatattgtgc gaacatcgta gacactcaat tgaaaaataa tgaggtcatt
     5101 cttagtggag aaatccctgc tcggtgtatt caagaatatc gtagtgattt aacttccttt
     5161 acaaatggac gtagtgtttg tttaacagag ttaaaagggt accatgttac taccggtgaa
     5221 cctgtttgcc agccccgtcg tccaaatagt cggatagata aagtacgata tatgttcaat
     5281 aaaataactt agtgtatttt atgttgttat ataaatatgg tttcttgtta aataagatga
     5341 aatatttttt aataaagatt tgaattaaag tgtaaaggag gagatagtta ttataaacta
     5401 caagtggata ttgtgtcctg tatgtggaaa taaaacacga ttaaagataa gggaagatac
     5461 tgaattaaaa aaattccccc tctattgtcc gaaatgcaga caagaaaatt taattgaaat
     5521 aaagcagttc aaagtaactg tgattacaga gccagacgca aagacgcaga gccgataaaa
     5581 tgagattaat acaatctcat tttatcggct ctttccgtta tgtatggatt cttttaatta
     5641 gtcttcgatg tttcttgctt cgttgatacc gctggctaaa gattccatta aggatagttc
     5701 tttgtctgta aagctatcca tgtatttctc tatctgtaat cgtcgggtgc tttttaccaa
     5761 gttattagca ggtaagaaaa attcatcaac ggaaacatga agtaacgata caaggtcata
     5821 aagaacttgt atgctggggt gttgcccttt attttcaata ttagttaagt accgtgggtc
     5881 aatttcaatc aatgctccca cttgttcacg agttaaacct cgtttcaatc gagcttcttt
     5941 aatggctaaa ccaaaggctc taaaatcata tttatcttct tttttacgca tagtagacca
     6001 cctctataca ttttattgtt cctactgaat taaaaacagg tatagaaaaa cgtgttatat
     6061 ggtttatagg tttatattta ataaaaagca ctactaaacg ccaataaaaa aaaccgttat
     6121 atggtagtgc tatttacgct gttaaaatat tgtatattac ttccaaatgg cggtttgttg
     6181 gaggtcaacg tcgccatgaa gtacatcata tacaataaat ttccttacat tgggttcttg
     6241 tcaaaaaaag tcgtctatct gcaatagata agtacgtcca ccaatgtggt tttataaatc
     6301 atatagatag aataacagaa gcatgtaaac agagaaataa atctgtttat atgctttttt
     6361 ggctattcag aactttttta caaagtttat ttatcagtaa tgcaacaaat ccccctttca
     6421 cattgggact aagagtgaaa ggagataaac gagcaaggct cacttccttt cctagacaga
     6481 aagggggtga gaaacatgaa accatcttct tttcagacca caatagaaaa tcagtttgac
     6541 tatatctgta aacgtgctat ggaagacgag cgaaagaatt atatgcttta tctttcaagg
     6601 attgcaaagc gtgaggtgtc cttttcggat gttggcgatt atcttgttag ccagtttgcg
     6661 acaacagata actattcaac tgactttcag atttttacac tcaatgggtt atcagtaggc
     6721 gttgaaaatg atttgttgag tgaagcatta cgtgagttgc cagacaagaa acgtgaaatt
     6781 ctactgctgt tttactttat ggacatgagc gattcagaaa ttgcagacct gttgaaattg
     6841 aaccgttcta ctgtctatcg gcatagaacc agtggactag ccttaattaa aaagtttatg
     6901 gaggaatttg aagaatgaaa acacaatatc ctatgattcc ctttcctctc attgtaaagg
     6961 caacagatgg cgataccgaa gcgattaacc agattctaca tcattacaga gggtacataa
     7021 cgaagcgttc cctacgactt atgaaagatg aatatggcaa tcaaagtatg gtcgttgatg
     7081 aagtcttacg tggaagaatg gaaaccagac tgattacaaa gattttgtca tttgaaatta
     7141 agtaatatcc tctctccttt cgtggaagcg tgctaaacca ttccacgctt cccgaacagg
     7201 gaggtttgtt attccaccaa agcatattga gctttcaatg tgttttgata ggctaacgag
     7261 ccattgttct ttgaaaactg aataaaagta atcgaatacg tttcgataag aaaagagcca
     7321 acggaactaa ccgccatgac ctatcttata aagatagcga gcgattcatg ttagtgatcc
     7381 gagaagcaat ctttagcagg attgcctgca acgacattct tatcgtgata atgatactcc
     7441 catacagtca atagtccgag cgtgataaaa ccgtcgcagg caatgagtat ggctacatga
     7501 gaaccatgca ggggtggaac tcccgtgagc tttgctaaag ctgttcgatt gctggtaaaa
     7561 caacttttat gaaatccaaa taagtgattt ggaaaggagg attttatgaa gcagactgac
     7621 attcctattt gggaacgtta taccctaacc attgaagaag cgtcaaaata ttttcgtatt
     7681 ggcgaaaaca agctacgacg cttggcagag gaaaataaaa atgcaaattg gctgattatg
     7741 aatggcaatc gtattcagat taaacgaaaa caatttgaaa aaattataga tacattggac
     7801 gcaatctagc gtcgccaaag ggtcttgtat atgataaaat agtattaagt cgtatcaagg
     7861 ctctttccat aaaggaaagg agcaaatgcc atgtcagaaa aaagacgtga caataaaggt
     7921 cgaatcttaa agactggaga gagccaacga aaagacggaa gatacttata caaatatata
     7981 gattcatttg gagaaccgca atttgtttac tcgtggaaac ttgtggctac agaccgagta
     8041 ccagcaggaa agcgtgattg tatctcactt agagagaaaa tcgcagagtt acagaaagac
     8101 attcatgatg gtattgatgt tgtaggaaag aaaatgacac tctgccagct ttacgcaaaa
     8161 cagaacgctc aaagaccaaa ggttagaaaa aacactgaaa ctggacgcaa atatcttatg
     8221 gatattttga agaaagacaa gttaggtgta agaagtattg acagtattaa gccatcagac
     8281 gctaaagaat gggctattag aatgagtgaa aatggttatg cttatcaaac catcaataac
     8341 tacaaacgtt ctttaaaggc ttcattctat attgctatac aagatgattg tgttcggaag
     8401 aatccatttg actttcaact gaaagcagtt cttgatgatg atactgtccc taagaccgta
     8461 ctaacagaag aacaggaaga aaaactgtta gcctttgcaa aagctgataa aacctacagc
     8521 aaaaattatg atgaaattct gatactctta aaaacaggtc ttcgtatttc agagtttggt
     8581 ggtttgacac ttccagattt agattttgag aatcgtcttg tcaatataga ccatcagcta
     8641 ttgagagata ctgaaattgg gtactacatt gaaacaccaa agaccaaaag tggcgaacgt
     8701 caagttccta tggttgaaga agcctatcaa gcatttaagc gagtgttagc gaatcgaaag
     8761 aatgataagc gtgttgagat tgatggatat agtgatttcc tctttcttaa tagaaagaac
     8821 tatccaaaag tggcaagtga ttacaacggc atgatgaaag gtcttgttaa gaaatacaat
     8881 aagtataacg aggataaatt gccacacatc actccacata gtttgcgaca tacattctgt
     8941 accaactatg caaatgcagg aatgaatcca aaggcattac agtacattat gggacatgct
     9001 aatatagcca tgacgctgaa ctattacgca catgcaacat tcgattctgc aatggcagaa
     9061 atgaaacgct tgaataaaga gaagcaacag gagcgtcttg ttgcttagta gtacaaatga
     9121 atttactact tatttaccac ttctgacagc taagacatga ggaaatatgc aaagaaacgt
     9181 gaagtatctt cctacagtaa aaatactcga aagcacatag aataaggctt tacgagcatt
     9241 taagaaaata taaaaagata attagaaatt tatactttgt ttttattaaa aagcagcaaa
     9301 ctataaacta gtaggttcca cactaaatgt agccccatac tgccccacaa gtccgattta
     9361 tagcgtacca tccctaaaaa cattcccaat gaaacatata aacaccaagc tagaatggtt
     9421 cctggatga
//
